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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of response to biotic stimulus
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Accession:GO:0002832 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.
Comment:Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
Synonyms:exact_synonym: down regulation of response to biotic stimulus;   downregulation of response to biotic stimulus
 narrow_synonym: inhibition of response to biotic stimulus


show annotations for term's descendants           Sort by:
negative regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink5 serine peptidase inhibitor, Kazal type 5 involved_in ISO (MGI:3770082|PMID:17012259) RGD PMID:17012259 MGI:3770082 NCBI chr18:36,264,452...36,333,143
Ensembl chr18:36,264,452...36,332,185 		JBrowse link
negative regulation of antifungal innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fam3a FAM3 metabolism regulating signaling molecule A involved_in ISO (PMID:18212107) RGD PMID:18212107 NCBI chr  X:152,166,716...152,175,327
Ensembl chr  X:152,165,535...152,175,362 		JBrowse link
G Usp15 ubiquitin specific peptidase 15 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:33093067)		 Ensembl
UniProt
RGD		 PMID:33093067 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721 		JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) RGD PMID:9029106 NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445 		JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO
IBA		 (PMID:23482636)
PMID:21873635		 RGD PMID:23482636 PMID:21873635 RGD:13792537 NCBI chr13:94,455,180...94,577,773
Ensembl chr13:94,455,165...94,577,750 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 involved_in IBA
ISO		 PMID:21873635
UniProtKB:P01024 (PMID:17051150)		 RGD PMID:17051150 PMID:21873635 RGD:13792537 NCBI chr  X:61,144,926...61,170,212
Ensembl chr  X:61,144,928...61,170,212 		JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin involved_in ISO (PMID:12538697) RGD PMID:12538697 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Serping1 serpin family G member 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10946292)		 UniProt
RGD		 PMID:10946292 GO_REF:0000024 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034 		JBrowse link
negative regulation of defense response to bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5908771|PMID:27074721)		 Ensembl
RGD		 PMID:27074721 GO_REF:0000107 MGI:5908771 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) RGD PMID:22842346 MGI:5437532 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Mapkbp1 mitogen activated protein kinase binding protein 1 involved_in ISO (PMID:22700971) RGD PMID:22700971 NCBI chr 3:106,947,342...106,998,368
Ensembl chr 3:106,947,827...106,996,199 		JBrowse link
G Mir181b1 microRNA 181b-1 involved_in ISO ENSEMBL_GeneID:ENSG00000171049 (PMID:25505240) RGD PMID:25505240 NCBI chr13:49,485,688...49,485,797
Ensembl chr13:49,485,688...49,485,797 		JBrowse link
G Mir181b2 microRNA 181b-2 involved_in ISO ENSEMBL_GeneID:ENSG00000171049 (PMID:25505240) RGD PMID:25505240 NCBI chr 3:22,616,948...22,617,035
Ensembl chr 3:22,616,948...22,617,035 		JBrowse link
G Pten phosphatase and tensin homolog IMP RGD PMID:18056380 RGD:2292524 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
negative regulation of defense response to virus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg12 autophagy related 12 involved_in ISO (PMID:19666601)
(MGI:3722754|PMID:17709747)		 RGD PMID:17709747 PMID:19666601 MGI:3722754 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418 		JBrowse link
G Atg5 autophagy related 5 involved_in ISO
IEA		 (PMID:19666601)
(MGI:3722754|PMID:17709747)
GO_REF:0000107		 RGD
Ensembl		 PMID:17709747 PMID:19666601 GO_REF:0000107 MGI:3722754 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G C1qbp complement C1q binding protein involved_in ISO
ISS		 (PMID:19164550)
GO_REF:0000024		 RGD
UniProt		 PMID:19164550 GO_REF:0000024 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649 		JBrowse link
G Fgl2 fibrinogen-like 2 acts_upstream_of_or_within ISO MGI:3582343 (MGI:6188369|PMID:29341118) RGD PMID:29341118 MGI:6188369 NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207 		JBrowse link
