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ONTOLOGY REPORT - ANNOTATIONS

Term:immune response-activating signaling pathway
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Accession:GO:0002757 term browser browse the term
Definition:The series of molecular signals generated by a ligand binding to its receptor that lead to the activation or perpetuation of an immune response.
Synonyms:exact_synonym: immune response-activating signal transduction


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immune response-activating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:4,972,369...4,984,218
Ensembl chr15:4,972,956...4,980,371 		JBrowse link
antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCAR1 BCAR1 scaffold protein, Cas family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:75,463,906...75,499,557
Ensembl chr 5:75,463,926...75,512,476 		JBrowse link
G CD19 CD19 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,419,092...18,425,524
Ensembl chr 6:18,418,241...18,425,400 		JBrowse link
G LAX1 lymphocyte transmembrane adaptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15843560) TreeGrafter
MGI		 PMID:15843560 GO_REF:0000118 NCBI chr38:429,062...438,069
Ensembl chr38:429,528...436,696 		JBrowse link
G SH2B2 SH2B adaptor protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:7,795,756...7,820,010
Ensembl chr 6:7,795,373...7,819,843 		JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:107,423,388...107,426,464
Ensembl chr 1:107,422,424...107,426,464 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:8,147,160...8,154,401
Ensembl chr33:8,073,840...8,154,561 		JBrowse link
B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11120811), (PMID:19228876) Ensembl
MGI		 PMID:11120811 PMID:19228876 GO_REF:0000107 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307 		JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:75,463,906...75,499,557
Ensembl chr 5:75,463,926...75,512,476 		JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658 		JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:26,336,253...26,357,494
Ensembl chr25:26,336,892...26,358,015 		JBrowse link
G BLNK B cell linker involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:9,622,438...9,700,335
Ensembl chr28:9,622,752...9,732,639 		JBrowse link
G BMX BMX non-receptor tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:11,742,805...11,795,437
Ensembl chr  X:11,738,365...11,795,436 		JBrowse link
G BTK Bruton tyrosine kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:75,270,952...75,302,663
Ensembl chr  X:75,270,979...75,302,562 		JBrowse link
G CD19 CD19 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9254656) Ensembl
MGI
TreeGrafter		 PMID:9254656 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:18,419,092...18,425,524
Ensembl chr 6:18,418,241...18,425,400 		JBrowse link
G CD38 CD38 molecule involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr 3:64,529,129...64,577,755
Ensembl chr 3:64,529,721...64,578,099 		JBrowse link
G CD79A CD79a molecule involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:1373499), (PMID:8626447) InterPro
MGI
TreeGrafter
GO_Central
Ensembl		 PMID:1373499 PMID:8626447 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:112,411,281...112,414,827
Ensembl chr 1:112,411,281...112,427,381 		JBrowse link
G CD79B CD79b molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1373499), (PMID:8626447) InterPro
MGI
TreeGrafter		 PMID:1373499 PMID:8626447 GO_REF:0000002 GO_REF:0000118 NCBI chr 9:11,834,230...11,844,946
Ensembl chr 9:11,842,190...11,844,843 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874 		JBrowse link
G FCRL5 Fc receptor like 5 acts_upstream_of ISO (PMID:23509253) MGI PMID:23509253 NCBI chr 7:40,685,554...40,719,195
Ensembl chr 7:40,696,448...40,716,314 		JBrowse link
G GRB2 growth factor receptor bound protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:5,108,128...5,182,091
Ensembl chr 9:5,117,164...5,180,296 		JBrowse link
G ITK IL2 inducible T cell kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:52,902,886...52,966,465
Ensembl chr 4:52,902,871...52,966,542 		JBrowse link
G KLHL6 kelch like family member 6 involved_in IEA InterPro GO_REF:0000002 NCBI chr34:16,443,282...16,556,991
Ensembl chr34:16,446,944...16,504,549 		JBrowse link
G LAT2 linker for activation of T cells family member 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:6,160,939...6,175,271
Ensembl chr 6:6,161,542...6,173,294 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7499277) TreeGrafter
MGI		 PMID:7499277 GO_REF:0000118 NCBI chr 2:68,940,816...68,964,585
Ensembl chr 2:68,941,249...68,964,567 		JBrowse link
G LIME1 Lck interacting transmembrane adaptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16249387) InterPro
MGI
TreeGrafter		 PMID:16249387 GO_REF:0000002 GO_REF:0000118 NCBI chr24:47,269,922...47,272,288 JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7499277)
(PMID:23509253)		 Ensembl
MGI		 PMID:7499277 PMID:23509253 GO_REF:0000107 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9254656) Ensembl
MGI		 PMID:9254656 GO_REF:0000107 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998 		JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISO (MGI:3829850|PMID:18955699) UniProt PMID:18955699 MGI:3829850 NCBI chr 3:19,778,997...19,948,203
Ensembl chr 3:19,779,007...19,943,852 		JBrowse link
G MNDA myeloid cell nuclear differentiation antigen involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr38:22,921,729...22,934,276
Ensembl chr38:22,921,732...22,934,286 		JBrowse link
G MS4A1 membrane spanning 4-domains A1 involved_in ISO (PMID:18474602) UniProt PMID:18474602 NCBI chr21:50,722,142...50,734,934
Ensembl chr21:50,722,041...50,733,704 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439 		JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15143214) TreeGrafter
MGI		 PMID:15143214 GO_REF:0000118 NCBI chr10:23,008,084...23,047,227
Ensembl chr10:23,008,393...23,045,565 		JBrowse link
G NFATC2 nuclear factor of activated T cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:37,606,977...37,734,813
Ensembl chr24:37,609,561...37,771,132 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:23,948,598...24,040,704
Ensembl chr32:23,942,954...24,040,703 		JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:14,100,203...14,103,453
Ensembl chr 8:14,100,671...14,103,433 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:8,147,160...8,154,401
Ensembl chr33:8,073,840...8,154,561 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049 		JBrowse link
G PLEKHA1 pleckstrin homology domain containing A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:32,025,791...32,081,824
Ensembl chr28:32,026,350...32,081,835 		JBrowse link
G PRKCB protein kinase C beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:21,742,970...22,064,360
Ensembl chr 6:21,742,973...22,065,185 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23509253)
(PMID:9254656)		 Ensembl
MGI		 PMID:9254656 PMID:23509253 GO_REF:0000107 NCBI chr27:38,084,976...38,101,552
Ensembl chr27:38,084,980...38,101,937 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9254656)
(PMID:7499277)		 Ensembl
MGI		 PMID:7499277 PMID:9254656 GO_REF:0000107 NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124 		JBrowse link
G RFTN1 raftlin, lipid raft linker 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:26,272,103...26,472,610
Ensembl chr23:26,282,392...26,472,536 		JBrowse link
G RPS19 ribosomal protein S19 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 1:112,418,800...112,427,445
Ensembl chr 1:112,411,281...112,427,381 		JBrowse link
G SH2B2 SH2B adaptor protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10872802) Ensembl
MGI		 PMID:10872802 GO_REF:0000107 NCBI chr 6:7,795,756...7,820,010
Ensembl chr 6:7,795,373...7,819,843 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:31,007,940...31,181,569
Ensembl chr17:31,009,257...31,142,063 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7499277), (PMID:8626447) Ensembl
MGI
TreeGrafter		 PMID:7499277 PMID:8626447 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583 		JBrowse link
G TEC tec protein tyrosine kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr13:43,978,964...44,111,256
Ensembl chr13:43,978,573...44,062,795 		JBrowse link
G TXK TXK tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:43,911,881...43,977,499
Ensembl chr13:43,914,534...43,976,655 		JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:43,663,787...44,002,362
Ensembl chr 6:43,559,985...44,000,811 		JBrowse link
CARD8 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC119876002 caspase recruitment domain-containing protein 8-like involved_in IEA Ensembl GO_REF:0000107
G LOC491519 caspase recruitment domain family, member 8 involved_in ISO (PMID:31525884), (PMID:33053349), (PMID:33420028), (PMID:33420033) UniProt PMID:31525884 PMID:33053349 PMID:33420028 PMID:33420033 NCBI chr 1:107,994,215...108,025,875 JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:35,790,505...35,792,967 JBrowse link
G CLEC7A C-type lectin domain containing 7A acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chr27:35,852,685...35,885,673
Ensembl chr27:35,853,099...36,007,157 		JBrowse link
G FCN2 ficolin 2 involved_in ISO (PMID:21037097) UniProt PMID:21037097 NCBI chr 9:50,868,942...50,876,001
Ensembl chr 9:50,868,973...50,875,792 		JBrowse link
G FFAR2 free fatty acid receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:117,197,535...117,201,613
Ensembl chr 1:117,198,289...117,199,284 		JBrowse link
G LBP lipopolysaccharide binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:26,810,369...26,833,515
Ensembl chr24:26,809,843...26,833,434 		JBrowse link
G MBL1 mannose binding lectin 1 involved_in ISO (PMID:22966085) ComplexPortal PMID:22966085 NCBI chr 4:29,419,886...29,424,377 JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241 		JBrowse link
cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CGAS cyclic GMP-AMP synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:35,511,920...35,528,759
Ensembl chr12:35,512,860...35,528,596 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:34,783,947...34,792,204
Ensembl chr 2:34,784,232...34,789,072 		JBrowse link
complement component C5a signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3AR1 complement C3a receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chr27:37,431,745...37,439,858
Ensembl chr27:37,433,792...37,435,246 		JBrowse link
G C5AR1 complement C5a receptor 1 involved_in IEA Ensembl
GOC		 GO_REF:0000107 GO_REF:0000108 NCBI chr 1:108,659,637...108,704,217
Ensembl chr 1:108,659,637...108,675,401 		JBrowse link
G C5AR2 complement C5a receptor 2 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:108,644,195...108,652,628
Ensembl chr 1:108,644,945...108,645,958 		JBrowse link
G LTB4R leukotriene B4 receptor involved_in IEA GOC GO_REF:0000108 NCBI chr 8:4,282,924...4,286,869
Ensembl chr 8:4,285,323...4,286,534 		JBrowse link
complement receptor mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761 		JBrowse link
G C3AR1 complement C3a receptor 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr27:37,431,745...37,439,858
Ensembl chr27:37,433,792...37,435,246 		JBrowse link
G C5AR1 complement C5a receptor 1 involved_in IEA
IBA		 GOC
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000108 GO_REF:0000118 NCBI chr 1:108,659,637...108,704,217
Ensembl chr 1:108,659,637...108,675,401 		JBrowse link
G C5AR2 complement C5a receptor 2 involved_in IEA GOC
TreeGrafter		 GO_REF:0000108 GO_REF:0000118 NCBI chr 1:108,644,195...108,652,628
Ensembl chr 1:108,644,945...108,645,958 		JBrowse link
G CMKLR1 chemerin chemokine-like receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr26:18,487,700...18,539,678
Ensembl chr26:18,532,479...18,533,576 		JBrowse link
G CMKLR2 chemerin chemokine-like receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr37:14,725,573...14,776,009
Ensembl chr37:14,726,766...14,727,833 		JBrowse link
G FPR formyl peptide receptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:105,343,096...105,353,563
Ensembl chr 1:105,344,463...105,372,070 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:22,495,001...22,556,264
Ensembl chr35:22,495,073...22,554,105 		JBrowse link
G GPR33 G protein-coupled receptor 33 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:10,718,470...10,720,029
Ensembl chr 8:10,719,010...10,720,029 		JBrowse link
G ITGAM integrin subunit alpha M involved_in ISO (MGI:6189359|PMID:22632727) ARUK-UCL PMID:22632727 MGI:6189359 NCBI chr 6:16,944,062...16,996,525
Ensembl chr 6:16,808,971...16,996,286 		JBrowse link
G LOC490269 complement receptor type 2 involved_in ISO (PMID:16360013), (PMID:22962438) ARUK-UCL PMID:16360013 PMID:22962438 NCBI chr 7:6,456,238...6,480,672 JBrowse link
G LTB4R leukotriene B4 receptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:4,282,924...4,286,869
Ensembl chr 8:4,285,323...4,286,534 		JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:55,426,632...55,431,916
Ensembl chr18:55,429,308...55,430,510 		JBrowse link
cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALPK1 alpha kinase 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr32:32,135,110...32,270,732
Ensembl chr32:32,136,738...32,267,264 		JBrowse link
G BECN1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:35,511,920...35,528,759
Ensembl chr12:35,512,860...35,528,596 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,787,470...20,795,593
Ensembl chr 9:20,787,541...20,795,361 		JBrowse link
G IPO5 importin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:48,126,053...48,182,897
Ensembl chr22:48,136,242...48,180,495 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:106,875,016...106,879,065
Ensembl chr 1:106,875,118...106,879,065 		JBrowse link
G IRF7 interferon regulatory factor 7 involved_in ISO (PMID:21931555) UniProt PMID:21931555
