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ONTOLOGY REPORT - ANNOTATIONS

Term:immune response-activating signaling pathway
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Accession:GO:0002757 term browser browse the term
Definition:The series of molecular signals generated by a ligand binding to its receptor that lead to the activation or perpetuation of an immune response.
Synonyms:exact_synonym: immune response-activating signal transduction

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immune response-activating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zc3h12a zinc finger CCCH-type containing 12A involved_in ISO (PMID:19909337) UniProt PMID:19909337 NCBI chrNW_004955452:15,306,398...15,314,959
Ensembl chrNW_004955452:15,305,775...15,314,959 		JBrowse link
antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISO (PMID:10587647) UniProt PMID:10587647 NCBI chrNW_004955484:2,223,306...2,258,444
Ensembl chrNW_004955484:2,227,337...2,260,565 		JBrowse link
G Cd19 CD19 molecule involved_in ISO (PMID:1373518) UniProt PMID:1373518 NCBI chrNW_004955493:6,540,160...6,544,077 JBrowse link
G Lax1 lymphocyte transmembrane adaptor 1 acts_upstream_of_or_within ISO (PMID:15843560) MGI PMID:15843560 NCBI chrNW_004955406:39,656,549...39,667,448
Ensembl chrNW_004955406:39,656,128...39,670,244 		JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in ISO (PMID:15214043) BHF-UCL PMID:15214043 NCBI chrNW_004955559:1,695,960...1,700,246
Ensembl chrNW_004955559:1,695,960...1,700,244 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:23728777) MGI PMID:23728777 NCBI chrNW_004955427:3,350,174...3,358,609
Ensembl chrNW_004955427:3,350,174...3,360,379 		JBrowse link
B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:11120811), (PMID:19228876) MGI PMID:11120811 PMID:19228876 NCBI chrNW_004955513:652,048...799,182
Ensembl chrNW_004955513:653,252...799,239 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISO (PMID:9020138) UniProt PMID:9020138 NCBI chrNW_004955484:2,223,306...2,258,444
Ensembl chrNW_004955484:2,227,337...2,260,565 		JBrowse link
G Bcl2 BCL2 apoptosis regulator involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485 		JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:876631)
(PMID:23555801) 		UniProt
ARUK-UCL		 PMID:876631 PMID:23555801 NCBI chrNW_004955403:52,825,397...52,874,007
Ensembl chrNW_004955403:52,832,604...52,874,264 		JBrowse link
G Blnk B cell linker involved_in ISO (PMID:9697839)
(PMID:11606584) 		UniProt
ARUK-UCL		 PMID:9697839 PMID:11606584 NCBI chrNW_004955507:2,398,694...2,466,461
Ensembl chrNW_004955507:2,397,400...2,466,788 		JBrowse link
G Btk Bruton tyrosine kinase involved_in ISO (PMID:15509800) ARUK-UCL PMID:15509800 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120 		JBrowse link
G Cd19 CD19 molecule acts_upstream_of_or_within
involved_in 		ISO (PMID:9254656)
(PMID:23499492) 		MGI
UniProt		 PMID:9254656 PMID:23499492 NCBI chrNW_004955493:6,540,160...6,544,077 JBrowse link
G Cd38 CD38 molecule involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004955480:8,177,178...8,218,483
Ensembl chrNW_004955480:8,178,473...8,217,643 		JBrowse link
G Cd79a CD79a molecule acts_upstream_of_or_within
involved_in 		ISO (PMID:1373499), (PMID:8626447)
(PMID:1439759), (PMID:8626447) 		MGI
UniProt		 PMID:1373499 PMID:1439759 PMID:8626447 NCBI chrNW_004955555:961,522...965,605
Ensembl chrNW_004955555:961,522...965,605 		JBrowse link
G Cd79b CD79b molecule involved_in
acts_upstream_of_or_within 		ISO (PMID:8626447)
(PMID:1373499), (PMID:8626447) 		MGI PMID:1373499 PMID:8626447 NCBI chrNW_004955478:7,909,353...7,912,814
Ensembl chrNW_004955478:7,909,153...7,913,166 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004955457:11,028,707...11,034,898
Ensembl chrNW_004955457:11,028,698...11,073,460 		JBrowse link
G Fcrl5 Fc receptor like 5 acts_upstream_of ISO (PMID:23509253) MGI PMID:23509253 NCBI chrNW_004955468:9,434,654...9,464,907
Ensembl chrNW_004955468:9,435,804...9,465,024 		JBrowse link
G Grb2 growth factor receptor bound protein 2 involved_in ISO (PMID:9199344) MGI PMID:9199344 NCBI chrNW_004955553:2,186,590...2,258,964
Ensembl chrNW_004955553:2,186,590...2,259,456 		JBrowse link
G Klhl6 kelch like family member 6 involved_in ISO (PMID:16166635) UniProt PMID:16166635 NCBI chrNW_004955420:23,813,482...23,877,886 JBrowse link
G Lat2 linker for activation of T cells family member 2 involved_in ISO (PMID:12514734) HGNC-UCL PMID:12514734 NCBI chrNW_004955456:13,674,190...13,688,611 JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:7499277) MGI PMID:7499277 NCBI chrNW_004955452:10,608,317...10,632,310
Ensembl chrNW_004955452:10,608,318...10,632,310 		JBrowse link
G Lime1 Lck interacting transmembrane adaptor 1 acts_upstream_of_or_within ISO (PMID:16249387) MGI PMID:16249387 NCBI chrNW_004955528:490,319...492,943
Ensembl chrNW_004955528:490,471...491,688 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:23509253)
(PMID:7499277) 		MGI PMID:7499277 PMID:23509253 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 acts_upstream_of_or_within ISO (PMID:9254656) MGI PMID:9254656 NCBI chrNW_004955442:17,284,232...17,380,026
Ensembl chrNW_004955442:17,284,232...17,380,020 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (PMID:18955699) UniProt PMID:18955699 NCBI chrNW_004955418:22,537,388...22,701,434
Ensembl chrNW_004955418:22,537,285...22,701,434 		JBrowse link
G Ms4a1 membrane spanning 4-domains A1 involved_in ISO (PMID:18474602) UniProt PMID:18474602 NCBI chrNW_004955511:5,252,934...5,263,961
Ensembl chrNW_004955511:5,258,341...5,267,113 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004955458:1,733,799...1,785,591
Ensembl chrNW_004955458:1,733,883...1,784,182 		JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 acts_upstream_of_or_within
involved_in 		ISO (PMID:15143214) MGI
HGNC-UCL		 PMID:15143214 NCBI chrNW_004955413:27,865,672...27,893,793
Ensembl chrNW_004955413:27,866,271...27,893,844 		JBrowse link
G Nfatc2 nuclear factor of activated T cells 2 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004955445:7,035,876...7,153,199
Ensembl chrNW_004955445:7,035,876...7,153,237 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:17367755) MGI PMID:17367755 NCBI chrNW_004955496:5,842,734...5,950,995
Ensembl chrNW_004955496:5,842,600...5,927,885 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:17367755) MGI PMID:17367755 NCBI chrNW_004955409:25,691,673...25,695,151
Ensembl chrNW_004955409:25,691,534...25,697,520 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:17367755) MGI PMID:17367755 NCBI chrNW_004955427:3,350,174...3,358,609
Ensembl chrNW_004955427:3,350,174...3,360,379 		JBrowse link
G Plcg2 phospholipase C gamma 2 involved_in ISO (PMID:11606584)
(PMID:10925250)
(PMID:15509800) 		ARUK-UCL
UniProt		 PMID:10925250 PMID:11606584 PMID:15509800 NCBI chrNW_004955522:4,352,890...4,480,735
Ensembl chrNW_004955522:4,358,233...4,468,986 		JBrowse link
G Plekha1 pleckstrin homology domain containing A1 involved_in ISO (PMID:12101241) UniProt PMID:12101241 NCBI chrNW_004955477:659,640...730,394
Ensembl chrNW_004955477:659,641...732,627 		JBrowse link
G Prkcb protein kinase C beta involved_in ISO (PMID:12118249) UniProt PMID:12118249 NCBI chrNW_004955493:2,395,494...2,710,522
Ensembl chrNW_004955493:2,395,109...2,710,934 		JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within ISO (PMID:9254656)
(PMID:23509253) 		MGI PMID:9254656 PMID:23509253 NCBI chrNW_004955413:4,525,954...4,547,177
Ensembl chrNW_004955413:4,525,954...4,547,177 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within
involved_in 		ISO (PMID:7499277)
(PMID:8692271)
(PMID:9254656) 		MGI
UniProt		 PMID:7499277 PMID:8692271 PMID:9254656 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Rftn1 raftlin, lipid raft linker 1 involved_in ISO (PMID:12805216) UniProt PMID:12805216 NCBI chrNW_004955430:8,605,057...8,801,187
Ensembl chrNW_004955430:8,603,401...8,779,896 		JBrowse link
G Sh2b2 SH2B adaptor protein 2 involved_in
acts_upstream_of_or_within 		ISO (PMID:9233773)
(PMID:10872802) 		UniProt
MGI		 PMID:9233773 PMID:10872802 NCBI chrNW_004955456:15,253,711...15,265,874
Ensembl chrNW_004955456:15,253,856...15,265,845 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in ISO (PMID:24043312) MGI PMID:24043312 NCBI chrNW_004955441:6,649,895...6,724,271
Ensembl chrNW_004955441:6,646,385...6,713,028 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within 		ISO (PMID:15509800)
(PMID:9199344)
(PMID:7499277), (PMID:8626447) 		ARUK-UCL
MGI		 PMID:7499277 PMID:8626447 PMID:9199344 PMID:15509800 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581 		JBrowse link
G Tec tec protein tyrosine kinase involved_in ISO (PMID:10518561) UniProt PMID:10518561 NCBI chrNW_004955443:339,678...474,029
Ensembl chrNW_004955443:340,940...476,702 		JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004955435:11,326,910...11,599,043
Ensembl chrNW_004955435:11,326,910...11,599,043 		JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISO (PMID:15294986) AgBase PMID:15294986 NCBI chrNW_004955418:73,736...75,345
Ensembl chrNW_004955418:73,897...75,224 		JBrowse link
G Fcn1 ficolin 1 involved_in ISO (PMID:21037097) UniProt PMID:21037097 NCBI chrNW_004955513:3,690,550...3,697,785
Ensembl chrNW_004955513:3,687,232...3,698,673 		JBrowse link
G Mbl2 mannose binding lectin 2 involved_in ISO (PMID:22966085) ComplexPortal PMID:22966085 NCBI chrNW_004955425:7,704,371...7,708,951
Ensembl chrNW_004955425:7,702,137...7,709,006 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO (PMID:19358895) ARUK-UCL PMID:19358895 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581 		JBrowse link
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258 		JBrowse link
cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:32911482), (PMID:32912999), (PMID:33542149), (PMID:35322803), (PMID:35438208), (PMID:35460603), (PMID:39322678)
(PMID:39322678) 		UniProt PMID:32911482 PMID:32912999 PMID:33542149 PMID:35322803 PMID:35438208 More... NCBI chrNW_004955493:8,593,104...8,607,297 JBrowse link
G Ddx41 DEAD-box helicase 41 involved_in ISO (PMID:35613581) UniProt PMID:35613581 NCBI chrNW_004955408:29,748,091...29,753,610
Ensembl chrNW_004955408:29,744,751...29,754,497 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (PMID:25636800), (PMID:30842659), (PMID:30842662), (PMID:35388221), (PMID:37832545)
(PMID:37832545) 		UniProt PMID:25636800 PMID:30842659 PMID:30842662 PMID:35388221 PMID:37832545 NCBI chrNW_004955418:1,091,022...1,097,064
Ensembl chrNW_004955418:1,083,613...1,100,448 		JBrowse link
complement component C5a signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blvra biliverdin reductase A acts_upstream_of_or_within ISO (PMID:30952817) MGI PMID:30952817 NCBI chrNW_004955460:129,077...167,345
Ensembl chrNW_004955460:125,854...167,506 		JBrowse link
G C5ar1 complement C5a receptor 1 involved_in ISO (PMID:10571060) UniProt PMID:10571060 NCBI chrNW_004955574:1,221,942...1,229,634
Ensembl chrNW_004955574:1,221,187...1,231,655 		JBrowse link
complement receptor mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:19162005) BHF-UCL PMID:19162005 NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904 		JBrowse link
G C3 complement C3 involved_in ISO (PMID:22632727) ARUK-UCL PMID:22632727 NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697 		JBrowse link
G C3ar1 complement C3a receptor 1 involved_in ISO (PMID:10571060) UniProt PMID:10571060 NCBI chrNW_004955413:6,707,003...6,715,689
Ensembl chrNW_004955413:6,707,689...6,715,689 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:15907827), (PMID:19135435) UniProt PMID:15907827 PMID:19135435 NCBI chrNW_004955483:2,501,751...2,552,855
Ensembl chrNW_004955483:2,502,345...2,552,689 		JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (PMID:22632727) ARUK-UCL PMID:22632727 NCBI chrNW_004955493:8,116,886...8,160,806
Ensembl chrNW_004955493:8,116,834...8,260,759 		JBrowse link
G Rgcc regulator of cell cycle involved_in ISO (PMID:19162005) BHF-UCL PMID:19162005 NCBI chrNW_004955518:4,788,857...4,800,273
Ensembl chrNW_004955518:4,788,656...4,801,204 		JBrowse link
cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpk1 alpha kinase 1 involved_in ISO (PMID:28222186), (PMID:28877472), (PMID:30111836)
(PMID:30111836) 		UniProt PMID:28222186 PMID:28877472 PMID:30111836 NCBI chrNW_004955457:14,325,278...14,444,368
Ensembl chrNW_004955457:14,325,281...14,379,937 		JBrowse link
G Becn1 beclin 1 involved_in ISO (PMID:34796041) UniProt PMID:34796041 NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730 		JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:23258413) UniProt PMID:23258413 NCBI chrNW_004955493:8,593,104...8,607,297 JBrowse link
G Ddx3x DEAD-box helicase 3 X-linked involved_in ISO (PMID:23478265) UniProt PMID:23478265 NCBI chrNW_004955565:1,387,043...1,403,624
Ensembl chrNW_004955565:1,386,973...1,404,220 		JBrowse link
G Dhx58 DExH-box helicase 58 involved_in ISO (PMID:19211564) UniProt PMID:19211564 NCBI chrNW_004955451:16,186,263...16,191,928
Ensembl chrNW_004955451:16,185,510...16,191,719 		JBrowse link
G Ipo5 importin 5 involved_in ISO (PMID:31340999) UniProt PMID:31340999 NCBI chrNW_004955404:12,416,755...12,480,281
Ensembl chrNW_004955404:12,416,755...12,459,452 		JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO (PMID:8524823) UniProt PMID:8524823 NCBI chrNW_004955559:1,223,986...1,228,671
Ensembl chrNW_004955559:1,224,874...1,228,624 		JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO (PMID:21931555) UniProt PMID:21931555 NCBI chrNW_004955476:11,442,781...11,445,706
Ensembl chrNW_004955476:11,443,272...11,445,657 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:16125763), (PMID:20451243) UniProt PMID:16125763 PMID:20451243 NCBI chrNW_004955415:14,691,918...14,704,782
Ensembl chrNW_004955415:14,695,438...14,703,672 		JBrowse link
G Rigi RNA sensor RIG-I involved_in ISO (PMID:19576794) UniProt PMID:19576794 NCBI chrNW_004955472:3,093,895...3,135,524
