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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
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Accession:GO:0002824 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.


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positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MALT1 MALT1 paracaspase involved_in IEA UniProt GO_REF:0000117 NCBI chr 1:162,076,933...162,144,915
Ensembl chr 1:162,076,955...162,144,880 		JBrowse link
helper T cell enhancement of adaptive immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD4 CD4 molecule involved_in ISO (PMID:1832488) UniProt PMID:1832488 NCBI chr 5:63,892,129...63,918,547
Ensembl chr 5:63,892,137...63,918,519 		JBrowse link
positive regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:36,465,921...36,471,509
Ensembl chr 7:36,465,324...36,471,516 		JBrowse link
positive regulation of germinal center formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:47,044,492...47,072,232
Ensembl chr17:47,044,497...47,072,245 		JBrowse link
G SLA-DMA SLA-DM alpha chain involved_in ISO (PMID:11714799) BHF-UCL PMID:11714799 NCBI chr 7:25,133,494...25,137,928
Ensembl chr 7:25,133,497...25,137,966 		JBrowse link
G TNFRSF13C TNF receptor superfamily member 13C acts_upstream_of_or_within ISO (PMID:14557413) MGI PMID:14557413 NCBI chr 5:6,699,812...6,703,403
Ensembl chr 5:6,699,878...6,703,656 		JBrowse link
G TNFSF13 TNF superfamily member 13 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chr12:52,853,646...52,857,033
Ensembl chr12:52,853,904...52,857,029 		JBrowse link
G TNFSF13B TNF superfamily member 13b acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:75,599,296...75,633,044
Ensembl chr11:75,599,598...75,633,041 		JBrowse link
positive regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:11934565 RGD:2303774 NCBI chr18:6,363,443...6,371,725 JBrowse link
G HPX hemopexin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:3,288,288...3,297,051
Ensembl chr 9:3,288,172...3,297,047 		JBrowse link
G LTA lymphotoxin alpha acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:23,696,387...23,698,280
Ensembl chr 7:23,696,040...23,698,299 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15692051) MGI PMID:15692051 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,560,073...21,601,308 		JBrowse link
G TNF tumor necrosis factor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415 		JBrowse link
positive regulation of immunoglobulin mediated immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD226 CD226 molecule involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:152,872,878...152,977,162
Ensembl chr 1:152,882,762...152,979,845 		JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:51,317,386...51,358,665 JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (PMID:12496423) BHF-UCL PMID:12496423 NCBI chr 9:115,535,185...115,857,457
Ensembl chr 9:115,550,569...115,659,263 		JBrowse link
positive regulation of immunoglobulin production in mucosal tissue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G XCL1 chemokine (C motif) ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:82,432,845...82,436,150
Ensembl chr 4:82,432,204...82,436,180 		JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFSF4 TNF superfamily member 4 involved_in ISO (PMID:12496423) BHF-UCL PMID:12496423 NCBI chr 9:115,535,185...115,857,457
Ensembl chr 9:115,550,569...115,659,263 		JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXOSC3 exosome component 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:238,536,341...238,541,756
Ensembl chr 1:238,536,345...238,541,333 		JBrowse link
G EXOSC6 exosome component 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:13,295,591...13,296,942
Ensembl chr 6:13,295,125...13,296,914 		JBrowse link
G HMCES 5-hydroxymethylcytosine binding, ES cell specific involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:71,732,311...71,752,296
Ensembl chr13:71,732,277...71,753,486 		JBrowse link
G KMT5B lysine methyltransferase 5B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:4,710,510...4,768,237
Ensembl chr 2:4,711,023...4,765,979 		JBrowse link
G KMT5C lysine methyltransferase 5C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:59,517,058...59,524,551
Ensembl chr 6:59,517,098...59,524,550 		JBrowse link
G MAD2L2 mitotic arrest deficient 2 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:71,773,680...71,779,192
Ensembl chr 6:71,773,154...71,786,517 		JBrowse link