G LOC119877912 beclin-1 involved_in IEA Ensembl GO_REF:0000107
G LOC119878870 TRAF3-interacting JNK-activating modulator-like involved_in IEA Ensembl GO_REF:0000107
G LOC119878872 TRAF3-interacting JNK-activating modulator-like involved_in IEA Ensembl GO_REF:0000107
G MAVS mitochondrial antiviral signaling protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:17,510,209...17,529,286
Ensembl chr24:17,512,761...17,523,807 		JBrowse link
G RIGI RNA sensor RIG-I involved_in ISO (PMID:19576794) UniProt PMID:19576794 NCBI chr11:49,764,252...49,799,626
Ensembl chr11:49,764,267...49,799,527 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:34,783,947...34,792,204
Ensembl chr 2:34,784,232...34,789,072 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:7,169,664...7,208,890
Ensembl chr10:7,168,007...7,208,899 		JBrowse link
G TIFA TRAF interacting protein with forkhead associated domain involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr32:32,125,870...32,135,159
Ensembl chr32:32,126,634...32,127,191 		JBrowse link
G TRAF3IP3 TRAF3 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:8,421,163...8,444,399
Ensembl chr 7:8,421,788...8,444,397 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:31,674,242...31,689,160
Ensembl chr18:31,675,391...31,688,641 		JBrowse link
G TRIM25 tripartite motif containing 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:31,703,628...31,725,674
Ensembl chr 9:31,707,034...31,725,762 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in ISO (PMID:22607805) UniProt PMID:22607805 NCBI chr 9:45,506,830...45,562,081
Ensembl chr 9:45,507,282...45,562,086 		JBrowse link
endolysosomal toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WASHC4 WASH complex subunit 4 acts_upstream_of_or_within ISO (PMID:33749590) MGI PMID:33749590 NCBI chr10:33,245,944...33,300,142
Ensembl chr10:33,248,098...33,300,057 		JBrowse link
Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER1G Fc epsilon receptor Ig involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14764707) TreeGrafter
MGI		 PMID:14764707 GO_REF:0000118 NCBI chr38:21,267,841...21,271,036
Ensembl chr38:21,268,001...21,270,940 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507 		JBrowse link
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYO1G myosin IG involved_in IEA Ensembl GO_REF:0000107
immune response-activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG6 BAG cochaperone 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,126,730...1,141,978
Ensembl chr12:1,126,732...1,137,896 		JBrowse link
G NCR3 natural cytotoxicity triggering receptor 3 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr12:1,086,698...1,104,268
Ensembl chr12:1,086,841...1,089,481 		JBrowse link
G NCR3 natural cytotoxicity triggering receptor 3 involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
innate immune response activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC484309 leukocyte immunoglobulin-like receptor subfamily A member 6 involved_in ISO (PMID:27572839) UniProt PMID:27572839 NCBI chr 1:102,995,743...103,014,085 JBrowse link
innate immune response-activating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TLR4 toll like receptor 4 ISO RGD PMID:19226379 RGD:2312509 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFIH1 interferon induced with helicase C domain 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr36:7,668,925...7,727,040
Ensembl chr36:7,649,727...8,261,048 		JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:10,404,548...10,423,039
Ensembl chr26:10,404,414...10,423,039 		JBrowse link
MyD88-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRFIP2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chr23:6,939,476...7,047,721
Ensembl chr23:6,940,318...7,047,610 		JBrowse link
MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAPK1 death associated protein kinase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:72,278,939...72,448,907
Ensembl chr 1:72,280,103...72,447,822 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) BHF-UCL PMID:16148103 NCBI chr37:7,010,421...7,025,912 JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12872135)
(PMID:12719478)
(PMID:14764662)		 InterPro
MGI
Ensembl		 PMID:12719478 PMID:12872135 PMID:14764662 GO_REF:0000002 GO_REF:0000107 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534 		JBrowse link
G REG3A regenerating islet-derived 3 alpha involved_in ISO (MGI:3760234|PMID:17635956) UniProt PMID:17635956 MGI:3760234 NCBI chr17:44,859,106...44,864,793
Ensembl chr17:44,859,137...44,861,899 		JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241 		JBrowse link
G TLR4 toll like receptor 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISO (MGI:4438693|PMID:20037584)
(PMID:20037584)		 ARUK-UCL
ComplexPortal		 PMID:20037584 MGI:4438693 NCBI chr 3:73,504,357...73,523,964
Ensembl chr 3:73,520,706...73,523,099 		JBrowse link
G TLR9 toll like receptor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114 		JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 involved_in ISO (MGI:5305352|PMID:22011580) UniProt PMID:22011580 MGI:5305352 NCBI chr 4:58,150,734...58,200,158
Ensembl chr 4:58,149,882...58,199,644 		JBrowse link
MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRFIP2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chr23:6,939,476...7,047,721
Ensembl chr23:6,940,318...7,047,610 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO (PMID:12872135)
(PMID:12855817)		 MGI PMID:12855817 PMID:12872135 NCBI chr20:54,948,237...54,961,996
Ensembl chr20:54,959,525...54,961,780 		JBrowse link
G TNIP3 TNFAIP3 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:18,857,719...18,960,760
Ensembl chr19:18,853,168...18,960,760 		JBrowse link
negative regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC488622 myeloid cell nuclear differentiation antigen involved_in ISO (PMID:30104205) UniProt PMID:30104205 NCBI chr38:22,874,345...22,892,362 JBrowse link
G TRIM11 tripartite motif containing 11 involved_in ISO (PMID:27498865) UniProt PMID:27498865 NCBI chr14:640,375...647,427 JBrowse link
G TRIM17 tripartite motif containing 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:633,767...639,543
Ensembl chr14:634,060...647,431 		JBrowse link
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD22 CD22 molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:117,261,730...117,285,775
Ensembl chr 1:117,261,740...117,284,818 		JBrowse link
G CD300A CD300a molecule involved_in ISO (PMID:21482706) UniProt PMID:21482706 NCBI chr 9:5,952,428...5,976,328 JBrowse link
G FCGR2B Fc fragment of IgG receptor IIb involved_in ISO (PMID:24169826) ARUK-UCL PMID:24169826 NCBI chr38:20,980,777...20,994,403 JBrowse link
G FCRL3 Fc receptor like 3 involved_in ISO (PMID:19843936) UniProt PMID:19843936 NCBI chr 7:40,599,319...40,625,939 JBrowse link
G FCRL5 Fc receptor like 5 acts_upstream_of_or_within ISO (PMID:23509253) MGI PMID:23509253 NCBI chr 7:40,685,554...40,719,195
Ensembl chr 7:40,696,448...40,716,314 		JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,273,169...32,275,915
Ensembl chr 5:32,273,173...32,275,580 		JBrowse link
G LPXN leupaxin involved_in ISO (PMID:17640867)
(MGI:3722965|PMID:17640867)		 UniProt PMID:17640867 MGI:3722965 NCBI chr18:37,809,612...37,847,958
Ensembl chr18:37,810,007...37,847,306 		JBrowse link
G MIR34A microRNA mir-34a involved_in ISO (PMID:30111844) ARUK-UCL PMID:30111844 NCBI chr 5:62,485,832...62,485,897
Ensembl chr 5:62,485,832...62,485,897 		JBrowse link
G PLCL2 phospholipase C like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14517301) Ensembl
MGI		 PMID:14517301 GO_REF:0000107 NCBI chr23:25,814,392...25,999,666
Ensembl chr23:25,814,862...25,999,749 		JBrowse link
negative regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G AURKB aurora kinase B involved_in ISO (PMID:33542149) UniProt PMID:33542149 NCBI chr 5:33,014,098...33,028,951
Ensembl chr 5:33,014,102...33,033,948 		JBrowse link
G BANF1 BAF nuclear assembly factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,269,817...51,271,484
Ensembl chr18:51,269,815...51,271,690 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:35,511,920...35,528,759
Ensembl chr12:35,512,860...35,528,596 		JBrowse link
G LOC481473 immunity-related GTPase family M protein involved_in ISO (PMID:32715615) UniProt PMID:32715615 NCBI chr11:793,416...795,373
Ensembl chr11:793,424...794,617 		JBrowse link
G LYPLAL1 lysophospholipase like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:14,100,818...14,137,292
Ensembl chr38:14,100,698...14,268,481 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127 		JBrowse link
G PCBP2 poly(rC) binding protein 2 involved_in ISO (PMID:35322803) UniProt PMID:35322803 NCBI chr27:1,736,264...1,759,416 JBrowse link
G PPP6C protein phosphatase 6 catalytic subunit involved_in ISO (PMID:32474700) UniProt PMID:32474700 NCBI chr 9:57,884,035...57,921,080
Ensembl chr 5:43,094,942...43,095,395
Ensembl chr 9:43,094,942...43,095,395 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:24,904...243,926
Ensembl chr29:35,007...243,895 		JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:40,624,845...40,626,840
Ensembl chr20:40,624,891...40,626,906 		JBrowse link
G ZDHHC18 zinc finger DHHC-type palmitoyltransferase 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:73,274,186...73,297,375
Ensembl chr 2:73,276,876...73,296,976 		JBrowse link
negative regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITCH itchy E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:23,476,619...23,630,574
Ensembl chr24:23,476,736...23,627,469 		JBrowse link
G TARBP2 TARBP2 subunit of RISC loading complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:1,715,157...1,720,050
Ensembl chr27:1,715,158...1,726,885 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:40,845,532...40,939,172
Ensembl chr14:40,845,564...40,944,438 		JBrowse link
G TSPAN6 tetraspanin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:74,499,684...74,510,079
Ensembl chr  X:74,499,686...74,505,683 		JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,123,577...33,166,831
Ensembl chr20:33,130,723...33,166,792 		JBrowse link
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QBP complement C1q binding protein involved_in ISO (PMID:19164550) UniProt PMID:19164550 NCBI chr 5:31,354,665...31,359,672
Ensembl chr 5:31,354,723...31,359,469 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,787,470...20,795,593
Ensembl chr 9:20,787,541...20,795,361 		JBrowse link
G RIOK3 RIO kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:64,835,810...64,860,464
Ensembl chr 7:64,837,233...64,860,393 		JBrowse link
G TKFC triokinase and FMN cyclase involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:55,051,068...55,064,571
Ensembl chr18:55,051,097...55,064,526 		JBrowse link
negative regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300A CD300a molecule involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chr 9:5,952,428...5,976,328 JBrowse link
G CD300LF CD300 molecule like family member f involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chr 9:5,700,915...5,714,868 JBrowse link
negative regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SARM1 sterile alpha and TIR motif containing 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:42,620,878...42,639,662
Ensembl chr 9:42,622,538...42,639,590 		JBrowse link
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD17A abhydrolase domain containing 17A, depalmitoylase involved_in ISO (PMID:38092000) UniProt PMID:38092000 NCBI chr20:57,083,381...57,092,021
Ensembl chr20:57,086,800...57,092,001 		JBrowse link
G CPTP ceramide-1-phosphate transfer protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:56,498,163...56,501,918
Ensembl chr 5:56,498,207...56,500,845 		JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 involved_in ISO (MGI:6787653|PMID:34615873) UniProt PMID:34615873 MGI:6787653 NCBI chr 4:59,435,530...59,485,591
Ensembl chr 4:59,435,764...59,483,475 		JBrowse link
G FBXL2 F-box and leucine rich repeat protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:3,498,253...3,606,016
Ensembl chr23:3,498,979...3,607,093 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:11,292,219...11,296,851
Ensembl chr 5:11,292,262...11,296,797 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 involved_in ISO (PMID:36586411) UniProt PMID:36586411 NCBI chr  X:92,405,946...92,444,527
Ensembl chr  X:92,407,950...92,444,765 		JBrowse link
G LOC119873859 heat shock cognate 71 kDa protein-like involved_in IEA Ensembl GO_REF:0000107
G LOC119876002 caspase recruitment domain-containing protein 8-like involved_in IEA Ensembl GO_REF:0000107
G LOC481473 immunity-related GTPase family M protein involved_in ISO (PMID:30612879) UniProt PMID:30612879 NCBI chr11:793,416...795,373
Ensembl chr11:793,424...794,617 		JBrowse link
G LOC491519 caspase recruitment domain family, member 8 involved_in ISO (PMID:24517500) UniProt PMID:24517500 NCBI chr 1:107,994,215...108,025,875 JBrowse link
G LOC606863 immunity-related GTPase family M protein-like involved_in ISO (MGI:6282153|PMID:30612879) UniProt PMID:30612879 MGI:6282153 NCBI chr11:506,981...523,338
Ensembl chr11:509,636...510,829 		JBrowse link
G LOC607182 heat shock cognate 71 kDa protein-like involved_in IEA Ensembl GO_REF:0000107
G MEFV MEFV innate immunity regulator, pyrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:37,964,776...37,984,830
Ensembl chr 6:37,970,608...37,983,737 		JBrowse link
G NLRC3 NLR family CARD domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:37,668,654...37,707,387
Ensembl chr 6:37,647,976...37,703,190 		JBrowse link
G SIRT2 sirtuin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23502856) Ensembl
MGI		 PMID:23502856 GO_REF:0000107 NCBI chr 1:114,224,922...114,235,041
Ensembl chr 1:114,224,900...114,234,583 		JBrowse link
G TREML1 triggering receptor expressed on myeloid cells like 1 acts_upstream_of_or_within ISO (PMID:32514138) ARUK-UCL PMID:32514138 NCBI chr12:9,915,692...9,928,322
