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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of response to biotic stimulus
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Accession:GO:0002831 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.
Comment:Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.


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regulation of response to biotic stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NGFR nerve growth factor receptor ISO neurotrophin-induced cell death RGD PMID:12929129 RGD:5508773 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008 		JBrowse link
activation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIM2 absent in melanoma 2 involved_in IEA
IBA
IDA		 (PMID:19158675), (PMID:19158676), (PMID:19158679) Ensembl
GO_Central
UniProt
InterPro		 PMID:19158675 PMID:19158676 PMID:19158679 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:159,055,051...159,147,132
Ensembl chr 1:159,056,129...159,187,843 		JBrowse link
G CARD8 caspase recruitment domain family member 8 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:48,203,148...48,255,946
Ensembl chr19:48,180,770...48,255,946 		JBrowse link
G CASP6 caspase 6 involved_in IDA (PMID:32298652) UniProt PMID:32298652 NCBI chr 4:109,664,388...109,709,767
Ensembl chr 4:109,688,622...109,703,583 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IEA
IBA
IDA
IMP		 (PMID:23258413), (PMID:23929945), (PMID:24077100), (PMID:26046437), (PMID:28363908), (PMID:29426904), (PMID:30007416), (PMID:32817552), (PMID:32911482), (PMID:32912999), (PMID:33542149), (PMID:35438208) Ensembl
GO_Central
UniProt		 PMID:23258413 PMID:23929945 PMID:24077100 PMID:26046437 PMID:28363908 More... GO_REF:0000033 GO_REF:0000107 NCBI chr 6:73,423,711...73,452,297
Ensembl chr 6:73,413,515...73,452,297 		JBrowse link
G GBP1 guanylate binding protein 1 involved_in ISO (PMID:24739961) UniProt PMID:24739961 NCBI chr 1:89,052,319...89,065,208
Ensembl chr 1:89,051,882...89,065,360 		JBrowse link
G GBP2 guanylate binding protein 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:89,106,132...89,126,114
Ensembl chr 1:89,106,132...89,150,456 		JBrowse link
G GBP4 guanylate binding protein 4 involved_in ISO (PMID:24739961) UniProt PMID:24739961 NCBI chr 1:89,181,144...89,198,942
Ensembl chr 1:89,181,144...89,198,942 		JBrowse link
G GBP5 guanylate binding protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:89,256,189...89,272,860
Ensembl chr 1:89,256,189...89,272,860 		JBrowse link
G GBP7 guanylate binding protein 7 involved_in ISO (PMID:24739961) UniProt PMID:24739961 NCBI chr 1:89,131,742...89,176,003
Ensembl chr 1:89,131,742...89,176,009 		JBrowse link
G HEXIM1 HEXIM P-TEFb complex subunit 1 involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr17:45,148,475...45,152,099
Ensembl chr17:45,148,475...45,152,099 		JBrowse link
G HMGB1 high mobility group box 1 involved_in IDA (PMID:24971542) UniProt PMID:24971542 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 involved_in IDA (PMID:20628368) UniProt PMID:20628368 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G IFI16 interferon gamma inducible protein 16 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:158,999,976...159,055,151
Ensembl chr 1:158,999,968...159,055,155 		JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:206,470,476...206,496,889
Ensembl chr 1:206,470,476...206,496,889 		JBrowse link
G MATR3 matrin 3 involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr 5:139,274,101...139,331,677
Ensembl chr 5:139,273,752...139,331,671
Ensembl chr 5:139,273,752...139,331,671 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IDA (PMID:20628368) UniProt PMID:20628368 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123 		JBrowse link
G MNDA myeloid cell nuclear differentiation antigen involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:158,831,351...158,849,502
Ensembl chr 1:158,831,351...158,849,506 		JBrowse link
G NLRC4 NLR family CARD domain containing 4 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:32,224,449...32,265,743
Ensembl chr 2:32,224,453...32,265,732 		JBrowse link
G NLRP1 NLR family pyrin domain containing 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:5,501,396...5,584,509
Ensembl chr17:5,499,415...5,619,424 		JBrowse link
G NLRP10 NLR family pyrin domain containing 10 involved_in IMP (PMID:22672233) UniProt PMID:22672233 NCBI chr11:7,957,537...7,965,447
Ensembl chr11:7,957,537...7,965,447 		JBrowse link
G NONO non-POU domain containing octamer binding involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr  X:71,283,635...71,301,168
Ensembl chr  X:71,254,814...71,301,522 		JBrowse link
G PQBP1 polyglutamine binding protein 1 involved_in IDA (PMID:26046437) UniProt PMID:26046437 NCBI chr  X:48,897,930...48,903,143
Ensembl chr  X:48,890,197...48,903,402 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178 		JBrowse link
G PSPC1 paraspeckle component 1 involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr13:19,671,205...19,782,945
Ensembl chr13:19,674,752...19,783,019 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G PYHIN1 pyrin and HIN domain family member 1 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:158,931,552...158,990,870
Ensembl chr 1:158,930,796...158,977,059 		JBrowse link
G RBM14 RNA binding motif protein 14 involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr11:66,616,630...66,629,934
Ensembl chr11:66,616,626...66,629,934 		JBrowse link
G RBM14-RBM4 RBM14-RBM4 readthrough involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr11:66,616,630...66,646,468
Ensembl chr11:66,616,626...66,646,469 		JBrowse link
G SFPQ splicing factor proline and glutamine rich involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr 1:35,176,380...35,193,145
Ensembl chr 1:35,176,378...35,193,446 		JBrowse link
G SIN3A SIN3 transcription regulator family member A involved_in IMP (PMID:22783022) BHF-UCL PMID:22783022 NCBI chr15:75,369,379...75,455,815
Ensembl chr15:75,369,379...75,455,842 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IEA
IBA
IDA		 (PMID:23910378) Ensembl
GO_Central
ComplexPortal
InterPro		 PMID:23910378 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in
acts_upstream_of_or_within		 IDA
IEA
IBA		 (PMID:25636800) UniProt
Ensembl
GO_Central		 PMID:25636800 GO_REF:0000033 GO_REF:0000107 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR9 toll like receptor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TOMM70 translocase of outer mitochondrial membrane 70 involved_in IDA (PMID:20628368) UniProt PMID:20628368 NCBI chr 3:100,363,431...100,401,089
Ensembl chr 3:100,363,431...100,401,089 		JBrowse link
G TRIM5 tripartite motif containing 5 involved_in IDA (PMID:21512573) UniProt PMID:21512573 NCBI chr11:5,588,635...5,685,074
Ensembl chr11:5,663,195...5,938,619 		JBrowse link
G XRCC5 X-ray repair cross complementing 5 involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr 2:216,109,348...216,206,293
Ensembl chr 2:216,107,464...216,206,303 		JBrowse link
G XRCC6 X-ray repair cross complementing 6 involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr22:41,621,295...41,664,041
Ensembl chr22:41,621,163...41,664,048 		JBrowse link
G ZBP1 Z-DNA binding protein 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr20:57,603,852...57,620,426
Ensembl chr20:57,603,846...57,620,576 		JBrowse link
G ZCCHC3 zinc finger CCHC-type containing 3 involved_in IEA
IBA
IDA		 (PMID:30135424), (PMID:30193849) Ensembl
GO_Central
InterPro
UniProt		 PMID:30135424 PMID:30193849 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr20:297,570...300,321
Ensembl chr20:297,570...300,321 		JBrowse link
G ZNFX1 zinc finger NFX1-type containing 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:49,245,900...49,278,057
Ensembl chr20:49,237,946...49,278,426 		JBrowse link
CARD8 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARD8 caspase recruitment domain family member 8 involved_in IDA (PMID:31525884), (PMID:33053349), (PMID:33420028), (PMID:33420033) UniProt PMID:31525884 PMID:33053349 PMID:33420028 PMID:33420033 NCBI chr19:48,203,148...48,255,946
Ensembl chr19:48,180,770...48,255,946 		JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in IDA (PMID:15294986) AgBase PMID:15294986 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CLEC7A C-type lectin domain containing 7A acts_upstream_of_or_within
involved_in		 ISO
IDA		 (PMID:12719478)
(PMID:19358895)		 MGI
ARUK-UCL		 PMID:12719478 PMID:19358895 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
G COLEC10 collectin subfamily member 10 involved_in NAS (PMID:24174618) ComplexPortal PMID:24174618 NCBI chr 8:118,952,263...119,108,455
Ensembl chr 8:118,995,452...119,108,455 		JBrowse link
G COLEC11 collectin subfamily member 11 involved_in NAS (PMID:24174618) ComplexPortal PMID:24174618 NCBI chr 2:3,595,112...3,644,644
Ensembl chr 2:3,594,832...3,644,644 		JBrowse link
G FCN1 ficolin 1 involved_in IMP
NAS		 (PMID:21037097) UniProt
ComplexPortal		 PMID:21037097 NCBI chr 9:134,903,232...134,917,912
Ensembl chr 9:134,903,232...134,917,912 		JBrowse link
G FCN2 ficolin 2 involved_in NAS (PMID:17215869) ComplexPortal PMID:17215869 NCBI chr 9:134,864,144...134,887,523
Ensembl chr 9:134,880,810...134,887,523 		JBrowse link
G FCN3 ficolin 3 involved_in NAS (PMID:17215869) ComplexPortal PMID:17215869 NCBI chr 1:27,369,110...27,374,824
Ensembl chr 1:27,369,110...27,374,824 		JBrowse link
G FFAR2 free fatty acid receptor 2 involved_in IMP (PMID:21037097) UniProt PMID:21037097 NCBI chr19:35,448,257...35,451,767
Ensembl chr19:35,443,907...35,451,767 		JBrowse link
G LBP lipopolysaccharide binding protein involved_in IDA (PMID:15294986) AgBase PMID:15294986 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G MBL2 mannose binding lectin 2 involved_in IDA (PMID:22966085) ComplexPortal PMID:22966085 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IMP (PMID:19358895) ARUK-UCL PMID:19358895 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CGAS cyclic GMP-AMP synthase involved_in TAS
IEA
IDA		 (PMID:37403426)
(PMID:32911482), (PMID:32912999), (PMID:33542149), (PMID:35322803), (PMID:35438208), (PMID:35460603), (PMID:39322678)		 FlyBase
Ensembl
UniProt		 PMID:32911482 PMID:32912999 PMID:33542149 PMID:35322803 PMID:35438208 More... GO_REF:0000107 NCBI chr 6:73,423,711...73,452,297
Ensembl chr 6:73,413,515...73,452,297 		JBrowse link
G DDX41 DEAD-box helicase 41 involved_in IDA (PMID:35613581) UniProt PMID:35613581 NCBI chr 5:177,511,577...177,516,961
Ensembl chr 5:177,511,577...177,516,961 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in TAS (PMID:37403426) FlyBase PMID:37403426 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IEA
TAS
IDA		 (PMID:37403426)
(PMID:25636800), (PMID:30842659), (PMID:30842662), (PMID:35388221), (PMID:37832545)		 Ensembl
FlyBase
UniProt		 PMID:25636800 PMID:30842659 PMID:30842662 PMID:35388221 PMID:37403426 More... GO_REF:0000107 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in TAS (PMID:37403426) FlyBase PMID:37403426 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALPK1 alpha kinase 1 involved_in TAS
IBA
IDA		 (PMID:28222186), (PMID:28877472), (PMID:30111836) Reactome
GO_Central
UniProt		 PMID:28222186 PMID:28877472 PMID:30111836 GO_REF:0000033 Reactome:R-HSA-9645460 NCBI chr 4:112,297,369...112,442,621
Ensembl chr 4:112,285,509...112,442,621 		JBrowse link
G BECN1 beclin 1 involved_in IDA (PMID:34796041) UniProt PMID:34796041 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IDA (PMID:23258413) UniProt PMID:23258413 NCBI chr 6:73,423,711...73,452,297
Ensembl chr 6:73,413,515...73,452,297 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in IDA (PMID:23478265) UniProt PMID:23478265 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IMP
IBA		 (PMID:19211564) UniProt
GO_Central		 PMID:19211564 GO_REF:0000033 NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714 		JBrowse link
G IFIH1 interferon induced with helicase C domain 1 involved_in TAS (PMID:21616437) UniProt PMID:21616437 NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684 		JBrowse link
G IPO5 importin 5 involved_in IDA (PMID:31340999) UniProt PMID:31340999 NCBI chr13:97,953,675...98,024,296
Ensembl chr13:97,953,658...98,024,296 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IDA (PMID:8524823) UniProt PMID:8524823 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G IRF7 interferon regulatory factor 7 involved_in IDA (PMID:21931555) UniProt PMID:21931555 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in TAS Reactome Reactome:R-HSA-9645460 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IDA (PMID:16125763), (PMID:20451243) UniProt PMID:16125763 PMID:20451243 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123 		JBrowse link
G RIGI RNA sensor RIG-I involved_in TAS
IBA
IDA		 (PMID:21616437)
(PMID:19576794)		 UniProt
GO_Central		 PMID:19576794 PMID:21616437 GO_REF:0000033 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,348 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IDA (PMID:23910378), (PMID:35388221) UniProt PMID:23910378 PMID:35388221 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IDA (PMID:29441066) UniProt PMID:29441066 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TIFA TRAF interacting protein with forkhead associated domain involved_in IDA
IBA		 (PMID:26068852), (PMID:28222186), (PMID:28877472), (PMID:30111836) UniProt
GO_Central		 PMID:26068852 PMID:28222186 PMID:28877472 PMID:30111836 GO_REF:0000033 NCBI chr 4:112,274,537...112,285,904
Ensembl chr 4:112,272,968...112,285,955 		JBrowse link
G TRAF3IP3 TRAF3 interacting protein 3 involved_in IDA
IBA		 (PMID:31390091) UniProt
GO_Central		 PMID:31390091 GO_REF:0000033 NCBI chr 1:209,756,053...209,782,310
Ensembl chr 1:209,756,032...209,782,320 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in TAS
IDA		 (PMID:20501938), (PMID:23015697) Reactome
UniProt		 PMID:20501938 PMID:23015697 Reactome:R-HSA-9645460 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TRIM25 tripartite motif containing 25 involved_in IDA (PMID:17392790) UniProt PMID:17392790 NCBI chr17:56,887,909...56,914,049
Ensembl chr17:56,836,387...56,914,080 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in IDA (PMID:22607805) UniProt PMID:22607805 NCBI chr17:1,344,275...1,400,222
Ensembl chr17:1,344,275...1,400,222 		JBrowse link
endolysosomal toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WASHC4 WASH complex subunit 4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:105,107,731...105,169,130
Ensembl chr12:105,107,324...105,169,130 		JBrowse link
inflammasome-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ELP6 elongator acetyltransferase complex subunit 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:47,495,640...47,513,712
Ensembl chr 3:47,495,640...47,513,712 		JBrowse link
innate immune response activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LILRA2 leukocyte immunoglobulin like receptor A2 involved_in IDA (PMID:27572839) UniProt PMID:27572839 NCBI chr19:54,572,988...54,590,287
Ensembl chr19:54,572,920...54,590,287 		JBrowse link
innate immune response-activating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HCK HCK proto-oncogene, Src family tyrosine kinase involved_in TAS (PMID:18538446) UniProt PMID:18538446 NCBI chr20:32,052,242...32,101,856
Ensembl chr20:32,052,197...32,101,856 		JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:19226379 RGD:2312509 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFIH1 interferon induced with helicase C domain 1 involved_in IDA
IBA
IMP		 (PMID:17600090), (PMID:33727702)
(PMID:19211564)		 UniProt
GO_Central		 PMID:17600090 PMID:19211564 PMID:33727702 GO_REF:0000033 NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in TAS (PMID:16979567) UniProt PMID:16979567 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G IRF7 interferon regulatory factor 7 involved_in TAS (PMID:16979567) UniProt PMID:16979567 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983 		JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 involved_in IMP (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chr12:112,938,474...112,973,251
Ensembl chr12:112,938,051...112,976,460 		JBrowse link
MyD88-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRFIP2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chr 3:37,052,626...37,176,360
Ensembl chr 3:37,052,626...37,183,689 		JBrowse link
MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-166058 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 involved_in IDA (PMID:16148103) BHF-UCL PMID:16148103 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-166058 Reactome:R-HSA-975871 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in TAS (PMID:10383454) BHF-UCL PMID:10383454 Reactome:R-HSA-166058 Reactome:R-HSA-975871 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 involved_in TAS (PMID:10383454) BHF-UCL PMID:10383454 NCBI chr 3:10,164,919...10,243,745
Ensembl chr 3:10,164,919...10,243,745 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 involved_in TAS (PMID:10383454) BHF-UCL PMID:10383454 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 involved_in TAS (PMID:21269878) UniProt PMID:21269878 Reactome:R-HSA-166058 Reactome:R-HSA-975871 NCBI chr12:43,758,951...43,789,541
Ensembl chr12:43,758,944...43,798,307 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in TAS Reactome Reactome:R-HSA-166058 Reactome:R-HSA-975871 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in
acts_upstream_of_or_within		 IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G REG3G regenerating family member 3 gamma involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:79,025,702...79,028,501
Ensembl chr 2:79,025,686...79,028,505 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in TAS (PMID:19509286) BHF-UCL PMID:19509286 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR4 toll like receptor 4 involved_in ISS
IDA
IBA
IEA		 (PMID:20037584), (PMID:38670073) ARUK-UCL
ComplexPortal
GO_Central
Ensembl		 PMID:20037584 PMID:38670073 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR6 toll like receptor 6 involved_in IDA
IEA
ISS		 (PMID:20037584) ComplexPortal
Ensembl
ARUK-UCL		 PMID:20037584 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G TLR9 toll like receptor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:151,029,943...151,087,685
Ensembl chr 5:151,029,945...151,093,577 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in TAS Reactome Reactome:R-HSA-166058 Reactome:R-HSA-975871 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRFIP2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chr 3:37,052,626...37,176,360
Ensembl chr 3:37,052,626...37,183,689 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712 		JBrowse link
G TNIP3 TNFAIP3 interacting protein 3 involved_in IDA (PMID:17088249) UniProt PMID:17088249 NCBI chr 4:121,131,408...121,227,483
Ensembl chr 4:121,131,408...121,227,466 		JBrowse link
negative regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFI16 interferon gamma inducible protein 16 involved_in IDA (PMID:30104205) UniProt PMID:30104205 NCBI chr 1:158,999,976...159,055,151
Ensembl chr 1:158,999,968...159,055,155 		JBrowse link
G PYDC5 pyrin domain containing 5 involved_in IDA (PMID:24531343) UniProt PMID:24531343 NCBI chr 1:158,999,971...159,002,751
Ensembl chr 1:158,999,971...159,002,751 		JBrowse link
G TRIM11 tripartite motif containing 11 involved_in IDA (PMID:27498865) UniProt PMID:27498865 NCBI chr 1:228,393,676...228,406,835
Ensembl chr 1:228,393,673...228,406,835 		JBrowse link
negative regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPINK5 serine peptidase inhibitor Kazal type 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:148,063,980...148,137,382
Ensembl chr 5:148,025,683...148,137,382 		JBrowse link
negative regulation of antifungal innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAM3A FAM3 metabolism regulating signaling molecule A involved_in IDA (PMID:18212107) UniProt PMID:18212107 NCBI chr  X:154,506,171...154,516,232
Ensembl chr  X:154,506,159...154,516,242 		JBrowse link
G USP15 ubiquitin specific peptidase 15 involved_in IDA (PMID:33093067) UniProt PMID:33093067 NCBI chr12:62,260,404...62,416,389
Ensembl chr12:62,260,338...62,417,431 		JBrowse link
negative regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AARS2 alanyl-tRNA synthetase 2, mitochondrial involved_in IDA
IEA		 (PMID:39322678) UniProt
Ensembl		 PMID:39322678 GO_REF:0000107 NCBI chr 6:44,298,731...44,313,347
Ensembl chr 6:44,298,731...44,313,347 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 involved_in IDA (PMID:12172553), (PMID:26440888) UniProt PMID:12172553 PMID:26440888 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G AURKB aurora kinase B involved_in IDA (PMID:33542149) UniProt PMID:33542149 NCBI chr17:8,204,731...8,210,575
Ensembl chr17:8,204,733...8,210,600 		JBrowse link
G BANF1 barrier to autointegration nuclear assembly factor 1 involved_in IDA (PMID:32792394) UniProt PMID:32792394 NCBI chr11:66,002,079...66,004,149
Ensembl chr11:66,002,228...66,004,149 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IDA (PMID:32911482), (PMID:32912999) UniProt PMID:32911482 PMID:32912999 NCBI chr 6:73,423,711...73,452,297
Ensembl chr 6:73,413,515...73,452,297 		JBrowse link
G IRGM immunity related GTPase M involved_in IDA (PMID:32715615) UniProt PMID:32715615 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736 		JBrowse link
G LYPLAL1 lysophospholipase like 1 involved_in IDA (PMID:37802025) UniProt PMID:37802025 NCBI chr 1:219,173,878...219,445,496
Ensembl chr 1:219,173,869...219,212,865 		JBrowse link
G MIR4691 microRNA 4691 involved_in IMP (PMID:37403426) FlyBase PMID:37403426 NCBI chr11:68,033,897...68,033,981
Ensembl chr11:68,033,897...68,033,981 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IDA (PMID:35460603) UniProt PMID:35460603 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PCBP2 poly(rC) binding protein 2 involved_in IDA (PMID:35322803) UniProt PMID:35322803 NCBI chr12:53,452,102...53,481,162
Ensembl chr12:53,452,102...53,481,162 		JBrowse link
G PPP6C protein phosphatase 6 catalytic subunit involved_in IDA (PMID:32474700) UniProt PMID:32474700 NCBI chr 9:125,146,573...125,189,803
Ensembl chr 9:125,146,573...125,189,939 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IDA (PMID:33273464) UniProt PMID:33273464 NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178 		JBrowse link
G SMPDL3A sphingomyelin phosphodiesterase acid like 3A involved_in IMP
IEA		 (PMID:37890481) UniProt
Ensembl		 PMID:37890481 GO_REF:0000107 NCBI chr 6:122,789,258...122,809,720
Ensembl chr 6:122,789,049...122,809,720 		JBrowse link
G SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 involved_in IDA (PMID:38418882) UniProt PMID:38418882 NCBI chr16:1,776,712...1,782,571
