Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:immune response-activating signaling pathway
go back to main search page
Accession:GO:0002757 term browser browse the term
Definition:The series of molecular signals generated by a ligand binding to its receptor that lead to the activation or perpetuation of an immune response.
Synonyms:exact_synonym: immune response-activating signal transduction

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
immune response-activating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:95,388,469...95,398,305
Ensembl chr20:95,388,477...95,397,960 		JBrowse link
antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCAR1 BCAR1 scaffold protein, Cas family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:60,709,409...60,749,071
Ensembl chr 5:60,707,006...60,732,882 		JBrowse link
G CD19 CD19 molecule involved_in ISO (PMID:1373518) UniProt PMID:1373518 NCBI chr 5:26,140,703...26,145,447 JBrowse link
G LAX1 lymphocyte transmembrane adaptor 1 acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:15843560) MGI
TreeGrafter		 PMID:15843560 GO_REF:0000118 NCBI chr25:25,569,543...25,583,523
Ensembl chr25:25,567,555...25,581,798 		JBrowse link
G SH2B2 SH2B adaptor protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr28:10,862,922...10,900,967
Ensembl chr28:10,864,188...10,883,437 		JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (PMID:15214043) BHF-UCL PMID:15214043 NCBI chr 6:42,186,028...42,193,105 JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 6:42,186,238...42,194,115 JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:79,044,624...79,077,736
Ensembl chr22:79,044,619...79,055,776 		JBrowse link
B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:7,258,932...7,435,658
Ensembl chr12:7,256,648...7,312,734 		JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:60,709,409...60,749,071
Ensembl chr 5:60,707,006...60,732,882 		JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895 		JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:7,547,200...7,618,645
Ensembl chr 8:7,547,299...7,569,188 		JBrowse link
G BLNK B cell linker involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:89,345,040...89,426,741
Ensembl chr 9:89,345,725...89,401,375 		JBrowse link
G BTK Bruton tyrosine kinase involved_in ISO (PMID:15509800) ARUK-UCL PMID:15509800 NCBI chr  X:89,690,569...89,727,420 JBrowse link
G BTK Bruton tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 Ensembl chr  X:89,690,671...89,711,218 JBrowse link
G CD19 CD19 molecule acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:9254656) MGI
TreeGrafter		 PMID:9254656 GO_REF:0000118 NCBI chr 5:26,140,703...26,145,447 JBrowse link
G CD38 CD38 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:34,375,859...34,449,131
Ensembl chr27:34,376,271...34,449,425 		JBrowse link
G CD79A CD79a molecule involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:36,078,057...36,089,367 JBrowse link
G CD79B CD79b molecule involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:57,339,492...57,343,085
Ensembl chr16:57,339,457...57,343,358 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:89,637,176...89,644,436
Ensembl chr10:89,638,314...89,642,344 		JBrowse link
G FCRL5 Fc receptor like 5 acts_upstream_of ISO (PMID:23509253) MGI PMID:23509253 NCBI chr20:6,335,288...6,371,662
Ensembl chr20:6,335,569...6,370,125 		JBrowse link
G GRB2 growth factor receptor bound protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:46,264,818...46,346,426
Ensembl chr16:46,264,825...46,347,156 		JBrowse link
G KLHL6 kelch like family member 6 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr15:5,844,728...5,912,392
Ensembl chr15:5,845,721...5,913,734 		JBrowse link
G LAT2 linker for activation of T cells family member 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr28:8,848,971...8,865,558
Ensembl chr28:8,848,638...8,865,574 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:7499277) MGI PMID:7499277 NCBI chr20:100,582,718...100,618,041 JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 Ensembl chr20:100,583,452...100,618,015 JBrowse link
G LIME1 Lck interacting transmembrane adaptor 1 involved_in
acts_upstream_of_or_within 		IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:491,618...494,446
Ensembl chr 2:491,096...493,147 		JBrowse link
G LOC103230364 protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within 		IEA
ISO 		(PMID:9254656)
(PMID:7499277) 		Ensembl
MGI		 PMID:7499277 PMID:9254656 GO_REF:0000107 NCBI chr25:30,655,014...30,777,367
Ensembl chr25:30,653,044...30,777,303 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:51,919,656...52,057,376
Ensembl chr 8:51,919,808...52,057,959 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325 		JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISO (PMID:18955699) UniProt PMID:18955699 NCBI chr 4:82,702,378...82,887,491
Ensembl chr 4:82,706,738...82,788,152 		JBrowse link
G MNDA myeloid cell nuclear differentiation antigen involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:5,079,633...5,124,967
Ensembl chr20:5,079,632...5,095,868 		JBrowse link
G MS4A1 membrane spanning 4-domains A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:13,343,647...13,358,639
Ensembl chr 1:13,345,253...13,358,547 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr11:50,611,193...50,658,800 JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 Ensembl chr11:50,611,181...50,647,519 JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:15143214) MGI
TreeGrafter		 PMID:15143214 GO_REF:0000118 NCBI chr19:24,913,474...24,964,803
Ensembl chr19:24,918,238...24,964,033 		JBrowse link
G NFATC2 nuclear factor of activated T cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:12,412,935...12,585,275
Ensembl chr 2:12,430,744...12,540,131 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:50,589,494...50,711,472
Ensembl chr 7:50,589,856...50,711,498 		JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:79,044,624...79,077,736
Ensembl chr22:79,044,619...79,055,776 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:67,209,268...67,394,865
Ensembl chr 5:67,215,459...67,398,990 		JBrowse link
G PLEKHA1 pleckstrin homology domain containing A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:115,110,316...115,168,113
Ensembl chr 9:115,128,942...115,165,576 		JBrowse link
G PRKCB protein kinase C beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:21,558,608...21,940,536
Ensembl chr 5:21,558,441...21,943,864 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:6,977,480...6,994,525
Ensembl chr11:6,984,710...6,994,545 		JBrowse link
G RFTN1 raftlin, lipid raft linker 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:61,159,573...61,290,342
Ensembl chr15:61,159,930...61,289,965 		JBrowse link
G SH2B2 SH2B adaptor protein 2 acts_upstream_of_or_within
involved_in 		IEA Ensembl GO_REF:0000107 NCBI chr28:10,862,922...10,900,967
Ensembl chr28:10,864,188...10,883,437 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:68,259,509...68,404,167
Ensembl chr14:68,259,360...68,399,895 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within 		IEA Ensembl GO_REF:0000107 NCBI chr12:101,254,085...101,374,724
Ensembl chr12:101,260,061...101,349,856 		JBrowse link
G TEC tec protein tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:1,982,549...2,118,533
Ensembl chr27:2,024,719...2,117,763 		JBrowse link
G TMIGD2 transmembrane and immunoglobulin domain containing 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:4,032,790...4,040,261
Ensembl chr 6:4,032,715...4,039,987 		JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:25,631,104...26,023,854
Ensembl chr20:25,631,171...26,023,849 		JBrowse link
CARD8 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103234962 caspase recruitment domain-containing protein 8 involved_in ISO (PMID:31525884), (PMID:33053349), (PMID:33420028), (PMID:33420033) UniProt PMID:31525884 PMID:33053349 PMID:33420028 PMID:33420033 NCBI chr 6:41,446,890...41,500,098 JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:43,264,917...43,266,825
Ensembl chr23:43,264,336...43,266,993 		JBrowse link
G CLEC7A C-type lectin domain containing 7A acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:12719478) MGI
Ensembl		 PMID:12719478 GO_REF:0000107 NCBI chr11:9,989,520...10,007,442
Ensembl chr11:9,995,203...10,006,746 		JBrowse link
G FCN1 ficolin 1 involved_in ISO (PMID:21037097) UniProt PMID:21037097 NCBI chr12:3,227,790...3,236,161 JBrowse link
G FCN1 ficolin 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr12:3,231,325...3,236,174 JBrowse link
G FFAR2 free fatty acid receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,375,607...30,379,479
Ensembl chr 6:30,377,427...30,378,419 		JBrowse link
G LBP lipopolysaccharide binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:25,375,364...25,407,181
Ensembl chr 2:25,374,755...25,406,839 		JBrowse link
G MBL2 mannose binding lectin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:78,389,534...78,394,753
Ensembl chr 9:78,389,947...78,396,079 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:101,254,085...101,374,724
Ensembl chr12:101,260,061...101,349,856 		JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chr 7:100,239,533...100,565,955
Ensembl chr 7:100,258,441...100,260,795 		JBrowse link
cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CGAS cyclic GMP-AMP synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:1,697,446...1,723,626
Ensembl chr17:1,697,775...1,723,472 		JBrowse link
G DDX41 DEAD-box helicase 41 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:79,522,265...79,528,628
Ensembl chr23:79,522,479...79,527,570 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:42,153,576...42,160,903
Ensembl chr23:42,153,026...42,160,907 		JBrowse link
complement component C5a signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLVRA biliverdin reductase A acts_upstream_of_or_within ISO (PMID:30952817) MGI PMID:30952817 NCBI chr21:14,777,171...14,820,690
Ensembl chr21:14,773,621...14,820,782 		JBrowse link
G C3AR1 complement C3a receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chr11:8,128,192...8,135,517
Ensembl chr11:8,128,620...8,130,062 		JBrowse link
G C5AR1 complement C5a receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,633,540...40,651,839
Ensembl chr 6:40,633,448...40,652,845 		JBrowse link
G C5AR2 complement C5a receptor 2 involved_in IEA GOC GO_REF:0000108 NCBI chr 6:40,659,576...40,672,267
Ensembl chr 6:40,671,056...40,672,069 		JBrowse link
complement receptor mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in ISO (PMID:19162005) BHF-UCL PMID:19162005 NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698 		JBrowse link
G C3 complement C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,250,422...6,289,264 JBrowse link
G C3AR1 complement C3a receptor 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:8,128,192...8,135,517
Ensembl chr11:8,128,620...8,130,062 		JBrowse link
G C5AR1 complement C5a receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:40,633,540...40,651,839
Ensembl chr 6:40,633,448...40,652,845 		JBrowse link
G C5AR2 complement C5a receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:40,659,576...40,672,267
Ensembl chr 6:40,671,056...40,672,069 		JBrowse link
G CMKLR1 chemerin chemokine-like receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr11:103,485,378...103,486,722 JBrowse link
G CMKLR2 chemerin chemokine-like receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:91,947,418...91,994,064
Ensembl chr10:91,948,260...91,949,327 		JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:16360013), (PMID:22962438) ARUK-UCL PMID:16360013 PMID:22962438 NCBI chr25:21,787,237...21,909,462 JBrowse link
G FPR1 formyl peptide receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:44,568,338...44,574,614
Ensembl chr 6:44,568,501...44,569,559 		JBrowse link
G FPR2 formyl peptide receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:44,580,342...44,591,187
Ensembl chr 6:44,589,334...44,590,389 		JBrowse link
G FPR3 formyl peptide receptor 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:44,609,711...44,642,329
Ensembl chr 6:44,641,146...44,642,207 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:47,748,183...47,809,459
Ensembl chr17:47,765,699...47,804,378 		JBrowse link
G GPR33 G protein-coupled receptor 33 involved_in IEA TreeGrafter GO_REF:0000118
G ITGAM integrin subunit alpha M involved_in ISO (PMID:22632727) ARUK-UCL PMID:22632727 NCBI chr 5:27,957,162...28,042,697
Ensembl chr 5:27,957,324...28,042,691 		JBrowse link
G LTB4R leukotriene B4 receptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr24:1,294,453...1,301,113
Ensembl chr24:1,298,729...1,299,790 		JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:12,989,750...12,994,979
Ensembl chr 1:12,992,188...12,993,378 		JBrowse link
G RGCC regulator of cell cycle involved_in ISO (PMID:19162005) BHF-UCL PMID:19162005 NCBI chr 3:19,681,700...19,695,655
Ensembl chr 3:19,681,874...19,693,644 		JBrowse link
cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALPK1 alpha kinase 1 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:60,096,755...60,233,569
Ensembl chr 7:60,202,204...60,236,743 		JBrowse link
G BECN1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:63,469,187...63,482,627
Ensembl chr16:63,469,192...63,485,322 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:1,697,446...1,723,626
Ensembl chr17:1,697,775...1,723,472 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in ISO (PMID:23478265) UniProt PMID:23478265 NCBI chr  X:38,513,251...38,539,982
Ensembl chr  Y:689,380...706,092 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in IEA Ensembl GO_REF:0000107 Ensembl chr  X:38,512,983...38,525,055 JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:64,154,832...64,166,480
Ensembl chr16:64,154,984...64,166,500 		JBrowse link
G IFIH1 interferon induced with helicase C domain 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:47,676,799...47,732,310
Ensembl chr10:47,676,920...47,732,264 		JBrowse link
G IPO5 importin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:76,644,113...76,690,718
Ensembl chr 3:76,644,131...76,692,146 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,835,285...42,841,487
Ensembl chr 6:42,831,203...42,840,796 		JBrowse link
G IRF7 interferon regulatory factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:430,412...433,959
Ensembl chr 1:429,310...432,925 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:34,534,433...34,555,406
Ensembl chr 2:34,541,229...34,552,823 		JBrowse link