Ensembl chr12:9,915,677...9,928,174 		JBrowse link
G TRIM22 tripartite motif containing 22 involved_in ISO (MGI:4868339|PMID:21048113) UniProt PMID:21048113 MGI:4868339 NCBI chr21:28,677,196...28,696,413
Ensembl chr21:28,682,973...28,695,185 		JBrowse link
G ZDHHC12 zinc finger DHHC-type palmitoyltransferase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:54,877,188...54,880,579
Ensembl chr 9:54,877,110...54,880,553 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:30,247,432...30,262,992
Ensembl chr 1:30,251,059...30,261,001 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERBIN erbb2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:51,613,344...51,730,868
Ensembl chr 2:51,613,230...51,729,021 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:30,247,432...30,262,992
Ensembl chr 1:30,251,059...30,261,001 		JBrowse link
G ZNRF4 zinc and ring finger 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:54,498,150...54,499,662
Ensembl chr20:54,493,227...54,499,675 		JBrowse link
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QBP complement C1q binding protein involved_in ISO (PMID:19164550) UniProt PMID:19164550 NCBI chr 5:31,354,665...31,359,672
Ensembl chr 5:31,354,723...31,359,469 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:20,787,470...20,795,593
Ensembl chr 9:20,787,541...20,795,361 		JBrowse link
G GPATCH3 G-patch domain containing 3 involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:73,243,178...73,250,926
Ensembl chr 2:73,243,222...73,250,403 		JBrowse link
G NLRX1 NLR family member X1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21703540) Ensembl
MGI		 PMID:21703540 GO_REF:0000107 NCBI chr 5:14,692,621...14,705,214
Ensembl chr 5:14,564,935...14,705,257 		JBrowse link
G NPLOC4 NPL4 homolog, ubiquitin recognition factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:538,087...604,898
Ensembl chr 9:537,840...603,480 		JBrowse link
G RNF125 ring finger protein 125 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:57,570,779...57,607,485
Ensembl chr 7:57,574,738...57,608,017 		JBrowse link
G SEC14L1 SEC14 like lipid binding 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:3,683,328...3,740,271
Ensembl chr 9:3,659,451...3,739,213 		JBrowse link
G UFD1 ubiquitin recognition factor in ER associated degradation 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:29,739,062...29,763,315
Ensembl chr26:29,739,153...29,763,313 		JBrowse link
negative regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTNL2 butyrophilin like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16751379) Ensembl
MGI		 PMID:16751379 GO_REF:0000107 NCBI chr12:2,085,589...2,106,787
Ensembl chr12:2,086,324...2,107,124 		JBrowse link
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase involved_in ISO (PMID:38225265) UniProt PMID:38225265 NCBI chr28:13,988,408...14,173,223
Ensembl chr28:13,988,432...14,169,581 		JBrowse link
G CBLB Cbl proto-oncogene B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14738763) Ensembl
MGI		 PMID:14738763 GO_REF:0000107 NCBI chr33:11,255,453...11,665,755
Ensembl chr33:11,199,863...11,530,810 		JBrowse link
G CD160 CD160 molecule involved_in ISO (PMID:18193050) UniProt PMID:18193050 NCBI chr17:58,548,137...58,564,077
Ensembl chr17:58,555,851...58,563,341 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (PMID:18424730) UniProt PMID:18424730 NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830 		JBrowse link
G DGKZ diacylglycerol kinase zeta involved_in ISO (MGI:2672999|PMID:12883552) UniProt PMID:12883552 MGI:2672999 NCBI chr18:43,088,169...43,103,820
Ensembl chr18:43,088,525...43,129,294 		JBrowse link
G DUSP22 dual specificity phosphatase 22 acts_upstream_of_or_within
involved_in		 ISO (PMID:24714587)
(PMID:38225265)		 MGI
UniProt		 PMID:24714587 PMID:38225265 NCBI chr35:678,320...733,225
Ensembl chr35:678,155...732,397 		JBrowse link
G DUSP3 dual specificity phosphatase 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:19,518,302...19,531,000
Ensembl chr 9:19,518,746...19,527,624 		JBrowse link
G ELF1 E74 like ETS transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14738763) Ensembl
MGI		 PMID:14738763 GO_REF:0000107 NCBI chr22:9,565,912...9,671,017
Ensembl chr22:9,592,978...9,670,271 		JBrowse link
G EZR ezrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:48,160,206...48,210,036
Ensembl chr 1:48,160,206...48,210,036 		JBrowse link
G GBP1 guanylate binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:59,378,069...59,393,388
Ensembl chr 6:59,273,592...59,393,229 		JBrowse link
G GBP5 guanylate binding protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:59,273,699...59,292,563
Ensembl chr 6:59,273,592...59,393,229 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870) ARUK-UCL PMID:18619870 MGI:3803048 NCBI chr 2:70,188,382...70,215,361
Ensembl chr 2:70,152,739...70,333,073 		JBrowse link
G LGALS3 galectin 3 involved_in ISO (MGI:4355752|PMID:19706535) BHF-UCL PMID:19706535 MGI:4355752 NCBI chr 8:30,977,438...30,994,711
Ensembl chr 8:30,983,633...30,994,705 		JBrowse link
G LOC100855640 butyrophilin subfamily 2 member A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23589618) Ensembl
MGI		 PMID:23589618 GO_REF:0000107 NCBI chr35:24,251,221...24,265,040
Ensembl chr35:24,251,799...24,262,496 		JBrowse link
G LOC484306 leukocyte immunoglobulin-like receptor subfamily B member 3 involved_in ISO (PMID:22387553)
(PMID:16493035)		 BHF-UCL
ARUK-UCL		 PMID:16493035 PMID:22387553 NCBI chr 1:102,779,562...102,786,924 JBrowse link
G PAWR pro-apoptotic WT1 regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12970181) Ensembl
MGI		 PMID:12970181 GO_REF:0000107 NCBI chr15:22,114,014...22,159,287 JBrowse link
G PHPT1 phosphohistidine phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,736,310...48,737,771
Ensembl chr 9:48,736,333...48,737,725 		JBrowse link
G PRNP prion protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:16,845,224...16,862,319
Ensembl chr24:16,846,207...16,859,815 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:18056643) UniProt PMID:18056643 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9064344) Ensembl
MGI		 PMID:9064344 GO_REF:0000107 NCBI chr27:38,084,976...38,101,552
Ensembl chr27:38,084,980...38,101,937 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:41,586,262...41,635,386
Ensembl chr18:41,586,112...41,635,308 		JBrowse link
G PVRIG PVR related immunoglobulin domain containing involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 6:9,314,959...9,324,544
Ensembl chr 6:9,318,163...9,319,499 		JBrowse link
G SH2D1A SH2 domain containing 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:95,739,568...95,762,117
Ensembl chr  X:95,739,669...95,760,698 		JBrowse link
G SLA2 Src like adaptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:25,396,187...25,426,789
Ensembl chr24:25,396,900...25,422,467 		JBrowse link
G THY1 Thy-1 cell surface antigen involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:14,503,902...14,509,113
Ensembl chr 5:14,503,902...14,509,113 		JBrowse link
G UBASH3A ubiquitin associated and SH3 domain containing A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14738763) Ensembl
MGI
TreeGrafter		 PMID:14738763 GO_REF:0000107 GO_REF:0000118 NCBI chr31:36,735,790...36,778,405
Ensembl chr31:36,735,835...36,778,405 		JBrowse link
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in ISO (MGI:5490396|PMID:23609450) UniProt PMID:23609450 MGI:5490396 NCBI chr22:30,545,991...30,557,199
Ensembl chr22:30,547,271...30,555,510 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:35,579,531...35,676,552
Ensembl chr16:35,579,585...35,674,063 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15220916) Ensembl
MGI		 PMID:15220916 GO_REF:0000107 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISO (PMID:22198949) ARUK-UCL PMID:22198949 NCBI chr 3:73,504,357...73,523,964
Ensembl chr 3:73,520,706...73,523,099 		JBrowse link
negative regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180 		JBrowse link
G RNF170 ring finger protein 170 involved_in ISO (PMID:31076723) UniProt PMID:31076723 NCBI chr16:22,901,224...22,929,990
Ensembl chr16:22,900,313...22,927,125 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:30,247,432...30,262,992
Ensembl chr 1:30,251,059...30,261,001 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:75,767,345...75,812,278
Ensembl chr 1:75,767,188...75,838,051 		JBrowse link
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in ISO (MGI:5490396|PMID:23609450) UniProt PMID:23609450 MGI:5490396 NCBI chr22:30,545,991...30,557,199
Ensembl chr22:30,547,271...30,555,510 		JBrowse link
G BPIFB1 BPI fold containing family B member 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr24:22,510,890...22,531,338
Ensembl chr24:22,511,060...22,531,292 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:60,725,887...60,918,242
Ensembl chr 9:60,726,809...60,918,139 		JBrowse link
G LOC484309 leukocyte immunoglobulin-like receptor subfamily A member 6 involved_in ISO (PMID:22479404) UniProt PMID:22479404 NCBI chr 1:102,995,743...103,014,085 JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:35,579,531...35,676,552
Ensembl chr16:35,579,585...35,674,063 		JBrowse link
G MIR140 microRNA mir-140 involved_in ISO (PMID:30233718)
(PMID:30321456)		 ARUK-UCL PMID:30233718 PMID:30321456 NCBI chr 5:79,814,256...79,814,316
Ensembl chr 5:79,814,246...79,814,326 		JBrowse link
G MIR200B microRNA mir-200b involved_in ISO (PMID:22522429) ARUK-UCL PMID:22522429 NCBI chr 5:56,368,400...56,368,479
Ensembl chr 5:56,368,400...56,368,479 		JBrowse link
G MIR200C microRNA mir-200c involved_in ISO (PMID:22522429) ARUK-UCL PMID:22522429 NCBI chr27:38,082,097...38,082,159
Ensembl chr27:38,082,091...38,082,169 		JBrowse link
G MIR20A microRNA mir-20a involved_in ISO (PMID:29653364) ARUK-UCL PMID:29653364 NCBI chr22:42,478,462...42,478,520
Ensembl chr22:42,478,462...42,478,520 		JBrowse link
G MIR708 microRNA mir-708 involved_in ISO (PMID:31599428) ARUK-UCL PMID:31599428 NCBI chr21:19,542,577...19,542,645
Ensembl chr21:19,542,577...19,542,645 		JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:22,461,556...22,469,243
Ensembl chr 9:22,461,705...22,469,053 		JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:2,333,939...2,359,531
Ensembl chr38:2,335,535...2,359,469 		JBrowse link
G SQSTM1 sequestosome 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:1,859,776...1,869,289
Ensembl chr11:1,859,465...1,870,755 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:40,845,532...40,939,172
Ensembl chr14:40,845,564...40,944,438 		JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 involved_in ISO (PMID:19412184) UniProt PMID:19412184 NCBI chr11:5,312,383...5,313,099
Ensembl chr11:5,312,383...5,313,099 		JBrowse link
G TRIM32 tripartite motif containing 32 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:70,453,130...70,465,030
Ensembl chr11:70,462,007...70,463,974 		JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:30,247,432...30,262,992
Ensembl chr 1:30,251,059...30,261,001 		JBrowse link
negative regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRAMD4 GRAM domain containing 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:19,608,037...19,643,294
Ensembl chr10:19,605,955...19,661,694 		JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in ISO (PMID:14716310) UniProt PMID:14716310 NCBI chr15:2,815,428...2,886,474
Ensembl chr15:2,859,979...2,894,425 		JBrowse link
G PTPRS protein tyrosine phosphatase receptor type S involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:54,575,853...54,672,141
Ensembl chr20:54,575,895...54,672,068 		JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:2,333,939...2,359,531
Ensembl chr38:2,335,535...2,359,469 		JBrowse link
negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB2 arrestin beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:31,831,208...31,838,875
Ensembl chr 5:31,829,864...31,839,454 		JBrowse link
G CACTIN cactin, spliceosome C complex subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,803,494...55,817,467
Ensembl chr20:55,803,530...55,816,549 		JBrowse link
G GPR108 G protein-coupled receptor 108 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:53,554,574...53,560,845
Ensembl chr20:53,554,445...53,565,239 		JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,273,169...32,275,915
Ensembl chr 5:32,273,173...32,275,580 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:8,683,541...8,730,757
Ensembl chr10:8,684,242...8,729,268 		JBrowse link
G IRF4 interferon regulatory factor 4 acts_upstream_of_or_within ISO (PMID:16236719) MGI PMID:16236719 NCBI chr35:760,367...782,314
Ensembl chr35:767,011...781,339 		JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:47,952,019...47,995,530
Ensembl chr21:47,952,890...47,996,288 		JBrowse link
G LRRC14 leucine rich repeat containing 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:37,937,437...37,941,202
Ensembl chr13:37,937,111...37,941,703 		JBrowse link
G MIR140 microRNA mir-140 ISO RGD PMID:31376096 RGD:329337378 NCBI chr 5:79,814,256...79,814,316
Ensembl chr 5:79,814,246...79,814,326 		JBrowse link
G MIR17 microRNA mir-17 involved_in ISO (PMID:26041742) ARUK-UCL PMID:26041742 NCBI chr22:42,478,013...42,478,071
Ensembl chr22:42,478,000...42,478,083 		JBrowse link
G MIR19A microRNA mir-19a involved_in ISO (PMID:26041742) ARUK-UCL PMID:26041742 NCBI chr22:42,478,298...42,478,355
Ensembl chr22:42,478,285...42,478,366 		JBrowse link
G NFKBIL1 NFKB inhibitor like 1 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:1,048,393...1,057,458
Ensembl chr12:1,049,109...1,057,237 		JBrowse link
G NLRP6 NLR family pyrin domain containing 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22763455) Ensembl
MGI		 PMID:22763455 GO_REF:0000107 NCBI chr18:25,433,481...25,440,703
Ensembl chr18:25,433,698...25,440,740 		JBrowse link