G Foxp3 forkhead box P3 IMP RGD PMID:17878294 RGD:2325989 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Htra1 HtrA serine peptidase 1 IMP RGD PMID:15333144 RGD:2311622 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Ilrun inflammation and lipid regulator with UBA-like and NBR1-like domains involved_in ISO (PMID:29802199) RGD PMID:29802199 NCBI chr20:5,809,931...5,876,197
Ensembl chr20:5,809,936...5,876,012 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
ISO		 GO_REF:0000024
(MGI:6810721|PMID:34467632)
(PMID:34467632), (PMID:36221902)		 UniProt
RGD		 PMID:34467632 PMID:36221902 GO_REF:0000024 MGI:6810721 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Itch itchy E3 ubiquitin protein ligase involved_in ISO (PMID:19881509)
(MGI:4436832|PMID:19881509)		 RGD PMID:19881509 MGI:4436832 NCBI chr 3:143,642,348...143,733,745
Ensembl chr 3:143,645,637...143,733,543 		JBrowse link
G Mir26b microRNA 26b involved_in ISO (PMID:26222045) RGD PMID:26222045 NCBI chr 9:75,976,596...75,976,680
Ensembl chr 9:75,976,596...75,976,680 		JBrowse link
G Pcbp2 poly(rC) binding protein 2 involved_in ISO (PMID:19881509) RGD PMID:19881509 NCBI chr 7:133,605,375...133,631,312
Ensembl chr 7:133,605,573...133,629,863 		JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B involved_in ISO
IEA
ISS		 (PMID:22750291)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:22750291 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974 		JBrowse link
G Rnf26 ring finger protein 26 involved_in ISO (PMID:25254379) RGD PMID:25254379 NCBI chr 8:44,454,551...44,456,745
Ensembl chr 8:44,454,292...44,457,331 		JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:22079989)
(MGI:5306204|PMID:22079989)
GO_REF:0000107		 RGD
Ensembl		 PMID:22079989 GO_REF:0000107 MGI:5306204 NCBI chr 9:92,073,622...92,110,427
Ensembl chr 9:92,073,640...92,108,977 		JBrowse link
G Trim38 tripartite motif containing 38 acts_upstream_of_or_within ISO (MGI:5441682|PMID:22539786) RGD PMID:22539786 MGI:5441682 NCBI chr17:41,351,857...41,365,021 JBrowse link
negative regulation of defense response to virus by host term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf3 interferon regulatory factor 3 acts_upstream_of_or_within ISO (MGI:3828224|PMID:18851954) RGD PMID:18851954 MGI:3828224 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:23399697) RGD PMID:23399697 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II involved_in ISO (PMID:36159777) RGD PMID:36159777 NCBI chr 1:245,770,993...245,896,925
Ensembl chr 1:245,772,277...245,897,913 		JBrowse link
G Tarbp2 Tarbp2 subunit of RISC loading complex involved_in ISO
ISS		 (PMID:11641396)
GO_REF:0000024		 RGD
UniProt		 PMID:11641396 GO_REF:0000024 NCBI chr 7:133,649,118...133,654,306
Ensembl chr 7:133,649,090...133,654,314 		JBrowse link
negative regulation of immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) RGD PMID:22842346 MGI:5437532 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
negative regulation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (MGI:5490396|PMID:23609450) RGD PMID:23609450 MGI:5490396 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Atg12 autophagy related 12 involved_in ISO (MGI:3722754|PMID:17709747) RGD PMID:17709747 MGI:3722754 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418 		JBrowse link
G Atg5 autophagy related 5 involved_in ISO
IEA		 (MGI:3722754|PMID:17709747)
GO_REF:0000107		 RGD
Ensembl		 PMID:17709747 GO_REF:0000107 MGI:3722754 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Aurkb aurora kinase B involved_in ISO
IEA		 (PMID:33542149)
GO_REF:0000107		 RGD
Ensembl		 PMID:33542149 GO_REF:0000107 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Banf1 BAF nuclear assembly factor 1 involved_in ISO (PMID:32792394) RGD PMID:32792394 NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 involved_in ISO (MGI:4943412|PMID:15557190) RGD PMID:15557190 MGI:4943412 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Cep63 centrosomal protein 63 involved_in ISO
IEA		 (PMID:35793002)
GO_REF:0000107		 RGD
Ensembl		 PMID:35793002 GO_REF:0000107 NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO (PMID:21525357)
(MGI:5318004|PMID:21525357)		 RGD PMID:21525357 MGI:5318004 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Drd2 dopamine receptor D2 involved_in ISO (MGI:5473736|PMID:23242137) RGD PMID:23242137 MGI:5473736 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 involved_in ISO (PMID:27692986), (PMID:35793002) RGD PMID:27692986 PMID:35793002 NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818 		JBrowse link