G RIGI RNA sensor RIG-I involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:47,729,040...47,800,995
Ensembl chr12:47,729,076...47,799,570 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:42,153,576...42,160,903
Ensembl chr23:42,153,026...42,160,907 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:60,136,162...60,182,354
Ensembl chr11:60,136,232...60,182,344 		JBrowse link
G TIFA TRAF interacting protein with forkhead associated domain involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:60,074,764...60,085,029
Ensembl chr 7:60,076,999...60,077,556 		JBrowse link
G TRAF3IP3 TRAF3 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:19,671,531...19,699,737
Ensembl chr25:19,671,693...19,695,356 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:28,726,357...28,752,389
Ensembl chr 1:28,734,380...28,747,092 		JBrowse link
G TRIM25 tripartite motif containing 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:36,496,829...36,522,427
Ensembl chr16:36,496,772...36,524,148 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:1,031,840...1,086,950
Ensembl chr16:1,035,250...1,087,013 		JBrowse link
endolysosomal toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WASHC4 WASH complex subunit 4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:100,333,806...100,395,930
Ensembl chr11:100,333,912...100,398,713 		JBrowse link
Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER1G Fc epsilon receptor Ig involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:2,763,412...2,767,774
Ensembl chr20:2,763,417...2,767,248 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:51,919,656...52,057,376
Ensembl chr 8:51,919,808...52,057,959 		JBrowse link
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER2 Fc epsilon receptor II involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:7,175,032...7,189,002
Ensembl chr 6:7,175,032...7,189,057 		JBrowse link
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:63,785,493...63,791,071
Ensembl chr11:63,786,041...63,790,473 		JBrowse link
G MYO1G myosin IG involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:13,710,572...13,727,055
Ensembl chr21:13,710,541...13,727,515 		JBrowse link
G NOS2 nitric oxide synthase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:21,533,011...21,576,645
Ensembl chr16:21,533,484...21,574,257 		JBrowse link
immune response-activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG6 BAG cochaperone 6 involved_in ISO (PMID:18852879) UniProt PMID:18852879
G LOC103221769 MHC class I polypeptide-related sequence B involved_in ISO (PMID:11491531) UniProt PMID:11491531 NCBI chr17:40,518,365...40,532,637 JBrowse link
G NCR3 natural cytotoxicity triggering receptor 3 involved_in ISO (PMID:18852879) UniProt PMID:18852879
inflammasome-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ELP6 elongator acetyltransferase complex subunit 6 acts_upstream_of_or_within ISO (PMID:30097576) MGI PMID:30097576 NCBI chr22:8,899,078...8,929,072 JBrowse link
G ELP6 elongator acetyltransferase complex subunit 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 Ensembl chr22:8,912,014...8,928,929 JBrowse link
innate immune response-activating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TLR4 toll like receptor 4 ISO RGD PMID:19226379 RGD:2312509 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFIH1 interferon induced with helicase C domain 1 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:47,676,799...47,732,310
Ensembl chr10:47,676,920...47,732,264 		JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:108,192,595...108,210,332
Ensembl chr11:108,192,509...108,213,333 		JBrowse link
MyD88-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRFIP2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chr15:2,231,423...2,362,394
Ensembl chr15:2,231,525...2,361,544 		JBrowse link
MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD180 CD180 molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:63,361,277...63,377,492
Ensembl chr 4:63,359,844...63,377,459 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chr 3:9,353,333...9,357,765 JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:83,003,266...83,017,397
Ensembl chr10:83,003,717...83,017,363 		JBrowse link
G LOC103219990 regenerating islet-derived protein 3-gamma involved_in ISO (PMID:17635956) UniProt PMID:17635956 NCBI chr14:28,213,731...28,217,299 JBrowse link
G LOC103227720 twinfilin-2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:13,581,102...13,598,830
Ensembl chr22:13,589,034...13,598,752
Ensembl chr22:13,589,034...13,598,752 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in
acts_upstream_of_or_within 		IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr15:1,276,804...1,281,811
Ensembl chr15:1,276,798...1,281,166 		JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chr 7:100,239,533...100,565,955
Ensembl chr 7:100,258,441...100,260,795 		JBrowse link
G TLR4 toll like receptor 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
G TLR6 toll like receptor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:11,439,288...11,461,580
Ensembl chr27:11,459,181...11,461,571 		JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 involved_in ISO (PMID:22011580) UniProt PMID:22011580 NCBI chr23:53,586,243...53,643,599
Ensembl chr23:53,587,008...53,621,489 		JBrowse link
MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRFIP2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chr15:2,231,423...2,362,394
Ensembl chr15:2,231,525...2,361,544 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:4,526,719...4,543,251
Ensembl chr 6:4,527,033...4,529,168 		JBrowse link
G TNIP3 TNFAIP3 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:68,416,674...68,519,097
Ensembl chr 7:68,422,328...68,454,143 		JBrowse link
negative regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFI16 interferon gamma inducible protein 16 involved_in ISO (PMID:30104205) UniProt PMID:30104205 NCBI chr20:4,891,816...4,933,476
Ensembl chr20:4,888,779...4,933,478 		JBrowse link
G PYDC5 pyrin domain containing 5 involved_in ISO (PMID:24531343) UniProt PMID:24531343
G TRIM11 tripartite motif containing 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:1,322,817...1,336,535
Ensembl chr25:1,323,528...1,335,504 		JBrowse link
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD22 CD22 molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:30,251,220...30,285,084
Ensembl chr 6:30,270,229...30,282,859 		JBrowse link
G CD300A CD300a molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,153,766...47,173,780
Ensembl chr16:47,154,437...47,170,038 		JBrowse link
G CD72 CD72 molecule involved_in ISO (PMID:1711157) UniProt PMID:1711157 NCBI chr12:44,979,721...44,985,821 JBrowse link
G CD72 CD72 molecule involved_in IEA Ensembl GO_REF:0000107 Ensembl chr12:44,979,845...44,985,176 JBrowse link
G FCGR2B Fc gamma receptor IIb involved_in ISO (PMID:24169826) ARUK-UCL PMID:24169826 NCBI chr20:2,398,425...2,413,328 JBrowse link
G FCRL3 Fc receptor like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,201,252...6,223,913
Ensembl chr20:6,202,200...6,224,479 		JBrowse link
G FCRL5 Fc receptor like 5 acts_upstream_of_or_within ISO (PMID:23509253) MGI PMID:23509253 NCBI chr20:6,335,288...6,371,662
Ensembl chr20:6,335,569...6,370,125 		JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:6,690,831...6,694,245
Ensembl chr16:6,686,667...6,693,804 		JBrowse link
G LPXN leupaxin involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:14,776,434...14,827,095
Ensembl chr 1:14,779,606...14,827,301 		JBrowse link
G PLCL2 phospholipase C like 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr15:61,745,338...61,940,176
Ensembl chr15:61,745,163...61,942,655 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:6,977,480...6,994,525
Ensembl chr11:6,984,710...6,994,545 		JBrowse link
negative regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AARS2 alanyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:27,855,688...27,869,427
Ensembl chr17:27,855,713...27,870,409 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698 		JBrowse link
G AURKB aurora kinase B involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:7,571,255...7,583,034
Ensembl chr16:7,570,538...7,582,959 		JBrowse link
G BANF1 barrier to autointegration nuclear assembly factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:8,254,186...8,255,571
Ensembl chr 1:8,253,884...8,255,572 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:1,697,446...1,723,626
Ensembl chr17:1,697,775...1,723,472 		JBrowse link
G IRGM immunity related GTPase M involved_in ISO (PMID:32715615) UniProt PMID:32715615 NCBI chr23:53,449,576...53,451,373 JBrowse link
G LYPLAL1 lysophospholipase like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:10,370,715...10,408,807
Ensembl chr25:10,370,814...10,408,767 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:35460603) UniProt PMID:35460603 NCBI chr25:3,350,798...3,405,040 JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr25:3,350,821...3,388,826 JBrowse link
G PCBP2 poly(rC) binding protein 2 involved_in ISO (PMID:35322803) UniProt PMID:35322803 NCBI chr11:49,548,615...49,580,962 JBrowse link
G PPP6C protein phosphatase 6 catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:12,964,706...13,007,339
Ensembl chr12:12,964,842...13,007,351 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:43,915,226...44,119,547
Ensembl chr 8:43,914,636...44,119,541 		JBrowse link
G SMPDL3A sphingomyelin phosphodiesterase acid like 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:50,996,472...51,017,056
Ensembl chr13:50,996,674...51,016,108 		JBrowse link
G SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:1,685,741...1,691,542
Ensembl chr 5:1,686,095...1,691,489 		JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in ISO (PMID:33476576) UniProt PMID:33476576 NCBI chr22:9,869,502...9,871,659 JBrowse link
G ZDHHC18 zDHHC palmitoyltransferase 18 involved_in ISO (PMID:35438208) UniProt PMID:35438208 NCBI chr20:105,907,293...105,941,233 JBrowse link
G ZDHHC18 zinc finger DHHC-type palmitoyltransferase 18 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr20:105,909,557...105,940,971 JBrowse link
negative regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITCH itchy E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:38,671,170...38,808,621
Ensembl chr 2:38,701,396...38,805,005 		JBrowse link
G MARCHF5 membrane associated ring-CH-type finger 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:85,569,190...85,621,864
Ensembl chr 9:85,569,116...85,623,244 		JBrowse link
G RNF39 ring finger protein 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:42,423,486...42,429,631
Ensembl chr17:42,424,126...42,428,787 		JBrowse link
G SEC14L1 SEC14 like lipid binding 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:44,490,927...44,565,922
Ensembl chr16:44,489,852...44,565,853 		JBrowse link
G TARBP2 TARBP2 subunit of RISC loading complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:49,601,634...49,607,097
Ensembl chr11:49,602,113...49,606,816 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:30,539,867...30,629,372
Ensembl chr21:30,540,791...30,629,345 		JBrowse link
G TSPAN6 tetraspanin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:88,940,666...88,948,459
Ensembl chr  X:88,942,300...88,948,069 		JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:18,546,694...18,591,239
Ensembl chr22:18,546,751...18,589,552 		JBrowse link
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QBP complement C1q binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:4,843,202...4,850,639
Ensembl chr16:4,843,438...4,850,600 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:64,154,832...64,166,480
Ensembl chr16:64,154,984...64,166,500 		JBrowse link
G RIOK3 RIO kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:57,048,500...57,078,770
Ensembl chr18:57,048,447...57,078,312 		JBrowse link
G TKFC triokinase and FMN cyclase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:12,495,058...12,508,693
Ensembl chr 1:12,495,477...12,507,927 		JBrowse link
negative regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300A CD300a molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,153,766...47,173,780
Ensembl chr16:47,154,437...47,170,038 		JBrowse link
G CD300LF CD300 molecule like family member f involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:46,944,701...46,963,559
Ensembl chr16:46,944,921...46,962,770 		JBrowse link
negative regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SARM1 sterile alpha and TIR motif containing 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr16:22,137,990...22,163,431
Ensembl chr16:22,138,588...22,162,893 		JBrowse link
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD17A abhydrolase domain containing 17A, depalmitoylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:1,678,836...1,687,370
Ensembl chr 6:1,676,438...1,687,353 		JBrowse link
G ABHD8 abhydrolase domain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:15,798,462...15,810,012
Ensembl chr 6:15,798,256...15,810,036 		JBrowse link
G CPTP ceramide-1-phosphate transfer protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:130,124,705...130,128,745
Ensembl chr20:130,125,790...130,126,711 		JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 involved_in ISO (PMID:34615873) UniProt PMID:34615873 NCBI chr23:52,111,500...52,169,043
Ensembl chr23:52,114,053...52,168,998 		JBrowse link
G FBXL2 F-box and leucine rich repeat protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:77,769,424...77,895,994
Ensembl chr15:77,769,748...77,878,340 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 involved_in ISO (PMID:36586411) UniProt PMID:36586411 NCBI chr 1:114,447,348...114,452,693
Ensembl chr 1:114,446,544...114,451,562 		JBrowse link
G IRGM immunity related GTPase M involved_in ISO (PMID:30612879) UniProt PMID:30612879 NCBI chr23:53,449,576...53,451,373 JBrowse link
G LAMP2 lysosomal associated membrane protein 2 involved_in ISO (PMID:36586411) UniProt PMID:36586411
G LOC103234962 caspase recruitment domain-containing protein 8 involved_in ISO (PMID:24517500) UniProt PMID:24517500 NCBI chr 6:41,446,890...41,500,098 JBrowse link
G MEFV MEFV innate immunity regulator, pyrin involved_in ISO (PMID:26347139) UniProt PMID:26347139 NCBI chr 5:2,971,323...2,991,501 JBrowse link
G MEFV MEFV innate immunity regulator, pyrin involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 5:2,971,419...2,981,911 JBrowse link
G NLRC3 NLR family CARD domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:3,241,552...3,262,763
