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ONTOLOGY REPORT - ANNOTATIONS

Term:immune response-regulating cell surface receptor signaling pathway
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Accession:GO:0002768 term browser browse the term
Definition:The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response.
Synonyms:exact_synonym: immune response-regulating cell surface receptor signalling pathway


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immune response-regulating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTLA B and T lymphocyte associated involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:15568026) InterPro
MGI
TreeGrafter
GO_Central		 PMID:15568026 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:112,463,966...112,499,624
Ensembl chr 3:112,463,966...112,499,472 		JBrowse link
G CD24 CD24 molecule involved_in IC (PMID:11313396) UniProt PMID:11313396 NCBI chr 6:106,969,831...106,976,855
Ensembl chr 6:106,969,831...106,975,627 		JBrowse link
G CD40 CD40 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:15240714) Ensembl
MGI
TreeGrafter
GO_Central		 PMID:15240714 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase involved_in TAS (PMID:8327512) UniProt PMID:8327512 NCBI chr 1:27,612,064...27,635,185
Ensembl chr 1:27,612,064...27,635,185 		JBrowse link
G FPR2 formyl peptide receptor 2 involved_in IDA (PMID:25505240) ARUK-UCL PMID:25505240 NCBI chr19:51,761,180...51,770,531
Ensembl chr19:51,752,026...51,770,531 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA
ISS
TAS		 (PMID:15489917) Ensembl
UniProt		 PMID:15489917 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 ISO RGD PMID:1531699 RGD:2306006 NCBI chr19:6,772,708...6,857,361
Ensembl chr19:6,772,708...6,857,366 		JBrowse link
antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCAR1 BCAR1 scaffold protein, Cas family member involved_in IDA
ISS		 (PMID:10587647) UniProt PMID:10587647 GO_REF:0000024 NCBI chr16:75,228,181...75,268,007
Ensembl chr16:75,228,181...75,268,053 		JBrowse link
G CD19 CD19 molecule involved_in IDA (PMID:1373518) UniProt PMID:1373518 NCBI chr16:28,931,971...28,939,342
Ensembl chr16:28,931,965...28,939,342 		JBrowse link
G LAX1 lymphocyte transmembrane adaptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:15843560) Ensembl
MGI
GO_Central
TreeGrafter		 PMID:15843560 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:203,765,183...203,776,372
Ensembl chr 1:203,765,177...203,776,372 		JBrowse link
G SH2B2 SH2B adaptor protein 2 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:102,285,141...102,321,711
Ensembl chr 7:102,285,091...102,321,711 		JBrowse link
G SLA2 Src like adaptor 2 involved_in TAS (PMID:11696592) UniProt PMID:11696592 NCBI chr20:36,612,318...36,646,196
Ensembl chr20:36,612,318...36,646,196 		JBrowse link
G SPG21 SPG21 abhydrolase domain containing, maspardin involved_in IC (PMID:11113139) UniProt PMID:11113139 NCBI chr15:64,963,022...64,989,914
Ensembl chr15:64,963,022...64,990,310 		JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator involved_in IDA (PMID:15214043) BHF-UCL PMID:15214043 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022 		JBrowse link
B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11120811), (PMID:19228876) Ensembl
MGI		 PMID:11120811 PMID:19228876 GO_REF:0000107 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675 		JBrowse link
G AL121845.2 novel transcript, LIME1-SLC2A4RG readthrough involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 Ensembl chr20:63,738,270...63,740,398 JBrowse link
G AL121845.3 novel protein, ZGPAT-LIME1 readthrough involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 Ensembl chr20:63,708,864...63,739,103 JBrowse link
G BANK1 B cell scaffold protein with ankyrin repeats 1 involved_in TAS (PMID:23555801) ARUK-UCL PMID:23555801 NCBI chr 4:101,790,730...102,074,812
Ensembl chr 4:101,411,286...102,074,812 		JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member involved_in IDA
ISS		 (PMID:9020138) UniProt PMID:9020138 GO_REF:0000024 NCBI chr16:75,228,181...75,268,007
Ensembl chr16:75,228,181...75,268,053 		JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in IMP (PMID:17875758) UniProt PMID:17875758 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase involved_in IDA
IMP		 (PMID:876631)
(PMID:23555801)		 UniProt
ARUK-UCL		 PMID:876631 PMID:23555801 NCBI chr 8:11,494,387...11,564,599
Ensembl chr 8:11,486,894...11,564,599 		JBrowse link
G BLNK B cell linker involved_in IMP
IDA		 (PMID:11606584)
(PMID:9697839)		 ARUK-UCL
UniProt		 PMID:9697839 PMID:11606584 NCBI chr10:96,189,171...96,271,569
Ensembl chr10:96,189,171...96,271,587 		JBrowse link
G BMX BMX non-receptor tyrosine kinase involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr  X:15,500,807...15,556,519
Ensembl chr  X:15,464,246...15,556,529 		JBrowse link
G BTK Bruton tyrosine kinase involved_in IDA
IEA
IBA
TAS		 (PMID:15509800)
(PMID:19290921)		 ARUK-UCL
TreeGrafter
GO_Central
UniProt		 PMID:15509800 PMID:19290921 GO_REF:0000033 GO_REF:0000118 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796 		JBrowse link
G CD19 CD19 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
ISS		 (PMID:9254656) Ensembl
MGI
GO_Central
TreeGrafter
UniProt		 PMID:9254656 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr16:28,931,971...28,939,342
Ensembl chr16:28,931,965...28,939,342 		JBrowse link
G CD38 CD38 molecule involved_in IMP (PMID:17875758) UniProt PMID:17875758 NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232 		JBrowse link
G CD79A CD79a molecule involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
ISS		 (PMID:1373499), (PMID:8626447) Ensembl
MGI
TreeGrafter
GO_Central
InterPro
UniProt		 PMID:1373499 PMID:8626447 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr19:41,877,279...41,881,372
Ensembl chr19:41,877,279...41,881,372 		JBrowse link
G CD79B CD79b molecule involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:1373499), (PMID:8626447) InterPro
MGI
GO_Central
TreeGrafter		 PMID:1373499 PMID:8626447 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr17:63,928,740...63,932,331
Ensembl chr17:63,928,738...63,932,336 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 involved_in IMP
IEA
IBA		 (PMID:17875758) UniProt
TreeGrafter
GO_Central		 PMID:17875758 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G FCRL5 Fc receptor like 5 acts_upstream_of ISO (PMID:23509253) MGI PMID:23509253 NCBI chr 1:157,513,377...157,552,515
Ensembl chr 1:157,513,377...157,552,515 		JBrowse link
G GRB2 growth factor receptor bound protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:75,318,076...75,405,678
Ensembl chr17:75,318,076...75,405,709 		JBrowse link
G IGHA1 immunoglobulin heavy constant alpha 1 involved_in NAS (PMID:20176268) ComplexPortal PMID:20176268 NCBI chr14:105,707,168...105,708,664
Ensembl chr14:105,703,995...105,708,665 		JBrowse link
G IGHA2 immunoglobulin heavy constant alpha 2 (A2m marker) involved_in NAS (PMID:20176268) ComplexPortal PMID:20176268 NCBI chr14:105,586,937...105,588,394
Ensembl chr14:105,583,731...105,588,395 		JBrowse link
G IGHD immunoglobulin heavy constant delta involved_in NAS (PMID:20176268) ComplexPortal PMID:20176268 NCBI chr14:105,838,401...105,845,677
Ensembl chr14:105,836,765...105,845,677 		JBrowse link
G IGHE immunoglobulin heavy constant epsilon involved_in NAS
IDA		 (PMID:20176268)
(PMID:8976175)		 ComplexPortal
UniProt		 PMID:8976175 PMID:20176268 NCBI chr14:105,600,066...105,601,727
Ensembl chr14:105,597,691...105,601,728 		JBrowse link
G IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) involved_in NAS (PMID:20176268) ComplexPortal PMID:20176268 NCBI chr14:105,741,473...105,743,070
Ensembl chr14:105,736,343...105,743,071 		JBrowse link
G IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker) involved_in NAS (PMID:20176268) ComplexPortal PMID:20176268 NCBI chr14:105,643,203...105,644,789
Ensembl chr14:105,639,559...105,644,790 		JBrowse link
G IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker) involved_in NAS (PMID:20176268) ComplexPortal PMID:20176268 NCBI chr14:105,765,914...105,771,405
Ensembl chr14:105,764,503...105,771,405 		JBrowse link
G IGHG4 immunoglobulin heavy constant gamma 4 (G4m marker) involved_in NAS (PMID:20176268) ComplexPortal PMID:20176268 NCBI chr14:105,624,476...105,626,065
Ensembl chr14:105,620,506...105,626,066 		JBrowse link
G IGHM immunoglobulin heavy constant mu involved_in
acts_upstream_of_or_within		 NAS
ISO		 (PMID:20176268)
(PMID:1373499), (PMID:7499277), (PMID:8626447), (PMID:9254656)		 ComplexPortal
MGI		 PMID:1373499 PMID:7499277 PMID:8626447 PMID:9254656 PMID:20176268 NCBI chr14:105,851,966...105,856,217
Ensembl chr14:105,851,705...105,856,218 		JBrowse link
G IGKC immunoglobulin kappa constant involved_in NAS (PMID:20176268) ComplexPortal PMID:20176268 NCBI chr 2:88,857,361...88,857,683
Ensembl chr 2:88,857,161...88,857,683 		JBrowse link
G IGLC1 immunoglobulin lambda constant 1 involved_in NAS (PMID:20176268) ComplexPortal PMID:20176268 NCBI chr22:22,895,375...22,895,694
Ensembl chr22:22,895,375...22,895,834 		JBrowse link
G IGLC3 immunoglobulin lambda constant 3 (Kern-Oz+ marker) involved_in NAS (PMID:20176268) ComplexPortal PMID:20176268 NCBI chr22:22,906,342...22,906,661
Ensembl chr22:22,906,342...22,906,803 		JBrowse link
G IGLC6 immunoglobulin lambda constant 6 involved_in NAS (PMID:20176268) ComplexPortal PMID:20176268 NCBI chr22:22,919,535...22,919,858
Ensembl chr22:22,919,535...22,919,851 		JBrowse link
G IGLC7 immunoglobulin lambda constant 7 involved_in NAS (PMID:20176268) ComplexPortal PMID:20176268 NCBI chr22:22,922,594...22,922,913
Ensembl chr22:22,922,594...22,923,034 		JBrowse link
G ITK IL2 inducible T cell kinase involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:157,180,840...157,255,185
Ensembl chr 5:157,142,933...157,255,185 		JBrowse link
G KLHL6 kelch like family member 6 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 3:183,487,551...183,555,706
Ensembl chr 3:183,487,551...183,555,706 		JBrowse link
G LAT2 linker for activation of T cells family member 2 involved_in IDA
IBA
IEA		 (PMID:12514734) HGNC-UCL
GO_Central
TreeGrafter		 PMID:12514734 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:74,210,006...74,229,834
Ensembl chr 7:74,199,652...74,229,834 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 (PMID:7499277) GO_Central
MGI
TreeGrafter		 PMID:7499277 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:32,251,265...32,286,165
Ensembl chr 1:32,251,244...32,286,165 		JBrowse link
G LIME1 Lck interacting transmembrane adaptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:16249387) InterPro
MGI
GO_Central
TreeGrafter
Ensembl		 PMID:16249387 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr20:63,735,701...63,739,103
Ensembl chr20:63,736,283...63,739,103 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23509253)
(PMID:7499277)		 Ensembl
MGI		 PMID:7499277 PMID:23509253 GO_REF:0000107 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9254656) Ensembl
MGI		 PMID:9254656 GO_REF:0000107 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:88,717,117...88,904,105
Ensembl chr 5:88,717,117...88,904,257 		JBrowse link
G MNDA myeloid cell nuclear differentiation antigen involved_in IMP (PMID:17875758) UniProt PMID:17875758 NCBI chr 1:158,831,351...158,849,502
Ensembl chr 1:158,831,351...158,849,506 		JBrowse link
G MS4A1 membrane spanning 4-domains A1 involved_in IDA (PMID:18474602) UniProt PMID:18474602 NCBI chr11:60,455,847...60,470,752