Ensembl chr16:1,776,712...1,793,700 		JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in IDA (PMID:33476576) UniProt PMID:33476576 NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645 		JBrowse link
G ZDHHC18 zinc finger DHHC-type palmitoyltransferase 18 involved_in IDA (PMID:35438208) UniProt PMID:35438208 NCBI chr 1:26,826,688...26,857,604
Ensembl chr 1:26,826,688...26,857,604 		JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chr 1:207,752,038...207,795,516
Ensembl chr 1:207,752,037...207,795,513 		JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in IDA (PMID:10531307) UniProt PMID:10531307 NCBI chr 1:207,496,157...207,641,765
Ensembl chr 1:207,496,147...207,641,765 		JBrowse link
G SUSD4 sushi domain containing 4 involved_in IDA (PMID:23482636) UniProt PMID:23482636 NCBI chr 1:223,220,831...223,365,235
Ensembl chr 1:223,220,819...223,364,233 		JBrowse link
G VSIG4 V-set and immunoglobulin domain containing 4 involved_in IPI
IBA		 (PMID:17051150) UniProt
GO_Central		 PMID:17051150 GO_REF:0000033 NCBI chr  X:66,021,738...66,040,080
Ensembl chr  X:66,021,738...66,040,125 		JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin involved_in IDA (PMID:12538697) UniProt PMID:12538697 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229 		JBrowse link
G SERPING1 serpin family G member 1 involved_in IDA (PMID:10946292) UniProt PMID:10946292 NCBI chr11:57,597,685...57,614,848
Ensembl chr11:57,597,387...57,619,171 		JBrowse link
negative regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITCH itchy E3 ubiquitin protein ligase involved_in IDA (PMID:27736772) UniProt PMID:27736772 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,235...34,511,773 		JBrowse link
G MARCHF5 membrane associated ring-CH-type finger 5 involved_in IDA (PMID:31881323) UniProt PMID:31881323 NCBI chr10:92,291,167...92,353,964
Ensembl chr10:92,291,167...92,353,964 		JBrowse link
G RNF39 ring finger protein 39 involved_in IDA (PMID:33674311) UniProt PMID:33674311 NCBI chr 6:30,070,270...30,075,769
Ensembl chr 6:30,070,266...30,075,849 		JBrowse link
G SEC14L1 SEC14 like lipid binding 1 involved_in IDA (PMID:23843640) UniProt PMID:23843640 NCBI chr17:77,088,685...77,217,101
Ensembl chr17:77,088,749...77,217,101 		JBrowse link
G TARBP2 TARBP2 subunit of RISC loading complex involved_in IDA (PMID:30927622) UniProt PMID:30927622 NCBI chr12:53,500,923...53,506,431
Ensembl chr12:53,500,921...53,506,431 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 involved_in IDA (PMID:27736772) UniProt PMID:27736772 NCBI chr 7:27,739,373...27,829,767
Ensembl chr 7:27,739,331...27,844,564 		JBrowse link
G TSPAN6 tetraspanin 6 involved_in IMP (PMID:22908223) UniProt PMID:22908223 NCBI chr  X:100,627,108...100,637,104
Ensembl chr  X:100,627,108...100,639,991 		JBrowse link
negative regulation of defense response to bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG2 arginase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G MAPKBP1 mitogen-activated protein kinase binding protein 1 involved_in IMP (PMID:22700971) UniProt PMID:22700971 NCBI chr15:41,774,484...41,827,855
Ensembl chr15:41,774,434...41,827,855 		JBrowse link
G MIR181B1 microRNA 181b-1 involved_in IGI (PMID:25505240) ARUK-UCL PMID:25505240 NCBI chr 1:198,858,873...198,858,982
Ensembl chr 1:198,858,873...198,858,982 		JBrowse link
G MIR181B2 microRNA 181b-2 involved_in IGI (PMID:25505240) ARUK-UCL PMID:25505240 NCBI chr 9:124,693,710...124,693,798
Ensembl chr 9:124,693,710...124,693,798 		JBrowse link
G PTEN phosphatase and tensin homolog ISO RGD PMID:18056380 RGD:2292524 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
negative regulation of defense response to virus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG12 autophagy related 12 involved_in IDA
IEA		 (PMID:19666601) ComplexPortal
Ensembl		 PMID:19666601 GO_REF:0000107 NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837 		JBrowse link
G ATG5 autophagy related 5 involved_in IEA
IDA		 (PMID:19666601) Ensembl
ComplexPortal		 PMID:19666601 GO_REF:0000107 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791 		JBrowse link
G C1QBP complement C1q binding protein involved_in IMP (PMID:19164550) UniProt PMID:19164550 NCBI chr17:5,432,777...5,439,155
Ensembl chr17:5,432,777...5,448,830 		JBrowse link
G FGL2 fibrinogen like 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:77,193,369...77,199,819
Ensembl chr 7:77,193,369...77,199,848 		JBrowse link
G FOXP3 forkhead box P3 involved_in ISO
IEA		 RGD
Ensembl		 PMID:17878294 GO_REF:0000107 RGD:2325989 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G HTRA1 HtrA serine peptidase 1 ISO RGD PMID:15333144 RGD:2311622 NCBI chr10:122,461,553...122,514,907
Ensembl chr10:122,458,551...122,514,907 		JBrowse link
G ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains involved_in IMP (PMID:29802199) UniProt PMID:29802199 NCBI chr 6:34,587,288...34,696,767
Ensembl chr 6:34,587,288...34,696,859 		JBrowse link
G IRGM immunity related GTPase M involved_in IDA (PMID:34467632), (PMID:36221902) UniProt PMID:34467632 PMID:36221902 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736 		JBrowse link
G ITCH itchy E3 ubiquitin protein ligase involved_in IMP
IEA		 (PMID:19881509) UniProt
Ensembl		 PMID:19881509 GO_REF:0000107 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,235...34,511,773 		JBrowse link
G MIR26B microRNA 26b involved_in IDA (PMID:26222045) ARUK-UCL PMID:26222045 NCBI chr 2:218,402,646...218,402,722
Ensembl chr 2:218,402,646...218,402,722 		JBrowse link
G PCBP2 poly(rC) binding protein 2 involved_in IMP (PMID:19881509) UniProt PMID:19881509 NCBI chr12:53,452,102...53,481,162
Ensembl chr12:53,452,102...53,481,162 		JBrowse link
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B involved_in IMP (PMID:22750291) UniProt PMID:22750291 NCBI chr 2:44,168,875...44,246,928
Ensembl chr 2:44,167,969...44,244,384 		JBrowse link
G RNF26 ring finger protein 26 involved_in IDA (PMID:25254379) UniProt PMID:25254379 NCBI chr11:119,334,527...119,337,309
Ensembl chr11:119,334,527...119,337,309 		JBrowse link
G TRAF3IP1 TRAF3 interacting protein 1 involved_in
acts_upstream_of_or_within		 IMP
IEA
ISO		 (PMID:22079989) CACAO
Ensembl
MGI		 PMID:22079989 GO_REF:0000107 NCBI chr 2:238,320,518...238,400,900
Ensembl chr 2:238,320,441...238,400,897 		JBrowse link
G TRIM38 tripartite motif containing 38 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:25,962,802...25,991,231
Ensembl chr 6:25,962,802...25,991,231 		JBrowse link
negative regulation of defense response to virus by host term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 involved_in IMP (PMID:23399697) UniProt PMID:23399697 NCBI chr 1:20,499,448...20,508,151
Ensembl chr 1:20,499,448...20,508,151 		JBrowse link
G NT5C2 5'-nucleotidase, cytosolic II involved_in IDA (PMID:36159777) UniProt PMID:36159777 NCBI chr10:103,088,017...103,193,272
Ensembl chr10:103,087,185...103,277,605 		JBrowse link
G TARBP2 TARBP2 subunit of RISC loading complex involved_in IDA (PMID:11641396) UniProt PMID:11641396 NCBI chr12:53,500,923...53,506,431
Ensembl chr12:53,500,921...53,506,431 		JBrowse link
negative regulation of immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
negative regulation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638 		JBrowse link
G ATG12 autophagy related 12 involved_in IEA
ISO		 Ensembl
ComplexPortal		 GO_REF:0000107 GO_REF:0000114 NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837 		JBrowse link
G ATG5 autophagy related 5 involved_in IEA
ISO		 Ensembl
ComplexPortal		 GO_REF:0000107 GO_REF:0000114 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791 		JBrowse link
G AURKB aurora kinase B involved_in IDA (PMID:33542149) UniProt PMID:33542149 NCBI chr17:8,204,731...8,210,575
Ensembl chr17:8,204,733...8,210,600 		JBrowse link
G BANF1 barrier to autointegration nuclear assembly factor 1 involved_in IDA (PMID:32792394) UniProt PMID:32792394 NCBI chr11:66,002,079...66,004,149
Ensembl chr11:66,002,228...66,004,149 		JBrowse link
G CACTIN cactin, spliceosome C complex subunit involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:3,610,645...3,626,790
Ensembl chr19:3,610,645...3,626,815 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 involved_in ISO (PMID:15557190) BHF-UCL PMID:15557190 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313 		JBrowse link
G CEP63 centrosomal protein 63 involved_in IDA (PMID:35793002) UniProt PMID:35793002 NCBI chr 3:134,485,724...134,782,559
Ensembl chr 3:134,485,699...134,587,789 		JBrowse link
G DDX39A DExD-box helicase 39A involved_in IDA (PMID:32393512) UniProt PMID:32393512 NCBI chr19:14,408,798...14,419,383
Ensembl chr19:14,408,798...14,419,383 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA
IDA		 (PMID:21525357) Ensembl
UniProt		 PMID:21525357 GO_REF:0000107 NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714 		JBrowse link
G DRD2 dopamine receptor D2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G DTX4 deltex E3 ubiquitin ligase 4 involved_in IDA (PMID:27692986), (PMID:35793002) UniProt PMID:27692986 PMID:35793002 NCBI chr11:59,171,430...59,208,588
Ensembl chr11:59,171,430...59,208,588 		JBrowse link
G GRN granulin precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G IFI16 interferon gamma inducible protein 16 involved_in IDA (PMID:22046441), (PMID:30104205) UniProt PMID:22046441 PMID:30104205 NCBI chr 1:158,999,976...159,055,151
Ensembl chr 1:158,999,968...159,055,155 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 involved_in ISS
IEA		 (PMID:12150927) BHF-UCL
Ensembl		 PMID:12150927 GO_REF:0000107 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622 		JBrowse link
G LYAR Ly1 antibody reactive involved_in IDA (PMID:31413131) ARUK-UCL PMID:31413131 NCBI chr 4:4,267,701...4,290,154
Ensembl chr 4:4,267,701...4,290,154 		JBrowse link
G MIR181B1 microRNA 181b-1 involved_in IGI (PMID:25505240) ARUK-UCL PMID:25505240 NCBI chr 1:198,858,873...198,858,982
Ensembl chr 1:198,858,873...198,858,982 		JBrowse link
G MIR181B2 microRNA 181b-2 involved_in IGI (PMID:25505240) ARUK-UCL PMID:25505240 NCBI chr 9:124,693,710...124,693,798
Ensembl chr 9:124,693,710...124,693,798 		JBrowse link
G MIR21 microRNA 21 involved_in IMP (PMID:22286305) BHF-UCL PMID:22286305 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR4691 microRNA 4691 involved_in IMP (PMID:37403426) FlyBase PMID:37403426 NCBI chr11:68,033,897...68,033,981
Ensembl chr11:68,033,897...68,033,981 		JBrowse link
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 involved_in IMP (PMID:23399697) UniProt PMID:23399697 NCBI chr 1:20,499,448...20,508,151
Ensembl chr 1:20,499,448...20,508,151 		JBrowse link
G NLRC3 NLR family CARD domain containing 3 involved_in ISS UniProt GO_REF:0000024 NCBI chr16:3,539,033...3,577,403
Ensembl chr16:3,539,033...3,577,403 		JBrowse link
G NLRP4 NLR family pyrin domain containing 4 involved_in IDA (PMID:27692986) UniProt PMID:27692986 NCBI chr19:55,836,540...55,881,855
Ensembl chr19:55,836,540...55,881,855 		JBrowse link
G NLRX1 NLR family member X1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:119,168,334...119,184,016
Ensembl chr11:119,166,568...119,184,016 		JBrowse link
G NMI N-myc and STAT interactor involved_in
acts_upstream_of_or_within		 IMP
IEA		 (PMID:26342464) UniProt
Ensembl		 PMID:26342464 GO_REF:0000107 NCBI chr 2:151,270,470...151,289,668
Ensembl chr 2:151,270,470...151,289,894 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IDA
IMP		 (PMID:35460603)
(PMID:32844745)		 UniProt PMID:32844745 PMID:35460603 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PIM1 Pim-1 proto-oncogene, serine/threonine kinase involved_in IDA (PMID:37797010) UniProt PMID:37797010 NCBI chr 6:37,170,152...37,175,428
Ensembl chr 6:37,170,152...37,175,428 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 involved_in IDA (PMID:34811497) UniProt PMID:34811497 NCBI chr12:6,946,577...6,961,316
Ensembl chr12:6,946,468...6,961,316 		JBrowse link
G SFN stratifin involved_in IDA (PMID:37797010) UniProt PMID:37797010 NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TRAFD1 TRAF-type zinc finger domain containing 1 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:112,125,560...112,153,604
Ensembl chr12:112,125,538...112,153,604 		JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in IDA (PMID:33476576) UniProt PMID:33476576 NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645 		JBrowse link
G TRIM21 tripartite motif containing 21 involved_in IDA (PMID:26342464) UniProt PMID:26342464 NCBI chr11:4,384,897...4,393,702
Ensembl chr11:4,384,897...4,393,702 		JBrowse link
G TYRO3 TYRO3 protein tyrosine kinase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:41,559,212...41,583,589
Ensembl chr15:41,557,675...41,583,589 		JBrowse link
G USP38 ubiquitin specific peptidase 38 involved_in IDA (PMID:27692986) UniProt PMID:27692986 NCBI chr 4:143,184,917...143,223,874
Ensembl chr 4:143,184,917...143,225,212 		JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta involved_in IDA (PMID:35662396) UniProt PMID:35662396 NCBI chr 8:100,916,523...100,953,382
Ensembl chr 8:100,916,523...100,953,388 		JBrowse link
G ZDHHC18 zinc finger DHHC-type palmitoyltransferase 18 involved_in IDA (PMID:35438208) UniProt PMID:35438208 NCBI chr 1:26,826,688...26,857,604
Ensembl chr 1:26,826,688...26,857,604 		JBrowse link
negative regulation of lipopolysaccharide-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACTIN cactin, spliceosome C complex subunit involved_in IMP (PMID:20829348) UniProt PMID:20829348 NCBI chr19:3,610,645...3,626,790
Ensembl chr19:3,610,645...3,626,815 		JBrowse link
G CARD16 caspase recruitment domain family member 16 involved_in IDA (PMID:11432859) UniProt PMID:11432859 NCBI chr11:105,041,563...105,045,335
Ensembl chr11:105,039,092...105,101,431 		JBrowse link
G CARD8 caspase recruitment domain family member 8 involved_in IDA (PMID:11821383) UniProt PMID:11821383 NCBI chr19:48,203,148...48,255,946
Ensembl chr19:48,180,770...48,255,946 		JBrowse link
G DEFB114 defensin beta 114 involved_in IDA (PMID:23482568) UniProt PMID:23482568 NCBI chr 6:49,960,249...49,964,164
Ensembl chr 6:49,960,249...49,964,164 		JBrowse link
G DEFB118 defensin beta 118 involved_in IDA (PMID:33181266) UniProt PMID:33181266 NCBI chr20:31,368,601...31,373,923
Ensembl chr20:31,368,601...31,373,923 		JBrowse link
G LACRT lacritin involved_in IDA (PMID:26670139) FlyBase PMID:26670139 NCBI chr12:54,630,811...54,634,895
Ensembl chr12:54,630,811...54,634,895 		JBrowse link
G LILRA2 leukocyte immunoglobulin like receptor A2 involved_in IMP (PMID:22479404) UniProt PMID:22479404 NCBI chr19:54,572,988...54,590,287
Ensembl chr19:54,572,920...54,590,287 		JBrowse link
G LTF lactotransferrin involved_in IDA (PMID:20345905) UniProt PMID:20345905 NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234 		JBrowse link
G NFKBIL1 NFKB inhibitor like 1 involved_in IDA (PMID:20829348) UniProt PMID:20829348 NCBI chr 6:31,546,851...31,558,829
Ensembl chr 6:31,546,870...31,558,829 		JBrowse link
G PRDX2 peroxiredoxin 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:6,946,577...6,961,316
Ensembl chr12:6,946,468...6,961,316 		JBrowse link
G SIGIRR single Ig and TIR domain containing involved_in TAS (PMID:15866876) HGNC-UCL PMID:15866876 NCBI chr11:405,716...417,397
Ensembl chr11:405,715...417,455 		JBrowse link
G SIRPA signal regulatory protein alpha involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr20:1,894,167...1,940,592
Ensembl chr20:1,894,167...1,940,592 		JBrowse link
G TRIB1 tribbles pseudokinase 1 involved_in IMP (PMID:17452330) BHF-UCL PMID:17452330 NCBI chr 8:125,430,358...125,438,403
Ensembl chr 8:125,430,358...125,438,403 		JBrowse link
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QBP complement C1q binding protein involved_in IDA (PMID:19164550) UniProt PMID:19164550 NCBI chr17:5,432,777...5,439,155
Ensembl chr17:5,432,777...5,448,830 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IMP (PMID:21187438) UniProt PMID:21187438 NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714 		JBrowse link
G RIOK3 RIO kinase 3 involved_in IMP (PMID:25865883) UniProt PMID:25865883 NCBI chr18:23,453,287...23,483,140
Ensembl chr18:23,453,287...23,486,603 		JBrowse link
G TKFC triokinase and FMN cyclase involved_in IDA (PMID:17600090) UniProt PMID:17600090 NCBI chr11:61,333,228...61,353,426
Ensembl chr11:61,333,220...61,353,295 		JBrowse link
negative regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300A CD300a molecule involved_in IMP (PMID:22043923) UniProt PMID:22043923 NCBI chr17:74,466,373...74,484,798
Ensembl chr17:74,466,399...74,484,798 		JBrowse link
G CD300LF CD300 molecule like family member f involved_in IMP (PMID:22043923) UniProt PMID:22043923 NCBI chr17:74,694,317...74,712,923
Ensembl chr17:74,694,311...74,712,978 		JBrowse link
negative regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SARM1 sterile alpha and TIR motif containing 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr17:28,371,694...28,404,049
Ensembl chr17:28,364,356...28,404,049 		JBrowse link
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD96 CD96 molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:111,542,197...111,665,996
Ensembl chr 3:111,292,719...111,665,996 		JBrowse link
G HLA-F major histocompatibility complex, class I, F involved_in IDA (PMID:24018270) UniProt PMID:24018270 NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528 		JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-F major histocompatibility complex, class I, F involved_in IDA (PMID:24018270) UniProt PMID:24018270 NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528 		JBrowse link
G LGALS9 galectin 9 involved_in ISO (PMID:23408620) UniProt PMID:23408620 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB2 arrestin beta 2 involved_in IMP (PMID:18604210) UniProt PMID:18604210 NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499 		JBrowse link
G CLEC12B C-type lectin domain family 12 member B involved_in IMP (PMID:17562706) UniProt PMID:17562706 NCBI chr12:10,006,209...10,018,800
Ensembl chr12:10,010,627...10,018,796 		JBrowse link
G CRK CRK proto-oncogene, adaptor protein involved_in ISO
IEA		 RGD
Ensembl		 PMID:18835194 GO_REF:0000107 RGD:11568650 NCBI chr17:1,420,693...1,456,232
Ensembl chr17:1,420,689...1,463,162 		JBrowse link
G GFER growth factor, augmenter of liver regeneration ISO RGD PMID:9021955 RGD:9685777 NCBI chr16:1,984,193...1,987,749
Ensembl chr16:1,984,193...1,987,749 		JBrowse link
G GRB2 growth factor receptor bound protein 2 involved_in IDA (PMID:25870599) UniProt PMID:25870599 NCBI chr17:75,318,076...75,405,678
Ensembl chr17:75,318,076...75,405,709 		JBrowse link
G HLA-E major histocompatibility complex, class I, E involved_in IDA (PMID:10799855), (PMID:17179229), (PMID:23335510), (PMID:9486650) UniProt PMID:9486650 PMID:10799855 PMID:17179229 PMID:23335510 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194 		JBrowse link
G HLA-F major histocompatibility complex, class I, F involved_in IDA (PMID:24018270) UniProt PMID:24018270 NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528 		JBrowse link
G HLA-G major histocompatibility complex, class I, G involved_in IDA
IMP		 (PMID:10190900)
(PMID:12874224)		 UniProt PMID:10190900 PMID:12874224 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125 		JBrowse link
G IGF2 insulin like growth factor 2 ISO RGD PMID:9021955 RGD:9685777 NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391 		JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D involved_in IDA (PMID:23154388) UniProt PMID:23154388 NCBI chr 2:233,060,342...233,207,903
Ensembl chr 2:233,059,967...233,207,903 		JBrowse link
G KIR2DL4 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 involved_in IDA (PMID:10190900) UniProt PMID:10190900 NCBI chr19:54,803,610...54,814,517
Ensembl chr19:54,803,610...54,814,517 		JBrowse link
G KLRC1 killer cell lectin like receptor C1 involved_in IDA
IBA		 (PMID:9485206), (PMID:9486650) UniProt
GO_Central		 PMID:9485206 PMID:9486650 GO_REF:0000033 NCBI chr12:10,442,264...10,454,685
Ensembl chr12:10,442,264...10,454,685 		JBrowse link
G KLRD1 killer cell lectin like receptor D1 involved_in IDA (PMID:9486650) UniProt PMID:9486650 NCBI chr12:10,238,961...10,329,608
Ensembl chr12:10,226,058...10,329,608 		JBrowse link
G LGALS9 galectin 9 involved_in IDA (PMID:23408620) UniProt PMID:23408620 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G LILRB1 leukocyte immunoglobulin like receptor B1 involved_in IDA (PMID:12874224), (PMID:18398485) UniProt PMID:12874224 PMID:18398485 NCBI chr19:54,616,322...54,638,022
Ensembl chr19:54,617,158...54,638,022 		JBrowse link
G MICA MHC class I polypeptide-related sequence A involved_in IMP (PMID:20068167) CACAO PMID:20068167 NCBI chr 6:31,400,711...31,415,315
Ensembl chr 6:31,399,784...31,415,315 		JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IDA (PMID:28515320) UniProt PMID:28515320 NCBI chr19:44,846,297...44,889,223
Ensembl chr19:44,846,175...44,889,223 		JBrowse link
G NECTIN4 nectin cell adhesion molecule 4 involved_in IDA (PMID:32503945) UniProt PMID:32503945 NCBI chr 1:161,070,998...161,089,558
Ensembl chr 1:161,070,998...161,089,558 		JBrowse link
G PVR PVR cell adhesion molecule involved_in IDA (PMID:23154388) UniProt PMID:23154388 NCBI chr19:44,643,910...44,666,162
Ensembl chr19:44,643,798...44,666,162 		JBrowse link
G SH2D1B SH2 domain containing 1B acts_upstream_of_or_within ISO (PMID:16127454) MGI PMID:16127454 NCBI chr 1:162,395,268...162,412,136
Ensembl chr 1:162,395,268...162,412,138 		JBrowse link
G TIGIT T cell immunoreceptor with Ig and ITIM domains involved_in IDA (PMID:23154388) UniProt PMID:23154388 NCBI chr 3:114,294,028...114,310,288
Ensembl chr 3:114,276,913...114,310,288 		JBrowse link
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEACAM1 CEA cell adhesion molecule 1 involved_in IMP (PMID:23696226) UniProt PMID:23696226 NCBI chr19:42,507,306...42,528,481
Ensembl chr19:42,507,304...42,561,234 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G KLRC4-KLRK1 KLRC4-KLRK1 readthrough ISO RGD PMID:12782717 RGD:1299590 NCBI chr12:10,372,353...10,410,146
Ensembl chr12:10,372,353...10,410,146
Ensembl chr12:10,372,353...10,410,146 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IDA (PMID:24586048) ARUK-UCL PMID:24586048 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD17A abhydrolase domain containing 17A, depalmitoylase involved_in IDA (PMID:38092000) UniProt PMID:38092000 NCBI chr19:1,876,810...1,885,496
Ensembl chr19:1,876,810...1,885,496 		JBrowse link
G ABHD8 abhydrolase domain containing 8 involved_in IEA
IMP		 (PMID:39225180) Ensembl
UniProt		 PMID:39225180 GO_REF:0000107 NCBI chr19:17,292,131...17,303,425
Ensembl chr19:17,292,131...17,310,236 		JBrowse link
G CARD8 caspase recruitment domain family member 8 involved_in IDA (PMID:24517500) UniProt PMID:24517500 NCBI chr19:48,203,148...48,255,946