G OTUD4 OTU deubiquitinase 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:43,816,656...43,861,813
Ensembl chr15:43,818,196...43,861,784 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,426,464...38,506,520
Ensembl chr 6:38,431,600...38,499,295 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (MGI:5487531|PMID:20728433) UniProt PMID:20728433 MGI:5487531 NCBI chr28:9,977,463...10,095,363
Ensembl chr28:9,978,900...10,095,284 		JBrowse link
G RNF115 ring finger protein 115 involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chr17:58,566,761...58,634,967
Ensembl chr17:58,571,694...58,660,663 		JBrowse link
G SMPDL3B sphingomyelin phosphodiesterase acid like 3B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:72,427,085...72,450,547
Ensembl chr 2:72,418,872...72,450,737 		JBrowse link
G TRIM22 tripartite motif containing 22 involved_in ISO (MGI:3778152|PMID:18345001) UniProt PMID:18345001 MGI:3778152 NCBI chr21:28,677,196...28,696,413
Ensembl chr21:28,682,973...28,695,185 		JBrowse link
G TYRO3 TYRO3 protein tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:8,571,230...8,602,655
Ensembl chr30:8,571,475...8,598,721 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chr 9:45,506,830...45,562,081
Ensembl chr 9:45,507,282...45,562,086 		JBrowse link
NLRP1 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLRP1 NLR family pyrin domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:31,264,554...31,299,538
Ensembl chr 5:31,266,621...31,299,304 		JBrowse link
NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAT1 alpha tubulin acetyltransferase 1 acts_upstream_of ISO (PMID:23502856) MGI PMID:23502856 NCBI chr12:441,847...456,349
Ensembl chr12:441,895...456,152 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28928055) Ensembl
MGI		 PMID:28928055 GO_REF:0000107 NCBI chr27:25,368,565...25,375,754
Ensembl chr27:25,368,810...25,375,009 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in
acts_upstream_of_or_within		 ISO (PMID:17483456), (PMID:23582325), (PMID:25686105), (PMID:27043286), (PMID:27432880), (PMID:28465465), (PMID:28656979), (PMID:28943315), (PMID:30487600), (PMID:31189953), (PMID:33231615), (PMID:34554188), (PMID:34615873), (PMID:35114687), (PMID:35254907), (PMID:35559676), (PMID:36442502)
(PMID:22753929)
(MGI:5492224|PMID:23582325), (MGI:5792478|PMID:27043286), (MGI:5913002|PMID:28716882), (MGI:5921465|PMID:28656979), (MGI:6106673|PMID:28943315), (MGI:6260219|PMID:30487600), (MGI:6787653|PMID:34615873), (MGI:6844859|PMID:34861190), (MGI:6859739|PMID:28465465), (PMID:26173909)		 UniProt
MGI		 PMID:17483456 PMID:22753929 PMID:23582325 PMID:25686105 PMID:26173909 More... MGI:5492224 MGI:5792478 MGI:5913002 MGI:5921465 MGI:6106673 MGI:6260219 MGI:6787653 MGI:6844859 MGI:6859739 NCBI chr 8:251,776...313,290
Ensembl chr 8:253,407...313,059 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:17,049,352...17,051,348
Ensembl chr 6:17,049,705...17,051,240 		JBrowse link
G SIRT2 sirtuin 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23502856) Ensembl
MGI		 PMID:23502856 GO_REF:0000107 NCBI chr 1:114,224,922...114,235,041
Ensembl chr 1:114,224,900...114,234,583 		JBrowse link
NLRP6 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLRP6 NLR family pyrin domain containing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:25,433,481...25,440,703
Ensembl chr18:25,433,698...25,440,740 		JBrowse link
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF34 ring finger protein 34 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:7,746,460...7,767,967
Ensembl chr26:7,744,924...7,767,892 		JBrowse link
nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFKBIA NFKB inhibitor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 8:14,100,203...14,103,453
Ensembl chr 8:14,100,671...14,103,433 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:43,162,671...43,226,948
Ensembl chr14:43,163,571...43,227,103 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894098) Ensembl
MGI		 PMID:11894098 GO_REF:0000107 NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:95,300,234...95,356,103
Ensembl chr  X:95,331,827...95,351,582 		JBrowse link
nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INAVA innate immunity activator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:2,264,120...2,284,196 JBrowse link
G LACC1 laccase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:6,824,942...7,002,888 JBrowse link
G LOC481473 immunity-related GTPase family M protein involved_in ISO (PMID:25891078) UniProt PMID:25891078 NCBI chr11:793,416...795,373
Ensembl chr11:793,424...794,617 		JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 8:14,100,203...14,103,453
Ensembl chr 8:14,100,671...14,103,433 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12527755)
(PMID:23892723)		 MGI
Ensembl		 PMID:12527755 PMID:23892723 GO_REF:0000107 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232 		JBrowse link
G OTULIN OTU deubiquitinase with linear linkage specificity involved_in ISO (PMID:23806334) UniProt PMID:23806334 NCBI chr34:119,307...159,419
Ensembl chr34:122,274...159,394 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12527755) MGI
Ensembl		 PMID:12527755 GO_REF:0000107 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894098) Ensembl
MGI		 PMID:11894098 GO_REF:0000107 NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:95,300,234...95,356,103
Ensembl chr  X:95,331,827...95,351,582 		JBrowse link
pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CGAS cyclic GMP-AMP synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:35,511,920...35,528,759
Ensembl chr12:35,512,860...35,528,596 		JBrowse link
G INAVA innate immunity activator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:2,264,120...2,284,196 JBrowse link
G LACC1 laccase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:6,824,942...7,002,888 JBrowse link
G LOC611538 C-type lectin domain family 4 member E involved_in ISO (PMID:24101491) UniProt PMID:24101491 NCBI chr27:37,561,445...37,568,652
Ensembl chr27:37,563,038...37,568,463 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:43,162,671...43,226,948
Ensembl chr14:43,163,571...43,227,103 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232 		JBrowse link
G RNF144A ring finger protein 144A involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:4,522,095...4,637,741
Ensembl chr17:4,519,904...4,662,833 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:34,783,947...34,792,204
Ensembl chr 2:34,784,232...34,789,072 		JBrowse link
positive regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GBP5 guanylate binding protein 5 involved_in ISO (MGI:5774627|PMID:25774716), (MGI:5774628|PMID:25774715) UniProt PMID:25774715 PMID:25774716 MGI:5774627 MGI:5774628 NCBI chr 6:59,273,699...59,292,563
Ensembl chr 6:59,273,592...59,393,229 		JBrowse link
positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPRC protein tyrosine phosphatase receptor type C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124 		JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule involved_in ISO (MGI:5476553|PMID:23499492)
(PMID:20237408)		 UniProt PMID:20237408 PMID:23499492 MGI:5476553 NCBI chr18:46,466,484...46,474,236
Ensembl chr18:46,466,499...46,473,868 		JBrowse link
G CMTM3 CKLF like MARVEL transmembrane domain containing 3 acts_upstream_of_or_within ISO (PMID:15196959) MGI PMID:15196959 NCBI chr 5:82,660,995...82,667,360
Ensembl chr 5:82,661,256...82,667,372 		JBrowse link
G FOXP1 forkhead box P1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:20,438,631...21,020,516
Ensembl chr20:20,788,433...21,016,397 		JBrowse link
G MIR18A microRNA mir-18a involved_in ISO (PMID:24169826) ARUK-UCL PMID:24169826 NCBI chr22:42,478,138...42,478,229
Ensembl chr22:42,478,138...42,478,229 		JBrowse link
G MIR19A microRNA mir-19a involved_in ISO (PMID:24169826), (PMID:26017478) ARUK-UCL PMID:24169826 PMID:26017478 NCBI chr22:42,478,298...42,478,355
Ensembl chr22:42,478,285...42,478,366 		JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr10:23,008,084...23,047,227
Ensembl chr10:23,008,393...23,045,565 		JBrowse link
G PRKCB protein kinase C beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:21,742,970...22,064,360
Ensembl chr 6:21,742,973...22,065,185 		JBrowse link
G PRKCH protein kinase C eta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:36,185,430...36,452,893
Ensembl chr 8:36,219,212...36,451,777 		JBrowse link
G SLC39A10 solute carrier family 39 member 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25074919) Ensembl
MGI		 PMID:25074919 GO_REF:0000107 NCBI chr37:5,482,200...5,521,104
Ensembl chr37:5,482,177...5,521,110 		JBrowse link
G STAP1 signal transducing adaptor family member 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr13:58,091,457...58,148,902
Ensembl chr13:58,091,477...58,133,711 		JBrowse link
positive regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:37832545) UniProt PMID:37832545 NCBI chr12:49,669,849...49,740,039
Ensembl chr12:49,672,389...49,739,850 		JBrowse link
G SLC19A1 solute carrier family 19 member 1 involved_in ISO (PMID:36745868) UniProt PMID:36745868 NCBI chr31:38,958,332...38,971,091
Ensembl chr31:38,967,013...38,971,094 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:25,623,381...25,657,630
Ensembl chr10:25,623,940...25,657,543 		JBrowse link
G ZDHHC9 zinc finger DHHC-type palmitoyltransferase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:101,011,072...101,096,394
Ensembl chr  X:100,996,607...101,043,228 		JBrowse link
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD226 CD226 molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:8,348,628...8,437,520
Ensembl chr 1:8,351,207...8,435,145 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:16177098 RGD:1578516 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:41,586,262...41,635,386
Ensembl chr18:41,586,112...41,635,308 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO RGD PMID:18832707 RGD:9835043 NCBI chr17:63,725,812...63,795,359
Ensembl chr17:63,726,248...63,746,881 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO RGD PMID:18832707 RGD:9835043 NCBI chr 9:52,429,204...52,566,775
Ensembl chr 9:52,450,597...52,563,778 		JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:33,192,261...33,243,034
Ensembl chr10:33,191,602...33,242,669 		JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR4A3 nuclear receptor subfamily 4 group A member 3 involved_in ISO (MGI:5586645|PMID:24586680) UniProt PMID:24586680 MGI:5586645 NCBI chr11:56,806,506...56,846,997
Ensembl chr11:56,812,804...56,847,689 		JBrowse link
positive regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD17 ankyrin repeat domain 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:61,892,872...62,046,625
Ensembl chr13:61,893,951...62,012,404 		JBrowse link
G DDX60 DExD/H-box helicase 60 involved_in ISO (PMID:21791617) UniProt PMID:21791617 NCBI chr15:63,649,441...63,741,357
Ensembl chr15:63,649,875...63,734,920 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,787,470...20,795,593
Ensembl chr 9:20,787,541...20,795,361 		JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAT1 alpha tubulin acetyltransferase 1 acts_upstream_of_or_within ISO (PMID:23502856) MGI PMID:23502856 NCBI chr12:441,847...456,349
Ensembl chr12:441,895...456,152 		JBrowse link
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISO (PMID:28943315)
(MGI:7387171|PMID:23246432)		 UniProt PMID:23246432 PMID:28943315 MGI:7387171 NCBI chr  X:123,081,262...123,143,509
Ensembl chr  X:123,081,050...123,140,133 		JBrowse link
G BTK Bruton tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:75,270,952...75,302,663
Ensembl chr  X:75,270,979...75,302,562 		JBrowse link
G CASP4 caspase 4, apoptosis-related cysteine peptidase involved_in ISO (MGI:5780643|PMID:26173909) UniProt PMID:26173909 MGI:5780643 NCBI chr 5:27,133,778...27,147,954
Ensembl chr 5:27,132,565...27,149,736 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:20,299,808...20,375,856
Ensembl chr18:20,339,050...20,372,639 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in ISO (MGI:6368386|PMID:31511697) UniProt PMID:31511697 MGI:6368386 NCBI chr  X:35,759,367...35,789,759
Ensembl chr  X:35,759,416...35,789,774 		JBrowse link
G DHX33 DEAH-box helicase 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:31,337,447...31,351,447
Ensembl chr 5:31,338,620...31,346,422 		JBrowse link
G GBP5 guanylate binding protein 5 involved_in ISO (PMID:22461501) UniProt PMID:22461501 NCBI chr 6:59,273,699...59,292,563
Ensembl chr 6:59,273,592...59,393,229 		JBrowse link
G LOC102154691 short transmembrane mitochondrial protein 1 involved_in ISO (MGI:6384515|PMID:31836654) UniProt PMID:31836654 MGI:6384515 NCBI chr10:5,562,521...5,563,107
Ensembl chr16:12,586,975...12,602,256 		JBrowse link
G LOC119881800 serine/threonine-protein phosphatase 2A catalytic subunit involved_in IEA Ensembl GO_REF:0000107
G MAPK8 mitogen-activated protein kinase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:323,361...410,367
Ensembl chr28:368,513...406,401 		JBrowse link
G MARK4 microtubule affinity regulating kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:110,222,760...110,248,745
Ensembl chr 1:110,222,754...110,247,411 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:17,510,209...17,529,286
Ensembl chr24:17,512,761...17,523,807 		JBrowse link
G MIR21 microRNA mir-21 ISO RGD PMID:29084974 RGD:41404715 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534 		JBrowse link
G NEK7 NIMA related kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:4,557,754...4,755,912
Ensembl chr 7:4,555,231...4,704,955 		JBrowse link
G PLCG2 phospholipase C gamma 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:32514138) ARUK-UCL
Ensembl		 PMID:32514138 GO_REF:0000107 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:22,388,327...22,410,052
Ensembl chr11:22,385,257...22,410,052 		JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:33,532,703...33,567,011