G Grn granulin precursor involved_in ISS
ISO		 GO_REF:0000024
(MGI:4421471|PMID:20026663)		 UniProt
RGD		 PMID:20026663 GO_REF:0000024 MGI:4421471 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) RGD PMID:22842346 MGI:5437532 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO (MGI:2183694|PMID:12150927) RGD PMID:12150927 MGI:2183694 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Lyar Ly1 antibody reactive involved_in IEA
ISO		 GO_REF:0000107
(PMID:31413131)		 Ensembl
RGD		 PMID:31413131 GO_REF:0000107 NCBI chr14:72,576,878...72,590,854
Ensembl chr14:72,576,879...72,590,612 		JBrowse link
G Mir181b1 microRNA 181b-1 involved_in ISO ENSEMBL_GeneID:ENSG00000171049 (PMID:25505240) RGD PMID:25505240 NCBI chr13:49,485,688...49,485,797
Ensembl chr13:49,485,688...49,485,797 		JBrowse link
G Mir181b2 microRNA 181b-2 involved_in ISO ENSEMBL_GeneID:ENSG00000171049 (PMID:25505240) RGD PMID:25505240 NCBI chr 3:22,616,948...22,617,035
Ensembl chr 3:22,616,948...22,617,035 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:22286305) RGD PMID:22286305 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:23399697) RGD PMID:23399697 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO (MGI:5568884|PMID:24560620) RGD PMID:24560620 MGI:5568884 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398 		JBrowse link
G Nlrp4 NLR family, pyrin domain containing 4 involved_in ISO (PMID:27692986) RGD PMID:27692986 NCBI chr 1:68,089,321...68,132,429
Ensembl chr 1:68,089,321...68,127,521 		JBrowse link
G Nlrx1 NLR family member X1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5141085 (MGI:5050761|PMID:21703540)		 Ensembl
RGD		 PMID:21703540 GO_REF:0000107 MGI:5050761 NCBI chr 8:44,588,476...44,606,678
Ensembl chr 8:44,590,048...44,606,484 		JBrowse link
G Nmi N-myc (and STAT) interactor involved_in
acts_upstream_of_or_within		 ISO (PMID:26342464)
(MGI:5546557|PMID:23956435)		 RGD PMID:23956435 PMID:26342464 MGI:5546557 NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:32844745), (PMID:35460603)
(MGI:7286108|PMID:35460603)		 UniProt
RGD		 PMID:32844745 PMID:35460603 GO_REF:0000024 MGI:7286108 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (MGI:5490396|PMID:23609450) RGD PMID:23609450 MGI:5490396 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 involved_in ISS
IBA
ISO
IEA		 GO_REF:0000024
PMID:21873635
(MGI:3831253|PMID:18849341)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18849341 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:3831253, RGD:13792537 NCBI chr12:35,165,606...35,179,525
Ensembl chr12:35,165,606...35,179,525 		JBrowse link
G Trex1 three prime repair exonuclease 1 involved_in ISO (PMID:33476576) RGD PMID:33476576 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Trim21 tripartite motif-containing 21 involved_in ISO (PMID:26342464) RGD PMID:26342464 NCBI chr 1:156,964,896...156,987,504
Ensembl chr 1:156,964,913...156,987,440 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
UniProtKB:Q00993|UniProtKB:Q60805 (MGI:3773763|PMID:18083102)		 UniProt
Ensembl
RGD		 PMID:18083102 GO_REF:0000024 GO_REF:0000107 MGI:3773763 NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142 		JBrowse link
G Usp38 ubiquitin specific peptidase 38 involved_in ISO (PMID:27692986) RGD PMID:27692986 NCBI chr19:27,006,046...27,037,449
Ensembl chr19:27,006,046...27,037,437 		JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta involved_in ISO (PMID:35662396) RGD PMID:35662396 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668 		JBrowse link
G Zdhhc18 zinc finger DHHC-type palmitoyltransferase 18 involved_in ISO
IEA
ISS		 (PMID:35438208)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:35438208 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:145,821,534...145,859,989
Ensembl chr 5:145,831,446...145,859,993 		JBrowse link
negative regulation of lipopolysaccharide-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) RGD PMID:20829348 NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829 		JBrowse link
G Defb21 defensin beta 21 involved_in ISO (PMID:33181266) RGD PMID:33181266 NCBI chr 3:141,042,810...141,044,228
Ensembl chr 3:141,042,810...141,044,184 		JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) RGD PMID:20345905 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Nfkbil1 NFKB inhibitor like 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20829348)		 UniProt