G PAXIP1 PAX interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:3,066,853...3,111,239
Ensembl chr18:3,066,848...3,111,240 		JBrowse link
G RIF1 replication timing regulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:769,518...832,036
Ensembl chr15:774,191...832,010 		JBrowse link
G SHLD1 shieldin complex subunit 1 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr17:14,610,723...14,706,082
Ensembl chr17:14,610,817...14,707,872 		JBrowse link
G SHLD2 shieldin complex subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:88,005,599...88,121,155
Ensembl chr14:88,005,611...88,121,352 		JBrowse link
G TFRC transferrin receptor involved_in ISS
IEA 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:133,976,765...133,997,554
Ensembl chr13:133,970,985...134,000,276 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:127,958,500...128,032,370
Ensembl chr 1:127,959,213...128,028,712 		JBrowse link
G TRAPPC13 trafficking protein particle complex subunit 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:44,146,574...44,186,346
Ensembl chr16:44,156,163...44,184,662 		JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MLH1 mutL homolog 1 involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chr13:21,791,276...21,877,789
Ensembl chr13:21,791,203...21,877,757 		JBrowse link
G MSH2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,585 		JBrowse link
G NSD2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:938,832...1,018,032
Ensembl chr 8:964,893...1,018,028 		JBrowse link
G PMS2 PMS1 homolog 2, mismatch repair system component involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:5,118,002...5,145,634
Ensembl chr 3:5,118,018...5,145,628 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in
acts_upstream_of_or_within 		ISS
IEA 		AgBase
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G TNFSF13 TNF superfamily member 13 involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
UniProt
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr12:52,853,646...52,857,033
Ensembl chr12:52,853,904...52,857,029 		JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCF1 cardiotrophin like cytokine factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:5,142,315...5,152,750
Ensembl chr 2:5,143,313...5,152,692 		JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:22,406,356...22,422,412
Ensembl chr 5:22,406,368...22,421,989 		JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAD5 ATPase family AAA domain containing 5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:42,874,705...42,920,438
Ensembl chr12:42,874,599...42,920,399 		JBrowse link
G CD28 CD28 molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr15:107,128,103...107,155,431
Ensembl chr15:107,128,203...107,162,935 		JBrowse link
G CD40 CD40 molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528 		JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G IL2 interleukin 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12882831), (PMID:14988498) MGI PMID:12882831 PMID:14988498 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G MLH1 mutL homolog 1 involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chr13:21,791,276...21,877,789
Ensembl chr13:21,791,203...21,877,757 		JBrowse link
G MSH2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,585 		JBrowse link
G PAGR1 PAXIP1 associated glutamate rich protein 1 involved_in ISO (PMID:26744420) UniProt PMID:26744420 NCBI chr 3:18,052,679...18,056,920
Ensembl chr 3:18,052,935...18,056,837 		JBrowse link
G PAXIP1 PAX interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:3,066,853...3,111,239
Ensembl chr18:3,066,848...3,111,240 		JBrowse link
G PMS2 PMS1 homolog 2, mismatch repair system component involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:5,118,002...5,145,634
Ensembl chr 3:5,118,018...5,145,628 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,560,073...21,601,308 		JBrowse link
G TBX21 T-box transcription factor 21 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:23,996,415...24,009,353
Ensembl chr12:23,996,415...24,009,355 		JBrowse link
positive regulation of peripheral T cell tolerance induction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,785...43,322,968 		JBrowse link
positive regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2M beta-2-microglobulin involved_in ISO (PMID:24643698) BHF-UCL PMID:24643698 NCBI chr 1:126,837,721...126,844,043
Ensembl chr 1:126,835,143...126,981,582 		JBrowse link
G CD55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) UniProt PMID:16818763 NCBI chr 9:67,933,069...67,960,380
