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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of myeloid leukocyte differentiation
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Accession:GO:0002763 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.
Synonyms:exact_synonym: up regulation of myeloid leukocyte differentiation;   upregulation of myeloid leukocyte differentiation
 narrow_synonym: activation of myeloid leukocyte differentiation;   stimulation of myeloid leukocyte differentiation


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positive regulation of myeloid leukocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd101 CD101 molecule acts_upstream_of_or_within ISO (MGI:5287956|PMID:21613616) MGI PMID:21613616 MGI:5287956 NCBI chrNW_004936627:2,121,312...2,154,880 JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (MGI:49671|PMID:1375116), (MGI:63529|PMID:7690439) MGI PMID:1375116 PMID:7690439 MGI:49671 MGI:63529 NCBI chrNW_004936647:3,102,922...3,104,758 JBrowse link
G Kitlg KIT ligand acts_upstream_of_or_within ISO (MGI:49671|PMID:1375116), (MGI:63529|PMID:7690439) MGI PMID:1375116 PMID:7690439 MGI:49671 MGI:63529 NCBI chrNW_004936507:5,566,144...5,650,412 JBrowse link
positive regulation of eosinophil differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il5 interleukin 5 ISO RGD PMID:10529595 PMID:10727846 RGD:2303509 RGD:2303750 NCBI chrNW_004936647:2,647,982...2,651,477 JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in ISO (MGI:5488531|PMID:23515163) CACAO PMID:23515163 MGI:5488531 NCBI chrNW_004936470:22,401,713...22,408,808 JBrowse link
positive regulation of granulocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Evi2b ecotropic viral integration site 2B involved_in ISO (PMID:28186500) UniProt PMID:28186500 NCBI chrNW_004936538:3,454,956...3,464,878 JBrowse link
G Gfi1b growth factor independent 1B transcriptional repressor involved_in ISO (MGI:5284774|PMID:17707228) UniProt PMID:17707228 MGI:5284774 NCBI chrNW_004936487:19,414,135...19,417,465 JBrowse link
G Hax1 HCLS1 associated protein X-1 involved_in ISO (PMID:23001182) BHF-UCL PMID:23001182 NCBI chrNW_004936580:3,961,433...3,964,322 JBrowse link
G Hcls1 hematopoietic cell-specific Lyn substrate 1 involved_in ISO (PMID:23001182)
(MGI:5448611|PMID:23001182)
BHF-UCL PMID:23001182 MGI:5448611 NCBI chrNW_004936536:8,065,489...8,084,777 JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in ISO (PMID:19620402)
(PMID:23001182)
UniProt
BHF-UCL
PMID:19620402 PMID:23001182 NCBI chrNW_004936818:453,635...569,194 JBrowse link
G Tesc tescalcin involved_in ISO (PMID:20060826) UniProt PMID:20060826 NCBI chrNW_004936558:5,397,018...5,417,335 JBrowse link
positive regulation of macrophage differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin related polypeptide alpha involved_in ISO (PMID:10822112) UniProt PMID:10822112 NCBI chrNW_004936528:3,800,801...3,806,000 JBrowse link
G Casp8 caspase 8 involved_in ISO (PMID:17047155) UniProt PMID:17047155 NCBI chrNW_004936726:554,627...596,334 JBrowse link
G Csf1 colony stimulating factor 1 involved_in
acts_upstream_of_or_within
ISO (PMID:2460758)
(MGI:893319|PMID:9215625)
BHF-UCL
MGI
PMID:2460758 PMID:9215625 MGI:893319 NCBI chrNW_004936704:1,372,137...1,393,355 JBrowse link
G Fadd Fas associated via death domain involved_in ISO (PMID:17047155) UniProt PMID:17047155 NCBI chrNW_004936599:633,501...639,412 JBrowse link
G Hcls1 hematopoietic cell-specific Lyn substrate 1 involved_in ISO (MGI:5448611|PMID:23001182) BHF-UCL PMID:23001182 MGI:5448611 NCBI chrNW_004936536:8,065,489...8,084,777 JBrowse link