RGD		 PMID:20829348 GO_REF:0000024 NCBI chr20:3,589,974...3,608,348
Ensembl chr20:3,590,642...3,605,616 		JBrowse link
G Prdm1 PR/SET domain 1 acts_upstream_of_or_within ISO (MGI:3826899|PMID:18845144) RGD PMID:18845144 MGI:3826899 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Prdx2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2668456 (MGI:3758374|PMID:17325201)		 Ensembl
RGD		 PMID:17325201 GO_REF:0000107 MGI:3758374 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in ISO (PMID:17452330) RGD PMID:17452330 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd96 CD96 molecule acts_upstream_of_or_within ISO MGI:5617136 (MGI:5569209|PMID:24658051) RGD PMID:24658051 MGI:5569209 NCBI chr11:54,702,290...54,776,618
Ensembl chr11:54,702,290...54,776,621 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (MGI:5491117|PMID:23408620) RGD PMID:23408620 MGI:5491117 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 involved_in ISO
IEA		 (PMID:18604210)
GO_REF:0000107		 RGD
Ensembl		 PMID:18604210 GO_REF:0000107 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Clec12b C-type lectin domain family 12, member B involved_in ISO (PMID:17562706) RGD PMID:17562706 NCBI chr 4:162,827,462...162,843,821
Ensembl chr 4:162,827,462...162,838,946 		JBrowse link
G Crk CRK proto-oncogene, adaptor protein IMP RGD PMID:18835194 RGD:11568650 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration IDA RGD PMID:9021955 RGD:9685777 NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869 		JBrowse link
G Igf2 insulin-like growth factor 2 IDA RGD PMID:9021955 RGD:9685777 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in ISO (PMID:9485206), (PMID:9486650) RGD PMID:9485206 PMID:9486650 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425 		JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
IEA
ISS		 (PMID:9486650)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:9486650 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:20068167) RGD PMID:20068167 NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930 		JBrowse link
G RT1-A1 RT1 class Ia, locus A1 IMP RGD PMID:10837412 RGD:2313500 NCBI chr20:4,905,309...4,914,593 JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:10799855), (PMID:17179229), (PMID:23335510), (PMID:9486650) RGD PMID:9486650 PMID:10799855 PMID:17179229 PMID:23335510 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:10190900), (PMID:12874224) RGD PMID:10190900 PMID:12874224 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Sh2d1b2 SH2 domain containing 1B2 acts_upstream_of_or_within ISO MGI:3641175 (MGI:3639618|PMID:16127454) RGD PMID:16127454 MGI:3639618 NCBI chr13:82,437,418...82,461,511
Ensembl chr13:82,437,428...82,461,509 		JBrowse link
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS		 (PMID:23696226)
(MGI:5512785|PMID:23696226)
GO_REF:0000024		 RGD
UniProt		 PMID:23696226 GO_REF:0000024 MGI:5512785 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) RGD PMID:22842346 MGI:5437532 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Klre1 killer cell lectin like receptor E1 IDA RGD PMID:12782717 RGD:1299590 NCBI chr 4:163,033,581...163,041,641
Ensembl chr 4:163,033,563...163,041,638 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:24586048) RGD PMID:24586048 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
negative regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dusp10 dual specificity phosphatase 10 acts_upstream_of_or_within ISO MGI:3052343 (MGI:4366202|PMID:19696743) RGD PMID:19696743 MGI:4366202 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Grn granulin precursor involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:12526812)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:12526812 GO_REF:0000024 GO_REF:0000107 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:11443198) RGD PMID:11443198 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Rps19 ribosomal protein S19 involved_in ISO (PMID:15750715) RGD PMID:15750715 NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508 		JBrowse link
G Slamf8 SLAM family member 8 acts_upstream_of_or_within ISO MGI:5442794 (MGI:5752697|PMID:25799045) RGD PMID:25799045 MGI:5752697 NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211 		JBrowse link