Ensembl chr 5:3,242,242...3,262,261 		JBrowse link
G PYDC1 pyrin domain containing 1 NOT|involved_in ISO (PMID:24871464) UniProt PMID:24871464
G PYDC2 pyrin domain containing 2 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr15:85,626,825...85,627,115 JBrowse link
G PYDC2 pyrin domain containing 2 involved_in ISO (PMID:17339483), (PMID:24871464) UniProt PMID:17339483 PMID:24871464
G SIRT2 sirtuin 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:33,493,106...33,518,793
Ensembl chr 6:33,493,079...33,518,647 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:30,965,091...30,999,073
Ensembl chr17:30,994,357...30,999,087 		JBrowse link
G TRIM22 tripartite motif containing 22 involved_in ISO (PMID:21048113) UniProt PMID:21048113 NCBI chr 1:61,018,252...61,036,690
Ensembl chr 1:61,019,464...61,036,548 		JBrowse link
G TRIM65 tripartite motif containing 65 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:45,790,271...45,798,852
Ensembl chr16:45,791,865...45,797,952 		JBrowse link
G ZDHHC12 zDHHC palmitoyltransferase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:9,419,784...9,423,091
Ensembl chr12:9,419,852...9,422,774 		JBrowse link
negative regulation of non-canonical inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:61,351,047...61,393,541
Ensembl chr  X:61,351,054...61,394,305 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:35,537,103...35,553,396
Ensembl chr13:35,537,102...35,549,197 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERBIN erbb2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:62,123,012...62,267,832
Ensembl chr 4:62,182,705...62,268,617 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:19,792,807...19,855,784
Ensembl chr20:19,793,083...19,855,827 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:35,537,103...35,553,396
Ensembl chr13:35,537,102...35,549,197 		JBrowse link
G ZNRF4 zinc and ring finger 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:5,127,332...5,129,463
Ensembl chr 6:5,127,865...5,129,154 		JBrowse link
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QBP complement C1q binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:4,843,202...4,850,639
Ensembl chr16:4,843,438...4,850,600 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:64,154,832...64,166,480
Ensembl chr16:64,154,984...64,166,500 		JBrowse link
G GPATCH3 G-patch domain containing 3 involved_in ISO (PMID:28414768) UniProt PMID:28414768 NCBI chr20:105,853,831...105,873,276 JBrowse link
G GPATCH3 G-patch domain containing 3 involved_in IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 Ensembl chr20:105,867,845...105,872,764 JBrowse link
G NLRX1 NLR family member X1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:110,541,777...110,559,846
Ensembl chr 1:110,545,190...110,560,149 		JBrowse link
G NPLOC4 NPL4 homolog, ubiquitin recognition factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:73,499,737...73,570,753
Ensembl chr16:73,502,123...73,570,710 		JBrowse link
G RNF125 ring finger protein 125 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:48,665,694...48,712,371
Ensembl chr18:48,666,554...48,711,604 		JBrowse link
G SEC14L1 SEC14 like lipid binding 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:44,490,927...44,565,922
Ensembl chr16:44,489,852...44,565,853 		JBrowse link
G UFD1 ubiquitin recognition factor in ER associated degradation 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:6,275,834...6,305,940
Ensembl chr19:6,275,844...6,308,035 		JBrowse link
negative regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTN2A2 butyrophilin subfamily 2 member A2 acts_upstream_of_or_within ISO (PMID:23589618) MGI PMID:23589618 NCBI chr17:45,857,898...45,869,901
Ensembl chr17:45,744,451...45,868,941 		JBrowse link
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:94,333,046...94,581,327
Ensembl chr 9:94,376,055...94,574,678 		JBrowse link
G CBLB Cbl proto-oncogene B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr22:74,961,831...75,181,307
Ensembl chr22:74,961,859...75,178,548 		JBrowse link
G CD160 CD160 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:13,009,168...13,029,766
Ensembl chr20:13,012,460...13,020,466 		JBrowse link
G CSK C-terminal Src kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:8,667,657...8,688,850
Ensembl chr26:8,667,655...8,688,824 		JBrowse link
G DGKZ diacylglycerol kinase zeta involved_in ISO (PMID:12883552) UniProt PMID:12883552 NCBI chr 1:18,949,360...18,997,957
Ensembl chr 1:18,948,425...18,982,354 		JBrowse link
G DUSP22 dual specificity phosphatase 22 acts_upstream_of_or_within
involved_in 		IEA Ensembl GO_REF:0000107 NCBI chr17:71,798,515...71,855,642
Ensembl chr17:71,799,014...71,855,601 		JBrowse link
G DUSP3 dual specificity phosphatase 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:62,622,667...62,637,129
Ensembl chr16:62,622,663...62,637,127 		JBrowse link
G ELF1 E74 like ETS transcription factor 1 acts_upstream_of_or_within ISO (PMID:14738763) MGI PMID:14738763 NCBI chr 3:19,218,161...19,303,116
Ensembl chr 3:19,217,771...19,303,113 		JBrowse link
G EZR ezrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:86,342,954...86,399,827
Ensembl chr13:86,344,051...86,370,622 		JBrowse link
G ITPRIPL1 ITPRIP like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:745,194...748,203
Ensembl chr14:745,331...750,727 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:102,080,500...102,106,649
Ensembl chr20:102,080,508...102,106,729 		JBrowse link
G LGALS3 galectin 3 involved_in ISO (PMID:19706535) BHF-UCL PMID:19706535 NCBI chr24:32,311,343...32,328,335
Ensembl chr24:32,311,271...32,328,339 		JBrowse link
G LOC103224480 guanylate-binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:44,373,122...44,388,973
Ensembl chr20:44,380,314...44,386,713 		JBrowse link
G LOC103234774 CEA cell adhesion molecule 1 involved_in ISO (PMID:18424730) UniProt PMID:18424730 NCBI chr 6:36,708,368...36,731,729
Ensembl chr 6:36,708,311...36,730,189 		JBrowse link
G LOC103235563 leukocyte immunoglobulin-like receptor subfamily B member 2 involved_in ISO (PMID:22387553)
(PMID:16493035) 		BHF-UCL
ARUK-UCL		 PMID:16493035 PMID:22387553 NCBI chr 6:47,299,764...47,333,711 JBrowse link
G NCK1 NCK adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:53,501,152...53,595,500
Ensembl chr15:53,500,623...53,523,576 		JBrowse link
G PAWR pro-apoptotic WT1 regulator acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:75,132,547...75,219,633
Ensembl chr11:75,133,186...75,219,072 		JBrowse link
G PHPT1 phosphohistidine phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,338,205...1,340,143
Ensembl chr12:1,338,388...1,339,753 		JBrowse link
G PRNP prion protein (Kanno blood group) involved_in ISO (PMID:20145049) BHF-UCL PMID:20145049 NCBI chr 2:33,368,020...33,384,556
Ensembl chr 2:33,369,629...33,370,366 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:71,302,082...71,400,201
Ensembl chr18:71,310,577...71,345,960 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:18056643) UniProt PMID:18056643 NCBI chr20:19,792,807...19,855,784
Ensembl chr20:19,793,083...19,855,827 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:6,977,480...6,994,525
Ensembl chr11:6,984,710...6,994,545 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:17,137,896...17,328,836
Ensembl chr 1:17,135,907...17,328,590 		JBrowse link
G PVRIG PVR related immunoglobulin domain containing involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr28:12,843,568...12,845,648
Ensembl chr28:12,843,811...12,845,133 		JBrowse link
G SH2D1A SH2 domain containing 1A involved_in IEA Ensembl GO_REF:0000107
G SLA2 Src like adaptor 2 involved_in ISO (PMID:11891219) UniProt PMID:11891219
G THY1 Thy-1 cell surface antigen involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:110,787,213...110,791,536
Ensembl chr 1:110,783,877...110,791,569 		JBrowse link
G UBASH3A ubiquitin associated and SH3 domain containing A involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:86,279,762...86,330,281
Ensembl chr 2:86,280,198...86,332,756 		JBrowse link
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450) UniProt PMID:23609450 NCBI chr 3:56,037,628...56,048,509
Ensembl chr 3:56,042,149...56,047,680 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:51,919,656...52,057,376
Ensembl chr 8:51,919,808...52,057,959 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:10,158,951...10,268,286
Ensembl chr 8:10,159,421...10,268,323 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15220916) MGI PMID:15220916 NCBI chr 5:36,492,158...36,531,766
Ensembl chr 5:36,496,414...36,530,499 		JBrowse link
G TLR6 toll like receptor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:11,439,288...11,461,580
Ensembl chr27:11,459,181...11,461,571 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514) ARUK-UCL PMID:31134514 NCBI chr17:30,965,091...30,999,073
Ensembl chr17:30,994,357...30,999,087 		JBrowse link
negative regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:71,095,446...71,109,832
Ensembl chr 4:71,095,500...71,110,005 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:35,537,103...35,553,396
Ensembl chr13:35,537,102...35,549,197 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in ISO (PMID:21695056) CACAO PMID:21695056 NCBI chr12:94,462,867...94,512,313
Ensembl chr12:94,461,972...94,511,747 		JBrowse link
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450) UniProt PMID:23609450 NCBI chr 3:56,037,628...56,048,509
Ensembl chr 3:56,042,149...56,047,680 		JBrowse link
G BPIFB1 BPI fold containing family B member 1 involved_in ISO (PMID:21900486) UniProt PMID:21900486 NCBI chr 2:37,612,111...37,638,397 JBrowse link
G BPIFB1 BPI fold containing family B member 1 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 Ensembl chr 2:37,615,068...37,633,307 JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:17,802,030...18,017,648
Ensembl chr12:17,801,831...17,830,890 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:51,919,656...52,057,376
Ensembl chr 8:51,919,808...52,057,959 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:10,158,951...10,268,286
Ensembl chr 8:10,159,421...10,268,323 		JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:66,078,990...66,086,927
Ensembl chr16:66,079,089...66,090,685 		JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:23,341,090...23,367,414
Ensembl chr25:23,341,490...23,367,398 		JBrowse link
G SQSTM1 sequestosome 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:81,536,271...81,571,061
Ensembl chr23:81,558,082...81,574,830 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:30,539,867...30,629,372
Ensembl chr21:30,540,791...30,629,345 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:19412184) UniProt PMID:19412184 NCBI chr23:18,831,361...18,855,476
Ensembl chr23:18,833,262...18,833,969 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514)
(PMID:29407460) 		ARUK-UCL PMID:29407460 PMID:31134514 NCBI chr17:30,965,091...30,999,073
Ensembl chr17:30,994,357...30,999,087 		JBrowse link
G TRIM32 tripartite motif containing 32 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:22,893,689...22,906,913
Ensembl chr12:22,894,886...22,896,847 		JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:35,537,103...35,553,396
Ensembl chr13:35,537,102...35,549,197 		JBrowse link
negative regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103235264 leukocyte immunoglobulin-like receptor subfamily A member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:47,023,469...47,038,665
Ensembl chr 6:47,023,620...47,037,336 		JBrowse link
negative regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRAMD4 GRAM domain containing 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:29,068,166...29,175,646
Ensembl chr19:29,070,023...29,172,977 		JBrowse link
G LOC103235264 leukocyte immunoglobulin-like receptor subfamily A member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:47,023,469...47,038,665
Ensembl chr 6:47,023,620...47,037,336 		JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:92,809,373...92,833,048
Ensembl chr20:92,809,552...92,833,244 		JBrowse link
G PTPRS protein tyrosine phosphatase receptor type S involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:4,880,942...5,019,654
Ensembl chr 6:4,882,223...4,964,919 		JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:23,341,090...23,367,414
Ensembl chr25:23,341,490...23,367,398 		JBrowse link
negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB2 arrestin beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:4,191,040...4,202,382
Ensembl chr16:4,191,172...4,202,385 		JBrowse link
G CACTIN cactin, spliceosome C complex subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:3,369,445...3,386,684
Ensembl chr 6:3,369,279...3,383,226 		JBrowse link
G GPR108 G protein-coupled receptor 108 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,299,294...6,306,957
Ensembl chr 6:6,299,548...6,306,564 		JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:6,690,831...6,694,245
Ensembl chr16:6,686,667...6,693,804 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:61,868,817...61,920,896
Ensembl chr11:61,869,173...61,920,406 		JBrowse link
G IRF4 interferon regulatory factor 4 acts_upstream_of_or_within ISO (PMID:16236719) MGI PMID:16236719 NCBI chr17:71,739,920...71,758,811 JBrowse link
G IRF4 interferon regulatory factor 4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 Ensembl chr17:71,751,770...71,757,496 JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:37,632,748...37,741,100
Ensembl chr 1:37,632,710...37,741,330 		JBrowse link
G LRRC14 leucine rich repeat containing 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:138,732,276...138,736,348
Ensembl chr 8:138,734,046...138,735,804 		JBrowse link
G NFKBIL1 NFKB inhibitor like 1 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:40,428,001...40,440,386
Ensembl chr17:40,428,222...40,439,433 		JBrowse link
G NLRP6 NLR family pyrin domain containing 6 acts_upstream_of_or_within ISO (PMID:22763455) MGI PMID:22763455 NCBI chr 1:92,213...99,919 JBrowse link
G NLRP6 NLR family pyrin domain containing 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 Ensembl chr 1:93,334...98,972 JBrowse link
G OTUD4 OTU deubiquitinase 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:91,709,184...91,756,437
Ensembl chr 7:91,708,767...91,756,793 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (PMID:20584979) UniProt PMID:20584979
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) UniProt PMID:20728433 NCBI chr 9:89,750,792...89,875,309 JBrowse link
