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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
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Accession:GO:0002824 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.



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helper T cell enhancement of adaptive immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd4 CD4 molecule involved_in ISO (PMID:1832488) UniProt PMID:1832488 NCBI chr 6:23,009,495...23,027,872 JBrowse link
positive regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:30548312) ARUK-UCL PMID:30548312 NCBI chr 4:81,575,823...81,581,791 JBrowse link
positive regulation of germinal center formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (PMID:14607964) MGI PMID:14607964 NCBI chr 5:154,219,332...154,243,553 JBrowse link
G LOC116887425 class II histocompatibility antigen, M alpha chain involved_in ISO (PMID:11714799) BHF-UCL PMID:11714799 NCBI chr18:8,180,772...8,184,189 JBrowse link
G Tnfrsf13c TNF receptor superfamily member 13C acts_upstream_of_or_within ISO (PMID:14557413) MGI PMID:14557413 NCBI chr 1:251,951,579...251,952,857 JBrowse link
G Tnfsf13b TNF superfamily member 13b acts_upstream_of_or_within ISO (PMID:14557413) MGI PMID:14557413 NCBI chr13:73,799,099...73,829,913 JBrowse link
positive regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpx hemopexin acts_upstream_of_or_within ISO (PMID:18641331) MGI PMID:18641331 NCBI chr 2:104,430,172...104,437,915 JBrowse link
G Lta lymphotoxin alpha acts_upstream_of_or_within ISO (PMID:9834074) MGI PMID:9834074 NCBI chr18:7,799,640...7,801,663 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:8566034) MGI PMID:8566034 NCBI chr10:18,430,054...18,543,003 JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:9834074) MGI PMID:9834074 NCBI chr18:7,795,823...7,798,458 JBrowse link
positive regulation of immunoglobulin mediated immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in ISO (PMID:16831868) BHF-UCL PMID:16831868 NCBI chr15:43,493,000...43,567,253 JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO (PMID:16831868) BHF-UCL PMID:16831868 NCBI chr 2:170,868,183...170,902,894 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:12496423) BHF-UCL PMID:12496423 NCBI chr10:40,709,960...40,734,067 JBrowse link
positive regulation of immunoglobulin production in mucosal tissue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C9H17orf99 chromosome 9 C17orf99 homolog involved_in ISO (PMID:28978694) UniProt PMID:28978694 NCBI chr 9:66,257,631...66,269,871 JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:12496423) BHF-UCL PMID:12496423 NCBI chr10:40,709,960...40,734,067 JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 acts_upstream_of_or_within ISO (PMID:21255825) MGI PMID:21255825 NCBI chr 1:1,194,038...1,199,438 JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within ISO (PMID:21255825) MGI PMID:21255825 NCBI chr17:30,750,881...30,752,362 JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISO (PMID:31806351) UniProt PMID:31806351 NCBI chr 6:58,367,167...58,390,355 JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISO (PMID:28114273) UniProt PMID:28114273 NCBI chr 2:3,828,666...3,845,630 JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISO (PMID:28114273) UniProt PMID:28114273 NCBI chr 2:177,315,616...177,323,379 JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr 1:12,635,583...12,648,863 JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:20671152) UniProt PMID:20671152 NCBI chr 6:156,613,816...156,664,878 JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (PMID:23306439), (PMID:23333305), (PMID:23333306) UniProt PMID:23306439 PMID:23333305 PMID:23333306 NCBI chr 5:29,864,927...29,913,417 JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr 5:112,383,780...112,454,371 JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr13:9,995,518...10,028,381 JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chr 3:193,190,234...193,194,904 JBrowse link
G Tfrc transferrin receptor involved_in ISO (PMID:26642240) UniProt PMID:26642240 NCBI chr 4:17,409,729...17,430,431 JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:15077110), (PMID:15159415)
(PMID:23760478)
(PMID:23345425)
UniProt PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 NCBI chr 5:99,352,468...99,449,053 JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chr 8:101,794,931...101,834,789 JBrowse link
G Msh2 mutS homolog 2 involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chr 7:5,259,542...5,317,060 JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (PMID:23241889) MGI PMID:23241889 NCBI chr11:70,948,764...71,022,972 JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chr16:9,244,955...9,268,632 JBrowse link