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc4 mucin 4, cell surface associated IDA RGD PMID:10232613 RGD:2303754 NCBI chr11:68,008,245...68,053,242 JBrowse link
negative regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor involved_in ISO
IEA
ISS		 (PMID:32818467)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:32818467 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:32818467)
(MGI:6508501|PMID:21469114), (MGI:6508513|PMID:28405502)		 RGD PMID:21469114 PMID:28405502 PMID:32818467 MGI:6508501 MGI:6508513 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3828307 (MGI:3821394|PMID:19060901)
GO_REF:0000107		 RGD
Ensembl		 PMID:19060901 GO_REF:0000107 MGI:3821394 NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) RGD PMID:20829348 NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829 		JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 involved_in ISO (PMID:23386060) RGD PMID:23386060 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576 		JBrowse link
G Dcst1 DC-STAMP domain containing 1 involved_in ISO (PMID:27782195) RGD PMID:27782195 NCBI chr 2:174,765,203...174,784,023
Ensembl chr 2:174,765,350...174,781,806 		JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E family member 2 involved_in ISO (PMID:35878012) RGD PMID:35878012 NCBI chr 9:87,886,126...87,914,470
Ensembl chr 9:87,878,085...87,914,482 		JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 involved_in ISO (PMID:35878012) RGD PMID:35878012 NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier involved_in ISO (PMID:28724761) RGD PMID:28724761 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit involved_in ISO (PMID:30559377) RGD PMID:30559377 NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:23633945) RGD PMID:23633945 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5583923|PMID:24784232)		 Ensembl
RGD		 PMID:24784232 GO_REF:0000107 MGI:5583923 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:23399697) RGD PMID:23399697 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 involved_in ISO
IBA		 (PMID:20434986)
PMID:21873635
(MGI:4454346|PMID:20434986)		 RGD PMID:20434986 PMID:21873635 MGI:4454346, RGD:13792537 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO (PMID:30078389) RGD PMID:30078389 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in ISO
IEA		 (PMID:30078389)
GO_REF:0000107		 RGD
Ensembl		 PMID:30078389 GO_REF:0000107 NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
IEA
ISS		 (PMID:11909529)
GO_REF:0000107
(MGI:3691503|PMID:11909529), (MGI:5493216|PMID:12138178)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:11909529 PMID:12138178 GO_REF:0000024 GO_REF:0000107 MGI:3691503 MGI:5493216 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (PMID:29670289)
(MGI:5521417|PMID:23972988)		 RGD PMID:23972988 PMID:29670289 MGI:5521417 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386 		JBrowse link
G Stat2 signal transducer and activator of transcription 2 involved_in ISO (PMID:28165510)
(MGI:6508512|PMID:28165510)		 RGD PMID:28165510 MGI:6508512 NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (MGI:3834787|PMID:18724932) RGD PMID:18724932 MGI:3834787 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Ttll12 tubulin tyrosine ligase like 12 involved_in ISO (PMID:28011935) RGD PMID:28011935 NCBI chr 7:114,731,890...114,751,237
Ensembl chr 7:114,731,892...114,751,356 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 involved_in ISO (PMID:28165510) RGD PMID:28165510 NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144 		JBrowse link
G Ythdf2 YTH N6-methyladenosine RNA binding protein F2 involved_in ISO (PMID:30559377) RGD PMID:30559377 NCBI chr 5:144,381,426...144,407,126
Ensembl chr 5:144,381,431...144,408,144 		JBrowse link
G Ythdf3 YTH N6-methyladenosine RNA binding protein F3 involved_in ISO (MGI:6316470|PMID:30591559) RGD PMID:30591559 MGI:6316470 NCBI chr 2:98,350,304...98,384,608
Ensembl chr 2:98,350,588...98,384,606 		JBrowse link
negative regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO
IEA		 (PMID:16709924)
GO_REF:0000107		 RGD
Ensembl		 PMID:16709924 GO_REF:0000107 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:11679576) RGD PMID:11679576 NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161 		JBrowse link
G Otop1 otopetrin 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5750846|PMID:24379350)		 UniProt