Ensembl chr 9:67,933,220...67,960,370 		JBrowse link
G CD7 CD7 molecule involved_in ISO (PMID:10652336) UniProt PMID:10652336 NCBI chr12:740,345...744,876 JBrowse link
G FZD5 frizzled class receptor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:110,913,990...110,921,388
Ensembl chr15:110,914,009...110,921,353 		JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G MALT1 MALT1 paracaspase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:162,076,933...162,144,915
Ensembl chr 1:162,076,955...162,144,880 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:58,482,046...58,548,087
Ensembl chr 1:58,481,956...58,548,057 		JBrowse link
G SASH3 SAM and SH3 domain containing 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:106,373,871...106,389,454
Ensembl chr  X:106,373,954...106,389,444 		JBrowse link
G SECTM1 secreted and transmembrane 1 involved_in ISO (PMID:22184754) UniProt PMID:22184754 NCBI chr12:730,459...739,899 JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (PMID:18354165), (PMID:9670042) BHF-UCL PMID:9670042 PMID:18354165 NCBI chr 9:115,535,185...115,857,457
Ensembl chr 9:115,550,569...115,659,263 		JBrowse link
G TRAF2 TNF receptor associated factor 2 involved_in IEA Ensembl GO_REF:0000107
G TRAF6 TNF receptor associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:24,602,749...24,628,263
Ensembl chr 2:24,602,804...24,626,072 		JBrowse link
G XCL1 chemokine (C motif) ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:82,432,845...82,436,150
Ensembl chr 4:82,432,204...82,436,180 		JBrowse link
positive regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AZGP1 alpha-2-glycoprotein 1, zinc-binding involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:7,867,521...7,874,857 JBrowse link
G B2M beta-2-microglobulin acts_upstream_of_or_within ISO (PMID:16299293) MGI PMID:16299293 NCBI chr 1:126,837,721...126,844,043
Ensembl chr 1:126,835,143...126,981,582 		JBrowse link
G CD1.1 CD1 antigen involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:91,854,055...91,863,875 JBrowse link
G CD1D CD1d molecule involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:92,096,670...92,101,177
Ensembl chr 4:92,094,700...92,101,095 		JBrowse link
G CD1E CD1e molecule involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:92,012,787...92,019,363
Ensembl chr 4:92,012,791...92,020,864 		JBrowse link
G CYRIB CYFIP related Rac1 interactor B involved_in ISO (PMID:22522492) UniProt PMID:22522492 NCBI chr 4:10,476,137...10,643,395 JBrowse link
G FADD Fas associated via death domain involved_in IEA
ISS 		Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:3,191,718...3,194,820
Ensembl chr 2:3,185,675...3,194,818 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:8871636 RGD:10059395 NCBI chr 9:49,982,278...49,986,760
Ensembl chr 9:49,982,284...49,990,508 		JBrowse link
G IL12A interleukin 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:99,733,394...99,741,078
Ensembl chr13:99,733,394...99,741,078 		JBrowse link
G IL12B interleukin 12B involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:64,143,268...64,158,929
Ensembl chr16:64,143,268...64,158,929 		JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:21,732,416...21,733,981
Ensembl chr 5:21,732,165...21,734,267 		JBrowse link
G LOC100513601 patr class I histocompatibility antigen, A-126 alpha chain-like involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:22,888,616...22,920,154 JBrowse link
G LOC100521998 NKG2D ligand 4-like involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:16,057,036...16,059,787 JBrowse link
G LOC106508817 NKG2D ligand 4-like involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:16,090,757...16,100,784 JBrowse link
G P2RX7 purinergic receptor P2X 7 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:31,415,188...31,476,502
Ensembl chr14:31,415,193...31,476,472 		JBrowse link
G PCD1B CD1B antigen acts_upstream_of_or_within
involved_in 		ISO
IBA 		(PMID:10201995) MGI
GO_Central		 PMID:10201995 GO_REF:0000033 NCBI chr 4:92,035,122...92,040,724
Ensembl chr 4:92,031,712...92,040,742 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,560,073...21,601,308 		JBrowse link
G SLA-11 MHC class I antigen 11 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:23,005,436...23,010,790 JBrowse link
G SLA-7 MHC class I antigen 7 involved_in ISO (PMID:23851683) UniProt PMID:23851683 NCBI chr 7:23,634,731...23,638,722 JBrowse link
G SLA-8 MHC class I antigen 8 acts_upstream_of_or_within ISO (PMID:16299293), (PMID:16461341), (PMID:16476767), (PMID:8464890)