Ensembl chr19:48,180,770...48,255,946 		JBrowse link
G CPTP ceramide-1-phosphate transfer protein involved_in IMP (PMID:29164996) UniProt PMID:29164996 NCBI chr 1:1,324,802...1,328,896
Ensembl chr 1:1,324,756...1,328,896 		JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 involved_in ISS (PMID:34615873) UniProt PMID:34615873 GO_REF:0000024 NCBI chr 5:149,492,982...149,551,439
Ensembl chr 5:149,492,982...149,551,471 		JBrowse link
G FBXL2 F-box and leucine rich repeat protein 2 involved_in IDA (PMID:26037928) UniProt PMID:26037928 NCBI chr 3:33,277,025...33,422,698
Ensembl chr 3:33,277,025...33,403,662 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 involved_in IDA (PMID:36586411) UniProt PMID:36586411 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G IRGM immunity related GTPase M involved_in IDA (PMID:30612879) UniProt PMID:30612879 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 involved_in IDA (PMID:36586411) UniProt PMID:36586411 NCBI chr  X:120,426,148...120,469,349
Ensembl chr  X:120,426,148...120,469,365 		JBrowse link
G MEFV MEFV innate immunity regulator, pyrin involved_in IMP (PMID:26347139) UniProt PMID:26347139 NCBI chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633 		JBrowse link
G MT-RNR2 mitochondrially encoded 16S rRNA involved_in IDA (PMID:32923762) UniProt PMID:32923762 NCBI chr MT:1,671...3,229
Ensembl chr MT:1,671...3,229 		JBrowse link
G NLRC3 NLR family CARD domain containing 3 involved_in IDA (PMID:25277106) UniProt PMID:25277106 NCBI chr16:3,539,033...3,577,403
Ensembl chr16:3,539,033...3,577,403 		JBrowse link
G NLRP2B NLR family pyrin domain containing 2B NOT|involved_in IMP (PMID:24871464) UniProt PMID:24871464 NCBI chr  X:57,677,067...57,680,260
Ensembl chr  X:57,677,067...57,680,260 		JBrowse link
G PYDC1 pyrin domain containing 1 NOT|involved_in IMP (PMID:24871464) UniProt PMID:24871464 NCBI chr16:31,215,962...31,217,135
Ensembl chr16:31,215,962...31,217,135 		JBrowse link
G PYDC2 pyrin domain containing 2 involved_in IMP (PMID:17339483), (PMID:24871464) UniProt PMID:17339483 PMID:24871464 NCBI chr 3:191,461,163...191,461,456
Ensembl chr 3:191,461,163...191,461,456 		JBrowse link
G SIRT2 sirtuin 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:38,878,555...38,899,618
Ensembl chr19:38,878,555...38,899,862 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within ISS
IEA
IMP		 (PMID:32514138) ARUK-UCL
Ensembl		 PMID:32514138 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
G TRIM22 tripartite motif containing 22 involved_in ISO (PMID:21048113) UniProt PMID:21048113 NCBI chr11:5,689,790...5,710,863
Ensembl chr11:5,689,610...5,737,089 		JBrowse link
G TRIM31 tripartite motif containing 31 involved_in IDA (PMID:27929086) UniProt PMID:27929086 NCBI chr 6:30,102,897...30,113,090
Ensembl chr 6:30,102,897...30,113,090 		JBrowse link
G TRIM65 tripartite motif containing 65 involved_in IDA (PMID:34512673) UniProt PMID:34512673 NCBI chr17:75,879,537...75,896,951
Ensembl chr17:75,880,335...75,896,951 		JBrowse link
G ZDHHC12 zinc finger DHHC-type palmitoyltransferase 12 involved_in IDA (PMID:36586411) UniProt PMID:36586411 NCBI chr 9:128,720,873...128,724,127
Ensembl chr 9:128,720,870...128,724,127 		JBrowse link
negative regulation of non-canonical inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IDA (PMID:37962578) UniProt PMID:37962578 NCBI chr  X:71,533,104...71,575,892
Ensembl chr  X:71,533,087...71,575,892 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERBIN erbb2 interacting protein involved_in IEA
IBA
IMP		 (PMID:16203728) Ensembl
GO_Central
UniProt		 PMID:16203728 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:65,926,575...66,082,546
Ensembl chr 5:65,883,128...66,082,546 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA
IMP		 (PMID:23991106) Ensembl
UniProt		 PMID:23991106 GO_REF:0000107 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G ZNRF4 zinc and ring finger 4 involved_in IDA (PMID:28656966) UniProt PMID:28656966 NCBI chr19:5,455,417...5,456,856
Ensembl chr19:5,455,417...5,456,856 		JBrowse link
negative regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUSP10 dual specificity phosphatase 10 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:221,701,424...221,742,089
Ensembl chr 1:221,701,424...221,742,089 		JBrowse link
G GRN granulin precursor involved_in IDA (PMID:12526812) UniProt PMID:12526812 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106 		JBrowse link
G INS insulin involved_in IDA (PMID:11443198) BHF-UCL PMID:11443198 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G RPS19 ribosomal protein S19 involved_in IDA (PMID:15750715) UniProt PMID:15750715 NCBI chr19:41,860,255...41,872,925
Ensembl chr19:41,860,255...41,872,925 		JBrowse link
G SLAMF8 SLAM family member 8 acts_upstream_of_or_within ISS UniProt GO_REF:0000024 NCBI chr 1:159,826,873...159,837,492
Ensembl chr 1:159,826,811...159,837,492 		JBrowse link
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QBP complement C1q binding protein involved_in IDA (PMID:19164550) UniProt PMID:19164550 NCBI chr17:5,432,777...5,439,155
Ensembl chr17:5,432,777...5,448,830 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA
IBA
IDA
IMP		 (PMID:18411269)
(PMID:21187438)		 Ensembl
GO_Central
UniProt		 PMID:18411269 PMID:21187438 GO_REF:0000033 GO_REF:0000107 NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714 		JBrowse link
G GPATCH3 G-patch domain containing 3 involved_in IEA
IBA
IMP		 (PMID:28414768) InterPro
GO_Central
UniProt		 PMID:28414768 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:26,890,488...26,900,467
Ensembl chr 1:26,890,488...26,900,467 		JBrowse link
G NLRX1 NLR family member X1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:119,168,334...119,184,016
Ensembl chr11:119,166,568...119,184,016 		JBrowse link
G NPLOC4 NPL4 homolog, ubiquitin recognition factor involved_in IMP (PMID:26471729) UniProt PMID:26471729 NCBI chr17:81,556,885...81,637,112
Ensembl chr17:81,556,887...81,648,465 		JBrowse link
G RNF125 ring finger protein 125 involved_in IDA (PMID:17460044), (PMID:26471729) UniProt PMID:17460044 PMID:26471729 NCBI chr18:32,018,825...32,088,144
Ensembl chr18:32,018,825...32,088,144 		JBrowse link
G SEC14L1 SEC14 like lipid binding 1 involved_in IMP
IBA		 (PMID:23843640) UniProt
GO_Central		 PMID:23843640 GO_REF:0000033 NCBI chr17:77,088,685...77,217,101
Ensembl chr17:77,088,749...77,217,101 		JBrowse link
G UFD1 ubiquitin recognition factor in ER associated degradation 1 involved_in IMP (PMID:26471729) UniProt PMID:26471729 NCBI chr22:19,449,911...19,479,193
Ensembl chr22:19,449,911...19,479,202 		JBrowse link
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MUC4 mucin 4, cell surface associated ISO RGD PMID:10232613 RGD:2303754 NCBI chr 3:195,746,771...195,811,929
Ensembl chr 3:195,746,765...195,811,973 		JBrowse link
negative regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor involved_in IDA (PMID:32818467) UniProt PMID:32818467 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G CD274 CD274 molecule involved_in IMP
IDA		 (PMID:28813410), (PMID:28813417)
(PMID:28813417)		 UniProt PMID:28813410 PMID:28813417 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G IL4I1 interleukin 4 induced 1 involved_in IDA (PMID:32818467) UniProt PMID:32818467 NCBI chr19:49,889,654...49,929,504
Ensembl chr19:49,889,654...49,929,539 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in IDA (PMID:37208329) UniProt PMID:37208329 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G PDCD1 programmed cell death 1 involved_in IDA (PMID:38377992) UniProt PMID:38377992 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
G UFL1 UFM1 specific ligase 1 involved_in IDA (PMID:38377992) UniProt PMID:38377992 NCBI chr 6:96,521,806...96,555,276
Ensembl chr 6:96,521,595...96,555,276 		JBrowse link
G USP5 ubiquitin specific peptidase 5 involved_in IDA (PMID:37208329) UniProt PMID:37208329 NCBI chr12:6,852,150...6,866,632
Ensembl chr12:6,852,148...6,866,632 		JBrowse link
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IMP
IEA		 (PMID:26599367) UniProt
Ensembl		 PMID:26599367 GO_REF:0000107 NCBI chr 8:8,783,354...8,893,630
Ensembl chr 8:8,783,354...8,893,630 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15220916) MGI PMID:15220916 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G TLR6 toll like receptor 6 involved_in IGI (PMID:22198949) ARUK-UCL PMID:22198949 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in NAS (PMID:15142865) BHF-UCL PMID:15142865 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
negative regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2RL1 F2R like trypsin receptor 1 involved_in IMP (PMID:19865078) UniProt PMID:19865078 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in IDA (PMID:15474016) BHF-UCL PMID:15474016 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:83,659,968...83,707,958
Ensembl chr 9:83,659,968...83,707,958 		JBrowse link
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638 		JBrowse link
G BPIFB1 BPI fold containing family B member 1 involved_in IDA
IBA		 (PMID:21900486) UniProt
GO_Central		 PMID:21900486 GO_REF:0000033 NCBI chr20:33,283,214...33,309,871
Ensembl chr20:33,273,480...33,309,871 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IDA (PMID:19948740) UniProt PMID:19948740 NCBI chr 9:121,567,074...121,785,530
Ensembl chr 9:121,567,057...121,785,530 		JBrowse link
G LILRA2 leukocyte immunoglobulin like receptor A2 involved_in IMP (PMID:22479404) UniProt PMID:22479404 NCBI chr19:54,572,988...54,590,287
Ensembl chr19:54,572,920...54,590,287 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IMP (PMID:28609714) UniProt PMID:28609714 NCBI chr 8:8,783,354...8,893,630
Ensembl chr 8:8,783,354...8,893,630 		JBrowse link
G MIR140 microRNA 140 involved_in IGI
IMP		 (PMID:30321456)
(PMID:30233718)		 ARUK-UCL PMID:30233718 PMID:30321456 NCBI chr16:69,933,081...69,933,180
Ensembl chr16:69,933,081...69,933,180 		JBrowse link
G MIR146A microRNA 146a involved_in IC (PMID:21329689) ARUK-UCL PMID:21329689 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450 		JBrowse link
G MIR149 microRNA 149 involved_in IMP (PMID:28260877) ARUK-UCL PMID:28260877 NCBI chr 2:240,456,001...240,456,089
Ensembl chr 2:240,456,001...240,456,089 		JBrowse link
G MIR200B microRNA 200b involved_in IDA (PMID:22522429) ARUK-UCL PMID:22522429 NCBI chr 1:1,167,104...1,167,198
Ensembl chr 1:1,167,104...1,167,198 		JBrowse link
G MIR200C microRNA 200c involved_in IDA (PMID:22522429) ARUK-UCL PMID:22522429 NCBI chr12:6,963,699...6,963,766
Ensembl chr12:6,963,699...6,963,766 		JBrowse link
G MIR20A microRNA 20a involved_in IDA (PMID:29653364) ARUK-UCL PMID:29653364 NCBI chr13:91,351,065...91,351,135
Ensembl chr13:91,351,065...91,351,135 		JBrowse link
G MIR708 microRNA 708 involved_in IMP (PMID:31599428) ARUK-UCL PMID:31599428 NCBI chr11:79,402,022...79,402,109
Ensembl chr11:79,402,022...79,402,109 		JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in IMP (PMID:18511497) BHF-UCL PMID:18511497 NCBI chr17:40,092,793...40,100,589
Ensembl chr17:40,092,793...40,100,589 		JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:205,976,740...206,003,395
Ensembl chr 1:205,976,740...206,003,461 		JBrowse link
G SQSTM1 sequestosome 1 involved_in IDA (PMID:31281713) UniProt PMID:31281713 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 involved_in IDA (PMID:28898289) UniProt PMID:28898289 NCBI chr 7:27,739,373...27,829,767
Ensembl chr 7:27,739,331...27,844,564 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IDA (PMID:19412184) UniProt PMID:19412184 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TMED7-TICAM2 TMED7-TICAM2 readthrough involved_in IDA (PMID:19412184) UniProt PMID:19412184 NCBI chr 5:115,578,496...115,626,036
Ensembl chr 5:115,578,642...115,626,161 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in NAS (PMID:15142865) BHF-UCL PMID:15142865 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
G TRIM32 tripartite motif containing 32 involved_in IDA (PMID:28898289) UniProt PMID:28898289 NCBI chr 9:116,687,305...116,701,299
Ensembl chr 9:116,687,305...116,701,300 		JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
negative regulation of toll-like receptor 6 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR210 microRNA 210 involved_in IMP (PMID:38742642) FlyBase PMID:38742642 NCBI chr11:568,089...568,198
Ensembl chr11:568,089...568,198 		JBrowse link
negative regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LILRA4 leukocyte immunoglobulin like receptor A4 involved_in IMP (PMID:16735691) UniProt PMID:16735691 NCBI chr19:54,333,185...54,339,162
Ensembl chr19:54,333,185...54,339,162 		JBrowse link
negative regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRAMD4 GRAM domain containing 4 involved_in IEA
IBA
ISS		 Ensembl
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr22:46,575,744...46,682,756
Ensembl chr22:46,576,012...46,679,790 		JBrowse link
G LILRA4 leukocyte immunoglobulin like receptor A4 involved_in IMP (PMID:16735691) UniProt PMID:16735691 NCBI chr19:54,333,185...54,339,162
Ensembl chr19:54,333,185...54,339,162 		JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in IDA (PMID:14716310) UniProt PMID:14716310 NCBI chr 1:40,071,461...40,097,252
Ensembl chr 1:40,072,710...40,097,260 		JBrowse link
G PTPRS protein tyrosine phosphatase receptor type S involved_in IMP (PMID:26231120) UniProt PMID:26231120 NCBI chr19:5,205,508...5,340,812
Ensembl chr19:5,158,495...5,340,812 		JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:205,976,740...206,003,395
Ensembl chr 1:205,976,740...206,003,461 		JBrowse link
negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB2 arrestin beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499 		JBrowse link
G CACTIN cactin, spliceosome C complex subunit involved_in IDA (PMID:20829348) UniProt PMID:20829348 NCBI chr19:3,610,645...3,626,790
Ensembl chr19:3,610,645...3,626,815 		JBrowse link
G GPR108 G protein-coupled receptor 108 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr19:6,729,914...6,737,580
Ensembl chr19:6,729,914...6,737,580 		JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:7,312,661...7,315,360
Ensembl chr17:7,311,324...7,315,564 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 involved_in ISS
IEA		 (PMID:12150927) BHF-UCL
Ensembl		 PMID:12150927 GO_REF:0000107 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622 		JBrowse link
G IRF4 interferon regulatory factor 4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443 		JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:27,365,961...27,472,790
Ensembl chr11:27,365,961...27,472,790 		JBrowse link
G LRRC14 leucine rich repeat containing 14 involved_in IDA
IBA		 (PMID:27426725) UniProt
GO_Central		 PMID:27426725 GO_REF:0000033 NCBI chr 8:144,517,992...144,525,178
Ensembl chr 8:144,517,992...144,525,172 		JBrowse link
G MIR140 microRNA 140 ISO RGD PMID:31376096 RGD:329337378 NCBI chr16:69,933,081...69,933,180
Ensembl chr16:69,933,081...69,933,180 		JBrowse link
G MIR17 microRNA 17 involved_in IMP (PMID:26041742) ARUK-UCL PMID:26041742 NCBI chr13:91,350,605...91,350,688
Ensembl chr13:91,350,605...91,350,688 		JBrowse link
G MIR19A microRNA 19a involved_in IMP (PMID:26041742) ARUK-UCL PMID:26041742 NCBI chr13:91,350,891...91,350,972
Ensembl chr13:91,350,891...91,350,972 		JBrowse link
G NFKBIL1 NFKB inhibitor like 1 involved_in IDA
IBA		 (PMID:20829348) UniProt
GO_Central		 PMID:20829348 GO_REF:0000033 NCBI chr 6:31,546,851...31,558,829
Ensembl chr 6:31,546,870...31,558,829 		JBrowse link
G NLRP2B NLR family pyrin domain containing 2B involved_in IMP (PMID:24871464) UniProt PMID:24871464 NCBI chr  X:57,677,067...57,680,260
Ensembl chr  X:57,677,067...57,680,260 		JBrowse link
G NLRP6 NLR family pyrin domain containing 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:278,407...285,388
Ensembl chr11:278,407...285,388 		JBrowse link
G OTUD4 OTU deubiquitinase 4 involved_in IEA
IBA
IDA		 (PMID:29395066) Ensembl
GO_Central
UniProt		 PMID:29395066 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:145,133,650...145,180,589
Ensembl chr 4:145,110,838...145,180,589 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:2,538,021...2,603,188
Ensembl chr16:2,537,979...2,603,190 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) UniProt PMID:20728433 NCBI chr10:96,593,315...96,720,514
Ensembl chr10:96,593,315...96,720,514 		JBrowse link
G RNF115 ring finger protein 115 involved_in IDA (PMID:35343654) UniProt PMID:35343654 NCBI chr 1:145,738,868...145,824,095
Ensembl chr 1:145,738,868...145,824,095 		JBrowse link
G SMPDL3B sphingomyelin phosphodiesterase acid like 3B involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:27,935,000...27,959,152
Ensembl chr 1:27,935,000...27,959,157 		JBrowse link
G TRIM22 tripartite motif containing 22 involved_in ISO (PMID:18345001) UniProt PMID:18345001 NCBI chr11:5,689,790...5,710,863
Ensembl chr11:5,689,610...5,737,089 		JBrowse link
G TYRO3 TYRO3 protein tyrosine kinase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:41,559,212...41,583,589
Ensembl chr15:41,557,675...41,583,589 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in IDA (PMID:35343654) UniProt PMID:35343654 NCBI chr17:1,344,275...1,400,222
Ensembl chr17:1,344,275...1,400,222 		JBrowse link
negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAR adenosine deaminase RNA specific acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:154,582,057...154,627,997
Ensembl chr 1:154,581,695...154,628,013 		JBrowse link
G CACTIN cactin, spliceosome C complex subunit involved_in IMP (PMID:20829348) UniProt PMID:20829348 NCBI chr19:3,610,645...3,626,790
Ensembl chr19:3,610,645...3,626,815 		JBrowse link
G CNOT7 CCR4-NOT transcription complex subunit 7 involved_in IMP (PMID:23386060) UniProt PMID:23386060 NCBI chr 8:17,224,966...17,246,857
Ensembl chr 8:17,224,966...17,246,878 		JBrowse link
G DCST1 DC-STAMP domain containing 1 involved_in IMP (PMID:27782195) UniProt PMID:27782195 NCBI chr 1:155,033,806...155,050,930
Ensembl chr 1:155,033,824...155,050,930 		JBrowse link
G EIF4E2 eukaryotic translation initiation factor 4E family member 2 involved_in IDA (PMID:35878012) UniProt PMID:35878012 NCBI chr 2:232,550,689...232,583,644
Ensembl chr 2:232,550,659...232,583,644 		JBrowse link
G GIGYF2 GRB10 interacting GYF protein 2 involved_in IDA (PMID:35878012) UniProt PMID:35878012 NCBI chr 2:232,697,331...232,860,605
Ensembl chr 2:232,697,299...232,860,605 		JBrowse link
G ISG15 ISG15 ubiquitin like modifier involved_in IMP (PMID:28724761) ARUK-UCL PMID:28724761 NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540 		JBrowse link
G METTL3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit involved_in IMP (PMID:30559377) UniProt PMID:30559377 NCBI chr14:21,498,138...21,511,340
Ensembl chr14:21,498,133...21,511,342 		JBrowse link
G MIR21 microRNA 21 involved_in IDA (PMID:23633945) BHF-UCL PMID:23633945 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MMP12 matrix metallopeptidase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982 		JBrowse link
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 involved_in IMP (PMID:23399697) UniProt PMID:23399697 NCBI chr 1:20,499,448...20,508,151
Ensembl chr 1:20,499,448...20,508,151 		JBrowse link
G NLRC5 NLR family CARD domain containing 5 involved_in IDA
IBA
IEA		 (PMID:20434986) UniProt
GO_Central
Ensembl		 PMID:20434986 GO_REF:0000033 GO_REF:0000107 NCBI chr16:56,989,557...57,083,520
Ensembl chr16:56,989,485...57,083,531 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IMP (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chr12:112,906,962...112,933,219
Ensembl chr12:112,905,856...112,933,219 		JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 involved_in IMP (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chr12:112,938,474...112,973,251
Ensembl chr12:112,938,051...112,976,460 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA
IMP		 (PMID:11909529) Ensembl
UniProt		 PMID:11909529 GO_REF:0000107 NCBI chr18:12,785,478...12,884,237
Ensembl chr18:12,785,478...12,929,643 		JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in IEA
IDA		 (PMID:29670289) Ensembl
UniProt		 PMID:29670289 GO_REF:0000107 NCBI chr20:36,889,773...36,951,708
Ensembl chr20:36,890,229...36,951,893 		JBrowse link
G SMIM30 small integral membrane protein 30 involved_in IMP
IBA		 (PMID:37656786) UniProt
GO_Central		 PMID:37656786 GO_REF:0000033 NCBI chr 7:113,116,718...113,118,554
Ensembl chr 7:113,116,718...113,118,560 		JBrowse link
G STAT2 signal transducer and activator of transcription 2 involved_in IMP (PMID:28165510) UniProt PMID:28165510 NCBI chr12:56,341,597...56,360,107
Ensembl chr12:56,341,597...56,360,203 		JBrowse link
G TREX1 three prime repair exonuclease 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645 		JBrowse link
G TTLL12 tubulin tyrosine ligase like 12 involved_in IMP (PMID:28011935) UniProt PMID:28011935 NCBI chr22:43,166,622...43,187,134
Ensembl chr22:43,166,622...43,187,134 		JBrowse link
G USP18 ubiquitin specific peptidase 18 involved_in IDA (PMID:28165510) UniProt PMID:28165510 NCBI chr22:18,150,170...18,177,397
Ensembl chr22:18,149,843...18,177,397 		JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein F2 involved_in IMP (PMID:30559377) UniProt PMID:30559377 NCBI chr 1:28,736,624...28,769,775
Ensembl chr 1:28,736,621...28,769,775 		JBrowse link
G YTHDF3 YTH N6-methyladenosine RNA binding protein F3 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:63,168,553...63,212,788
Ensembl chr 8:63,168,553...63,212,786 		JBrowse link
negative regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG1 arginase 1 involved_in IMP (PMID:16709924) UniProt PMID:16709924 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332 		JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 involved_in IDA (PMID:11679576) UniProt PMID:11679576 NCBI chr16:4,425,868...4,456,775
Ensembl chr16:4,425,805...4,456,775 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 involved_in NAS (PMID:21268089) BHF-UCL PMID:21268089 NCBI chr19:50,376,457...50,383,388
Ensembl chr19:50,329,653...50,383,388 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in NAS (PMID:21268089) BHF-UCL PMID:21268089 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033 		JBrowse link
G OTOP1 otopetrin 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:4,188,726...4,226,929
Ensembl chr 4:4,188,726...4,226,929 		JBrowse link
G PARP14 poly(ADP-ribose) polymerase family member 14 involved_in IMP
IBA
IEA		 (PMID:27796300) UniProt
GO_Central
Ensembl		 PMID:27796300 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:122,680,839...122,730,840
Ensembl chr 3:122,680,839...122,730,840 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in IMP (PMID:21268089) BHF-UCL PMID:21268089 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in
