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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of myeloid leukocyte differentiation
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Accession:GO:0002763 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.
Synonyms:exact_synonym: up regulation of myeloid leukocyte differentiation;   upregulation of myeloid leukocyte differentiation
 narrow_synonym: activation of myeloid leukocyte differentiation;   stimulation of myeloid leukocyte differentiation



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positive regulation of myeloid leukocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD101 CD101 molecule acts_upstream_of_or_within ISO (MGI:5287956|PMID:21613616) MGI PMID:21613616 MGI:5287956 NCBI chr17:54,391,572...54,427,350
Ensembl chr17:54,392,165...54,425,620
JBrowse link
G IL3 interleukin 3 acts_upstream_of_or_within ISO (MGI:49671|PMID:1375116), (MGI:63529|PMID:7690439) MGI PMID:1375116 PMID:7690439 MGI:49671 MGI:63529 NCBI chr11:20,330,480...20,332,668
Ensembl chr11:20,330,480...20,332,668
JBrowse link
G KITLG KIT ligand acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:49671|PMID:1375116), (MGI:63529|PMID:7690439) MGI
Ensembl
PMID:1375116 PMID:7690439 GO_REF:0000107 MGI:49671 MGI:63529 NCBI chr15:29,591,068...29,671,985
Ensembl chr15:29,591,170...29,671,974
JBrowse link
positive regulation of eosinophil differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL5 interleukin 5 ISO RGD PMID:10529595 PMID:10727846 RGD:2303509 RGD:2303750 NCBI chr11:20,825,469...20,827,269
Ensembl chr11:20,825,469...20,827,269
JBrowse link
G TRIB1 tribbles pseudokinase 1 involved_in ISO (MGI:5488531|PMID:23515163) CACAO PMID:23515163 MGI:5488531 NCBI chr13:23,337,788...23,346,304
Ensembl chr13:23,337,788...23,346,304
JBrowse link
positive regulation of granulocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EVI2B ecotropic viral integration site 2B involved_in ISO (PMID:28186500) UniProt PMID:28186500 NCBI chr 9:41,526,232...41,538,453
Ensembl chr 9:41,535,738...41,537,108
JBrowse link
G GFI1B growth factor independent 1B transcriptional repressor involved_in ISO (MGI:5284774|PMID:17707228) UniProt PMID:17707228 MGI:5284774 NCBI chr 9:51,380,697...51,394,679
Ensembl chr 9:51,380,696...51,392,812
JBrowse link
G HAX1 HCLS1 associated protein X-1 involved_in ISO (PMID:23001182) BHF-UCL PMID:23001182 NCBI chr 7:42,969,711...42,972,783
Ensembl chr 7:42,969,713...42,972,710
JBrowse link
G HCLS1 hematopoietic cell-specific Lyn substrate 1 involved_in ISO (PMID:23001182)
(MGI:5448611|PMID:23001182)
BHF-UCL PMID:23001182 MGI:5448611 NCBI chr33:24,901,023...24,925,710
Ensembl chr33:24,901,287...24,922,923
JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in ISO (PMID:23001182)
(PMID:19620402)
BHF-UCL
UniProt
PMID:19620402 PMID:23001182 NCBI chr32:28,516,002...28,633,759
Ensembl chr32:28,517,108...28,634,019
JBrowse link
G MIR223 microRNA mir-223 acts_upstream_of_or_within ISO (MGI:3811177|PMID:18278031) MGI PMID:18278031 MGI:3811177 NCBI chr  X:50,838,131...50,838,233
Ensembl chr  X:50,838,131...50,838,233
JBrowse link
G RUNX1 RUNX family transcription factor 1 involved_in ISO (PMID:9199349) UniProt PMID:9199349 NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839
JBrowse link
G TESC tescalcin involved_in ISO (PMID:20060826) UniProt PMID:20060826 NCBI chr26:13,645,513...13,700,521
Ensembl chr26:13,645,511...13,689,367
JBrowse link
positive regulation of macrophage differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP8 caspase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:10,362,071...10,402,108
Ensembl chr37:10,391,048...10,401,822
JBrowse link
G CRSP-3 calcitonin receptor-stimulating peptide 3 involved_in ISO (PMID:10822112) UniProt PMID:10822112 NCBI chr21:37,676,841...37,680,643
Ensembl chr21:37,676,841...37,680,645
JBrowse link
G CSF1 colony stimulating factor 1 acts_upstream_of_or_within
involved_in
ISO (MGI:893319|PMID:9215625)
(PMID:2460758)
MGI
BHF-UCL
PMID:2460758 PMID:9215625 MGI:893319 NCBI chr 6:42,028,454...42,047,028
Ensembl chr 6:42,034,149...42,049,371
JBrowse link