(PMID:16476767) 		MGI PMID:8464890 PMID:16299293 PMID:16461341 PMID:16476767 NCBI chr 7:23,622,352...23,625,818 JBrowse link
G SLA-DRA MHC class II DR-alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:24,825,037...24,830,650
Ensembl chr 7:24,825,052...24,835,158 		JBrowse link
G STX7 syntaxin 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:31,184,905...31,237,052
Ensembl chr 1:31,184,947...31,235,865 		JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of_or_within ISO PMID:1758495
(PMID:16299293)
(PMID:1538753) 		MGI PMID:1538753 PMID:1758495 PMID:16299293 RGD:1299069 NCBI chr 7:25,045,085...25,056,915
Ensembl chr 7:25,043,840...25,056,922 		JBrowse link
G ULBP1 UL16 binding protein 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:16,113,774...16,119,273
Ensembl chr 1:16,113,780...16,119,273 		JBrowse link
G XCL1 chemokine (C motif) ligand 1 involved_in ISO (PMID:18832695) BHF-UCL PMID:18832695 NCBI chr 4:82,432,845...82,436,150
Ensembl chr 4:82,432,204...82,436,180 		JBrowse link
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MR1 major histocompatibility complex, class I-related involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:122,592,510...122,611,462
Ensembl chr 9:122,592,532...122,609,022 		JBrowse link
G SLC22A13 solute carrier family 22 member 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:23,120,013...23,129,183
Ensembl chr13:23,120,222...23,130,829 		JBrowse link
positive regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO38 F-box protein 38 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:149,674,300...149,722,875
Ensembl chr 2:149,674,448...149,722,865 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:101,360,355...101,373,498
Ensembl chr15:101,360,094...101,373,526 		JBrowse link
G KLHL22 kelch like family member 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:50,773,917...50,809,991
Ensembl chr14:50,773,964...50,809,986 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 acts_upstream_of_or_within
involved_in 		IEA
ISO 		(PMID:38377992) Ensembl
UniProt		 PMID:38377992 GO_REF:0000107 NCBI chr16:25,745,902...25,783,524
Ensembl chr16:25,745,324...25,783,707 		JBrowse link
G UFL1 UFM1 specific ligase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:63,638,589...63,698,931
Ensembl chr 1:63,638,596...63,700,476 		JBrowse link
G YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma involved_in ISO (PMID:38377992) UniProt PMID:38377992 NCBI chr 3:9,994,802...10,023,296
Ensembl chr 3:9,994,836...10,023,289 		JBrowse link
positive regulation of T cell mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,560,073...21,601,308 		JBrowse link
G ZBTB1 zinc finger and BTB domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:88,575,563...88,602,726
Ensembl chr 7:88,576,008...88,602,724 		JBrowse link
positive regulation of T-helper 1 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARID5A AT-rich interaction domain 5A involved_in ISO (PMID:27671645) UniProt PMID:27671645 NCBI chr 3:46,701,628...46,714,121
Ensembl chr 3:46,701,632...46,714,113 		JBrowse link
G IL18 interleukin 18 involved_in ISS
IEA 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219 		JBrowse link
G IL18R1 interleukin 18 receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:51,803,383...51,844,758
Ensembl chr 3:51,803,175...51,844,684 		JBrowse link
G IL1B interleukin 1 beta involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:43,670,126...43,677,125 JBrowse link
G IL1R1 interleukin 1 receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,192,912...52,334,734
Ensembl chr 3:52,192,915...52,288,485 		JBrowse link
G LOC110258578 interleukin-1 beta-like involved_in ISO (PMID:10653850) UniProt PMID:10653850
G SLAMF1 signaling lymphocytic activation molecule family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:89,870,359...89,907,114
Ensembl chr 4:89,870,539...89,908,231 		JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,996,415...24,009,353
Ensembl chr12:23,996,415...24,009,355 		JBrowse link
G XCL1 chemokine (C motif) ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:82,432,845...82,436,150
Ensembl chr 4:82,432,204...82,436,180 		JBrowse link
positive regulation of T-helper 1 type immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR2 C-C motif chemokine receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:29,368,735...29,374,564
Ensembl chr13:29,369,122...29,376,343 		JBrowse link
G IL12B interleukin 12B involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:64,143,268...64,158,929
