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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of humoral immune response
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Accession:GO:0002921 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.
Synonyms:exact_synonym: down regulation of humoral immune response;   downregulation of humoral immune response
 narrow_synonym: inhibition of humoral immune response


show annotations for term's descendants           Sort by:
negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59b CD59b molecule acts_upstream_of_or_within
involved_in 		IDA
ISO
IEA
IBA 		(PMID:10946279), (PMID:11471050)
(PMID:11882685), (PMID:1698710), (PMID:36797260)
GO_REF:0000117
GO_REF:0000033 		RGD
UniProt
GO_Central		 PMID:1698710 PMID:10946279 PMID:11471050 PMID:11882685 PMID:36797260 More... GO_REF:0000033 GO_REF:0000117, RGD:1600482 NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:110,914,091...110,935,310 		JBrowse link
G Clu clusterin involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:34667172), (PMID:9200695) 		UniProt
Ensembl
RGD		 PMID:9200695 PMID:34667172 GO_REF:0000024 GO_REF:0000107 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860 		JBrowse link
G LOC134480016 urinary protein 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:43,339,749...43,343,430 JBrowse link
G Rup2l2 urinary protein 2 like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:43,961,640...43,965,241
Ensembl chr 8:43,961,640...43,965,241 		JBrowse link
negative regulation of antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink5 serine peptidase inhibitor, Kazal type 5 involved_in ISO (PMID:17012259) RGD PMID:17012259 NCBI chr18:36,515,347...36,584,038
Ensembl chr18:36,515,347...36,583,799 		JBrowse link
negative regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink5 serine peptidase inhibitor, Kazal type 5 involved_in IEA
ISO 		GO_REF:0000107
(PMID:17012259) 		Ensembl
RGD		 PMID:17012259 GO_REF:0000107 NCBI chr18:36,515,347...36,584,038
Ensembl chr18:36,515,347...36,583,799 		JBrowse link
negative regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr13:109,104,122...109,134,903 JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in IDA
ISO 		(PMID:28657829), (PMID:6211481) RGD PMID:6211481 PMID:28657829 PMID:10929073 RGD:2326180 NCBI chr13:44,409,574...44,438,913
Ensembl chr13:44,409,587...44,438,107 		JBrowse link
G Cd59b CD59b molecule involved_in
acts_upstream_of_or_within 		ISO (PMID:11882685), (PMID:1698710), (PMID:36797260)
(PMID:10946279) 		RGD PMID:1698710 PMID:10946279 PMID:11882685 PMID:36797260 NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:110,914,091...110,935,310 		JBrowse link
G Clu clusterin involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:34667172), (PMID:9200695) 		UniProt
Ensembl
RGD		 PMID:9200695 PMID:34667172 GO_REF:0000024 GO_REF:0000107 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860 		JBrowse link
G Cr1l complement C3b/C4b receptor 1 like acts_upstream_of_or_within
involved_in 		IMP
ISO
IEA 		MGI:2158683 (PMID:10642554)
GO_REF:0000117 		RGD
UniProt		 PMID:10642554 PMID:11861390 GO_REF:0000117, RGD:625470 NCBI chr13:109,138,132...109,189,068
Ensembl chr13:109,103,235...109,188,869 		JBrowse link
G Cr2 complement C3d receptor 2 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr13:109,207,034...109,244,980
Ensembl chr13:109,213,867...109,244,552 		JBrowse link
G Masp1 MBL associated serine protease 1 involved_in ISO (PMID:11485744) RGD PMID:11485744 NCBI chr11:90,839,081...90,909,922
Ensembl chr11:90,839,061...90,917,470 		JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) RGD PMID:9029106 NCBI chr13:109,104,122...109,134,903 JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO (PMID:23482636) RGD PMID:23482636 NCBI chr13:96,982,867...97,109,419
Ensembl chr13:96,986,788...97,109,401 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 involved_in ISO
IBA 		UniProtKB:P01024 (PMID:17051150)
GO_REF:0000033 		RGD
GO_Central		 PMID:17051150 GO_REF:0000033 NCBI chr  X:65,154,422...65,179,708
Ensembl chr  X:65,154,424...65,179,708 		JBrowse link
negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4bpa complement component 4 binding protein, alpha involved_in ISO
IEA
IBA 		(PMID:22333221)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:22333221 GO_REF:0000033 GO_REF:0000107 NCBI chr13:44,627,959...44,663,552
Ensembl chr13:44,627,982...44,663,471 		JBrowse link
G C4bpb complement component 4 binding protein, beta involved_in ISO
IEA 		(PMID:22333221)
GO_REF:0000107 		RGD
Ensembl		 PMID:22333221 GO_REF:0000107 NCBI chr13:44,673,064...44,683,781
Ensembl chr13:44,673,065...44,683,793 		JBrowse link
G Cd46 CD46 molecule involved_in ISO
IBA 		(PMID:9029106)
GO_REF:0000033 		RGD
GO_Central		 PMID:9029106 GO_REF:0000033 NCBI chr13:109,104,122...109,134,903 JBrowse link
G Cd46l1 CD46 molecule like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:34,538,996...34,539,997
Ensembl chr20:34,538,816...34,540,027 		JBrowse link
G Cr1l complement C3b/C4b receptor 1 like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:109,138,132...109,189,068
Ensembl chr13:109,103,235...109,188,869 		JBrowse link
G Cr2 complement C3d receptor 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:109,207,034...109,244,980
Ensembl chr13:109,213,867...109,244,552 		JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO (PMID:23482636) RGD PMID:23482636 NCBI chr13:96,982,867...97,109,419
Ensembl chr13:96,986,788...97,109,401 		JBrowse link
G Zp3r zona pellucida 3 receptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:44,572,283...44,617,101
Ensembl chr13:44,572,283...44,617,077 		JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin involved_in ISO (PMID:12538697) RGD PMID:12538697 NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868 		JBrowse link
G Serping1 serpin family G member 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:10946292) 		UniProt
Ensembl
RGD		 PMID:10946292 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717 		JBrowse link
negative regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxj1 forkhead box J1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:16002694) 		Ensembl
RGD		 PMID:16002694 GO_REF:0000107 NCBI chr10:102,065,163...102,069,945
Ensembl chr10:102,065,170...102,069,241 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1856074 (PMID:9254656) 		Ensembl
RGD		 PMID:9254656 GO_REF:0000107 NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:159,212,320...159,237,069 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    immune system process 2920
      immune response 2015
        negative regulation of immune response 222
          negative regulation of humoral immune response 20
            negative regulation of antimicrobial humoral response + 1
            negative regulation of complement activation + 17
            negative regulation of humoral immune response mediated by circulating immunoglobulin + 10
Path 2
Term Annotations click to browse term
  biological_process 19315
    biological regulation 13355
      regulation of biological process 12936
        negative regulation of biological process 5902
          negative regulation of immune system process 595
            negative regulation of immune response 222
              negative regulation of humoral immune response 20
                negative regulation of antimicrobial humoral response + 1
                negative regulation of complement activation + 17
                negative regulation of humoral immune response mediated by circulating immunoglobulin + 10
paths to the root