G FADD Fas associated via death domain involved_in ISO (PMID:17047155) UniProt PMID:17047155 NCBI chr18:48,087,447...48,094,497 JBrowse link
G HCLS1 hematopoietic cell-specific Lyn substrate 1 involved_in ISO (MGI:5448611|PMID:23001182) BHF-UCL PMID:23001182 MGI:5448611 NCBI chr33:24,901,023...24,925,710
Ensembl chr33:24,901,287...24,922,923
JBrowse link
G HSF1 heat shock transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:37,724,741...37,745,259
Ensembl chr13:37,724,759...37,745,252
JBrowse link
G IL34 interleukin 34 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:76,601,310...76,612,665
Ensembl chr 5:76,555,214...76,625,012
JBrowse link
G LIF LIF interleukin 6 family cytokine acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:7957045) MGI
Ensembl
PMID:7957045 GO_REF:0000107 NCBI chr26:23,400,226...23,418,538
Ensembl chr26:23,403,364...23,406,851
JBrowse link
G LOC102151783 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO (MGI:3525032|PMID:15616565) MGI PMID:15616565 MGI:3525032 NCBI chr10:54,954,852...54,957,116 JBrowse link
G PRKCA protein kinase C alpha involved_in ISO (MGI:5306334|PMID:9508782) UniProt PMID:9508782 MGI:5306334 NCBI chr 9:13,638,106...13,879,571
Ensembl chr 9:13,644,010...13,967,630
JBrowse link
G RB1 RB transcriptional corepressor 1 acts_upstream_of_or_within ISO (MGI:3525032|PMID:15616565) MGI PMID:15616565 MGI:3525032 NCBI chr22:3,061,621...3,204,625
Ensembl chr22:3,063,239...3,257,726
JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:17047155) UniProt PMID:17047155 NCBI chr35:3,367,796...3,407,631
Ensembl chr35:3,263,226...3,405,883
JBrowse link
G ROR2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:25749876 RGD:11537353 NCBI chr 1:95,209,122...95,280,956
Ensembl chr 1:95,088,745...95,280,151
JBrowse link
G TRIB1 tribbles pseudokinase 1 involved_in ISO (MGI:5488531|PMID:23515163) CACAO PMID:23515163 MGI:5488531 NCBI chr13:23,337,788...23,346,304
Ensembl chr13:23,337,788...23,346,304
JBrowse link
positive regulation of mast cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGAM integrin subunit alpha M involved_in ISO (MGI:1328479|PMID:9862668) UniProt PMID:9862668 MGI:1328479 NCBI chr 6:16,944,062...16,996,525
Ensembl chr 6:16,808,971...16,996,286
JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:24,127,074...24,132,508
Ensembl chr26:24,128,005...24,132,508
JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO (MGI:3605581|PMID:15947484) MGI PMID:15947484 MGI:3605581 NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103
JBrowse link
positive regulation of microglia differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B9D2 B9 domain containing 2 involved_in ISO (MGI:6192878|PMID:29909984) UniProt PMID:29909984 MGI:6192878 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
positive regulation of monocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACIN1 apoptotic chromatin condensation inducer 1 involved_in ISO (PMID:12393560) UniProt PMID:12393560 NCBI chr 8:3,370,469...3,405,710
Ensembl chr 8:3,371,004...3,405,682
JBrowse link
G CD4 CD4 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,204,003...38,250,771
Ensembl chr27:38,204,003...38,250,771
JBrowse link
G CD74 CD74 molecule involved_in ISO (PMID:24942581) CAFA PMID:24942581 NCBI chr 4:58,689,745...58,698,421
Ensembl chr 4:58,689,752...58,698,151
JBrowse link
G CSF1 colony stimulating factor 1 acts_upstream_of_or_within ISO (MGI:893319|PMID:9215625) MGI PMID:9215625 MGI:893319 NCBI chr 6:42,028,454...42,047,028
Ensembl chr 6:42,034,149...42,049,371
JBrowse link
G DCSTAMP dendrocyte expressed seven transmembrane protein involved_in ISO (MGI:5319610|PMID:17713547) UniProt PMID:17713547 MGI:5319610 NCBI chr13:5,542,474...5,559,433
Ensembl chr13:5,542,425...5,571,968
JBrowse link
G FES FES proto-oncogene, tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,346,975...53,356,547
Ensembl chr 3:53,347,012...53,356,516
JBrowse link
G HLA-DRB1 MHC class II DLA DRB1 beta chain involved_in ISO (PMID:24942581) CAFA PMID:24942581 NCBI chr12:2,151,409...2,164,564 JBrowse link
G IL34 interleukin 34 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:76,601,310...76,612,665