Ensembl chrNW_004955472:3,093,939...3,133,987 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (PMID:23910378), (PMID:35388221) UniProt PMID:23910378 PMID:35388221 NCBI chrNW_004955418:1,091,022...1,097,064
Ensembl chrNW_004955418:1,083,613...1,100,448 		JBrowse link
G Tbk1 TANK binding kinase 1 involved_in ISO (PMID:29441066) UniProt PMID:29441066 NCBI chrNW_004955458:11,210,120...11,263,632
Ensembl chrNW_004955458:11,211,398...11,263,867 		JBrowse link
G Tifa TRAF interacting protein with forkhead associated domain involved_in ISO (PMID:26068852), (PMID:28222186), (PMID:28877472), (PMID:30111836) UniProt PMID:26068852 PMID:28222186 PMID:28877472 PMID:30111836 NCBI chrNW_004955457:14,444,811...14,460,168
Ensembl chrNW_004955457:14,444,814...14,450,767 		JBrowse link
G Traf3ip3 TRAF3 interacting protein 3 involved_in ISO (PMID:31390091) UniProt PMID:31390091 NCBI chrNW_004955489:2,442,319...2,468,683
Ensembl chrNW_004955489:2,440,455...2,464,700 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:20501938), (PMID:23015697) UniProt PMID:20501938 PMID:23015697 NCBI chrNW_004955422:9,925,765...9,950,354
Ensembl chrNW_004955422:9,932,680...9,949,100 		JBrowse link
G Trim25 tripartite motif containing 25 involved_in ISO (PMID:17392790) UniProt PMID:17392790 NCBI chrNW_004955451:5,918,287...5,934,252
Ensembl chrNW_004955451:5,918,287...5,934,258 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in ISO (PMID:22607805) UniProt PMID:22607805 NCBI chrNW_004955481:1,752,778...1,805,700
Ensembl chrNW_004955481:1,752,778...1,808,583 		JBrowse link
endolysosomal toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Washc4 WASH complex subunit 4 acts_upstream_of_or_within ISO (PMID:33749590) MGI PMID:33749590 NCBI chrNW_004955405:39,451,423...39,499,295
Ensembl chrNW_004955405:39,451,404...39,499,295 		JBrowse link
Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:14764707) MGI PMID:14764707 NCBI chrNW_004955468:12,971,931...12,975,206
Ensembl chrNW_004955468:12,971,931...12,975,206 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:16272347) UniProt PMID:16272347 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142 		JBrowse link
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer2 Fc fragment of IgE receptor II involved_in ISO (PMID:7544003) BHF-UCL PMID:7544003 NCBI chrNW_004955563:1,587,471...1,596,707
Ensembl chrNW_004955563:1,587,396...1,596,063 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:7544003) BHF-UCL PMID:7544003 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
G Myo1g myosin IG involved_in ISO (PMID:23038771) UniProt PMID:23038771 NCBI chrNW_004955456:7,289,097...7,300,551
Ensembl chrNW_004955456:7,288,373...7,302,430 		JBrowse link
G Nos2 nitric oxide synthase 2 involved_in ISO (PMID:7544003) BHF-UCL PMID:7544003 NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961 		JBrowse link
immune response-activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag6 BAG cochaperone 6 involved_in ISO (PMID:18852879) UniProt PMID:18852879 NCBI chrNW_004955437:176,848...188,243
Ensembl chrNW_004955437:176,797...188,003 		JBrowse link
G Ncr3 natural cytotoxicity triggering receptor 3 involved_in ISO (PMID:18852879) UniProt PMID:18852879 NCBI chrNW_004955437:130,360...134,751 JBrowse link
inflammasome-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elp6 elongator acetyltransferase complex subunit 6 acts_upstream_of_or_within ISO (PMID:30097576) MGI PMID:30097576 NCBI chrNW_004955420:24,795,416...24,807,790
Ensembl chrNW_004955420:24,795,496...24,811,134 		JBrowse link
innate immune response-activating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr4 toll like receptor 4 ISO RGD PMID:19226379 RGD:2312509 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifih1 interferon induced with helicase C domain 1 involved_in ISO (PMID:17600090), (PMID:33727702)
(PMID:19211564) 		UniProt PMID:17600090 PMID:19211564 PMID:33727702 NCBI chrNW_004955449:11,538,869...11,596,502
Ensembl chrNW_004955449:11,538,889...11,593,349 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in ISO (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chrNW_004955482:9,339,174...9,359,266 JBrowse link
MyD88-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrfip2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chrNW_004955421:3,938,054...4,066,701
Ensembl chrNW_004955421:3,938,054...4,066,060 		JBrowse link
MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) BHF-UCL PMID:16148103 NCBI chrNW_004955403:3,062,724...3,073,419
Ensembl chrNW_004955403:3,063,133...3,073,419 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor acts_upstream_of_or_within ISO (PMID:12719478)
(PMID:12872135)
(PMID:14764662) 		MGI PMID:12719478 PMID:12872135 PMID:14764662 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258 		JBrowse link
G Tlr4 toll like receptor 4 involved_in ISO (PMID:20037584)
(PMID:20037584), (PMID:38670073) 		ARUK-UCL
ComplexPortal		 PMID:20037584 PMID:38670073 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tlr6 toll like receptor 6 involved_in ISO (PMID:20037584) ComplexPortal
ARUK-UCL		 PMID:20037584 NCBI chrNW_004955443:8,401,461...8,427,175
Ensembl chrNW_004955443:8,422,534...8,424,942 		JBrowse link
G Tlr9 toll like receptor 9 involved_in ISO (PMID:18820679) UniProt PMID:18820679 NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582 		JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 involved_in ISO (PMID:22011580) UniProt PMID:22011580 NCBI chrNW_004955408:2,575,324...2,621,845
Ensembl chrNW_004955408:2,594,756...2,621,304 		JBrowse link
MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrfip2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chrNW_004955421:3,938,054...4,066,701
Ensembl chrNW_004955421:3,938,054...4,066,060 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 acts_upstream_of_or_within ISO (PMID:12855817)
(PMID:12872135) 		MGI PMID:12855817 PMID:12872135 NCBI chrNW_004955495:4,197,083...4,204,999
Ensembl chrNW_004955495:4,202,372...4,204,513 		JBrowse link
G Tnip3 TNFAIP3 interacting protein 3 involved_in ISO (PMID:17088249) UniProt PMID:17088249 NCBI chrNW_004955428:19,479,633...19,511,738
Ensembl chrNW_004955428:19,479,638...19,511,758 		JBrowse link
negative regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifi16 interferon gamma inducible protein 16 involved_in ISO (PMID:30104205) UniProt PMID:30104205 NCBI chrNW_004955468:10,828,726...10,845,853 JBrowse link
G Trim11 tripartite motif containing 11 involved_in ISO (PMID:27498865) UniProt PMID:27498865 NCBI chrNW_004955581:114,750...123,410
Ensembl chrNW_004955581:114,750...125,143 		JBrowse link
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 molecule involved_in ISO (PMID:24169826)
(PMID:26017478) 		ARUK-UCL PMID:24169826 PMID:26017478 NCBI chrNW_004955468:4,609,601...4,622,601
Ensembl chrNW_004955468:4,612,044...4,625,882 		JBrowse link
G Cd300a CD300a molecule involved_in ISO (PMID:21482706) UniProt PMID:21482706 NCBI chrNW_004955553:1,335,854...1,356,001
Ensembl chrNW_004955553:1,336,227...1,460,376 		JBrowse link
G Cd72 CD72 molecule involved_in ISO (PMID:1711157) UniProt PMID:1711157 NCBI chrNW_004955472:663,451...670,890 JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb involved_in ISO (PMID:24169826) ARUK-UCL PMID:24169826 NCBI chrNW_004955462:14,639,396...14,653,801 JBrowse link
G Fcrl5 Fc receptor like 5 acts_upstream_of_or_within ISO (PMID:23509253) MGI PMID:23509253 NCBI chrNW_004955468:9,434,654...9,464,907
Ensembl chrNW_004955468:9,435,804...9,465,024 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (PMID:28039360) UniProt PMID:28039360 NCBI chrNW_004955467:9,600,829...9,604,148
Ensembl chrNW_004955467:9,600,829...9,603,606 		JBrowse link
G Lpxn leupaxin involved_in ISO (PMID:17640867) UniProt PMID:17640867 NCBI chrNW_004955511:3,459,521...3,500,181
Ensembl chrNW_004955511:3,459,378...3,497,416 		JBrowse link
G Plcl2 phospholipase C like 2 acts_upstream_of_or_within ISO (PMID:14517301) MGI PMID:14517301 NCBI chrNW_004955430:9,157,074...9,347,366
Ensembl chrNW_004955430:9,157,074...9,348,563 		JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 involved_in ISO (PMID:35941532) UniProt PMID:35941532 NCBI chrNW_004955413:4,525,954...4,547,177
Ensembl chrNW_004955413:4,525,954...4,547,177 		JBrowse link
negative regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars2 alanyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:39322678) UniProt PMID:39322678 NCBI chrNW_004955437:9,915,371...9,924,886
Ensembl chrNW_004955437:9,913,867...9,924,886 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:12172553), (PMID:26440888) UniProt PMID:12172553 PMID:26440888 NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904 		JBrowse link
G Aurkb aurora kinase B involved_in ISO (PMID:33542149) UniProt PMID:33542149 NCBI chrNW_004955467:8,715,387...8,720,889
Ensembl chrNW_004955467:8,715,136...8,723,932 		JBrowse link
G Banf1 barrier to autointegration nuclear assembly factor 1 involved_in ISO (PMID:32792394) UniProt PMID:32792394 NCBI chrNW_004955422:19,337,038...19,338,824
Ensembl chrNW_004955422:19,337,038...19,338,824 		JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:32911482), (PMID:32912999) UniProt PMID:32911482 PMID:32912999 NCBI chrNW_004955493:8,593,104...8,607,297 JBrowse link
G Irgm immunity related GTPase M involved_in ISO (PMID:32715615) UniProt PMID:32715615 NCBI chrNW_004955408:2,338,510...2,344,566 JBrowse link
G Lyplal1 lysophospholipase like 1 involved_in ISO (PMID:37802025) UniProt PMID:37802025 NCBI chrNW_004955520:4,251,863...4,281,775
Ensembl chrNW_004955520:4,251,957...4,281,838 		JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:35460603) UniProt PMID:35460603 NCBI chrNW_004955489:520,875...557,609
Ensembl chrNW_004955489:520,875...557,615 		JBrowse link
G Pcbp2 poly(rC) binding protein 2 involved_in ISO (PMID:35322803) UniProt PMID:35322803 NCBI chrNW_004955458:747,770...773,885
Ensembl chrNW_004955458:750,226...773,483 		JBrowse link
G Ppp6c protein phosphatase 6 catalytic subunit involved_in ISO (PMID:32474700) UniProt PMID:32474700 NCBI chrNW_004955419:3,096,882...3,133,590
Ensembl chrNW_004955419:3,096,240...3,134,215 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:33273464) UniProt PMID:33273464 NCBI chrNW_004955454:7,733,697...7,890,896
Ensembl chrNW_004955454:7,733,978...7,890,867 		JBrowse link
G Smpdl3a sphingomyelin phosphodiesterase acid like 3A involved_in ISO (PMID:37890481) UniProt PMID:37890481 NCBI chrNW_004955436:4,655,730...4,663,993
Ensembl chrNW_004955436:4,655,732...4,663,638 		JBrowse link
G Spsb3 splA/ryanodine receptor domain and SOCS box containing 3 involved_in ISO (PMID:38418882) UniProt PMID:38418882 NCBI chrNW_004955442:15,486,845...15,493,422
Ensembl chrNW_004955442:15,487,475...15,493,422 		JBrowse link
G Trex1 three prime repair exonuclease 1 involved_in ISO (PMID:33476576) UniProt PMID:33476576 NCBI chrNW_004955532:533,877...535,767
Ensembl chrNW_004955532:533,877...535,767 		JBrowse link
G Zdhhc18 zDHHC palmitoyltransferase 18 involved_in ISO (PMID:35438208) UniProt PMID:35438208 NCBI chrNW_004955452:6,176,077...6,211,669
Ensembl chrNW_004955452:6,175,991...6,209,902 		JBrowse link
negative regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itch itchy E3 ubiquitin protein ligase involved_in ISO (PMID:27736772) UniProt PMID:27736772 NCBI chrNW_004955422:26,810,829...26,918,517
Ensembl chrNW_004955422:26,809,972...26,887,123 		JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 involved_in ISO (PMID:31881323) UniProt PMID:31881323 NCBI chrNW_004955425:994,787...1,032,426
Ensembl chrNW_004955425:994,163...1,032,426 		JBrowse link
G Rnf39 ring finger protein 39 involved_in ISO (PMID:33674311) UniProt PMID:33674311 NCBI chrNW_004955583:201,638...206,754 JBrowse link
G Sec14l1 SEC14 like lipid binding 1 involved_in ISO (PMID:23843640) UniProt PMID:23843640 NCBI chrNW_004955506:5,159,090...5,231,827
Ensembl chrNW_004955506:5,158,805...5,232,551 		JBrowse link
G Tarbp2 TARBP2 subunit of RISC loading complex involved_in ISO (PMID:30927622) UniProt PMID:30927622 NCBI chrNW_004955458:793,753...798,755
Ensembl chrNW_004955458:793,759...798,806 		JBrowse link
G Tax1bp1 Tax1 binding protein 1 involved_in ISO (PMID:27736772) UniProt PMID:27736772 NCBI chrNW_004955410:29,366,295...29,445,205
Ensembl chrNW_004955410:29,365,844...29,444,302 		JBrowse link
G Tspan6 tetraspanin 6 involved_in ISO (PMID:22908223) UniProt PMID:22908223 NCBI chrNW_004955503:6,782,264...6,788,533
Ensembl chrNW_004955503:6,779,377...6,789,142 		JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:25568335) UniProt PMID:25568335 NCBI chrNW_004955430:6,986,977...7,018,938
Ensembl chrNW_004955430:6,986,759...7,018,938 		JBrowse link
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in ISO (PMID:19164550) UniProt PMID:19164550 NCBI chrNW_004955467:10,788,142...10,792,272
Ensembl chrNW_004955467:10,788,277...10,792,449 		JBrowse link
G Dhx58 DExH-box helicase 58 involved_in ISO (PMID:21187438) UniProt PMID:21187438 NCBI chrNW_004955451:16,186,263...16,191,928
Ensembl chrNW_004955451:16,185,510...16,191,719 		JBrowse link
G Riok3 RIO kinase 3 involved_in ISO (PMID:25865883) UniProt PMID:25865883 NCBI chrNW_004955402:11,649,160...11,670,010
Ensembl chrNW_004955402:11,648,849...11,672,545 		JBrowse link
G Tkfc triokinase and FMN cyclase involved_in ISO (PMID:17600090) UniProt PMID:17600090 NCBI chrNW_004955511:6,200,433...6,235,855
Ensembl chrNW_004955511:6,200,433...6,236,283 		JBrowse link
negative regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a CD300a molecule involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chrNW_004955553:1,335,854...1,356,001
Ensembl chrNW_004955553:1,336,227...1,460,376 		JBrowse link
G Cd300lf CD300 molecule like family member f involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chrNW_004955553:1,596,406...1,610,479
Ensembl chrNW_004955553:1,488,501...1,610,555 		JBrowse link
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd17a abhydrolase domain containing 17A, depalmitoylase involved_in ISO (PMID:38092000) UniProt PMID:38092000 NCBI chrNW_004955495:6,159,314...6,167,429