Ensembl chr11:60,455,846...60,470,752 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IMP (PMID:17875758) UniProt PMID:17875758 NCBI chr12:54,497,752...54,548,243
Ensembl chr12:54,497,752...54,548,243 		JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 (PMID:15143214) GO_Central
MGI
TreeGrafter		 PMID:15143214 GO_REF:0000033 GO_REF:0000118 NCBI chr22:42,380,407...42,437,986
Ensembl chr22:42,380,407...42,432,403 		JBrowse link
G NFATC2 nuclear factor of activated T cells 2 involved_in IMP (PMID:17875758) UniProt PMID:17875758 NCBI chr20:51,386,963...51,562,839
Ensembl chr20:51,386,957...51,562,831 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta involved_in TAS (PMID:20940048) UniProt PMID:20940048 NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in ISS
IDA
IMP
TAS
IEA		 (PMID:15509800)
(PMID:11606584)
(PMID:23555801)		 UniProt
ARUK-UCL
Ensembl		 PMID:11606584 PMID:15509800 PMID:23555801 GO_REF:0000024 GO_REF:0000107 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685 		JBrowse link
G PLEKHA1 pleckstrin homology domain containing A1 involved_in IDA (PMID:12101241) UniProt PMID:12101241 NCBI chr10:122,374,708...122,442,600
Ensembl chr10:122,374,696...122,432,354 		JBrowse link
G PRKCB protein kinase C beta involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23509253)
(PMID:9254656)		 Ensembl
MGI		 PMID:9254656 PMID:23509253 GO_REF:0000107 NCBI chr12:6,946,577...6,961,316
Ensembl chr12:6,946,468...6,961,316 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:9254656)
(PMID:7499277)		 UniProt
MGI
Ensembl		 PMID:7499277 PMID:9254656 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:198,638,713...198,757,476
Ensembl chr 1:198,638,457...198,757,476 		JBrowse link
G RFTN1 raftlin, lipid raft linker 1 involved_in IMP (PMID:12805216) UniProt PMID:12805216 NCBI chr 3:16,315,845...16,513,699
Ensembl chr 3:16,313,574...16,514,026 		JBrowse link
G SH2B2 SH2B adaptor protein 2 involved_in
acts_upstream_of_or_within		 IDA
ISO
IEA		 (PMID:9233773)
(PMID:10872802)		 UniProt
MGI
Ensembl		 PMID:9233773 PMID:10872802 GO_REF:0000107 NCBI chr 7:102,285,141...102,321,711
Ensembl chr 7:102,285,091...102,321,711 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:38,981,549...39,124,868
Ensembl chr 2:38,962,206...39,124,345 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
ISS
IMP		 (PMID:7499277), (PMID:8626447)
(PMID:15509800)		 Ensembl
MGI
GO_Central
TreeGrafter
UniProt
ARUK-UCL		 PMID:7499277 PMID:8626447 PMID:15509800 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
G TEC tec protein tyrosine kinase involved_in IDA
IBA
IEA		 (PMID:10518561) UniProt
GO_Central
TreeGrafter		 PMID:10518561 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:48,135,783...48,269,838
Ensembl chr 4:48,135,783...48,269,838 		JBrowse link
G TMIGD2 transmembrane and immunoglobulin domain containing 2 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr19:4,292,227...4,302,389
Ensembl chr19:4,292,227...4,302,431 		JBrowse link
G TXK TXK tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:48,066,393...48,134,250
Ensembl chr 4:48,066,393...48,134,250 		JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 involved_in IMP (PMID:17875758) UniProt PMID:17875758 NCBI chr 1:107,571,161...107,965,180
Ensembl chr 1:107,571,161...107,965,180 		JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in IDA (PMID:15294986) AgBase PMID:15294986 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CLEC7A C-type lectin domain containing 7A acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
G COLEC10 collectin subfamily member 10 involved_in NAS (PMID:24174618) ComplexPortal PMID:24174618 NCBI chr 8:118,952,263...119,108,455
Ensembl chr 8:118,995,452...119,108,455 		JBrowse link
G COLEC11 collectin subfamily member 11 involved_in NAS (PMID:24174618) ComplexPortal PMID:24174618 NCBI chr 2:3,595,112...3,644,644
Ensembl chr 2:3,594,832...3,644,644 		JBrowse link
G FCN1 ficolin 1 involved_in IMP
NAS		 (PMID:21037097) UniProt
ComplexPortal		 PMID:21037097 NCBI chr 9:134,903,232...134,917,912
Ensembl chr 9:134,903,232...134,917,912 		JBrowse link
G FCN2 ficolin 2 involved_in NAS (PMID:17215869) ComplexPortal PMID:17215869 NCBI chr 9:134,864,144...134,887,523
Ensembl chr 9:134,880,810...134,887,523 		JBrowse link
G FCN3 ficolin 3 involved_in NAS (PMID:17215869) ComplexPortal PMID:17215869 NCBI chr 1:27,369,110...27,374,824
Ensembl chr 1:27,369,110...27,374,824 		JBrowse link
G FFAR2 free fatty acid receptor 2 involved_in IMP (PMID:21037097) UniProt PMID:21037097 NCBI chr19:35,448,257...35,451,767
Ensembl chr19:35,443,907...35,451,767 		JBrowse link
G LBP lipopolysaccharide binding protein involved_in IDA (PMID:15294986) AgBase PMID:15294986 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G MBL2 mannose binding lectin 2 involved_in IDA (PMID:22966085) ComplexPortal PMID:22966085 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
complement component C5a signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3AR1 complement C3a receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chr12:8,056,844...8,066,359
Ensembl chr12:8,056,844...8,066,359 		JBrowse link
G C5AR1 complement C5a receptor 1 involved_in IDA (PMID:10571060) UniProt PMID:10571060 NCBI chr19:47,307,477...47,322,066
Ensembl chr19:47,290,023...47,322,066 		JBrowse link
G C5AR2 complement C5a receptor 2 involved_in IEA GOC GO_REF:0000108 NCBI chr19:47,332,175...47,347,329
Ensembl chr19:47,332,175...47,347,329 		JBrowse link
complement receptor mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G C3AR1 complement C3a receptor 1 involved_in IEA
IBA
IDA		 (PMID:10571060) GOC
GO_Central
UniProt		 PMID:10571060 GO_REF:0000033 GO_REF:0000108 NCBI chr12:8,056,844...8,066,359
Ensembl chr12:8,056,844...8,066,359 		JBrowse link
G C5AR1 complement C5a receptor 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:47,307,477...47,322,066
Ensembl chr19:47,290,023...47,322,066 		JBrowse link
G C5AR2 complement C5a receptor 2 involved_in IEA
IBA		 GOC
GO_Central		 GO_REF:0000033 GO_REF:0000108 NCBI chr19:47,332,175...47,347,329
Ensembl chr19:47,332,175...47,347,329 		JBrowse link
G CMKLR1 chemerin chemokine-like receptor 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:108,288,046...108,339,311
Ensembl chr12:108,288,044...108,339,317 		JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in IDA (PMID:16360013), (PMID:22962438) ARUK-UCL PMID:16360013 PMID:22962438 NCBI chr 1:207,496,157...207,641,765
Ensembl chr 1:207,496,147...207,641,765 		JBrowse link
G CR2 complement C3d receptor 2 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:207,454,328...207,489,892
Ensembl chr 1:207,453,024...207,489,895 		JBrowse link
G FPR1 formyl peptide receptor 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:51,745,172...51,751,878
Ensembl chr19:51,745,172...51,804,115 		JBrowse link
G FPR2 formyl peptide receptor 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:51,761,180...51,770,531
Ensembl chr19:51,752,026...51,770,531 		JBrowse link
G FPR3 formyl peptide receptor 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:51,795,157...51,826,190
Ensembl chr19:51,795,157...51,826,190 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IDA (PMID:15907827), (PMID:19135435) UniProt PMID:15907827 PMID:19135435 NCBI chr 6:24,423,969...24,495,287
Ensembl chr 6:24,424,565...24,495,205 		JBrowse link
G GPR32 G protein-coupled receptor 32 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:50,770,464...50,771,732
Ensembl chr19:50,770,464...50,771,732 		JBrowse link
G GPR32P1 GPR32 pseudogene 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:50,758,233...50,759,501
Ensembl chr19:50,758,382...50,759,192 		JBrowse link
G GPR33 G protein-coupled receptor 33 involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:31,482,875...31,488,039
Ensembl chr14:31,482,875...31,488,039 		JBrowse link
G ITGAM integrin subunit alpha M involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
Fc receptor mediated inhibitory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LILRB1 leukocyte immunoglobulin like receptor B1 involved_in IDA (PMID:9842885) UniProt PMID:9842885 NCBI chr19:54,616,322...54,638,022
Ensembl chr19:54,617,158...54,638,022 		JBrowse link
G LILRB2 leukocyte immunoglobulin like receptor B2 involved_in IDA (PMID:9842885) UniProt PMID:9842885 NCBI chr19:54,273,812...54,281,110
Ensembl chr19:54,273,812...54,281,184 		JBrowse link
G LILRB4 leukocyte immunoglobulin like receptor B4 involved_in IDA (PMID:16493035), (PMID:18420485) ARUK-UCL PMID:16493035 PMID:18420485 NCBI chr19:54,662,985...54,668,718
Ensembl chr19:54,643,889...54,670,359 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G PSG9 pregnancy specific beta-1-glycoprotein 9 involved_in IDA (PMID:27389696) UniProt PMID:27389696 NCBI chr19:43,253,282...43,269,530
Ensembl chr19:43,211,791...43,269,530 		JBrowse link
Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER1G Fc epsilon receptor Ig involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 (PMID:14764707) GO_Central
MGI
TreeGrafter		 PMID:14764707 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:161,215,295...161,219,245
Ensembl chr 1:161,215,234...161,220,699 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
IEA
IBA		 UniProt
TreeGrafter
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
Fc receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD200R1 CD200 receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chr 3:112,921,205...112,975,103
Ensembl chr 3:112,921,205...112,975,103 		JBrowse link
G FCAR Fc alpha receptor involved_in IDA (PMID:25339672) CAFA PMID:25339672 NCBI chr19:54,874,235...54,891,420
Ensembl chr19:54,874,235...54,891,420 		JBrowse link
G FCGR1BP Fc gamma receptor Ib, pseudogene involved_in IEA GOC GO_REF:0000108 NCBI chr 1:121,087,345...121,097,161
Ensembl chr 1:121,087,298...121,097,161
Ensembl chr 1:121,087,298...121,097,161 		JBrowse link
G FCMR Fc mu receptor involved_in IEA GOC GO_REF:0000108 NCBI chr 1:206,903,317...206,923,196
Ensembl chr 1:206,903,317...206,923,247 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase involved_in IEA
IDA		 (PMID:20100931) UniProt
InterPro		 PMID:20100931 GO_REF:0000002 GO_REF:0000104 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,267...54,740,783 		JBrowse link
G PIGR polymeric immunoglobulin receptor involved_in IDA (PMID:22022593) UniProt PMID:22022593 NCBI chr 1:206,928,522...206,946,466
Ensembl chr 1:206,928,522...206,946,466 		JBrowse link
Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796 		JBrowse link
G FCER1A Fc epsilon receptor Ia involved_in IEA GOC GO_REF:0000108 NCBI chr 1:159,283,575...159,308,202
Ensembl chr 1:159,289,714...159,308,224 		JBrowse link
G FCER1G Fc epsilon receptor Ig involved_in IMP
IEA		 (PMID:16735691) UniProt
GOC		 PMID:16735691 GO_REF:0000108 NCBI chr 1:161,215,295...161,219,245
Ensembl chr 1:161,215,234...161,220,699 		JBrowse link
G FCER2 Fc epsilon receptor II involved_in IEA GOC GO_REF:0000108 NCBI chr19:7,688,776...7,702,131
Ensembl chr19:7,688,758...7,702,146 		JBrowse link
G FER FER tyrosine kinase involved_in IEA
IBA
ISS		 Ensembl
TreeGrafter
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:108,747,897...109,196,841
Ensembl chr 5:108,747,841...109,196,841 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G LILRA4 leukocyte immunoglobulin like receptor A4 involved_in IMP (PMID:16735691) UniProt PMID:16735691 NCBI chr19:54,333,185...54,339,162