G RNF115 ring finger protein 115 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:12,919,988...13,001,736
Ensembl chr20:12,920,232...13,001,135 		JBrowse link
G SMPDL3B sphingomyelin phosphodiesterase acid like 3B involved_in ISO (PMID:26095358) UniProt PMID:26095358 NCBI chr20:104,852,055...104,872,123 JBrowse link
G TRIM22 tripartite motif containing 22 involved_in ISO (PMID:18345001) UniProt PMID:18345001 NCBI chr 1:61,018,252...61,036,690
Ensembl chr 1:61,019,464...61,036,548 		JBrowse link
G TYRO3 TYRO3 protein tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:41,429,667...41,449,130
Ensembl chr26:41,429,556...41,449,175 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:1,031,840...1,086,950
Ensembl chr16:1,035,250...1,087,013 		JBrowse link
NLRP1 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLRP1 NLR family pyrin domain containing 1 involved_in ISO (PMID:22665479), (PMID:33243852), (PMID:33420028), (PMID:33420033), (PMID:33852854), (PMID:35594856)
(PMID:27662089), (PMID:31484767) 		UniProt PMID:22665479 PMID:27662089 PMID:31484767 PMID:33243852 PMID:33420028 More... NCBI chr16:4,930,643...4,983,378 JBrowse link
G NLRP1 NLR family pyrin domain containing 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:4,944,892...4,982,285 JBrowse link
NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAT1 alpha tubulin acetyltransferase 1 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr17:41,807,405...41,830,670
Ensembl chr17:41,807,291...41,830,000 		JBrowse link
G GKN2 gastrokine 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:38,171,433...38,179,689
Ensembl chr14:38,172,306...38,179,457 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:21,624,963...21,634,940
Ensembl chr11:21,624,970...21,634,042 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 acts_upstream_of_or_within
involved_in 		ISO (PMID:22753929)
(PMID:17483456), (PMID:23582325), (PMID:25686105), (PMID:27043286), (PMID:27432880), (PMID:28465465), (PMID:28656979), (PMID:28943315), (PMID:30487600), (PMID:31189953), (PMID:33231615), (PMID:34554188), (PMID:34615873), (PMID:35114687), (PMID:35254907), (PMID:35559676), (PMID:36442502), (PMID:39173637)
(PMID:23582325), (PMID:26173909), (PMID:27043286), (PMID:28465465), (PMID:28656979), (PMID:28716882), (PMID:28943315), (PMID:30487600), (PMID:34615873), (PMID:34861190) 		MGI
UniProt		 PMID:17483456 PMID:22753929 PMID:23582325 PMID:25686105 PMID:26173909 More... NCBI chr25:84,431,436...84,463,387
Ensembl chr25:84,434,527...84,463,249 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:27,892,332...27,894,386
Ensembl chr 5:27,889,230...27,893,697 		JBrowse link
G SIRT2 sirtuin 2 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 6:33,493,106...33,518,793
Ensembl chr 6:33,493,079...33,518,647 		JBrowse link
NLRP6 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLRP6 NLR family pyrin domain containing 6 involved_in ISO (PMID:30674671), (PMID:31932628), (PMID:34678144)
(PMID:32424362), (PMID:34678144) 		UniProt PMID:30674671 PMID:31932628 PMID:32424362 PMID:34678144 NCBI chr 1:92,213...99,919 JBrowse link
G NLRP6 NLR family pyrin domain containing 6 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 1:93,334...98,972 JBrowse link
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF34 ring finger protein 34 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:116,777,294...116,800,816
Ensembl chr11:116,777,419...116,800,035 		JBrowse link
nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFKBIA NFKB inhibitor alpha acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:27,907,628...27,957,621
Ensembl chr21:27,926,710...27,957,619 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within 		IEA Ensembl GO_REF:0000107 NCBI chr 8:84,843,391...84,881,087
Ensembl chr 8:84,843,471...84,881,303 		JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of ISO (PMID:18261938) MGI PMID:18261938 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in ISO (PMID:29452636) UniProt PMID:29452636
nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INAVA innate immunity activator involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:28,488,990...28,513,997
Ensembl chr25:28,488,901...28,509,704 		JBrowse link
G IRF5 interferon regulatory factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:97,536,803...97,549,576
Ensembl chr21:97,537,790...97,549,945 		JBrowse link
G IRGM immunity related GTPase M involved_in ISO (PMID:25891078) UniProt PMID:25891078 NCBI chr23:53,449,576...53,451,373 JBrowse link
G LACC1 laccase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:21,995,405...22,008,310
Ensembl chr 3:21,997,133...22,006,418 		JBrowse link
G NFKBIA NFKB inhibitor alpha acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in 		IEA
ISO 		(PMID:27007849)
(PMID:12626759), (PMID:15044951), (PMID:17355968), (PMID:23806334), (PMID:31649195)
(PMID:15692052) 		Ensembl
UniProt		 PMID:12626759 PMID:15044951 PMID:15692052 PMID:17355968 PMID:23806334 More... GO_REF:0000107 NCBI chr 5:36,492,158...36,531,766
Ensembl chr 5:36,496,414...36,530,499 		JBrowse link
G OTULIN OTU deubiquitinase with linear linkage specificity involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:14,358,556...14,395,539
Ensembl chr 4:14,358,538...14,389,987 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within 		IEA
ISO 		(PMID:11894098) Ensembl
MGI		 PMID:11894098 GO_REF:0000107 NCBI chr 8:84,843,391...84,881,087
Ensembl chr 8:84,843,471...84,881,303 		JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of ISO (PMID:18261938) MGI PMID:18261938 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in ISO (PMID:19667203), (PMID:22607974), (PMID:29452636) UniProt PMID:19667203 PMID:22607974 PMID:29452636
pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CGAS cyclic GMP-AMP synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:1,697,446...1,723,626
Ensembl chr17:1,697,775...1,723,472 		JBrowse link
G CLEC4E C-type lectin domain family 4 member E involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:8,315,888...8,322,240
Ensembl chr11:8,316,049...8,321,274 		JBrowse link
G INAVA innate immunity activator involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:28,488,990...28,513,997
Ensembl chr25:28,488,901...28,509,704 		JBrowse link
G LACC1 laccase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:21,995,405...22,008,310
Ensembl chr 3:21,997,133...22,006,418 		JBrowse link
G LOC103227720 twinfilin-2 involved_in IEA UniProt GO_REF:0000117 NCBI chr22:13,581,102...13,598,830
Ensembl chr22:13,589,034...13,598,752
Ensembl chr22:13,589,034...13,598,752 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:27,907,628...27,957,621
Ensembl chr21:27,926,710...27,957,619 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:36,492,158...36,531,766
Ensembl chr 5:36,496,414...36,530,499 		JBrowse link
G RNF144A ring finger protein 144A involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:100,646,376...100,765,860
Ensembl chr14:100,644,270...100,743,634 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:42,153,576...42,160,903
Ensembl chr23:42,153,026...42,160,907 		JBrowse link
G TLR7 toll like receptor 7 involved_in IEA UniProt GO_REF:0000117 Ensembl chr  X:11,367,110...11,370,259 JBrowse link
G TLR8 toll like receptor 8 involved_in IEA UniProt GO_REF:0000117 NCBI chr  X:11,387,933...11,405,056
Ensembl chr  X:11,400,907...11,404,029 		JBrowse link
positive regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GBP2 guanylate binding protein 2 involved_in ISO (PMID:25774715), (PMID:25774716) UniProt PMID:25774715 PMID:25774716 NCBI chr20:44,253,290...44,280,335 JBrowse link
positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103230364 protein tyrosine phosphatase receptor type C involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:30,655,014...30,777,367
Ensembl chr25:30,653,044...30,777,303 		JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:2,190,896...2,211,838
Ensembl chr 1:2,190,845...2,211,389 		JBrowse link
G CMTM3 CKLF like MARVEL transmembrane domain containing 3 acts_upstream_of_or_within ISO (PMID:15196959) MGI PMID:15196959 NCBI chr 5:52,302,606...52,312,277
Ensembl chr 5:52,303,288...52,311,165 		JBrowse link
G FOXP1 forkhead box P1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:31,907,941...32,538,294
Ensembl chr22:31,912,460...32,154,502 		JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr19:24,913,474...24,964,803
Ensembl chr19:24,918,238...24,964,033 		JBrowse link
G PRKCH protein kinase C eta involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:38,489,535...38,726,028
Ensembl chr24:38,488,970...38,724,879 		JBrowse link
G SLC39A10 solute carrier family 39 member 10 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:81,143,658...81,273,010
Ensembl chr10:81,187,587...81,273,749 		JBrowse link
G STAP1 signal transducing adaptor family member 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:1,330,761...1,380,503
Ensembl chr 7:1,330,223...1,379,820 		JBrowse link
positive regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase involved_in ISO (PMID:25704810) UniProt PMID:25704810 NCBI chr  X:89,690,569...89,727,420 JBrowse link
G BTK Bruton tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 Ensembl chr  X:89,690,671...89,711,218 JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:37832545) UniProt PMID:37832545 NCBI chr13:15,284,927...15,360,539
Ensembl chr13:15,284,923...15,360,832 		JBrowse link
G MARCHF5 membrane associated ring-CH-type finger 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:85,569,190...85,621,864
Ensembl chr 9:85,569,116...85,623,244 		JBrowse link
G RNF39 ring finger protein 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:42,423,486...42,429,631
Ensembl chr17:42,424,126...42,428,787 		JBrowse link
G SLC19A1 solute carrier family 19 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:89,188,171...89,232,081
Ensembl chr 2:89,188,733...89,209,281 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 involved_in ISO (PMID:37832545) UniProt PMID:37832545 NCBI chr19:21,971,362...22,004,289 JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr19:21,988,922...22,002,627 JBrowse link
G ZDHHC9 zDHHC palmitoyltransferase 9 involved_in ISO (PMID:37802025) UniProt PMID:37802025 NCBI chr  X:105,082,531...105,120,802 JBrowse link
G ZDHHC9 zinc finger DHHC-type palmitoyltransferase 9 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr  X:105,090,824...105,120,787 JBrowse link
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD226 CD226 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:9,790,483...9,900,376
Ensembl chr18:9,811,168...9,901,830 		JBrowse link
G LOC103230364 protein tyrosine phosphatase receptor type C involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:30,655,014...30,777,367
Ensembl chr25:30,653,044...30,777,303 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:16177098 RGD:1578516 NCBI chr 8:51,919,656...52,057,376
Ensembl chr 8:51,919,808...52,057,959 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:17,137,896...17,328,836
Ensembl chr 1:17,135,907...17,328,590 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO RGD PMID:18832707 RGD:9835043 NCBI chr20:21,895,829...21,989,008
Ensembl chr20:21,899,669...21,917,350 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO RGD PMID:18832707 RGD:9835043 NCBI chr12:6,407,030...6,566,200
Ensembl chr12:6,437,454...6,567,436 		JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:100,400,093...100,469,234
Ensembl chr11:100,400,084...100,462,507 		JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR4A3 nuclear receptor subfamily 4 group A member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:39,568,085...39,611,704
Ensembl chr12:39,567,852...39,606,837 		JBrowse link
positive regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD17 ankyrin repeat domain 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:21,536,241...21,719,320
Ensembl chr 7:21,535,409...21,683,246 		JBrowse link
G DDX60 DExD/H-box helicase 60 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:114,474,678...114,578,749
Ensembl chr 7:114,474,680...114,578,563 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:64,154,832...64,166,480
Ensembl chr16:64,154,984...64,166,500 		JBrowse link
positive regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCDC134 coiled-coil domain containing 134 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:24,332,293...24,358,056
Ensembl chr19:24,332,316...24,357,583 		JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAT1 alpha tubulin acetyltransferase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:41,807,405...41,830,670
Ensembl chr17:41,807,291...41,830,000 		JBrowse link
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:129,358,759...129,406,293
Ensembl chr  X:129,358,862...129,403,352 		JBrowse link
G BTK Bruton tyrosine kinase involved_in ISO (PMID:34554188) UniProt PMID:34554188 NCBI chr  X:89,690,569...89,727,420 JBrowse link
G BTK Bruton tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 Ensembl chr  X:89,690,671...89,711,218 JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:68,214,875...68,309,336
Ensembl chr21:68,216,201...68,268,669 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in ISO (PMID:31511697) UniProt PMID:31511697 NCBI chr  X:38,513,251...38,539,982
Ensembl chr  Y:689,380...706,092 		JBrowse link
G DHX33 DEAH-box helicase 33 involved_in ISO (PMID:23871209) UniProt PMID:23871209 NCBI chr16:4,855,374...4,879,892 JBrowse link
G DHX33 DEAH-box helicase 33 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:4,855,652...4,879,902 JBrowse link
G KCNK6 potassium two pore domain channel subfamily K member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:32,959,275...32,977,601
Ensembl chr 6:32,962,535...32,973,196 		JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:21,901,153...21,966,227
Ensembl chr13:21,919,280...21,967,117 		JBrowse link
G LATS2 large tumor suppressor kinase 2 involved_in ISO (PMID:39173637) UniProt PMID:39173637 NCBI chr 3:124,520...215,426 JBrowse link
G LOC103248367 caspase-4 involved_in ISO (PMID:26173909) UniProt PMID:26173909 NCBI chr 1:96,315,781...96,342,057
Ensembl chr 1:96,315,569...96,342,016 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:43,356,603...43,489,066
Ensembl chr 9:43,356,308...43,393,425 		JBrowse link
G MARCHF5 membrane associated ring-CH-type finger 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:85,569,190...85,621,864
Ensembl chr 9:85,569,116...85,623,244 		JBrowse link
G MARK4 microtubule affinity regulating kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,710,593...38,761,548