Ensembl chr16:64,143,268...64,158,929 		JBrowse link
G IL12RB1 interleukin 12 receptor subunit beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:59,707,958...59,736,282
Ensembl chr 2:59,707,961...59,736,282 		JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA
IBA 		Ensembl
UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 5:21,732,416...21,733,981
Ensembl chr 5:21,732,165...21,734,267 		JBrowse link
G IL23R interleukin 23 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:145,337,765...145,401,909
Ensembl chr 6:145,335,741...145,401,510 		JBrowse link
G IL27RA interleukin 27 receptor subunit alpha acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:65,127,278...65,149,665
Ensembl chr 2:65,127,287...65,149,740 		JBrowse link
G PLA2G4A phospholipase A2 group IVA involved_in ISO (PMID:16172261) UniProt PMID:16172261 NCBI chr 9:127,853,581...128,164,825
Ensembl chr 9:127,859,051...128,162,638 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:47,026,558...47,075,133
Ensembl chr 4:47,027,098...47,074,704 		JBrowse link
G SLA-DQB1 SLA-DQ beta1 domain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:24,969,034...24,977,238
Ensembl chr 7:24,967,113...24,977,240 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr15:120,434,100...120,446,396
Ensembl chr15:120,433,952...120,446,396 		JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MALT1 MALT1 paracaspase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:162,076,933...162,144,915
Ensembl chr 1:162,076,955...162,144,880 		JBrowse link
G MIR326 microRNA mir-326 acts_upstream_of_or_within ISO (PMID:19838199) MGI PMID:19838199 NCBI chr 9:9,581,944...9,582,034
Ensembl chr 9:9,581,944...9,582,034 		JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chr 6:45,298,289...45,307,471
Ensembl chr 6:45,298,288...45,306,316 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:157,261,419...157,273,119
Ensembl chr13:157,261,419...157,272,688 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (PMID:26098997) UniProt PMID:26098997 NCBI chr 2:56,892,241...56,977,412
Ensembl chr 2:56,892,243...56,977,228 		JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRD2 bromodomain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,096,579...25,162,591
Ensembl chr 7:25,150,564...25,162,584 		JBrowse link
G BRD4 bromodomain containing 4 involved_in ISO (PMID:28262505) UniProt PMID:28262505 NCBI chr 2:62,250,958...62,345,851
Ensembl chr 2:62,250,989...62,345,362 		JBrowse link
G EP300 E1A binding protein p300 acts_upstream_of_or_within
involved_in 		IEA
ISO 		(PMID:28262505) Ensembl
UniProt		 PMID:28262505 GO_REF:0000107 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760 		JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:21,732,416...21,733,981
Ensembl chr 5:21,732,165...21,734,267 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:130,624,771...130,718,345
Ensembl chr13:130,624,796...130,719,083 		JBrowse link
positive regulation of T-helper 17 type immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARID5A AT-rich interaction domain 5A involved_in ISO (PMID:27022145) UniProt PMID:27022145 NCBI chr 3:46,701,628...46,714,121
Ensembl chr 3:46,701,632...46,714,113 		JBrowse link
G CARD9 caspase recruitment domain family member 9 involved_in IEA Ensembl GO_REF:0000107
G CLEC7A C-type lectin domain containing 7A involved_in ISO (PMID:32358020) UniProt PMID:32358020 NCBI chr 5:61,832,910...61,846,441
Ensembl chr 5:61,832,954...61,846,434 		JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:21,732,416...21,733,981
Ensembl chr 5:21,732,165...21,734,267 		JBrowse link
G PRKCQ protein kinase C theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,442,588...64,596,528
Ensembl chr10:64,458,180...64,600,339 		JBrowse link
positive regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:1,625,728...1,641,662
Ensembl chr 2:1,625,736...1,641,663 		JBrowse link
G DENND1B DENN domain containing 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:20,391,507...20,635,808
Ensembl chr10:20,395,481...20,635,748 		JBrowse link
G GATA3 GATA binding protein 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:63,367,684...63,397,977
Ensembl chr10:63,367,663...63,388,859 		JBrowse link
G IL4 interleukin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G IL6 interleukin 6 involved_in ISO (PMID:11159963) BHF-UCL PMID:11159963 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (PMID:26098997) UniProt PMID:26098997 NCBI chr 2:56,892,241...56,977,412