Ensembl chr19:54,333,185...54,339,162 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr19:7,903,877...7,914,478
Ensembl chr19:7,903,843...7,914,478 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr 5:56,815,549...56,896,152
Ensembl chr 5:56,815,549...56,896,152 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MAPK10 mitogen-activated protein kinase 10 involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr 4:86,010,405...86,594,074
Ensembl chr 4:85,990,007...86,594,625 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G PLCG1 phospholipase C gamma 1 involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685 		JBrowse link
G PRKCQ protein kinase C theta involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr10:6,394,097...6,580,646
Ensembl chr10:6,427,143...6,580,301 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr 2:38,981,549...39,124,868
Ensembl chr 2:38,962,206...39,124,345 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr19:6,772,708...6,857,361
Ensembl chr19:6,772,708...6,857,366 		JBrowse link
G VAV2 vav guanine nucleotide exchange factor 2 involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr 9:133,761,894...133,992,324
Ensembl chr 9:133,761,894...133,992,604 		JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 involved_in TAS Reactome Reactome:R-HSA-2454202 NCBI chr 1:107,571,161...107,965,180
Ensembl chr 1:107,571,161...107,965,180 		JBrowse link
Fc-gamma receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD247 CD247 molecule involved_in IDA (PMID:8478617) UniProt PMID:8478617 NCBI chr 1:167,430,640...167,518,529
Ensembl chr 1:167,425,027...167,518,640 		JBrowse link
G CLEC4D C-type lectin domain family 4 member D involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23602766) Ensembl
MGI		 PMID:23602766 GO_REF:0000107 NCBI chr12:8,513,503...8,531,696
Ensembl chr12:8,509,475...8,522,366 		JBrowse link
G CLEC4E C-type lectin domain family 4 member E involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23602766) Ensembl
MGI		 PMID:23602766 GO_REF:0000107 NCBI chr12:8,533,275...8,540,905
Ensembl chr12:8,533,305...8,540,905 		JBrowse link
G FCER1G Fc epsilon receptor Ig involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:23602766) TreeGrafter
MGI
GO_Central		 PMID:23602766 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:161,215,295...161,219,245
Ensembl chr 1:161,215,234...161,220,699 		JBrowse link
G FCGR1A Fc gamma receptor Ia involved_in IEA GOC GO_REF:0000108 NCBI chr 1:149,782,694...149,800,609
Ensembl chr 1:149,782,671...149,791,675 		JBrowse link
G FCGR1BP Fc gamma receptor Ib, pseudogene involved_in IEA GOC GO_REF:0000108 NCBI chr 1:121,087,345...121,097,161
Ensembl chr 1:121,087,298...121,097,161
Ensembl chr 1:121,087,298...121,097,161 		JBrowse link
G FCGR2A Fc gamma receptor IIa involved_in IEA GOC GO_REF:0000108 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013 		JBrowse link
G FCGR2B Fc gamma receptor IIb involved_in IDA
IEA		 (PMID:2142460) ARUK-UCL
GOC		 PMID:2142460 GO_REF:0000108 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654 		JBrowse link
G FCGR2C Fc gamma receptor IIc (gene/pseudogene) involved_in IEA GOC GO_REF:0000108 NCBI chr 1:161,581,339...161,601,220
Ensembl chr 1:161,581,339...161,605,662 		JBrowse link
G FCGR3A Fc gamma receptor IIIa involved_in IDA (PMID:23024279), (PMID:8478617) UniProt PMID:8478617 PMID:23024279 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968 		JBrowse link
G FCGR3B Fc gamma receptor IIIb involved_in IEA GOC GO_REF:0000108 NCBI chr 1:161,623,196...161,631,963
Ensembl chr 1:161,623,196...161,631,963 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase involved_in IDA (PMID:8478617) UniProt PMID:8478617 NCBI chr 1:32,251,265...32,286,165
Ensembl chr 1:32,251,244...32,286,165 		JBrowse link
G OSCAR osteoclast associated Ig-like receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21841309) Ensembl
MGI		 PMID:21841309 GO_REF:0000107 NCBI chr19:54,094,668...54,100,803
Ensembl chr19:54,094,668...54,102,692 		JBrowse link
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675 		JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 1:27,612,064...27,635,185
Ensembl chr 1:27,612,064...27,635,185 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452 		JBrowse link
G HCK HCK proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr20:32,052,242...32,101,856
Ensembl chr20:32,052,197...32,101,856 		JBrowse link
G LIMK1 LIM domain kinase 1 involved_in TAS Reactome Reactome:R-HSA-2029480 NCBI chr 7:74,083,804...74,122,525
Ensembl chr 7:74,082,933...74,122,525 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MYO1G myosin IG involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:44,962,662...44,979,015
Ensembl chr 7:44,962,662...44,979,088 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 involved_in TAS Reactome Reactome:R-HSA-2029480 NCBI chr11:77,322,017...77,530,009
Ensembl chr11:77,322,017...77,474,635 		JBrowse link
G PLA2G6 phospholipase A2 group VI involved_in TAS Reactome Reactome:R-HSA-2029480 NCBI chr22:38,111,495...38,181,830
Ensembl chr22:38,111,495...38,214,778 		JBrowse link
G PLD2 phospholipase D2 involved_in TAS Reactome Reactome:R-HSA-2029480 NCBI chr17:4,807,152...4,823,430
Ensembl chr17:4,807,152...4,823,434 		JBrowse link
G PLPP4 phospholipid phosphatase 4 involved_in TAS Reactome Reactome:R-HSA-2029480 NCBI chr10:120,456,954...120,592,065
Ensembl chr10:120,457,227...120,592,065 		JBrowse link
G PRKCD protein kinase C delta involved_in TAS Reactome Reactome:R-HSA-2029480 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717 		JBrowse link
G PRKCE protein kinase C epsilon involved_in TAS Reactome Reactome:R-HSA-2029480 NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990 		JBrowse link
G PTK2 protein tyrosine kinase 2 involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr19:6,772,708...6,857,361
Ensembl chr19:6,772,708...6,857,366 		JBrowse link
G VAV2 vav guanine nucleotide exchange factor 2 involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 9:133,761,894...133,992,324
Ensembl chr 9:133,761,894...133,992,604 		JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 1:107,571,161...107,965,180
Ensembl chr 1:107,571,161...107,965,180 		JBrowse link
G YES1 YES proto-oncogene 1, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr18:721,588...812,753
Ensembl chr18:721,588...812,546 		JBrowse link
immune response-activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG6 BAG cochaperone 6 involved_in IDA (PMID:18852879) UniProt PMID:18852879 NCBI chr 6:31,639,028...31,652,661
Ensembl chr 6:31,639,028...31,652,705 		JBrowse link
G MICB MHC class I polypeptide-related sequence B involved_in IDA (PMID:11491531) UniProt PMID:11491531 NCBI chr 6:31,494,918...31,511,124
Ensembl chr 6:31,494,881...31,511,124 		JBrowse link
G NCR3 natural cytotoxicity triggering receptor 3 involved_in IEA
IBA
IDA		 (PMID:18852879) InterPro
TreeGrafter
GO_Central
UniProt		 PMID:18852879 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:31,588,895...31,593,006
Ensembl chr 6:31,588,895...31,593,006 		JBrowse link
immune response-inhibiting cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-G major histocompatibility complex, class I, G involved_in IDA (PMID:20702625) BHF-UCL PMID:20702625 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125 		JBrowse link
G LILRB1 leukocyte immunoglobulin like receptor B1 involved_in NAS (PMID:18550825) BHF-UCL PMID:18550825 NCBI chr19:54,616,322...54,638,022
Ensembl chr19:54,617,158...54,638,022 		JBrowse link
G LILRB2 leukocyte immunoglobulin like receptor B2 involved_in IMP
IDA		 (PMID:14971032)
(PMID:20702625)		 BHF-UCL PMID:14971032 PMID:20702625 NCBI chr19:54,273,812...54,281,110
Ensembl chr19:54,273,812...54,281,184 		JBrowse link
innate immune response activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LILRA2 leukocyte immunoglobulin like receptor A2 involved_in IDA (PMID:27572839) UniProt PMID:27572839 NCBI chr19:54,572,988...54,590,287
Ensembl chr19:54,572,920...54,590,287 		JBrowse link
MyD88-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRFIP2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chr 3:37,052,626...37,176,360
Ensembl chr 3:37,052,626...37,183,689 		JBrowse link
natural killer cell inhibitory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC12B C-type lectin domain family 12 member B involved_in IMP
IEA
IBA		 (PMID:17562706) UniProt
TreeGrafter
GO_Central		 PMID:17562706 GO_REF:0000033 GO_REF:0000118 NCBI chr12:10,006,209...10,018,800
Ensembl chr12:10,010,627...10,018,796 		JBrowse link
G KIR2DL1 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 involved_in IDA (PMID:18604210) UniProt PMID:18604210 NCBI chr19:54,769,793...54,784,322
Ensembl chr19:54,769,793...54,784,322 		JBrowse link
G KLRC1 killer cell lectin like receptor C1 involved_in IDA (PMID:9485206) UniProt PMID:9485206 NCBI chr12:10,442,264...10,454,685
Ensembl chr12:10,442,264...10,454,685 		JBrowse link
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD22 CD22 molecule involved_in IDA
IBA
IEA
TAS
IMP		 (PMID:26017478)
(PMID:15240561)
(PMID:24169826)		 ARUK-UCL
GO_Central
TreeGrafter		 PMID:15240561 PMID:24169826 PMID:26017478 GO_REF:0000033 GO_REF:0000118 NCBI chr19:35,329,187...35,347,361
Ensembl chr19:35,319,261...35,347,361 		JBrowse link
G CD300A CD300a molecule involved_in IDA (PMID:21482706) UniProt PMID:21482706 NCBI chr17:74,466,373...74,484,798
Ensembl chr17:74,466,399...74,484,794 		JBrowse link
G FCGR2B Fc gamma receptor IIb involved_in IMP (PMID:24169826) ARUK-UCL PMID:24169826 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654 		JBrowse link
G FCRL3 Fc receptor like 3 involved_in IDA (PMID:19843936) UniProt PMID:19843936 NCBI chr 1:157,676,481...157,700,956
Ensembl chr 1:157,674,321...157,700,769 		JBrowse link
G FCRL5 Fc receptor like 5 acts_upstream_of_or_within ISO (PMID:23509253) MGI PMID:23509253 NCBI chr 1:157,513,377...157,552,515
Ensembl chr 1:157,513,377...157,552,515 		JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:7,312,661...7,315,360
Ensembl chr17:7,311,324...7,315,564 		JBrowse link
G LPXN leupaxin involved_in IDA
IBA
IEA		 (PMID:17640867) UniProt
GO_Central
Ensembl		 PMID:17640867 GO_REF:0000033 GO_REF:0000107 NCBI chr11:58,526,871...58,578,891
Ensembl chr11:58,526,871...58,578,220 		JBrowse link
G MIR34A microRNA 34a involved_in IDA (PMID:30111844) ARUK-UCL PMID:30111844 NCBI chr 1:9,151,668...9,151,777
Ensembl chr 1:9,151,668...9,151,777 		JBrowse link
G PLCL2 phospholipase C like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14517301) Ensembl
MGI		 PMID:14517301 GO_REF:0000107 NCBI chr 3:16,884,955...17,090,606
Ensembl chr 3:16,802,651...17,090,604 		JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:57,227,729...57,273,471
Ensembl chr 3:57,227,726...57,278,105 		JBrowse link
negative regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTN2A2 butyrophilin subfamily 2 member A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23589618) Ensembl
MGI		 PMID:23589618 GO_REF:0000107 NCBI chr 6:26,383,108...26,394,874
Ensembl chr 6:26,383,096...26,394,874 		JBrowse link
G BTNL2 butyrophilin like 2 acts_upstream_of_or_within ISO (PMID:16751379) MGI PMID:16751379 NCBI chr 6:32,393,339...32,407,181
Ensembl chr 6:32,393,339...32,407,181 		JBrowse link
G CBLB Cbl proto-oncogene B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14738763) Ensembl
MGI		 PMID:14738763 GO_REF:0000107 NCBI chr 3:105,655,461...105,869,449
Ensembl chr 3:105,655,461...105,869,552 		JBrowse link