RGD		 PMID:24379350 GO_REF:0000024 MGI:5750846 NCBI chr14:72,505,036...72,532,497
Ensembl chr14:72,503,592...72,532,497 		JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 involved_in ISO (PMID:27796300)
(MGI:5905929|PMID:27796300)		 RGD PMID:27796300 MGI:5905929 NCBI chr11:64,902,848...64,934,916
Ensembl chr11:64,902,785...64,934,916 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:21268089) RGD PMID:21268089 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5493216|PMID:12138178)		 UniProt
Ensembl
RGD		 PMID:12138178 GO_REF:0000024 GO_REF:0000107 MGI:5493216 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
protection from natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec2d C-type lectin domain family 2, member D acts_upstream_of_or_within ISO MGI:107539 (MGI:2682492|PMID:12858173), (MGI:3041277|PMID:14990792), (MGI:3849756|PMID:19535641) RGD PMID:12858173 PMID:14990792 PMID:19535641 MGI:2682492 MGI:3041277 MGI:3849756 NCBI chr 4:162,216,052...162,239,530
Ensembl chr 4:162,216,572...162,239,527 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:25631937), (PMID:9754572) RGD PMID:9754572 PMID:25631937 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE16 RT1 class I, locus CE16 NOT|involved_in ISO (PMID:18502829)
(PMID:18502829), (PMID:8839770)		 RGD PMID:8839770 PMID:18502829 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:11290782) RGD PMID:11290782 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Serpinb3a serpin family B member 3A involved_in ISO (PMID:21857942) RGD PMID:21857942 NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985 		JBrowse link
G Serpinb9 serpin family B member 9 involved_in ISO (PMID:21795594) RGD PMID:21795594 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member IMP RGD PMID:8120379 RGD:2312378 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member IMP RGD PMID:8120379 RGD:2312378 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407 		JBrowse link
tolerance induction to lipopolysaccharide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450)
(MGI:5490396|PMID:23609450)		 RGD PMID:23609450 MGI:5490396 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:21220427) RGD PMID:21220427 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    negative regulation of biological process 5673
      negative regulation of response to stimulus 1826
        negative regulation of response to biotic stimulus 119
          negative regulation of antimicrobial humoral response + 1
          negative regulation of defense response to bacterium + 7
          negative regulation of defense response to insect 0
          negative regulation of defense response to oomycetes 0
          negative regulation of defense response to virus + 19
          negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus 0
          negative regulation of innate immune response + 90
          negative regulation of lipopolysaccharide-mediated signaling pathway + 9
          negative regulation of neutrophil mediated killing of symbiont cell + 0
          negative regulation of response to tumor cell + 7
          negative regulation of systemic acquired resistance + 0
          negative regulation of xenophagy 0
Path 2
Term Annotations click to browse term
  biological_process 19553
    biological regulation 13187
      regulation of biological process 12813
        negative regulation of biological process 5673
          negative regulation of response to stimulus 1826
            negative regulation of response to biotic stimulus 119
              negative regulation of antimicrobial humoral response + 1
              negative regulation of defense response to bacterium + 7
              negative regulation of defense response to insect 0
              negative regulation of defense response to oomycetes 0
              negative regulation of defense response to virus + 19
              negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus 0
              negative regulation of innate immune response + 90
              negative regulation of lipopolysaccharide-mediated signaling pathway + 9
              negative regulation of neutrophil mediated killing of symbiont cell + 0
              negative regulation of response to tumor cell + 7
              negative regulation of systemic acquired resistance + 0
              negative regulation of xenophagy 0
paths to the root