NOT|involved_in		 IEA
IMP
IDA
ISS		 (PMID:12138178) Ensembl
UniProt		 PMID:12138178 GO_REF:0000024 GO_REF:0000107 NCBI chr18:12,785,478...12,884,237
Ensembl chr18:12,785,478...12,929,643 		JBrowse link
NLRP1 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLRP1 NLR family pyrin domain containing 1 involved_in IMP
IDA		 (PMID:27662089), (PMID:31484767)
(PMID:22665479), (PMID:33243852), (PMID:33420028), (PMID:33420033), (PMID:33852854), (PMID:35594856)		 UniProt PMID:22665479 PMID:27662089 PMID:31484767 PMID:33243852 PMID:33420028 More... NCBI chr17:5,501,396...5,584,509
Ensembl chr17:5,499,415...5,619,424 		JBrowse link
NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAT1 alpha tubulin acetyltransferase 1 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 6:30,626,874...30,646,821
Ensembl chr 6:30,626,842...30,646,823 		JBrowse link
G GKN2 gastrokine 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:68,945,232...68,952,893
Ensembl chr 2:68,945,232...68,952,893 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:21,764,955...21,774,706
Ensembl chr12:21,764,955...21,775,600 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
IDA
ISO		 (PMID:17483456), (PMID:23582325), (PMID:25686105), (PMID:27043286), (PMID:27432880), (PMID:28465465), (PMID:28656979), (PMID:28943315), (PMID:30487600), (PMID:31189953), (PMID:33231615), (PMID:34554188), (PMID:34615873), (PMID:35114687), (PMID:35254907), (PMID:35559676), (PMID:36442502), (PMID:39173637)
(PMID:22753929)		 Ensembl
UniProt
MGI		 PMID:17483456 PMID:22753929 PMID:23582325 PMID:25686105 PMID:27043286 More... GO_REF:0000107 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IDA (PMID:27432880) UniProt PMID:27432880 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G SIRT2 sirtuin 2 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr19:38,878,555...38,899,618
Ensembl chr19:38,878,555...38,899,862 		JBrowse link
NLRP6 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLRP6 NLR family pyrin domain containing 6 involved_in IDA
IEA		 (PMID:30674671), (PMID:31932628), (PMID:34678144) UniProt
Ensembl		 PMID:30674671 PMID:31932628 PMID:34678144 GO_REF:0000107 NCBI chr11:278,407...285,388
Ensembl chr11:278,407...285,388 		JBrowse link
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYLD CYLD lysine 63 deubiquitinase involved_in TAS Reactome Reactome:R-HSA-168638 NCBI chr16:50,742,086...50,801,935
Ensembl chr16:50,742,050...50,801,935 		JBrowse link
G ITCH itchy E3 ubiquitin protein ligase involved_in TAS Reactome Reactome:R-HSA-168638 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,235...34,511,773 		JBrowse link
G MAP2K6 mitogen-activated protein kinase kinase 6 involved_in TAS Reactome Reactome:R-HSA-168638 NCBI chr17:69,414,697...69,553,865
Ensembl chr17:69,414,697...69,553,865 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in TAS Reactome Reactome:R-HSA-168638 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G RNF34 ring finger protein 34 involved_in IMP (PMID:25012219) UniProt PMID:25012219 NCBI chr12:121,400,118...121,424,348
Ensembl chr12:121,400,083...121,430,623 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in TAS Reactome Reactome:R-HSA-168638 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFKBIA NFKB inhibitor alpha acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in IDA
IEA		 (PMID:11058605), (PMID:12791997), (PMID:12796777) UniProt
Ensembl		 PMID:11058605 PMID:12791997 PMID:12796777 GO_REF:0000107 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IDA
IEA		 (PMID:29452636), (PMID:30279485) UniProt
Ensembl		 PMID:29452636 PMID:30279485 GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IDA (PMID:29452636) UniProt PMID:29452636 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INAVA innate immunity activator involved_in IMP (PMID:28436939) UniProt PMID:28436939 NCBI chr 1:200,891,531...200,915,742
Ensembl chr 1:200,891,048...200,915,742 		JBrowse link
G IRF5 interferon regulatory factor 5 involved_in IDA (PMID:22412986) BHF-UCL PMID:22412986 NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038 		JBrowse link
G IRGM immunity related GTPase M involved_in IMP (PMID:25891078) UniProt PMID:25891078 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736 		JBrowse link
G LACC1 laccase domain containing 1 involved_in IDA (PMID:31875558) UniProt PMID:31875558 NCBI chr13:43,879,178...43,893,932
Ensembl chr13:43,879,284...43,893,932 		JBrowse link
G NFKBIA NFKB inhibitor alpha acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in		 IDA (PMID:12527755)
(PMID:12626759), (PMID:15044951), (PMID:17355968), (PMID:23806334), (PMID:31649195)		 MGI
UniProt		 PMID:12527755 PMID:12626759 PMID:15044951 PMID:17355968 PMID:23806334 More... NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G OTULIN OTU deubiquitinase with linear linkage specificity involved_in IMP (PMID:23806334) UniProt PMID:23806334 NCBI chr 5:14,664,718...14,716,525
Ensembl chr 5:14,664,664...14,716,529 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit acts_upstream_of_or_within IDA (PMID:12527755) MGI PMID:12527755 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IDA		 (PMID:11894098)
(PMID:16824733), (PMID:17355968), (PMID:17562858), (PMID:23806334), (PMID:28545134), (PMID:29452636), (PMID:30026309), (PMID:30279485), (PMID:30478312)		 Ensembl
MGI
UniProt		 PMID:11894098 PMID:16824733 PMID:17355968 PMID:17562858 PMID:23806334 More... GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IDA (PMID:19667203), (PMID:22607974), (PMID:29452636) UniProt PMID:19667203 PMID:22607974 PMID:29452636 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC097637.1 novel twinfilin, actin-binding protein, homolog 2 (Drosophila) (TWF2) and toll-like receptor 9 (TLR9) protein involved_in IEA UniProt GO_REF:0000117 Ensembl chr 3:52,221,081...52,231,190 JBrowse link
G AIM2 absent in melanoma 2 involved_in NAS (PMID:29247998) ComplexPortal PMID:29247998 NCBI chr 1:159,055,051...159,147,132
Ensembl chr 1:159,056,129...159,187,843 		JBrowse link
G CASP1 caspase 1 involved_in NAS (PMID:21918512), (PMID:22258606), (PMID:29196474), (PMID:29247998) ComplexPortal PMID:21918512 PMID:22258606 PMID:29196474 PMID:29247998 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IDA (PMID:23258413) UniProt PMID:23258413 NCBI chr 6:73,423,711...73,452,297
Ensembl chr 6:73,413,515...73,452,297 		JBrowse link
G CLEC4E C-type lectin domain family 4 member E involved_in IMP (PMID:24101491) UniProt PMID:24101491 NCBI chr12:8,533,275...8,540,905
Ensembl chr12:8,533,305...8,540,905 		JBrowse link
G INAVA innate immunity activator involved_in IMP (PMID:28436939) UniProt PMID:28436939 NCBI chr 1:200,891,531...200,915,742
Ensembl chr 1:200,891,048...200,915,742 		JBrowse link
G LACC1 laccase domain containing 1 involved_in IDA (PMID:28593945), (PMID:31875558) UniProt PMID:28593945 PMID:31875558 NCBI chr13:43,879,178...43,893,932
Ensembl chr13:43,879,284...43,893,932 		JBrowse link
G MEFV MEFV innate immunity regulator, pyrin involved_in NAS (PMID:29196474) ComplexPortal PMID:29196474 NCBI chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633 		JBrowse link
G NAIP NLR family apoptosis inhibitory protein involved_in NAS (PMID:21918512) ComplexPortal PMID:21918512 NCBI chr 5:70,968,166...71,025,339
Ensembl chr 5:70,968,166...71,025,339 		JBrowse link
G NLRC4 NLR family CARD domain containing 4 involved_in NAS (PMID:21918512) ComplexPortal PMID:21918512 NCBI chr 2:32,224,449...32,265,743
Ensembl chr 2:32,224,453...32,265,732 		JBrowse link
G NLRP1 NLR family pyrin domain containing 1 involved_in NAS (PMID:22258606) ComplexPortal PMID:22258606 NCBI chr17:5,501,396...5,584,509
Ensembl chr17:5,499,415...5,619,424 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in NAS (PMID:22258606) ComplexPortal PMID:22258606 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in IDA (PMID:31649195) UniProt PMID:31649195 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in IDA (PMID:31649195) UniProt PMID:31649195 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in NAS (PMID:21918512), (PMID:22258606), (PMID:29196474), (PMID:29247998) ComplexPortal PMID:21918512 PMID:22258606 PMID:29196474 PMID:29247998 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G RNF144A ring finger protein 144A involved_in IDA (PMID:37955227) UniProt PMID:37955227 NCBI chr 2:6,917,412...7,076,367
Ensembl chr 2:6,917,412...7,068,286 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IDA (PMID:23910378) UniProt PMID:23910378 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
G TLR7 toll like receptor 7 involved_in IEA UniProt GO_REF:0000117 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
G TLR8 toll like receptor 8 involved_in IEA UniProt GO_REF:0000117 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169 		JBrowse link
G TLR9 toll like receptor 9 involved_in IEA UniProt GO_REF:0000117 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
positive regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GBP2 guanylate binding protein 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:89,106,132...89,126,114
Ensembl chr 1:89,106,132...89,150,456 		JBrowse link
G GBP5 guanylate binding protein 5 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:89,256,189...89,272,860
Ensembl chr 1:89,256,189...89,272,860 		JBrowse link
positive regulation of antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:18167348) MGI PMID:18167348 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
positive regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KLK3 kallikrein related peptidase 3 involved_in IDA (PMID:18714013) UniProt PMID:18714013 NCBI chr19:50,854,915...50,860,764
Ensembl chr19:50,854,915...50,860,764 		JBrowse link
G KLK5 kallikrein related peptidase 5 involved_in IMP (PMID:17012259) UniProt PMID:17012259 NCBI chr19:50,943,303...50,953,038
Ensembl chr19:50,943,303...50,953,093 		JBrowse link
G KLK7 kallikrein related peptidase 7 involved_in IMP (PMID:17012259) UniProt PMID:17012259 NCBI chr19:50,976,468...50,984,064
Ensembl chr19:50,976,468...50,984,099 		JBrowse link
G PGC progastricsin involved_in IMP (PMID:12759353) UniProt PMID:12759353 NCBI chr 6:41,736,711...41,747,397
Ensembl chr 6:41,736,711...41,754,109 		JBrowse link
positive regulation of antifungal innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G5 phospholipase A2 group V involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:20,028,408...20,091,911
Ensembl chr 1:20,028,179...20,091,911 		JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:47,354,860...47,378,547
Ensembl chr11:47,354,860...47,409,369 		JBrowse link
G TRIM62 tripartite motif containing 62 involved_in IDA
IEA		 (PMID:26488816) UniProt
Ensembl		 PMID:26488816 GO_REF:0000107 NCBI chr 1:33,145,399...33,182,043
Ensembl chr 1:33,145,399...33,182,059 		JBrowse link
positive regulation of antimicrobial humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in IDA (PMID:23610393) UniProt PMID:23610393 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638 		JBrowse link
G CAMP cathelicidin antimicrobial peptide ISO RGD PMID:18227173 RGD:438738460 NCBI chr 3:48,223,495...48,225,485
Ensembl chr 3:48,223,347...48,225,491 		JBrowse link
positive regulation of antimicrobial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL17A interleukin 17A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL17F interleukin 17F involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:52,236,681...52,245,689
Ensembl chr 6:52,236,681...52,245,689 		JBrowse link
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15692051) MGI PMID:15692051 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
positive regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase involved_in IDA (PMID:25704810) UniProt PMID:25704810 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in IDA (PMID:37832545) UniProt PMID:37832545 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MARCHF5 membrane associated ring-CH-type finger 5 involved_in IDA (PMID:37916870) UniProt PMID:37916870 NCBI chr10:92,291,167...92,353,964
Ensembl chr10:92,291,167...92,353,964 		JBrowse link
G RNF39 ring finger protein 39 involved_in IDA (PMID:39255680) UniProt PMID:39255680 NCBI chr 6:30,070,270...30,075,769
Ensembl chr 6:30,070,266...30,075,849 		JBrowse link
G SLC19A1 solute carrier family 19 member 1 involved_in IMP (PMID:36745868) UniProt PMID:36745868 NCBI chr21:45,502,517...45,563,025
Ensembl chr21:45,493,572...45,573,365 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 involved_in IDA (PMID:37832545) UniProt PMID:37832545 NCBI chr22:39,399,780...39,437,132
Ensembl chr22:39,399,778...39,437,060 		JBrowse link
G ZDHHC9 zinc finger DHHC-type palmitoyltransferase 9 involved_in IDA (PMID:37802025) UniProt PMID:37802025 NCBI chr  X:129,803,288...129,843,886
Ensembl chr  X:129,803,288...129,843,909 		JBrowse link
positive regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR520B microRNA 520b involved_in IDA (PMID:20574151) ARUK-UCL PMID:20574151 NCBI chr19:53,701,227...53,701,287
Ensembl chr19:53,701,227...53,701,287 		JBrowse link
G MIR520E microRNA 520e involved_in IDA (PMID:20574151) ARUK-UCL PMID:20574151 NCBI chr19:53,675,711...53,675,797
Ensembl chr19:53,675,711...53,675,797 		JBrowse link
positive regulation of defense response to bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYBA cytochrome b-245 alpha chain involved_in IDA (PMID:22423966) UniProt PMID:22423966 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G EMILIN1 elastin microfibril interfacer 1 involved_in IDA (PMID:17988845) ComplexPortal PMID:17988845 NCBI chr 2:27,078,615...27,086,403
Ensembl chr 2:27,078,615...27,086,403 		JBrowse link
G EMILIN2 elastin microfibril interfacer 2 involved_in IDA (PMID:17988845) ComplexPortal PMID:17988845 NCBI chr18:2,846,232...2,916,003
Ensembl chr18:2,847,006...2,916,003 		JBrowse link
G GRN granulin precursor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G LGALS9 galectin 9 involved_in ISO (PMID:20937702) UniProt PMID:20937702 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G MMRN2 multimerin 2 involved_in IEA
ISO		 Ensembl
ComplexPortal		 GO_REF:0000107 GO_REF:0000114 NCBI chr10:86,935,540...86,957,615
Ensembl chr10:86,935,540...86,969,481 		JBrowse link
G NLRP10 NLR family pyrin domain containing 10 involved_in IMP (PMID:28766990) UniProt PMID:28766990 NCBI chr11:7,957,537...7,965,447
Ensembl chr11:7,957,537...7,965,447 		JBrowse link
G RAB34 RAB34, member RAS oncogene family involved_in ISO (PMID:23197834) ParkinsonsUK-UCL PMID:23197834 NCBI chr17:28,714,281...28,718,428
Ensembl chr17:28,714,281...28,718,429 		JBrowse link
G SIGLEC16 sialic acid binding Ig like lectin 16 (gene/pseudogene) involved_in IDA (PMID:28100677) UniProt PMID:28100677 NCBI chr19:49,969,664...49,975,814
Ensembl chr19:49,969,600...49,975,819 		JBrowse link
G UNC13B unc-13 homolog B involved_in ISO (PMID:23197834) ParkinsonsUK-UCL PMID:23197834 NCBI chr 9:35,162,009...35,405,335
Ensembl chr 9:35,161,992...35,405,338 		JBrowse link
positive regulation of defense response to virus by host term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIM2 absent in melanoma 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:159,055,051...159,147,132
Ensembl chr 1:159,056,129...159,187,843 		JBrowse link
G APOBEC3F apolipoprotein B mRNA editing enzyme catalytic subunit 3F involved_in IDA (PMID:17121840) HGNC-UCL PMID:17121840 NCBI chr22:39,040,864...39,055,972
Ensembl chr22:39,040,604...39,055,972 		JBrowse link
G APOBEC3G apolipoprotein B mRNA editing enzyme catalytic subunit 3G involved_in IDA (PMID:17121840) HGNC-UCL PMID:17121840 NCBI chr22:39,077,005...39,087,743
Ensembl chr22:39,077,067...39,087,743 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IEA
IBA
IDA
IMP		 (PMID:23929945), (PMID:24077100), (PMID:26046437)
(PMID:23258413)		 Ensembl
GO_Central
UniProt		 PMID:23258413 PMID:23929945 PMID:24077100 PMID:26046437 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:73,423,711...73,452,297
Ensembl chr 6:73,413,515...73,452,297 		JBrowse link
G CREB3 cAMP responsive element binding protein 3 involved_in IDA (PMID:20091349) UniProt PMID:20091349 NCBI chr 9:35,732,666...35,736,999
Ensembl chr 9:35,732,598...35,736,999 		JBrowse link
G DTX3L deltex E3 ubiquitin ligase 3L involved_in IGI (PMID:26479788) UniProt PMID:26479788 NCBI chr 3:122,564,338...122,575,203
Ensembl chr 3:122,564,338...122,575,203 		JBrowse link
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISS UniProt GO_REF:0000024 NCBI chr15:39,934,115...40,035,591
Ensembl chr15:39,934,115...40,035,591 		JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor involved_in IMP (PMID:22483866) UniProt PMID:22483866 NCBI chr10:49,434,881...49,539,538
Ensembl chr10:49,454,168...49,539,538 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 involved_in IDA (PMID:20628368) UniProt PMID:20628368 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G IL12B interleukin 12B involved_in ISS
IEA
IDA		 (PMID:12421946) BHF-UCL
Ensembl		 PMID:12421946 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL12RB1 interleukin 12 receptor subunit beta 1 involved_in IDA
ISS		 (PMID:12421946) BHF-UCL PMID:12421946 GO_REF:0000024 NCBI chr19:18,058,995...18,098,816
Ensembl chr19:18,058,995...18,098,944 		JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA
IBA
IDA
ISS		 (PMID:12421946) Ensembl
GO_Central
BHF-UCL		 PMID:12421946 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410 		JBrowse link
G IL23R interleukin 23 receptor involved_in IDA
ISS		 (PMID:12421946) BHF-UCL PMID:12421946 GO_REF:0000024 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979 		JBrowse link
G IL27 interleukin 27 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051 		JBrowse link
G IL4 interleukin 4 ISO RGD PMID:9721086 RGD:8142392 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in
acts_upstream_of_or_within		 IDA
ISO
IMP		 (PMID:16127453), (PMID:20628368)
(PMID:18780793)
(PMID:19609254)		 BHF-UCL
MGI
UniProt		 PMID:16127453 PMID:18780793 PMID:19609254 PMID:20628368 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123 		JBrowse link
G PARP9 poly(ADP-ribose) polymerase family member 9 involved_in IGI (PMID:26479788) UniProt PMID:26479788 NCBI chr 3:122,527,924...122,564,784
Ensembl chr 3:122,527,924...122,564,577 		JBrowse link
G PML PML nuclear body scaffold involved_in IMP (PMID:16873256), (PMID:16873257) UniProt PMID:16873256 PMID:16873257 NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827 		JBrowse link
G PQBP1 polyglutamine binding protein 1 involved_in IDA (PMID:26046437) UniProt PMID:26046437 NCBI chr  X:48,897,930...48,903,143
Ensembl chr  X:48,890,197...48,903,402 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G RIGI RNA sensor RIG-I involved_in IMP (PMID:19609254) UniProt PMID:19609254 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,348 		JBrowse link
G SELENOK selenoprotein K involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,884,417...53,891,859
Ensembl chr 3:53,884,417...53,891,885 		JBrowse link
G SIN3A SIN3 transcription regulator family member A involved_in IMP (PMID:22783022) BHF-UCL PMID:22783022 NCBI chr15:75,369,379...75,455,815
Ensembl chr15:75,369,379...75,455,842 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 involved_in IGI
IMP		 (PMID:26479788) UniProt PMID:26479788 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IMP (PMID:18818105) BHF-UCL PMID:18818105 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
G TOMM70 translocase of outer mitochondrial membrane 70 involved_in IDA (PMID:20628368) UniProt PMID:20628368 NCBI chr 3:100,363,431...100,401,089
Ensembl chr 3:100,363,431...100,401,089 		JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 involved_in IDA (PMID:23066157) CACAO PMID:23066157 NCBI chr 6:111,555,381...111,605,878
Ensembl chr 6:111,555,381...111,606,906 		JBrowse link
G TREML4 triggering receptor expressed on myeloid cells like 4 involved_in ISO (PMID:25848864) UniProt PMID:25848864 NCBI chr 6:41,228,349...41,238,882
Ensembl chr 6:41,228,339...41,238,882 		JBrowse link
G TRIM22 tripartite motif containing 22 involved_in IDA (PMID:36159777) UniProt PMID:36159777 NCBI chr11:5,689,790...5,710,863
Ensembl chr11:5,689,610...5,737,089 		JBrowse link
G TRIM44 tripartite motif containing 44 involved_in IDA (PMID:23460740) BHF-UCL PMID:23460740 NCBI chr11:35,662,775...35,818,007
Ensembl chr11:35,662,775...35,818,007 		JBrowse link
G TRIM6 tripartite motif containing 6 involved_in IMP (PMID:24882218) UniProt PMID:24882218 NCBI chr11:5,596,111...5,612,952
Ensembl chr11:5,596,109...5,612,958 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IDA (PMID:23355615) UniProt PMID:23355615 NCBI chr 1:37,474,580...37,484,377
Ensembl chr 1:37,474,580...37,484,377 		JBrowse link
G ZDHHC1 zinc finger DHHC-type containing 1 involved_in IMP
IEA		 (PMID:25299331) UniProt
Ensembl		 PMID:25299331 GO_REF:0000107 NCBI chr16:67,394,152...67,416,477
Ensembl chr16:67,394,152...67,416,833 		JBrowse link
G ZDHHC11 zinc finger DHHC-type containing 11 involved_in IMP (PMID:29429998) UniProt PMID:29429998 NCBI chr 5:795,605...860,563
Ensembl chr 5:795,605...858,973 		JBrowse link
G ZDHHC11B zinc finger DHHC-type containing 11B involved_in ISO (PMID:29429998) UniProt PMID:29429998 NCBI chr 5:710,355...784,729
Ensembl chr 5:710,355...784,729 		JBrowse link
positive regulation of immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD40LG CD40 ligand ISO RGD PMID:19016771 RGD:2313413 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G GSDME gasdermin E involved_in IDA (PMID:32188940) UniProt PMID:32188940 NCBI chr 7:24,698,355...24,795,539
Ensembl chr 7:24,698,355...24,757,940 		JBrowse link
G HRG histidine rich glycoprotein involved_in IDA
IBA		 (PMID:21215706) UniProt
GO_Central		 PMID:21215706 GO_REF:0000033 NCBI chr 3:186,666,014...186,678,234
Ensembl chr 3:186,660,216...186,678,234 		JBrowse link
G ULBP1 UL16 binding protein 1 acts_upstream_of_or_within ISO (PMID:12645935) MGI PMID:12645935 NCBI chr 6:149,963,943...149,973,715
Ensembl chr 6:149,963,943...149,973,715 		JBrowse link
positive regulation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM8 ADAM metallopeptidase domain 8 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:133,262,423...133,276,868
Ensembl chr10:133,262,420...133,276,868 		JBrowse link
G AKIRIN2 akirin 2 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:87,674,860...87,702,233
Ensembl chr 6:87,674,860...87,702,233 		JBrowse link
G CARD9 caspase recruitment domain family member 9 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:136,363,956...136,373,669
Ensembl chr 9:136,363,956...136,373,681 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 involved_in TAS (PMID:21148810) BHF-UCL PMID:21148810 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CD1D CD1d molecule involved_in TAS (PMID:14500461) UniProt PMID:14500461 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A involved_in IDA (PMID:38016475) UniProt PMID:38016475 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G DHX9 DExH-box helicase 9 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:182,839,347...182,887,982