G CD160 CD160 molecule involved_in IDA (PMID:18193050) UniProt PMID:18193050 NCBI chr 1:145,719,499...145,739,288
Ensembl chr 1:145,719,471...145,739,288 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in IDA (PMID:18424730) UniProt PMID:18424730 NCBI chr19:42,507,306...42,528,481
Ensembl chr19:42,507,304...42,561,234 		JBrowse link
G DGKZ diacylglycerol kinase zeta involved_in ISS UniProt GO_REF:0000024 NCBI chr11:46,332,926...46,380,554
Ensembl chr11:46,332,905...46,380,554 		JBrowse link
G DUSP22 dual specificity phosphatase 22 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24714587) Ensembl
MGI		 PMID:24714587 GO_REF:0000107 NCBI chr 6:292,487...351,355
Ensembl chr 6:291,630...351,355 		JBrowse link
G DUSP3 dual specificity phosphatase 3 involved_in IDA
IEA
IBA		 (PMID:12447358) UniProt
TreeGrafter
GO_Central		 PMID:12447358 GO_REF:0000033 GO_REF:0000118 NCBI chr17:43,766,125...43,778,977
Ensembl chr17:43,766,125...43,778,977 		JBrowse link
G ELF1 E74 like ETS transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14738763) Ensembl
MGI		 PMID:14738763 GO_REF:0000107 NCBI chr13:40,931,919...41,061,386
Ensembl chr13:40,931,924...41,061,440 		JBrowse link
G EZR ezrin involved_in IMP (PMID:20551903) UniProt PMID:20551903 NCBI chr 6:158,765,748...158,819,368
Ensembl chr 6:158,765,741...158,819,368 		JBrowse link
G GBP1 guanylate binding protein 1 involved_in IMP (PMID:24337748) UniProt PMID:24337748 NCBI chr 1:89,052,319...89,065,208
Ensembl chr 1:89,051,882...89,065,360 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISS (PMID:8661146) ARUK-UCL PMID:8661146 NCBI chr 1:30,732,469...30,757,774
Ensembl chr 1:30,732,469...30,757,774 		JBrowse link
G LGALS3 galectin 3 involved_in ISS (PMID:19706535) BHF-UCL PMID:19706535 NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423 		JBrowse link
G LILRB4 leukocyte immunoglobulin like receptor B4 involved_in IDA
IMP		 (PMID:22387553)
(PMID:16493035)		 BHF-UCL
ARUK-UCL		 PMID:16493035 PMID:22387553 NCBI chr19:54,662,985...54,668,718
Ensembl chr19:54,643,889...54,670,359 		JBrowse link
G LOC124907782 dual specificity protein phosphatase 22 involved_in IEA Ensembl GO_REF:0000107
G PAWR pro-apoptotic WT1 regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12970181) Ensembl
MGI		 PMID:12970181 GO_REF:0000107 NCBI chr12:79,584,879...79,690,964
Ensembl chr12:79,574,979...79,690,964 		JBrowse link
G PHPT1 phosphohistidine phosphatase 1 involved_in IMP (PMID:18796614) BHF-UCL PMID:18796614 NCBI chr 9:136,849,409...136,851,024
Ensembl chr 9:136,848,724...136,851,027 		JBrowse link
G PRNP prion protein (Kanno blood group) involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr18:12,785,478...12,884,237
Ensembl chr18:12,785,478...12,929,643 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IDA (PMID:18056643) UniProt PMID:18056643 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9064344) Ensembl
MGI		 PMID:9064344 GO_REF:0000107 NCBI chr12:6,946,577...6,961,316
Ensembl chr12:6,946,468...6,961,316 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in IMP
IEA
IDA		 (PMID:11259588), (PMID:9780142)
(PMID:12913111)		 UniProt
Ensembl		 PMID:9780142 PMID:11259588 PMID:12913111 GO_REF:0000107 NCBI chr11:47,980,559...48,170,839
Ensembl chr11:47,980,425...48,170,839 		JBrowse link
G PVRIG PVR related immunoglobulin domain containing involved_in IMP
IBA
IEA		 (PMID:26755705) UniProt
GO_Central
TreeGrafter
InterPro		 PMID:26755705 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:100,219,248...100,221,490
Ensembl chr 7:100,218,241...100,221,490 		JBrowse link
G SH2D1A SH2 domain containing 1A involved_in IDA (PMID:9774102) UniProt PMID:9774102 NCBI chr  X:124,346,563...124,373,160
Ensembl chr  X:124,227,868...124,373,197 		JBrowse link
G SLA2 Src like adaptor 2 involved_in IMP (PMID:11891219) UniProt PMID:11891219 NCBI chr20:36,612,318...36,646,196
Ensembl chr20:36,612,318...36,646,196 		JBrowse link
G THY1 Thy-1 cell surface antigen involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:119,415,476...119,424,985
Ensembl chr11:119,415,476...119,424,985 		JBrowse link
G UBASH3A ubiquitin associated and SH3 domain containing A involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:14738763) Ensembl
MGI
TreeGrafter
GO_Central		 PMID:14738763 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr21:42,403,902...42,447,684
Ensembl chr21:42,403,447...42,447,684 		JBrowse link
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IMP
IEA		 (PMID:26599367) UniProt
Ensembl		 PMID:26599367 GO_REF:0000107 NCBI chr 8:8,783,354...8,893,630
Ensembl chr 8:8,783,354...8,893,630 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15220916) Ensembl
MGI		 PMID:15220916 GO_REF:0000107 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G TLR6 toll like receptor 6 involved_in IGI (PMID:22198949) ARUK-UCL PMID:22198949 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in NAS (PMID:15142865) BHF-UCL PMID:15142865 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638 		JBrowse link
G BPIFB1 BPI fold containing family B member 1 involved_in IDA
IBA
IEA		 (PMID:21900486) UniProt
GO_Central
TreeGrafter		 PMID:21900486 GO_REF:0000033 GO_REF:0000118 NCBI chr20:33,283,214...33,309,871
Ensembl chr20:33,273,480...33,309,871 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IDA (PMID:19948740) UniProt PMID:19948740 NCBI chr 9:121,567,074...121,785,530
Ensembl chr 9:121,567,057...121,785,530 		JBrowse link
G LILRA2 leukocyte immunoglobulin like receptor A2 involved_in IMP (PMID:22479404) UniProt PMID:22479404 NCBI chr19:54,572,988...54,590,287
Ensembl chr19:54,572,920...54,590,287 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IMP (PMID:28609714) UniProt PMID:28609714 NCBI chr 8:8,783,354...8,893,630
Ensembl chr 8:8,783,354...8,893,630 		JBrowse link
G MIR140 microRNA 140 involved_in IGI
IMP		 (PMID:30321456)
(PMID:30233718)		 ARUK-UCL PMID:30233718 PMID:30321456 NCBI chr16:69,933,081...69,933,180
Ensembl chr16:69,933,081...69,933,180 		JBrowse link
G MIR146A microRNA 146a involved_in IC (PMID:21329689) ARUK-UCL PMID:21329689 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450 		JBrowse link
G MIR149 microRNA 149 involved_in IMP (PMID:28260877) ARUK-UCL PMID:28260877 NCBI chr 2:240,456,001...240,456,089
Ensembl chr 2:240,456,001...240,456,089 		JBrowse link
G MIR200B microRNA 200b involved_in IDA (PMID:22522429) ARUK-UCL PMID:22522429 NCBI chr 1:1,167,104...1,167,198
Ensembl chr 1:1,167,104...1,167,198 		JBrowse link
G MIR200C microRNA 200c involved_in IDA (PMID:22522429) ARUK-UCL PMID:22522429 NCBI chr12:6,963,699...6,963,766
Ensembl chr12:6,963,699...6,963,766 		JBrowse link
G MIR20A microRNA 20a involved_in IDA (PMID:29653364) ARUK-UCL PMID:29653364 NCBI chr13:91,351,065...91,351,135
Ensembl chr13:91,351,065...91,351,135 		JBrowse link
G MIR708 microRNA 708 involved_in IMP (PMID:31599428) ARUK-UCL PMID:31599428 NCBI chr11:79,402,022...79,402,109
Ensembl chr11:79,402,022...79,402,109 		JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in IMP (PMID:18511497) BHF-UCL PMID:18511497 NCBI chr17:40,092,793...40,100,589
Ensembl chr17:40,092,793...40,100,589 		JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:205,976,740...206,003,395
Ensembl chr 1:205,976,740...206,003,461 		JBrowse link
G SQSTM1 sequestosome 1 involved_in IDA (PMID:31281713) UniProt PMID:31281713 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 involved_in IDA (PMID:28898289) UniProt PMID:28898289 NCBI chr 7:27,739,373...27,829,767
Ensembl chr 7:27,739,331...27,844,564 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IDA (PMID:19412184) UniProt PMID:19412184 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TMED7-TICAM2 TMED7-TICAM2 readthrough involved_in IDA (PMID:19412184) UniProt PMID:19412184 NCBI chr 5:115,578,496...115,626,036
Ensembl chr 5:115,578,642...115,626,161 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in NAS (PMID:15142865) BHF-UCL PMID:15142865 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
G TRIM32 tripartite motif containing 32 involved_in IDA (PMID:28898289) UniProt PMID:28898289 NCBI chr 9:116,687,305...116,701,299
Ensembl chr 9:116,687,305...116,701,300 		JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPRC protein tyrosine phosphatase receptor type C involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:198,638,713...198,757,476
Ensembl chr 1:198,638,457...198,757,476 		JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule involved_in IMP
ISS
IEA		 (PMID:20237408) UniProt
Ensembl		 PMID:20237408 GO_REF:0000024 GO_REF:0000107 NCBI chr11:2,376,180...2,397,397
Ensembl chr11:2,376,177...2,397,802 		JBrowse link
G CMTM3 CKLF like MARVEL transmembrane domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15196959) Ensembl
MGI		 PMID:15196959 GO_REF:0000107 NCBI chr16:66,603,996...66,613,892
Ensembl chr16:66,603,874...66,613,892 		JBrowse link
G FOXP1 forkhead box P1 involved_in IMP (PMID:30111844) ARUK-UCL PMID:30111844 NCBI chr 3:70,954,708...71,583,978
Ensembl chr 3:70,954,693...71,583,978 		JBrowse link
G MIR18A microRNA 18a involved_in IDA (PMID:24169826) ARUK-UCL PMID:24169826 NCBI chr13:91,350,751...91,350,821
Ensembl chr13:91,350,751...91,350,821 		JBrowse link
G MIR19A microRNA 19a involved_in IDA (PMID:24169826), (PMID:26017478) ARUK-UCL PMID:24169826 PMID:26017478 NCBI chr13:91,350,891...91,350,972
Ensembl chr13:91,350,891...91,350,972 		JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 involved_in IEA
ISS		 (PMID:15143214) InterPro
HGNC-UCL		 PMID:15143214 GO_REF:0000002 NCBI chr22:42,380,407...42,437,986
Ensembl chr22:42,380,407...42,432,403 		JBrowse link
G PRKCB protein kinase C beta involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611 		JBrowse link
G PRKCH protein kinase C eta involved_in IMP (PMID:18780722) UniProt PMID:18780722 NCBI chr14:61,187,468...61,550,976
Ensembl chr14:61,187,559...61,550,976 		JBrowse link
G SLC39A10 solute carrier family 39 member 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25074919) Ensembl
MGI		 PMID:25074919 GO_REF:0000107 NCBI chr 2:195,613,029...195,737,700
Ensembl chr 2:195,575,977...195,737,702 		JBrowse link
G STAP1 signal transducing adaptor family member 1 involved_in IDA
IBA
IEA		 (PMID:10518561) BHF-UCL
GO_Central
TreeGrafter		 PMID:10518561 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:67,558,727...67,607,337
Ensembl chr 4:67,558,727...67,607,337 		JBrowse link
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD226 CD226 molecule involved_in IDA
IEA
IBA		 (PMID:16831868) BHF-UCL
TreeGrafter
GO_Central		 PMID:16831868 GO_REF:0000033 GO_REF:0000118 NCBI chr18:69,853,274...69,961,773
Ensembl chr18:69,831,158...69,961,803 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in ISO
IEA		 RGD
Ensembl		 PMID:16177098 GO_REF:0000107 RGD:1578516 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in IEA
ISS		 (PMID:18249142) Ensembl
ARUK-UCL		 PMID:18249142 GO_REF:0000107 NCBI chr 1:198,638,713...198,757,476
Ensembl chr 1:198,638,457...198,757,476 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in ISS
IEA		 (PMID:18249142) ARUK-UCL
Ensembl		 PMID:18249142 GO_REF:0000107 NCBI chr11:47,980,559...48,170,839
Ensembl chr11:47,980,425...48,170,839 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO RGD PMID:18832707 RGD:9835043 NCBI chr 1:111,542,009...111,716,691
Ensembl chr 1:111,542,218...111,716,691 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO RGD PMID:18832707 RGD:9835043 NCBI chr 9:131,576,775...131,740,076