Ensembl chr 6:38,710,467...38,760,561 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:34,534,433...34,555,406
Ensembl chr 2:34,541,229...34,552,823 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:1,276,804...1,281,811
Ensembl chr15:1,276,798...1,281,166 		JBrowse link
G NEK7 NIMA related kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:31,111,332...31,257,445
Ensembl chr25:31,110,616...31,257,374 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in ISO (PMID:29958799) UniProt PMID:29958799 NCBI chr11:116,505,975...116,560,151
Ensembl chr11:116,529,346...116,563,059 		JBrowse link
G PLCG2 phospholipase C gamma 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:67,209,268...67,394,865
Ensembl chr 5:67,215,459...67,398,990 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:36,999,110...37,028,916
Ensembl chr23:36,997,078...37,029,280 		JBrowse link
G PRKD1 protein kinase D1 involved_in IEA Ensembl GO_REF:0000107
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:19,792,807...19,855,784
Ensembl chr20:19,793,083...19,855,827 		JBrowse link
G STMP1 short transmembrane mitochondrial protein 1 involved_in ISO (PMID:31836654) UniProt PMID:31836654 NCBI chr21:104,340,369...104,352,965 JBrowse link
G TLR4 toll like receptor 4 involved_in ISO (PMID:23812099) UniProt PMID:23812099 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
G TLR6 toll like receptor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:11,439,288...11,461,580
Ensembl chr27:11,459,181...11,461,571 		JBrowse link
G USP50 ubiquitin specific peptidase 50 acts_upstream_of_or_within ISO (PMID:28094437) MGI PMID:28094437 NCBI chr26:32,785,817...32,830,148 JBrowse link
G USP50 ubiquitin specific peptidase 50 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 Ensembl chr26:32,786,271...32,792,010 JBrowse link
G ZDHHC1 zDHHC palmitoyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:60,040,264...60,062,531
Ensembl chr 5:60,040,266...60,062,548 		JBrowse link
G ZDHHC5 zDHHC palmitoyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:15,526,735...15,560,562
Ensembl chr 1:15,525,169...15,555,405 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:124,170,785...124,204,358
Ensembl chr11:124,169,732...124,204,200 		JBrowse link
G SLC46A2 solute carrier family 46 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:26,631,295...26,646,112
Ensembl chr12:26,633,493...26,646,038 		JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:24790089) UniProt PMID:24790089 NCBI chr17:40,203,647...40,206,028
Ensembl chr17:40,203,936...40,205,858 		JBrowse link
G LOC103221743 heat shock 70 kDa protein 1A involved_in ISO (PMID:24790089) UniProt PMID:24790089 NCBI chr17:40,191,695...40,194,459
Ensembl chr17:40,203,936...40,205,858 		JBrowse link
G NAGK N-acetylglucosamine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:36,086,624...36,098,465
Ensembl chr14:36,082,137...36,096,914 		JBrowse link
G PELI3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chr 1:7,800,430...7,811,226
Ensembl chr 1:7,799,182...7,811,208 		JBrowse link
G SLC15A3 solute carrier family 15 member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:12,896,612...12,910,740
Ensembl chr 1:12,895,982...12,912,214 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:124,170,785...124,204,358
Ensembl chr11:124,169,732...124,204,200 		JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
positive regulation of pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZDHHC5 zDHHC palmitoyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:15,526,735...15,560,562
Ensembl chr 1:15,525,169...15,555,405 		JBrowse link
positive regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD17 ankyrin repeat domain 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:21,536,241...21,719,320
Ensembl chr 7:21,535,409...21,683,246 		JBrowse link
G DDX60 DExD/H-box helicase 60 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:114,474,678...114,578,749
Ensembl chr 7:114,474,680...114,578,563 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:64,154,832...64,166,480
Ensembl chr16:64,154,984...64,166,500 		JBrowse link
G HDAC6 histone deacetylase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:45,927,625...45,951,636
Ensembl chr  X:45,928,092...45,952,929 		JBrowse link
G OASL 2'-5'-oligoadenylate synthetase like involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:116,376,806...116,396,239
Ensembl chr11:116,376,217...116,395,945 		JBrowse link
G PUM1 pumilio RNA binding family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:101,773,819...101,910,433
Ensembl chr20:101,773,960...101,910,519 		JBrowse link
G PUM2 pumilio RNA binding family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:87,368,288...87,473,282
Ensembl chr14:87,391,219...87,474,676 		JBrowse link
G TRIM15 tripartite motif containing 15 involved_in ISO (PMID:23077300) UniProt PMID:23077300 NCBI chr17:42,334,910...42,345,895 JBrowse link
G TRIM15 tripartite motif containing 15 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr17:42,335,630...42,343,745 JBrowse link
G USP15 ubiquitin specific peptidase 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:58,154,905...58,300,431
Ensembl chr11:58,154,919...58,300,522 		JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 involved_in ISO (PMID:21102435) UniProt PMID:21102435 NCBI chr21:107,770,270...107,808,575 JBrowse link
G ZCCHC3 zinc finger CCHC-type containing 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:35,422,903...35,426,145
Ensembl chr 2:35,423,430...35,424,638 		JBrowse link
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of_or_within ISO (PMID:11435465) MGI PMID:11435465 NCBI chr 2:19,167,209...19,200,233 JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:48,073,489...48,084,635
Ensembl chr20:48,073,800...48,085,136 		JBrowse link
G CARD11 caspase recruitment domain family member 11 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr28:18,675,524...18,715,388 JBrowse link
G CCR7 C-C motif chemokine receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:65,620,632...65,632,394
Ensembl chr16:65,620,665...65,632,984 		JBrowse link
G CD226 CD226 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:9,790,483...9,900,376
Ensembl chr18:9,811,168...9,901,830 		JBrowse link
G CD81 CD81 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:2,190,896...2,211,838
Ensembl chr 1:2,190,845...2,211,389 		JBrowse link
G CYLD CYLD lysine 63 deubiquitinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:36,541,022...36,600,874
Ensembl chr 5:36,541,764...36,595,417 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 involved_in ISO (PMID:18796614) BHF-UCL PMID:18796614 NCBI chr 6:37,289,088...37,316,850 JBrowse link
G LIPA lipase A, lysosomal acid type acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:82,639,220...82,677,479
Ensembl chr 9:82,638,621...82,677,488 		JBrowse link
G LOC103232832 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:128,781,975...128,816,039
Ensembl chr  X:128,787,785...128,806,083 		JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:38,320,791...38,361,419
Ensembl chr 6:38,320,933...38,361,742 		JBrowse link
G PRKD2 protein kinase D2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,028,214...40,071,523
Ensembl chr 6:40,027,552...40,071,455 		JBrowse link
G PVR PVR cell adhesion molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:38,127,864...38,141,612 JBrowse link
G RAB29 RAB29, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:23,572,001...23,579,881
Ensembl chr25:23,572,542...23,577,695 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516 		JBrowse link
G RPS3 ribosomal protein S3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:66,629,895...66,636,462
Ensembl chr 1:66,629,954...66,635,344 		JBrowse link
G TAOK3 TAO kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:113,485,871...113,717,213
Ensembl chr11:113,484,330...113,704,271 		JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:51,044,269...51,079,210
Ensembl chr11:51,042,095...51,070,939 		JBrowse link
G TRAT1 T cell receptor associated transmembrane adaptor 1 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr22:71,939,447...71,972,187
Ensembl chr22:71,939,207...71,972,172 		JBrowse link
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:29,458,388...29,590,706
Ensembl chr17:29,458,374...29,590,687 		JBrowse link
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYBA cytochrome b-245 alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:74,023,134...74,030,793
Ensembl chr 5:74,023,082...74,030,750 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:71,095,446...71,109,832
Ensembl chr 4:71,095,500...71,110,005 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:16267105) UniProt PMID:16267105 NCBI chr 3:9,353,333...9,357,765 JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:10,158,951...10,268,286
Ensembl chr 8:10,159,421...10,268,323 		JBrowse link
G PJA2 praja ring finger ubiquitin ligase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:12,753,505...12,825,279
Ensembl chr23:12,753,513...12,796,482 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:117,417,561...117,419,870 JBrowse link
G TLR1 toll like receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:11,482,307...11,490,847
Ensembl chr27:11,488,294...11,490,654 		JBrowse link
positive regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:71,095,446...71,109,832
Ensembl chr 4:71,095,500...71,110,005 		JBrowse link
G FLOT1 flotillin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:41,714,354...41,725,820
Ensembl chr17:41,714,402...41,725,397 		JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:42,864,857...42,930,315
Ensembl chr14:42,864,897...42,930,394 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:19,792,807...19,855,784
Ensembl chr20:19,793,083...19,855,827 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in ISO (PMID:17322885) BHF-UCL PMID:17322885 NCBI chr 1:117,417,561...117,419,870 JBrowse link
G TRIM3 tripartite motif containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:58,353,338...58,378,959
Ensembl chr 1:58,354,117...58,379,100 		JBrowse link
G WDFY1 WD repeat and FYVE domain containing 1 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:109,815,043...109,889,120
Ensembl chr10:109,818,422...109,889,023 		JBrowse link
positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:43,264,917...43,266,825
Ensembl chr23:43,264,336...43,266,993 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:71,095,446...71,109,832
Ensembl chr 4:71,095,500...71,110,005 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:16267105) UniProt PMID:16267105 NCBI chr 3:9,353,333...9,357,765 JBrowse link
G IFI35 interferon induced protein 35 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:63,276,493...63,284,196
Ensembl chr16:63,273,829...63,284,283 		JBrowse link
G LBP lipopolysaccharide binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:25,375,364...25,407,181
Ensembl chr 2:25,374,755...25,406,839 		JBrowse link
G LTF lactotransferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:7,867,332...7,896,403
Ensembl chr22:7,867,286...7,894,521 		JBrowse link
G NINJ1 ninjurin 1 involved_in ISO (PMID:25860173) UniProt PMID:25860173 NCBI chr12:103,509,950...103,523,158
Ensembl chr12:103,510,454...103,523,084 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:18,041,495...18,061,196
Ensembl chr 1:18,041,830...18,051,501 		JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:42,864,857...42,930,315
Ensembl chr14:42,864,897...42,930,394 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:19,792,807...19,855,784
Ensembl chr20:19,793,083...19,855,827 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:18,831,361...18,855,476
Ensembl chr23:18,833,262...18,833,969 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:117,417,561...117,419,870 JBrowse link
G WDFY1 WD repeat and FYVE domain containing 1 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:109,815,043...109,889,120
Ensembl chr10:109,818,422...109,889,023 		JBrowse link
G ZNRF1 zinc and ring finger 1 involved_in ISO (PMID:28593998) UniProt PMID:28593998 NCBI chr 5:60,568,582...60,590,699 JBrowse link
G ZNRF1 zinc and ring finger 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 5:52,702,740...52,703,165 JBrowse link
positive regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX3X DEAD-box helicase 3 X-linked involved_in ISO (PMID:30341167) UniProt PMID:30341167 NCBI chr  X:38,513,251...38,539,982
Ensembl chr  Y:689,380...706,092 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in IEA Ensembl GO_REF:0000107 Ensembl chr  X:38,512,983...38,525,055 JBrowse link
G LOC119623506 trem-like transcript 4 protein involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:30,907,797...30,923,226
Ensembl chr17:30,915,052...30,923,486 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:19,792,807...19,855,784
Ensembl chr20:19,793,083...19,855,827 		JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:100,778,801...100,804,205
Ensembl chr14:100,778,302...100,798,044 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:124,170,785...124,204,358
Ensembl chr11:124,169,732...124,204,200 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:28,953,805...28,973,055
Ensembl chr  X:28,954,266...28,955,171 		JBrowse link
positive regulation of toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX3X DEAD-box helicase 3 X-linked involved_in ISO (PMID:30341167) UniProt PMID:30341167 NCBI chr  X:38,513,251...38,539,982
Ensembl chr  Y:689,380...706,092 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in IEA Ensembl GO_REF:0000107 Ensembl chr  X:38,512,983...38,525,055 JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:124,170,785...124,204,358
Ensembl chr11:124,169,732...124,204,200 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:28,953,805...28,973,055
Ensembl chr  X:28,954,266...28,955,171 		JBrowse link
positive regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103227720 twinfilin-2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:13,581,102...13,598,830
Ensembl chr22:13,589,034...13,598,752
Ensembl chr22:13,589,034...13,598,752 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:19,792,807...19,855,784
Ensembl chr20:19,793,083...19,855,827 		JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:100,778,801...100,804,205
Ensembl chr14:100,778,302...100,798,044 		JBrowse link
G RTN4 reticulon 4 involved_in ISO (PMID:25917084) UniProt PMID:25917084 NCBI chr14:51,876,697...51,955,788 JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:124,170,785...124,204,358