Ensembl chr 1:182,839,347...182,887,982 		JBrowse link
G EREG epiregulin involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749 		JBrowse link
G FADD Fas associated via death domain involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390 		JBrowse link
G FPR2 formyl peptide receptor 2 involved_in IDA (PMID:25505240) ARUK-UCL PMID:25505240 NCBI chr19:51,761,180...51,770,531
Ensembl chr19:51,752,026...51,770,531 		JBrowse link
G GBP5 guanylate binding protein 5 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:89,256,189...89,272,860
Ensembl chr 1:89,256,189...89,272,860 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G HMGB1 high mobility group box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HMGB2 high mobility group box 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:173,331,376...173,334,358
Ensembl chr 4:173,331,376...173,334,432 		JBrowse link
G IFI35 interferon induced protein 35 involved_in IDA
IEA		 (PMID:29038465) UniProt
Ensembl		 PMID:29038465 GO_REF:0000107 NCBI chr17:43,006,784...43,014,456
Ensembl chr17:43,006,740...43,014,456 		JBrowse link
G IFNB1 interferon beta 1 involved_in NAS (PMID:11987821) UniProt PMID:11987821 NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942 		JBrowse link
G IFNK interferon kappa involved_in TAS (PMID:11514542) UniProt PMID:11514542 NCBI chr 9:27,524,290...27,526,498
Ensembl chr 9:27,524,290...27,526,498 		JBrowse link
G KAT5 lysine acetyltransferase 5 involved_in IDA (PMID:32817552) UniProt PMID:32817552 NCBI chr11:65,712,018...65,719,604
Ensembl chr11:65,711,996...65,719,604 		JBrowse link
G LGALS9 galectin 9 involved_in ISO (PMID:20937702) UniProt PMID:20937702 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G NMI N-myc and STAT interactor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:151,270,470...151,289,668
Ensembl chr 2:151,270,470...151,289,894 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:15692051)
(PMID:21156799)		 MGI
BHF-UCL		 PMID:15692051 PMID:21156799 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PLSCR1 phospholipid scramblase 1 involved_in IMP (PMID:15308695) UniProt PMID:15308695 NCBI chr 3:146,515,180...146,544,607
Ensembl chr 3:146,515,180...146,544,856 		JBrowse link
G POLR3B RNA polymerase III subunit B involved_in IMP (PMID:19609254) UniProt PMID:19609254 NCBI chr12:106,357,748...106,510,198
Ensembl chr12:106,357,748...106,510,198 		JBrowse link
G POLR3C RNA polymerase III subunit C involved_in IMP (PMID:19609254) UniProt PMID:19609254 NCBI chr 1:145,824,200...145,844,402
Ensembl chr 1:145,824,053...145,844,402 		JBrowse link
G POLR3D RNA polymerase III subunit D involved_in IDA (PMID:19631370) UniProt PMID:19631370 NCBI chr 8:22,245,133...22,254,601
Ensembl chr 8:22,245,133...22,254,601 		JBrowse link
G POLR3F RNA polymerase III subunit F involved_in IMP (PMID:19631370) UniProt PMID:19631370 NCBI chr20:18,467,390...18,484,646
Ensembl chr20:18,466,878...18,484,648 		JBrowse link
G POLR3G RNA polymerase III subunit G involved_in IMP (PMID:19609254), (PMID:19631370) UniProt PMID:19609254 PMID:19631370 NCBI chr 5:90,473,929...90,514,557
Ensembl chr 5:90,471,748...90,514,557 		JBrowse link
G RIOK3 RIO kinase 3 involved_in IMP (PMID:24807708) UniProt PMID:24807708 NCBI chr18:23,453,287...23,483,140
Ensembl chr18:23,453,287...23,486,603 		JBrowse link
G RNF185 ring finger protein 185 involved_in IDA (PMID:28273161) UniProt PMID:28273161 NCBI chr22:31,160,182...31,207,019
Ensembl chr22:31,160,182...31,207,019 		JBrowse link
G SH2D1B SH2 domain containing 1B involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:162,395,268...162,412,136
Ensembl chr 1:162,395,268...162,412,138 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IDA (PMID:32433612) UniProt PMID:32433612 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in ISO (PMID:21531336) UniProt PMID:21531336 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IDA (PMID:32433612) UniProt PMID:32433612 NCBI chr  X:30,558,809...30,577,766
Ensembl chr  X:30,558,809...30,577,766 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in ISO (PMID:16301656) BHF-UCL PMID:16301656 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR8 toll like receptor 8 involved_in IDA (PMID:16123302) UniProt PMID:16123302 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169 		JBrowse link
G TRIM56 tripartite motif containing 56 involved_in IDA (PMID:29426904) UniProt PMID:29426904 NCBI chr 7:101,085,481...101,097,967
Ensembl chr 7:101,085,481...101,097,967 		JBrowse link
G ZDHHC4 zinc finger DHHC-type palmitoyltransferase 4 involved_in IDA (PMID:35606353) UniProt PMID:35606353 NCBI chr 7:6,577,454...6,589,374
Ensembl chr 7:6,577,434...6,589,374 		JBrowse link
positive regulation of lipopolysaccharide-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728 		JBrowse link
G CD14 CD14 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD180 CD180 molecule acts_upstream_of_or_within
involved_in		 IGI
IEA
IBA		 (PMID:10880523) MGI
Ensembl
GO_Central		 PMID:10880523 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:67,179,613...67,196,799
Ensembl chr 5:67,179,613...67,196,799 		JBrowse link
G LY86 lymphocyte antigen 86 acts_upstream_of_or_within
involved_in		 IGI
IEA
IBA		 (PMID:10880523) MGI
Ensembl
GO_Central		 PMID:10880523 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:6,588,720...6,654,982
Ensembl chr 6:6,588,108...6,654,983 		JBrowse link
G LY96 lymphocyte antigen 96 involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:73,991,392...74,099,857
Ensembl chr 8:73,991,392...74,029,079 		JBrowse link
G MIF macrophage migration inhibitory factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G PRKCA protein kinase C alpha involved_in IMP (PMID:9830023) UniProt PMID:9830023 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:112,418,947...112,509,918
Ensembl chr12:112,418,351...112,509,918 		JBrowse link
G SASH1 SAM and SH3 domain containing 1 acts_upstream_of_or_within IMP (PMID:23776175) MGI PMID:23776175 NCBI chr 6:148,193,468...148,552,044
Ensembl chr 6:148,272,304...148,552,044 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:5,208,920...5,234,860
Ensembl chr17:5,208,920...5,234,860 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
positive regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD17 ankyrin repeat domain 17 involved_in IDA (PMID:22328336) UniProt PMID:22328336 NCBI chr 4:73,073,376...73,258,798
Ensembl chr 4:73,073,376...73,258,798 		JBrowse link
G DDX60 DExD/H-box helicase 60 involved_in IMP (PMID:21791617) UniProt PMID:21791617 NCBI chr 4:168,216,294...168,325,979
Ensembl chr 4:168,216,291...168,318,883 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714 		JBrowse link
G USP17L2 ubiquitin specific peptidase 17 like family member 2 (gene/pseudogene) involved_in IMP (PMID:20368735) UniProt PMID:20368735 NCBI chr 8:12,136,435...12,138,849
Ensembl chr 8:12,136,435...12,138,849 		JBrowse link
positive regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCDC134 coiled-coil domain containing 134 involved_in IDA (PMID:38670073) UniProt PMID:38670073 NCBI chr22:41,800,679...41,832,164
Ensembl chr22:41,800,679...41,832,164 		JBrowse link
positive regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD160 CD160 molecule involved_in IDA (PMID:17307798) UniProt PMID:17307798 NCBI chr 1:145,719,499...145,739,288
Ensembl chr 1:145,719,471...145,739,288 		JBrowse link
G CD226 CD226 molecule involved_in
acts_upstream_of_or_within		 IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr18:69,853,274...69,961,773
Ensembl chr18:69,831,158...69,961,803 		JBrowse link
G CLNK cytokine dependent hematopoietic cell linker involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:10,486,395...10,734,846
Ensembl chr 4:10,486,395...10,684,768 		JBrowse link
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:15100275 RGD:2303778 NCBI chr 7:150,737,418...150,743,646
Ensembl chr 7:150,722,253...150,750,033 		JBrowse link
G HLA-E major histocompatibility complex, class I, E involved_in IDA (PMID:30134159) UniProt PMID:30134159 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194 		JBrowse link
G HLA-F major histocompatibility complex, class I, F involved_in IDA (PMID:27455421) UniProt PMID:27455421 NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528 		JBrowse link
G HLA-G major histocompatibility complex, class I, G involved_in IDA (PMID:16366734), (PMID:19304799), (PMID:23184984) UniProt PMID:16366734 PMID:19304799 PMID:23184984 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125 		JBrowse link
G IL21 interleukin 21 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066 		JBrowse link
G KIR2DL4 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 involved_in IDA (PMID:16366734), (PMID:19304799), (PMID:23184984) UniProt PMID:16366734 PMID:19304799 PMID:23184984 NCBI chr19:54,803,610...54,814,517
Ensembl chr19:54,803,610...54,814,517 		JBrowse link
G RAET1G retinoic acid early transcript 1G involved_in IDA (PMID:18544572) UniProt PMID:18544572 NCBI chr 6:149,916,878...149,923,121
Ensembl chr 6:149,916,878...149,923,121 		JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP1G1 adaptor related protein complex 1 subunit gamma 1 involved_in IMP (PMID:23632890) UniProt PMID:23632890 NCBI chr16:71,729,000...71,808,834
Ensembl chr16:71,729,000...71,809,201 		JBrowse link
G CD160 CD160 molecule involved_in IDA (PMID:19109136) UniProt PMID:19109136 NCBI chr 1:145,719,499...145,739,288
Ensembl chr 1:145,719,471...145,739,288 		JBrowse link
G HLA-F major histocompatibility complex, class I, F involved_in IDA (PMID:27455421) UniProt PMID:27455421 NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528 		JBrowse link
G KLRC2 killer cell lectin like receptor C2 involved_in IDA (PMID:21825173) UniProt PMID:21825173 NCBI chr12:10,430,599...10,436,010
Ensembl chr12:10,426,854...10,442,300 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 involved_in IMP (PMID:23632890) UniProt PMID:23632890 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672 		JBrowse link
positive regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP1G1 adaptor related protein complex 1 subunit gamma 1 involved_in IMP (PMID:23632890) UniProt PMID:23632890 NCBI chr16:71,729,000...71,808,834
Ensembl chr16:71,729,000...71,809,201 		JBrowse link
G BID BH3 interacting domain death agonist ISO RGD PMID:17893612 RGD:408346749 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G CADM1 cell adhesion molecule 1 involved_in ISS
IDA		 (PMID:12826663)
(PMID:15811952)		 UniProt PMID:12826663 PMID:15811952 NCBI chr11:115,169,236...115,504,415
Ensembl chr11:115,169,218...115,504,957 		JBrowse link
G CD160 CD160 molecule involved_in IDA (PMID:12486241), (PMID:17307798) UniProt PMID:12486241 PMID:17307798 NCBI chr 1:145,719,499...145,739,288
Ensembl chr 1:145,719,471...145,739,288 		JBrowse link
G CD226 CD226 molecule involved_in IMP (PMID:16304049) BHF-UCL PMID:16304049 NCBI chr18:69,853,274...69,961,773
Ensembl chr18:69,831,158...69,961,803 		JBrowse link
G CRTAM cytotoxic and regulatory T cell molecule involved_in IEA
IDA		 (PMID:15811952) Ensembl
HGNC-UCL		 PMID:15811952 GO_REF:0000107 NCBI chr11:122,838,500...122,872,643
Ensembl chr11:122,838,500...122,872,643 		JBrowse link
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:15100275 RGD:2303778 NCBI chr 7:150,737,418...150,743,646
Ensembl chr 7:150,722,253...150,750,033 		JBrowse link
G HLA-E major histocompatibility complex, class I, E involved_in IDA (PMID:23335510) UniProt PMID:23335510 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194 		JBrowse link
G HLA-G major histocompatibility complex, class I, G acts_upstream_of_or_within ISO (PMID:16476767) MGI PMID:16476767 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125 		JBrowse link
G IL12A interleukin 12A involved_in IDA (PMID:2204066) UniProt PMID:2204066 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019 		JBrowse link
G IL18RAP interleukin 18 receptor accessory protein acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:102,418,621...102,452,565
Ensembl chr 2:102,418,689...102,452,565 		JBrowse link
G IL21 interleukin 21 involved_in
acts_upstream_of_or_within		 IDA
IEA
IBA		 (PMID:18005035) CACAO
Ensembl
GO_Central		 PMID:18005035 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066 		JBrowse link
G KLRC1 killer cell lectin like receptor C1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:10,442,264...10,454,685
Ensembl chr12:10,442,264...10,454,685 		JBrowse link
G KLRC2 killer cell lectin like receptor C2 involved_in IDA
IBA		 (PMID:9754572) UniProt
GO_Central		 PMID:9754572 GO_REF:0000033 NCBI chr12:10,430,599...10,436,010
Ensembl chr12:10,426,854...10,442,300 		JBrowse link
G KLRC3 killer cell lectin like receptor C3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:10,412,315...10,420,595
Ensembl chr12:10,412,315...10,420,595 		JBrowse link
G KLRC4 killer cell lectin like receptor C4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:10,407,384...10,409,757
Ensembl chr12:10,403,059...10,409,757 		JBrowse link
G KLRC4-KLRK1 KLRC4-KLRK1 readthrough involved_in IDA
IBA
IEA		 (PMID:15294961) UniProt
GO_Central
InterPro
Ensembl		 PMID:15294961 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr12:10,372,353...10,410,146
Ensembl chr12:10,372,353...10,410,146
Ensembl chr12:10,372,353...10,410,146 		JBrowse link
G KLRD1 killer cell lectin like receptor D1 involved_in IDA
IBA		 (PMID:9754572) UniProt
GO_Central		 PMID:9754572 GO_REF:0000033 NCBI chr12:10,238,961...10,329,608
Ensembl chr12:10,226,058...10,329,608 		JBrowse link
G KLRF2 killer cell lectin like receptor F2 acts_upstream_of_or_within ISO (PMID:10229823), (PMID:10229828) MGI PMID:10229823 PMID:10229828 NCBI chr12:9,881,489...9,895,833
Ensembl chr12:9,881,489...9,895,833 		JBrowse link
G KLRK1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 (PMID:12645935)
(PMID:15294961)		 Ensembl
MGI
GO_Central
InterPro
UniProt		 PMID:12645935 PMID:15294961 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874 		JBrowse link
G LAG3 lymphocyte activating 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:6,772,520...6,778,455
Ensembl chr12:6,772,512...6,778,455 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 involved_in IMP (PMID:23632890) UniProt PMID:23632890 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672 		JBrowse link
G NCR3 natural cytotoxicity triggering receptor 3 involved_in IEA
IBA
IMP		 (PMID:16304049) InterPro
GO_Central
BHF-UCL		 PMID:16304049 GO_REF:0000002 GO_REF:0000033 NCBI chr 6:31,588,895...31,593,006
Ensembl chr 6:31,588,895...31,593,006 		JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IMP (PMID:16304049) BHF-UCL PMID:16304049 NCBI chr19:44,846,297...44,889,223
Ensembl chr19:44,846,175...44,889,223 		JBrowse link
G PVR PVR cell adhesion molecule involved_in IMP (PMID:16304049) BHF-UCL PMID:16304049 NCBI chr19:44,643,910...44,666,162
Ensembl chr19:44,643,798...44,666,162 		JBrowse link
G RAET1E retinoic acid early transcript 1E involved_in IDA (PMID:18544572) UniProt PMID:18544572 NCBI chr 6:149,883,179...149,898,113
Ensembl chr 6:149,883,179...149,898,113 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in IMP (PMID:19933860) UniProt PMID:19933860 NCBI chr15:38,488,103...38,564,814
Ensembl chr15:38,488,103...38,565,575 		JBrowse link
G SH2D1A SH2 domain containing 1A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:124,346,563...124,373,160
Ensembl chr  X:124,227,868...124,373,197 		JBrowse link
G SH2D1B SH2 domain containing 1B acts_upstream_of_or_within ISO (PMID:19648922)
(PMID:20962259)		 MGI PMID:19648922 PMID:20962259 NCBI chr 1:162,395,268...162,412,136
Ensembl chr 1:162,395,268...162,412,138 		JBrowse link
G SLAMF6 SLAM family member 6 involved_in IDA (PMID:16920955) UniProt PMID:16920955 NCBI chr 1:160,485,036...160,523,255
Ensembl chr 1:160,485,030...160,523,262 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:42,199,177...42,288,370
Ensembl chr17:42,199,176...42,288,633 		JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:6,772,708...6,857,361
Ensembl chr19:6,772,708...6,857,366 		JBrowse link
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD226 CD226 molecule involved_in IMP (PMID:12913096) BHF-UCL PMID:12913096 NCBI chr18:69,853,274...69,961,773
Ensembl chr18:69,831,158...69,961,803 		JBrowse link
G CRTAM cytotoxic and regulatory T cell molecule involved_in IDA
IBA
IEA		 (PMID:15811952) HGNC-UCL
GO_Central
Ensembl		 PMID:15811952 GO_REF:0000033 GO_REF:0000107 NCBI chr11:122,838,500...122,872,643
Ensembl chr11:122,838,500...122,872,643 		JBrowse link
G IL12A interleukin 12A involved_in IDA (PMID:7903063) UniProt PMID:7903063 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019 		JBrowse link
G IL12B interleukin 12B involved_in IDA (PMID:7903063) UniProt PMID:7903063 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G KLRK1 killer cell lectin like receptor K1 ISO RGD PMID:16323246 RGD:9685180 NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874 		JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IMP
IBA		 (PMID:12913096) BHF-UCL
GO_Central		 PMID:12913096 GO_REF:0000033 NCBI chr19:44,846,297...44,889,223
Ensembl chr19:44,846,175...44,889,223 		JBrowse link
G PVR PVR cell adhesion molecule involved_in IMP (PMID:12913096) BHF-UCL PMID:12913096 NCBI chr19:44,643,910...44,666,162
Ensembl chr19:44,643,798...44,666,162 		JBrowse link
positive regulation of natural killer cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD160 CD160 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:145,719,499...145,739,288
Ensembl chr 1:145,719,471...145,739,288 		JBrowse link
positive regulation of natural killer cell mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPP4 dipeptidyl peptidase 4 ISO RGD PMID:19327106 RGD:41408336 NCBI chr 2:161,992,245...162,074,215
Ensembl chr 2:161,992,245...162,074,394 		JBrowse link
G HLA-E major histocompatibility complex, class I, E involved_in IDA (PMID:9754572) UniProt PMID:9754572 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194 		JBrowse link
G RASGRP4 RAS guanyl releasing protein 4 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:38,409,058...38,426,219
Ensembl chr19:38,409,051...38,426,305 		JBrowse link
G SH2D1B SH2 domain containing 1B involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:162,395,268...162,412,136
Ensembl chr 1:162,395,268...162,412,138 		JBrowse link
positive regulation of neutrophil mediated killing of fungus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG1 arginase 1 involved_in IMP (PMID:15546957) UniProt PMID:15546957 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 involved_in ISO (PMID:10725737) UniProt PMID:10725737 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G POMC proopiomelanocortin involved_in IDA (PMID:10670585) UniProt PMID:10670585 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903 		JBrowse link
positive regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2RL1 F2R like trypsin receptor 1 involved_in IDA (PMID:21501162) UniProt PMID:21501162 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAT1 alpha tubulin acetyltransferase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:30,626,874...30,646,821
Ensembl chr 6:30,626,842...30,646,823 		JBrowse link
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISS
IDA		 (PMID:28943315) UniProt PMID:28943315 GO_REF:0000024 NCBI chr  X:155,071,508...155,123,077
Ensembl chr  X:155,071,420...155,123,077 		JBrowse link
G BTK Bruton tyrosine kinase involved_in IDA
IEA		 (PMID:34554188) UniProt
Ensembl		 PMID:34554188 GO_REF:0000107 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796 		JBrowse link
G CASP4 caspase 4 involved_in ISO (PMID:26173909) UniProt PMID:26173909 NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in ISS UniProt GO_REF:0000024 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472 		JBrowse link
G DHX33 DEAH-box helicase 33 involved_in IDA (PMID:23871209) UniProt PMID:23871209 NCBI chr17:5,440,917...5,468,982
Ensembl chr17:5,440,917...5,468,982 		JBrowse link
G GBP5 guanylate binding protein 5 involved_in IDA (PMID:22461501) UniProt PMID:22461501 NCBI chr 1:89,256,189...89,272,860
Ensembl chr 1:89,256,189...89,272,860 		JBrowse link
G KCNK6 potassium two pore domain channel subfamily K member 6 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:38,319,845...38,332,076
Ensembl chr19:38,319,845...38,332,076 		JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in IDA
IEA		 (PMID:39173637) UniProt
Ensembl		 PMID:39173637 GO_REF:0000107 NCBI chr 6:149,658,153...149,718,101
Ensembl chr 6:149,658,153...149,718,105 		JBrowse link
G LATS2 large tumor suppressor kinase 2 involved_in IDA
IEA		 (PMID:39173637) UniProt
Ensembl		 PMID:39173637 GO_REF:0000107 NCBI chr13:20,973,036...21,061,586
Ensembl chr13:20,973,036...21,061,586 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 involved_in IDA (PMID:28943315) UniProt PMID:28943315 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MARCHF5 membrane associated ring-CH-type finger 5 involved_in IDA (PMID:37575012) UniProt PMID:37575012 NCBI chr10:92,291,167...92,353,964
Ensembl chr10:92,291,167...92,353,964 		JBrowse link
G MARK4 microtubule affinity regulating kinase 4 involved_in IEA
IDA		 (PMID:28656979) Ensembl
UniProt		 PMID:28656979 GO_REF:0000107 NCBI chr19:45,251,271...45,305,284
Ensembl chr19:45,079,288...45,305,284 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IDA (PMID:23582325) UniProt PMID:23582325 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123 		JBrowse link
G MIR21 microRNA 21 ISO RGD PMID:29084974 RGD:41404715 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IMP (PMID:33718825) UniProt PMID:33718825 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G NEK7 NIMA related kinase 7 involved_in IEA
IDA
IBA		 (PMID:31189953), (PMID:36442502), (PMID:39173637) Ensembl
UniProt
GO_Central		 PMID:31189953 PMID:36442502 PMID:39173637 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:198,156,998...198,322,420
Ensembl chr 1:198,156,994...198,322,420 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032 		JBrowse link
G PLCG2 phospholipase C gamma 2 acts_upstream_of_or_within IMP (PMID:32514138) ARUK-UCL PMID:32514138 NCBI chr16:81,739,041...81,962,685
Ensembl chr16:81,738,248...81,962,685 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,193,978...134,226,073 		JBrowse link
G PRKD1 protein kinase D1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:29,576,479...29,927,847
Ensembl chr14:29,576,479...30,191,898 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IDA
IEA		 (PMID:27043286) UniProt