Ensembl chrNW_004955495:6,159,314...6,168,123 		JBrowse link
G Abhd8 abhydrolase domain containing 8 involved_in ISO (PMID:39225180) UniProt PMID:39225180 NCBI chrNW_004955524:924,128...932,046
Ensembl chrNW_004955524:925,102...930,270 		JBrowse link
G Cptp ceramide-1-phosphate transfer protein involved_in ISO (PMID:29164996) UniProt PMID:29164996 NCBI chrNW_004955486:9,475,520...9,478,925
Ensembl chrNW_004955486:9,475,520...9,478,925 		JBrowse link
G Csnk1a1 casein kinase 1 alpha 1 involved_in ISO (PMID:34615873) UniProt PMID:34615873 NCBI chrNW_004955415:4,921,356...4,966,705
Ensembl chrNW_004955415:4,921,852...4,966,705 		JBrowse link
G Fbxl2 F-box and leucine rich repeat protein 2 involved_in ISO (PMID:26037928) UniProt PMID:26037928 NCBI chrNW_004955421:512,197...617,524
Ensembl chrNW_004955421:512,158...617,524 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in ISO (PMID:36586411) UniProt PMID:36586411 NCBI chrNW_004955412:23,863,513...23,867,984
Ensembl chrNW_004955412:23,862,590...23,867,984 		JBrowse link
G Irgm immunity related GTPase M involved_in ISO (PMID:30612879) UniProt PMID:30612879 NCBI chrNW_004955408:2,338,510...2,344,566 JBrowse link
G Lamp2 lysosomal associated membrane protein 2 involved_in ISO (PMID:36586411) UniProt PMID:36586411 NCBI chrNW_004955572:1,423,048...1,464,443
Ensembl chrNW_004955572:1,422,981...1,462,622 		JBrowse link
G Mefv MEFV innate immunity regulator, pyrin involved_in ISO (PMID:26347139) UniProt PMID:26347139 NCBI chrNW_004955442:14,068,436...14,093,889
Ensembl chrNW_004955442:14,068,348...14,094,016 		JBrowse link
G Nlrc3 NLR family CARD domain containing 3 involved_in ISO (PMID:25277106) UniProt PMID:25277106 NCBI chrNW_004955442:13,795,322...13,834,362
Ensembl chrNW_004955442:13,814,434...13,833,222 		JBrowse link
G Sirt2 sirtuin 2 acts_upstream_of_or_within ISO (PMID:23502856) MGI PMID:23502856 NCBI chrNW_004955468:626,365...644,441
Ensembl chrNW_004955468:626,365...644,441 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within ISO (PMID:32514138)
(PMID:29887864) 		ARUK-UCL PMID:29887864 PMID:32514138 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697 		JBrowse link
G Trim65 tripartite motif containing 65 involved_in ISO (PMID:34512673) UniProt PMID:34512673 NCBI chrNW_004955506:6,362,360...6,366,743
Ensembl chrNW_004955506:6,362,396...6,366,591 		JBrowse link
G Zdhhc12 zDHHC palmitoyltransferase 12 involved_in ISO (PMID:36586411) UniProt PMID:36586411 NCBI chrNW_004955570:1,131,234...1,133,909
Ensembl chrNW_004955570:1,131,234...1,133,909 		JBrowse link
negative regulation of non-canonical inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in ISO (PMID:37962578) UniProt PMID:37962578 NCBI chrNW_004955475:11,062,258...11,112,252
Ensembl chrNW_004955475:11,062,076...11,114,169 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:18342009) BHF-UCL PMID:18342009 NCBI chrNW_004955436:21,566,591...21,581,551
Ensembl chrNW_004955436:21,566,423...21,578,469 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbin erbb2 interacting protein involved_in ISO (PMID:16203728) UniProt PMID:16203728 NCBI chrNW_004955446:3,046,268...3,151,796
Ensembl chrNW_004955446:3,049,258...3,151,796 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23991106) UniProt PMID:23991106 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:18342009) BHF-UCL PMID:18342009 NCBI chrNW_004955436:21,566,591...21,581,551
Ensembl chrNW_004955436:21,566,423...21,578,469 		JBrowse link
G Znrf4 zinc and ring finger 4 involved_in ISO (PMID:28656966) UniProt PMID:28656966 NCBI chrNW_004955495:3,854,178...3,855,556 JBrowse link
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in ISO (PMID:19164550) UniProt PMID:19164550 NCBI chrNW_004955467:10,788,142...10,792,272
Ensembl chrNW_004955467:10,788,277...10,792,449 		JBrowse link
G Dhx58 DExH-box helicase 58 involved_in ISO (PMID:21187438)
(PMID:17475874)
(PMID:18411269) 		UniProt PMID:17475874 PMID:18411269 PMID:21187438 NCBI chrNW_004955451:16,186,263...16,191,928
Ensembl chrNW_004955451:16,185,510...16,191,719 		JBrowse link
G Gpatch3 G-patch domain containing 3 involved_in ISO (PMID:28414768) UniProt PMID:28414768 NCBI chrNW_004955452:6,234,241...6,241,949
Ensembl chrNW_004955452:6,234,241...6,241,991 		JBrowse link
G Nlrx1 NLR family member X1 acts_upstream_of_or_within ISO (PMID:21703540) MGI PMID:21703540 NCBI chrNW_004955412:20,275,767...20,287,414
Ensembl chrNW_004955412:20,275,917...20,287,414 		JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor involved_in ISO (PMID:26471729) UniProt PMID:26471729 NCBI chrNW_004955506:1,451,337...1,513,455
Ensembl chrNW_004955506:1,451,337...1,513,455 		JBrowse link
G Rnf125 ring finger protein 125 involved_in ISO (PMID:17460044), (PMID:26471729) UniProt PMID:17460044 PMID:26471729 NCBI chrNW_004955402:19,276,157...19,310,605
Ensembl chrNW_004955402:19,295,809...19,309,987 		JBrowse link
G Sec14l1 SEC14 like lipid binding 1 involved_in ISO (PMID:23843640) UniProt PMID:23843640 NCBI chrNW_004955506:5,159,090...5,231,827
Ensembl chrNW_004955506:5,158,805...5,232,551 		JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 involved_in ISO (PMID:26471729) UniProt PMID:26471729 NCBI chrNW_004955442:18,548,545...18,568,989
Ensembl chrNW_004955442:18,548,545...18,569,366 		JBrowse link
negative regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btnl2 butyrophilin like 2 acts_upstream_of_or_within ISO (PMID:16751379) MGI PMID:16751379 NCBI chrNW_004955437:1,084,330...1,101,751
Ensembl chrNW_004955437:1,083,745...1,101,730 		JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase involved_in ISO (PMID:38225265) UniProt PMID:38225265 NCBI chrNW_004955485:8,724,375...8,846,647
Ensembl chrNW_004955485:8,724,380...8,837,741 		JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within ISO (PMID:14738763) MGI PMID:14738763 NCBI chrNW_004955427:6,601,651...6,812,896
Ensembl chrNW_004955427:6,604,820...6,812,882 		JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:18193050) UniProt PMID:18193050 NCBI chrNW_004955568:365,700...372,149 JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO (PMID:18424730) UniProt PMID:18424730 NCBI chrNW_004955555:426,894...446,235 JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISO (PMID:12883552) UniProt PMID:12883552 NCBI chrNW_004955422:1,658,237...1,687,000
Ensembl chrNW_004955422:1,657,926...1,695,404 		JBrowse link
G Dusp22 dual specificity phosphatase 22 acts_upstream_of_or_within
involved_in 		ISO (PMID:24714587)
(PMID:38225265) 		MGI
UniProt		 PMID:24714587 PMID:38225265 NCBI chrNW_004955465:12,551,063...12,597,386
Ensembl chrNW_004955465:12,551,063...12,592,572 		JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in ISO (PMID:12447358) UniProt PMID:12447358 NCBI chrNW_004955451:17,064,739...17,069,964 JBrowse link
G Elf1 E74 like ETS transcription factor 1 acts_upstream_of_or_within ISO (PMID:14738763) MGI PMID:14738763 NCBI chrNW_004955404:50,952,907...51,020,229
Ensembl chrNW_004955404:50,952,907...51,020,229 		JBrowse link
G Ezr ezrin involved_in ISO (PMID:20551903) UniProt PMID:20551903 NCBI chrNW_004955439:3,701,722...3,740,345
Ensembl chrNW_004955439:3,703,013...3,740,345 		JBrowse link
G Itpripl1 ITPRIP like 1 involved_in ISO (PMID:38614099) UniProt PMID:38614099 NCBI chrNW_004955470:3,870,296...3,873,212
Ensembl chrNW_004955470:3,870,296...3,873,212 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:18619870) ARUK-UCL PMID:18619870 NCBI chrNW_004955452:9,335,481...9,358,177
Ensembl chrNW_004955452:9,334,587...9,358,444 		JBrowse link
G Lgals3 galectin 3 involved_in ISO (PMID:19706535) BHF-UCL PMID:19706535 NCBI chrNW_004955409:8,448,120...8,452,437
Ensembl chrNW_004955409:8,447,774...8,452,438 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO (PMID:38614099) UniProt PMID:38614099 NCBI chrNW_004955501:1,867,956...1,963,091 JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO (PMID:12970181) MGI PMID:12970181 NCBI chrNW_004955405:18,434,711...18,540,710
Ensembl chrNW_004955405:18,434,711...18,540,710 		JBrowse link
G Phpt1 phosphohistidine phosphatase 1 involved_in ISO (PMID:18796614) BHF-UCL PMID:18796614 NCBI chrNW_004955513:4,930,951...4,932,509
Ensembl chrNW_004955513:4,930,951...4,932,509 		JBrowse link
G Prnp prion protein (Kanno blood group) involved_in ISO (PMID:20145049) BHF-UCL PMID:20145049 NCBI chrNW_004955415:15,442,313...15,454,644
Ensembl chrNW_004955415:15,442,313...15,454,644 		JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (PMID:22080863) UniProt PMID:22080863 NCBI chrNW_004955402:771,410...846,671 JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:18056643) UniProt PMID:18056643 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within ISO (PMID:9064344) MGI PMID:9064344 NCBI chrNW_004955413:4,525,954...4,547,177
Ensembl chrNW_004955413:4,525,954...4,547,177 		JBrowse link
G Ptprj protein tyrosine phosphatase receptor type J involved_in ISO (PMID:12913111)
(PMID:11259588), (PMID:9780142) 		UniProt PMID:9780142 PMID:11259588 PMID:12913111 NCBI chrNW_004955422:396,266...438,792
Ensembl chrNW_004955422:399,357...443,054 		JBrowse link
G Pvrig PVR related immunoglobulin domain containing involved_in ISO (PMID:26755705) UniProt PMID:26755705 NCBI chrNW_004955573:592,438...595,056 JBrowse link
G Sh2d1a SH2 domain containing 1A involved_in ISO (PMID:9774102) UniProt PMID:9774102 NCBI chrNW_004955473:10,345,407...10,370,535
Ensembl chrNW_004955473:10,346,943...10,370,575 		JBrowse link
G Sla2 Src like adaptor 2 involved_in ISO (PMID:11891219) UniProt PMID:11891219 NCBI chrNW_004955422:24,978,447...25,003,732
Ensembl chrNW_004955422:24,986,028...25,003,732 		JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in ISO (PMID:9285719) UniProt PMID:9285719 NCBI chrNW_004955412:20,480,284...20,484,958
Ensembl chrNW_004955412:20,480,284...20,484,958 		JBrowse link
G Ubash3a ubiquitin associated and SH3 domain containing A acts_upstream_of_or_within ISO (PMID:14738763) MGI PMID:14738763 NCBI chrNW_004955407:39,290,025...39,325,810
Ensembl chrNW_004955407:39,290,827...39,326,004 		JBrowse link
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450) UniProt PMID:23609450 NCBI chrNW_004955404:30,254,934...30,266,898
Ensembl chrNW_004955404:30,254,841...30,270,921 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:20385881) UniProt PMID:20385881 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:26599367) UniProt PMID:26599367 NCBI chrNW_004955463:4,900,115...4,993,793
Ensembl chrNW_004955463:4,900,060...4,993,793 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15220916) MGI PMID:15220916 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G Tlr6 toll like receptor 6 involved_in ISO (PMID:22198949) ARUK-UCL PMID:22198949 NCBI chrNW_004955443:8,401,461...8,427,175
Ensembl chrNW_004955443:8,422,534...8,424,942 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514) ARUK-UCL PMID:31134514 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697 		JBrowse link
negative regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19865078) UniProt PMID:19865078 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:15474016) BHF-UCL PMID:15474016 NCBI chrNW_004955436:21,566,591...21,581,551
Ensembl chrNW_004955436:21,566,423...21,578,469 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in ISO (PMID:21695056) CACAO PMID:21695056 NCBI chrNW_004955432:3,575,034...3,617,029
Ensembl chrNW_004955432:3,575,272...3,616,691 		JBrowse link
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450) UniProt PMID:23609450 NCBI chrNW_004955404:30,254,934...30,266,898
Ensembl chrNW_004955404:30,254,841...30,270,921 		JBrowse link
G Bpifb1 BPI fold containing family B member 1 involved_in ISO (PMID:21900486) UniProt PMID:21900486 NCBI chrNW_004955422:27,955,298...27,976,051
Ensembl chrNW_004955422:27,950,918...27,975,146 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO (PMID:19948740) UniProt PMID:19948740 NCBI chrNW_004955419:6,229,437...6,416,619
Ensembl chrNW_004955419:6,228,591...6,416,402 		JBrowse link
G LOC102006100 TIR domain-containing adapter molecule 2 involved_in ISO (PMID:19412184) UniProt PMID:19412184 NCBI chrNW_004955408:35,342,733...35,382,821
Ensembl chrNW_004955408:35,374,508...35,382,314 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:20385881) UniProt PMID:20385881 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:28609714) UniProt PMID:28609714 NCBI chrNW_004955463:4,900,115...4,993,793
Ensembl chrNW_004955463:4,900,060...4,993,793 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1 group D member 1 involved_in ISO (PMID:18511497) BHF-UCL PMID:18511497 NCBI chrNW_004955451:14,743,763...14,750,903
Ensembl chrNW_004955451:14,742,735...14,750,999 		JBrowse link
G Rab7b RAB7B, member RAS oncogene family involved_in ISO (PMID:17395780) UniProt PMID:17395780 NCBI chrNW_004955406:41,615,302...41,638,157
Ensembl chrNW_004955406:41,615,302...41,638,151 		JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO (PMID:31281713) UniProt PMID:31281713 NCBI chrNW_004955408:757,426...764,989
Ensembl chrNW_004955408:757,426...771,615 		JBrowse link
G Tax1bp1 Tax1 binding protein 1 involved_in ISO (PMID:28898289) UniProt PMID:28898289 NCBI chrNW_004955410:29,366,295...29,445,205
Ensembl chrNW_004955410:29,365,844...29,444,302 		JBrowse link
G Ticam2 toll like receptor adaptor molecule 2 involved_in ISO (PMID:19412184) UniProt PMID:19412184 NCBI chrNW_004955411:31,010,373...31,042,321 JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514)
(PMID:29407460) 		ARUK-UCL PMID:29407460 PMID:31134514 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697 		JBrowse link
G Trim32 tripartite motif containing 32 involved_in ISO (PMID:28898289) UniProt PMID:28898289 NCBI chrNW_004955419:11,151,751...11,168,046
Ensembl chrNW_004955419:11,151,751...11,168,041 		JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:19912257) BHF-UCL PMID:19912257 NCBI chrNW_004955436:21,566,591...21,581,551
Ensembl chrNW_004955436:21,566,423...21,578,469 		JBrowse link
