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ONTOLOGY REPORT - ANNOTATIONS


Term:heart induction
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Accession:GO:0003129 term browser browse the term
Definition:The close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.


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BMP signaling pathway involved in heart induction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19736317) BHF-UCL PMID:19736317 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181
JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in ISO (PMID:20702560) BHF-UCL PMID:20702560 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303
JBrowse link
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) BHF-UCL PMID:19736317 NCBI chrNW_004955583:995,707...1,003,202 JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:19736317) BHF-UCL PMID:19736317 NCBI chrNW_004955581:351,375...382,541
Ensembl chrNW_004955581:350,889...382,541
JBrowse link
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (MGI:3835736|PMID:18297060) BHF-UCL PMID:18297060 MGI:3835736 NCBI chrNW_004955425:7,353,964...7,357,599 JBrowse link
G Wnt11 Wnt family member 11 involved_in ISO (MGI:5424267|PMID:22569553) CACAO PMID:22569553 MGI:5424267 NCBI chrNW_004955414:15,674,478...15,694,758
Ensembl chrNW_004955414:15,674,940...15,694,883
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (MGI:5424267|PMID:22569553) CACAO PMID:22569553 MGI:5424267 NCBI chrNW_004955430:5,304,817...5,325,684
Ensembl chrNW_004955430:5,304,745...5,325,684
JBrowse link
positive regulation of Notch signaling pathway involved in heart induction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata5 GATA binding protein 5 involved_in ISO (MGI:5286818|PMID:21633169) BHF-UCL PMID:21633169 MGI:5286818 NCBI chrNW_004955528:1,595,231...1,604,979
Ensembl chrNW_004955528:1,595,231...1,604,979
JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chrNW_004955407:12,593,911...13,485,723
Ensembl chrNW_004955407:13,107,235...13,487,053
JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO (MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:5913048 NCBI chrNW_004955407:14,301,689...15,549,561
Ensembl chrNW_004955407:14,305,498...14,842,790
JBrowse link
regulation of heart induction by regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) BHF-UCL PMID:19736317 NCBI chrNW_004955583:995,707...1,003,202 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12096
    developmental process 5735
      developmental induction 41
        organ induction 28
          heart induction 10
            Notch signaling pathway involved in heart induction + 3
            endodermal-mesodermal cell signaling involved in heart induction + 3
            fibroblast growth factor receptor signaling pathway involved in heart induction 0
            mesodermal-endodermal cell signaling involved in heart induction 0
            negative regulation of heart induction + 1
            positive regulation of heart induction + 3
            regulation of heart induction + 5
Path 2
Term Annotations click to browse term
  biological_process 12096
    developmental process 5735
      anatomical structure development 5360
        multicellular organism development 4908
          system development 4605
            animal organ development 3556
              animal organ morphogenesis 1033
                animal organ formation 74
                  regulation of animal organ formation 33
                    organ induction 28
                      heart induction 10
                        Notch signaling pathway involved in heart induction + 3
                        endodermal-mesodermal cell signaling involved in heart induction + 3
                        fibroblast growth factor receptor signaling pathway involved in heart induction 0
                        mesodermal-endodermal cell signaling involved in heart induction 0
                        negative regulation of heart induction + 1
                        positive regulation of heart induction + 3
                        regulation of heart induction + 5
paths to the root