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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of myeloid leukocyte differentiation
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Accession:GO:0002763 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.
Synonyms:exact_synonym: up regulation of myeloid leukocyte differentiation;   upregulation of myeloid leukocyte differentiation
 narrow_synonym: activation of myeloid leukocyte differentiation;   stimulation of myeloid leukocyte differentiation


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positive regulation of myeloid leukocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd101 CD101 molecule acts_upstream_of_or_within ISO (MGI:5287956|PMID:21613616) MGI PMID:21613616 MGI:5287956 NCBI chrNW_004955435:20,104,391...20,145,440
Ensembl chrNW_004955435:20,103,716...20,142,983
JBrowse link
G Kitlg KIT ligand acts_upstream_of_or_within ISO (MGI:49671|PMID:1375116), (MGI:63529|PMID:7690439) MGI PMID:1375116 PMID:7690439 MGI:49671 MGI:63529 NCBI chrNW_004955405:25,816,137...25,969,006
Ensembl chrNW_004955405:25,886,447...25,969,395
JBrowse link
positive regulation of eosinophil differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il5 interleukin 5 ISO RGD PMID:10529595 PMID:10727846 RGD:2303509 RGD:2303750 NCBI chrNW_004955408:3,937,128...3,951,784
Ensembl chrNW_004955408:3,937,894...3,939,358
JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in ISO (MGI:5488531|PMID:23515163) CACAO PMID:23515163 MGI:5488531 NCBI chrNW_004955461:494,003...501,928
Ensembl chrNW_004955461:494,003...501,990
JBrowse link
positive regulation of granulocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Evi2b ecotropic viral integration site 2B involved_in ISO (PMID:28186500) UniProt PMID:28186500 NCBI chrNW_004955481:6,332,220...6,342,374
Ensembl chrNW_004955481:6,332,714...6,334,072
JBrowse link
G Gfi1b growth factor independent 1B transcriptional repressor involved_in ISO (MGI:5284774|PMID:17707228) UniProt PMID:17707228 MGI:5284774 NCBI chrNW_004955513:2,273,267...2,281,850
Ensembl chrNW_004955513:2,277,981...2,281,515
JBrowse link
G Hax1 HCLS1 associated protein X-1 involved_in ISO (PMID:23001182) BHF-UCL PMID:23001182 NCBI chrNW_004955545:816,789...819,667 JBrowse link
G Hcls1 hematopoietic cell-specific Lyn substrate 1 involved_in ISO (PMID:23001182)
(MGI:5448611|PMID:23001182)
BHF-UCL PMID:23001182 MGI:5448611 NCBI chrNW_004955427:20,999,934...21,020,401
Ensembl chrNW_004955427:20,999,485...21,020,531
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in ISO (PMID:19620402)
(PMID:23001182)
UniProt
BHF-UCL
PMID:19620402 PMID:23001182 NCBI chrNW_004955496:1,728,840...1,827,749
Ensembl chrNW_004955496:1,728,840...1,828,698
JBrowse link
G Tesc tescalcin involved_in ISO (PMID:20060826) UniProt PMID:20060826 NCBI chrNW_004955455:14,053,918...14,092,637
Ensembl chrNW_004955455:14,053,443...14,092,637
JBrowse link
positive regulation of macrophage differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp8 caspase 8 involved_in ISO (PMID:17047155) UniProt PMID:17047155 NCBI chrNW_004955403:322,082...348,591
Ensembl chrNW_004955403:322,555...347,053
JBrowse link
G Csf1 colony stimulating factor 1 involved_in
acts_upstream_of_or_within
ISO (PMID:2460758)
(MGI:893319|PMID:9215625)
BHF-UCL
MGI
PMID:2460758 PMID:9215625 MGI:893319 NCBI chrNW_004955435:13,404,236...13,423,059
Ensembl chrNW_004955435:13,404,508...13,424,247
JBrowse link
G Fadd Fas associated via death domain involved_in ISO (PMID:17047155) UniProt PMID:17047155 NCBI chrNW_004955422:16,026,323...16,035,808
Ensembl chrNW_004955422:16,031,280...16,036,281
JBrowse link
G Hcls1 hematopoietic cell-specific Lyn substrate 1 involved_in ISO (MGI:5448611|PMID:23001182) BHF-UCL PMID:23001182 MGI:5448611 NCBI chrNW_004955427:20,999,934...21,020,401
Ensembl chrNW_004955427:20,999,485...21,020,531
JBrowse link
G Hsf1 heat shock transcription factor 1 involved_in ISO (PMID:24504023) ARUK-UCL PMID:24504023 NCBI chrNW_004955454:2,907,265...2,932,352
Ensembl chrNW_004955454:2,907,265...2,932,351
JBrowse link
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO (MGI:3525032|PMID:15616565) MGI PMID:15616565 MGI:3525032 NCBI chrNW_004955487:878,326...880,783