Ensembl chr16:33,532,958...33,566,640 		JBrowse link
G PRKD1 protein kinase D1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:9,004,641...9,327,054
Ensembl chr 8:9,005,115...9,328,358 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858 		JBrowse link
G TLR4 toll like receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISO (MGI:5546292|PMID:23812099) UniProt PMID:23812099 MGI:5546292 NCBI chr 3:73,504,357...73,523,964
Ensembl chr 3:73,520,706...73,523,099 		JBrowse link
G USP50 ubiquitin specific peptidase 50 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:28094437) MGI
Ensembl		 PMID:28094437 GO_REF:0000107 NCBI chr30:16,409,293...16,453,788
Ensembl chr30:16,409,294...16,453,728 		JBrowse link
G ZDHHC5 zinc finger DHHC-type palmitoyltransferase 5 involved_in ISO (PMID:38092000) UniProt PMID:38092000 NCBI chr18:38,497,649...38,522,728
Ensembl chr18:38,497,657...38,517,964 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:2,803,798...2,832,057
Ensembl chr26:2,802,724...2,831,530 		JBrowse link
G SLC46A2 solute carrier family 46 member 2 involved_in ISO (PMID:28539433) FlyBase PMID:28539433 NCBI chr11:67,297,596...67,305,893
Ensembl chr11:67,297,597...67,305,893 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSP70 heat shock protein 70 involved_in ISO (PMID:24790089) UniProt PMID:24790089 NCBI chr12:1,285,282...1,287,670 JBrowse link
G NAGK N-acetylglucosamine kinase involved_in ISO (PMID:36002575)
(MGI:7484284|PMID:36002575)		 UniProt PMID:36002575 MGI:7484284 NCBI chr17:51,367,477...51,376,461 JBrowse link
G PELI3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chr18:50,870,483...50,881,089
Ensembl chr18:50,872,426...50,879,826 		JBrowse link
G SLC15A3 solute carrier family 15 member 3 involved_in ISO (MGI:5571205|PMID:24695226) UniProt PMID:24695226 MGI:5571205 NCBI chr18:55,354,987...55,363,672 JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:2,803,798...2,832,057
Ensembl chr26:2,802,724...2,831,530 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
positive regulation of pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZDHHC5 zinc finger DHHC-type palmitoyltransferase 5 involved_in ISO (MGI:6414746|PMID:31649195)
(PMID:31649195)		 UniProt PMID:31649195 MGI:6414746 NCBI chr18:38,497,649...38,522,728
Ensembl chr18:38,497,657...38,517,964 		JBrowse link
positive regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD17 ankyrin repeat domain 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:61,892,872...62,046,625
Ensembl chr13:61,893,951...62,012,404 		JBrowse link
G DDX60 DExD/H-box helicase 60 involved_in ISO (PMID:21791617) UniProt PMID:21791617 NCBI chr15:63,649,441...63,741,357
Ensembl chr15:63,649,875...63,734,920 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,787,470...20,795,593
Ensembl chr 9:20,787,541...20,795,361 		JBrowse link
G OASL 2'-5'-oligoadenylate synthetase like involved_in ISO (PMID:25925578) ARUK-UCL PMID:25925578 NCBI chr26:16,837,376...16,850,388
Ensembl chr26:16,837,376...16,850,388 		JBrowse link
G PUM1 pumilio RNA binding family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:69,907,655...70,044,055
Ensembl chr 2:69,907,735...70,042,680 		JBrowse link
G PUM2 pumilio RNA binding family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,258,264...15,354,001
Ensembl chr17:15,261,389...15,354,586 		JBrowse link
G USP15 ubiquitin specific peptidase 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:5,510,759...5,634,954
Ensembl chr10:5,510,022...5,634,202 		JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 involved_in ISO (PMID:21102435) UniProt PMID:21102435 NCBI chr16:9,598,339...9,660,540
Ensembl chr16:9,598,405...9,664,569 		JBrowse link
G ZCCHC3 zinc finger CCHC-type containing 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr24:20,537,849...20,540,098 JBrowse link
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11435465) Ensembl
MGI		 PMID:11435465 GO_REF:0000107 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160 		JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:62,712,937...62,723,852
Ensembl chr 6:62,712,971...62,722,368 		JBrowse link
G CARD11 caspase recruitment domain family member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:14,273,115...14,331,029
Ensembl chr 6:14,210,114...14,332,094 		JBrowse link
G CCR7 C-C motif chemokine receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:22,077,976...22,092,818
Ensembl chr 9:22,068,775...22,090,656 		JBrowse link
G CD226 CD226 molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:8,348,628...8,437,520
Ensembl chr 1:8,351,207...8,435,145 		JBrowse link
G CD81 CD81 molecule involved_in ISO (PMID:23858057) UniProt PMID:23858057 NCBI chr18:46,466,484...46,474,236
Ensembl chr18:46,466,499...46,473,868 		JBrowse link
G CYLD CYLD lysine 63 deubiquitinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16501569) Ensembl
MGI		 PMID:16501569 GO_REF:0000107 NCBI chr 2:64,561,684...64,628,829
Ensembl chr 2:64,562,503...64,628,175 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:122,232,052...122,253,499
Ensembl chr  X:122,235,878...122,250,562 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:111,391,464...111,407,612
Ensembl chr 1:111,391,159...111,407,701 		JBrowse link
G LIPA lipase A, lysosomal acid type acts_upstream_of_or_within ISO (PMID:19179613) MGI PMID:19179613 NCBI chr26:38,892,771...38,918,441
Ensembl chr26:38,893,337...38,918,436 		JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:110,543,140...110,569,168
Ensembl chr 1:110,543,247...110,569,143 		JBrowse link
G PRKD2 protein kinase D2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:109,206,400...109,241,529
Ensembl chr 1:109,207,067...109,330,007 		JBrowse link
G PVR PVR cell adhesion molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:110,692,906...110,713,209
Ensembl chr 1:110,697,911...110,754,296 		JBrowse link
G RAB29 RAB29, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:2,196,618...2,204,150
Ensembl chr38:2,198,040...2,203,896 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875 		JBrowse link
G RPS3 ribosomal protein S3 involved_in ISO (PMID:18045535) CAFA PMID:18045535 NCBI chr21:23,180,515...23,187,034
Ensembl chr21:23,180,515...23,187,034 		JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr27:424,836...460,114
Ensembl chr27:424,715...460,097 		JBrowse link
G TRAT1 T cell receptor associated transmembrane adaptor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11390434) MGI
TreeGrafter
Ensembl		 PMID:11390434 GO_REF:0000107 GO_REF:0000118 NCBI chr33:14,033,597...14,068,309
Ensembl chr33:14,033,657...14,067,974 		JBrowse link
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 involved_in ISO (PMID:38225265) UniProt PMID:38225265 NCBI chr12:11,167,286...11,296,817
Ensembl chr12:11,167,346...11,294,911 		JBrowse link
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYBA cytochrome b-245 alpha chain involved_in ISO (PMID:22423966) UniProt PMID:22423966 NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (MGI:5788395|PMID:16267105) UniProt PMID:16267105 MGI:5788395 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:35,579,531...35,676,552
Ensembl chr16:35,579,585...35,674,063 		JBrowse link
G PJA2 praja ring finger ubiquitin ligase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:2,689,238...2,797,142
Ensembl chr 3:2,751,201...2,794,381 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:8,222,217...8,237,595
Ensembl chr 5:8,221,794...8,226,074 		JBrowse link
G TLR1 toll like receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:73,504,359...73,544,822
Ensembl chr 3:73,539,715...73,544,624 		JBrowse link
positive regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180 		JBrowse link
G FLOT1 flotillin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:517,941...528,677
Ensembl chr12:516,032...528,637 		JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19734906) Ensembl
MGI		 PMID:19734906 GO_REF:0000107 NCBI chr10:63,727,905...63,863,599
Ensembl chr10:63,729,604...63,743,303 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in ISO (MGI:4943396|PMID:17322885) BHF-UCL PMID:17322885 MGI:4943396 NCBI chr 5:8,222,217...8,237,595
Ensembl chr 5:8,221,794...8,226,074 		JBrowse link
G TRIM3 tripartite motif containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:29,766,086...29,782,573
Ensembl chr21:29,766,094...29,782,538 		JBrowse link
G WDFY1 WD repeat and FYVE domain containing 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr37:29,544,956...29,658,544
Ensembl chr37:29,444,082...29,677,312 		JBrowse link
positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:35,790,505...35,792,967 JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (MGI:5788395|PMID:16267105) UniProt PMID:16267105 MGI:5788395 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165 		JBrowse link
G IFI35 interferon induced protein 35 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,050,438...20,061,346
Ensembl chr 9:20,050,438...20,061,319 		JBrowse link
G LBP lipopolysaccharide binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:26,810,369...26,833,515
Ensembl chr24:26,809,843...26,833,434 		JBrowse link
G LTF lactotransferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:42,231,994...42,263,202
Ensembl chr20:42,231,994...42,263,202 		JBrowse link
G NINJ1 ninjurin 1 involved_in ISO (MGI:6694429|PMID:25860173) UniProt PMID:25860173 MGI:6694429 NCBI chr 1:98,566,520...98,576,668
Ensembl chr 1:98,567,680...98,576,657 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,333,173...42,346,152
Ensembl chr18:42,333,202...42,341,236 		JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19734906) Ensembl
MGI		 PMID:19734906 GO_REF:0000107 NCBI chr10:63,727,905...63,863,599
Ensembl chr10:63,729,604...63,743,303 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858 		JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 involved_in ISO (PMID:22685567)
(PMID:19412184)		 UniProt PMID:19412184 PMID:22685567 NCBI chr11:5,312,383...5,313,099
Ensembl chr11:5,312,383...5,313,099 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:8,222,217...8,237,595
Ensembl chr 5:8,221,794...8,226,074 		JBrowse link
G WDFY1 WD repeat and FYVE domain containing 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr37:29,544,956...29,658,544
Ensembl chr37:29,444,082...29,677,312 		JBrowse link
G ZNRF1 zinc and ring finger 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:75,594,465...75,698,164
Ensembl chr 5:75,595,200...75,698,170 		JBrowse link
positive regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX3X DEAD-box helicase 3 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:35,759,367...35,789,759
Ensembl chr  X:35,759,416...35,789,774 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858 		JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:4,488,202...4,508,705
Ensembl chr17:4,487,957...4,507,181 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:2,803,798...2,832,057
Ensembl chr26:2,802,724...2,831,530 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:32433612) UniProt PMID:32433612 NCBI chr  X:25,664,361...25,679,044 JBrowse link
positive regulation of toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX3X DEAD-box helicase 3 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:35,759,367...35,789,759
Ensembl chr  X:35,759,416...35,789,774 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:2,803,798...2,832,057
Ensembl chr26:2,802,724...2,831,530 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:32433612) UniProt PMID:32433612 NCBI chr  X:25,664,361...25,679,044 JBrowse link
positive regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858 		JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:4,488,202...4,508,705
Ensembl chr17:4,487,957...4,507,181 		JBrowse link
G RTN4 reticulon 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:55,884,452...55,954,476
Ensembl chr10:55,885,125...55,936,574 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:2,803,798...2,832,057
Ensembl chr26:2,802,724...2,831,530 		JBrowse link
G TLR9 toll like receptor 9 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114 		JBrowse link
G ZDHHC3 zinc finger DHHC-type palmitoyltransferase 3 involved_in ISO (PMID:38169466) UniProt PMID:38169466 NCBI chr20:43,379,669...43,433,101
Ensembl chr20:43,379,722...43,431,414 		JBrowse link
positive regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GDI1 GDP dissociation inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:122,141,633...122,146,724
Ensembl chr  X:122,141,566...122,146,824 		JBrowse link
G LRCH4 leucine rich repeats and calponin homology domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:9,088,815...9,113,629
Ensembl chr 6:9,020,415...9,113,368 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (MGI:5487531|PMID:20728433) UniProt PMID:20728433 MGI:5487531 NCBI chr28:9,977,463...10,095,363
Ensembl chr28:9,978,900...10,095,284 		JBrowse link
regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD19 CD19 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,419,092...18,425,524
Ensembl chr 6:18,418,241...18,425,400 		JBrowse link
G FCMR Fc mu receptor involved_in ISO (MGI:5888941|PMID:28135254) UniProt PMID:28135254 MGI:5888941 NCBI chr 7:6,046,270...6,064,063
Ensembl chr 7:6,048,814...6,064,013 		JBrowse link
G GCSAM germinal center associated signaling and motility involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr33:16,742,708...16,754,445
Ensembl chr33:16,744,212...16,754,026 		JBrowse link
G GCSAML germinal center associated signaling and motility like involved_in IEA InterPro GO_REF:0000002 NCBI chr 8:514,775...549,584
Ensembl chr 8:514,659...549,427 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507 		JBrowse link
regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR708 microRNA mir-708 involved_in ISO (PMID:31599428) ARUK-UCL PMID:31599428 NCBI chr21:19,542,577...19,542,645