Ensembl chr 9:131,576,770...131,740,076 		JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:105,173,300...105,236,174
Ensembl chr12:105,173,297...105,236,203 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:131,576,775...131,740,076
Ensembl chr 9:131,576,770...131,740,076 		JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR4A3 nuclear receptor subfamily 4 group A member 3 involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:99,821,885...99,866,891
Ensembl chr 9:99,821,855...99,866,891 		JBrowse link
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11435465) Ensembl
MGI		 PMID:11435465 GO_REF:0000107 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IDA (PMID:18287044), (PMID:27777308) UniProt PMID:18287044 PMID:27777308 NCBI chr 1:85,265,776...85,276,632
Ensembl chr 1:85,265,776...85,276,632 		JBrowse link
G CARD11 caspase recruitment domain family member 11 involved_in IEA
ISS
IMP		 (PMID:12154360) Ensembl
UniProt		 PMID:12154360 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:2,906,142...3,043,867
Ensembl chr 7:2,906,142...3,044,228 		JBrowse link
G CCR7 C-C motif chemokine receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:40,553,769...40,565,472
Ensembl chr17:40,553,769...40,565,472 		JBrowse link
G CD226 CD226 molecule involved_in IMP
IBA
IEA		 (PMID:26755705) UniProt
GO_Central
TreeGrafter		 PMID:26755705 GO_REF:0000033 GO_REF:0000118 NCBI chr18:69,853,274...69,961,773
Ensembl chr18:69,831,158...69,961,803 		JBrowse link
G CD81 CD81 molecule involved_in IMP (PMID:23858057) UniProt PMID:23858057 NCBI chr11:2,376,180...2,397,397
Ensembl chr11:2,376,177...2,397,802 		JBrowse link
G CYLD CYLD lysine 63 deubiquitinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16501569) Ensembl
MGI		 PMID:16501569 GO_REF:0000107 NCBI chr16:50,742,086...50,801,935
Ensembl chr16:50,742,050...50,801,935 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in IDA (PMID:18287044), (PMID:27777308) UniProt PMID:18287044 PMID:27777308 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,199...154,565,046 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 involved_in IDA (PMID:18796614) BHF-UCL PMID:18796614 NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase involved_in NAS (PMID:12614355) UniProt PMID:12614355 NCBI chr 1:32,251,265...32,286,165
Ensembl chr 1:32,251,244...32,286,165 		JBrowse link
G LIPA lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19179613) Ensembl
MGI		 PMID:19179613 GO_REF:0000107 NCBI chr10:89,213,572...89,251,775
Ensembl chr10:89,213,569...89,414,557 		JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IDA
IEA
IBA		 (PMID:26755705) UniProt
TreeGrafter
GO_Central		 PMID:26755705 GO_REF:0000033 GO_REF:0000118 NCBI chr19:44,846,297...44,889,223
Ensembl chr19:44,846,175...44,889,223 		JBrowse link
G PRKD2 protein kinase D2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:46,674,316...46,717,114
Ensembl chr19:46,674,275...46,717,127 		JBrowse link
G PVR PVR cell adhesion molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:44,643,910...44,666,162
Ensembl chr19:44,643,798...44,666,162 		JBrowse link
G RAB29 RAB29, member RAS oncogene family involved_in IMP (PMID:26021297) ParkinsonsUK-UCL PMID:26021297 NCBI chr 1:205,767,986...205,775,482
Ensembl chr 1:205,767,986...205,775,482 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IMP (PMID:18045535) CAFA PMID:18045535 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RPS3 ribosomal protein S3 involved_in IMP (PMID:18045535) CAFA PMID:18045535 NCBI chr11:75,399,518...75,422,302
Ensembl chr11:75,399,515...75,422,280 		JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 involved_in ISS
IBA
IEA		 UniProt
GO_Central
TreeGrafter
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:54,948,015...54,985,188
Ensembl chr12:54,948,015...54,984,762 		JBrowse link
G TRAT1 T cell receptor associated transmembrane adaptor 1 acts_upstream_of_or_within
involved_in		 IDA
IBA
IEA		 (PMID:11390434) MGI
GO_Central
TreeGrafter		 PMID:11390434 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:108,822,786...108,855,005
Ensembl chr 3:108,822,770...108,855,005 		JBrowse link
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYBA cytochrome b-245 alpha chain involved_in IDA (PMID:22423966) UniProt PMID:22423966 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IMP (PMID:19865078) UniProt PMID:19865078 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (MGI:5788395|PMID:16267105) UniProt PMID:16267105 MGI:5788395 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IMP
IEA		 (PMID:26599367), (PMID:28471450) UniProt
Ensembl		 PMID:26599367 PMID:28471450 GO_REF:0000107 NCBI chr 8:8,783,354...8,893,630
Ensembl chr 8:8,783,354...8,893,630 		JBrowse link
G PJA2 praja ring finger ubiquitin ligase 2 involved_in IMP (PMID:28471450) UniProt PMID:28471450 NCBI chr 5:109,334,722...109,409,974
Ensembl chr 5:109,334,713...109,409,974 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IMP (PMID:19509286) BHF-UCL PMID:19509286 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR1 toll like receptor 1 involved_in IGI (PMID:22198949) ARUK-UCL PMID:22198949 NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,790,677...38,856,817 		JBrowse link
positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC093884.1 novel protein, WDFY1-AP1S3 readthrough involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr 2:223,757,258...223,945,299 JBrowse link
G CD14 CD14 molecule involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IDA (PMID:18622013) UniProt PMID:18622013 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (MGI:5788395|PMID:16267105) UniProt PMID:16267105 MGI:5788395 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G IFI35 interferon induced protein 35 involved_in IDA (PMID:29038465) UniProt PMID:29038465 NCBI chr17:43,006,784...43,014,456
Ensembl chr17:43,006,740...43,014,456 		JBrowse link
G LBP lipopolysaccharide binding protein involved_in IDA (PMID:11528597) BHF-UCL PMID:11528597 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G LTF lactotransferrin involved_in IMP (PMID:20345905) UniProt PMID:20345905 NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234 		JBrowse link
G NINJ1 ninjurin 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:93,121,496...93,134,251
Ensembl chr 9:93,121,496...93,134,251 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IDA (PMID:18511497) BHF-UCL PMID:18511497 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033 		JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19734906) Ensembl
MGI		 PMID:19734906 GO_REF:0000107 NCBI chr 2:64,092,652...64,144,420
Ensembl chr 2:64,092,652...64,144,420 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA
IMP		 (PMID:23871208) Ensembl
TreeGrafter
UniProt		 PMID:23871208 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IDA
IMP		 (PMID:19412184)
(PMID:22685567)		 UniProt PMID:19412184 PMID:22685567 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IMP (PMID:19509286) BHF-UCL PMID:19509286 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TMED7-TICAM2 TMED7-TICAM2 readthrough involved_in IMP
IDA		 (PMID:22685567)
(PMID:19412184)		 UniProt PMID:19412184 PMID:22685567 NCBI chr 5:115,578,496...115,626,036
Ensembl chr 5:115,578,642...115,626,161 		JBrowse link
G WDFY1 WD repeat and FYVE domain containing 1 involved_in IEA
IBA
IMP		 (PMID:25736436) Ensembl
GO_Central
TreeGrafter
UniProt		 PMID:25736436 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:223,875,348...223,945,335
Ensembl chr 2:223,855,716...223,945,357 		JBrowse link
G ZNRF1 zinc and ring finger 1 involved_in IDA (PMID:28593998) UniProt PMID:28593998 NCBI chr16:74,999,024...75,110,994
Ensembl chr16:74,999,024...75,110,994 		JBrowse link
regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD19 CD19 molecule involved_in IEA
IMP		 (PMID:9382888) Ensembl
UniProt		 PMID:9382888 GO_REF:0000107 NCBI chr16:28,931,971...28,939,342
Ensembl chr16:28,931,965...28,939,342 		JBrowse link
G FCMR Fc mu receptor involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:206,903,317...206,923,196
Ensembl chr 1:206,903,317...206,923,247 		JBrowse link
G GCSAM germinal center associated signaling and motility involved_in IEA
IBA
IMP		 (PMID:23299888) InterPro
GO_Central
TreeGrafter
UniProt		 PMID:23299888 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:112,120,839...112,133,248
Ensembl chr 3:112,120,839...112,133,270 		JBrowse link
G GCSAML germinal center associated signaling and motility like involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:247,507,058...247,577,690
Ensembl chr 1:247,507,058...247,577,690 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA
IBA
ISS		 Ensembl
TreeGrafter
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in NAS (PMID:19265110) BHF-UCL PMID:19265110 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD47 CD47 molecule involved_in ISS (PMID:21401967) ARUK-UCL PMID:21401967 NCBI chr 3:108,043,091...108,091,031
Ensembl chr 3:108,043,091...108,091,862 		JBrowse link
G CSK C-terminal Src kinase involved_in ISO
IBA
IEA		 RGD
GO_Central
TreeGrafter
Ensembl		 PMID:9325302 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:2303720 NCBI chr15:74,782,080...74,803,197
Ensembl chr15:74,782,080...74,803,197 		JBrowse link
G FCGR2A Fc gamma receptor IIa ISO RGD PMID:16482158 PMID:22184119 RGD:11041001 RGD:2293335 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013 		JBrowse link
G PLSCR1 phospholipid scramblase 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:146,515,180...146,544,607
Ensembl chr 3:146,515,180...146,544,856 		JBrowse link
G PTEN phosphatase and tensin homolog ISO negative regulation RGD PMID:18056380 RGD:2292524 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G RABGEF1 RAB guanine nucleotide exchange factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15235600)
(PMID:17341663)		 Ensembl
MGI		 PMID:15235600 PMID:17341663 GO_REF:0000107 NCBI chr 7:66,654,567...66,811,464
Ensembl chr 7:66,682,164...66,811,464 		JBrowse link
regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL10 BCL10 immune signaling adaptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14614861) Ensembl
MGI		 PMID:14614861 GO_REF:0000107 NCBI chr 1:85,265,776...85,276,632
Ensembl chr 1:85,265,776...85,276,632 		JBrowse link
G CD300A CD300a molecule involved_in IDA (PMID:22046970) UniProt PMID:22046970 NCBI chr17:74,466,373...74,484,798
Ensembl chr17:74,466,399...74,484,794 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:14752163) MGI PMID:14752163 NCBI chr 1:32,251,265...32,286,165
Ensembl chr 1:32,251,244...32,286,165 		JBrowse link
G MALT1 MALT1 paracaspase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14614861) Ensembl
MGI		 PMID:14614861 GO_REF:0000107 NCBI chr18:58,671,465...58,754,477
Ensembl chr18:58,671,465...58,754,477 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:173,931,084...174,022,357
Ensembl chr 1:173,931,084...174,022,357 		JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:28598420) Ensembl
MGI		 PMID:28598420 GO_REF:0000107 NCBI chr12:54,948,015...54,985,188
Ensembl chr12:54,948,015...54,984,762 		JBrowse link
regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:57,227,729...57,273,471
Ensembl chr 3:57,227,726...57,278,105 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:105,173,300...105,236,174
Ensembl chr12:105,173,297...105,236,203 		JBrowse link
G FLOT1 flotillin 1 NOT|involved_in IMP (PMID:25204797) UniProt PMID:25204797 NCBI chr 6:30,727,709...30,742,687