Ensembl chr11:124,169,732...124,204,200 		JBrowse link
G ZDHHC3 zDHHC palmitoyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:6,391,980...6,452,079
Ensembl chr22:6,403,431...6,452,037 		JBrowse link
positive regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GDI1 GDP dissociation inhibitor 1 involved_in IEA Ensembl GO_REF:0000107
G HSP90B1 heat shock protein 90 beta family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:99,119,268...99,139,988
Ensembl chr11:99,119,224...99,139,722 		JBrowse link
G LRCH4 leucine rich repeats and calponin homology domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:12,627,666...12,639,312
Ensembl chr28:12,627,712...12,638,228 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) UniProt PMID:20728433 NCBI chr 9:89,750,792...89,875,309 JBrowse link
regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD19 CD19 molecule involved_in ISO (PMID:9382888) UniProt PMID:9382888 NCBI chr 5:26,140,703...26,145,447 JBrowse link
G FCMR Fc mu receptor involved_in ISO (PMID:28135254) UniProt PMID:28135254 NCBI chr25:22,435,252...22,453,582
Ensembl chr25:22,435,339...22,447,732 		JBrowse link
G GCSAM germinal center associated signaling and motility involved_in IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr22:68,656,575...68,669,801
Ensembl chr22:68,656,917...68,671,973 		JBrowse link
G GCSAML germinal center associated signaling and motility like involved_in IEA InterPro GO_REF:0000002 NCBI chr25:84,528,022...84,572,887
Ensembl chr25:84,559,054...84,572,624 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:51,919,656...52,057,376
Ensembl chr 8:51,919,808...52,057,959 		JBrowse link
regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD47 CD47 molecule involved_in ISO PMID:21401967 ARUK-UCL PMID:21401967 RGD:13792533 NCBI chr22:72,702,236...72,749,344
Ensembl chr22:72,702,324...72,751,887 		JBrowse link
G CSK C-terminal Src kinase ISO RGD PMID:9325302 RGD:2303720 NCBI chr26:8,667,657...8,688,850
Ensembl chr26:8,667,655...8,688,824 		JBrowse link
G FCGR2A Fc gamma receptor IIa ISO RGD PMID:16482158 PMID:22184119 RGD:11041001 RGD:2293335 NCBI chr20:2,480,710...2,512,429 JBrowse link
G PLSCR1 phospholipid scramblase 1 involved_in ISO PMID:18579528 UniProt PMID:18579528 RGD:2303650 NCBI chr15:44,160,017...44,189,056
Ensembl chr15:44,160,200...44,188,195 		JBrowse link
G PTEN phosphatase and tensin homolog ISO negative regulation RGD PMID:18056380 RGD:2292524 NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146 		JBrowse link
G RABGEF1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (PMID:17341663)
(PMID:15235600) 		MGI PMID:15235600 PMID:17341663 NCBI chr28:2,307,462...2,385,032 JBrowse link
regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRF1 interferon regulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:35,309,058...35,317,765
Ensembl chr23:35,307,772...35,316,763 		JBrowse link
G IRF7 interferon regulatory factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:430,412...433,959
Ensembl chr 1:429,310...432,925 		JBrowse link
regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRF7 interferon regulatory factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:430,412...433,959
Ensembl chr 1:429,310...432,925 		JBrowse link
regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:70,246,081...70,290,851
Ensembl chr14:70,247,168...70,296,463 		JBrowse link
G KCNK13 potassium two pore domain channel subfamily K member 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:67,782,523...67,912,950
Ensembl chr24:67,781,977...67,913,195 		JBrowse link
regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC15A2 solute carrier family 15 member 2 involved_in ISO (PMID:29784761) UniProt PMID:29784761 NCBI chr22:58,916,389...58,966,725
Ensembl chr22:58,913,676...58,966,906 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:124,170,785...124,204,358
Ensembl chr11:124,169,732...124,204,200 		JBrowse link
regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PELI3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chr 1:7,800,430...7,811,226
Ensembl chr 1:7,799,182...7,811,208 		JBrowse link
regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOP53 NOP53 ribosome biogenesis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:41,058,199...41,070,220
Ensembl chr 6:41,057,906...41,071,202 		JBrowse link
regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL10 BCL10 immune signaling adaptor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:48,073,489...48,084,635
Ensembl chr20:48,073,800...48,085,136 		JBrowse link
G CD300A CD300a molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,153,766...47,173,780
Ensembl chr16:47,154,437...47,170,038 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:14752163) MGI PMID:14752163 NCBI chr20:100,582,718...100,618,041 JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 Ensembl chr20:100,583,452...100,618,015 JBrowse link
G LOC103230364 protein tyrosine phosphatase receptor type C involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:30,655,014...30,777,367
Ensembl chr25:30,653,044...30,777,303 		JBrowse link
G MALT1 MALT1 paracaspase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr18:20,984,985...21,064,198
Ensembl chr18:20,985,819...21,054,554 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:19,792,807...19,855,784
Ensembl chr20:19,793,083...19,855,827 		JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:55,167,418...55,258,964
Ensembl chr25:55,167,077...55,279,088 		JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 acts_upstream_of ISO (PMID:28598420) MGI PMID:28598420 NCBI chr11:51,044,269...51,079,210
Ensembl chr11:51,042,095...51,070,939 		JBrowse link
regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLOT2 flotillin 2 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chr16:22,639,403...22,658,311
Ensembl chr16:22,639,381...22,658,194 		JBrowse link
G HCFC2 host cell factor C2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:99,264,638...99,303,923
Ensembl chr11:99,264,674...99,303,732 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776 		JBrowse link
regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:18,546,694...18,591,239
Ensembl chr22:18,546,751...18,589,552 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:100,400,093...100,469,234
Ensembl chr11:100,400,084...100,462,507 		JBrowse link
G FLOT1 flotillin 1 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chr17:41,714,354...41,725,820
Ensembl chr17:41,714,402...41,725,397 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519 		JBrowse link
regulation of toll-like receptor 6 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514) ARUK-UCL PMID:31134514 NCBI chr17:30,965,091...30,999,073
Ensembl chr17:30,994,357...30,999,087 		JBrowse link
regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCRL3 Fc receptor like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,201,252...6,223,913
Ensembl chr20:6,202,200...6,224,479 		JBrowse link
regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chr 2:66,037,224...66,320,860
Ensembl chr 2:66,037,261...66,321,306 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:68,214,875...68,309,336
Ensembl chr21:68,216,201...68,268,669 		JBrowse link
G ESR1 estrogen receptor 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:40,771,238...40,786,008
Ensembl chr20:40,776,816...40,783,717 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:10,158,951...10,268,286
Ensembl chr 8:10,159,421...10,268,323 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:28,953,805...28,973,055
Ensembl chr  X:28,954,266...28,955,171 		JBrowse link
RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLPB ClpB family mitochondrial disaggregase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:63,520,305...63,667,237
Ensembl chr 1:63,515,814...63,667,105 		JBrowse link
G LSM14A LSM14A mRNA processing body assembly factor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:29,211,582...29,266,793
Ensembl chr 6:29,211,785...29,266,981 		JBrowse link
G MAVS mitochondrial antiviral signaling protein acts_upstream_of_or_within ISO (PMID:22745163) MGI PMID:22745163 NCBI chr 2:34,534,433...34,555,406
Ensembl chr 2:34,541,229...34,552,823 		JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:108,192,595...108,210,332
Ensembl chr11:108,192,509...108,213,333 		JBrowse link
G PHB1 prohibitin 1 involved_in ISO (PMID:31522117) UniProt PMID:31522117 NCBI chr16:69,805,968...69,816,792
Ensembl chr16:69,806,923...69,816,754 		JBrowse link
G PHB2 prohibitin 2 involved_in ISO (PMID:31522117) UniProt PMID:31522117 NCBI chr11:6,998,517...7,004,437 JBrowse link
G PHB2 prohibitin 2 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr11:7,001,255...7,004,264 JBrowse link
G RIGI RNA sensor RIG-I involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:47,729,040...47,800,995
Ensembl chr12:47,729,076...47,799,570 		JBrowse link
G RNF135 ring finger protein 135 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:25,677,632...25,700,769
Ensembl chr16:25,678,197...25,700,061 		JBrowse link
G TRIM25 tripartite motif containing 25 NOT|involved_in ISO (PMID:31006531) UniProt PMID:31006531 NCBI chr16:36,496,829...36,522,427
Ensembl chr16:36,496,772...36,524,148 		JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC6A C-type lectin domain containing 6A involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:8,227,590...8,250,857
Ensembl chr11:8,228,381...8,253,159 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in ISO (PMID:19136564) ARUK-UCL PMID:19136564 NCBI chr11:9,989,520...10,007,442
Ensembl chr11:9,995,203...10,006,746 		JBrowse link
G KLRC1 killer cell lectin like receptor C1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:10,286,280...10,294,853
Ensembl chr11:10,286,787...10,293,585 		JBrowse link
G KLRD1 killer cell lectin like receptor D1 involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chr11:10,181,681...10,192,544 JBrowse link
G KLRK1 killer cell lectin like receptor K1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:10,207,066...10,223,922
Ensembl chr11:10,207,211...10,223,899 		JBrowse link
G LOC103218582 NKG2-C type II integral membrane protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:10,266,581...10,277,175 JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:67,209,268...67,394,865
Ensembl chr 5:67,215,459...67,398,990 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:101,254,085...101,374,724
Ensembl chr12:101,260,061...101,349,856 		JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,816,675...30,820,816
Ensembl chr 6:30,816,678...30,820,597 		JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 6:30,816,678...30,820,597 JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,816,675...30,820,816
Ensembl chr 6:30,816,678...30,820,597 		JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 6:30,816,678...30,820,597 JBrowse link
T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:7,258,932...7,435,658
Ensembl chr12:7,256,648...7,312,734 		JBrowse link
G ADA adenosine deaminase acts_upstream_of ISO (PMID:11435465) MGI PMID:11435465 NCBI chr 2:19,167,209...19,200,233 JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:48,073,489...48,084,635
Ensembl chr20:48,073,800...48,085,136 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (PMID:18228248) MGI PMID:18228248 NCBI chr21:109,495,525...109,690,261 JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 Ensembl chr21:109,545,491...109,690,195 JBrowse link
G BTN1A1 butyrophilin subfamily 1 member A1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:45,704,449...45,714,311
Ensembl chr17:45,705,703...45,713,944 		JBrowse link
G BTN2A2 butyrophilin subfamily 2 member A2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:45,857,898...45,869,901
Ensembl chr17:45,744,451...45,868,941 		JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:45,056,116...45,071,076
Ensembl chr11:45,061,046...45,071,544 		JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:37,240,749...37,518,174
Ensembl chr10:37,246,991...37,388,059 		JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (PMID:23793062) MGI PMID:23793062 NCBI chr 5:59,787,069...59,801,615
Ensembl chr 5:59,787,120...59,801,122 		JBrowse link
G CBLB Cbl proto-oncogene B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr22:74,961,831...75,181,307
Ensembl chr22:74,961,859...75,178,548 		JBrowse link
G CD247 CD247 molecule involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr25:61,508,256...61,596,464
Ensembl chr25:61,508,283...61,595,414 		JBrowse link
G CD28 CD28 molecule involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:89,471,710...89,505,152
Ensembl chr10:89,471,730...89,500,387 		JBrowse link
G CD2AP CD2 associated protein acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:24,664,245...24,815,786
Ensembl chr17:24,663,872...24,815,829 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex involved_in
acts_upstream_of_or_within 		IEA Ensembl GO_REF:0000107 NCBI chr 1:109,681,142...109,692,835
Ensembl chr 1:109,681,065...109,692,839 		JBrowse link
G CD8A CD8 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:18,878,013...18,885,183
Ensembl chr14:18,878,622...18,883,885 		JBrowse link
G CD8B CD8 subunit beta involved_in ISO (PMID:17145893) ComplexPortal PMID:17145893 NCBI chr14:18,807,378...18,854,323 JBrowse link
G CLEC2A C-type lectin domain family 2 member A acts_upstream_of_or_within ISO (PMID:16143319) MGI PMID:16143319 NCBI chr11:9,790,411...9,813,839
Ensembl chr11:9,790,671...9,813,543 		JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:4,855,633...4,889,674
Ensembl chr19:4,855,611...4,890,302 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:89,637,176...89,644,436
Ensembl chr10:89,638,314...89,642,344 		JBrowse link
G DENND1B DENN domain containing 1B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr25:31,633,876...31,908,207
Ensembl chr25:31,640,823...31,907,365 		JBrowse link
G EIF2B1 eukaryotic translation initiation factor 2B subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:118,949,674...118,961,913
Ensembl chr11:118,950,409...118,961,687 		JBrowse link
G EIF2B2 eukaryotic translation initiation factor 2B subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:52,217,390...52,224,045
Ensembl chr24:52,217,365...52,227,930 		JBrowse link
G EIF2B3 eukaryotic translation initiation factor 2B subunit gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:87,800,695...87,945,574
Ensembl chr20:87,800,670...87,945,569 		JBrowse link