Ensembl chr21:19,542,577...19,542,645 		JBrowse link
regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD47 CD47 molecule involved_in ISO PMID:21401967 ARUK-UCL PMID:21401967 RGD:13792533 NCBI chr33:13,315,984...13,362,971
Ensembl chr33:13,319,266...13,363,580 		JBrowse link
G CSK C-terminal Src kinase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:9325302 GO_REF:0000118 RGD:2303720 NCBI chr30:37,851,269...37,870,382
Ensembl chr30:37,852,046...37,870,378 		JBrowse link
G PLSCR1 phospholipid scramblase 1 involved_in ISO PMID:18579528 UniProt PMID:18579528 RGD:2303650 NCBI chr23:41,639,938...41,668,972
Ensembl chr23:41,599,843...41,669,112 		JBrowse link
G PTEN phosphatase and tensin homolog ISO negative regulation RGD PMID:18056380 RGD:2292524 NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176 		JBrowse link
G RABGEF1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (PMID:17341663)
(PMID:15235600)		 MGI PMID:15235600 PMID:17341663 NCBI chr 6:1,064,694...1,159,906
Ensembl chr 6:1,064,655...1,179,547 		JBrowse link
regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRF1 interferon regulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:20,773,801...20,781,106
Ensembl chr11:20,760,120...20,781,608 		JBrowse link
G IRF7 interferon regulatory factor 7 involved_in ISO (MGI:3575992|PMID:15800576) UniProt PMID:15800576 MGI:3575992
regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRF7 interferon regulatory factor 7 involved_in ISO (MGI:3575992|PMID:15800576) UniProt PMID:15800576 MGI:3575992
regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:29,494,641...29,537,933
Ensembl chr17:29,496,128...29,537,933 		JBrowse link
regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC15A2 solute carrier family 15 member 2 involved_in ISO (MGI:6192142|PMID:29784761) UniProt PMID:29784761 MGI:6192142 NCBI chr33:25,154,415...25,190,715
Ensembl chr33:25,154,448...25,189,929 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:2,803,798...2,832,057
Ensembl chr26:2,802,724...2,831,530 		JBrowse link
regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PELI3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chr18:50,870,483...50,881,089
Ensembl chr18:50,872,426...50,879,826 		JBrowse link
regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOP53 NOP53 ribosome biogenesis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:108,307,039...108,315,732
Ensembl chr 1:108,307,042...108,316,495 		JBrowse link
regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL10 BCL10 immune signaling adaptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14614861) Ensembl
MGI		 PMID:14614861 GO_REF:0000107 NCBI chr 6:62,712,937...62,723,852
Ensembl chr 6:62,712,971...62,722,368 		JBrowse link
G CD300A CD300a molecule involved_in ISO (PMID:22046970) UniProt PMID:22046970 NCBI chr 9:5,952,428...5,976,328 JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:14752163) MGI PMID:14752163 NCBI chr 2:68,940,816...68,964,585
Ensembl chr 2:68,941,249...68,964,567 		JBrowse link
G MALT1 MALT1 paracaspase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14614861) Ensembl
MGI		 PMID:14614861 GO_REF:0000107 NCBI chr 1:17,351,458...17,412,591
Ensembl chr 1:17,354,926...17,403,927 		JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,265,836...25,312,417
Ensembl chr 7:25,233,235...25,305,174 		JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 acts_upstream_of ISO (PMID:28598420) MGI PMID:28598420 NCBI chr27:424,836...460,114
Ensembl chr27:424,715...460,097 		JBrowse link
regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHRS13 dehydrogenase/reductase 13 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chr 9:43,050,929...43,066,886
Ensembl chr 9:43,052,114...43,071,742 		JBrowse link
G HCFC2 host cell factor C2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28970238) Ensembl
MGI		 PMID:28970238 GO_REF:0000107 NCBI chr15:42,560,028...42,596,335
Ensembl chr15:42,560,075...42,597,330 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077 		JBrowse link
regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,123,577...33,166,831
Ensembl chr20:33,130,723...33,166,792 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:33,192,261...33,243,034
Ensembl chr10:33,191,602...33,242,669 		JBrowse link
G FLOT1 flotillin 1 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chr12:517,941...528,677
Ensembl chr12:516,032...528,637 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970 		JBrowse link
regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCRL3 Fc receptor like 3 involved_in ISO (PMID:23857366) UniProt PMID:23857366 NCBI chr 7:40,599,319...40,625,939 JBrowse link
G TLR9 toll like receptor 9 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114 		JBrowse link
regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:20,299,808...20,375,856
Ensembl chr18:20,339,050...20,372,639 		JBrowse link
G ESR1 estrogen receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22659029) Ensembl
MGI		 PMID:22659029 GO_REF:0000107 NCBI chr 1:42,081,952...42,368,544
Ensembl chr 1:42,081,969...42,368,544 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:20547752) UniProt PMID:20547752 NCBI chr 6:56,473,032...56,484,422
Ensembl chr 6:56,256,305...56,484,422 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:35,579,531...35,676,552
Ensembl chr16:35,579,585...35,674,063 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:25,664,361...25,679,044 JBrowse link
RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLPB ClpB family mitochondrial disaggregase involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:25,710,634...25,855,418
Ensembl chr21:25,710,723...25,852,857 		JBrowse link
G LSM14A LSM14A mRNA processing body assembly factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22745163) Ensembl
MGI		 PMID:22745163 GO_REF:0000107 NCBI chr 1:118,061,854...118,117,493
Ensembl chr 1:118,063,512...118,117,478 		JBrowse link
G MAVS mitochondrial antiviral signaling protein acts_upstream_of_or_within ISO (PMID:22745163) MGI PMID:22745163 NCBI chr24:17,510,209...17,529,286
Ensembl chr24:17,512,761...17,523,807 		JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:10,404,548...10,423,039
Ensembl chr26:10,404,414...10,423,039 		JBrowse link
G PHB1 prohibitin 1 involved_in ISO (PMID:31522117) UniProt PMID:31522117 NCBI chr 9:25,525,711...25,536,722
Ensembl chr 9:25,526,649...25,536,722 		JBrowse link
G PHB2 prohibitin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,075,769...38,080,440
Ensembl chr27:38,075,652...38,080,109 		JBrowse link
G RIGI RNA sensor RIG-I involved_in ISO (PMID:28469175)
(PMID:19211564)		 UniProt PMID:19211564 PMID:28469175 NCBI chr11:49,764,252...49,799,626
Ensembl chr11:49,764,267...49,799,527 		JBrowse link
G RNF135 ring finger protein 135 involved_in ISO (PMID:23950712)
(MGI:6152590|PMID:21147464), (MGI:6377978|PMID:28469175)
(PMID:28469175), (PMID:31006531)		 UniProt PMID:21147464 PMID:23950712 PMID:28469175 PMID:31006531 MGI:6152590 MGI:6377978 NCBI chr 9:40,794,772...40,809,022
Ensembl chr 9:40,795,297...40,808,737 		JBrowse link
G TRIM25 tripartite motif containing 25 NOT|involved_in ISO (PMID:31006531) UniProt PMID:31006531 NCBI chr 9:31,703,628...31,725,674
Ensembl chr 9:31,707,034...31,725,762 		JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC7A C-type lectin domain containing 7A involved_in ISO (MGI:3844414|PMID:19136564) ARUK-UCL PMID:19136564 MGI:3844414 NCBI chr27:35,852,685...35,885,673
Ensembl chr27:35,853,099...36,007,157 		JBrowse link
G KLRD1 killer cell lectin like receptor D1 involved_in ISS
IEA
IBA		 UniProt
TreeGrafter
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr27:35,700,879...35,707,270
Ensembl chr27:35,701,185...35,706,720 		JBrowse link
G KLRK1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12645935) Ensembl
MGI		 PMID:12645935 GO_REF:0000107 NCBI chr27:35,634,938...35,658,978
Ensembl chr27:35,639,280...35,658,882 		JBrowse link
G LOC100683252 C-type lectin domain family 9 member A-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr27:35,185,683...35,214,941 JBrowse link
G LOC119866326 NKG2-A/NKG2-B type II integral membrane protein-like involved_in IEA TreeGrafter GO_REF:0000118
G LOC486692 NKG2-A/NKG2-B type II integral membrane protein-like involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chr27:35,534,620...35,584,473 JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583 		JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chr 1:116,757,271...116,760,453
Ensembl chr 1:116,757,289...116,772,325 		JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chr 1:116,757,271...116,760,453
Ensembl chr 1:116,757,289...116,772,325 		JBrowse link
T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18305217) Ensembl
MGI		 PMID:18305217 GO_REF:0000107 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307 		JBrowse link
G ADA adenosine deaminase involved_in
acts_upstream_of		 IEA
ISO		 (PMID:11435465) Ensembl
MGI		 PMID:11435465 GO_REF:0000107 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160 		JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:62,712,937...62,723,852
Ensembl chr 6:62,712,971...62,722,368 		JBrowse link
G BMX BMX non-receptor tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:11,742,805...11,795,437
Ensembl chr  X:11,738,365...11,795,436 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18228248) Ensembl
MGI		 PMID:18228248 GO_REF:0000107 NCBI chr16:8,222,909...8,318,179
Ensembl chr16:8,222,907...8,317,906 		JBrowse link
G BTK Bruton tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:75,270,952...75,302,663
Ensembl chr  X:75,270,979...75,302,562 		JBrowse link
G BTN1A1 butyrophilin subfamily 1 member A1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr35:24,282,445...24,290,261
Ensembl chr35:24,282,590...24,289,167 		JBrowse link
G BTNL2 butyrophilin like 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:2,085,589...2,106,787
Ensembl chr12:2,086,324...2,107,124 		JBrowse link
G BTNL9 butyrophilin like 9 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:234,595...271,623
Ensembl chr11:234,580...270,121 		JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17028169) Ensembl
MGI		 PMID:17028169 GO_REF:0000107 NCBI chr27:5,705,587...5,714,620
Ensembl chr27:5,706,064...5,717,647 		JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15637280), (PMID:17028169) Ensembl
MGI		 PMID:15637280 PMID:17028169 GO_REF:0000107 NCBI chr19:52,987,170...53,116,410
Ensembl chr19:52,993,618...53,116,140
Ensembl chr19:52,993,618...53,116,140 		JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (PMID:23793062) MGI PMID:23793062 NCBI chr 5:81,792,683...81,804,274
Ensembl chr 5:81,792,155...81,804,152 		JBrowse link
G CBLB Cbl proto-oncogene B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12697763) Ensembl
MGI		 PMID:12697763 GO_REF:0000107 NCBI chr33:11,255,453...11,665,755
Ensembl chr33:11,199,863...11,530,810 		JBrowse link
G CD247 CD247 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11435465) TreeGrafter
MGI		 PMID:11435465 GO_REF:0000118 NCBI chr 7:30,961,169...30,972,143 JBrowse link
G CD276 CD276 molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr30:36,975,085...36,990,012
Ensembl chr30:36,975,085...36,988,924 		JBrowse link
G CD28 CD28 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23793062) Ensembl
MGI
TreeGrafter		 PMID:23793062 GO_REF:0000107 GO_REF:0000118 NCBI chr37:12,503,849...12,536,362
Ensembl chr37:12,503,811...12,532,854 		JBrowse link
G CD2AP CD2 associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14512504) Ensembl
MGI		 PMID:14512504 GO_REF:0000107 NCBI chr12:15,538,215...15,683,619
Ensembl chr12:15,538,356...15,681,011 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within ISO (PMID:10485657) MGI PMID:10485657 NCBI chr 5:15,403,724...15,415,259
Ensembl chr 5:15,403,710...15,415,260 		JBrowse link
G CD8A CD8 subunit alpha involved_in ISO (PMID:17145893) ComplexPortal PMID:17145893 NCBI chr17:38,396,022...38,400,508
Ensembl chr17:38,369,414...38,400,508 		JBrowse link
G CD8B CD8 subunit beta involved_in ISO (PMID:17145893) ComplexPortal PMID:17145893 NCBI chr17:38,342,897...38,358,127 JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18305217) Ensembl
MGI		 PMID:18305217 GO_REF:0000107 NCBI chr26:30,542,276...30,582,479
Ensembl chr26:30,545,311...30,581,964 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874 		JBrowse link
G DENND1B DENN domain containing 1B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:5,008,249...5,267,392
Ensembl chr 7:4,999,430...5,262,630 		JBrowse link
G DLA-DQB1 major histocompatibility complex, class II, DQ beta 1 involved_in ISO (PMID:32341563) UniProt PMID:32341563 NCBI chr12:2,305,307...2,307,711 JBrowse link
G EIF2B1 eukaryotic translation initiation factor 2B subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:6,011,280...6,022,562
Ensembl chr26:6,011,301...6,022,518 		JBrowse link
G EIF2B2 eukaryotic translation initiation factor 2B subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:48,110,521...48,117,175
Ensembl chr 8:48,110,050...48,116,686 		JBrowse link
G EIF2B3 eukaryotic translation initiation factor 2B subunit gamma involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chr15:15,337,421...15,481,427
Ensembl chr15:15,337,483...15,481,425 		JBrowse link
G EIF2B4 eukaryotic translation initiation factor 2B subunit delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:21,321,329...21,326,357
Ensembl chr17:21,321,349...21,326,244 		JBrowse link
G EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:17,038,163...17,047,390
Ensembl chr34:17,038,203...17,046,928 		JBrowse link
G ERMAP erythroblast membrane associated protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:527,726...543,364
Ensembl chr15:526,067...543,638 		JBrowse link
G ERMAP erythroblast membrane associated protein (Scianna blood group) involved_in IEA TreeGrafter GO_REF:0000118