negative regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gramd4 GRAM domain containing 4 involved_in ISO (PMID:25917084) UniProt PMID:25917084 NCBI chrNW_004955413:30,603,820...30,656,940
Ensembl chrNW_004955413:30,603,580...30,656,940 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO (PMID:14716310) UniProt PMID:14716310 NCBI chrNW_004955452:17,518,345...17,549,112
Ensembl chrNW_004955452:17,529,115...17,549,664 		JBrowse link
G Ptprs protein tyrosine phosphatase receptor type S involved_in ISO (PMID:26231120) UniProt PMID:26231120 NCBI chrNW_004955495:3,943,075...3,991,361
Ensembl chrNW_004955495:3,943,170...3,990,927 		JBrowse link
G Rab7b RAB7B, member RAS oncogene family involved_in ISO (PMID:19587007) UniProt PMID:19587007 NCBI chrNW_004955406:41,615,302...41,638,157
Ensembl chrNW_004955406:41,615,302...41,638,151 		JBrowse link
negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin beta 2 involved_in ISO (PMID:16378096) UniProt PMID:16378096 NCBI chrNW_004955467:10,109,985...10,118,687
Ensembl chrNW_004955467:10,110,003...10,123,022 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) UniProt PMID:20829348 NCBI chrNW_004955495:5,561,359...5,571,945
Ensembl chrNW_004955495:5,561,979...5,571,682 		JBrowse link
G Gpr108 G protein-coupled receptor 108 involved_in ISO (PMID:30332431) UniProt PMID:30332431 NCBI chrNW_004955495:2,782,549...2,789,470
Ensembl chrNW_004955495:2,782,606...2,789,815 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (PMID:28039360) UniProt PMID:28039360 NCBI chrNW_004955467:9,600,829...9,604,148
Ensembl chrNW_004955467:9,600,829...9,603,606 		JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 involved_in ISO (PMID:12150927) BHF-UCL PMID:12150927 NCBI chrNW_004955458:12,839,995...12,880,285
Ensembl chrNW_004955458:12,846,237...12,879,316 		JBrowse link
G Irf4 interferon regulatory factor 4 acts_upstream_of_or_within ISO (PMID:16236719) MGI PMID:16236719 NCBI chrNW_004955465:12,497,534...12,512,529
Ensembl chrNW_004955465:12,497,462...12,513,106 		JBrowse link
G Lgr4 leucine rich repeat containing G protein-coupled receptor 4 involved_in ISO (PMID:23589304) UniProt PMID:23589304 NCBI chrNW_004955476:6,611,102...6,629,294
Ensembl chrNW_004955476:6,610,103...6,629,264 		JBrowse link
G Lrrc14 leucine rich repeat containing 14 involved_in ISO (PMID:27426725) UniProt PMID:27426725 NCBI chrNW_004955454:3,142,621...3,146,470
Ensembl chrNW_004955454:3,142,636...3,146,470 		JBrowse link
G Nfkbil1 NFKB inhibitor like 1 involved_in ISO (PMID:20829348) UniProt PMID:20829348 NCBI chrNW_004955437:90,623...100,918
Ensembl chrNW_004955437:90,577...100,918 		JBrowse link
G Nlrp6 NLR family pyrin domain containing 6 acts_upstream_of_or_within ISO (PMID:22763455) MGI PMID:22763455 NCBI chrNW_004955476:11,755,489...11,762,781 JBrowse link
G Otud4 OTU deubiquitinase 4 involved_in ISO (PMID:29395066) UniProt PMID:29395066 NCBI chrNW_004955428:1,062,998...1,108,711
Ensembl chrNW_004955428:1,062,998...1,115,415 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (PMID:20584979) UniProt PMID:20584979 NCBI chrNW_004955442:14,685,089...14,772,870
Ensembl chrNW_004955442:14,685,153...14,772,870 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) UniProt PMID:20728433 NCBI chrNW_004955507:2,805,782...2,918,664
Ensembl chrNW_004955507:2,801,970...2,918,670 		JBrowse link
G Rnf115 ring finger protein 115 involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chrNW_004955568:263,302...349,192
Ensembl chrNW_004955568:263,302...349,192 		JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase acid like 3B involved_in ISO (PMID:26095358) UniProt PMID:26095358 NCBI chrNW_004955452:7,114,746...7,138,924
Ensembl chrNW_004955452:7,115,204...7,139,370 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in ISO (PMID:18083102) UniProt PMID:18083102 NCBI chrNW_004955416:8,361,722...8,377,629
Ensembl chrNW_004955416:8,359,207...8,377,692 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chrNW_004955481:1,752,778...1,805,700
Ensembl chrNW_004955481:1,752,778...1,808,583 		JBrowse link
NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 acts_upstream_of ISO (PMID:23502856) MGI PMID:23502856 NCBI chrNW_004955583:643,575...652,393 JBrowse link
G Gkn2 gastrokine 2 acts_upstream_of_or_within ISO (PMID:32226647) MGI PMID:32226647 NCBI chrNW_004955424:16,071,246...16,078,008
Ensembl chrNW_004955424:16,071,246...16,078,008 		JBrowse link
G Kcnj8 potassium inwardly rectifying channel subfamily J member 8 acts_upstream_of_or_within ISO (PMID:28928055) MGI PMID:28928055 NCBI chrNW_004955413:17,364,447...17,371,255
Ensembl chrNW_004955413:17,364,213...17,371,255 		JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 acts_upstream_of_or_within
involved_in 		ISO (PMID:22753929)
(PMID:17483456), (PMID:23582325), (PMID:25686105), (PMID:27043286), (PMID:27432880), (PMID:28465465), (PMID:28656979), (PMID:28943315), (PMID:30487600), (PMID:31189953), (PMID:33231615), (PMID:34554188), (PMID:34615873), (PMID:35114687), (PMID:35254907), (PMID:35559676), (PMID:36442502), (PMID:39173637)
(PMID:23582325), (PMID:26173909), (PMID:27043286), (PMID:28465465), (PMID:28656979), (PMID:28716882), (PMID:28943315), (PMID:30487600), (PMID:34615873), (PMID:34861190) 		MGI
UniProt		 PMID:17483456 PMID:22753929 PMID:23582325 PMID:25686105 PMID:26173909 More... NCBI chrNW_004955581:597,952...616,903
Ensembl chrNW_004955581:597,667...617,410 		JBrowse link
G Sirt2 sirtuin 2 acts_upstream_of ISO (PMID:23502856) MGI PMID:23502856 NCBI chrNW_004955468:626,365...644,441
Ensembl chrNW_004955468:626,365...644,441 		JBrowse link
NLRP6 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlrp6 NLR family pyrin domain containing 6 involved_in ISO (PMID:30674671), (PMID:31932628), (PMID:34678144)
(PMID:32424362), (PMID:34678144) 		UniProt PMID:30674671 PMID:31932628 PMID:32424362 PMID:34678144 NCBI chrNW_004955476:11,755,489...11,762,781 JBrowse link
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf34 ring finger protein 34 involved_in ISO (PMID:25012219) UniProt PMID:25012219 NCBI chrNW_004955482:6,889,112...6,905,139
Ensembl chrNW_004955482:6,891,546...6,905,139 		JBrowse link
nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkbia NFKB inhibitor alpha acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004955409:25,691,673...25,695,151
Ensembl chrNW_004955409:25,691,534...25,697,520 		JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 involved_in ISO (PMID:11058605), (PMID:12791997), (PMID:12796777)
(PMID:27007849) 		UniProt PMID:11058605 PMID:12791997 PMID:12796777 PMID:27007849 NCBI chrNW_004955410:31,681,191...31,725,173
Ensembl chrNW_004955410:31,681,077...31,725,173 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within 		ISO (PMID:29452636), (PMID:30279485)
(PMID:11894098) 		UniProt
MGI		 PMID:11894098 PMID:29452636 PMID:30279485 NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228 		JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in ISO (PMID:29452636) UniProt PMID:29452636 NCBI chrNW_004955473:10,823,795...10,878,256
Ensembl chrNW_004955473:10,827,435...10,840,604 		JBrowse link
nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inava innate immunity activator involved_in ISO (PMID:28436939) UniProt PMID:28436939 NCBI chrNW_004955406:37,086,302...37,107,221
Ensembl chrNW_004955406:37,086,302...37,107,221 		JBrowse link
G Irgm immunity related GTPase M involved_in ISO (PMID:25891078) UniProt PMID:25891078 NCBI chrNW_004955408:2,338,510...2,344,566 JBrowse link
G Lacc1 laccase domain containing 1 involved_in ISO (PMID:31875558) UniProt PMID:31875558 NCBI chrNW_004955518:1,794,067...1,809,150
Ensembl chrNW_004955518:1,793,352...1,805,808 		JBrowse link
G Nfkbia NFKB inhibitor alpha acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004955409:25,691,673...25,695,151
Ensembl chrNW_004955409:25,691,534...25,697,520 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in 		ISO (PMID:12527755)
(PMID:15692052)
(PMID:27007849)
(PMID:23892723)
(PMID:12626759), (PMID:15044951), (PMID:17355968), (PMID:23806334), (PMID:31649195) 		MGI
UniProt		 PMID:12527755 PMID:12626759 PMID:15044951 PMID:15692052 PMID:17355968 More... NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G Otulin OTU deubiquitinase with linear linkage specificity involved_in ISO (PMID:23806334) UniProt PMID:23806334 NCBI chrNW_004955426:3,953,852...3,982,532
Ensembl chrNW_004955426:3,953,933...3,982,175 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit acts_upstream_of_or_within ISO (PMID:12527755) MGI PMID:12527755 NCBI chrNW_004955422:19,602,930...19,612,263
Ensembl chrNW_004955422:19,603,345...19,611,516 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within 		ISO (PMID:16824733), (PMID:17355968), (PMID:17562858), (PMID:23806334), (PMID:28545134), (PMID:29452636), (PMID:30026309), (PMID:30279485), (PMID:30478312)
(PMID:17947236)
(PMID:11894098) 		UniProt
MGI		 PMID:11894098 PMID:16824733 PMID:17355968 PMID:17562858 PMID:17947236 More... NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228 		JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in ISO (PMID:19667203), (PMID:22607974), (PMID:29452636) UniProt PMID:19667203 PMID:22607974 PMID:29452636 NCBI chrNW_004955473:10,823,795...10,878,256
Ensembl chrNW_004955473:10,827,435...10,840,604 		JBrowse link
pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:23258413) UniProt PMID:23258413 NCBI chrNW_004955493:8,593,104...8,607,297 JBrowse link
G Clec4e C-type lectin domain family 4 member E involved_in ISO (PMID:24101491) UniProt PMID:24101491 NCBI chrNW_004955413:5,256,523...5,261,385
Ensembl chrNW_004955413:5,256,440...5,262,938 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) UniProt PMID:28436939 NCBI chrNW_004955406:37,086,302...37,107,221
Ensembl chrNW_004955406:37,086,302...37,107,221 		JBrowse link
G Lacc1 laccase domain containing 1 involved_in ISO (PMID:28593945), (PMID:31875558) UniProt PMID:28593945 PMID:31875558 NCBI chrNW_004955518:1,794,067...1,809,150
Ensembl chrNW_004955518:1,793,352...1,805,808 		JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 involved_in ISO (PMID:31649195) UniProt PMID:31649195 NCBI chrNW_004955410:31,681,191...31,725,173
Ensembl chrNW_004955410:31,681,077...31,725,173 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 involved_in ISO (PMID:31649195) UniProt PMID:31649195 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G Rnf144a ring finger protein 144A involved_in ISO (PMID:37955227) UniProt PMID:37955227 NCBI chrNW_004955487:1,884,179...1,985,559
Ensembl chrNW_004955487:1,883,835...1,966,469 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (PMID:23910378) UniProt PMID:23910378 NCBI chrNW_004955418:1,091,022...1,097,064
Ensembl chrNW_004955418:1,083,613...1,100,448 		JBrowse link
positive regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:25774715), (PMID:25774716) UniProt PMID:25774715 PMID:25774716 NCBI chrNW_004955423:4,914,430...4,926,850
Ensembl chrNW_004955423:4,917,590...4,926,007 		JBrowse link
positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO (PMID:8692271) UniProt PMID:8692271 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 CD81 molecule involved_in ISO (PMID:20237408)
(PMID:23499492) 		UniProt PMID:20237408 PMID:23499492 NCBI chrNW_004955422:14,155,682...14,175,181
Ensembl chrNW_004955422:14,155,682...14,175,181 		JBrowse link
G Cmtm3 CKLF like MARVEL transmembrane domain containing 3 acts_upstream_of_or_within ISO (PMID:15196959) MGI PMID:15196959 NCBI chrNW_004955433:23,178,062...23,185,666
Ensembl chrNW_004955433:23,178,061...23,185,666 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:30111844) ARUK-UCL PMID:30111844 NCBI chrNW_004955421:16,595,445...17,075,923
Ensembl chrNW_004955421:16,595,471...17,075,923 		JBrowse link
G Prkch protein kinase C eta involved_in ISO (PMID:18780722) UniProt PMID:18780722 NCBI chrNW_004955466:8,178,323...8,393,446
Ensembl chrNW_004955466:8,176,876...8,393,446 		JBrowse link
G Slc39a10 solute carrier family 39 member 10 acts_upstream_of_or_within ISO (PMID:25074919) MGI PMID:25074919 NCBI chrNW_004955403:4,426,538...4,479,693 JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (PMID:10518561) BHF-UCL PMID:10518561 NCBI chrNW_004955447:5,292,708...5,345,214
Ensembl chrNW_004955447:5,293,227...5,330,187 		JBrowse link
positive regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase involved_in ISO (PMID:25704810) UniProt PMID:25704810 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:37832545) UniProt PMID:37832545 NCBI chrNW_004955411:17,177,335...17,229,957
Ensembl chrNW_004955411:17,177,335...17,229,957 		JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 involved_in ISO (PMID:37916870) UniProt PMID:37916870 NCBI chrNW_004955425:994,787...1,032,426
Ensembl chrNW_004955425:994,163...1,032,426 		JBrowse link
G Rnf39 ring finger protein 39 involved_in ISO (PMID:39255680) UniProt PMID:39255680 NCBI chrNW_004955583:201,638...206,754 JBrowse link
G Slc19a1 solute carrier family 19 member 1 involved_in ISO (PMID:36745868) UniProt PMID:36745868 NCBI chrNW_004955407:42,132,216...42,154,252
Ensembl chrNW_004955407:42,132,165...42,141,992 		JBrowse link
G Tab1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 involved_in ISO (PMID:37832545) UniProt PMID:37832545 NCBI chrNW_004955413:25,290,733...25,315,267
Ensembl chrNW_004955413:25,290,828...25,313,969 		JBrowse link
G Zdhhc9 zDHHC palmitoyltransferase 9 involved_in ISO (PMID:37802025) UniProt PMID:37802025 NCBI chrNW_004955473:5,174,575...5,208,767
Ensembl chrNW_004955473:5,174,563...5,208,767 		JBrowse link
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in ISO (PMID:16831868) BHF-UCL PMID:16831868 NCBI chrNW_004955402:53,408,861...53,560,896
Ensembl chrNW_004955402:53,473,131...53,560,924 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:16177098 RGD:1578516 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO (PMID:18249142) ARUK-UCL PMID:18249142 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Ptprj protein tyrosine phosphatase receptor type J involved_in ISO (PMID:18249142) ARUK-UCL PMID:18249142 NCBI chrNW_004955422:396,266...438,792