G Tgfb1 transforming growth factor beta 1 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chr 2:169,090,515...169,108,146 JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin like cytokine factor 1 involved_in ISO (PMID:12023368) BHF-UCL PMID:12023368 NCBI chr 2:3,419,542...3,429,047 JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chr 9:36,098,574...36,104,434 JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO (PMID:10490661) MGI PMID:10490661 NCBI chr 1:206,088,546...206,108,072 JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 acts_upstream_of_or_within ISO (PMID:25404367) MGI PMID:25404367 NCBI chr 9:90,293,627...90,341,150 JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within ISO (PMID:7688139) MGI PMID:7688139 NCBI chr 4:134,828,884...134,854,658 JBrowse link
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chr 5:152,891,252...152,906,394 JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chr 1:196,395,380...196,400,033 JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:1830926) MGI PMID:1830926 NCBI chr 3:116,891,667...116,896,372 JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12882831), (PMID:14988498) MGI PMID:12882831 PMID:14988498 NCBI chr 9:36,098,574...36,104,434 JBrowse link
G Mlh1 mutL homolog 1 involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chr 8:101,794,931...101,834,789 JBrowse link
G Msh2 mutS homolog 2 involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chr 7:5,259,542...5,317,060 JBrowse link
G Pagr1 PAXIP1 associated glutamate rich protein 1 involved_in ISO (PMID:26744420) UniProt PMID:26744420 NCBI chr 2:74,876,388...74,878,376 JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:26744420) UniProt PMID:26744420 NCBI chr 6:156,613,816...156,664,878 JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chr16:9,244,955...9,268,632 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:9015183) MGI PMID:9015183 NCBI chr10:18,430,054...18,543,003 JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chr 9:57,275,432...57,291,934 JBrowse link
positive regulation of peripheral T cell tolerance induction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:16532000) MGI PMID:16532000 NCBI chr  X:14,543,453...14,550,195 JBrowse link
positive regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2-microglobulin involved_in ISO (PMID:24643698) BHF-UCL PMID:24643698 NCBI chr 5:100,253,144...100,259,171 JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) UniProt PMID:16818763 NCBI chr10:5,367,063...5,393,480 JBrowse link
G Cd7 CD7 molecule involved_in ISO (PMID:10652336) UniProt PMID:10652336 NCBI chr 9:62,994,405...62,997,302 JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO (PMID:16601243) CACAO PMID:16601243 NCBI chr 4:138,618,174...138,621,287 JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chr15:65,788,873...65,840,575 JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chr 1:111,003,753...111,061,041 JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within ISO (PMID:16227612) MGI PMID:16227612 NCBI chr  X:110,247,426...110,262,166 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:18354165), (PMID:9670042) BHF-UCL PMID:9670042 PMID:18354165 NCBI chr10:40,709,960...40,734,067 JBrowse link
G Traf2 TNF receptor associated factor 2 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chr 5:11,631,318...11,656,299 JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chr 5:79,516,005...79,535,306 JBrowse link
positive regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2-microglobulin acts_upstream_of_or_within ISO (PMID:16299293) MGI PMID:16299293 NCBI chr 5:100,253,144...100,259,171 JBrowse link
G Cd1d CD1d molecule acts_upstream_of_or_within ISO (PMID:10201995) MGI PMID:10201995 NCBI chr 3:66,569,723...66,573,250 JBrowse link
G Cyrib CYFIP related Rac1 interactor B involved_in ISO (PMID:22522492) UniProt PMID:22522492 NCBI chr 1:238,158,043...238,284,855 JBrowse link
G Fadd Fas associated via death domain involved_in ISO (PMID:21876153) UniProt PMID:21876153 NCBI chr 2:5,142,335...5,145,109 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:8871636 RGD:10059395 NCBI chr 8:35,401,907...35,405,851 JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:1674604), (PMID:2204066) UniProt PMID:1674604 PMID:2204066 NCBI chr 3:86,584,398...86,591,333 JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:14688363) BHF-UCL PMID:14688363 NCBI chr 9:27,231,037...27,240,467 JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:14688363) BHF-UCL PMID:14688363 NCBI chr 1:155,765,926...155,768,132 JBrowse link
G LOC116887285 H-2 class II histocompatibility antigen, E-U alpha chain involved_in ISO (PMID:29884618) UniProt PMID:29884618 NCBI chr18:7,045,134...7,049,182 JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:14761980) MGI PMID:14761980 NCBI chr16:31,142,790...31,183,456 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:6233370) MGI PMID:6233370 NCBI chr10:18,430,054...18,543,003 JBrowse link
G Stx7 syntaxin 7 involved_in ISO (PMID:21438968) UniProt PMID:21438968 NCBI chr 2:210,238,514...210,278,071 JBrowse link
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC116911665 major histocompatibility complex class I-related gene protein involved_in ISO (PMID:31959982) UniProt PMID:31959982 NCBI chr10:34,547,868...34,565,381 JBrowse link
