Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:response to ischemia
go back to main search page
Accession:GO:0002931 term browser browse the term
Definition:Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.
Comment:Ischemia always results in hypoxia; however, hypoxia can occur without ischemia.



show annotations for term's descendants           Sort by:
 
response to ischemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas2 abraxas 2, BRISC complex subunit involved_in ISO (PMID:21195082)
(MGI:5700295|PMID:21195082)
RGD PMID:21195082 MGI:5700295 NCBI chr 1:187,647,078...187,672,660
Ensembl chr 1:187,647,067...187,672,655
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 NOT IEP RGD PMID:15181376 PMID:23685150 RGD:10047403, RGD:10053560 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akt1 AKT serine/threonine kinase 1 IEP RGD PMID:24601882 RGD:39128160 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IEP RGD PMID:30131474 RGD:15036798 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Arid1b AT-rich interaction domain 1B IEP RGD PMID:14633620 RGD:1302474 NCBI chr 1:45,567,991...45,923,644
Ensembl chr 1:45,563,623...45,923,493
JBrowse link
G Bax BCL2 associated X, apoptosis regulator IDA RGD PMID:31583047 RGD:155230831 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within ISO
IDA
MGI:1857430 (MGI:1351727|PMID:10488913) RGD PMID:10488913 PMID:31583047 MGI:1351727, RGD:155230831 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 IDA RGD PMID:21410437 RGD:7349317 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l2 Bcl2-like 2 IEP RGD PMID:10724126 RGD:14394498 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Bid BH3 interacting domain death agonist IEP RGD PMID:11934844 RGD:13782263 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bves blood vessel epicardial substance involved_in ISS
ISO
GO_REF:0000024
(MGI:5550350|PMID:24066022)
UniProt
RGD
PMID:24066022 GO_REF:0000024 MGI:5550350 NCBI chr20:48,819,241...48,860,282
Ensembl chr20:48,822,308...48,857,472
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:5444772|PMID:23051746)
ParkinsonsUK-UCL
RGD
PMID:23051746 GO_REF:0000024 MGI:5444772 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Casp9 caspase 9 IEP RGD PMID:11934844 RGD:13782263 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Casr calcium-sensing receptor IEP RGD PMID:21488219 RGD:7205700 NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811
JBrowse link
G Cav1 caveolin 1 acts_upstream_of_or_within ISO MGI:2180372 (MGI:3783955|PMID:17293479) RGD PMID:17293479 MGI:3783955 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cav3 caveolin 3 IEP RGD PMID:29438664 RGD:126925221 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3818804|PMID:17975111)
UniProt
RGD
PMID:17975111 GO_REF:0000024 MGI:3818804 NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423
JBrowse link
G Cpeb4 cytoplasmic polyadenylation element binding protein 4 involved_in ISO (MGI:5520043|PMID:20937770) RGD PMID:20937770 MGI:5520043 NCBI chr10:15,717,794...15,780,482
Ensembl chr10:15,717,794...15,780,603
JBrowse link
G Crebbp CREB binding protein IDA RGD PMID:24338162 RGD:153352322 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Csf1 colony stimulating factor 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:8922060)
Ensembl
RGD
PMID:8922060 GO_REF:0000107 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in IEA
ISO
GO_REF:0000107
(MGI:6275569|PMID:8922060)
Ensembl
RGD
PMID:8922060 GO_REF:0000107 MGI:6275569 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in IGI PMID:12059974 ARUK-UCL PMID:12059974 RGD:13673875 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IGI PMID:12059974 ARUK-UCL PMID:12059974 RGD:13673875 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Cycs cytochrome c, somatic IDA RGD PMID:21410437 RGD:7349317 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 IEP RGD PMID:15211596 RGD:10401223 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase IEP RGD PMID:12920134 RGD:10401252 NCBI chr 1:175,393,119...175,454,452
Ensembl chr 1:175,393,154...175,455,164
JBrowse link
G Egr1 early growth response 1 involved_in IEA
IDA
ISO
GO_REF:0000107
PMID:1859855
(MGI:1928025|PMID:11100120)
Ensembl
RGD