G Hsf1 heat shock transcription factor 1 involved_in ISO (PMID:24504023) ARUK-UCL PMID:24504023 NCBI chrNW_004936470:7,927,734...7,950,805 JBrowse link
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO (MGI:3525032|PMID:15616565) MGI PMID:15616565 MGI:3525032 NCBI chrNW_004936532:5,236,175...5,238,689 JBrowse link
G Il34 interleukin 34 involved_in ISO (PMID:23409120) CACAO PMID:23409120 NCBI chrNW_004936475:22,967,962...22,979,954 JBrowse link
G Lif LIF interleukin 6 family cytokine acts_upstream_of_or_within ISO (PMID:7957045) MGI PMID:7957045 NCBI chrNW_004936904:410,043...413,256 JBrowse link
G Prkca protein kinase C alpha involved_in ISO (MGI:5306334|PMID:9508782) UniProt PMID:9508782 MGI:5306334 NCBI chrNW_004936541:6,231,604...6,488,201 JBrowse link
G Rb1 RB transcriptional corepressor 1 acts_upstream_of_or_within ISO (MGI:3525032|PMID:15616565) MGI PMID:15616565 MGI:3525032 NCBI chrNW_004936565:1,596,227...1,746,706 JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:17047155) UniProt PMID:17047155 NCBI chrNW_004936534:9,326,307...9,361,943 JBrowse link
G Ror2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:25749876 RGD:11537353 NCBI chrNW_004936796:630,307...675,157 JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in ISO (MGI:5488531|PMID:23515163) CACAO PMID:23515163 MGI:5488531 NCBI chrNW_004936470:22,401,713...22,408,808 JBrowse link
positive regulation of mast cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgam integrin subunit alpha M involved_in ISO (MGI:1328479|PMID:9862668) UniProt PMID:9862668 MGI:1328479 NCBI chrNW_004936543:8,460,526...8,508,524 JBrowse link
G Pla2g3 phospholipase A2 group III involved_in ISO (MGI:5492190|PMID:23624557) UniProt PMID:23624557 MGI:5492190 NCBI chrNW_004936755:307,166...312,683 JBrowse link
positive regulation of microglia differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor beta 1 involved_in ISO (MGI:6192878|PMID:29909984) UniProt PMID:29909984 MGI:6192878 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
positive regulation of monocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acin1 apoptotic chromatin condensation inducer 1 involved_in ISO (PMID:12393560) UniProt PMID:12393560 NCBI chrNW_004936722:1,252,083...1,264,018 JBrowse link
G Cd4 CD4 molecule involved_in ISO (PMID:24942581) CAFA PMID:24942581 NCBI chrNW_004936709:997,776...1,022,791 JBrowse link
G Cd74 CD74 molecule involved_in ISO (PMID:24942581) CAFA PMID:24942581 NCBI chrNW_004936504:4,522,576...4,532,289 JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within ISO (MGI:893319|PMID:9215625) MGI PMID:9215625 MGI:893319 NCBI chrNW_004936704:1,372,137...1,393,355 JBrowse link
G Fes FES proto-oncogene, tyrosine kinase involved_in ISO (PMID:28389358) ARUK-UCL PMID:28389358 NCBI chrNW_004936483:16,123,938...16,135,044 JBrowse link
G Il34 interleukin 34 involved_in ISO (PMID:23409120) CACAO PMID:23409120 NCBI chrNW_004936475:22,967,962...22,979,954 JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO murine WEHI-3B D+ cells with or without retinoic acid RGD PMID:7947389 RGD:2291846 NCBI chrNW_004936522:3,034,364...3,037,632 JBrowse link
G LOC101960808 dendrocyte expressed seven transmembrane protein involved_in ISO (MGI:5319610|PMID:17713547) UniProt PMID:17713547 MGI:5319610 NCBI chrNW_004936470:39,664,573...39,671,532 JBrowse link
G Zfp36l1 ZFP36 ring finger protein like 1 involved_in ISO (PMID:26542173) UniProt PMID:26542173 NCBI chrNW_004936495:12,045,679...12,050,737 JBrowse link
positive regulation of neutrophil differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (MGI:2654310|PMID:12406904) MGI PMID:12406904 MGI:2654310 NCBI chrNW_004936686:1,459,582...1,556,478 JBrowse link