Ensembl		 PMID:27043286 GO_REF:0000107 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G STMP1 short transmembrane mitochondrial protein 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:135,662,514...135,676,416
Ensembl chr 7:135,662,496...135,693,418 		JBrowse link
G TLR4 toll like receptor 4 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G USP50 ubiquitin specific peptidase 50 acts_upstream_of_or_within IMP
IEA		 (PMID:28094437) MGI
Ensembl		 PMID:28094437 GO_REF:0000107 NCBI chr15:50,493,025...50,546,666
Ensembl chr15:50,494,018...50,546,708 		JBrowse link
G ZDHHC1 zinc finger DHHC-type containing 1 involved_in IDA
IEA		 (PMID:39173637) UniProt
Ensembl		 PMID:39173637 GO_REF:0000107 NCBI chr16:67,394,152...67,416,477
Ensembl chr16:67,394,152...67,416,833 		JBrowse link
G ZDHHC5 zinc finger DHHC-type palmitoyltransferase 5 involved_in IDA (PMID:38092000) UniProt PMID:38092000 NCBI chr11:57,668,114...57,701,182
Ensembl chr11:57,667,747...57,701,182 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC15A4 solute carrier family 15 member 4 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
G SLC46A2 solute carrier family 46 member 2 involved_in IMP (PMID:28539433) FlyBase PMID:28539433 NCBI chr 9:112,878,920...112,890,876
Ensembl chr 9:112,878,920...112,890,876 		JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in IMP (PMID:24790089) UniProt PMID:24790089 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B involved_in IMP (PMID:24790089) UniProt PMID:24790089 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254 		JBrowse link
G NAGK N-acetylglucosamine kinase involved_in IDA
IEA		 (PMID:36002575) UniProt
Ensembl		 PMID:36002575 GO_REF:0000107 NCBI chr 2:71,068,296...71,079,808
Ensembl chr 2:71,064,344...71,079,808 		JBrowse link
G PELI3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chr11:66,466,327...66,477,337
Ensembl chr11:66,466,327...66,477,337 		JBrowse link
G SLC15A3 solute carrier family 15 member 3 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:60,937,084...60,952,176
Ensembl chr11:60,937,060...60,952,653 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
positive regulation of pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZDHHC5 zinc finger DHHC-type palmitoyltransferase 5 involved_in IMP
IBA
IEA		 (PMID:31649195) UniProt
GO_Central
Ensembl		 PMID:31649195 GO_REF:0000033 GO_REF:0000107 NCBI chr11:57,668,114...57,701,182
Ensembl chr11:57,667,747...57,701,182 		JBrowse link
positive regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LBP lipopolysaccharide binding protein involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G RPS19 ribosomal protein S19 involved_in IDA (PMID:15750715) UniProt PMID:15750715 NCBI chr19:41,860,255...41,872,925
Ensembl chr19:41,860,255...41,872,925 		JBrowse link
positive regulation of response to biotic stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN1A cyclin dependent kinase inhibitor 1A ISO BMP4-induced cell death RGD PMID:11518517 RGD:10043821 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G MSX2 msh homeobox 2 ISO BMP4-induced cell death RGD PMID:11518517 RGD:10043821 NCBI chr 5:174,724,582...174,730,896
Ensembl chr 5:174,724,582...174,730,896 		JBrowse link
G PAX6 paired box 6 ISO glucose-induced insulinoma cell death RGD PMID:24953606 RGD:12790973 NCBI chr11:31,789,026...31,817,961
Ensembl chr11:31,784,779...31,817,961 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 ISO Interleukin-1beta-induced glucagonoma cell death RGD PMID:10580420 RGD:2311201 NCBI chr13:27,920,000...27,926,313
Ensembl chr13:27,920,000...27,926,313 		JBrowse link
G UCP2 uncoupling protein 2 ISO cyanide-induced neuronal cell death RGD PMID:19361538 RGD:7204430 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,061...73,982,843 		JBrowse link
positive regulation of response to type II interferon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPX hemopexin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:6,431,049...6,440,987
Ensembl chr11:6,431,049...6,442,617 		JBrowse link
positive regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD17 ankyrin repeat domain 17 involved_in IDA (PMID:22328336) UniProt PMID:22328336 NCBI chr 4:73,073,376...73,258,798
Ensembl chr 4:73,073,376...73,258,798 		JBrowse link
G DDX60 DExD/H-box helicase 60 involved_in IMP (PMID:21791617) UniProt PMID:21791617 NCBI chr 4:168,216,294...168,325,979
Ensembl chr 4:168,216,291...168,318,883 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714 		JBrowse link
G HDAC6 histone deacetylase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982 		JBrowse link
G OASL 2'-5'-oligoadenylate synthetase like involved_in IDA (PMID:25925578) ARUK-UCL PMID:25925578 NCBI chr12:121,017,761...121,039,246
Ensembl chr12:121,017,763...121,039,246 		JBrowse link
G PUM1 pumilio RNA binding family member 1 involved_in IDA (PMID:25340845) UniProt PMID:25340845 NCBI chr 1:30,931,506...31,065,717
Ensembl chr 1:30,931,506...31,065,991 		JBrowse link
G PUM2 pumilio RNA binding family member 2 involved_in IDA (PMID:25340845) UniProt PMID:25340845 NCBI chr 2:20,248,691...20,352,253
Ensembl chr 2:20,248,691...20,352,234 		JBrowse link
G TRIM15 tripartite motif containing 15 involved_in IMP (PMID:23077300) UniProt PMID:23077300 NCBI chr 6:30,163,546...30,172,693
Ensembl chr 6:30,163,206...30,172,693 		JBrowse link
G USP15 ubiquitin specific peptidase 15 involved_in IDA (PMID:24399297) CACAO PMID:24399297 NCBI chr12:62,260,404...62,416,389
Ensembl chr12:62,260,338...62,417,431 		JBrowse link
G USP17L2 ubiquitin specific peptidase 17 like family member 2 (gene/pseudogene) involved_in IMP (PMID:20368735) UniProt PMID:20368735 NCBI chr 8:12,136,435...12,138,849
Ensembl chr 8:12,136,435...12,138,849 		JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 involved_in IMP (PMID:21102435) UniProt PMID:21102435 NCBI chr 7:139,043,515...139,109,720
Ensembl chr 7:139,043,515...139,132,122 		JBrowse link
G ZCCHC3 zinc finger CCHC-type containing 3 involved_in IDA
IBA		 (PMID:30193849) UniProt
GO_Central		 PMID:30193849 GO_REF:0000033 NCBI chr20:297,570...300,321
Ensembl chr20:297,570...300,321 		JBrowse link
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MR1 major histocompatibility complex, class I-related involved_in IDA (PMID:31959982) UniProt PMID:31959982 NCBI chr 1:181,033,387...181,061,938
Ensembl chr 1:181,033,374...181,061,938 		JBrowse link
G SLC22A13 solute carrier family 22 member 13 involved_in IDA (PMID:19282870) UniProt PMID:19282870 NCBI chr 3:38,265,812...38,278,757
Ensembl chr 3:38,265,812...38,278,757 		JBrowse link
positive regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD24 CD24 molecule acts_upstream_of_or_within ISO (PMID:7774619) MGI PMID:7774619 NCBI chr 6:106,969,831...106,976,855
Ensembl chr 6:106,969,831...106,975,627 		JBrowse link
G FBXO38 F-box protein 38 involved_in IDA (PMID:30487606) UniProt PMID:30487606 NCBI chr 5:148,383,958...148,442,836
Ensembl chr 5:148,383,935...148,442,836 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 involved_in IDA (PMID:30282837) UniProt PMID:30282837 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HLA-DRB3 major histocompatibility complex, class II, DR beta 3 involved_in IDA (PMID:30282837) UniProt PMID:30282837
G HSPD1 heat shock protein family D (Hsp60) member 1 involved_in IDA (PMID:10663613) BHF-UCL PMID:10663613 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G KLHL22 kelch like family member 22 involved_in IDA (PMID:33109719) UniProt PMID:33109719 NCBI chr22:20,441,519...20,495,795
Ensembl chr22:20,441,519...20,495,844 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IDA (PMID:38377992) UniProt PMID:38377992 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma involved_in IDA (PMID:38377992) UniProt PMID:38377992 NCBI chr 7:76,326,799...76,358,991
Ensembl chr 7:76,326,799...76,358,991 		JBrowse link
positive regulation of toll-like receptor 13 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREML4 triggering receptor expressed on myeloid cells like 4 involved_in ISO (PMID:25848864) UniProt PMID:25848864 NCBI chr 6:41,228,349...41,238,882
Ensembl chr 6:41,228,339...41,238,882 		JBrowse link
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYBA cytochrome b-245 alpha chain involved_in IDA (PMID:22423966) UniProt PMID:22423966 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IMP (PMID:19865078) UniProt PMID:19865078 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G HMGB1 high mobility group box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IMP
IEA		 (PMID:26599367), (PMID:28471450) UniProt
Ensembl		 PMID:26599367 PMID:28471450 GO_REF:0000107 NCBI chr 8:8,783,354...8,893,630
Ensembl chr 8:8,783,354...8,893,630 		JBrowse link
G PJA2 praja ring finger ubiquitin ligase 2 involved_in IMP (PMID:28471450) UniProt PMID:28471450 NCBI chr 5:109,334,722...109,409,974
Ensembl chr 5:109,334,713...109,409,974 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IMP (PMID:19509286) BHF-UCL PMID:19509286 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR1 toll like receptor 1 involved_in IGI (PMID:22198949) ARUK-UCL PMID:22198949 NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,787,555...38,856,817 		JBrowse link
positive regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 involved_in IMP (PMID:25204797) UniProt PMID:25204797 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IMP (PMID:19865078) UniProt PMID:19865078 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G FLOT1 flotillin 1 involved_in IMP (PMID:25204797) UniProt PMID:25204797 NCBI chr 6:30,727,709...30,742,687
Ensembl chr 6:30,727,709...30,742,732 		JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:64,092,652...64,144,420
Ensembl chr 2:64,092,652...64,144,420 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IMP
IEA		 (PMID:23871208) UniProt
Ensembl		 PMID:23871208 GO_REF:0000107 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TRIM3 tripartite motif containing 3 involved_in IDA (PMID:32878999) UniProt PMID:32878999 NCBI chr11:6,448,613...6,474,459
Ensembl chr11:6,448,613...6,474,459 		JBrowse link
G WDFY1 WD repeat and FYVE domain containing 1 involved_in IMP
IBA
IEA		 (PMID:25736436) UniProt
GO_Central
Ensembl		 PMID:25736436 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:223,875,348...223,945,335
Ensembl chr 2:223,855,716...223,945,357 		JBrowse link
positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IDA (PMID:18622013) UniProt PMID:18622013 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G HMGB1 high mobility group box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G IFI35 interferon induced protein 35 involved_in IDA (PMID:29038465) UniProt PMID:29038465 NCBI chr17:43,006,784...43,014,456
Ensembl chr17:43,006,740...43,014,456 		JBrowse link
G LBP lipopolysaccharide binding protein involved_in IDA (PMID:11528597) BHF-UCL PMID:11528597 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G LTF lactotransferrin involved_in IMP (PMID:20345905) UniProt PMID:20345905 NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234 		JBrowse link
G NINJ1 ninjurin 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:93,121,496...93,134,251
Ensembl chr 9:93,121,496...93,134,251 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IDA (PMID:18511497) BHF-UCL PMID:18511497 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033 		JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:64,092,652...64,144,420
Ensembl chr 2:64,092,652...64,144,420 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA
IMP		 (PMID:23871208) Ensembl
UniProt		 PMID:23871208 GO_REF:0000107 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IDA
IMP		 (PMID:19412184)
(PMID:22685567)		 UniProt PMID:19412184 PMID:22685567 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IMP (PMID:19509286) BHF-UCL PMID:19509286 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TMED7-TICAM2 TMED7-TICAM2 readthrough involved_in IMP
IDA		 (PMID:22685567)
(PMID:19412184)		 UniProt PMID:19412184 PMID:22685567 NCBI chr 5:115,578,496...115,626,036
Ensembl chr 5:115,578,642...115,626,161 		JBrowse link
G WDFY1 WD repeat and FYVE domain containing 1 involved_in IEA
IBA
IMP		 (PMID:25736436) Ensembl
GO_Central
UniProt		 PMID:25736436 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:223,875,348...223,945,335
Ensembl chr 2:223,855,716...223,945,357 		JBrowse link
G ZNRF1 zinc and ring finger 1 involved_in IDA (PMID:28593998) UniProt PMID:28593998 NCBI chr16:74,999,024...75,110,994
Ensembl chr16:74,999,024...75,110,994 		JBrowse link
positive regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX3X DEAD-box helicase 3 X-linked involved_in IDA (PMID:30341167) UniProt PMID:30341167 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:6,865,885...6,898,239
Ensembl chr 2:6,865,557...6,898,239 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IMP
IEA		 (PMID:25238095), (PMID:32433612) UniProt
Ensembl		 PMID:25238095 PMID:32433612 GO_REF:0000107 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IMP (PMID:32433612) UniProt PMID:32433612 NCBI chr  X:30,558,809...30,577,766
Ensembl chr  X:30,558,809...30,577,766 		JBrowse link
G TREML4 triggering receptor expressed on myeloid cells like 4 involved_in IMP
IBA		 (PMID:25848864) UniProt
GO_Central		 PMID:25848864 GO_REF:0000033 NCBI chr 6:41,228,349...41,238,882
Ensembl chr 6:41,228,339...41,238,882 		JBrowse link
positive regulation of toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX3X DEAD-box helicase 3 X-linked involved_in IDA (PMID:30341167) UniProt PMID:30341167 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IMP (PMID:32433612) UniProt PMID:32433612 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IMP (PMID:32433612) UniProt PMID:32433612 NCBI chr  X:30,558,809...30,577,766
Ensembl chr  X:30,558,809...30,577,766 		JBrowse link
positive regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:6,865,885...6,898,239
Ensembl chr 2:6,865,557...6,898,239 		JBrowse link
G RTN4 reticulon 4 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:54,972,189...55,137,831
Ensembl chr 2:54,972,187...55,112,621 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA
IMP		 (PMID:25238095) Ensembl
UniProt		 PMID:25238095 GO_REF:0000107 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
G TLR9 toll like receptor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TREML4 triggering receptor expressed on myeloid cells like 4 involved_in ISO (PMID:25848864) UniProt PMID:25848864 NCBI chr 6:41,228,349...41,238,882
Ensembl chr 6:41,228,339...41,238,882 		JBrowse link
G ZDHHC3 zinc finger DHHC-type palmitoyltransferase 3 involved_in IDA (PMID:38169466) UniProt PMID:38169466 NCBI chr 3:44,915,261...44,976,174
Ensembl chr 3:44,915,257...44,976,185 		JBrowse link
positive regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GDI1 GDP dissociation inhibitor 1 involved_in IDA (PMID:35343654) UniProt PMID:35343654 NCBI chr  X:154,437,154...154,443,467
Ensembl chr  X:154,436,913...154,443,467 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 involved_in IDA (PMID:11584270) UniProt PMID:11584270 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931 		JBrowse link
G LRCH4 leucine rich repeats and calponin homology domain containing 4 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:100,574,011...100,586,129
Ensembl chr 7:100,574,011...100,586,129 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) UniProt PMID:20728433 NCBI chr10:96,593,315...96,720,514
Ensembl chr10:96,593,315...96,720,514 		JBrowse link
positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAR adenosine deaminase RNA specific involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:154,582,057...154,627,997
Ensembl chr 1:154,581,695...154,628,013 		JBrowse link
G FADD Fas associated via death domain involved_in IMP (PMID:21109225) UniProt PMID:21109225 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390 		JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in IEA
IDA		 (PMID:24882218) Ensembl
UniProt		 PMID:24882218 GO_REF:0000107 NCBI chr 1:206,470,476...206,496,889
Ensembl chr 1:206,470,476...206,496,889 		JBrowse link
G IRF3 interferon regulatory factor 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G IRF7 interferon regulatory factor 7 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983 		JBrowse link
G LSM14A LSM14A mRNA processing body assembly factor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:34,172,504...34,229,288
Ensembl chr19:34,172,504...34,229,288 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IDA (PMID:16127453), (PMID:20451243) BHF-UCL PMID:16127453 PMID:20451243 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123 		JBrowse link
G MMP12 matrix metallopeptidase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982 		JBrowse link
G NLRC5 NLR family CARD domain containing 5 involved_in IDA (PMID:20061403) UniProt PMID:20061403 NCBI chr16:56,989,557...57,083,520
Ensembl chr16:56,989,485...57,083,531 		JBrowse link
G RBM47 RNA binding motif protein 47 involved_in IMP (PMID:34160127) UniProt PMID:34160127 NCBI chr 4:40,423,280...40,630,852
Ensembl chr 4:40,423,267...40,630,875 		JBrowse link
G RNF185 ring finger protein 185 involved_in IDA (PMID:28273161) UniProt PMID:28273161 NCBI chr22:31,160,182...31,207,019
Ensembl chr22:31,160,182...31,207,019 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IDA
IEA		 (PMID:23910378) ComplexPortal
Ensembl		 PMID:23910378 GO_REF:0000107 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TRIM41 tripartite motif containing 41 involved_in IDA (PMID:29760876) UniProt PMID:29760876 NCBI chr 5:181,223,281...181,235,808
Ensembl chr 5:181,222,499...181,235,808 		JBrowse link
G TRIM56 tripartite motif containing 56 involved_in IDA
IBA		 (PMID:29426904) UniProt
GO_Central		 PMID:29426904 GO_REF:0000033 NCBI chr 7:101,085,481...101,097,967
Ensembl chr 7:101,085,481...101,097,967 		JBrowse link
G TRIM6 tripartite motif containing 6 involved_in IMP
IDA
IEA		 (PMID:24882218) UniProt
Ensembl		 PMID:24882218 GO_REF:0000107 NCBI chr11:5,596,111...5,612,952
Ensembl chr11:5,596,109...5,612,958 		JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K involved_in IMP (PMID:24882218) UniProt PMID:24882218 NCBI chr 4:39,698,136...39,782,792
Ensembl chr 4:39,698,109...39,782,792 		JBrowse link
G USP27X ubiquitin specific peptidase 27 X-linked involved_in IDA (PMID:31534008) UniProt PMID:31534008 NCBI chr  X:49,879,484...49,882,558
Ensembl chr  X:49,879,484...49,882,558 		JBrowse link
G USP29 ubiquitin specific peptidase 29 involved_in ISS UniProt GO_REF:0000024 NCBI chr19:57,119,087...57,131,926
Ensembl chr19:57,119,138...57,131,926 		JBrowse link
G WNT5A Wnt family member 5A involved_in IDA (PMID:19399181) BHF-UCL PMID:19399181 NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539 		JBrowse link
G ZBP1 Z-DNA binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:17618271) InterPro
MGI
GO_Central		 PMID:17618271 GO_REF:0000002 GO_REF:0000033 NCBI chr20:57,603,852...57,620,426
Ensembl chr20:57,603,846...57,620,576 		JBrowse link
positive regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPX hemopexin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:6,431,049...6,440,987
Ensembl chr11:6,431,049...6,442,617 		JBrowse link
G IRGM immunity related GTPase M involved_in IMP (PMID:16888103) UniProt PMID:16888103 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736 		JBrowse link
G MED1 mediator complex subunit 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:39,404,285...39,451,263
Ensembl chr17:39,404,285...39,451,272 		JBrowse link
G NLRC5 NLR family CARD domain containing 5 involved_in IMP
IDA		 (PMID:20639463)
(PMID:20061403)		 BHF-UCL
UniProt		 PMID:20061403 PMID:20639463 NCBI chr16:56,989,557...57,083,520
Ensembl chr16:56,989,485...57,083,531 		JBrowse link
G PARP9 poly(ADP-ribose) polymerase family member 9 involved_in IMP
IBA
IEA		 (PMID:27796300) UniProt
GO_Central
Ensembl		 PMID:27796300 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:122,527,924...122,564,784
Ensembl chr 3:122,527,924...122,564,577 		JBrowse link
G TXK TXK tyrosine kinase involved_in IDA (PMID:11859127) UniProt PMID:11859127 NCBI chr 4:48,066,393...48,134,250
Ensembl chr 4:48,063,158...48,134,250 		JBrowse link
positive regulation of xenophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRGM immunity related GTPase M involved_in IDA (PMID:25891078) UniProt PMID:25891078 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736 		JBrowse link
G LRSAM1 leucine rich repeat and sterile alpha motif containing 1 involved_in IMP (PMID:23245322) GO_Central PMID:23245322 NCBI chr 9:127,451,486...127,503,501
Ensembl chr 9:127,451,489...127,503,499 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:22033934) MGI PMID:22033934 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G OPTN optineurin involved_in IMP (PMID:21617041) ParkinsonsUK-UCL PMID:21617041 NCBI chr10:13,100,082...13,138,308
Ensembl chr10:13,099,449...13,138,308 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G RNF31 ring finger protein 31 involved_in IDA (PMID:28481331) UniProt PMID:28481331 NCBI chr14:24,146,875...24,160,655
Ensembl chr14:24,146,683...24,160,660 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:22033934) MGI PMID:22033934 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
protection from natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-A major histocompatibility complex, class I, A involved_in
NOT|involved_in		 IDA (PMID:18502829), (PMID:8839770) UniProt PMID:8839770 PMID:18502829 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572 		JBrowse link
G HLA-B major histocompatibility complex, class I, B involved_in IDA (PMID:18502829), (PMID:2784569), (PMID:8046333) UniProt PMID:2784569 PMID:8046333 PMID:18502829 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067 		JBrowse link
G HLA-E major histocompatibility complex, class I, E involved_in IDA (PMID:25631937), (PMID:9754572) UniProt PMID:9754572 PMID:25631937 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194 		JBrowse link
G HLA-G major histocompatibility complex, class I, G involved_in IDA (PMID:11290782) UniProt PMID:11290782 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125 		JBrowse link
G SERPINB4 serpin family B member 4 involved_in IMP (PMID:21857942) UniProt PMID:21857942 NCBI chr18:63,637,259...63,644,256
Ensembl chr18:63,637,259...63,644,256 		JBrowse link
G SERPINB9 serpin family B member 9 involved_in IMP (PMID:21795594) UniProt PMID:21795594 NCBI chr 6:2,887,270...2,903,309
Ensembl chr 6:2,887,173...2,903,309 		JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member ISO RGD PMID:8120379 RGD:2312378 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816 		JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:8120379 RGD:2312378 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739 		JBrowse link
regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EVPL envoplakin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:76,006,845...76,027,306
Ensembl chr17:76,004,502...76,027,306 		JBrowse link
G IVL involucrin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chr 1:152,908,546...152,911,886
Ensembl chr 1:152,908,546...152,911,886 		JBrowse link
G PPL periplakin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chr16:4,882,507...4,937,148
Ensembl chr16:4,882,507...4,960,741 		JBrowse link
regulation of antimicrobial humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 involved_in IDA (PMID:33082341) UniProt PMID:33082341 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528 		JBrowse link
G PPP2R3C protein phosphatase 2 regulatory subunit B''gamma acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:35,085,472...35,122,298
Ensembl chr14:35,085,467...35,122,517 		JBrowse link
regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFH complement factor H involved_in IDA (PMID:20378178), (PMID:28671664) ComplexPortal PMID:20378178 PMID:28671664 NCBI chr 1:196,652,043...196,747,504
Ensembl chr 1:196,651,754...196,752,476 		JBrowse link
regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR708 microRNA 708 involved_in IDA (PMID:31599428) ARUK-UCL PMID:31599428 NCBI chr11:79,402,022...79,402,109
Ensembl chr11:79,402,022...79,402,109 		JBrowse link
regulation of defense response to bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 involved_in IDA (PMID:18799727) UniProt PMID:18799727 NCBI chr 3:70,954,708...71,583,978
Ensembl chr 3:70,954,693...71,583,978 		JBrowse link
G SYT11 synaptotagmin 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:155,859,567...155,885,199
Ensembl chr 1:155,859,567...155,885,199 		JBrowse link
regulation of defense response to virus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOBEC3H apolipoprotein B mRNA editing enzyme catalytic subunit 3H acts_upstream_of_or_within ISO (PMID:293683) MGI PMID:293683 NCBI chr22:39,097,244...39,104,067
Ensembl chr22:39,097,224...39,104,067 		JBrowse link
G CCDC92 coiled-coil domain containing 92 involved_in IEA UniProt GO_REF:0000043 NCBI chr12:123,935,626...123,972,831
Ensembl chr12:123,918,660...123,972,831 		JBrowse link
G CD37 CD37 molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:49,335,406...49,340,606
Ensembl chr19:49,335,171...49,343,335 		JBrowse link
G ELMOD2 ELMO domain containing 2 involved_in IDA (PMID:17452337) UniProt PMID:17452337 NCBI chr 4:140,524,168...140,553,770
Ensembl chr 4:140,524,168...140,553,770 		JBrowse link
G HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 involved_in IDA (PMID:20308324) UniProt PMID:20308324 NCBI chr 4:88,457,119...88,506,163
Ensembl chr 4:88,457,119...88,506,163 		JBrowse link
G IL27 interleukin 27 involved_in IEA UniProt GO_REF:0000043 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051 		JBrowse link
G SPN sialophorin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:29,662,963...29,670,876
Ensembl chr16:29,662,979...29,670,876 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in ISS
IEA		 UniProt
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500 		JBrowse link
G TSPAN32 tetraspanin 32 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:2,302,013...2,318,204
Ensembl chr11:2,301,997...2,318,204 		JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within
involved_in		 IDA
IEA		 (PMID:28246125) MGI
Ensembl
UniProt		 PMID:28246125 GO_REF:0000043 GO_REF:0000107 NCBI chr 1:40,258,236...40,294,180
Ensembl chr 1:40,258,041...40,294,180 		JBrowse link
regulation of defense response to virus by host term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHX9 DExH-box helicase 9 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:182,839,347...182,887,982
Ensembl chr 1:182,839,347...182,887,982 		JBrowse link
G IFNA1 interferon alpha 1 involved_in ISO (PMID:24784232) CAFA PMID:24784232 NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316 		JBrowse link
G IFNG interferon gamma involved_in ISO (PMID:24784232) CAFA PMID:24784232 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IFNLR1 interferon lambda receptor 1 involved_in IDA (PMID:12469119) UniProt PMID:12469119 NCBI chr 1:24,154,168...24,187,289
Ensembl chr 1:24,154,168...24,187,959 		JBrowse link
G IL15 interleukin 15 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987 		JBrowse link
G IL1B interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G MMP12 matrix metallopeptidase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982 		JBrowse link
G RNF216 ring finger protein 216 involved_in IDA (PMID:19893624) UniProt PMID:19893624 NCBI chr 7:5,620,047...5,781,663
Ensembl chr 7:5,620,047...5,781,696 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in NAS (PMID:15142865) BHF-UCL PMID:15142865 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G USP17L2 ubiquitin specific peptidase 17 like family member 2 (gene/pseudogene) involved_in IMP (PMID:20368735) UniProt PMID:20368735 NCBI chr 8:12,136,435...12,138,849
Ensembl chr 8:12,136,435...12,138,849 		JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 ISO RGD PMID:12215647 RGD:634516 NCBI chr 7:139,043,515...139,109,720
Ensembl chr 7:139,043,515...139,132,122 		JBrowse link
regulation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:57,227,729...57,273,471
Ensembl chr 3:57,227,726...57,278,105 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:105,173,300...105,236,174
Ensembl chr12:105,173,297...105,236,203 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 involved_in TAS (PMID:21447281) UniProt PMID:21447281 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 involved_in TAS (PMID:21447281) UniProt PMID:21447281 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G CASP8 caspase 8 involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CD300A CD300a molecule involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:74,466,373...74,484,798
Ensembl chr17:74,466,399...74,484,798 		JBrowse link
G CD300C CD300c molecule involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:74,534,635...74,546,115
Ensembl chr17:74,534,362...74,546,133 		JBrowse link
G CD300E CD300e molecule involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:74,609,885...74,623,738
Ensembl chr17:74,609,878...74,623,738 		JBrowse link
G CD300H CD300H molecule (gene/pseudogene) involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:74,557,243...74,567,509
Ensembl chr17:74,560,701...74,567,343 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IDA (PMID:18411269) UniProt PMID:18411269 NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714 		JBrowse link
G DUSP10 dual specificity phosphatase 10 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:221,701,424...221,742,089
Ensembl chr 1:221,701,424...221,742,089 		JBrowse link
G ERAP1 endoplasmic reticulum aminopeptidase 1 involved_in NAS (PMID:12748171) UniProt PMID:12748171 NCBI chr 5:96,760,813...96,935,854
Ensembl chr 5:96,760,810...96,808,100 		JBrowse link
G FCGR2B Fc gamma receptor IIb involved_in TAS (PMID:26683154) ARUK-UCL PMID:26683154 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654 		JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:27,612,064...27,635,185
Ensembl chr 1:27,612,064...27,635,185 		JBrowse link
G IRF1 interferon regulatory factor 1 involved_in TAS (PMID:11846971) UniProt PMID:11846971 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719 		JBrowse link
G LRP8 LDL receptor related protein 8 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:53,242,364...53,328,070
Ensembl chr 1:53,242,364...53,328,469 		JBrowse link
G MYO1F myosin IF acts_upstream_of_or_within ISO (PMID:17023661) MGI PMID:17023661 NCBI chr19:8,520,778...8,577,442
Ensembl chr19:8,517,463...8,577,442 		JBrowse link
G N4BP1 NEDD4 binding protein 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:48,538,726...48,610,180
Ensembl chr16:48,538,726...48,620,148 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IC
IBA		 (PMID:20522204) BHF-UCL
GO_Central		 PMID:20522204 GO_REF:0000033 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G RNF135 ring finger protein 135 involved_in IMP
IBA		 (PMID:19017631) UniProt
GO_Central		 PMID:19017631 GO_REF:0000033 NCBI chr17:30,958,921...30,999,911
Ensembl chr17:30,970,984...30,999,911 		JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in IMP
IBA
IDA		 (PMID:19525956)
(PMID:29670289)		 UniProt
GO_Central		 PMID:19525956 PMID:29670289 GO_REF:0000033 NCBI chr20:36,889,773...36,951,708
Ensembl chr20:36,890,229...36,951,893 		JBrowse link
G SERPINB1 serpin family B member 1 involved_in ISO (PMID:17664292) UniProt PMID:17664292 NCBI chr 6:2,832,332...2,841,863
Ensembl chr 6:2,832,332...2,841,959 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IC (PMID:19509286) BHF-UCL PMID:19509286 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TKFC triokinase and FMN cyclase involved_in IDA (PMID:16289032) UniProt PMID:16289032 NCBI chr11:61,333,228...61,353,426
Ensembl chr11:61,333,220...61,353,295 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISS
IEA
IBA		 ARUK-UCL
Ensembl
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
G TREX1 three prime repair exonuclease 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in TAS (PMID:21447281) UniProt PMID:21447281 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
regulation of lipopolysaccharide-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD36 CD36 molecule (CD36 blood group) involved_in TAS (PMID:29111364) ARUK-UCL PMID:29111364 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CD55 CD55 molecule (Cromer blood group) involved_in IDA (PMID:12731067) UniProt PMID:12731067 NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804 		JBrowse link
G CD84 CD84 molecule involved_in ISO (PMID:20628063) UniProt PMID:20628063 NCBI chr 1:160,541,098...160,579,496
Ensembl chr 1:160,541,095...160,579,516 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 involved_in IDA (PMID:10652441) ARUK-UCL PMID:10652441 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G TRIM5 tripartite motif containing 5 involved_in IMP (PMID:21512573) UniProt PMID:21512573 NCBI chr11:5,588,635...5,685,074
Ensembl chr11:5,663,195...5,938,619 		JBrowse link
G TUT4 terminal uridylyl transferase 4 acts_upstream_of_or_within ISO (PMID:16643855) MGI PMID:16643855 NCBI chr 1:52,423,275...52,553,463
Ensembl chr 1:52,408,282...52,553,487 		JBrowse link
regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRF1 interferon regulatory factor 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719 		JBrowse link
G IRF7 interferon regulatory factor 7 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983 		JBrowse link
regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRF7 interferon regulatory factor 7 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983 		JBrowse link
regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALHM6 calcium homeostasis modulator family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:116,461,375...116,463,771
Ensembl chr 6:116,461,370...116,463,771 		JBrowse link
regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KLRB1 killer cell lectin like receptor B1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:9,594,551...9,607,916
Ensembl chr12:9,594,551...9,607,916 		JBrowse link
G LEP leptin involved_in IDA (PMID:12504075) UniProt PMID:12504075 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G NCR1 natural cytotoxicity triggering receptor 1 involved_in TAS (PMID:15654827) UniProt PMID:15654827 NCBI chr19:54,898,198...54,938,208
Ensembl chr19:54,906,148...54,916,140 		JBrowse link
G PIK3R6 phosphoinositide-3-kinase regulatory subunit 6 involved_in IDA
IBA		 (PMID:11062502) CACAO
GO_Central		 PMID:11062502 GO_REF:0000033 NCBI chr17:8,802,722...8,867,677
Ensembl chr17:8,802,722...8,867,677 		JBrowse link
regulation of natural killer cell mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-E major histocompatibility complex, class I, E involved_in IDA (PMID:18448674) UniProt PMID:18448674 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194 		JBrowse link
regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL6 C-X-C motif chemokine ligand 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522 		JBrowse link
G KCNK13 potassium two pore domain channel subfamily K member 13 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:90,061,994...90,185,853
Ensembl chr14:90,061,994...90,185,853 		JBrowse link
regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC2 baculoviral IAP repeat containing 2 involved_in TAS (PMID:20888210) UniProt PMID:20888210 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 involved_in TAS (PMID:20888210) UniProt PMID:20888210 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G SLC15A2 solute carrier family 15 member 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:121,894,401...121,944,188
Ensembl chr 3:121,894,401...121,944,188 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in TAS (PMID:20888210) UniProt PMID:20888210 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PELI3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chr11:66,466,327...66,477,337
Ensembl chr11:66,466,327...66,477,337 		JBrowse link
regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NCF1 neutrophil cytosolic factor 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:21275845 GO_REF:0000107 RGD:41404729 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315 		JBrowse link
G S100A9 S100 calcium binding protein A9 involved_in NAS (PMID:23123827) ComplexPortal PMID:23123827 NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023 		JBrowse link
regulation of response to DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in IMP (PMID:25928429) UniProt PMID:25928429 NCBI chr12:4,321,213...4,360,028
Ensembl chr12:4,307,763...4,360,028 		JBrowse link
regulation of response to DNA integrity checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RBM14 RNA binding motif protein 14 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:66,616,630...66,629,934
Ensembl chr11:66,616,626...66,629,934 		JBrowse link
G RBM14-RBM4 RBM14-RBM4 readthrough acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:66,616,630...66,646,468
Ensembl chr11:66,616,626...66,646,469 		JBrowse link
regulation of response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAPK1 death associated protein kinase 1 involved_in IDA (PMID:11573098) ComplexPortal PMID:11573098 NCBI chr 9:87,497,228...87,708,634
Ensembl chr 9:87,497,228...87,708,634 		JBrowse link
regulation of response to type II interferon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARP9 poly(ADP-ribose) polymerase family member 9 involved_in IDA (PMID:16809771) UniProt PMID:16809771 NCBI chr 3:122,527,924...122,564,784
Ensembl chr 3:122,527,924...122,564,577 		JBrowse link
regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC2 baculoviral IAP repeat containing 2 involved_in TAS (PMID:20888210) UniProt PMID:20888210 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 involved_in TAS (PMID:20888210) UniProt PMID:20888210 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IMP (PMID:27824081) UniProt PMID:27824081 NCBI chr19:47,745,546...47,757,058
Ensembl chr19:47,745,546...47,757,058 		JBrowse link
regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLOT2 flotillin 2 NOT|involved_in IMP (PMID:25204797) UniProt PMID:25204797 NCBI chr17:28,879,339...28,897,733
Ensembl chr17:28,879,335...28,897,733 		JBrowse link
G HCFC2 host cell factor C2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:104,064,531...104,106,524
Ensembl chr12:104,064,531...104,106,524 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IDA (PMID:37158982) UniProt PMID:37158982 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:57,227,729...57,273,471
Ensembl chr 3:57,227,726...57,278,105 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:105,173,300...105,236,174
Ensembl chr12:105,173,297...105,236,203 		JBrowse link
G FLOT1 flotillin 1 NOT|involved_in IMP (PMID:25204797) UniProt PMID:25204797 NCBI chr 6:30,727,709...30,742,687
Ensembl chr 6:30,727,709...30,742,732 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IDA (PMID:19289601) UniProt PMID:19289601 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
regulation of toll-like receptor 6 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCRL3 Fc receptor like 3 involved_in IDA (PMID:23857366) UniProt PMID:23857366 NCBI chr 1:157,676,481...157,700,956
Ensembl chr 1:157,674,321...157,700,769 		JBrowse link
regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein involved_in IGI (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 involved_in TAS (PMID:20888210) UniProt PMID:20888210 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 involved_in TAS (PMID:20888210) UniProt PMID:20888210 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IGI (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G ESR1 estrogen receptor 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor involved_in IDA (PMID:20547752) UniProt PMID:20547752 NCBI chr 1:92,473,043...92,486,925
Ensembl chr 1:92,473,043...92,486,925 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-9860276 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:8,783,354...8,893,630
Ensembl chr 8:8,783,354...8,893,630 		JBrowse link
G MIR146A microRNA 146a involved_in IDA (PMID:16885212) ARUK-UCL PMID:16885212 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450 		JBrowse link
G S100A8 S100 calcium binding protein A8 involved_in NAS (PMID:22489132), (PMID:25597447) ComplexPortal PMID:22489132 PMID:25597447 NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073 		JBrowse link
G S100A9 S100 calcium binding protein A9 involved_in NAS (PMID:23123827), (PMID:25597447) ComplexPortal PMID:23123827 PMID:25597447 NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:30,558,809...30,577,766
Ensembl chr  X:30,558,809...30,577,766 		JBrowse link
regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC37 cell division cycle 37, HSP90 cochaperone acts_upstream_of_or_within IMP (PMID:16280321) MGI PMID:16280321 NCBI chr19:10,391,133...10,403,542
Ensembl chr19:10,391,090...10,420,121 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in TAS Reactome Reactome:R-HSA-912694 NCBI chr20:50,510,383...50,585,241
Ensembl chr20:50,510,321...50,585,241 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 involved_in TAS Reactome Reactome:R-HSA-912694 NCBI chr12:112,418,947...112,509,918
Ensembl chr12:112,418,351...112,509,918 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 involved_in TAS Reactome Reactome:R-HSA-912694 NCBI chr12:6,946,577...6,961,316
Ensembl chr12:6,946,468...6,961,316 		JBrowse link
regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC37 cell division cycle 37, HSP90 cochaperone acts_upstream_of_or_within IMP (PMID:16280321) MGI PMID:16280321 NCBI chr19:10,391,133...10,403,542
Ensembl chr19:10,391,090...10,420,121 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in TAS Reactome Reactome:R-HSA-877312 NCBI chr18:12,785,478...12,884,237
Ensembl chr18:12,785,478...12,929,643 		JBrowse link
RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLPB ClpB family mitochondrial disaggregase involved_in IDA (PMID:31522117) UniProt PMID:31522117 NCBI chr11:72,285,495...72,434,531
Ensembl chr11:72,285,495...72,434,680 		JBrowse link
G LSM14A LSM14A mRNA processing body assembly factor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:34,172,504...34,229,288
Ensembl chr19:34,172,504...34,229,288 		JBrowse link
G MAVS mitochondrial antiviral signaling protein acts_upstream_of_or_within ISO (PMID:22745163) MGI PMID:22745163 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123 		JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 involved_in IMP (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chr12:112,938,474...112,973,251
Ensembl chr12:112,938,051...112,976,460 		JBrowse link
G PHB1 prohibitin 1 involved_in IDA (PMID:31522117) UniProt PMID:31522117 NCBI chr17:49,404,052...49,414,882
Ensembl chr17:49,404,049...49,414,905 		JBrowse link
G PHB2 prohibitin 2 involved_in IDA (PMID:31522117) UniProt PMID:31522117 NCBI chr12:6,965,327...6,970,753
Ensembl chr12:6,965,327...6,970,780 		JBrowse link
G RIGI RNA sensor RIG-I involved_in IDA
IMP		 (PMID:28469175)
(PMID:19211564)		 UniProt PMID:19211564 PMID:28469175 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,348 		JBrowse link
G RNF135 ring finger protein 135 involved_in IMP
IDA		 (PMID:28469175), (PMID:31006531)
(PMID:23950712)		 UniProt PMID:23950712 PMID:28469175 PMID:31006531 NCBI chr17:30,958,921...30,999,911
Ensembl chr17:30,970,984...30,999,911 		JBrowse link
G TRIM25 tripartite motif containing 25 NOT|involved_in IMP (PMID:31006531) UniProt PMID:31006531 NCBI chr17:56,887,909...56,914,049
Ensembl chr17:56,836,387...56,914,080 		JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC6A C-type lectin domain containing 6A involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:8,455,962...8,478,330
Ensembl chr12:8,455,962...8,478,330 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
G CREBBP CREB binding protein involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713 		JBrowse link
G EP300 E1A binding protein p300 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G KLRC1 killer cell lectin like receptor C1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:10,442,264...10,454,685
Ensembl chr12:10,442,264...10,454,685 		JBrowse link
G KLRC2 killer cell lectin like receptor C2 involved_in IDA
IBA		 (PMID:9655483) UniProt
GO_Central		 PMID:9655483 GO_REF:0000033 NCBI chr12:10,430,599...10,436,010
Ensembl chr12:10,426,854...10,442,300 		JBrowse link
G KLRC3 killer cell lectin like receptor C3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:10,412,315...10,420,595
Ensembl chr12:10,412,315...10,420,595 		JBrowse link
G KLRC4 killer cell lectin like receptor C4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:10,407,384...10,409,757
Ensembl chr12:10,403,059...10,409,757 		JBrowse link
G KLRC4-KLRK1 KLRC4-KLRK1 readthrough acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:10,372,353...10,410,146
Ensembl chr12:10,372,353...10,410,146
Ensembl chr12:10,372,353...10,410,146 		JBrowse link
G KLRD1 killer cell lectin like receptor D1 involved_in IDA
IBA		 (PMID:9655483) UniProt
GO_Central		 PMID:9655483 GO_REF:0000033 NCBI chr12:10,238,961...10,329,608
Ensembl chr12:10,226,058...10,329,608 		JBrowse link
G KLRK1 killer cell lectin like receptor K1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr11:77,322,017...77,530,009
Ensembl chr11:77,322,017...77,474,635 		JBrowse link
G PAK2 p21 (RAC1) activated kinase 2 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr 3:196,739,857...196,832,647
Ensembl chr 3:196,739,857...196,832,647 		JBrowse link