Ensembl chr 6:30,727,709...30,742,732 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IDA (PMID:19289601) UniProt PMID:19289601 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
regulation of toll-like receptor 6 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC6A C-type lectin domain containing 6A involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:8,455,962...8,478,330
Ensembl chr12:8,455,962...8,478,330 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
G CREBBP CREB binding protein involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713 		JBrowse link
G EP300 E1A binding protein p300 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G KLRC1 killer cell lectin like receptor C1 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr12:10,442,264...10,454,685
Ensembl chr12:10,442,264...10,454,685 		JBrowse link
G KLRC2 killer cell lectin like receptor C2 involved_in IDA
IEA
IBA		 (PMID:9655483) UniProt
TreeGrafter
GO_Central		 PMID:9655483 GO_REF:0000033 GO_REF:0000118 NCBI chr12:10,430,599...10,436,010
Ensembl chr12:10,426,854...10,442,300 		JBrowse link
G KLRC3 killer cell lectin like receptor C3 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr12:10,412,315...10,420,595
Ensembl chr12:10,412,315...10,420,595 		JBrowse link
G KLRC4 killer cell lectin like receptor C4 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr12:10,407,384...10,409,757
Ensembl chr12:10,407,384...10,409,757 		JBrowse link
G KLRC4-KLRK1 KLRC4-KLRK1 readthrough involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:10,372,353...10,410,146
Ensembl chr12:10,372,353...10,410,146
Ensembl chr12:10,372,353...10,410,146 		JBrowse link
G KLRD1 killer cell lectin like receptor D1 involved_in IDA
IEA
IBA		 (PMID:9655483) UniProt
TreeGrafter
GO_Central		 PMID:9655483 GO_REF:0000033 GO_REF:0000118 NCBI chr12:10,238,961...10,329,608
Ensembl chr12:10,226,058...10,329,608 		JBrowse link
G KLRK1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12645935) Ensembl
MGI		 PMID:12645935 GO_REF:0000107 NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr11:77,322,017...77,530,009
Ensembl chr11:77,322,017...77,474,635 		JBrowse link
G PAK2 p21 (RAC1) activated kinase 2 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr 3:196,739,857...196,832,647
Ensembl chr 3:196,739,857...196,832,647 		JBrowse link
G PAK3 p21 (RAC1) activated kinase 3 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr  X:110,944,397...111,227,361
Ensembl chr  X:110,944,285...111,227,361 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in ISS
TAS
IEA		 ARUK-UCL
Reactome
Ensembl		 GO_REF:0000024 GO_REF:0000107 Reactome:R-HSA-5621481 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in ISS
IEA
TAS		 ARUK-UCL
Ensembl
Reactome		 GO_REF:0000024 GO_REF:0000107 Reactome:R-HSA-5621481 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in IDA (PMID:9655483) UniProt PMID:9655483 NCBI chr19:35,904,403...35,908,295
Ensembl chr19:35,904,401...35,908,295 		JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIR2DS2 killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 involved_in IDA (PMID:9655483) UniProt PMID:9655483
G LOC124900573 killer cell immunoglobulin-like receptor 2DS2 involved_in IDA (PMID:9655483) UniProt PMID:9655483
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in IDA (PMID:9655483) UniProt PMID:9655483 NCBI chr19:35,904,403...35,908,295
Ensembl chr19:35,904,401...35,908,295 		JBrowse link
T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18305217) Ensembl
MGI		 PMID:18305217 GO_REF:0000107 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675 		JBrowse link
G ADA adenosine deaminase involved_in
acts_upstream_of		 IEA
ISO		 (PMID:11435465) Ensembl
MGI		 PMID:11435465 GO_REF:0000107 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G AL121845.2 novel transcript, LIME1-SLC2A4RG readthrough involved_in IEA InterPro GO_REF:0000002 Ensembl chr20:63,738,270...63,740,398 JBrowse link
G AL121845.3 novel protein, ZGPAT-LIME1 readthrough involved_in IEA InterPro GO_REF:0000002 Ensembl chr20:63,708,864...63,739,103 JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member involved_in NAS (PMID:9295052) UniProt PMID:9295052 NCBI chr16:75,228,181...75,268,007
Ensembl chr16:75,228,181...75,268,053 		JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IDA (PMID:15125833) UniProt PMID:15125833 NCBI chr 1:85,265,776...85,276,632
Ensembl chr 1:85,265,776...85,276,632 		JBrowse link
G BMX BMX non-receptor tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:15,500,807...15,556,519
Ensembl chr  X:15,464,246...15,556,529 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18228248) Ensembl
MGI		 PMID:18228248 GO_REF:0000107 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G BTK Bruton tyrosine kinase involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796 		JBrowse link
G BTN1A1 butyrophilin subfamily 1 member A1 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:26,500,303...26,510,425
Ensembl chr 6:26,500,303...26,510,425 		JBrowse link
G BTN2A1 butyrophilin subfamily 2 member A1 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:26,457,955...26,476,622
Ensembl chr 6:26,457,904...26,476,621 		JBrowse link
G BTN2A2 butyrophilin subfamily 2 member A2 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:26,383,108...26,394,874
Ensembl chr 6:26,383,096...26,394,874 		JBrowse link
G BTN2A3P butyrophilin subfamily 2 member A3, pseudogene involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:26,421,391...26,430,588
Ensembl chr 6:26,421,391...26,432,383
Ensembl chr 6:26,421,391...26,432,383 		JBrowse link
G BTN3A1 butyrophilin subfamily 3 member A1 involved_in IDA
IBA
IEA		 (PMID:21918970) UniProt
GO_Central
TreeGrafter		 PMID:21918970 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:26,402,275...26,415,208
Ensembl chr 6:26,402,237...26,415,208 		JBrowse link
G BTN3A2 butyrophilin subfamily 3 member A2 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:26,365,169...26,378,320
Ensembl chr 6:26,365,159...26,378,320 		JBrowse link
G BTN3A3 butyrophilin subfamily 3 member A3 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:26,440,504...26,453,415
Ensembl chr 6:26,440,472...26,453,415 		JBrowse link
G BTNL10P butyrophilin like 10, pseudogene involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:228,507,721...228,513,361
Ensembl chr 1:228,510,425...228,512,305 		JBrowse link
G BTNL2 butyrophilin like 2 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:32,393,339...32,407,181
Ensembl chr 6:32,393,339...32,407,181 		JBrowse link
G BTNL3 butyrophilin like 3 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:180,988,846...181,006,727
Ensembl chr 5:180,988,846...181,006,727 		JBrowse link
G BTNL8 butyrophilin like 8 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:180,899,159...180,950,906
Ensembl chr 5:180,899,077...180,950,906 		JBrowse link
G BTNL9 butyrophilin like 9 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:181,040,266...181,061,521
Ensembl chr 5:181,040,225...181,061,521 		JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17028169) Ensembl
MGI		 PMID:17028169 GO_REF:0000107 NCBI chr12:48,814,480...48,828,941
Ensembl chr12:48,813,794...48,828,941 		JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15637280), (PMID:17028169) Ensembl
MGI		 PMID:15637280 PMID:17028169 GO_REF:0000107 NCBI chr 2:151,832,771...152,099,167
Ensembl chr 2:151,832,771...152,099,167 		JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (PMID:23793062) MGI PMID:23793062 NCBI chr16:67,645,144...67,657,569
Ensembl chr16:67,644,988...67,657,569 		JBrowse link
G CBLB Cbl proto-oncogene B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12697763) Ensembl
MGI		 PMID:12697763 GO_REF:0000107 NCBI chr 3:105,655,461...105,869,449
Ensembl chr 3:105,655,461...105,869,552 		JBrowse link
G CD247 CD247 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
NAS		 (PMID:11435465)
(PMID:29789755), (PMID:30976362)		 Ensembl
MGI
TreeGrafter
GO_Central
ComplexPortal		 PMID:11435465 PMID:29789755 PMID:30976362 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:167,430,640...167,518,529
Ensembl chr 1:167,425,027...167,518,640 		JBrowse link
G CD276 CD276 molecule involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr15:73,683,944...73,714,514
Ensembl chr15:73,683,966...73,714,514 		JBrowse link
G CD28 CD28 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:23793062) Ensembl
MGI
GO_Central
TreeGrafter		 PMID:23793062 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,475...203,738,912 		JBrowse link
G CD2AP CD2 associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14512504) Ensembl
MGI		 PMID:14512504 GO_REF:0000107 NCBI chr 6:47,477,789...47,627,263
Ensembl chr 6:47,477,789...47,627,263 		JBrowse link
G CD3D CD3 delta subunit of T-cell receptor complex involved_in NAS (PMID:29789755) ComplexPortal PMID:29789755 NCBI chr11:118,338,954...118,342,705
Ensembl chr11:118,339,075...118,342,705 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex involved_in
acts_upstream_of_or_within		 IEA
ISO
NAS		 (PMID:10485657)
(PMID:29789755), (PMID:30976362)		 Ensembl
MGI
ComplexPortal		 PMID:10485657 PMID:29789755 PMID:30976362 GO_REF:0000107 NCBI chr11:118,304,730...118,316,173
Ensembl chr11:118,304,730...118,316,175 		JBrowse link
G CD3G CD3 gamma subunit of T-cell receptor complex involved_in NAS (PMID:29789755), (PMID:30976362) ComplexPortal PMID:29789755 PMID:30976362 NCBI chr11:118,344,344...118,355,161
Ensembl chr11:118,344,344...118,355,161 		JBrowse link
G CD8A CD8 subunit alpha involved_in IDA
ISS		 (PMID:17145893) ComplexPortal PMID:17145893 GO_REF:0000114 NCBI chr 2:86,784,605...86,808,396
Ensembl chr 2:86,784,610...86,808,396 		JBrowse link
G CD8B CD8 subunit beta involved_in IDA (PMID:17145893) ComplexPortal PMID:17145893 NCBI chr 2:86,815,369...86,861,886
Ensembl chr 2:86,815,339...86,861,924 		JBrowse link
G CLEC2A C-type lectin domain family 2 member A acts_upstream_of_or_within ISO (PMID:16143319) MGI PMID:16143319 NCBI chr12:9,877,742...9,932,370
Ensembl chr12:9,898,673...9,932,370 		JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18305217) Ensembl
MGI		 PMID:18305217 GO_REF:0000107 NCBI chr22:20,917,407...20,953,747
Ensembl chr22:20,917,407...20,953,747 		JBrowse link
G CSK C-terminal Src kinase involved_in TAS Reactome Reactome:R-HSA-202403 NCBI chr15:74,782,080...74,803,197
Ensembl chr15:74,782,080...74,803,197 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G DENND1B DENN domain containing 1B involved_in IEA
IBA
IMP		 (PMID:26774822) Ensembl
GO_Central
TreeGrafter
UniProt		 PMID:26774822 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:197,504,748...197,782,150
Ensembl chr 1:197,504,748...197,775,696 		JBrowse link
G EIF2B1 eukaryotic translation initiation factor 2B subunit alpha involved_in IDA (PMID:8626696) UniProt PMID:8626696 NCBI chr12:123,620,406...123,633,686
Ensembl chr12:123,620,406...123,633,766 		JBrowse link
G EIF2B2 eukaryotic translation initiation factor 2B subunit beta involved_in IDA (PMID:8626696) UniProt PMID:8626696 NCBI chr14:75,002,921...75,012,366
Ensembl chr14:75,002,921...75,012,366 		JBrowse link
G EIF2B3 eukaryotic translation initiation factor 2B subunit gamma involved_in IDA (PMID:8626696) UniProt PMID:8626696 NCBI chr 1:44,850,522...44,986,595
Ensembl chr 1:44,850,522...44,986,722 		JBrowse link
G EIF2B4 eukaryotic translation initiation factor 2B subunit delta involved_in IDA (PMID:8626696) UniProt PMID:8626696 NCBI chr 2:27,364,352...27,370,338
Ensembl chr 2:27,364,352...27,370,338 		JBrowse link
G EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon involved_in IDA (PMID:8626696) UniProt PMID:8626696 NCBI chr 3:184,135,358...184,145,311
Ensembl chr 3:184,135,038...184,146,127 		JBrowse link
G ERMAP erythroblast membrane associated protein (Scianna blood group) involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:42,817,122...42,844,991
Ensembl chr 1:42,817,122...42,844,991 		JBrowse link
G FCHO1 FCH and mu domain containing endocytic adaptor 1 involved_in IMP (PMID:32098969) UniProt PMID:32098969 NCBI chr19:17,747,744...17,788,561
Ensembl chr19:17,747,718...17,788,568 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:32610127) Ensembl
MGI		 PMID:32610127 GO_REF:0000107 NCBI chr 2:28,392,858...28,417,317
Ensembl chr 2:28,392,448...28,417,317 		JBrowse link
G FOXP3 forkhead box P3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10072494), (PMID:11265635) Ensembl
MGI		 PMID:10072494 PMID:11265635 GO_REF:0000107 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G FYB1 FYN binding protein 1 involved_in TAS
IBA
IEA		 (PMID:9207119) UniProt
GO_Central
TreeGrafter		 PMID:9207119 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:39,105,252...39,274,528
Ensembl chr 5:39,105,252...39,274,528 		JBrowse link
G FYB2 FYN binding protein 2 involved_in IMP
IEA
IBA		 (PMID:27335501) UniProt
TreeGrafter
GO_Central		 PMID:27335501 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:56,718,789...56,826,914
Ensembl chr 1:56,718,789...56,819,696 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in IDA
IEA
IBA		 (PMID:7722293) UniProt
TreeGrafter
GO_Central		 PMID:7722293 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452 		JBrowse link
G GATA3 GATA binding protein 3 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198 		JBrowse link
G HHLA2 HHLA2 member of B7 family involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:108,296,548...108,378,285
Ensembl chr 3:108,296,529...108,378,285 		JBrowse link
G HLA-A major histocompatibility complex, class I, A involved_in IDA (PMID:10435578) UniProt PMID:10435578 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572 		JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 involved_in IDA (PMID:32341563) UniProt PMID:32341563 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 involved_in IDA (PMID:32341563) UniProt PMID:32341563 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 involved_in IDA (PMID:32341563) UniProt PMID:32341563 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HLA-DRB3 major histocompatibility complex, class II, DR beta 3 involved_in IDA (PMID:32341563) UniProt PMID:32341563
G HRAS HRas proto-oncogene, GTPase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21444916) Ensembl
MGI		 PMID:21444916 GO_REF:0000107 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321 		JBrowse link
G ICOSLG inducible T cell costimulator ligand involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr21:44,216,981...44,240,943
Ensembl chr21:44,215,382...44,241,446 		JBrowse link
G ICOSLG inducible T cell costimulator ligand involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr21:5,022,531...5,046,683
Ensembl chr21:44,215,382...44,241,446 		JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (PMID:21444916) MGI PMID:21444916 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-202403 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in NAS (PMID:15125833) UniProt PMID:15125833 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,199...154,565,046 		JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D involved_in TAS Reactome Reactome:R-HSA-202403 NCBI chr 2:233,060,342...233,207,903
Ensembl chr 2:233,059,967...233,207,903 		JBrowse link
G ITK IL2 inducible T cell kinase involved_in IEA
IBA
ISS		 Ensembl
TreeGrafter
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:157,180,840...157,255,185
Ensembl chr 5:157,142,933...157,255,185 		JBrowse link
G KHDRBS1 KH RNA binding domain containing, signal transduction associated 1 involved_in IDA (PMID:9045636) UniProt PMID:9045636 NCBI chr 1:32,013,868...32,060,850
Ensembl chr 1:32,013,868...32,060,850 		JBrowse link
G LAT linker for activation of T cells involved_in IDA (PMID:25907557) UniProt PMID:25907557 NCBI chr16:28,984,803...28,990,784
Ensembl chr16:28,984,826...28,990,784 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-202403 NCBI chr 1:32,251,265...32,286,165
Ensembl chr 1:32,251,244...32,286,165 		JBrowse link
G LCP2 lymphocyte cytosolic protein 2 involved_in IDA (PMID:20551903) UniProt PMID:20551903 NCBI chr 5:170,246,233...170,297,777
Ensembl chr 5:170,246,233...170,297,815 		JBrowse link
G LIME1 Lck interacting transmembrane adaptor 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:63,735,701...63,739,103
Ensembl chr20:63,736,283...63,739,103 		JBrowse link
G MALT1 MALT1 paracaspase involved_in IEA
IBA
IDA		 (PMID:15125833) Ensembl
GO_Central
TreeGrafter
UniProt		 PMID:15125833 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr18:58,671,465...58,754,477
Ensembl chr18:58,671,465...58,754,477 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in NAS
TAS		 (PMID:15125833) UniProt
Reactome		 PMID:15125833 Reactome:R-HSA-202403 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9064344) Ensembl
MGI		 PMID:9064344 GO_REF:0000107 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MOG myelin oligodendrocyte glycoprotein involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:29,657,092...29,672,365
Ensembl chr 6:29,657,002...29,672,372 		JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISS UniProt GO_REF:0000024 NCBI chr19:35,887,952...35,902,303
Ensembl chr19:35,887,653...35,902,303 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase acts_upstream_of_or_within ISO (PMID:21444916) MGI PMID:21444916 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771 		JBrowse link
G PDE4B phosphodiesterase 4B involved_in IMP (PMID:17404263) BHF-UCL PMID:17404263 NCBI chr 1:65,792,510...66,374,579
Ensembl chr 1:65,792,514...66,374,579 		JBrowse link
G PDE4D phosphodiesterase 4D involved_in IMP (PMID:17404263) BHF-UCL PMID:17404263 NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha involved_in TAS Reactome Reactome:R-HSA-202403 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta involved_in TAS (PMID:20940048) UniProt PMID:20940048 NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114 		JBrowse link
G PLCG1 phospholipase C gamma 1 involved_in
acts_upstream_of_or_within		 TAS
ISO
IEA		 (PMID:15728238) Reactome
MGI
Ensembl		 PMID:15728238 GO_REF:0000107 Reactome:R-HSA-202403 NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:15728238) UniProt
MGI
Ensembl		 PMID:15728238 GO_REF:0000024 GO_REF:0000107 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685 		JBrowse link
G PRAM1 PML-RARA regulated adaptor molecule 1 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr19:8,490,056...8,502,640
Ensembl chr19:8,490,056...8,502,640 		JBrowse link
G PRKD2 protein kinase D2 involved_in IDA (PMID:17077180) BHF-UCL PMID:17077180 NCBI chr19:46,674,316...46,717,114
Ensembl chr19:46,674,275...46,717,127 		JBrowse link
G PSEN1 presenilin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17698590) Ensembl
MGI		 PMID:17698590 GO_REF:0000107 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691 		JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (PMID:17698590) MGI PMID:17698590 NCBI chr 1:226,870,616...226,903,668
Ensembl chr 1:226,870,184...226,927,726 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in
acts_upstream_of_or_within		 TAS
ISO
IEA
IBA		 (PMID:14752163) Reactome
MGI
TreeGrafter
GO_Central
Ensembl		 PMID:14752163 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 Reactome:R-HSA-202403 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:9064344) Ensembl
MGI		 PMID:9064344 GO_REF:0000107 NCBI chr12:6,946,577...6,961,316
Ensembl chr12:6,946,468...6,961,316 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in IEA
TAS
IDA		 (PMID:15557316)
(PMID:10358156)		 Ensembl
Reactome
UniProt
InterPro		 PMID:10358156 PMID:15557316 GO_REF:0000002 GO_REF:0000107 Reactome:R-HSA-202403 NCBI chr 1:198,638,713...198,757,476
Ensembl chr 1:198,638,457...198,757,476 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in TAS Reactome Reactome:R-HSA-202403 NCBI chr11:47,980,559...48,170,839
Ensembl chr11:47,980,425...48,170,839 		JBrowse link
G RBCK1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in IDA (PMID:20005846) UniProt PMID:20005846 NCBI chr20:408,299...432,139
Ensembl chr20:407,498...432,139 		JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:173,931,084...174,022,357
Ensembl chr 1:173,931,084...174,022,357 		JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:122,844,556...122,905,359
Ensembl chr 9:122,844,556...122,905,359 		JBrowse link
G RFTN1 raftlin, lipid raft linker 1 involved_in ISS
IEA		 CAFA
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:16,315,845...16,513,699
Ensembl chr 3:16,313,574...16,514,026 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
TAS
ISS		 (PMID:11894098) Ensembl
MGI
Reactome
UniProt		 PMID:11894098 GO_REF:0000024 GO_REF:0000107 Reactome:R-HSA-202403 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G RNF31 ring finger protein 31 involved_in IDA (PMID:20005846) UniProt PMID:20005846 NCBI chr14:24,146,875...24,160,655
Ensembl chr14:24,146,683...24,160,660 		JBrowse link
G SHB SH2 domain containing adaptor protein B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24645804) Ensembl
MGI		 PMID:24645804 GO_REF:0000107 NCBI chr 9:37,915,898...38,069,227
Ensembl chr 9:37,915,898...38,069,227 		JBrowse link
G SKAP1 src kinase associated phosphoprotein 1 involved_in IMP (PMID:11909961) UniProt PMID:11909961 NCBI chr17:48,133,442...48,445,061
Ensembl chr17:48,133,442...48,430,275 		JBrowse link
G SLC39A6 solute carrier family 39 member 6 involved_in IDA (PMID:34394081) UniProt PMID:34394081 NCBI chr18:36,108,531...36,129,340
Ensembl chr18:36,108,531...36,129,385 		JBrowse link
G SPN sialophorin involved_in ISO PMID:12496963 ARUK-UCL PMID:12496963 RGD:1358565 NCBI chr16:29,662,963...29,670,876
Ensembl chr16:29,662,979...29,670,876 		JBrowse link
G SPPL3 signal peptide peptidase like 3 involved_in IMP
ISS
IEA		 (PMID:25384971) UniProt
Ensembl		 PMID:25384971 GO_REF:0000024 GO_REF:0000107 NCBI chr12:120,762,510...120,904,358
Ensembl chr12:120,762,510...120,904,358 		JBrowse link
G STK11 serine/threonine kinase 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21487392) Ensembl
MGI		 PMID:21487392 GO_REF:0000107 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G STOML2 stomatin like 2 acts_upstream_of_or_within IMP (PMID:18641330) UniProt PMID:18641330 NCBI chr 9:35,099,776...35,103,195
Ensembl chr 9:35,099,776...35,103,195 		JBrowse link
G TEC tec protein tyrosine kinase involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:48,135,783...48,269,838
Ensembl chr 4:48,135,783...48,269,838 		JBrowse link
G THEMIS thymocyte selection associated involved_in ISS
IBA
IEA		 UniProt
GO_Central
TreeGrafter
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:127,696,628...127,918,595
Ensembl chr 6:127,708,072...127,918,631 		JBrowse link
G THEMIS2 thymocyte selection associated family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:22732588) Ensembl
MGI
TreeGrafter
GO_Central		 PMID:22732588 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:27,872,544...27,886,675
Ensembl chr 1:27,872,543...27,886,685 		JBrowse link
G THY1 Thy-1 cell surface antigen involved_in ISS
IEA		 UniProt