Ensembl chrNW_004955422:399,357...443,054 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family ISO RGD PMID:18832707 RGD:9835043 NCBI chrNW_004955435:15,090,521...15,171,397
Ensembl chrNW_004955435:15,150,827...15,171,397 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 ISO RGD PMID:18832707 RGD:9835043 NCBI chrNW_004955513:1,224,418...1,328,176
Ensembl chrNW_004955513:1,226,205...1,315,922 		JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (PMID:25568335) UniProt PMID:25568335 NCBI chrNW_004955405:39,503,020...39,540,069
Ensembl chrNW_004955405:39,503,020...39,540,335 		JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr4a3 nuclear receptor subfamily 4 group A member 3 involved_in ISO (PMID:24586680) UniProt PMID:24586680 NCBI chrNW_004955419:25,779,368...25,817,445
Ensembl chrNW_004955419:25,779,178...25,818,706 		JBrowse link
positive regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd17 ankyrin repeat domain 17 involved_in ISO (PMID:22328336) UniProt PMID:22328336 NCBI chrNW_004955447:259,654...376,147
Ensembl chrNW_004955447:259,655...376,147 		JBrowse link
G Ddx60 DExD/H-box helicase 60 involved_in ISO (PMID:21791617) UniProt PMID:21791617 NCBI chrNW_004955403:37,679,939...37,765,074
Ensembl chrNW_004955403:37,679,730...37,765,886 		JBrowse link
G Dhx58 DExH-box helicase 58 involved_in ISO (PMID:20080593) UniProt PMID:20080593 NCBI chrNW_004955451:16,186,263...16,191,928
Ensembl chrNW_004955451:16,185,510...16,191,719 		JBrowse link
positive regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc134 coiled-coil domain containing 134 involved_in ISO (PMID:38670073) UniProt PMID:38670073 NCBI chrNW_004955413:27,248,879...27,265,635
Ensembl chrNW_004955413:27,249,272...27,265,635 		JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 acts_upstream_of_or_within ISO (PMID:23502856) MGI PMID:23502856 NCBI chrNW_004955583:643,575...652,393 JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISO (PMID:28943315)
(PMID:23246432) 		UniProt PMID:23246432 PMID:28943315 NCBI chrNW_004955594:551,407...613,772
Ensembl chrNW_004955594:554,081...613,661 		JBrowse link
G Btk Bruton tyrosine kinase involved_in ISO (PMID:34554188) UniProt PMID:34554188 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120 		JBrowse link
G Cd36 CD36 molecule (CD36 blood group) involved_in ISO (PMID:23812099) UniProt PMID:23812099 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313 		JBrowse link
G Ddx3x DEAD-box helicase 3 X-linked involved_in ISO (PMID:31511697) UniProt PMID:31511697 NCBI chrNW_004955565:1,387,043...1,403,624
Ensembl chrNW_004955565:1,386,973...1,404,220 		JBrowse link
G Dhx33 DEAH-box helicase 33 involved_in ISO (PMID:23871209) UniProt PMID:23871209 NCBI chrNW_004955467:10,797,464...10,819,083
Ensembl chrNW_004955467:10,793,934...10,818,898 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:22461501) UniProt PMID:22461501 NCBI chrNW_004955423:4,914,430...4,926,850
Ensembl chrNW_004955423:4,917,590...4,926,007 		JBrowse link
G Lats1 large tumor suppressor kinase 1 involved_in ISO (PMID:39173637) UniProt PMID:39173637 NCBI chrNW_004955439:11,559,655...11,611,287
Ensembl chrNW_004955439:11,559,657...11,611,660 		JBrowse link
G Lats2 large tumor suppressor kinase 2 involved_in ISO (PMID:39173637) UniProt PMID:39173637 NCBI chrNW_004955497:1,711,882...1,768,177
Ensembl chrNW_004955497:1,711,205...1,761,584 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISO (PMID:28943315) UniProt PMID:28943315 NCBI chrNW_004955556:1,593,552...1,705,543
Ensembl chrNW_004955556:1,593,494...1,665,784 		JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 involved_in ISO (PMID:37575012) UniProt PMID:37575012 NCBI chrNW_004955425:994,787...1,032,426
Ensembl chrNW_004955425:994,163...1,032,426 		JBrowse link
G Mark4 microtubule affinity regulating kinase 4 involved_in ISO (PMID:28656979) UniProt PMID:28656979 NCBI chrNW_004955555:2,284,615...2,315,152
Ensembl chrNW_004955555:2,286,365...2,315,146 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:23582325) UniProt PMID:23582325 NCBI chrNW_004955415:14,691,918...14,704,782
Ensembl chrNW_004955415:14,695,438...14,703,672 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor involved_in ISO (PMID:33718825) UniProt PMID:33718825 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Nek7 NIMA related kinase 7 involved_in ISO (PMID:26642356)
(PMID:31189953), (PMID:36442502), (PMID:39173637)
(PMID:26814970) 		UniProt PMID:26642356 PMID:26814970 PMID:31189953 PMID:36442502 PMID:39173637 NCBI chrNW_004955406:34,575,292...34,714,024
Ensembl chrNW_004955406:34,626,494...34,717,546 		JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in ISO (PMID:29958799) UniProt PMID:29958799 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926 		JBrowse link
G Plcg2 phospholipase C gamma 2 acts_upstream_of_or_within ISO (PMID:32514138) ARUK-UCL PMID:32514138 NCBI chrNW_004955522:4,352,890...4,480,735
Ensembl chrNW_004955522:4,358,233...4,468,986 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISO (PMID:28465465) UniProt PMID:28465465 NCBI chrNW_004955408:5,435,117...5,460,361
Ensembl chrNW_004955408:5,433,268...5,460,361 		JBrowse link
G Prkd1 protein kinase D1 involved_in ISO (PMID:28716882) UniProt PMID:28716882 NCBI chrNW_004955409:30,554,095...30,860,588
Ensembl chrNW_004955409:30,554,013...30,860,649 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:27043286) UniProt PMID:27043286 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Stmp1 short transmembrane mitochondrial protein 1 involved_in ISO (PMID:31836654) UniProt PMID:31836654 NCBI chrNW_004955494:7,063,374...7,077,052 JBrowse link
G Tlr4 toll like receptor 4 involved_in ISO (PMID:23812099) UniProt PMID:23812099 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tlr6 toll like receptor 6 involved_in ISO (PMID:23812099) UniProt PMID:23812099 NCBI chrNW_004955443:8,401,461...8,427,175
Ensembl chrNW_004955443:8,422,534...8,424,942 		JBrowse link
G Usp50 ubiquitin specific peptidase 50 acts_upstream_of_or_within ISO (PMID:28094437) MGI PMID:28094437 NCBI chrNW_004955409:3,788,723...3,838,077
Ensembl chrNW_004955409:3,788,903...3,837,983 		JBrowse link
G Zdhhc1 zDHHC palmitoyltransferase 1 involved_in ISO (PMID:39173637) UniProt PMID:39173637 NCBI chrNW_004955484:9,224,559...9,245,894
Ensembl chrNW_004955484:9,234,319...9,245,894 		JBrowse link
G Zdhhc5 zDHHC palmitoyltransferase 5 involved_in ISO (PMID:38092000) UniProt PMID:38092000 NCBI chrNW_004955511:2,597,353...2,625,139
Ensembl chrNW_004955511:2,601,803...2,624,151 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:19570976), (PMID:21277849) UniProt PMID:19570976 PMID:21277849 NCBI chrNW_004955482:2,327,137...2,343,980 JBrowse link
G Slc46a2 solute carrier family 46 member 2 involved_in ISO (PMID:28539433) FlyBase PMID:28539433 NCBI chrNW_004955419:14,547,393...14,557,447
Ensembl chrNW_004955419:14,547,103...14,557,531 		JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nagk N-acetylglucosamine kinase involved_in ISO (PMID:36002575) UniProt PMID:36002575 NCBI chrNW_004955424:14,205,689...14,215,201
Ensembl chrNW_004955424:14,205,813...14,215,156 		JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chrNW_004955422:18,868,696...18,877,826
Ensembl chrNW_004955422:18,868,696...18,877,438 		JBrowse link
G Slc15a3 solute carrier family 15 member 3 involved_in ISO (PMID:24695226) UniProt PMID:24695226 NCBI chrNW_004955511:5,574,686...5,582,992
Ensembl chrNW_004955511:5,574,840...5,582,307 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:24695226) UniProt PMID:24695226 NCBI chrNW_004955482:2,327,137...2,343,980 JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
positive regulation of pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zdhhc5 zDHHC palmitoyltransferase 5 involved_in ISO (PMID:31649195) UniProt PMID:31649195 NCBI chrNW_004955511:2,597,353...2,625,139
Ensembl chrNW_004955511:2,601,803...2,624,151 		JBrowse link
positive regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd17 ankyrin repeat domain 17 involved_in ISO (PMID:22328336) UniProt PMID:22328336 NCBI chrNW_004955447:259,654...376,147
Ensembl chrNW_004955447:259,655...376,147 		JBrowse link
G Ddx60 DExD/H-box helicase 60 involved_in ISO (PMID:21791617) UniProt PMID:21791617 NCBI chrNW_004955403:37,679,939...37,765,074
Ensembl chrNW_004955403:37,679,730...37,765,886 		JBrowse link
G Dhx58 DExH-box helicase 58 involved_in ISO (PMID:20080593) UniProt PMID:20080593 NCBI chrNW_004955451:16,186,263...16,191,928
Ensembl chrNW_004955451:16,185,510...16,191,719 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase like involved_in ISO (PMID:25925578) ARUK-UCL PMID:25925578 NCBI chrNW_004955455:10,658,080...10,682,493
Ensembl chrNW_004955455:10,657,440...10,682,546 		JBrowse link
G Pum1 pumilio RNA binding family member 1 involved_in ISO (PMID:25340845) UniProt PMID:25340845 NCBI chrNW_004955452:9,487,725...9,623,565
Ensembl chrNW_004955452:9,487,725...9,624,066 		JBrowse link
G Pum2 pumilio RNA binding family member 2 involved_in ISO (PMID:25340845) UniProt PMID:25340845 NCBI chrNW_004955469:2,810,825...2,886,911
Ensembl chrNW_004955469:2,810,573...2,886,611 		JBrowse link
G Trim15 tripartite motif containing 15 involved_in ISO (PMID:23077300) UniProt PMID:23077300 NCBI chrNW_004955583:277,564...283,422 JBrowse link
G Usp15 ubiquitin specific peptidase 15 involved_in ISO (PMID:24399297) CACAO PMID:24399297 NCBI chrNW_004955458:9,440,645...9,533,653
Ensembl chrNW_004955458:9,403,097...9,533,653 		JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 involved_in ISO (PMID:21102435) UniProt PMID:21102435 NCBI chrNW_004955494:3,925,478...3,985,469
Ensembl chrNW_004955494:3,926,413...3,983,736 		JBrowse link
G Zcchc3 zinc finger CCHC-type containing 3 involved_in ISO (PMID:30193849) UniProt PMID:30193849 NCBI chrNW_004955597:194,912...197,697
Ensembl chrNW_004955597:195,002...196,231 		JBrowse link
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (PMID:11435465) MGI PMID:11435465 NCBI chrNW_004955445:12,696,096...12,717,488
Ensembl chrNW_004955445:12,696,096...12,717,488 		JBrowse link
G Bcl10 BCL10 immune signaling adaptor involved_in ISO (PMID:18287044), (PMID:27777308) UniProt PMID:18287044 PMID:27777308 NCBI chrNW_004955423:8,710,231...8,720,530
Ensembl chrNW_004955423:8,709,890...8,722,050 		JBrowse link
G Card11 caspase recruitment domain family member 11 involved_in ISO (PMID:12154360)
(PMID:12154356) 		UniProt PMID:12154356 PMID:12154360 NCBI chrNW_004955460:12,368,987...12,487,675
Ensembl chrNW_004955460:12,368,918...12,490,041 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (PMID:17785582) BHF-UCL PMID:17785582 NCBI chrNW_004955451:15,086,119...15,101,862
Ensembl chrNW_004955451:15,086,119...15,095,561 		JBrowse link
G Cd226 CD226 molecule involved_in ISO (PMID:26755705) UniProt PMID:26755705 NCBI chrNW_004955402:53,408,861...53,560,896
Ensembl chrNW_004955402:53,473,131...53,560,924 		JBrowse link
G Cd81 CD81 molecule involved_in ISO (PMID:23858057) UniProt PMID:23858057 NCBI chrNW_004955422:14,155,682...14,175,181
Ensembl chrNW_004955422:14,155,682...14,175,181 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase acts_upstream_of_or_within ISO (PMID:16501569) MGI PMID:16501569 NCBI chrNW_004955433:8,788,867...8,845,925
Ensembl chrNW_004955433:8,788,655...8,845,925 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (PMID:18287044), (PMID:27777308) UniProt PMID:18287044 PMID:27777308 NCBI chrNW_004955580:1,053,823...1,069,802
Ensembl chrNW_004955580:1,053,823...1,069,802 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 involved_in ISO (PMID:18796614) BHF-UCL PMID:18796614 NCBI chrNW_004955555:1,493,600...1,509,113
Ensembl chrNW_004955555:1,490,052...1,509,113 		JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within ISO (PMID:19179613) MGI PMID:19179613 NCBI chrNW_004955425:3,718,291...3,755,942
Ensembl chrNW_004955425:3,718,206...3,756,142 		JBrowse link
G LOC102018114 T-cell receptor-associated transmembrane adapter 1 acts_upstream_of_or_within ISO (PMID:11390434) MGI PMID:11390434 NCBI chrNW_004955427:9,665,479...9,700,305
Ensembl chrNW_004955427:9,665,456...9,699,788 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO (PMID:26755705) UniProt PMID:26755705 NCBI chrNW_004955555:1,959,702...1,985,679 JBrowse link
G Prkd2 protein kinase D2 involved_in ISO (PMID:20819079) UniProt PMID:20819079 NCBI chrNW_004955574:723,933...750,794
Ensembl chrNW_004955574:723,933...750,793 		JBrowse link
G Rab29 RAB29, member RAS oncogene family involved_in ISO (PMID:26021297) ParkinsonsUK-UCL PMID:26021297 NCBI chrNW_004955406:41,452,733...41,468,467
Ensembl chrNW_004955406:41,462,534...41,468,948 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:18045535) CAFA PMID:18045535 NCBI chrNW_004955422:19,602,930...19,612,263
Ensembl chrNW_004955422:19,603,345...19,611,516 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:18045535) CAFA PMID:18045535 NCBI chrNW_004955414:16,436,899...16,442,325
Ensembl chrNW_004955414:16,436,899...16,443,073 		JBrowse link
G Tespa1 thymocyte expressed, positive selection associated 1 involved_in ISO (PMID:22561606) UniProt PMID:22561606 NCBI chrNW_004955458:2,084,931...2,108,328
Ensembl chrNW_004955458:2,084,868...2,108,335 		JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 involved_in ISO (PMID:38225265) UniProt PMID:38225265 NCBI chrNW_004955437:8,678,212...8,780,700
Ensembl chrNW_004955437:8,677,801...8,782,120 		JBrowse link
positive regulation of toll-like receptor 13 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Treml4 triggering receptor expressed on myeloid cells like 4 involved_in ISO (PMID:25848864) UniProt PMID:25848864 NCBI chrNW_004955437:7,827,329...7,846,406 JBrowse link
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19865078) UniProt PMID:19865078 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:16267105) UniProt PMID:16267105 NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339 		JBrowse link