PMID:11100120 PMID:1859855 GO_REF:0000107 MGI:1928025, RGD:11535086 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 IEP RGD PMID:20736160 RGD:7242945 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:4888719 (MGI:4880811|PMID:21209208)
GO_REF:0000107
RGD
Ensembl
PMID:21209208 GO_REF:0000107 MGI:4880811 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168
JBrowse link
G Fas Fas cell surface death receptor IEP RGD PMID:30301943 RGD:153297779 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 IEP RGD PMID:10521571 RGD:10402090 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fn1 fibronectin 1 IEP RGD PMID:12482021 RGD:7205472 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Gja1 gap junction protein, alpha 1 involved_in IEP
ISO
(PMID:15919068) RGD PMID:15919068 PMID:24728265 RGD:11568671 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gjb2 gap junction protein, beta 2 IEP RGD PMID:24728265 RGD:11568671 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
JBrowse link
G Glrx glutaredoxin IEP RGD PMID:19938943 RGD:9686063 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
JBrowse link
G Gpr31 G protein-coupled receptor 31 involved_in ISO (MGI:6377747|PMID:29227475) RGD PMID:29227475 MGI:6377747 NCBI chr 1:52,926,953...52,927,912 JBrowse link
G Gsr glutathione-disulfide reductase IEP RGD PMID:9434704 RGD:11059511 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hk1 hexokinase 1 IDA RGD PMID:21410437 RGD:7349317 NCBI chr20:30,230,488...30,332,161
Ensembl chr20:30,230,486...30,332,131
JBrowse link
G Hk2 hexokinase 2 IDA RGD PMID:21410437 RGD:7349317 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B IEP RGD PMID:22526757 RGD:7257595 NCBI chr20:3,870,765...3,873,221 JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IEP RGD PMID:10559386 RGD:10402577 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEP RGD PMID:23447644 RGD:10402845 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Hyou1 hypoxia up-regulated 1 acts_upstream_of_or_within
involved_in
ISO (MGI:1320999|PMID:9748521)
(MGI:1931743|PMID:11231630)
RGD PMID:9748521 PMID:11231630 MGI:1320999 MGI:1931743 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 IEP RGD PMID:20971764 RGD:7296940 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 IEP RGD PMID:20550965 RGD:7243113 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 IEP RGD PMID:20550965 RGD:7243113 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 IEP RGD PMID:20550965 RGD:7243113 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in IDA PMID:19103177 Alzheimers_University_of_Toronto PMID:19103177 RGD:8554846 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mir143 microRNA 143 IEP RGD PMID:28859292 RGD:152025219 NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110
JBrowse link
G Mir145 microRNA 145 IDA RGD PMID:23166305 PMID:31583047 RGD:155230822, RGD:155230831 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Mir195 microRNA 195 involved_in ISO (PMID:30497184) RGD PMID:30497184 NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924
JBrowse link
G Mir210 microRNA 210 IDA RGD PMID:34337881 RGD:155269103 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link
G Mir222 microRNA 222 IEP RGD PMID:28859292 RGD:152025219 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006
JBrowse link
G Mlycd malonyl-CoA decarboxylase involved_in IMP PMID:15105298 UniProt PMID:15105298 RGD:1600796 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
JBrowse link
G Ndnf neuron-derived neurotrophic factor involved_in ISO (MGI:5607385|PMID:24706764) RGD PMID:24706764 MGI:5607385 NCBI chr 4:94,944,749...94,987,414
Ensembl chr 4:94,944,360...94,981,873
JBrowse link
G Nol3 nucleolar protein 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:3710289|PMID:16505176)
Ensembl
RGD
PMID:16505176 GO_REF:0000107 MGI:3710289 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Nppc natriuretic peptide C involved_in ISO MGI:5660304 (MGI:6363863|PMID:30586761) RGD PMID:30586761 MGI:6363863 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
JBrowse link
G Npr3 natriuretic peptide receptor 3 involved_in ISO (MGI:6363863|PMID:30586761) RGD PMID:30586761 MGI:6363863 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 IEP RGD PMID:31399183 RGD:25823190 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G P2rx2 purinergic receptor P2X 2 involved_in IMP PMID:12849743 ARUK-UCL PMID:12849743 RGD:13673769 NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891