G EIF2B4 eukaryotic translation initiation factor 2B subunit delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:80,240,874...80,247,555
Ensembl chr14:80,240,449...80,249,521 		JBrowse link
G EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:5,278,759...5,289,422
Ensembl chr15:5,278,749...5,289,030 		JBrowse link
G FCHO1 FCH and mu domain containing endocytic adaptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:16,223,036...16,259,228
Ensembl chr 6:16,238,045...16,265,440 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:79,201,128...79,222,363
Ensembl chr14:79,201,649...79,222,373 		JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:10072494), (PMID:11265635) MGI PMID:10072494 PMID:11265635 NCBI chr  X:46,349,890...46,365,133 JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 Ensembl chr  X:46,346,754...46,356,928 JBrowse link
G FYB1 FYN binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:37,912,771...38,078,727
Ensembl chr 4:37,914,956...38,012,623 		JBrowse link
G FYB2 FYN binding protein 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:76,145,001...76,248,440
Ensembl chr20:76,145,359...76,248,391 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:61,988,265...62,218,756
Ensembl chr13:62,159,874...62,219,672 		JBrowse link
G GATA3 GATA binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:8,101,404...8,122,762
Ensembl chr 9:8,101,432...8,123,064 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr17:39,471,069...39,564,933 JBrowse link
G HRAS HRas proto-oncogene, GTPase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
G ICOSLG inducible T cell costimulator ligand involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:87,974,651...87,986,867
Ensembl chr 2:87,973,786...87,986,639 		JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (PMID:21444916) MGI PMID:21444916 NCBI chr11:63,785,493...63,791,071
Ensembl chr11:63,786,041...63,790,473 		JBrowse link
G ITK IL2 inducible T cell kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:59,575,113...59,650,166
Ensembl chr23:59,575,179...59,650,559 		JBrowse link
G KHDRBS1 KH RNA binding domain containing, signal transduction associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:100,831,307...100,859,609
Ensembl chr20:100,832,461...100,859,630 		JBrowse link
G LAT linker for activation of T cells involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:26,079,387...26,084,823
Ensembl chr 5:26,079,383...26,084,787 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:38614099), (PMID:8943371) UniProt PMID:8943371 PMID:38614099 NCBI chr20:100,582,718...100,618,041 JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 Ensembl chr20:100,583,452...100,618,015 JBrowse link
G LCP2 lymphocyte cytosolic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:72,450,399...72,499,775
Ensembl chr23:72,451,013...72,499,735 		JBrowse link
G LIME1 Lck interacting transmembrane adaptor 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:491,618...494,446
Ensembl chr 2:491,096...493,147 		JBrowse link
G LOC103221987 butyrophilin subfamily 3 member A2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:45,874,447...45,887,984
Ensembl chr17:45,876,877...45,884,925 		JBrowse link
G LOC103224857 selection and upkeep of intraepithelial T-cells protein 1-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:84,722,530...84,934,379 JBrowse link
G LOC103230364 protein tyrosine phosphatase receptor type C involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr25:30,655,014...30,777,367
Ensembl chr25:30,653,044...30,777,303 		JBrowse link
G LOC103245133 butyrophilin-like protein 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr23:82,578,924...82,641,759
Ensembl chr23:82,617,506...82,641,390 		JBrowse link
G LOC103247298 butyrophilin-like protein 9 involved_in IEA TreeGrafter GO_REF:0000118
G MALT1 MALT1 paracaspase involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:20,984,985...21,064,198
Ensembl chr18:20,985,819...21,054,554 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325 		JBrowse link
G MHC-DPB1 major histocompatibility complex, class II, DP beta 1 involved_in ISO (PMID:32341563) UniProt PMID:32341563 NCBI chr17:38,996,329...39,007,097 JBrowse link
G MOG myelin oligodendrocyte glycoprotein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:42,947,174...42,963,046
Ensembl chr17:42,947,279...42,962,159 		JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chr 6:30,800,122...30,812,991
Ensembl chr 6:30,799,204...30,811,141 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:79,044,624...79,077,736
Ensembl chr22:79,044,619...79,055,776 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase acts_upstream_of_or_within ISO (PMID:21444916) MGI PMID:21444916 NCBI chr20:18,953,273...18,966,002
Ensembl chr20:18,953,883...18,961,931 		JBrowse link
G PDE4B phosphodiesterase 4B involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:66,729,561...67,297,729
Ensembl chr20:66,728,664...66,771,691 		JBrowse link
G PDE4D phosphodiesterase 4D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:55,148,012...56,665,684
Ensembl chr 4:55,153,563...55,390,027 		JBrowse link
G PLCG1 phospholipase C gamma 1 acts_upstream_of_or_within ISO (PMID:15728238) MGI PMID:15728238 NCBI chr 2:22,599,547...22,638,394 JBrowse link
G PLCG2 phospholipase C gamma 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:67,209,268...67,394,865
Ensembl chr 5:67,215,459...67,398,990 		JBrowse link
G PRAM1 PML-RARA regulated adaptor molecule 1 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr 6:7,840,582...7,853,429 JBrowse link
G PRKD2 protein kinase D2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,028,214...40,071,523
Ensembl chr 6:40,027,552...40,071,455 		JBrowse link
G PSEN1 presenilin 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr24:50,394,310...50,476,521
Ensembl chr24:50,405,590...50,472,132 		JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (PMID:17698590) MGI PMID:17698590 NCBI chr25:2,862,354...2,888,735
Ensembl chr25:2,862,251...2,877,386 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:19,792,807...19,855,784
Ensembl chr20:19,793,083...19,855,827 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr11:6,977,480...6,994,525
Ensembl chr11:6,984,710...6,994,545 		JBrowse link
G RBCK1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:35,537,387...35,559,628
Ensembl chr 2:35,538,127...35,560,129 		JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:55,167,418...55,258,964
Ensembl chr25:55,167,077...55,279,088 		JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:15,230,206...15,283,253
Ensembl chr12:15,238,124...15,280,689 		JBrowse link
G RFTN1 raftlin, lipid raft linker 1 involved_in ISO (PMID:19414744) UniProt PMID:19414744 NCBI chr15:61,159,573...61,290,342
Ensembl chr15:61,159,930...61,289,965 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in 		IEA
ISO 		(PMID:21469090) Ensembl
UniProt		 PMID:21469090 GO_REF:0000107 NCBI chr 8:84,843,391...84,881,087
Ensembl chr 8:84,843,471...84,881,303 		JBrowse link
G RNF31 ring finger protein 31 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:1,133,589...1,146,020
Ensembl chr24:1,133,723...1,142,943 		JBrowse link
G SHB SH2 domain containing adaptor protein B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:42,520,803...42,669,892
Ensembl chr12:42,520,905...42,669,211 		JBrowse link
G SIVA1 SIVA1 apoptosis inducing factor involved_in ISO (PMID:16491128) HGNC-UCL PMID:16491128 NCBI chr24:82,689,233...82,695,073
Ensembl chr24:82,689,254...82,695,146 		JBrowse link
G SKAP1 src kinase associated phosphoprotein 1 involved_in ISO (PMID:11909961) UniProt PMID:11909961 NCBI chr16:68,539,842...68,851,594 JBrowse link
G SKAP1 src kinase associated phosphoprotein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:68,543,203...68,596,403 JBrowse link
G SLC39A6 solute carrier family 39 member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:44,681,718...44,702,741
Ensembl chr18:44,681,508...44,702,754 		JBrowse link
G SPN sialophorin involved_in ISO PMID:12496963 ARUK-UCL PMID:12496963 RGD:1358565 NCBI chr 5:26,987,810...26,990,214 JBrowse link
G SPPL3 signal peptide peptidase like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:116,125,042...116,267,226
Ensembl chr11:116,124,221...116,267,108 		JBrowse link
G STK11 serine/threonine kinase 11 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:973,033...996,857
Ensembl chr 6:974,144...995,136 		JBrowse link
G STOML2 stomatin like 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:45,513,578...45,516,876
Ensembl chr12:45,513,307...45,517,110 		JBrowse link
G THEMIS thymocyte selection associated involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr13:45,665,494...45,886,672
Ensembl chr13:45,682,663...45,884,856 		JBrowse link
G THEMIS2 thymocyte selection associated family member 2 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:104,909,310...104,933,433
Ensembl chr20:104,908,528...104,926,669 		JBrowse link
G THY1 Thy-1 cell surface antigen involved_in ISO PMID:9285719 UniProt PMID:9285719 RGD:8554466 NCBI chr 1:110,787,213...110,791,536
Ensembl chr 1:110,783,877...110,791,569 		JBrowse link
G TNFRSF21 TNF receptor superfamily member 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:24,981,649...25,053,504
Ensembl chr17:24,981,540...25,055,897 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:28,726,357...28,752,389
Ensembl chr 1:28,734,380...28,747,092 		JBrowse link
G TXK TXK tyrosine kinase involved_in ISO (PMID:10213685) UniProt PMID:10213685 NCBI chr27:2,120,429...2,186,950
Ensembl chr27:2,140,685...2,190,398 		JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chr11:88,810,505...88,842,895 JBrowse link
G VTCN1 V-set domain containing T cell activation inhibitor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:16,511,261...16,583,000
Ensembl chr20:16,511,609...16,571,151 		JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:736,668...893,404
Ensembl chr11:737,590...890,762 		JBrowse link
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 involved_in
acts_upstream_of_or_within 		IEA Ensembl GO_REF:0000107 NCBI chr14:1,403,294...1,430,205
Ensembl chr14:1,404,325...1,431,015 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:95,388,469...95,398,305
Ensembl chr20:95,388,477...95,397,960 		JBrowse link
G ZNF683 zinc finger protein 683 involved_in ISO (PMID:26179882) UniProt PMID:26179882 NCBI chr20:106,336,441...106,411,217 JBrowse link
TIRAP-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIRAP TIR domain containing adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:117,417,561...117,419,870 JBrowse link
toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chr 3:9,353,333...9,357,765 JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in
acts_upstream_of_or_within 		IEA
ISO 		(PMID:10549626) Ensembl
MGI		 PMID:10549626 GO_REF:0000107 NCBI chr  X:128,433,462...128,443,126
Ensembl chr  X:128,433,465...128,443,043 		JBrowse link
G LGALS9 galectin 9 NOT|involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chr16:21,421,034...21,439,583 JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of ISO (PMID:15220916) MGI PMID:15220916 NCBI chr 5:36,492,158...36,531,766
Ensembl chr 5:36,496,414...36,530,499 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:22187460) UniProt PMID:22187460 NCBI chr 9:89,750,792...89,875,309 JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 9:89,783,883...89,875,226 JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:84,843,391...84,881,087
Ensembl chr 8:84,843,471...84,881,303 		JBrowse link
G TLR2 toll like receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:100,239,533...100,565,955
Ensembl chr 7:100,258,441...100,260,795 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr27:46,001,814...46,017,676
Ensembl chr27:46,001,872...46,018,494 		JBrowse link
toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule involved_in ISO (PMID:25158758) UniProt PMID:25158758 NCBI chr22:58,741,534...58,805,417
Ensembl chr22:58,741,525...58,805,366 		JBrowse link
G COLEC12 collectin subfamily member 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:59,701,131...59,884,445
Ensembl chr18:59,699,348...59,884,461 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:59,479,794...59,501,532
Ensembl chr23:59,475,826...59,500,836 		JBrowse link
G LGALS9 galectin 9 involved_in ISO PMID:25158758 UniProt PMID:25158758 RGD:10054077 NCBI chr16:21,421,034...21,439,583 JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:108,163,203...108,176,191
Ensembl chr11:108,163,299...108,176,193 		JBrowse link
G RFTN1 raftlin, lipid raft linker 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr15:61,159,573...61,290,342
Ensembl chr15:61,159,930...61,289,965 		JBrowse link
G RNF170 ring finger protein 170 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:40,852,995...40,896,800
Ensembl chr 8:40,850,552...40,896,887 		JBrowse link
G SCARA3 scavenger receptor class A member 3 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chr 8:25,741,988...25,779,224
Ensembl chr 8:25,742,127...25,782,247 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:28098138) UniProt PMID:28098138 NCBI chr16:4,616,325...4,643,791 JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:4,617,279...4,628,308 JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:4,526,719...4,543,251
Ensembl chr 6:4,527,033...4,529,168 		JBrowse link
G TLR3 toll like receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:131,991,068...132,014,366
Ensembl chr 7:131,991,029...132,016,232 		JBrowse link
G TNF tumor necrosis factor involved_in ISO PMID:25158758 UniProt PMID:25158758 RGD:10054077
G TNIP2 TNFAIP3 interacting protein 2 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr27:46,001,814...46,017,676
Ensembl chr27:46,001,872...46,018,494 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:6,537,198...6,549,457
Ensembl chr 1:6,537,273...6,549,450 		JBrowse link
toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr23:43,264,917...43,266,825
Ensembl chr23:43,264,336...43,266,993 		JBrowse link
G CD180 CD180 molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:63,361,277...63,377,492
Ensembl chr 4:63,359,844...63,377,459 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:93,219,374...93,263,077
Ensembl chr 9:93,219,383...93,262,700 		JBrowse link
G ECSIT ECSIT signaling integrator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:10,430,333...10,440,047
Ensembl chr 6:10,430,446...10,439,830 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chr 3:9,353,333...9,357,765 JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 acts_upstream_of_or_within ISO (PMID:10549626) MGI PMID:10549626 NCBI chr  X:128,433,462...128,443,126