positive regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo38 F-box protein 38 involved_in ISO (PMID:30487606) UniProt PMID:30487606 NCBI chr  X:6,624,264...6,671,057 JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:10663613) BHF-UCL PMID:10663613 NCBI chr 4:129,530,141...129,540,679 JBrowse link
G Klhl22 kelch like family member 22 involved_in ISO (PMID:33109719) UniProt PMID:33109719 NCBI chr 4:3,018,982...3,058,024 JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in ISO (PMID:38377992) UniProt PMID:38377992 NCBI chr 3:175,143,391...175,180,402 JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma involved_in ISO (PMID:38377992) UniProt PMID:38377992 NCBI chr16:18,086,020...18,113,887 JBrowse link
positive regulation of T cell mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:8566034)
(PMID:6233370)
MGI PMID:6233370 PMID:8566034 NCBI chr10:18,430,054...18,543,003 JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 involved_in ISO (PMID:22753936) UniProt PMID:22753936 NCBI chr 7:90,545,401...90,556,837 JBrowse link
positive regulation of T-helper 1 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT-rich interaction domain 5A involved_in ISO (PMID:27671645) UniProt PMID:27671645 NCBI chr 4:112,525,147...112,538,065 JBrowse link
G Il18 interleukin 18 involved_in ISO (PMID:10653850) UniProt PMID:10653850 NCBI chr 8:45,029,011...45,055,185 JBrowse link
G Il18r1 interleukin 18 receptor 1 involved_in ISO (PMID:10653850) UniProt PMID:10653850 NCBI chr 4:116,700,504...116,732,965 JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:10653850) UniProt PMID:10653850 NCBI chr 5:108,109,213...108,115,688 JBrowse link
G Il1r1 interleukin 1 receptor type 1 involved_in ISO (PMID:10653850) UniProt PMID:10653850 NCBI chr 4:116,514,784...116,555,966 JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:9126961) UniProt PMID:9126961 NCBI chr10:50,923,741...50,959,411 JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (PMID:10761931) UniProt PMID:10761931 NCBI chr 9:57,275,432...57,291,934 JBrowse link
positive regulation of T-helper 1 type immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr2 C-C motif chemokine receptor 2 involved_in ISO (PMID:10657654) BHF-UCL PMID:10657654 NCBI chr 8:115,176,474...115,177,595 JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:15114670)
(PMID:14688363)
BHF-UCL PMID:14688363 PMID:15114670 NCBI chr 9:27,231,037...27,240,467 JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 involved_in ISO (PMID:15114670) BHF-UCL PMID:15114670 NCBI chr13:13,051,491...13,063,841 JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:15114670)
(PMID:14688363)
BHF-UCL PMID:14688363 PMID:15114670 NCBI chr 1:155,765,926...155,768,132 JBrowse link
G Il23r interleukin 23 receptor involved_in ISO (PMID:15114670) BHF-UCL PMID:15114670 NCBI chr 6:76,970,947...77,058,358 JBrowse link
G Il27ra interleukin 27 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:11057672) MGI PMID:11057672 NCBI chr17:16,241,637...16,252,615 JBrowse link
G Nlrp10 NLR family pyrin domain containing 10 involved_in ISO (PMID:23071280) UniProt PMID:23071280 NCBI chr 2:92,552,015...92,559,519 JBrowse link
G Pla2g4a phospholipase A2 group IVA involved_in ISO (PMID:16172261) UniProt PMID:16172261 NCBI chr10:29,266,171...29,407,196 JBrowse link
G Slc11a1 solute carrier family 11 member 1 acts_upstream_of_or_within ISO (PMID:18984740) MGI PMID:18984740 NCBI chr 4:147,824,608...147,833,328 JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Malt1 MALT1 paracaspase involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chr15:65,788,873...65,840,575 JBrowse link
G Nfkbid NFKB inhibitor delta involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chr 2:165,572,910...165,580,159 JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chr 4:39,914,855...39,925,700 JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd2 bromodomain containing 2 involved_in ISO (PMID:28262505) UniProt PMID:28262505 NCBI chr18:8,200,198...8,208,944 JBrowse link
G Ep300 EP300 lysine acetyltransferase involved_in ISO (PMID:28262505) UniProt PMID:28262505 NCBI chr 1:251,334,176...251,404,863 JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:19501566) BHF-UCL PMID:19501566 NCBI chr 1:155,765,926...155,768,132 JBrowse link
G Opa1 OPA1 mitochondrial dynamin like GTPase involved_in ISO (PMID:36171294) UniProt PMID:36171294 NCBI chr 4:14,478,312...14,556,210 JBrowse link
positive regulation of T-helper 17 type immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT-rich interaction domain 5A involved_in ISO (PMID:27022145) UniProt PMID:27022145 NCBI chr 4:112,525,147...112,538,065 JBrowse link
G Card9 caspase recruitment domain family member 9 involved_in ISO (PMID:24231284), (PMID:29080677)
(PMID:24470469), (PMID:32358020)
UniProt PMID:24231284 PMID:24470469 PMID:29080677 PMID:32358020 NCBI chr 5:10,727,823...10,736,441 JBrowse link
G Clec6a C-type lectin domain containing 6A involved_in ISO (PMID:32358020) UniProt PMID:32358020 NCBI chr 6:23,997,285...24,012,290 JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:32358020) UniProt PMID:32358020 NCBI chr 6:18,131,910...18,143,037 JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:19501566) BHF-UCL PMID:19501566 NCBI chr 1:155,765,926...155,768,132 JBrowse link