Ensembl chr 5:76,555,214...76,625,012
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO murine WEHI-3B D+ cells with or without retinoic acid RGD PMID:7947389 RGD:2291846 NCBI chr 5:50,966,698...50,968,939 JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:42,663,287...42,668,665
Ensembl chr 8:42,664,223...42,668,514
JBrowse link
positive regulation of neutrophil differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EVI2B ecotropic viral integration site 2B involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:41,526,232...41,538,453
Ensembl chr 9:41,535,738...41,537,108
JBrowse link
G IKZF1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (MGI:2654310|PMID:12406904) MGI PMID:12406904 MGI:2654310 NCBI chr18:1,661,851...1,750,987
Ensembl chr18:1,661,690...1,770,768
JBrowse link
positive regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPR68 G protein-coupled receptor 68 acts_upstream_of_or_within ISO (MGI:3848292|PMID:19479052) MGI PMID:19479052 MGI:3848292 NCBI chr 8:62,090,050...62,108,922
Ensembl chr 8:62,092,135...62,093,217
JBrowse link
G NINJ1 ninjurin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:98,566,520...98,576,668
Ensembl chr 1:98,567,680...98,576,657
JBrowse link
G SLC9B2 solute carrier family 9 member B2 acts_upstream_of_or_within ISO (MGI:3785147|PMID:18269914) MGI PMID:18269914 MGI:3785147 NCBI chr32:24,354,741...24,419,198
Ensembl chr32:24,360,050...24,417,372
JBrowse link
G TNFSF11 TNF superfamily member 11 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3785147|PMID:18269914), (MGI:5489769|PMID:22437732), (MGI:5522615|PMID:23980096) Ensembl
MGI
PMID:18269914 PMID:22437732 PMID:23980096 GO_REF:0000107 MGI:3785147 MGI:5489769 MGI:5522615 NCBI chr22:8,226,931...8,257,926
Ensembl chr22:8,227,555...8,258,645
JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:116,757,271...116,760,453
Ensembl chr 1:116,757,289...116,772,325
JBrowse link
positive regulation of osteoclast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASXL2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO (MGI:5514358|PMID:21490954) MGI PMID:21490954 MGI:5514358 NCBI chr17:19,914,026...20,065,141
Ensembl chr17:19,895,568...20,044,691
JBrowse link
G CA2 carbonic anhydrase 2 ISO RGD PMID:10523502 RGD:1600711 NCBI chr29:31,959,225...31,975,309
Ensembl chr29:31,935,172...31,980,579
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO RGD PMID:9920817 RGD:2303108 NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852
JBrowse link
G CCR1 chemokine (C-C motif) receptor 1 involved_in ISO (PMID:21403648) UniProt PMID:21403648 NCBI chr20:42,421,356...42,427,177
Ensembl chr20:42,421,356...42,426,958
JBrowse link
G CREB1 cAMP responsive element binding protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5495340|PMID:23395171) Ensembl
MGI
PMID:23395171 GO_REF:0000107 MGI:5495340 NCBI chr37:15,921,214...15,978,492
Ensembl chr37:15,939,138...15,977,556
JBrowse link
G CSF1 colony stimulating factor 1 acts_upstream_of_or_within
involved_in
ISO (MGI:3689489|PMID:17053831), (MGI:4849322|PMID:21048959)
(PMID:15304486)
(MGI:893319|PMID:9215625)
(MGI:3528531|PMID:15657444)
MGI
BHF-UCL
PMID:9215625 PMID:15304486 PMID:15657444 PMID:17053831 PMID:21048959 MGI:3528531 MGI:3689489 MGI:4849322 MGI:893319 NCBI chr 6:42,028,454...42,047,028
Ensembl chr 6:42,034,149...42,049,371
JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO RGD PMID:17121910 RGD:2293713 NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5495340|PMID:23395171) Ensembl
MGI
PMID:23395171 GO_REF:0000107 MGI:5495340 NCBI chr 8:48,330,856...48,334,273
Ensembl chr 8:48,331,026...48,333,467
JBrowse link
G GNAS GNAS complex locus acts_upstream_of_or_within ISO (MGI:3619837|PMID:15797856) MGI PMID:15797856 MGI:3619837 NCBI chr24:43,643,409...43,658,641
Ensembl chr24:43,643,405...43,658,657
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:28731198 RGD:13792731 NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666
JBrowse link
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G IL12B interleukin 12B involved_in ISO (PMID:17888176) BHF-UCL PMID:17888176 NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228