G LOC102004641 cytochrome b-245 light chain involved_in ISO (PMID:22423966) UniProt PMID:22423966 NCBI chrNW_004955541:2,570,843...2,573,822
Ensembl chrNW_004955541:2,569,727...2,574,118 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:26599367), (PMID:28471450) UniProt PMID:26599367 PMID:28471450 NCBI chrNW_004955463:4,900,115...4,993,793
Ensembl chrNW_004955463:4,900,060...4,993,793 		JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 involved_in ISO (PMID:28471450) UniProt PMID:28471450 NCBI chrNW_004955418:5,429,038...5,493,393
Ensembl chrNW_004955418:5,450,908...5,490,926 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) BHF-UCL PMID:19509286 NCBI chrNW_004955412:27,303,548...27,315,031
Ensembl chrNW_004955412:27,312,489...27,315,031 		JBrowse link
G Tlr1 toll like receptor 1 involved_in ISO (PMID:22198949) ARUK-UCL PMID:22198949 NCBI chrNW_004955443:8,442,419...8,450,318
Ensembl chrNW_004955443:8,447,956...8,450,382 		JBrowse link
positive regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004955432:22,258,262...22,292,403
Ensembl chrNW_004955432:22,258,250...22,292,403 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19865078) UniProt PMID:19865078 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
G Flot1 flotillin 1 involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004955583:717,246...729,924
Ensembl chrNW_004955583:713,560...729,924 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chrNW_004955424:20,212,077...20,263,761
Ensembl chrNW_004955424:20,211,600...20,263,761 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23871208) UniProt PMID:23871208 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:17322885) BHF-UCL PMID:17322885 NCBI chrNW_004955412:27,303,548...27,315,031
Ensembl chrNW_004955412:27,312,489...27,315,031 		JBrowse link
G Trim3 tripartite motif containing 3 involved_in ISO (PMID:32878999) UniProt PMID:32878999 NCBI chrNW_004955414:22,181,999...22,207,244
Ensembl chrNW_004955414:22,181,857...22,207,244 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in ISO (PMID:25736436) UniProt PMID:25736436 NCBI chrNW_004955453:10,101,576...10,148,205
Ensembl chrNW_004955453:10,101,576...10,149,710 		JBrowse link
positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISO (PMID:24380872) UniProt PMID:24380872 NCBI chrNW_004955418:73,736...75,345
Ensembl chrNW_004955418:73,897...75,224 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:18622013) UniProt PMID:18622013 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:16267105) UniProt PMID:16267105 NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339 		JBrowse link
G Ifi35 interferon induced protein 35 involved_in ISO (PMID:29038465) UniProt PMID:29038465 NCBI chrNW_004955451:16,790,998...16,798,993
Ensembl chrNW_004955451:16,790,383...16,802,664 		JBrowse link
G LOC102006100 TIR domain-containing adapter molecule 2 involved_in ISO (PMID:19412184)
(PMID:22685567) 		UniProt PMID:19412184 PMID:22685567 NCBI chrNW_004955408:35,342,733...35,382,821
Ensembl chrNW_004955408:35,374,508...35,382,314 		JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) UniProt PMID:20345905 NCBI chrNW_004955420:25,580,449...25,604,277
Ensembl chrNW_004955420:25,580,359...25,604,331 		JBrowse link
G Ninj1 ninjurin 1 involved_in ISO (PMID:25860173) UniProt PMID:25860173 NCBI chrNW_004955515:4,892,748...4,905,627
Ensembl chrNW_004955515:4,892,039...4,907,323 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1 group H member 3 involved_in ISO (PMID:18511497) BHF-UCL PMID:18511497 NCBI chrNW_004955422:940,310...954,170
Ensembl chrNW_004955422:940,310...949,049 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chrNW_004955424:20,212,077...20,263,761
Ensembl chrNW_004955424:20,211,600...20,263,761 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23871208) UniProt PMID:23871208 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Ticam2 toll like receptor adaptor molecule 2 involved_in ISO (PMID:22685567)
(PMID:19412184) 		UniProt PMID:19412184 PMID:22685567 NCBI chrNW_004955411:31,010,373...31,042,321 JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) BHF-UCL PMID:19509286 NCBI chrNW_004955412:27,303,548...27,315,031
Ensembl chrNW_004955412:27,312,489...27,315,031 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in ISO (PMID:25736436) UniProt PMID:25736436 NCBI chrNW_004955453:10,101,576...10,148,205
Ensembl chrNW_004955453:10,101,576...10,149,710 		JBrowse link
G Znrf1 zinc and ring finger 1 involved_in ISO (PMID:28593998) UniProt PMID:28593998 NCBI chrNW_004955484:2,468,392...2,566,539
Ensembl chrNW_004955484:2,468,392...2,566,539 		JBrowse link
positive regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3 X-linked involved_in ISO (PMID:30341167) UniProt PMID:30341167 NCBI chrNW_004955565:1,387,043...1,403,624
Ensembl chrNW_004955565:1,386,973...1,404,220 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23871208) UniProt PMID:23871208 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISO (PMID:21435586) UniProt PMID:21435586 NCBI chrNW_004955487:1,988,226...2,001,731
Ensembl chrNW_004955487:1,987,405...2,001,731 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:25238095), (PMID:32433612)
(PMID:21045126), (PMID:25238095) 		UniProt PMID:21045126 PMID:25238095 PMID:32433612 NCBI chrNW_004955482:2,327,137...2,343,980 JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:32433612) UniProt PMID:32433612 NCBI chrNW_004955531:207,614...293,127
Ensembl chrNW_004955531:267,216...293,127 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells like 4 involved_in ISO (PMID:25848864) UniProt PMID:25848864 NCBI chrNW_004955437:7,827,329...7,846,406 JBrowse link
positive regulation of toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3 X-linked involved_in ISO (PMID:30341167) UniProt PMID:30341167 NCBI chrNW_004955565:1,387,043...1,403,624
Ensembl chrNW_004955565:1,386,973...1,404,220 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:32433612) UniProt PMID:32433612 NCBI chrNW_004955482:2,327,137...2,343,980 JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:32433612) UniProt PMID:32433612 NCBI chrNW_004955531:207,614...293,127
Ensembl chrNW_004955531:267,216...293,127 		JBrowse link
positive regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23871208) UniProt PMID:23871208 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISO (PMID:21435586) UniProt PMID:21435586 NCBI chrNW_004955487:1,988,226...2,001,731
Ensembl chrNW_004955487:1,987,405...2,001,731 		JBrowse link
G Rtn4 reticulon 4 involved_in ISO (PMID:25917084) UniProt PMID:25917084 NCBI chrNW_004955424:28,061,346...28,125,838 JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:25238095)
(PMID:21045126), (PMID:21277849), (PMID:25238095) 		UniProt PMID:21045126 PMID:21277849 PMID:25238095 NCBI chrNW_004955482:2,327,137...2,343,980 JBrowse link
G Tlr9 toll like receptor 9 involved_in ISO (PMID:18931679) UniProt PMID:18931679 NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells like 4 involved_in ISO (PMID:25848864) UniProt PMID:25848864 NCBI chrNW_004955437:7,827,329...7,846,406 JBrowse link
G Zdhhc3 zDHHC palmitoyltransferase 3 involved_in ISO (PMID:38169466) UniProt PMID:38169466 NCBI chrNW_004955420:26,698,168...26,736,364
Ensembl chrNW_004955420:26,698,168...26,733,953 		JBrowse link
positive regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdi1 GDP dissociation inhibitor 1 involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chrNW_004955580:935,021...941,081
Ensembl chrNW_004955580:934,798...941,081 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 involved_in ISO (PMID:11584270) UniProt PMID:11584270 NCBI chrNW_004955405:38,629,691...38,645,202
Ensembl chrNW_004955405:38,629,691...38,645,202 		JBrowse link
G Lrch4 leucine rich repeats and calponin homology domain containing 4 involved_in ISO (PMID:16449650) UniProt PMID:16449650 NCBI chrNW_004955573:315,764...327,833
Ensembl chrNW_004955573:315,766...331,477 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) UniProt PMID:20728433 NCBI chrNW_004955507:2,805,782...2,918,664
Ensembl chrNW_004955507:2,801,970...2,918,670 		JBrowse link
regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd19 CD19 molecule involved_in ISO (PMID:9382888) UniProt PMID:9382888 NCBI chrNW_004955493:6,540,160...6,544,077 JBrowse link
G Fcmr Fc mu receptor involved_in ISO (PMID:28135254) UniProt PMID:28135254 NCBI chrNW_004955406:42,438,173...42,452,339
Ensembl chrNW_004955406:42,438,783...42,452,163 		JBrowse link
G Gcsam germinal center associated signaling and motility involved_in ISO (PMID:23299888) UniProt PMID:23299888 NCBI chrNW_004955427:12,524,261...12,533,773
Ensembl chrNW_004955427:12,524,654...12,536,645 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:11672542) UniProt PMID:11672542 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142 		JBrowse link
regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd47 CD47 molecule involved_in ISO PMID:21401967 ARUK-UCL PMID:21401967 RGD:13792533 NCBI chrNW_004955427:8,704,519...8,740,962 JBrowse link
G Csk C-terminal Src kinase ISO RGD PMID:9325302 RGD:2303720 NCBI chrNW_004955450:3,127,561...3,144,550
Ensembl chrNW_004955450:3,127,561...3,144,550 		JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in ISO PMID:18579528 UniProt PMID:18579528 RGD:2303650 NCBI chrNW_004955474:10,953,381...10,989,100 JBrowse link
G Pten phosphatase and tensin homolog ISO negative regulation RGD PMID:18056380 RGD:2292524 NCBI chrNW_004955425:5,007,811...5,091,829
Ensembl chrNW_004955425:5,014,147...5,091,829 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (PMID:17341663)
(PMID:15235600) 		MGI PMID:15235600 PMID:17341663 NCBI chrNW_004955456:8,648,925...8,716,337
Ensembl chrNW_004955456:8,674,469...8,718,821 		JBrowse link
regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf1 interferon regulatory factor 1 involved_in ISO (PMID:17018642) UniProt PMID:17018642 NCBI chrNW_004955408:3,882,282...3,887,965
Ensembl chrNW_004955408:3,880,155...3,887,973 		JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO (PMID:15800576) UniProt PMID:15800576 NCBI chrNW_004955476:11,442,781...11,445,706
Ensembl chrNW_004955476:11,443,272...11,445,657 		JBrowse link
regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf7 interferon regulatory factor 7 involved_in ISO (PMID:15800576) UniProt PMID:15800576 NCBI chrNW_004955476:11,442,781...11,445,706
Ensembl chrNW_004955476:11,443,272...11,445,657 		JBrowse link
regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in ISO (PMID:22801494) UniProt PMID:22801494 NCBI chrNW_004955441:4,908,318...4,944,343 JBrowse link
G Kcnk13 potassium two pore domain channel subfamily K member 13 involved_in ISO (PMID:35353387) UniProt PMID:35353387 NCBI chrNW_004955438:12,522,063...12,660,078
Ensembl chrNW_004955438:12,522,737...12,663,480 		JBrowse link
regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a2 solute carrier family 15 member 2 involved_in ISO (PMID:29784761) UniProt PMID:29784761 NCBI chrNW_004955427:21,221,778...21,255,725
Ensembl chrNW_004955427:21,221,750...21,255,725 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:29784761) UniProt PMID:29784761 NCBI chrNW_004955482:2,327,137...2,343,980 JBrowse link
regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chrNW_004955422:18,868,696...18,877,826
Ensembl chrNW_004955422:18,868,696...18,877,438 		JBrowse link
regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:27824081) UniProt PMID:27824081 NCBI chrNW_004955574:1,505,997...1,514,680
Ensembl chrNW_004955574:1,506,022...1,517,130 		JBrowse link
regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl10 BCL10 immune signaling adaptor acts_upstream_of_or_within ISO (PMID:14614861) MGI PMID:14614861 NCBI chrNW_004955423:8,710,231...8,720,530
Ensembl chrNW_004955423:8,709,890...8,722,050 		JBrowse link
G Cd300a CD300a molecule involved_in ISO (PMID:22046970) UniProt PMID:22046970 NCBI chrNW_004955553:1,335,854...1,356,001
Ensembl chrNW_004955553:1,336,227...1,460,376 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:14752163) MGI PMID:14752163 NCBI chrNW_004955452:10,608,317...10,632,310
Ensembl chrNW_004955452:10,608,318...10,632,310 		JBrowse link
G Malt1 MALT1 paracaspase acts_upstream_of_or_within ISO (PMID:14614861) MGI PMID:14614861 NCBI chrNW_004955402:42,919,480...42,968,873
Ensembl chrNW_004955402:42,911,649...42,972,429 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO (PMID:15661907) ARUK-UCL PMID:15661907 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (PMID:15917799) BHF-UCL PMID:15917799 NCBI chrNW_004955406:14,053,122...14,123,023
Ensembl chrNW_004955406:14,053,122...14,123,029 		JBrowse link
G Tespa1 thymocyte expressed, positive selection associated 1 acts_upstream_of ISO (PMID:28598420) MGI PMID:28598420 NCBI chrNW_004955458:2,084,931...2,108,328
Ensembl chrNW_004955458:2,084,868...2,108,335 		JBrowse link
regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flot2 flotillin 2 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004955481:4,276,847...4,298,523
Ensembl chrNW_004955481:4,276,860...4,298,523 		JBrowse link
G Hcfc2 host cell factor C2 acts_upstream_of_or_within ISO (PMID:28970238) MGI PMID:28970238 NCBI chrNW_004955405:38,729,700...38,758,398
Ensembl chrNW_004955405:38,730,054...38,760,115 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:37158982) UniProt PMID:37158982 NCBI chrNW_004955445:19,213,210...19,227,670
Ensembl chrNW_004955445:19,215,161...19,228,695 		JBrowse link
regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:27219021) UniProt PMID:27219021 NCBI chrNW_004955430:6,986,977...7,018,938
Ensembl chrNW_004955430:6,986,759...7,018,938 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (PMID:27219021) UniProt PMID:27219021 NCBI chrNW_004955405:39,503,020...39,540,069
Ensembl chrNW_004955405:39,503,020...39,540,335 		JBrowse link
G Flot1 flotillin 1 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004955583:717,246...729,924