G FCHO1 FCH and mu domain containing endocytic adaptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:45,106,982...45,131,173
Ensembl chr20:45,106,983...45,134,325 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:32610127) Ensembl
MGI		 PMID:32610127 GO_REF:0000107 NCBI chr17:22,340,469...22,364,994
Ensembl chr17:22,341,322...22,361,772 		JBrowse link
G FOXP3 forkhead box P3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10072494), (PMID:11265635) Ensembl
MGI		 PMID:10072494 PMID:11265635 GO_REF:0000107 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758 		JBrowse link
G FYB1 FYN binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:69,729,481...69,876,962
Ensembl chr 4:69,729,462...69,874,845 		JBrowse link
G FYB2 FYN binding protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:52,680,685...52,804,155
Ensembl chr 5:52,680,645...52,801,700 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:68,105,060...68,316,630
Ensembl chr12:68,075,184...68,316,541 		JBrowse link
G GATA3 GATA binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760 		JBrowse link
G HLA-DRB1 MHC class II DLA DRB1 beta chain involved_in ISO (PMID:32341563) UniProt PMID:32341563 NCBI chr12:2,151,409...2,164,564 JBrowse link
G HRAS HRas proto-oncogene, GTPase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21444916) Ensembl
MGI		 PMID:21444916 GO_REF:0000107 NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717 		JBrowse link
G ICOSLG inducible T cell costimulator ligand involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr31:38,084,861...38,094,743 JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (PMID:21444916) MGI PMID:21444916 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
G IRF9 interferon regulatory factor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:4,152,146...4,157,201 JBrowse link
G ITK IL2 inducible T cell kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:52,902,886...52,966,465
Ensembl chr 4:52,902,871...52,966,542 		JBrowse link
G KHDRBS1 KH RNA binding domain containing, signal transduction associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:69,108,822...69,148,067
Ensembl chr 2:69,123,663...69,148,073 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369 		JBrowse link
G LAT linker for activation of T cells involved_in ISO (PMID:25907557) UniProt PMID:25907557 NCBI chr 6:18,458,985...18,462,463
Ensembl chr 6:18,459,061...18,462,694 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:8943371) UniProt PMID:8943371 NCBI chr 2:68,940,816...68,964,585
Ensembl chr 2:68,941,249...68,964,567 		JBrowse link
G LCP2 lymphocyte cytosolic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:41,611,674...41,656,792
Ensembl chr 4:41,611,775...41,656,364 		JBrowse link
G LIME1 Lck interacting transmembrane adaptor 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr24:47,269,922...47,272,288 JBrowse link
G LOC100855640 butyrophilin subfamily 2 member A2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr35:24,251,221...24,265,040
Ensembl chr35:24,251,799...24,262,496 		JBrowse link
G LOC100856021 butyrophilin subfamily 1 member A1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:2,069,335...2,083,333 JBrowse link
G LOC481727 butyrophilin-like protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:1,632,778...1,641,068 JBrowse link
G LOC482199 butyrophilin-like protein 10 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:467,644...474,710 JBrowse link
G LOC482200 butyrophilin-like protein 10 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:496,333...510,770 JBrowse link
G MALT1 MALT1 paracaspase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:17,351,458...17,412,591
Ensembl chr 1:17,354,926...17,403,927 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9064344) Ensembl
MGI		 PMID:9064344 GO_REF:0000107 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998 		JBrowse link
G MOG myelin oligodendrocyte glycoprotein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr35:26,256,311...26,267,357
Ensembl chr35:26,256,489...26,266,832 		JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr 1:116,763,371...116,770,683
Ensembl chr 1:116,757,289...116,772,325 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:8,147,160...8,154,401
Ensembl chr33:8,073,840...8,154,561 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase acts_upstream_of_or_within ISO (PMID:21444916) MGI PMID:21444916 NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788 		JBrowse link
G PDE4B phosphodiesterase 4B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:44,063,145...44,606,070
Ensembl chr 5:44,065,106...44,500,999 		JBrowse link
G PDE4D phosphodiesterase 4D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:45,843,767...47,245,263
Ensembl chr 2:45,846,294...46,949,912 		JBrowse link
G PLCG1 phospholipase C gamma 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15728238) Ensembl
MGI		 PMID:15728238 GO_REF:0000107 NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15728238) Ensembl
MGI		 PMID:15728238 GO_REF:0000107 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049 		JBrowse link
G PRAM1 PML-RARA regulated adaptor molecule 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:53,035,389...53,047,126 JBrowse link
G PRKD2 protein kinase D2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:109,206,400...109,241,529
Ensembl chr 1:109,207,067...109,330,007 		JBrowse link
G PSEN1 presenilin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17698590) Ensembl
MGI		 PMID:17698590 GO_REF:0000107 NCBI chr 8:46,495,551...46,569,532
Ensembl chr 8:46,495,624...46,569,532 		JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (PMID:17698590) MGI PMID:17698590 NCBI chr 7:38,147,157...38,163,023
Ensembl chr 7:38,147,173...38,166,722 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14752163) Ensembl
MGI
TreeGrafter		 PMID:14752163 GO_REF:0000107 GO_REF:0000118 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:9064344) Ensembl
MGI		 PMID:9064344 GO_REF:0000107 NCBI chr27:38,084,976...38,101,552
Ensembl chr27:38,084,980...38,101,937 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124 		JBrowse link
G RBCK1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:20,423,378...20,440,985
Ensembl chr24:20,423,988...20,441,114 		JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,265,836...25,312,417
Ensembl chr 7:25,233,235...25,305,174 		JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:59,881,889...59,943,271
Ensembl chr 9:59,881,966...59,929,341 		JBrowse link
G RFTN1 raftlin, lipid raft linker 1 involved_in ISO (MGI:3850290|PMID:19414744) UniProt PMID:19414744 MGI:3850290 NCBI chr23:26,272,103...26,472,610
Ensembl chr23:26,282,392...26,472,536 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894098) Ensembl
MGI		 PMID:11894098 GO_REF:0000107 NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333 		JBrowse link
G RNF31 ring finger protein 31 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:4,141,501...4,151,999 JBrowse link
G SHB SH2 domain containing adaptor protein B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24645804) Ensembl
MGI		 PMID:24645804 GO_REF:0000107 NCBI chr11:54,189,580...54,329,004
Ensembl chr11:54,189,843...54,329,325 		JBrowse link
G SKAP1 src kinase associated phosphoprotein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:24,412,820...24,700,579
Ensembl chr 9:24,412,820...24,700,734 		JBrowse link
G SLC39A6 solute carrier family 39 member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:54,059,193...54,080,582
Ensembl chr 7:54,059,193...54,080,582 		JBrowse link
G SPN sialophorin involved_in ISO PMID:12496963 ARUK-UCL PMID:12496963 RGD:1358565 NCBI chr 6:17,770,303...17,774,946 JBrowse link
G SPPL3 signal peptide peptidase like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:16,620,236...16,760,616
Ensembl chr26:16,621,455...16,760,623 		JBrowse link
G STK11 serine/threonine kinase 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21487392) Ensembl
MGI		 PMID:21487392 GO_REF:0000107 NCBI chr20:57,558,966...57,579,163
Ensembl chr20:57,559,424...57,579,118 		JBrowse link
G STOML2 stomatin like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18641330) Ensembl
UniProt		 PMID:18641330 GO_REF:0000107 NCBI chr11:51,675,963...51,679,313
Ensembl chr11:51,675,963...51,679,199 		JBrowse link
G TEC tec protein tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:43,978,964...44,111,256
Ensembl chr13:43,978,573...44,062,795 		JBrowse link
G THEMIS thymocyte selection associated involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:66,363,172...66,540,272
Ensembl chr 1:66,363,125...66,540,327 		JBrowse link
G THEMIS2 thymocyte selection associated family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22732588) Ensembl
MGI
TreeGrafter		 PMID:22732588 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:72,465,719...72,501,962
Ensembl chr 2:72,464,026...72,502,928 		JBrowse link
G THY1 Thy-1 cell surface antigen involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:14,503,902...14,509,113
Ensembl chr 5:14,503,902...14,509,113 		JBrowse link
G TNFRSF21 TNF receptor superfamily member 21 involved_in ISO (MGI:2137821|PMID:11485735) UniProt PMID:11485735 MGI:2137821 NCBI chr12:15,343,953...15,408,230 JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:31,674,242...31,689,160
Ensembl chr18:31,675,391...31,688,641 		JBrowse link
G TXK TXK tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:43,911,881...43,977,499
Ensembl chr13:43,914,534...43,976,655 		JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chr10:41,470,073...41,470,738
Ensembl chr10:41,470,073...41,470,738 		JBrowse link
G VTCN1 V-set domain containing T cell activation inhibitor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:54,533,153...54,587,262
Ensembl chr17:54,536,026...54,587,110 		JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:42,764,184...42,914,591
Ensembl chr27:42,765,181...42,912,806 		JBrowse link
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9208839) Ensembl
MGI		 PMID:9208839 GO_REF:0000107 NCBI chr10:44,887,416...44,913,845
Ensembl chr10:44,887,433...44,900,071 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:4,972,369...4,984,218
Ensembl chr15:4,972,956...4,980,371 		JBrowse link
G ZNF683 zinc finger protein 683 involved_in ISO (PMID:26179882) UniProt PMID:26179882 NCBI chr 2:73,656,842...73,667,621
Ensembl chr 2:73,658,525...73,667,605 		JBrowse link
TIRAP-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIRAP TIR domain containing adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:8,222,217...8,237,595
Ensembl chr 5:8,221,794...8,226,074 		JBrowse link
toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10549626) Ensembl
MGI		 PMID:10549626 GO_REF:0000107 NCBI chr  X:121,853,340...121,862,582
Ensembl chr  X:121,819,432...121,862,576 		JBrowse link
G LGALS9 galectin 9 NOT|involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15220916) Ensembl
MGI		 PMID:15220916 GO_REF:0000107 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:9,977,463...10,095,363
Ensembl chr28:9,978,900...10,095,284 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11894098) MGI
Ensembl		 PMID:11894098 GO_REF:0000107 NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333 		JBrowse link
G TLR2 toll like receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241 		JBrowse link
G TLR2 toll like receptor 2 involved_in IEA Ensembl GO_REF:0000107
G TNIP2 TNFAIP3 interacting protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:61,511,676...61,535,480 JBrowse link
toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule involved_in ISO (MGI:5645190|PMID:25158758) UniProt PMID:25158758 MGI:5645190 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087 		JBrowse link
G COLEC12 collectin subfamily member 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:67,192,191...67,373,524
Ensembl chr 7:67,193,626...67,372,755 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393 		JBrowse link
G LGALS9 galectin 9 involved_in ISO PMID:25158758 UniProt PMID:25158758 RGD:10054077 NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:10,385,393...10,396,734
Ensembl chr26:10,385,447...10,396,733 		JBrowse link
G RFTN1 raftlin, lipid raft linker 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21266579) MGI
Ensembl		 PMID:21266579 GO_REF:0000107 NCBI chr23:26,272,103...26,472,610
Ensembl chr23:26,282,392...26,472,536 		JBrowse link
G SCARA3 scavenger receptor class A member 3 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chr25:29,891,099...29,966,846
Ensembl chr25:29,917,335...29,968,076 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISO (MGI:5913054|PMID:28098138) UniProt PMID:28098138 MGI:5913054 NCBI chr 5:31,534,470...31,551,441
Ensembl chr 5:31,534,226...31,549,175 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in ISO (PMID:12471095) UniProt PMID:12471095 NCBI chr20:54,948,237...54,961,996
Ensembl chr20:54,959,525...54,961,780 		JBrowse link
G TLR3 toll like receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:44,617,012...44,633,591
Ensembl chr16:44,550,846...44,653,247 		JBrowse link
G TNF tumor necrosis factor involved_in ISO PMID:25158758 UniProt PMID:25158758 RGD:10054077 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:61,511,676...61,535,480 JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:49,826,044...49,835,417
Ensembl chr18:49,826,026...49,882,461 		JBrowse link
toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:35,790,505...35,792,967 JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:12,964,670...13,001,557
Ensembl chr28:12,965,479...13,001,512 		JBrowse link
G ECSIT ECSIT signaling integrator involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:49,848,848...49,867,075
Ensembl chr20:49,848,912...49,867,066 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 acts_upstream_of_or_within ISO (PMID:10549626) MGI PMID:10549626 NCBI chr  X:121,853,340...121,862,582