JBrowse link
G IL17A interleukin 17A involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513
JBrowse link
G IL20 interleukin 20 acts_upstream_of_or_within ISO (MGI:5296273|PMID:21844205) MGI PMID:21844205 MGI:5296273 NCBI chr 7:6,019,879...6,022,707
Ensembl chr 7:6,019,442...6,023,219
JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359
JBrowse link
G KLF10 Kruppel like factor 10 acts_upstream_of_or_within ISO (MGI:3528531|PMID:15657444) MGI PMID:15657444 MGI:3528531 NCBI chr13:4,216,745...4,223,708
Ensembl chr13:4,218,084...4,223,691
JBrowse link
G NOTCH2 notch receptor 2 involved_in ISO (MGI:3814108|PMID:18710934) UniProt PMID:18710934 MGI:3814108 NCBI chr17:56,854,825...57,020,157
Ensembl chr17:56,860,429...57,020,857
JBrowse link
G OCSTAMP osteoclast stimulatory transmembrane protein involved_in ISO (MGI:5319606|PMID:18064667) UniProt PMID:18064667 MGI:5319606 NCBI chr24:33,796,582...33,802,385
Ensembl chr24:33,796,027...33,802,270
JBrowse link
G POU4F1 POU class 4 homeobox 1 involved_in ISO (MGI:5825429|PMID:17668438) UniProt PMID:17668438 MGI:5825429 NCBI chr22:31,992,657...31,997,066 JBrowse link
G POU4F2 POU class 4 homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:45,030,818...45,034,446
Ensembl chr15:45,031,094...45,032,784
JBrowse link
G PPARGC1B PPARG coactivator 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:59,167,041...59,278,977
Ensembl chr 4:59,174,604...59,279,464
JBrowse link
G TMEM64 transmembrane protein 64 acts_upstream_of_or_within ISO (MGI:5495340|PMID:23395171) MGI PMID:23395171 MGI:5495340 NCBI chr29:36,005,600...36,030,366
Ensembl chr29:35,870,805...36,030,375
JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
G TNFSF11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in
ISO (MGI:5295788|PMID:21982707)
(MGI:3528531|PMID:15657444), (MGI:3575849|PMID:15724149)
(MGI:3689489|PMID:17053831), (MGI:4849322|PMID:21048959)
(PMID:15304486), (PMID:17241109), (PMID:19560569)
RGD
MGI
UniProt
PMID:11092398 PMID:15304486 PMID:15657444 PMID:15724149 PMID:17053831 More... MGI:3528531 MGI:3575849 MGI:3689489 MGI:4849322 MGI:5295788 RGD:730134 NCBI chr22:8,226,931...8,257,926
Ensembl chr22:8,227,555...8,258,645
JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in ISO (PMID:17135271) UniProt PMID:17135271 NCBI chr18:31,674,242...31,689,160
Ensembl chr18:31,675,391...31,688,641
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13969
    cellular process 13228
      positive regulation of cellular process 5598
        positive regulation of cell differentiation 955
          positive regulation of myeloid cell differentiation 111
            positive regulation of myeloid leukocyte differentiation 67
              positive regulation of granulocyte differentiation + 11
              positive regulation of macrophage differentiation + 16
              positive regulation of mast cell differentiation 3
              positive regulation of monocyte differentiation 10
              positive regulation of osteoclast differentiation + 29
Path 2
Term Annotations click to browse term
  biological_process 13969
    developmental process 6202
      anatomical structure development 5772
        multicellular organism development 5261
          system development 4930
            immune system development 1042
              hematopoietic or lymphoid organ development 978
                hemopoiesis 930
                  leukocyte differentiation 583
                    myeloid leukocyte differentiation 234
                      regulation of myeloid leukocyte differentiation 127
                        positive regulation of myeloid leukocyte differentiation 67
                          positive regulation of granulocyte differentiation + 11
                          positive regulation of macrophage differentiation + 16
                          positive regulation of mast cell differentiation 3
                          positive regulation of monocyte differentiation 10
                          positive regulation of osteoclast differentiation + 29
paths to the root