G Nlrp10 NLR family pyrin domain containing 10 involved_in ISO (PMID:23071280) UniProt PMID:23071280 NCBI chr 2:92,552,015...92,559,519 JBrowse link
G Prkcq protein kinase C theta involved_in ISO (PMID:16493044) UniProt PMID:16493044 NCBI chr14:17,200,384...17,331,998 JBrowse link
positive regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 CD81 molecule involved_in ISO (PMID:11046035)
(PMID:8766544)
UniProt PMID:8766544 PMID:11046035 NCBI chr 2:6,635,177...6,651,199 JBrowse link
G Dennd1b DENN domain containing 1B involved_in ISO (PMID:26774822) UniProt PMID:26774822 NCBI chr10:19,318,255...19,530,994 JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (PMID:15087456) MGI PMID:15087456 NCBI chr14:15,891,615...15,911,548 JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:20554961) UniProt PMID:20554961 NCBI chr 9:36,098,574...36,104,434 JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:11159963) BHF-UCL PMID:11159963 NCBI chr 6:158,438,075...158,442,699 JBrowse link
G Prkcz protein kinase C zeta involved_in ISO (PMID:15987782) UniProt PMID:15987782 NCBI chr 1:5,350,189...5,461,946 JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISO (PMID:19047684) UniProt PMID:19047684 NCBI chr 7:39,973,632...39,984,432 JBrowse link
positive regulation of type I hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase ISO RGD PMID:22228807 RGD:11040701 NCBI chr  X:86,848,108...86,886,678 JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia acts_upstream_of_or_within ISO (PMID:8252632) MGI PMID:8252632 NCBI chr10:52,268,876...52,274,929 JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:14764707) MGI PMID:14764707 NCBI chr10:50,394,281...50,398,895 JBrowse link
positive regulation of type IIa hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 acts_upstream_of_or_within ISO (PMID:11901193) MGI PMID:11901193 NCBI chr 4:88,610,382...88,636,268 JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:11901193), (PMID:11911824)
(PMID:8976192)
MGI PMID:8976192 PMID:11901193 PMID:11911824 NCBI chr10:50,394,281...50,398,895 JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia acts_upstream_of_or_within ISO (PMID:11911824) MGI PMID:11911824 NCBI chr 3:60,992,286...61,001,201 JBrowse link
positive regulation of type III hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase ISO RGD PMID:22228807 RGD:11040701 NCBI chr  X:86,848,108...86,886,678 JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:8976192) MGI PMID:8976192 NCBI chr10:50,394,281...50,398,895 JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia acts_upstream_of_or_within ISO (PMID:11911823) MGI PMID:11911823 NCBI chr 3:60,992,286...61,001,201 JBrowse link
positive regulation of type IV hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zp3 zona pellucida glycoprotein 3 involved_in ISO (PMID:15579591) UniProt PMID:15579591 NCBI chr16:18,030,729...18,037,628 JBrowse link
susceptibility to T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO (PMID:15039383) BHF-UCL PMID:15039383 NCBI chr 2:170,868,183...170,902,894 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12423
    immune system process 2015
      immune response 1218
        positive regulation of immune response 627
          positive regulation of adaptive immune response 108
            positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 103
              helper T cell enhancement of adaptive immune response + 1
              positive regulation of B cell mediated immunity + 42
              positive regulation of T cell mediated immunity + 45
              positive regulation of T-helper 1 type immune response + 16
              positive regulation of T-helper 17 type immune response + 13
              positive regulation of germinal center formation 4
              positive regulation of tolerance induction dependent upon immune response + 1
Path 2
Term Annotations click to browse term
  biological_process 12423
    biological regulation 8905
      regulation of biological process 8609
        positive regulation of biological process 5588
          positive regulation of immune system process 943
            positive regulation of immune response 627
              positive regulation of adaptive immune response 108
                positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 103
                  helper T cell enhancement of adaptive immune response + 1
                  positive regulation of B cell mediated immunity + 42
                  positive regulation of T cell mediated immunity + 45
                  positive regulation of T-helper 1 type immune response + 16
                  positive regulation of T-helper 17 type immune response + 13
                  positive regulation of germinal center formation 4
                  positive regulation of tolerance induction dependent upon immune response + 1
paths to the root