Ensembl chrNW_004955583:713,560...729,924 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO (PMID:19289601) UniProt PMID:19289601 NCBI chrNW_004955446:1,020,707...1,098,327
Ensembl chrNW_004955446:1,020,043...1,098,820 		JBrowse link
regulation of toll-like receptor 6 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514) ARUK-UCL PMID:31134514 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697 		JBrowse link
regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268 		JBrowse link
G Cd36 CD36 molecule (CD36 blood group) involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313 		JBrowse link
G Esr1 estrogen receptor 1 acts_upstream_of_or_within ISO (PMID:22659029) MGI PMID:22659029 NCBI chrNW_004955439:9,588,631...9,953,606
Ensembl chrNW_004955439:9,588,201...9,963,353 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:20547752) UniProt PMID:20547752 NCBI chrNW_004955423:2,024,084...2,032,530
Ensembl chrNW_004955423:2,022,417...2,033,149 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:20616063) UniProt PMID:20616063 NCBI chrNW_004955463:4,900,115...4,993,793
Ensembl chrNW_004955463:4,900,060...4,993,793 		JBrowse link
RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clpb ClpB family mitochondrial disaggregase involved_in ISO (PMID:31522117) UniProt PMID:31522117 NCBI chrNW_004955414:18,968,144...19,106,241
Ensembl chrNW_004955414:18,967,435...19,106,241 		JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor acts_upstream_of_or_within ISO (PMID:22745163) MGI PMID:22745163 NCBI chrNW_004955468:3,799,897...3,863,241 JBrowse link
G Mavs mitochondrial antiviral signaling protein acts_upstream_of_or_within ISO (PMID:22745163) MGI PMID:22745163 NCBI chrNW_004955415:14,691,918...14,704,782
Ensembl chrNW_004955415:14,695,438...14,703,672 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in ISO (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chrNW_004955482:9,339,174...9,359,266 JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:31522117) UniProt PMID:31522117 NCBI chrNW_004955451:12,110,290...12,119,870
Ensembl chrNW_004955451:12,110,290...12,120,124 		JBrowse link
G Phb2 prohibitin 2 involved_in ISO (PMID:31522117) UniProt PMID:31522117 NCBI chrNW_004955413:4,557,969...4,563,697
Ensembl chrNW_004955413:4,558,259...4,563,582 		JBrowse link
G Rigi RNA sensor RIG-I involved_in ISO (PMID:19211564)
(PMID:28469175) 		UniProt PMID:19211564 PMID:28469175 NCBI chrNW_004955472:3,093,895...3,135,524
Ensembl chrNW_004955472:3,093,939...3,133,987 		JBrowse link
G Rnf135 ring finger protein 135 involved_in ISO (PMID:28469175), (PMID:31006531)
(PMID:21147464)
(PMID:21147464), (PMID:28469175)
(PMID:23950712) 		UniProt PMID:21147464 PMID:23950712 PMID:28469175 PMID:31006531 NCBI chrNW_004955481:7,111,760...7,122,800 JBrowse link
G Trim25 tripartite motif containing 25 NOT|involved_in ISO (PMID:31006531) UniProt PMID:31006531 NCBI chrNW_004955451:5,918,287...5,934,252
Ensembl chrNW_004955451:5,918,287...5,934,258 		JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcg2 phospholipase C gamma 2 involved_in ISO (PMID:19136564), (PMID:22041900) ARUK-UCL PMID:19136564 PMID:22041900 NCBI chrNW_004955522:4,352,890...4,480,735
Ensembl chrNW_004955522:4,358,233...4,468,986 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO (PMID:19136564) ARUK-UCL PMID:19136564 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chrNW_004955468:2,673,657...2,677,633
Ensembl chrNW_004955468:2,673,980...2,677,321 		JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tyrobp transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chrNW_004955468:2,673,657...2,677,633
Ensembl chrNW_004955468:2,673,980...2,677,321 		JBrowse link
T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:18305217) MGI PMID:18305217 NCBI chrNW_004955513:652,048...799,182
Ensembl chrNW_004955513:653,252...799,239 		JBrowse link
G Ada adenosine deaminase acts_upstream_of ISO (PMID:11435465) MGI PMID:11435465 NCBI chrNW_004955445:12,696,096...12,717,488
Ensembl chrNW_004955445:12,696,096...12,717,488 		JBrowse link
G Bcl10 BCL10 immune signaling adaptor involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004955423:8,710,231...8,720,530
Ensembl chrNW_004955423:8,709,890...8,722,050 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (PMID:18228248) MGI PMID:18228248 NCBI chrNW_004955494:2,567,238...2,712,708 JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 acts_upstream_of_or_within ISO (PMID:17028169) MGI PMID:17028169 NCBI chrNW_004955500:7,676,331...7,685,174
Ensembl chrNW_004955500:7,672,828...7,687,420 		JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 acts_upstream_of_or_within ISO (PMID:17028169) MGI PMID:17028169 NCBI chrNW_004955440:17,364,996...17,497,446
Ensembl chrNW_004955440:17,371,321...17,497,616 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (PMID:23793062) MGI PMID:23793062 NCBI chrNW_004955484:9,025,409...9,037,942
Ensembl chrNW_004955484:9,025,460...9,037,580 		JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within ISO (PMID:12697763) MGI PMID:12697763 NCBI chrNW_004955427:6,601,651...6,812,896
Ensembl chrNW_004955427:6,604,820...6,812,882 		JBrowse link
G Cd247 CD247 molecule acts_upstream_of_or_within
involved_in 		ISO (PMID:11435465)
(PMID:35271814) 		MGI
UniProt		 PMID:11435465 PMID:35271814 NCBI chrNW_004955462:9,466,706...9,539,897
Ensembl chrNW_004955462:9,469,255...9,538,882 		JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within ISO (PMID:23793062) MGI PMID:23793062 NCBI chrNW_004955457:11,159,769...11,253,099
Ensembl chrNW_004955457:11,162,282...11,192,991 		JBrowse link
G Cd2ap CD2 associated protein acts_upstream_of_or_within ISO (PMID:14512504) MGI PMID:14512504 NCBI chrNW_004955437:12,005,399...12,087,014
Ensembl chrNW_004955437:11,983,311...12,091,100 		JBrowse link
G Cd3e CD3e molecule acts_upstream_of_or_within
involved_in 		ISO (PMID:10485657)
(PMID:38614099) 		MGI
UniProt		 PMID:10485657 PMID:38614099 NCBI chrNW_004955412:19,464,666...19,476,425
Ensembl chrNW_004955412:19,464,613...19,478,990 		JBrowse link
G Cd8a CD8 subunit alpha involved_in ISO (PMID:17145893) ComplexPortal PMID:17145893 NCBI chrNW_004955424:952,595...979,159
Ensembl chrNW_004955424:952,502...978,636 		JBrowse link
G Cd8b CD8 subunit beta involved_in ISO (PMID:17145893) ComplexPortal PMID:17145893 NCBI chrNW_004955424:922,916...939,469 JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO (PMID:18305217) MGI PMID:18305217 NCBI chrNW_004955442:19,358,202...19,388,552
Ensembl chrNW_004955442:19,358,081...19,388,815 		JBrowse link
G Dennd1b DENN domain containing 1B involved_in ISO (PMID:26774822) UniProt PMID:26774822 NCBI chrNW_004955406:34,021,508...34,241,735
Ensembl chrNW_004955406:34,027,046...34,241,737 		JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004955482:5,380,121...5,388,588
Ensembl chrNW_004955482:5,380,121...5,388,588 		JBrowse link
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004955523:553,356...559,376
Ensembl chrNW_004955523:553,356...559,376 		JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004955464:13,254,228...13,378,832
Ensembl chrNW_004955464:13,254,228...13,378,832 		JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004955469:9,328,900...9,334,463
Ensembl chrNW_004955469:9,328,943...9,334,315 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004955420:23,313,405...23,322,748
Ensembl chrNW_004955420:23,309,378...23,322,698 		JBrowse link
G Fcho1 FCH and mu domain containing endocytic adaptor 1 involved_in ISO (PMID:32098969) UniProt PMID:32098969 NCBI chrNW_004955524:3,451,204...3,470,163
Ensembl chrNW_004955524:3,450,529...3,465,848 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:32610127) MGI PMID:32610127 NCBI chrNW_004955469:10,297,179...10,319,180
Ensembl chrNW_004955469:10,297,179...10,319,180 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:10072494), (PMID:11265635) MGI PMID:10072494 PMID:11265635 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Fyb2 FYN binding protein 2 involved_in ISO (PMID:27335501) UniProt PMID:27335501 NCBI chrNW_004955464:2,897,292...2,996,606
Ensembl chrNW_004955464:2,897,374...2,992,688 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:7722293) UniProt PMID:7722293 NCBI chrNW_004955411:36,403,156...36,597,660
Ensembl chrNW_004955411:36,401,842...36,512,054 		JBrowse link
G Gata3 GATA binding protein 3 involved_in ISO (PMID:20696860) UniProt PMID:20696860 NCBI chrNW_004955421:24,448,446...24,477,885
Ensembl chrNW_004955421:24,457,496...24,478,744 		JBrowse link
G Hras HRas proto-oncogene, GTPase acts_upstream_of_or_within ISO (PMID:21444916) MGI PMID:21444916 NCBI chrNW_004955476:11,508,446...11,510,333
Ensembl chrNW_004955476:11,508,126...11,510,333 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:21444916) MGI PMID:21444916 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
G Itk IL2 inducible T cell kinase involved_in ISO (PMID:10213685) UniProt PMID:10213685 NCBI chrNW_004955408:11,387,595...11,447,896
Ensembl chrNW_004955408:11,387,589...11,448,199 		JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 involved_in ISO (PMID:9045636) UniProt PMID:9045636 NCBI chrNW_004955452:10,413,883...10,458,518
Ensembl chrNW_004955452:10,413,883...10,440,678 		JBrowse link
G Lat linker for activation of T cells involved_in ISO (PMID:11368773), (PMID:25907557) UniProt PMID:11368773 PMID:25907557 NCBI chrNW_004955493:6,501,504...6,506,089
Ensembl chrNW_004955493:6,499,311...6,507,543 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:38614099), (PMID:8943371) UniProt PMID:8943371 PMID:38614099 NCBI chrNW_004955452:10,608,317...10,632,310
Ensembl chrNW_004955452:10,608,318...10,632,310 		JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 involved_in ISO (PMID:20551903) UniProt PMID:20551903 NCBI chrNW_004955408:23,200,137...23,246,032
Ensembl chrNW_004955408:23,200,828...23,245,771 		JBrowse link
G LOC102026469 HLA class II histocompatibility antigen, DP beta 1 chain involved_in ISO (PMID:32341563) UniProt PMID:32341563 NCBI chrNW_004955437:1,655,092...1,666,552
Ensembl chrNW_004955437:1,635,538...1,669,042 		JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:15125833)
(PMID:25282160) 		UniProt PMID:15125833 PMID:25282160 NCBI chrNW_004955402:42,919,480...42,968,873
Ensembl chrNW_004955402:42,911,649...42,972,429 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 acts_upstream_of_or_within ISO (PMID:9064344) MGI PMID:9064344 NCBI chrNW_004955442:17,284,232...17,380,026
Ensembl chrNW_004955442:17,284,232...17,380,020 		JBrowse link
G Nfkbid NFKB inhibitor delta involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chrNW_004955468:2,680,934...2,688,797
Ensembl chrNW_004955468:2,680,806...2,689,155 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chrNW_004955427:3,350,174...3,358,609
Ensembl chrNW_004955427:3,350,174...3,360,379 		JBrowse link
G Nras NRAS proto-oncogene, GTPase acts_upstream_of_or_within ISO (PMID:21444916) MGI PMID:21444916 NCBI chrNW_004955435:18,001,517...18,009,105
Ensembl chrNW_004955435:18,001,517...18,009,103 		JBrowse link
G Pde4b phosphodiesterase 4B involved_in ISO (PMID:17404263) BHF-UCL PMID:17404263 NCBI chrNW_004955423:24,464,503...24,906,409
Ensembl chrNW_004955423:24,463,953...24,906,394 		JBrowse link
G Pde4d phosphodiesterase 4D involved_in ISO (PMID:17404263) BHF-UCL PMID:17404263 NCBI chrNW_004955446:7,914,326...9,252,527
Ensembl chrNW_004955446:8,211,877...9,252,653 		JBrowse link
G Plcg1 phospholipase C gamma 1 acts_upstream_of_or_within ISO (PMID:15728238) MGI PMID:15728238 NCBI chrNW_004955445:15,787,496...15,823,859
Ensembl chrNW_004955445:15,787,496...15,823,859 		JBrowse link
G Plcg2 phospholipase C gamma 2 acts_upstream_of_or_within ISO (PMID:15728238) MGI PMID:15728238 NCBI chrNW_004955522:4,352,890...4,480,735
Ensembl chrNW_004955522:4,358,233...4,468,986 		JBrowse link
G Prkd2 protein kinase D2 involved_in ISO (PMID:17077180) BHF-UCL PMID:17077180 NCBI chrNW_004955574:723,933...750,794
Ensembl chrNW_004955574:723,933...750,793 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO (PMID:17698590) MGI PMID:17698590 NCBI chrNW_004955523:2,128,529...2,210,737
Ensembl chrNW_004955523:2,128,529...2,210,737 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (PMID:17698590) MGI PMID:17698590 NCBI chrNW_004955406:5,727,367...5,748,798
Ensembl chrNW_004955406:5,727,367...5,752,234 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 acts_upstream_of_or_within ISO (PMID:14752163) MGI PMID:14752163 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of ISO (PMID:9064344) MGI PMID:9064344 NCBI chrNW_004955413:4,525,954...4,547,177
Ensembl chrNW_004955413:4,525,954...4,547,177 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO PMID:12496963
(PMID:12496963)
(PMID:10358156) 		ARUK-UCL
UniProt		 PMID:10358156 PMID:12496963 RGD:1358565 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in ISO (PMID:20005846) UniProt PMID:20005846 NCBI chrNW_004955597:272,352...289,348
Ensembl chrNW_004955597:271,897...289,348 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chrNW_004955406:14,053,122...14,123,023
Ensembl chrNW_004955406:14,053,122...14,123,029 		JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chrNW_004955419:5,054,288...5,103,926
Ensembl chrNW_004955419:5,054,289...5,103,926 		JBrowse link
G Rftn1 raftlin, lipid raft linker 1 involved_in ISO (PMID:19414744) UniProt PMID:19414744 NCBI chrNW_004955430:8,605,057...8,801,187
Ensembl chrNW_004955430:8,603,401...8,779,896 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in 		ISO (PMID:11894098)
(PMID:21469090) 		MGI
UniProt		 PMID:11894098 PMID:21469090 NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228 		JBrowse link
G Rnf31 ring finger protein 31 involved_in ISO (PMID:20005846) UniProt PMID:20005846 NCBI chrNW_004955409:36,240,008...36,252,166
Ensembl chrNW_004955409:36,240,008...36,252,166 		JBrowse link
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO (PMID:24645804) MGI PMID:24645804 NCBI chrNW_004955419:28,423,354...28,555,948
Ensembl chrNW_004955419:28,421,354...28,558,823 		JBrowse link
