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ONTOLOGY REPORT - ANNOTATIONS


Term:cyclin K-CDK12 complex
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Accession:GO:0002944 term browser browse the term
Definition:A protein complex consisting of cyclin Kand cyclin-dependent kinase 12 (CDK12). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
Synonyms:related_synonym: CycK/Cdk12 complex



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cyclin K-CDK12 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnk cyclin K part_of ISO UniProtKB:Q9NYV4 (PMID:22012619) RGD PMID:22012619 NCBI chr 6:127,090,115...127,113,195
Ensembl chr 6:127,090,569...127,113,191
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G Cdk12 cyclin-dependent kinase 12 part_of ISO UniProtKB:O75909 (PMID:22012619) RGD PMID:22012619 NCBI chr10:83,201,177...83,256,906
Ensembl chr10:83,201,211...83,280,888
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  cellular_component 20016
    protein-containing complex 6014
      catalytic complex 1464
        transferase complex 801
          transferase complex, transferring phosphorus-containing groups 259
            protein kinase complex 104
              serine/threonine protein kinase complex 86
                cyclin-dependent protein kinase holoenzyme complex 44
                  cyclin K-CDK12 complex 2
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