Ensembl chrNW_004955487:878,326...880,783
JBrowse link
G Il34 interleukin 34 involved_in ISO (PMID:23409120) CACAO PMID:23409120 NCBI chrNW_004955484:3,362,240...3,429,031
Ensembl chrNW_004955484:3,416,965...3,428,574
JBrowse link
G Lif LIF interleukin 6 family cytokine acts_upstream_of_or_within ISO (PMID:7957045) MGI PMID:7957045 NCBI chrNW_004955455:4,489,515...4,505,439
Ensembl chrNW_004955455:4,489,421...4,497,940
JBrowse link
G Prkca protein kinase C alpha involved_in ISO (MGI:5306334|PMID:9508782) UniProt PMID:9508782 MGI:5306334 NCBI chrNW_004955478:5,686,639...6,090,356
Ensembl chrNW_004955478:5,686,640...6,083,967
JBrowse link
G Rb1 RB transcriptional corepressor 1 acts_upstream_of_or_within ISO (MGI:3525032|PMID:15616565) MGI PMID:15616565 MGI:3525032 NCBI chrNW_004955431:1,960,765...2,124,576
Ensembl chrNW_004955431:1,960,661...2,124,576
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:17047155) UniProt PMID:17047155 NCBI chrNW_004955465:10,127,907...10,167,895
Ensembl chrNW_004955465:10,128,931...10,168,399
JBrowse link
G Ror2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:25749876 RGD:11537353 NCBI chrNW_004955515:313,612...554,751
Ensembl chrNW_004955515:313,604...553,774
JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in ISO (MGI:5488531|PMID:23515163) CACAO PMID:23515163 MGI:5488531 NCBI chrNW_004955461:494,003...501,928
Ensembl chrNW_004955461:494,003...501,990
JBrowse link
positive regulation of mast cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgam integrin subunit alpha M involved_in ISO (MGI:1328479|PMID:9862668) UniProt PMID:9862668 MGI:1328479 NCBI chrNW_004955493:8,116,886...8,160,806
Ensembl chrNW_004955493:8,116,834...8,260,759
JBrowse link
G Pla2g3 phospholipase A2 group III involved_in ISO (MGI:5492190|PMID:23624557) UniProt PMID:23624557 MGI:5492190 NCBI chrNW_004955455:5,314,520...5,320,151
Ensembl chrNW_004955455:5,315,450...5,320,053
JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO (MGI:3605581|PMID:15947484) MGI PMID:15947484 MGI:3605581 NCBI chrNW_004955451:16,305,363...16,319,219 JBrowse link
positive regulation of microglia differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor beta 1 involved_in ISO (MGI:6192878|PMID:29909984) UniProt PMID:29909984 MGI:6192878 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441
JBrowse link
positive regulation of monocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acin1 apoptotic chromatin condensation inducer 1 involved_in ISO (PMID:12393560) UniProt PMID:12393560 NCBI chrNW_004955409:37,206,675...37,246,851
Ensembl chrNW_004955409:37,206,675...37,246,922
JBrowse link
G Cd4 CD4 molecule involved_in ISO (PMID:24942581) CAFA PMID:24942581 NCBI chrNW_004955413:4,400,326...4,422,110
Ensembl chrNW_004955413:4,408,390...4,421,535
JBrowse link
G Cd74 CD74 molecule involved_in ISO (PMID:24942581) CAFA PMID:24942581 NCBI chrNW_004955415:4,129,151...4,138,336
Ensembl chrNW_004955415:4,129,254...4,137,826
JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within ISO (MGI:893319|PMID:9215625) MGI PMID:9215625 MGI:893319 NCBI chrNW_004955435:13,404,236...13,423,059
Ensembl chrNW_004955435:13,404,508...13,424,247
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein involved_in ISO (MGI:5319610|PMID:17713547) UniProt PMID:17713547 MGI:5319610 NCBI chrNW_004955417:28,156,046...28,169,481
Ensembl chrNW_004955417:28,155,842...28,168,049
JBrowse link
G Fes FES proto-oncogene, tyrosine kinase involved_in ISO (PMID:28389358) ARUK-UCL PMID:28389358 NCBI chrNW_004955416:14,948,121...14,959,035
Ensembl chrNW_004955416:14,948,123...14,960,005
JBrowse link
G Il34 interleukin 34 involved_in ISO (PMID:23409120) CACAO PMID:23409120 NCBI chrNW_004955484:3,362,240...3,429,031
Ensembl chrNW_004955484:3,416,965...3,428,574
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO murine WEHI-3B D+ cells with or without retinoic acid RGD PMID:7947389 RGD:2291846 NCBI chrNW_004955464:1,107,598...1,110,326 JBrowse link
G Zfp36l1 ZFP36 ring finger protein like 1 involved_in ISO (PMID:26542173) UniProt PMID:26542173 NCBI chrNW_004955466:1,541,367...1,546,617