positive regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr68 G protein-coupled receptor 68 acts_upstream_of_or_within ISO (MGI:3848292|PMID:19479052) MGI PMID:19479052 MGI:3848292 NCBI chrNW_004936488:18,257,765...18,278,530 JBrowse link
G LOC101962495 transmembrane immune signaling adaptor TYROBP involved_in ISO (MGI:3653295|PMID:14969392) UniProt PMID:14969392 MGI:3653295 NCBI chrNW_004936570:457,993...460,735 JBrowse link
G Ninj1 ninjurin 1 involved_in ISO (MGI:6458683|PMID:30700695) UniProt PMID:30700695 MGI:6458683 NCBI chrNW_004936487:2,486,831...2,531,943 JBrowse link
G Slc9b2 solute carrier family 9 member B2 acts_upstream_of_or_within ISO (MGI:3785147|PMID:18269914) MGI PMID:18269914 MGI:3785147 NCBI chrNW_004936520:316,070...371,590 JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within ISO (MGI:3785147|PMID:18269914), (MGI:5489769|PMID:22437732), (MGI:5522615|PMID:23980096) MGI PMID:18269914 PMID:22437732 PMID:23980096 MGI:3785147 MGI:5489769 MGI:5522615 NCBI chrNW_004936747:1,255,803...1,288,252 JBrowse link
positive regulation of osteoclast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asxl2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO (MGI:5514358|PMID:21490954) MGI PMID:21490954 MGI:5514358 NCBI chrNW_004936493:6,463,771...6,602,244 JBrowse link
G Ca2 carbonic anhydrase 2 ISO RGD PMID:10523502 RGD:1600711 NCBI chrNW_004936544:362,591...379,151 JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO RGD PMID:9920817 RGD:2303108 NCBI chrNW_004936490:253,279...259,947 JBrowse link
G Creb1 cAMP responsive element binding protein 1 acts_upstream_of_or_within ISO (MGI:5495340|PMID:23395171) MGI PMID:23395171 MGI:5495340 NCBI chrNW_004936631:3,721,307...3,785,346 JBrowse link
G Csf1 colony stimulating factor 1 involved_in
acts_upstream_of_or_within
ISO (PMID:15304486)
(MGI:3528531|PMID:15657444)
(MGI:3689489|PMID:17053831), (MGI:4849322|PMID:21048959)
(MGI:893319|PMID:9215625)
BHF-UCL
MGI
PMID:9215625 PMID:15304486 PMID:15657444 PMID:17053831 PMID:21048959 MGI:3528531 MGI:3689489 MGI:4849322 MGI:893319 NCBI chrNW_004936704:1,372,137...1,393,355 JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO RGD PMID:17121910 RGD:2293713 NCBI chrNW_004936504:4,898,947...4,927,195 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (MGI:5495340|PMID:23395171) MGI PMID:23395171 MGI:5495340 NCBI chrNW_004936488:4,384,710...4,388,118 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO RGD PMID:28731198 RGD:13792731 NCBI chrNW_004936536:6,730,070...6,893,818 JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:16220542) BHF-UCL PMID:16220542 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:17888176) BHF-UCL PMID:17888176 NCBI chrNW_004936515:4,056,214...4,066,121 JBrowse link
G Il17a interleukin 17A involved_in ISO (PMID:17888176) BHF-UCL PMID:17888176 NCBI chrNW_004936476:8,621,860...8,625,008 JBrowse link
G Il20 interleukin 20 acts_upstream_of_or_within ISO (MGI:5296273|PMID:21844205) MGI PMID:21844205 MGI:5296273 NCBI chrNW_004936557:5,749,419...5,751,776 JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:17888176) BHF-UCL PMID:17888176 NCBI chrNW_004936646:743,630...745,998 JBrowse link
G Klf10 Kruppel like factor 10 acts_upstream_of_or_within ISO (MGI:3528531|PMID:15657444) MGI PMID:15657444 MGI:3528531 NCBI chrNW_004936470:40,980,487...40,986,880 JBrowse link
G LOC101955781 osteoclast stimulatory transmembrane protein involved_in ISO (MGI:5319606|PMID:18064667) UniProt PMID:18064667 MGI:5319606 NCBI chrNW_004936514:6,601,580...6,608,785 JBrowse link