G PAK3 p21 (RAC1) activated kinase 3 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr  X:110,944,397...111,227,361
Ensembl chr  X:110,944,285...111,227,361 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in ISS
TAS
IEA		 ARUK-UCL
Reactome
Ensembl		 GO_REF:0000024 GO_REF:0000107 Reactome:R-HSA-5621481 NCBI chr16:81,739,041...81,962,685
Ensembl chr16:81,738,248...81,962,685 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in ISS
IEA
TAS		 ARUK-UCL
Ensembl
Reactome		 GO_REF:0000024 GO_REF:0000107 Reactome:R-HSA-5621481 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in IDA (PMID:9655483) UniProt PMID:9655483 NCBI chr19:35,904,403...35,908,295
Ensembl chr19:35,904,401...35,908,295 		JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIR2DS2 killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 involved_in IDA (PMID:9655483) UniProt PMID:9655483
G LOC124900573 killer cell immunoglobulin-like receptor 2DS2 involved_in IDA (PMID:9655483) UniProt PMID:9655483
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in IDA (PMID:9655483) UniProt PMID:9655483 NCBI chr19:35,904,403...35,908,295
Ensembl chr19:35,904,401...35,908,295 		JBrowse link
susceptibility to natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CADM1 cell adhesion molecule 1 involved_in IDA
IBA
ISS		 (PMID:15811952)
(PMID:12826663)		 UniProt
GO_Central		 PMID:12826663 PMID:15811952 GO_REF:0000033 NCBI chr11:115,169,236...115,504,415
Ensembl chr11:115,169,218...115,504,957 		JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IMP (PMID:12913096) BHF-UCL PMID:12913096 NCBI chr19:44,846,297...44,889,223
Ensembl chr19:44,846,175...44,889,223 		JBrowse link
G PVR PVR cell adhesion molecule involved_in IMP (PMID:12913096) BHF-UCL PMID:12913096 NCBI chr19:44,643,910...44,666,162
Ensembl chr19:44,643,798...44,666,162 		JBrowse link
G ULBP1 UL16 binding protein 1 acts_upstream_of_or_within ISO (PMID:12645935) MGI PMID:12645935 NCBI chr 6:149,963,943...149,973,715
Ensembl chr 6:149,963,943...149,973,715 		JBrowse link
TIRAP-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIRAP TIR domain containing adaptor protein involved_in IDA (PMID:11544529) BHF-UCL PMID:11544529 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
tolerance induction to lipopolysaccharide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in IDA (PMID:23609450) UniProt PMID:23609450 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in IMP (PMID:21220427) BHF-UCL PMID:21220427 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in
acts_upstream_of_or_within		 IMP
IBA
ISO		 (PMID:10383454)
(PMID:10549626)		 BHF-UCL
GO_Central
MGI		 PMID:10383454 PMID:10549626 GO_REF:0000033 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G LGALS9 galectin 9 NOT|involved_in IDA (PMID:16116184) UniProt PMID:16116184 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of ISO (PMID:15220916) MGI PMID:15220916 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:96,593,315...96,720,514
Ensembl chr10:96,593,315...96,720,514 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within IDA (PMID:11894098) MGI PMID:11894098 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G TLR2 toll like receptor 2 involved_in IDA (PMID:17128265) BHF-UCL PMID:17128265 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in ISS
IEA
IBA		 UniProt
Ensembl
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:2,741,648...2,756,336
Ensembl chr 4:2,741,648...2,756,342 		JBrowse link
toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule involved_in ISO (PMID:25158758) UniProt PMID:25158758 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G COLEC12 collectin subfamily member 12 involved_in IMP (PMID:25204797) UniProt PMID:25204797 NCBI chr18:316,737...500,701
Ensembl chr18:316,737...500,722 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-168164 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G LGALS9 galectin 9 involved_in ISO PMID:25158758 UniProt PMID:25158758 RGD:10054077 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in TAS Reactome Reactome:R-HSA-168164 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IMP (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chr12:112,906,962...112,933,219
Ensembl chr12:112,905,856...112,933,219 		JBrowse link
G RFTN1 raftlin, lipid raft linker 1 acts_upstream_of_or_within IMP (PMID:21266579) MGI PMID:21266579 NCBI chr 3:16,315,845...16,513,699
Ensembl chr 3:16,313,574...16,514,026 		JBrowse link
G RNF170 ring finger protein 170 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:42,849,637...42,897,299
Ensembl chr 8:42,849,637...42,897,290 		JBrowse link
G SCARA3 scavenger receptor class A member 3 NOT|involved_in IMP (PMID:25204797) UniProt PMID:25204797 NCBI chr 8:27,633,463...27,734,141
Ensembl chr 8:27,633,868...27,676,776 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:5,208,920...5,234,860
Ensembl chr17:5,208,920...5,234,860 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IDA (PMID:12471095) UniProt PMID:12471095 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712 		JBrowse link
G TLR3 toll like receptor 3 involved_in IDA (PMID:17128265), (PMID:18172197) UniProt PMID:17128265 PMID:18172197 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073 		JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in ISS
IEA
IBA		 UniProt
Ensembl
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:2,741,648...2,756,336
Ensembl chr 4:2,741,648...2,756,342 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in TAS Reactome Reactome:R-HSA-168164 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in IMP
IBA
IEA		 (PMID:18082565) UniProt
GO_Central
Ensembl		 PMID:18082565 GO_REF:0000033 GO_REF:0000107 NCBI chr11:67,991,100...68,004,097
Ensembl chr11:67,991,100...68,004,982 		JBrowse link
toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in IDA
IBA		 (PMID:27986454) UniProt
GO_Central		 PMID:27986454 GO_REF:0000033 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex involved_in IDA (PMID:26189595) UniProt PMID:26189595 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G ECSIT ECSIT signaling integrator involved_in IDA (PMID:25371197) UniProt PMID:25371197 NCBI chr19:11,505,929...11,529,134
Ensembl chr19:11,505,929...11,529,172 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:10549626) MGI
GO_Central		 PMID:10549626 GO_REF:0000033 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 involved_in IDA (PMID:17878161) UniProt PMID:17878161 NCBI chr 3:10,164,919...10,243,745
Ensembl chr 3:10,164,919...10,243,745 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 involved_in IC (PMID:35977521) UniProt PMID:35977521 NCBI chr12:43,758,951...43,789,541
Ensembl chr12:43,758,944...43,798,307 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IDA (PMID:25636800) UniProt PMID:25636800 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G LETMD1 LETM1 domain containing 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:51,048,220...51,068,958
Ensembl chr12:51,047,962...51,060,424 		JBrowse link
G LGALS9 galectin 9 NOT|involved_in IDA (PMID:16116184) UniProt PMID:16116184 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G LY96 lymphocyte antigen 96 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:73,991,392...74,099,857
Ensembl chr 8:73,991,392...74,029,079 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in IDA (PMID:25371197) UniProt PMID:25371197 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IDA
IBA		 (PMID:16751103) UniProt
GO_Central		 PMID:16751103 GO_REF:0000033 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:42,536,241...42,544,449
Ensembl chr17:42,536,241...42,544,449 		JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in
acts_upstream_of_or_within		 IDA
IEA		 (PMID:7479976) UniProt
Ensembl		 PMID:7479976 GO_REF:0000107 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NMI N-myc and STAT interactor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:151,270,470...151,289,668
Ensembl chr 2:151,270,470...151,289,894 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IMP (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chr12:112,906,962...112,933,219
Ensembl chr12:112,905,856...112,933,219 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:96,593,315...96,720,514
Ensembl chr10:96,593,315...96,720,514 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IDA (PMID:25355951) UniProt PMID:25355951 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G S100A14 S100 calcium binding protein A14 involved_in IDA
IBA		 (PMID:17625598) UniProt
GO_Central		 PMID:17625598 GO_REF:0000033 NCBI chr 1:153,614,255...153,616,325
Ensembl chr 1:153,614,255...153,616,986 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:5,208,920...5,234,860
Ensembl chr17:5,208,920...5,234,860 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IDA (PMID:28747347) UniProt PMID:28747347 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IDA (PMID:12471095) UniProt PMID:12471095 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IDA (PMID:28630139) UniProt PMID:28630139 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IDA
IBA		 (PMID:16751103) UniProt
GO_Central		 PMID:16751103 GO_REF:0000033 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 (PMID:25549946)
(PMID:10196138), (PMID:15618008), (PMID:18222170)		 Ensembl
MGI
GO_Central
UniProt		 PMID:10196138 PMID:15618008 PMID:18222170 PMID:25549946 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TMED7-TICAM2 TMED7-TICAM2 readthrough involved_in IDA (PMID:28630139) UniProt PMID:28630139 NCBI chr 5:115,578,496...115,626,036
Ensembl chr 5:115,578,642...115,626,161 		JBrowse link
G TMEM126A transmembrane protein 126A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:85,647,967...85,656,542
Ensembl chr11:85,647,967...85,656,547 		JBrowse link
G TNIP3 TNFAIP3 interacting protein 3 involved_in IDA (PMID:17088249) UniProt PMID:17088249 NCBI chr 4:121,131,408...121,227,483
Ensembl chr 4:121,131,408...121,227,466 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IDA (PMID:18222170) UniProt PMID:18222170 NCBI chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IDA (PMID:25371197) UniProt PMID:25371197 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TRIL TLR4 interactor with leucine rich repeats involved_in IDA
IBA		 (PMID:19710467) UniProt
GO_Central		 PMID:19710467 GO_REF:0000033 NCBI chr 7:28,953,358...28,958,330
Ensembl chr 7:28,953,358...28,958,330 		JBrowse link
toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IDA (PMID:16751103) UniProt PMID:16751103 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G TIRAP TIR domain containing adaptor protein NOT|involved_in ISO (PMID:12447442) BHF-UCL PMID:12447442 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR5 toll like receptor 5 involved_in IDA (PMID:14625549), (PMID:17128265) BHF-UCL PMID:14625549 PMID:17128265 NCBI chr 1:223,109,404...223,143,248
Ensembl chr 1:223,109,404...223,143,292 		JBrowse link
toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:96,593,315...96,720,514
Ensembl chr10:96,593,315...96,720,514 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:5,208,920...5,234,860
Ensembl chr17:5,208,920...5,234,860 		JBrowse link
G TLR7 toll like receptor 7 involved_in IEA
IBA
IDA		 (PMID:12032557) Ensembl
GO_Central		 PMID:12032557 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in IMP
IBA
IEA		 (PMID:19006693) UniProt
GO_Central
Ensembl		 PMID:19006693 GO_REF:0000033 GO_REF:0000107 NCBI chr11:67,991,100...68,004,097
Ensembl chr11:67,991,100...68,004,982 		JBrowse link
toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IDA (PMID:33718825) UniProt PMID:33718825 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G TLR7 toll like receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
G TLR8 toll like receptor 8 involved_in IDA (PMID:12032557), (PMID:24942581), (PMID:33718825) UniProt PMID:12032557 PMID:24942581 PMID:33718825 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169 		JBrowse link
toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPG5 ectopic P-granules 5 autophagy tethering factor acts_upstream_of_positive_effect IMP (PMID:29130391) UniProt PMID:29130391 NCBI chr18:45,800,581...45,967,329
Ensembl chr18:45,800,581...45,967,329 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in TAS Reactome Reactome:R-HSA-168138 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 involved_in TAS Reactome Reactome:R-HSA-168138 NCBI chr12:43,758,951...43,789,541
Ensembl chr12:43,758,944...43,798,307 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:96,593,315...96,720,514
Ensembl chr10:96,593,315...96,720,514 		JBrowse link
G TLR9 toll like receptor 9 involved_in IDA (PMID:23857366) UniProt PMID:23857366 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:2,741,648...2,756,336
Ensembl chr 4:2,741,648...2,756,342 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in IMP
ISS
IBA
IEA		 (PMID:19006693) UniProt
GO_Central
Ensembl		 PMID:19006693 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr11:67,991,100...68,004,097
Ensembl chr11:67,991,100...68,004,982 		JBrowse link
toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP3B1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:78,000,522...78,294,698
Ensembl chr 5:77,991,640...78,294,762 		JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IDA (PMID:16831874) UniProt PMID:16831874 NCBI chr 1:85,265,776...85,276,632
Ensembl chr 1:85,265,776...85,276,632 		JBrowse link
G CD86 CD86 molecule acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CTSS cathepsin S involved_in TAS Reactome Reactome:R-HSA-168898 NCBI chr 1:150,730,188...150,765,778
Ensembl chr 1:150,730,079...150,765,957 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in TAS Reactome Reactome:R-HSA-168181 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 ISO RGD PMID:27832756 RGD:34888235 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 involved_in TAS (PMID:21269878) Reactome PMID:21269878 Reactome:R-HSA-168181 NCBI chr12:43,758,951...43,789,541
Ensembl chr12:43,758,944...43,798,307 		JBrowse link
G LRRC19 leucine rich repeat containing 19 involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:26,993,136...27,005,672
Ensembl chr 9:26,993,136...27,005,672 		JBrowse link
G LY96 lymphocyte antigen 96 involved_in IDA (PMID:14607928) ComplexPortal PMID:14607928 NCBI chr 8:73,991,392...74,099,857
Ensembl chr 8:73,991,392...74,029,079 		JBrowse link
G MAPKAPK2 MAPK activated protein kinase 2 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:206,684,905...206,734,281
Ensembl chr 1:206,684,905...206,734,281 		JBrowse link
G MAPKAPK3 MAPK activated protein kinase 3 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:50,611,520...50,649,291
Ensembl chr 3:50,611,520...50,649,291 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:81,739,041...81,962,685
Ensembl chr16:81,738,248...81,962,685 		JBrowse link
G RPS6KA3 ribosomal protein S6 kinase A3 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:20,149,911...20,267,097
Ensembl chr  X:20,149,911...20,267,519 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IDA (PMID:12471095) UniProt PMID:12471095 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712 		JBrowse link
G TIFAB TIFA inhibitor acts_upstream_of_negative_effect IEA Ensembl GO_REF:0000107 NCBI chr 5:135,444,226...135,452,351
Ensembl chr 5:135,444,226...135,452,351 		JBrowse link
G TLR1 toll like receptor 1 involved_in ISO
IBA
IEA
ISS
IDA		 (PMID:16893894) RGD
GO_Central
Ensembl
ComplexPortal
InterPro		 PMID:16893894 PMID:16973131 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000114 RGD:1643119 NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,787,555...38,856,817 		JBrowse link
G TLR10 toll like receptor 10 involved_in IEA
IBA
ISS		 InterPro
GO_Central
ComplexPortal		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000114 NCBI chr 4:38,772,238...38,782,990
Ensembl chr 4:38,772,238...38,782,990 		JBrowse link
G TLR2 toll like receptor 2 involved_in ISO
IBA
IEA
ISS
IDA		 (PMID:16893894) RGD
GO_Central
UniProt
ComplexPortal
InterPro		 PMID:16893894 PMID:16973131 PMID:18353287 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000114 RGD:1643119 RGD:5684896 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR3 toll like receptor 3 involved_in ISO
IEA
IDA		 (PMID:18172197) RGD
Ensembl
UniProt
InterPro		 PMID:16973131 PMID:18172197 GO_REF:0000002 GO_REF:0000107 RGD:1643119 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073 		JBrowse link
G TLR4 toll like receptor 4 involved_in ISO
IDA
IEA		 (PMID:14607928) RGD
ComplexPortal
InterPro		 PMID:14607928 PMID:16973131 GO_REF:0000002 RGD:1643119 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR5 toll like receptor 5 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:223,109,404...223,143,248
Ensembl chr 1:223,109,404...223,143,292 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISO
IEA
IBA		 RGD
Ensembl
GO_Central
InterPro		 PMID:16973131 PMID:18353287 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:1643119 RGD:5684896 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G TLR7 toll like receptor 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
G TLR8 toll like receptor 8 involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169 		JBrowse link
G TLR9 toll like receptor 9 involved_in ISO
IEA
IBA
IDA		 (PMID:17128265) RGD
Ensembl
GO_Central
BHF-UCL		 PMID:16973131 PMID:17128265 GO_REF:0000033 GO_REF:0000107 RGD:1643119 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IEA
IDA
ISS		 (PMID:18222170) Ensembl
UniProt		 PMID:18222170 GO_REF:0000024 GO_REF:0000107 NCBI chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in
acts_upstream_of_or_within		 IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr11:67,991,100...68,004,097
Ensembl chr11:67,991,100...68,004,982 		JBrowse link
toll-like receptor TLR1:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:5,208,920...5,234,860
Ensembl chr17:5,208,920...5,234,860 		JBrowse link
toll-like receptor TLR6:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IDA (PMID:36964784) UniProt PMID:36964784 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IDA (PMID:27708357) UniProt PMID:27708357 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G TLR2 toll like receptor 2 involved_in IDA (PMID:23626692) ComplexPortal PMID:23626692 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR6 toll like receptor 6 involved_in IDA (PMID:23626692) ComplexPortal PMID:23626692 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
TRAM-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCE protein kinase C epsilon involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990 		JBrowse link
G RAB11FIP2 RAB11 family interacting protein 2 involved_in IDA (PMID:30883606) UniProt PMID:30883606 NCBI chr10:118,004,916...118,046,941
Ensembl chr10:118,004,916...118,046,941 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IDA
IMP		 (PMID:19412184)
(PMID:22685567)		 UniProt PMID:19412184 PMID:22685567 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TMED7-TICAM2 TMED7-TICAM2 readthrough involved_in IMP
IDA		 (PMID:22685567)
(PMID:19412184)		 UniProt PMID:19412184 PMID:22685567 NCBI chr 5:115,578,496...115,626,036
Ensembl chr 5:115,578,642...115,626,161 		JBrowse link
TRIF-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD274 CD274 molecule involved_in IDA (PMID:36232715) UniProt PMID:36232715 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G CD300LF CD300 molecule like family member f involved_in IMP (PMID:22043923) UniProt PMID:22043923 NCBI chr17:74,694,317...74,712,923
Ensembl chr17:74,694,311...74,712,978 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-937061 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IDA (PMID:25636800) UniProt PMID:25636800 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in TAS Reactome Reactome:R-HSA-937061 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in ISS
IBA
IEA
IMP		 (PMID:25636800) ParkinsonsUK-UCL
GO_Central
InterPro
CACAO
Ensembl		 PMID:25636800 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TLR4 toll like receptor 4 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G TMED7-TICAM2 TMED7-TICAM2 readthrough involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:115,578,496...115,626,036
Ensembl chr 5:115,578,642...115,626,161 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in TAS Reactome Reactome:R-HSA-9013973 Reactome:R-HSA-936964 NCBI chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in TAS Reactome Reactome:R-HSA-937061 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 27142
    response to stimulus 16528
      response to biotic stimulus 2092
        regulation of response to biotic stimulus 643
          negative regulation of response to biotic stimulus + 146
          positive regulation of response to biotic stimulus + 474
          regulation of antimicrobial humoral response + 15
          regulation of defense response to bacterium + 25
          regulation of defense response to fungus + 8
          regulation of defense response to insect + 0
          regulation of defense response to oomycetes + 0
          regulation of defense response to virus + 74
          regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus + 0
          regulation of innate immune response + 525
          regulation of lipopolysaccharide-mediated signaling pathway + 33
          regulation of neutrophil mediated killing of symbiont cell + 5
          regulation of response to cell cycle checkpoint signaling + 3
          regulation of response to tumor cell + 36
          regulation of systemic acquired resistance + 0
          regulation of xenophagy + 10
Path 2
Term Annotations click to browse term
  biological_process 27142
    biological regulation 13699
      regulation of biological process 13240
        regulation of response to stimulus 4654
          regulation of response to biotic stimulus 643
            negative regulation of response to biotic stimulus + 146
            positive regulation of response to biotic stimulus + 474
            regulation of antimicrobial humoral response + 15
            regulation of defense response to bacterium + 25
            regulation of defense response to fungus + 8
            regulation of defense response to insect + 0
            regulation of defense response to oomycetes + 0
            regulation of defense response to virus + 74
            regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus + 0
            regulation of innate immune response + 525
            regulation of lipopolysaccharide-mediated signaling pathway + 33
            regulation of neutrophil mediated killing of symbiont cell + 5
            regulation of response to cell cycle checkpoint signaling + 3
            regulation of response to tumor cell + 36
            regulation of systemic acquired resistance + 0
            regulation of xenophagy + 10
paths to the root