Ensembl chr 2:56,892,243...56,977,228 		JBrowse link
G PRKCZ protein kinase C zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:64,073,343...64,159,187
Ensembl chr 6:64,068,577...64,163,472 		JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 involved_in ISS
IEA 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:128,880,853...128,897,809
Ensembl chr 3:128,877,186...128,897,815 		JBrowse link
G XCL1 chemokine (C motif) ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:82,432,845...82,436,150
Ensembl chr 4:82,432,204...82,436,180 		JBrowse link
positive regulation of type I hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase ISO RGD PMID:22228807 RGD:11040701 NCBI chr  X:82,981,512...83,014,475
Ensembl chr  X:82,981,515...83,014,573 		JBrowse link
G FCER1A Fc epsilon receptor Ia acts_upstream_of_or_within ISO (PMID:8252632) MGI PMID:8252632 NCBI chr 4:91,118,867...91,125,448
Ensembl chr 4:91,118,879...91,125,437 		JBrowse link
G FCER1G Fc epsilon receptor Ig acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:89,242,467...89,246,344
Ensembl chr 4:89,242,472...89,246,450 		JBrowse link
positive regulation of type IIa hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:72,431,470...72,471,622
Ensembl chr 2:72,431,212...72,472,228 		JBrowse link
G FCER1G Fc epsilon receptor Ig acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:89,242,467...89,246,344
Ensembl chr 4:89,242,472...89,246,450 		JBrowse link
G FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:99,233,632...99,242,531
Ensembl chr 4:99,233,611...99,242,586 		JBrowse link
positive regulation of type III hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase ISO RGD PMID:22228807 RGD:11040701 NCBI chr  X:82,981,512...83,014,475
Ensembl chr  X:82,981,515...83,014,573 		JBrowse link
G FCER1G Fc epsilon receptor Ig acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:89,242,467...89,246,344
Ensembl chr 4:89,242,472...89,246,450 		JBrowse link
G FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:99,233,632...99,242,531
Ensembl chr 4:99,233,611...99,242,586 		JBrowse link
positive regulation of type IV hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZP3 zona pellucida glycoprotein 3 involved_in IEA
IDA 		(PMID:15579591) Ensembl
UniProt		 PMID:15579591 GO_REF:0000107 NCBI chr 3:9,934,760...9,944,924
Ensembl chr 3:9,934,760...9,944,941 		JBrowse link
susceptibility to T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NECTIN2 nectin cell adhesion molecule 2 involved_in ISO (PMID:15039383) BHF-UCL PMID:15039383 NCBI chr 6:51,317,386...51,358,665 JBrowse link
G PVR PVR cell adhesion molecule involved_in ISO (PMID:15039383) BHF-UCL PMID:15039383 NCBI chr 6:51,161,320...51,178,464 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19066
    immune system process 2679
      immune response 1782
        positive regulation of immune response 772
          positive regulation of adaptive immune response 132
            positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 126
              helper T cell enhancement of adaptive immune response + 1
              positive regulation of B cell mediated immunity + 45
              positive regulation of T cell mediated immunity + 65
              positive regulation of T-helper 1 type immune response + 19
              positive regulation of T-helper 17 type immune response + 14
              positive regulation of germinal center formation 5
              positive regulation of tolerance induction dependent upon immune response + 1
Path 2
Term Annotations click to browse term
  biological_process 19066
    biological regulation 13066
      regulation of biological process 12689
        positive regulation of biological process 6562
          positive regulation of immune system process 1131
            positive regulation of immune response 772
              positive regulation of adaptive immune response 132
                positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 126
                  helper T cell enhancement of adaptive immune response + 1
                  positive regulation of B cell mediated immunity + 45
                  positive regulation of T cell mediated immunity + 65
                  positive regulation of T-helper 1 type immune response + 19
                  positive regulation of T-helper 17 type immune response + 14
                  positive regulation of germinal center formation 5
                  positive regulation of tolerance induction dependent upon immune response + 1
paths to the root