Ensembl chr  X:128,433,465...128,443,043 		JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:46,204,600...46,279,863
Ensembl chr22:46,204,893...46,278,260 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,835,285...42,841,487
Ensembl chr 6:42,831,203...42,840,796 		JBrowse link
G LETMD1 LETM1 domain containing 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:47,258,097...47,270,474
Ensembl chr11:47,258,084...47,270,756 		JBrowse link
G LGALS9 galectin 9 NOT|involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chr16:21,421,034...21,439,583 JBrowse link
G LY96 lymphocyte antigen 96 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:69,591,885...69,629,939
Ensembl chr 8:69,591,941...69,630,274 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:51,919,656...52,057,376
Ensembl chr 8:51,919,808...52,057,959 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:15,284,927...15,360,539
Ensembl chr13:15,284,923...15,360,832 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:1,276,804...1,281,811
Ensembl chr15:1,276,798...1,281,166 		JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO (PMID:29624734) MGI PMID:29624734 NCBI chr16:63,735,411...63,744,365 JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 Ensembl chr16:63,732,508...63,743,971 JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854 		JBrowse link
G NMI N-myc and STAT interactor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:36,702,056...36,722,494
Ensembl chr10:36,702,068...36,715,809 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:108,163,203...108,176,191
Ensembl chr11:108,163,299...108,176,193 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:22187458), (PMID:22187460) UniProt PMID:22187458 PMID:22187460 NCBI chr 9:89,750,792...89,875,309 JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 9:89,783,883...89,875,226 JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:84,843,391...84,881,087
Ensembl chr 8:84,843,471...84,881,303 		JBrowse link
G S100A14 S100 calcium binding protein A14 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:10,188,016...10,190,973
Ensembl chr20:10,188,866...10,190,979 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:28098138) UniProt PMID:28098138 NCBI chr16:4,616,325...4,643,791 JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:4,617,279...4,628,308 JBrowse link
G TBK1 TANK binding kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:60,136,162...60,182,354
Ensembl chr11:60,136,232...60,182,344 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:4,526,719...4,543,251
Ensembl chr 6:4,527,033...4,529,168 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:18,831,361...18,855,476
Ensembl chr23:18,833,262...18,833,969 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:117,417,561...117,419,870 JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within 		IEA
ISO 		(PMID:25549946) Ensembl
TreeGrafter
MGI		 PMID:25549946 GO_REF:0000107 GO_REF:0000118 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
G TMEM126A transmembrane protein 126A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:76,888,688...76,897,883
Ensembl chr 1:76,888,734...76,897,841 		JBrowse link
G TNIP3 TNFAIP3 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:68,416,674...68,519,097
Ensembl chr 7:68,422,328...68,454,143 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:80,735,234...80,872,104
Ensembl chr24:80,789,699...80,866,480 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:28,726,357...28,752,389
Ensembl chr 1:28,734,380...28,747,092 		JBrowse link
G TRIL TLR4 interactor with leucine rich repeats involved_in ISO (PMID:19710467) UniProt PMID:19710467 NCBI chr21:29,416,135...29,421,192 JBrowse link
toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:1,276,804...1,281,811
Ensembl chr15:1,276,798...1,281,166 		JBrowse link
G TIRAP TIR domain containing adaptor protein NOT|involved_in ISO (PMID:12447442) BHF-UCL PMID:12447442 NCBI chr 1:117,417,561...117,419,870 JBrowse link
G TLR5 toll like receptor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:6,418,895...6,440,433
Ensembl chr25:6,437,638...6,440,211 		JBrowse link
toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:59,479,794...59,501,532
Ensembl chr23:59,475,826...59,500,836 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:22187458) UniProt PMID:22187458 NCBI chr 9:89,750,792...89,875,309 JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 9:89,783,883...89,875,226 JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:28098138) UniProt PMID:28098138 NCBI chr16:4,616,325...4,643,791 JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:4,617,279...4,628,308 JBrowse link
G TLR7 toll like receptor 7 involved_in ISO (PMID:14976261)
(PMID:12032557) 		UniProt
GO_Central		 PMID:12032557 PMID:14976261 NCBI chr  X:11,348,520...11,372,132 JBrowse link
G TLR7 toll like receptor 7 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 Ensembl chr  X:11,367,110...11,370,259 JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:6,537,198...6,549,457
Ensembl chr 1:6,537,273...6,549,450 		JBrowse link
toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:1,276,804...1,281,811
Ensembl chr15:1,276,798...1,281,166 		JBrowse link
G TLR7 toll like receptor 7 involved_in ISO (PMID:12032557) GO_Central PMID:12032557 NCBI chr  X:11,348,520...11,372,132 JBrowse link
G TLR7 toll like receptor 7 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr  X:11,367,110...11,370,259 JBrowse link
G TLR8 toll like receptor 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:11,387,933...11,405,056
Ensembl chr  X:11,400,907...11,404,029 		JBrowse link
toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPG5 ectopic P-granules 5 autophagy tethering factor acts_upstream_of_positive_effect IEA Ensembl GO_REF:0000107 NCBI chr18:34,946,778...35,065,449
Ensembl chr18:34,946,796...35,060,595 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:59,479,794...59,501,532
Ensembl chr23:59,475,826...59,500,836 		JBrowse link
G LOC103227720 twinfilin-2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:13,581,102...13,598,830
Ensembl chr22:13,589,034...13,598,752
Ensembl chr22:13,589,034...13,598,752 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:95,792,428...95,877,989
Ensembl chr11:95,792,996...95,878,293 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:22187458), (PMID:22187460) UniProt PMID:22187458 PMID:22187460 NCBI chr 9:89,750,792...89,875,309 JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 9:89,783,883...89,875,226 JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:46,001,814...46,017,676
Ensembl chr27:46,001,872...46,018,494 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:6,537,198...6,549,457
Ensembl chr 1:6,537,273...6,549,450 		JBrowse link
toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP3B1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:72,225,658...72,524,971
Ensembl chr 4:72,225,599...72,524,933 		JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:48,073,489...48,084,635
Ensembl chr20:48,073,800...48,085,136 		JBrowse link
G CD180 CD180 molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:63,361,277...63,377,492
Ensembl chr 4:63,359,844...63,377,459 		JBrowse link
G CD86 CD86 molecule acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chr22:58,741,534...58,805,417
Ensembl chr22:58,741,525...58,805,366 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:8,356,263...8,365,606
Ensembl chr 1:8,356,836...8,364,918 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 ISO RGD PMID:27832756 RGD:34888235 NCBI chr11:61,868,817...61,920,896
Ensembl chr11:61,869,173...61,920,406 		JBrowse link
G LOC103227720 twinfilin-2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr22:13,581,102...13,598,830
Ensembl chr22:13,589,034...13,598,752
Ensembl chr22:13,589,034...13,598,752 		JBrowse link
G LRRC19 leucine rich repeat containing 19 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107
G LY96 lymphocyte antigen 96 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:69,591,885...69,629,939
Ensembl chr 8:69,591,941...69,630,274 		JBrowse link
G MAPKAPK2 MAPK activated protein kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:22,632,180...22,681,250
Ensembl chr25:22,629,729...22,681,373 		JBrowse link
G MAPKAPK3 MAPK activated protein kinase 3 involved_in ISO (PMID:17906627) UniProt PMID:17906627 NCBI chr22:11,998,774...12,036,477 JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:79,044,624...79,077,736
Ensembl chr22:79,044,619...79,055,776 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:67,209,268...67,394,865
Ensembl chr 5:67,215,459...67,398,990 		JBrowse link
G RPS6KA3 ribosomal protein S6 kinase A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:18,614,664...18,730,591
Ensembl chr  X:18,620,159...18,730,581 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:4,526,719...4,543,251
Ensembl chr 6:4,527,033...4,529,168 		JBrowse link
G TIFAB TIFA inhibitor acts_upstream_of_negative_effect ISO (PMID:26458771) MGI PMID:26458771 NCBI chr23:38,228,904...38,232,892 JBrowse link
G TIFAB TIFA inhibitor acts_upstream_of_negative_effect IEA Ensembl GO_REF:0000107 Ensembl chr23:38,229,485...38,232,210 JBrowse link
G TLR1 toll like receptor 1 involved_in ISO
IEA 		RGD
TreeGrafter
Ensembl
InterPro		 PMID:16973131 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1643119 NCBI chr27:11,482,307...11,490,847
Ensembl chr27:11,488,294...11,490,654 		JBrowse link
G TLR10 toll like receptor 10 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr27:11,486,273...11,515,841
Ensembl chr27:11,512,239...11,514,671 		JBrowse link
G TLR2 toll like receptor 2 involved_in ISO
IEA 		RGD
Ensembl
TreeGrafter
UniProt
InterPro		 PMID:16973131 PMID:18353287 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 RGD:1643119 RGD:5684896 NCBI chr 7:100,239,533...100,565,955
Ensembl chr 7:100,258,441...100,260,795 		JBrowse link
G TLR3 toll like receptor 3 involved_in ISO
IEA 		RGD
TreeGrafter
Ensembl		 PMID:16973131 GO_REF:0000107 GO_REF:0000118 RGD:1643119 NCBI chr 7:131,991,068...132,014,366
Ensembl chr 7:131,991,029...132,016,232 		JBrowse link
G TLR4 toll like receptor 4 involved_in ISO
IEA 		RGD
TreeGrafter
Ensembl
InterPro		 PMID:16973131 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1643119 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
G TLR5 toll like receptor 5 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr25:6,418,895...6,440,433
Ensembl chr25:6,437,638...6,440,211 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISO
IEA 		RGD
TreeGrafter
InterPro		 PMID:16973131 PMID:18353287 GO_REF:0000002 GO_REF:0000118 RGD:1643119 RGD:5684896 NCBI chr27:11,439,288...11,461,580
Ensembl chr27:11,459,181...11,461,571 		JBrowse link
G TLR7 toll like receptor 7 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr  X:11,367,110...11,370,259 JBrowse link
G TLR8 toll like receptor 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:11,387,933...11,405,056
Ensembl chr  X:11,400,907...11,404,029 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:80,735,234...80,872,104
Ensembl chr24:80,789,699...80,866,480 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in
acts_upstream_of_or_within 		IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:6,537,198...6,549,457
Ensembl chr 1:6,537,273...6,549,450 		JBrowse link
toll-like receptor TLR1:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:28098138) UniProt PMID:28098138 NCBI chr16:4,616,325...4,643,791 JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:4,617,279...4,628,308 JBrowse link
toll-like receptor TLR6:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:1,276,804...1,281,811
Ensembl chr15:1,276,798...1,281,166 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516 		JBrowse link
G TLR2 toll like receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:100,239,533...100,565,955
Ensembl chr 7:100,258,441...100,260,795 		JBrowse link
G TLR6 toll like receptor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:11,439,288...11,461,580
Ensembl chr27:11,459,181...11,461,571 		JBrowse link
TRAM-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCE protein kinase C epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:61,022,903...61,570,390
Ensembl chr14:61,026,017...61,242,343 		JBrowse link
G RAB11FIP2 RAB11 family interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:110,805,236...110,846,691
Ensembl chr 9:110,805,022...110,846,830 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:18,831,361...18,855,476
Ensembl chr23:18,833,262...18,833,969 		JBrowse link
TRIF-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD274 CD274 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:74,038,844...74,060,662
Ensembl chr12:74,041,767...74,056,806 		JBrowse link
G CD300LF CD300 molecule like family member f involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:46,944,701...46,963,559
Ensembl chr16:46,944,921...46,962,770 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,835,285...42,841,487
Ensembl chr 6:42,831,203...42,840,796 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:4,526,719...4,543,251
Ensembl chr 6:4,527,033...4,529,168 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr23:18,831,361...18,855,476
Ensembl chr23:18,833,262...18,833,969 		JBrowse link
G TLR4 toll like receptor 4 involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
G TLR6 toll like receptor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:11,439,288...11,461,580
Ensembl chr27:11,459,181...11,461,571 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19706
    immune system process 2678
      activation of immune response 580
        immune response-activating signaling pathway 512
          immune response-activating cell surface receptor signaling pathway + 300
          innate immune response-activating signaling pathway + 309
Path 2
Term Annotations click to browse term
  biological_process 19706
    biological regulation 12159
      regulation of biological process 11759
        positive regulation of biological process 6675
          positive regulation of response to stimulus 2535
            positive regulation of immune response 789
              activation of immune response 580
                immune response-activating signaling pathway 512
                  immune response-activating cell surface receptor signaling pathway + 300
                  innate immune response-activating signaling pathway + 309
paths to the root