Ensembl chrNW_004955466:1,541,323...1,546,617
JBrowse link
positive regulation of neutrophil differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (MGI:2654310|PMID:12406904) MGI PMID:12406904 MGI:2654310 NCBI chrNW_004955456:3,617,988...3,721,791
Ensembl chrNW_004955456:3,635,380...3,721,791
JBrowse link
positive regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr68 G protein-coupled receptor 68 acts_upstream_of_or_within ISO (MGI:3848292|PMID:19479052) MGI PMID:19479052 MGI:3848292 NCBI chrNW_004955438:13,553,770...13,575,093
Ensembl chrNW_004955438:13,555,379...13,559,465
JBrowse link
G Ninj1 ninjurin 1 involved_in ISO (MGI:6458683|PMID:30700695) UniProt PMID:30700695 MGI:6458683 NCBI chrNW_004955515:4,892,748...4,905,627
Ensembl chrNW_004955515:4,892,039...4,907,323
JBrowse link
G Slc9b2 solute carrier family 9 member B2 acts_upstream_of_or_within ISO (MGI:3785147|PMID:18269914) MGI PMID:18269914 MGI:3785147 NCBI chrNW_004955496:5,532,113...5,587,801
Ensembl chrNW_004955496:5,552,422...5,581,987
JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within ISO (MGI:3785147|PMID:18269914), (MGI:5489769|PMID:22437732), (MGI:5522615|PMID:23980096) MGI PMID:18269914 PMID:22437732 PMID:23980096 MGI:3785147 MGI:5489769 MGI:5522615 NCBI chrNW_004955518:431,401...462,063
Ensembl chrNW_004955518:430,642...462,705
JBrowse link
G Tyrobp transmembrane immune signaling adaptor TYROBP involved_in ISO (MGI:3653295|PMID:14969392) UniProt PMID:14969392 MGI:3653295 NCBI chrNW_004955468:2,673,657...2,677,633
Ensembl chrNW_004955468:2,673,980...2,677,321
JBrowse link
positive regulation of osteoclast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asxl2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO (MGI:5514358|PMID:21490954) MGI PMID:21490954 MGI:5514358 NCBI chrNW_004955469:7,786,030...7,923,739
Ensembl chrNW_004955469:7,786,154...7,923,500
JBrowse link
G Ca2 carbonic anhydrase 2 ISO RGD PMID:10523502 RGD:1600711 NCBI chrNW_004955417:3,388,110...3,402,798
Ensembl chrNW_004955417:3,386,087...3,402,363
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO RGD PMID:9920817 RGD:2303108 NCBI chrNW_004955481:10,293,758...10,301,118
Ensembl chrNW_004955481:10,293,399...10,301,143
JBrowse link
G Creb1 cAMP responsive element binding protein 1 acts_upstream_of_or_within ISO (MGI:5495340|PMID:23395171) MGI PMID:23395171 MGI:5495340 NCBI chrNW_004955457:7,424,403...7,490,630
Ensembl chrNW_004955457:7,431,736...7,491,149
JBrowse link
G Csf1 colony stimulating factor 1 involved_in
acts_upstream_of_or_within
ISO (PMID:15304486)
(MGI:893319|PMID:9215625)
(MGI:3689489|PMID:17053831), (MGI:4849322|PMID:21048959)
(MGI:3528531|PMID:15657444)
BHF-UCL
MGI
PMID:9215625 PMID:15304486 PMID:15657444 PMID:17053831 PMID:21048959 MGI:3528531 MGI:3689489 MGI:4849322 MGI:893319 NCBI chrNW_004955435:13,404,236...13,423,059
Ensembl chrNW_004955435:13,404,508...13,424,247
JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO RGD PMID:17121910 RGD:2293713 NCBI chrNW_004955415:4,434,486...4,462,505
Ensembl chrNW_004955415:4,434,453...4,461,751
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (MGI:5495340|PMID:23395171) MGI PMID:23395171 MGI:5495340 NCBI chrNW_004955523:307,181...310,728
Ensembl chrNW_004955523:305,728...310,728
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO RGD PMID:28731198 RGD:13792731 NCBI chrNW_004955427:19,489,972...19,671,137
Ensembl chrNW_004955427:19,495,422...19,671,137
JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:16220542) BHF-UCL PMID:16220542 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045
JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:17888176) BHF-UCL PMID:17888176 NCBI chrNW_004955408:13,302,506...13,316,300
Ensembl chrNW_004955408:13,304,219...13,312,620
JBrowse link
G Il17a interleukin 17A involved_in ISO (PMID:17888176) BHF-UCL PMID:17888176 NCBI chrNW_004955411:5,896,435...5,899,911
Ensembl chrNW_004955411:5,896,702...5,900,962
JBrowse link
G Il20 interleukin 20 acts_upstream_of_or_within ISO (MGI:5296273|PMID:21844205) MGI PMID:21844205 MGI:5296273 NCBI chrNW_004955406:42,398,510...42,401,561
Ensembl chrNW_004955406:42,398,782...42,401,490
JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:17888176) BHF-UCL PMID:17888176 NCBI chrNW_004955458:3,946,964...3,949,180
Ensembl chrNW_004955458:3,947,803...3,949,312
JBrowse link
G Klf10 Kruppel like factor 10 acts_upstream_of_or_within ISO (MGI:3528531|PMID:15657444) MGI PMID:15657444 MGI:3528531 NCBI chrNW_004955417:27,165,146...27,168,604
Ensembl chrNW_004955417:27,164,839...27,168,604
JBrowse link
G Notch2 notch receptor 2 involved_in ISO (MGI:3814108|PMID:18710934) UniProt PMID:18710934 MGI:3814108 NCBI chrNW_004955568:1,660,357...1,812,285
Ensembl chrNW_004955568:1,660,731...1,809,173
JBrowse link
G Ocstamp osteoclast stimulatory transmembrane protein involved_in ISO (MGI:5319606|PMID:18064667) UniProt PMID:18064667 MGI:5319606 NCBI chrNW_004955445:10,836,404...10,842,811
Ensembl chrNW_004955445:10,836,545...10,842,410
JBrowse link
G Pou4f1 POU class 4 homeobox 1 involved_in ISO (MGI:5825429|PMID:17668438) UniProt PMID:17668438 MGI:5825429 NCBI chrNW_004955404:28,812,762...28,818,024 JBrowse link
G Pou4f2 POU class 4 homeobox 2 involved_in ISO (MGI:5825429|PMID:17668438) UniProt PMID:17668438 MGI:5825429 NCBI chrNW_004955428:2,325,775...2,329,122
Ensembl chrNW_004955428:2,324,834...2,329,205
JBrowse link
G Ppargc1b PPARG coactivator 1 beta involved_in ISO (MGI:3838421|PMID:19252502) DFLAT PMID:19252502 MGI:3838421 NCBI chrNW_004955415:4,638,057...4,756,885
Ensembl chrNW_004955415:4,644,998...4,757,093
JBrowse link
G Tmem64 transmembrane protein 64 acts_upstream_of_or_within ISO (MGI:5495340|PMID:23395171) MGI PMID:23395171 MGI:5495340 NCBI chrNW_004955417:7,436,690...7,483,190 JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:17888176) BHF-UCL PMID:17888176 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in
ISO (MGI:3528531|PMID:15657444), (MGI:3575849|PMID:15724149)
(MGI:3689489|PMID:17053831), (MGI:4849322|PMID:21048959)
(MGI:5295788|PMID:21982707)
(PMID:15304486), (PMID:17241109), (PMID:19560569)
RGD
MGI
UniProt
PMID:11092398 PMID:15304486 PMID:15657444 PMID:15724149 PMID:17053831 More... MGI:3528531 MGI:3575849 MGI:3689489 MGI:4849322 MGI:5295788 RGD:730134 NCBI chrNW_004955518:431,401...462,063
Ensembl chrNW_004955518:430,642...462,705
JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:17135271) UniProt PMID:17135271 NCBI chrNW_004955422:9,925,765...9,950,354
Ensembl chrNW_004955422:9,932,680...9,949,100
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6294223|PMID:16418779) UniProt PMID:16418779 MGI:6294223 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12096
    cellular process 11356
      positive regulation of cellular process 5144
        positive regulation of cell differentiation 905
          positive regulation of myeloid cell differentiation 103
            positive regulation of myeloid leukocyte differentiation 60
              positive regulation of granulocyte differentiation + 9
              positive regulation of macrophage differentiation + 14
              positive regulation of mast cell differentiation 3
              positive regulation of monocyte differentiation 9
              positive regulation of osteoclast differentiation + 28
Path 2
Term Annotations click to browse term
  biological_process 12096
    developmental process 5735
      anatomical structure development 5360
        multicellular organism development 4908
          system development 4605
            immune system development 956
              hematopoietic or lymphoid organ development 898
                hemopoiesis 852
                  leukocyte differentiation 542
                    myeloid leukocyte differentiation 217
                      regulation of myeloid leukocyte differentiation 116
                        positive regulation of myeloid leukocyte differentiation 60
                          positive regulation of granulocyte differentiation + 9
                          positive regulation of macrophage differentiation + 14
                          positive regulation of mast cell differentiation 3
                          positive regulation of monocyte differentiation 9
                          positive regulation of osteoclast differentiation + 28
paths to the root