G LOC101964209 C-C chemokine receptor type 1 involved_in ISO (PMID:21403648) UniProt PMID:21403648 NCBI chrNW_004936596:177,774...183,186 JBrowse link
G LOC101965998 notch receptor 2 involved_in ISO (MGI:3814108|PMID:18710934) UniProt PMID:18710934 MGI:3814108 NCBI chrNW_004936872:454,273...539,544 JBrowse link
G LOC101971027 neuroendocrine secretory protein 55 acts_upstream_of_or_within ISO (MGI:3619837|PMID:15797856) MGI PMID:15797856 MGI:3619837 NCBI chrNW_004936530:1,353,432...1,407,437 JBrowse link
G Pou4f1 POU class 4 homeobox 1 involved_in ISO (MGI:5825429|PMID:17668438) UniProt PMID:17668438 MGI:5825429 NCBI chrNW_004936511:2,857,017...2,859,705 JBrowse link
G Pou4f2 POU class 4 homeobox 2 involved_in ISO (MGI:5825429|PMID:17668438) UniProt PMID:17668438 MGI:5825429 NCBI chrNW_004936535:2,705,184...2,711,785 JBrowse link
G Ppargc1b PPARG coactivator 1 beta involved_in ISO (MGI:3838421|PMID:19252502) DFLAT PMID:19252502 MGI:3838421 NCBI chrNW_004936504:5,099,334...5,198,279 JBrowse link
G Tmem64 transmembrane protein 64 acts_upstream_of_or_within ISO (MGI:5495340|PMID:23395171) MGI PMID:23395171 MGI:5495340 NCBI chrNW_004936544:4,326,083...4,347,809 JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:17888176) BHF-UCL PMID:17888176 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in
ISO (MGI:5295788|PMID:21982707)
(MGI:3528531|PMID:15657444), (MGI:3575849|PMID:15724149)
(PMID:15304486), (PMID:17241109), (PMID:19560569)
(MGI:3689489|PMID:17053831), (MGI:4849322|PMID:21048959)
RGD
MGI
UniProt
PMID:11092398 PMID:15304486 PMID:15657444 PMID:15724149 PMID:17053831 More... MGI:3528531 MGI:3575849 MGI:3689489 MGI:4849322 MGI:5295788 RGD:730134 NCBI chrNW_004936747:1,255,803...1,288,252 JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:17135271) UniProt PMID:17135271 NCBI chrNW_004936533:1,857,685...1,874,973 JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6294223|PMID:16418779) UniProt PMID:16418779 MGI:6294223 NCBI chrNW_004936476:18,659,725...18,665,406 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12295
    cellular process 11513
      positive regulation of cellular process 5194
        positive regulation of cell differentiation 913
          positive regulation of myeloid cell differentiation 108
            positive regulation of myeloid leukocyte differentiation 63
              positive regulation of granulocyte differentiation + 9
              positive regulation of macrophage differentiation + 15
              positive regulation of mast cell differentiation 2
              positive regulation of monocyte differentiation 9
              positive regulation of osteoclast differentiation + 30
Path 2
Term Annotations click to browse term
  biological_process 12295
    developmental process 5793
      anatomical structure development 5417
        multicellular organism development 4956
          system development 4647
            immune system development 971
              hematopoietic or lymphoid organ development 909
                hemopoiesis 862
                  leukocyte differentiation 538
                    myeloid leukocyte differentiation 217
                      regulation of myeloid leukocyte differentiation 118
                        positive regulation of myeloid leukocyte differentiation 63
                          positive regulation of granulocyte differentiation + 9
                          positive regulation of macrophage differentiation + 15
                          positive regulation of mast cell differentiation 2
                          positive regulation of monocyte differentiation 9
                          positive regulation of osteoclast differentiation + 30
paths to the root