Ensembl chr  X:121,819,432...121,862,576 		JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:8,133,987...8,197,009
Ensembl chr20:8,134,970...8,196,910 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:106,875,016...106,879,065
Ensembl chr 1:106,875,118...106,879,065 		JBrowse link
G LGALS9 galectin 9 NOT|involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391 		JBrowse link
G LY96 lymphocyte antigen 96 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr29:22,493,757...22,515,147
Ensembl chr29:22,493,896...22,515,117 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:49,669,849...49,740,039
Ensembl chr12:49,672,389...49,739,850 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534 		JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29624734) Ensembl
MGI		 PMID:29624734 GO_REF:0000107 NCBI chr 9:20,407,296...20,414,094
Ensembl chr 9:20,407,281...20,414,056 		JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI
TreeGrafter		 PMID:18261938 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:14,100,203...14,103,453
Ensembl chr 8:14,100,671...14,103,433 		JBrowse link
G NMI N-myc and STAT interactor involved_in ISO (MGI:6099204|PMID:29038465) UniProt PMID:29038465 MGI:6099204 NCBI chr19:52,541,796...52,555,043
Ensembl chr19:52,541,981...52,553,574 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:10,385,393...10,396,734
Ensembl chr26:10,385,447...10,396,733 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:9,977,463...10,095,363
Ensembl chr28:9,978,900...10,095,284 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894098) Ensembl
MGI		 PMID:11894098 GO_REF:0000107 NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333 		JBrowse link
G S100A14 S100 calcium binding protein A14 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:43,443,073...43,446,416
Ensembl chr 7:43,444,396...43,446,287 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISO (MGI:5913054|PMID:28098138) UniProt PMID:28098138 MGI:5913054 NCBI chr 5:31,534,470...31,551,441
Ensembl chr 5:31,534,226...31,549,175 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:7,169,664...7,208,890
Ensembl chr10:7,168,007...7,208,899 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in ISO (PMID:12471095) UniProt PMID:12471095 NCBI chr20:54,948,237...54,961,996
Ensembl chr20:54,959,525...54,961,780 		JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 involved_in ISO (PMID:28630139) UniProt PMID:28630139 NCBI chr11:5,312,383...5,313,099
Ensembl chr11:5,312,383...5,313,099 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:8,222,217...8,237,595
Ensembl chr 5:8,221,794...8,226,074 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25549946) Ensembl
MGI
TreeGrafter		 PMID:25549946 GO_REF:0000107 GO_REF:0000118 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G TMEM126A transmembrane protein 126A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25549946) Ensembl
MGI		 PMID:25549946 GO_REF:0000107 NCBI chr21:13,787,074...13,795,779
Ensembl chr21:13,787,123...13,795,739 		JBrowse link
G TNIP3 TNFAIP3 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:18,857,719...18,960,760
Ensembl chr19:18,853,168...18,960,760 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:70,739,389...70,794,448
Ensembl chr 8:70,739,417...70,790,645 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:31,674,242...31,689,160
Ensembl chr18:31,675,391...31,688,641 		JBrowse link
G TRIL TLR4 interactor with leucine rich repeats involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:41,999,558...42,004,418
Ensembl chr14:42,001,920...42,004,397 		JBrowse link
toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIRAP TIR domain containing adaptor protein NOT|involved_in ISO (MGI:3531416|PMID:12447442) BHF-UCL PMID:12447442 MGI:3531416 NCBI chr 5:8,222,217...8,237,595
Ensembl chr 5:8,221,794...8,226,074 		JBrowse link
G TLR5 toll like receptor 5 involved_in ISO (PMID:17128265) BHF-UCL PMID:17128265 NCBI chr38:23,700,323...23,705,628
Ensembl chr38:23,702,033...23,705,314 		JBrowse link
toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:9,977,463...10,095,363
Ensembl chr28:9,978,900...10,095,284 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISO (MGI:5913054|PMID:28098138) UniProt PMID:28098138 MGI:5913054 NCBI chr 5:31,534,470...31,551,441
Ensembl chr 5:31,534,226...31,549,175 		JBrowse link
G TLR7 toll like receptor 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:9,331,243...9,360,461
Ensembl chr  X:9,314,815...9,359,603 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:49,826,044...49,835,417
Ensembl chr18:49,826,026...49,882,461 		JBrowse link
toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534 		JBrowse link
G TLR8 toll like receptor 8 involved_in ISO (PMID:12032557), (PMID:24942581), (PMID:33718825) UniProt PMID:12032557 PMID:24942581 PMID:33718825 NCBI chr  X:9,381,159...9,399,938 JBrowse link
toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPG5 ectopic P-granules 5 autophagy tethering factor acts_upstream_of_positive_effect
involved_in		 ISO
IEA		 (PMID:29130391) UniProt
Ensembl		 PMID:29130391 GO_REF:0000107 NCBI chr 7:45,215,232...45,318,736
Ensembl chr 7:45,215,324...45,314,630 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:39,497,313...39,608,120
Ensembl chr15:39,536,290...39,608,116 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:9,977,463...10,095,363
Ensembl chr28:9,978,900...10,095,284 		JBrowse link
G TLR9 toll like receptor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in ISO (MGI:3656197|PMID:16633345) UniProt PMID:16633345 MGI:3656197 NCBI chr 3:61,511,676...61,535,480 JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:49,826,044...49,835,417
Ensembl chr18:49,826,026...49,882,461 		JBrowse link
toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP3B1 adaptor related protein complex 3 subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20847273) Ensembl
MGI		 PMID:20847273 GO_REF:0000107 NCBI chr 3:28,481,974...28,748,095
Ensembl chr 3:28,481,038...28,751,258 		JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:62,712,937...62,723,852
Ensembl chr 6:62,712,971...62,722,368 		JBrowse link
G CD86 CD86 molecule acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30990796) Ensembl
MGI		 PMID:30990796 GO_REF:0000107 NCBI chr18:51,366,719...51,374,411
Ensembl chr18:51,368,352...51,373,748 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 ISO RGD PMID:27832756 RGD:34888235 NCBI chr10:8,683,541...8,730,757
Ensembl chr10:8,684,242...8,729,268 		JBrowse link
G LOC119876150 toll-like receptor 6 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118
G LOC491698 uncharacterized LOC491698 involved_in IEA InterPro GO_REF:0000002 NCBI chr28:40,902,770...40,905,628 JBrowse link
G LRRC19 leucine rich repeat containing 19 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19679103) Ensembl
MGI		 PMID:19679103 GO_REF:0000107 NCBI chr11:45,181,709...45,188,106
Ensembl chr11:45,181,602...45,186,893 		JBrowse link
G LY96 lymphocyte antigen 96 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:22,493,757...22,515,147
Ensembl chr29:22,493,896...22,515,117 		JBrowse link
G MAPKAPK2 MAPK activated protein kinase 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:5,873,088...5,903,484
Ensembl chr 7:5,814,201...5,902,220 		JBrowse link
G MAPKAPK3 MAPK activated protein kinase 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:38,731,492...38,759,000
Ensembl chr20:38,732,397...38,758,494 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:8,147,160...8,154,401
Ensembl chr33:8,073,840...8,154,561 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049 		JBrowse link
G RPS6KA3 ribosomal protein S6 kinase A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:15,991,623...16,079,689
Ensembl chr  X:15,998,172...16,074,749 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in ISO (PMID:12471095) UniProt PMID:12471095 NCBI chr20:54,948,237...54,961,996
Ensembl chr20:54,959,525...54,961,780 		JBrowse link
G TIFAB TIFA inhibitor involved_in
acts_upstream_of_negative_effect		 IEA
ISO		 (PMID:26458771) Ensembl
MGI		 PMID:26458771 GO_REF:0000107 NCBI chr11:23,492,317...23,495,825
Ensembl chr11:23,492,867...23,493,352 		JBrowse link
G TLR1 toll like receptor 1 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:16973131 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1643119 NCBI chr 3:73,504,359...73,544,822
Ensembl chr 3:73,539,715...73,544,624 		JBrowse link
G TLR10 toll like receptor 10 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 3:73,561,596...73,589,286
Ensembl chr 3:73,568,321...73,570,744 		JBrowse link
G TLR2 toll like receptor 2 involved_in ISO
IBA
IEA		 RGD
GO_Central
TreeGrafter
UniProt
Ensembl
InterPro		 PMID:16973131 PMID:18353287 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 RGD:1643119 RGD:5684896 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241 		JBrowse link
G TLR2 toll like receptor 2 involved_in IEA InterPro
TreeGrafter
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118
G TLR3 toll like receptor 3 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:16973131 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1643119 NCBI chr16:44,617,012...44,633,591
Ensembl chr16:44,550,846...44,653,247 		JBrowse link
G TLR4 toll like receptor 4 involved_in ISO
IEA		 RGD
Ensembl
InterPro		 PMID:16973131 GO_REF:0000002 GO_REF:0000107 RGD:1643119 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G TLR5 toll like receptor 5 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr38:23,700,323...23,705,628
Ensembl chr38:23,702,033...23,705,314 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISO
IEA		 RGD
TreeGrafter
InterPro		 PMID:16973131 PMID:18353287 GO_REF:0000002 GO_REF:0000118 RGD:1643119 RGD:5684896 NCBI chr 3:73,504,357...73,523,964
Ensembl chr 3:73,520,706...73,523,099 		JBrowse link
G TLR7 toll like receptor 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:9,331,243...9,360,461
Ensembl chr  X:9,314,815...9,359,603 		JBrowse link
G TLR8 toll like receptor 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:9,381,159...9,399,938 JBrowse link
G TLR9 toll like receptor 9 involved_in ISO
IEA
IBA		 RGD
TreeGrafter
GO_Central
Ensembl		 PMID:16973131 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:1643119 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:70,739,389...70,794,448
Ensembl chr 8:70,739,417...70,790,645 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16415873) InterPro
MGI
Ensembl		 PMID:16415873 GO_REF:0000002 GO_REF:0000107 NCBI chr18:49,826,044...49,835,417
Ensembl chr18:49,826,026...49,882,461 		JBrowse link
toll-like receptor TLR1:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISO (MGI:5913054|PMID:28098138) UniProt PMID:28098138 MGI:5913054 NCBI chr 5:31,534,470...31,551,441
Ensembl chr 5:31,534,226...31,549,175 		JBrowse link
toll-like receptor TLR6:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TLR2 toll like receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241 		JBrowse link
G TLR2 toll like receptor 2 involved_in IEA Ensembl GO_REF:0000107
G TLR6 toll like receptor 6 involved_in ISO (PMID:23626692) ComplexPortal PMID:23626692 NCBI chr 3:73,504,357...73,523,964
Ensembl chr 3:73,520,706...73,523,099 		JBrowse link
TRAM-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCE protein kinase C epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:47,976,929...48,464,614
Ensembl chr10:47,976,768...48,535,296 		JBrowse link
G RAB11FIP2 RAB11 family interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:28,415,139...28,457,215
Ensembl chr28:28,415,639...28,457,286 		JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 involved_in ISO (PMID:19412184)
(PMID:22685567)		 UniProt PMID:19412184 PMID:22685567 NCBI chr11:5,312,383...5,313,099
Ensembl chr11:5,312,383...5,313,099 		JBrowse link
TRIF-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD274 CD274 molecule involved_in ISO (PMID:36232715) UniProt PMID:36232715 NCBI chr 1:93,461,735...93,605,772
Ensembl chr 1:93,585,518...93,603,522 		JBrowse link
G CD300LF CD300 molecule like family member f involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chr 9:5,700,915...5,714,868 JBrowse link
G CD40 CD40 molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr24:33,352,992...33,383,488
Ensembl chr24:33,372,930...33,383,301 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:106,875,016...106,879,065
Ensembl chr 1:106,875,118...106,879,065 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr20:54,948,237...54,961,996
Ensembl chr20:54,959,525...54,961,780 		JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr11:5,312,383...5,313,099
Ensembl chr11:5,312,383...5,313,099 		JBrowse link
G TLR4 toll like receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISO (MGI:4438693|PMID:20037584) ARUK-UCL PMID:20037584 MGI:4438693 NCBI chr 3:73,504,357...73,523,964
Ensembl chr 3:73,520,706...73,523,099 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    immune system process 2495
      activation of immune response 533
        immune response-activating signaling pathway 470
          immune response-activating cell surface receptor signaling pathway + 287
          innate immune response-activating signaling pathway + 277
Path 2
Term Annotations click to browse term
  biological_process 17917
    biological regulation 12438
      regulation of biological process 12078
        positive regulation of biological process 6606
          positive regulation of response to stimulus 2438
            positive regulation of immune response 721
              activation of immune response 533
                immune response-activating signaling pathway 470
                  immune response-activating cell surface receptor signaling pathway + 287
                  innate immune response-activating signaling pathway + 277
paths to the root