TreeGrafter		 GO_REF:0000024 GO_REF:0000118 NCBI chr11:119,415,476...119,424,985
Ensembl chr11:119,415,476...119,424,985 		JBrowse link
G TNFRSF21 TNF receptor superfamily member 21 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:47,231,532...47,309,905
Ensembl chr 6:47,231,532...47,309,905 		JBrowse link
G TRAC T cell receptor alpha constant involved_in NAS (PMID:29789755) ComplexPortal PMID:29789755 NCBI chr14:22,547,506...22,552,132
Ensembl chr14:22,547,506...22,552,156 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IMP
IDA
TAS		 (PMID:15125833)
(PMID:23514740)		 UniProt
Reactome		 PMID:15125833 PMID:23514740 Reactome:R-HSA-202403 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TRBC1 T cell receptor beta constant 1 involved_in NAS (PMID:29789755) ComplexPortal PMID:29789755 NCBI chr 7:142,791,694...142,793,141
Ensembl chr 7:142,791,694...142,793,368 		JBrowse link
G TRBC2 T cell receptor beta constant 2 involved_in NAS (PMID:29789755) ComplexPortal PMID:29789755 NCBI chr 7:142,801,041...142,802,529
Ensembl chr 7:142,801,041...142,802,748 		JBrowse link
G TRDC T cell receptor delta constant involved_in NAS (PMID:30976362) ComplexPortal PMID:30976362 NCBI chr14:22,462,932...22,466,577
Ensembl chr14:22,462,932...22,465,787 		JBrowse link
G TRGC1 T cell receptor gamma constant 1 involved_in NAS (PMID:30976362) ComplexPortal PMID:30976362 NCBI chr 7:38,260,088...38,265,678 JBrowse link
G TRGC2 T cell receptor gamma constant 2 involved_in NAS (PMID:30976362) ComplexPortal PMID:30976362 NCBI chr 7:38,240,024...38,249,572
Ensembl chr 7:38,239,580...38,249,572 		JBrowse link
G TXK TXK tyrosine kinase involved_in ISS
IEA
IBA		 UniProt
TreeGrafter
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:48,066,393...48,134,250
Ensembl chr 4:48,066,393...48,134,250 		JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N involved_in IMP (PMID:15125833) UniProt PMID:15125833 NCBI chr12:93,405,684...93,441,947
Ensembl chr12:93,405,673...93,441,947 		JBrowse link
G VTCN1 V-set domain containing T cell activation inhibitor 1 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:117,143,587...117,210,927
Ensembl chr 1:117,143,587...117,210,960 		JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 involved_in ISS
IEA		 (PMID:27400149) BHF-UCL
Ensembl		 PMID:27400149 GO_REF:0000107 NCBI chr12:752,579...911,452
Ensembl chr12:752,579...911,452 		JBrowse link
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 involved_in
acts_upstream_of_or_within		 TAS
ISO
IDA
IEA		 (PMID:20135127)
(PMID:9208839)
(PMID:9489702)		 Reactome
MGI
UniProt
Ensembl		 PMID:9208839 PMID:9489702 PMID:20135127 GO_REF:0000107 Reactome:R-HSA-202403 NCBI chr 2:97,713,576...97,756,364
Ensembl chr 2:97,713,576...97,739,862 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:37,474,580...37,484,377
Ensembl chr 1:37,474,580...37,484,377 		JBrowse link
G ZNF683 zinc finger protein 683 involved_in IDA (PMID:26179882) UniProt PMID:26179882 NCBI chr 1:26,361,634...26,374,518
Ensembl chr 1:26,361,634...26,374,522 		JBrowse link
TIRAP-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIRAP TIR domain containing adaptor protein involved_in IDA (PMID:11544529) BHF-UCL PMID:11544529 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in
acts_upstream_of_or_within		 IMP
ISO
IBA		 (PMID:10383454)
(PMID:10549626)		 BHF-UCL
MGI
GO_Central		 PMID:10383454 PMID:10549626 GO_REF:0000033 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G LGALS9 galectin 9 NOT|involved_in IDA (PMID:16116184) UniProt PMID:16116184 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15220916) Ensembl
MGI		 PMID:15220916 GO_REF:0000107 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:96,593,315...96,720,514
Ensembl chr10:96,593,315...96,720,514 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within IDA (PMID:11894098) MGI PMID:11894098 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G TLR2 toll like receptor 2 involved_in IDA (PMID:17128265) BHF-UCL PMID:17128265 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in ISS
IEA
IBA		 UniProt
TreeGrafter
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:2,741,648...2,756,336
Ensembl chr 4:2,741,648...2,756,342 		JBrowse link
toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in IDA
IEA
IBA		 (PMID:27986454) UniProt
TreeGrafter
GO_Central		 PMID:27986454 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex involved_in IDA (PMID:26189595) UniProt PMID:26189595 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G ECSIT ECSIT signaling integrator involved_in IDA (PMID:25371197) UniProt PMID:25371197 NCBI chr19:11,505,929...11,529,134
Ensembl chr19:11,505,929...11,529,172 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:10549626) GO_Central
MGI		 PMID:10549626 GO_REF:0000033 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 involved_in IDA (PMID:17878161) UniProt PMID:17878161 NCBI chr 3:10,164,919...10,243,745
Ensembl chr 3:10,164,919...10,243,745 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 involved_in IC (PMID:35977521) UniProt PMID:35977521 NCBI chr12:43,758,951...43,789,541
Ensembl chr12:43,758,944...43,798,307 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IDA (PMID:25636800) UniProt PMID:25636800 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G LGALS9 galectin 9 NOT|involved_in IDA (PMID:16116184) UniProt PMID:16116184 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G LY96 lymphocyte antigen 96 involved_in ISS
IBA
IEA		 UniProt
GO_Central
TreeGrafter
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:73,991,392...74,099,857
Ensembl chr 8:73,991,392...74,029,079 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in IDA (PMID:25371197) UniProt PMID:25371197 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IDA
IBA
IEA		 (PMID:16751103) UniProt
GO_Central
TreeGrafter		 PMID:16751103 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29624734) Ensembl
MGI		 PMID:29624734 GO_REF:0000107 NCBI chr17:42,536,241...42,544,449
Ensembl chr17:42,536,241...42,544,449 		JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 (PMID:18261938)
(PMID:7479976)		 Ensembl
MGI
GO_Central
TreeGrafter
UniProt		 PMID:7479976 PMID:18261938 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NMI N-myc and STAT interactor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:151,270,470...151,289,668
Ensembl chr 2:151,270,470...151,289,894 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IMP (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chr12:112,906,962...112,933,219
Ensembl chr12:112,905,856...112,933,219 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:96,593,315...96,720,514
Ensembl chr10:96,593,315...96,720,514 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IDA (PMID:25355951) UniProt PMID:25355951 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894098) Ensembl
MGI		 PMID:11894098 GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G S100A14 S100 calcium binding protein A14 involved_in IDA
IEA
IBA		 (PMID:17625598) UniProt
TreeGrafter
GO_Central		 PMID:17625598 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:153,614,255...153,616,325
Ensembl chr 1:153,614,255...153,616,986 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:5,208,920...5,234,860
Ensembl chr17:5,208,920...5,234,860 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IDA (PMID:28747347) UniProt PMID:28747347 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IDA (PMID:12471095) UniProt PMID:12471095 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IDA (PMID:28630139) UniProt PMID:28630139 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IDA
IBA
IEA		 (PMID:16751103) UniProt
GO_Central
TreeGrafter		 PMID:16751103 GO_REF:0000033 GO_REF:0000118 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 (PMID:25549946)
(PMID:10196138), (PMID:15618008), (PMID:18222170)		 Ensembl
MGI
GO_Central
TreeGrafter
UniProt		 PMID:10196138 PMID:15618008 PMID:18222170 PMID:25549946 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TMED7-TICAM2 TMED7-TICAM2 readthrough involved_in IDA (PMID:28630139) UniProt PMID:28630139 NCBI chr 5:115,578,496...115,626,036
Ensembl chr 5:115,578,642...115,626,161 		JBrowse link
G TMEM126A transmembrane protein 126A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25549946) Ensembl
MGI		 PMID:25549946 GO_REF:0000107 NCBI chr11:85,647,967...85,656,542
Ensembl chr11:85,647,967...85,656,547 		JBrowse link
G TNIP3 TNFAIP3 interacting protein 3 involved_in IDA (PMID:17088249) UniProt PMID:17088249 NCBI chr 4:121,131,408...121,227,483
Ensembl chr 4:121,131,408...121,227,466 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IDA (PMID:18222170) UniProt PMID:18222170 NCBI chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IDA (PMID:25371197) UniProt PMID:25371197 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TRIL TLR4 interactor with leucine rich repeats involved_in IDA
IBA
IEA		 (PMID:19710467) UniProt
GO_Central
TreeGrafter		 PMID:19710467 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:28,953,358...28,958,330
Ensembl chr 7:28,953,358...28,958,330 		JBrowse link
toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIRAP TIR domain containing adaptor protein NOT|involved_in ISO (MGI:3531416|PMID:12447442) BHF-UCL PMID:12447442 MGI:3531416 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR5 toll like receptor 5 involved_in IDA (PMID:17128265) BHF-UCL PMID:17128265 NCBI chr 1:223,109,404...223,143,248
Ensembl chr 1:223,109,404...223,143,248 		JBrowse link
TRAM-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCE protein kinase C epsilon involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990 		JBrowse link
G RAB11FIP2 RAB11 family interacting protein 2 involved_in IDA (PMID:30883606) UniProt PMID:30883606 NCBI chr10:118,004,916...118,046,941
Ensembl chr10:118,004,916...118,046,941 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IDA
IMP		 (PMID:19412184)
(PMID:22685567)		 UniProt PMID:19412184 PMID:22685567 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TMED7-TICAM2 TMED7-TICAM2 readthrough involved_in IMP
IDA		 (PMID:22685567)
(PMID:19412184)		 UniProt PMID:19412184 PMID:22685567 NCBI chr 5:115,578,496...115,626,036
Ensembl chr 5:115,578,642...115,626,161 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19770
    cellular process 18460
      signal transduction 6605
        cell surface receptor signaling pathway 3226
          immune response-regulating cell surface receptor signaling pathway 388
            Fc receptor signaling pathway + 60
            immune response-activating cell surface receptor signaling pathway + 356
            immune response-inhibiting cell surface receptor signaling pathway + 9
            immune response-regulating cell surface receptor signaling pathway involved in phagocytosis + 23
Path 2
Term Annotations click to browse term
  biological_process 19770
    biological regulation 13405
      regulation of biological process 13030
        regulation of cellular process 12502
          signal transduction 6605
            immune response-regulating signaling pathway 576
              immune response-regulating cell surface receptor signaling pathway 388
                Fc receptor signaling pathway + 60
                immune response-activating cell surface receptor signaling pathway + 356
                immune response-inhibiting cell surface receptor signaling pathway + 9
                immune response-regulating cell surface receptor signaling pathway involved in phagocytosis + 23
paths to the root