JBrowse link
G P2rx4 purinergic receptor P2X 4 involved_in IMP PMID:12849743 ARUK-UCL PMID:12849743 RGD:13673769 NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253
JBrowse link
G Panx1 Pannexin 1 acts_upstream_of_or_within ISO MGI:1890615 (MGI:5306522|PMID:22147915) RGD PMID:22147915 MGI:5306522 NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774
JBrowse link
G Panx2 pannexin 2 acts_upstream_of_or_within ISO MGI:1860055 (MGI:5306522|PMID:22147915) RGD PMID:22147915 MGI:5306522 NCBI chr 7:120,139,259...120,153,056
Ensembl chr 7:120,139,294...120,152,361
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 IEP RGD PMID:12872233 RGD:1624250 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Per2 period circadian regulator 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5546525|PMID:23977055)
UniProt
RGD
PMID:23977055 GO_REF:0000024 MGI:5546525 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta involved_in IEA
ISO
GO_REF:0000107
(MGI:6444553|PMID:30496354)
Ensembl
RGD
PMID:30496354 GO_REF:0000107 MGI:6444553 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Pink1 PTEN induced kinase 1 IEP RGD PMID:25791474 RGD:12903964 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IEP RGD PMID:21302669 RGD:10059656 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppif peptidylprolyl isomerase F involved_in ISS
ISO
GO_REF:0000024
(MGI:3576003|PMID:15800626), (MGI:3603054|PMID:16103352)
UniProt
RGD
PMID:15800626 PMID:16103352 GO_REF:0000024 MGI:3576003 MGI:3603054 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in IMP PMID:15814199 Alzheimers_University_of_Toronto PMID:15814199 RGD:8655534 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Rcan1 regulator of calcineurin 1 acts_upstream_of_or_within ISO MGI:3641540 (MGI:3629336|PMID:16648267) RGD PMID:16648267 MGI:3629336 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IDA RGD PMID:31583047 RGD:155230831 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rest RE1-silencing transcription factor involved_in IDA
IEP
PMID:22371606
PMID:25108103
PMID:12657670
UniProt PMID:22371606 PMID:25108103 PMID:12657670 RGD:14397566, RGD:14397584, RGD:1299303 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase IEP RGD PMID:21297953 RGD:7327162 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO (MGI:6271078|PMID:29353861) RGD PMID:29353861 MGI:6271078 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
JBrowse link
G Sirt5 sirtuin 5 acts_upstream_of_or_within ISO MGI:5297911 (MGI:6101519|PMID:26388266) RGD PMID:26388266 MGI:6101519 NCBI chr17:21,310,028...21,337,137
Ensembl chr17:21,310,028...21,337,101
JBrowse link
G Slc26a5 solute carrier family 26 member 5 IEP RGD PMID:15925203 RGD:9479072 NCBI chr 4:13,210,260...13,249,289
Ensembl chr 4:13,210,260...13,249,289
JBrowse link
G Slc8a2 solute carrier family 8 member A2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3796351|PMID:17884163)
Ensembl
RGD
PMID:17884163 GO_REF:0000107 MGI:3796351 NCBI chr 1:76,816,583...76,852,928
Ensembl chr 1:76,808,725...76,847,072
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 IDA RGD PMID:26442853 RGD:155630597 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107
JBrowse link
G Sqstm1 sequestosome 1 IEP RGD PMID:23782269 RGD:13210581 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in IDA PMID:19953350 ARUK-UCL PMID:19953350 RGD:13507303 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in ISO (MGI:5574521|PMID:24872551) RGD PMID:24872551 MGI:5574521 NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:1857263 (MGI:5319065|PMID:22044588) RGD PMID:22044588 MGI:5319065 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Traf6 TNF receptor associated factor 6 IEP RGD PMID:27538408 RGD:151347179 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6294162|PMID:28592261) RGD PMID:28592261 MGI:6294162 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Ubd ubiquitin D IEP RGD PMID:29438664 RGD:126925221 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 acts_upstream_of_or_within ISO MGI:1856882 (MGI:3033270|PMID:14695319) RGD PMID:14695319 MGI:3033270 NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19874
    response to stimulus 10557
      response to stress 4278
        response to ischemia 87
paths to the root