G Siva1 SIVA1 apoptosis inducing factor involved_in ISO (PMID:16491128) HGNC-UCL PMID:16491128 NCBI chrNW_004955538:3,197,983...3,202,782 JBrowse link
G Skap1 src kinase associated phosphoprotein 1 involved_in ISO (PMID:11909961) UniProt PMID:11909961 NCBI chrNW_004955451:12,791,633...13,043,249
Ensembl chrNW_004955451:12,793,009...13,044,922 		JBrowse link
G Slc39a6 solute carrier family 39 member 6 involved_in ISO (PMID:34394081) UniProt PMID:34394081 NCBI chrNW_004955402:22,670,598...22,698,455
Ensembl chrNW_004955402:22,670,437...22,698,591 		JBrowse link
G Spn sialophorin involved_in ISO PMID:12496963 ARUK-UCL PMID:12496963 RGD:1358565 NCBI chrNW_004955493:7,256,505...7,258,607 JBrowse link
G Sppl3 signal peptide peptidase like 3 involved_in ISO (PMID:25384971) UniProt PMID:25384971 NCBI chrNW_004955455:10,849,627...10,905,515
Ensembl chrNW_004955455:10,760,804...10,907,024 		JBrowse link
G Stk11 serine/threonine kinase 11 acts_upstream_of_or_within ISO (PMID:21487392) MGI PMID:21487392 NCBI chrNW_004955495:6,678,195...6,699,408
Ensembl chrNW_004955495:6,678,195...6,699,058 		JBrowse link
G Stoml2 stomatin like 2 acts_upstream_of_or_within ISO (PMID:18641330) UniProt PMID:18641330 NCBI chrNW_004955472:1,079,261...1,082,632
Ensembl chrNW_004955472:1,079,578...1,082,486 		JBrowse link
G Themis thymocyte selection associated involved_in ISO (PMID:19597498), (PMID:19597499) UniProt PMID:19597498 PMID:19597499 NCBI chrNW_004955436:8,743,835...8,909,040 JBrowse link
G Themis2 thymocyte selection associated family member 2 acts_upstream_of_or_within ISO (PMID:22732588) MGI PMID:22732588 NCBI chrNW_004955452:7,058,703...7,075,114
Ensembl chrNW_004955452:7,058,662...7,075,463 		JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in ISO PMID:9285719 UniProt PMID:9285719 RGD:8554466 NCBI chrNW_004955412:20,480,284...20,484,958
Ensembl chrNW_004955412:20,480,284...20,484,958 		JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISO (PMID:11485735) UniProt PMID:11485735 NCBI chrNW_004955437:11,877,051...11,915,220
Ensembl chrNW_004955437:11,876,895...11,915,460 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:15125833)
(PMID:23514740) 		UniProt PMID:15125833 PMID:23514740 NCBI chrNW_004955422:9,925,765...9,950,354
Ensembl chrNW_004955422:9,932,680...9,949,100 		JBrowse link
G Txk TXK tyrosine kinase involved_in ISO (PMID:10213685) UniProt PMID:10213685 NCBI chrNW_004955443:474,099...556,697
Ensembl chrNW_004955443:474,099...556,697 		JBrowse link
G Ube2n ubiquitin conjugating enzyme E2 N involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004955405:30,240,402...30,278,362
Ensembl chrNW_004955405:30,240,408...30,278,360 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 involved_in ISO (PMID:27400149) BHF-UCL PMID:27400149 NCBI chrNW_004955454:6,228,492...6,358,690
Ensembl chrNW_004955454:6,228,492...6,358,637 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase 70kDa acts_upstream_of_or_within
involved_in 		ISO (PMID:9208839)
(PMID:38614099), (PMID:9489702) 		MGI
UniProt		 PMID:9208839 PMID:9489702 PMID:38614099 NCBI chrNW_004955470:4,379,260...4,397,851
Ensembl chrNW_004955470:4,386,311...4,396,419 		JBrowse link
G Zc3h12a zinc finger CCCH-type containing 12A involved_in ISO (PMID:23185455)
(PMID:25282160) 		UniProt PMID:23185455 PMID:25282160 NCBI chrNW_004955452:15,306,398...15,314,959
Ensembl chrNW_004955452:15,305,775...15,314,959 		JBrowse link
G Znf683 zinc finger protein 683 involved_in ISO (PMID:26179882) UniProt PMID:26179882 NCBI chrNW_004955452:5,748,569...5,758,389
Ensembl chrNW_004955452:5,748,639...5,754,911 		JBrowse link
TIRAP-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:11544529) BHF-UCL PMID:11544529 NCBI chrNW_004955412:27,303,548...27,315,031
Ensembl chrNW_004955412:27,312,489...27,315,031 		JBrowse link
toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339 		JBrowse link
G Irak1 interleukin 1 receptor associated kinase 1 involved_in
acts_upstream_of_or_within 		ISO (PMID:10383454)
(PMID:10549626) 		BHF-UCL
MGI		 PMID:10383454 PMID:10549626 NCBI chrNW_004955580:663,651...668,622
Ensembl chrNW_004955580:661,609...668,622 		JBrowse link
G Lgals9 galectin 9 NOT|involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chrNW_004955481:5,234,125...5,249,564 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of ISO (PMID:15220916) MGI PMID:15220916 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:22187460) UniProt PMID:22187460 NCBI chrNW_004955507:2,805,782...2,918,664
Ensembl chrNW_004955507:2,801,970...2,918,670 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (PMID:11894098) MGI PMID:11894098 NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228 		JBrowse link
G Tlr2 toll like receptor 2 involved_in ISO (PMID:17128265) BHF-UCL PMID:17128265 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO (PMID:16633345) UniProt PMID:16633345 NCBI chrNW_004955514:1,682,641...1,687,881 JBrowse link
toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd86 CD86 molecule involved_in ISO (PMID:25158758) UniProt PMID:25158758 NCBI chrNW_004955427:21,375,820...21,436,767
Ensembl chrNW_004955427:21,375,794...21,435,874 		JBrowse link
G Colec12 collectin subfamily member 12 involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004955402:9,445,419...9,614,956
Ensembl chrNW_004955402:9,468,421...9,614,286 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) UniProt PMID:22842346 NCBI chrNW_004955408:11,289,920...11,311,216
Ensembl chrNW_004955408:11,291,937...11,311,320 		JBrowse link
G Lgals9 galectin 9 involved_in ISO PMID:25158758 UniProt PMID:25158758 RGD:10054077 NCBI chrNW_004955481:5,234,125...5,249,564 JBrowse link
G Rftn1 raftlin, lipid raft linker 1 acts_upstream_of_or_within ISO (PMID:21266579) MGI PMID:21266579 NCBI chrNW_004955430:8,605,057...8,801,187
Ensembl chrNW_004955430:8,603,401...8,779,896 		JBrowse link
G Rnf170 ring finger protein 170 acts_upstream_of_or_within ISO (PMID:31076723) MGI PMID:31076723 NCBI chrNW_004955457:13,093,914...13,148,800
Ensembl chrNW_004955457:13,096,483...13,147,637 		JBrowse link
G Scara3 scavenger receptor class A member 3 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004955403:50,185,857...50,223,340
Ensembl chrNW_004955403:50,185,037...50,226,030 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:28098138) UniProt PMID:28098138 NCBI chrNW_004955467:10,547,706...10,578,355
Ensembl chrNW_004955467:10,547,294...10,578,387 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 involved_in ISO (PMID:12471095) UniProt PMID:12471095 NCBI chrNW_004955495:4,197,083...4,204,999
Ensembl chrNW_004955495:4,202,372...4,204,513 		JBrowse link
G Tlr3 toll like receptor 3 involved_in ISO (PMID:17128265), (PMID:18172197) UniProt PMID:17128265 PMID:18172197 NCBI chrNW_004955403:22,977,882...23,001,392
Ensembl chrNW_004955403:22,979,120...23,001,467 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO PMID:25158758 UniProt PMID:25158758 RGD:10054077 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO (PMID:16633345) UniProt PMID:16633345 NCBI chrNW_004955514:1,682,641...1,687,881 JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator involved_in ISO (PMID:18082565)
(PMID:16415873) 		UniProt PMID:16415873 PMID:18082565 NCBI chrNW_004955422:17,814,174...17,823,945
Ensembl chrNW_004955422:17,814,079...17,824,190 		JBrowse link
toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISO (PMID:27986454) UniProt PMID:27986454 NCBI chrNW_004955418:73,736...75,345
Ensembl chrNW_004955418:73,897...75,224 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex involved_in ISO (PMID:26189595) UniProt PMID:26189595 NCBI chrNW_004955507:6,066,026...6,102,066
Ensembl chrNW_004955507:6,067,203...6,102,001 		JBrowse link
G Ecsit ECSIT signaling integrator involved_in ISO (PMID:25371197) UniProt PMID:25371197 NCBI chrNW_004955495:2,375,992...2,385,962
Ensembl chrNW_004955495:2,375,602...2,382,035 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339 		JBrowse link
G Irak1 interleukin 1 receptor associated kinase 1 acts_upstream_of_or_within ISO (PMID:10549626) MGI PMID:10549626 NCBI chrNW_004955580:663,651...668,622
Ensembl chrNW_004955580:661,609...668,622 		JBrowse link
G Irak2 interleukin 1 receptor associated kinase 2 involved_in ISO (PMID:17878161) UniProt PMID:17878161 NCBI chrNW_004955561:1,585,842...1,650,268
Ensembl chrNW_004955561:1,585,827...1,653,197 		JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO (PMID:25636800) UniProt PMID:25636800 NCBI chrNW_004955559:1,223,986...1,228,671
Ensembl chrNW_004955559:1,224,874...1,228,624 		JBrowse link
G Letmd1 LETM1 domain containing 1 acts_upstream_of_or_within ISO (PMID:31980577) MGI PMID:31980577 NCBI chrNW_004955547:1,574,210...1,586,432
Ensembl chrNW_004955547:1,574,265...1,582,786 		JBrowse link
G Lgals9 galectin 9 NOT|involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chrNW_004955481:5,234,125...5,249,564 JBrowse link
G LOC102006100 TIR domain-containing adapter molecule 2 involved_in ISO (PMID:28630139) UniProt PMID:28630139 NCBI chrNW_004955408:35,342,733...35,382,821
Ensembl chrNW_004955408:35,374,508...35,382,314 		JBrowse link
G Ly96 lymphocyte antigen 96 involved_in ISO (PMID:24380872) UniProt PMID:24380872 NCBI chrNW_004955444:6,356,121...6,387,350
Ensembl chrNW_004955444:6,356,154...6,387,529 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:28098138) UniProt PMID:28098138 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:25371197) UniProt PMID:25371197 NCBI chrNW_004955411:17,177,335...17,229,957
Ensembl chrNW_004955411:17,177,335...17,229,957 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor involved_in ISO (PMID:16751103) UniProt PMID:16751103 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO (PMID:29624734) MGI PMID:29624734 NCBI chrNW_004955451:16,445,338...16,449,243
Ensembl chrNW_004955451:16,445,338...16,450,062 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in
acts_upstream_of_or_within 		ISO (PMID:7479976)
(PMID:18261938) 		UniProt
MGI		 PMID:7479976 PMID:18261938 NCBI chrNW_004955409:25,691,673...25,695,151
Ensembl chrNW_004955409:25,691,534...25,697,520 		JBrowse link
G Nmi N-myc and STAT interactor involved_in ISO (PMID:29038465) UniProt PMID:29038465 NCBI chrNW_004955440:16,850,469...16,877,295
Ensembl chrNW_004955440:16,848,108...16,877,674 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:22187458), (PMID:22187460) UniProt PMID:22187458 PMID:22187460 NCBI chrNW_004955507:2,805,782...2,918,664
Ensembl chrNW_004955507:2,801,970...2,918,670 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:25355951) UniProt PMID:25355951 NCBI chrNW_004955422:19,602,930...19,612,263
Ensembl chrNW_004955422:19,603,345...19,611,516 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (PMID:11894098) MGI PMID:11894098 NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228 		JBrowse link
G S100a14 S100 calcium binding protein A14 involved_in ISO (PMID:17625598) UniProt PMID:17625598 NCBI chrNW_004955545:261,483...263,689
Ensembl chrNW_004955545:261,323...264,374 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:28098138) UniProt PMID:28098138 NCBI chrNW_004955467:10,547,706...10,578,355
Ensembl chrNW_004955467:10,547,294...10,578,387 		JBrowse link
G Tbk1 TANK binding kinase 1 involved_in ISO (PMID:28747347) UniProt PMID:28747347 NCBI chrNW_004955458:11,210,120...11,263,632
Ensembl chrNW_004955458:11,211,398...11,263,867 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 involved_in ISO (PMID:12471095) UniProt PMID:12471095 NCBI chrNW_004955495:4,197,083...4,204,999
Ensembl chrNW_004955495:4,202,372...4,204,513 		JBrowse link
G Ticam2 toll like receptor adaptor molecule 2 involved_in ISO (PMID:28630139) UniProt PMID:28630139 NCBI chrNW_004955411:31,010,373...31,042,321 JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:16751103)
(PMID:11526399) 		UniProt
MGI		 PMID:11526399 PMID:16751103 NCBI chrNW_004955412:27,303,548...27,315,031
Ensembl chrNW_004955412:27,312,489...27,315,031 		JBrowse link
G Tlr4 toll like receptor 4 involved_in
acts_upstream_of_or_within 		ISO (PMID:10196138), (PMID:15618008), (PMID:18222170)
(PMID:28098138)
(PMID:25549946) 		UniProt
MGI		 PMID:10196138 PMID:15618008 PMID:18222170 PMID:25549946 PMID:28098138 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tmem126a transmembrane protein 126A acts_upstream_of_or_within ISO (PMID:25549946) MGI PMID:25549946 NCBI chrNW_004955414:7,214,408...7,224,499
Ensembl chrNW_004955414:7,216,286...7,224,475 		JBrowse link
G Tnip3 TNFAIP3 interacting protein 3 involved_in ISO (PMID:17088249) UniProt PMID:17088249 NCBI chrNW_004955428:19,479,633...19,511,738
Ensembl chrNW_004955428:19,479,638...19,511,758 		JBrowse link
G Traf3 TNF receptor associated factor 3 involved_in ISO (PMID:18222170) UniProt PMID:18222170 NCBI chrNW_004955538:1,954,152...2,013,367
Ensembl chrNW_004955538:1,954,152...2,013,367 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:25371197) UniProt PMID:25371197 NCBI chrNW_004955422:9,925,765...9,950,354
Ensembl chrNW_004955422:9,932,680...9,949,100 		JBrowse link
G Tril TLR4 interactor with leucine rich repeats involved_in ISO (PMID:19710467) UniProt PMID:19710467 NCBI chrNW_004955410:30,497,953...30,503,444
Ensembl chrNW_004955410:30,500,276...30,502,735 		JBrowse link
toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88 innate immune signal transduction adaptor involved_in ISO (PMID:16751103) UniProt PMID:16751103 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Tirap TIR domain containing adaptor protein NOT|involved_in ISO (PMID:12447442) BHF-UCL PMID:12447442 NCBI chrNW_004955412:27,303,548...27,315,031
Ensembl chrNW_004955412:27,312,489...27,315,031 		JBrowse link
G Tlr5 toll like receptor 5 involved_in ISO (PMID:14625549), (PMID:17128265) BHF-UCL PMID:14625549 PMID:17128265 NCBI chrNW_004955520:1,544,840...1,562,081
Ensembl chrNW_004955520:1,556,523...1,559,093 		JBrowse link
toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) UniProt PMID:22842346 NCBI chrNW_004955408:11,289,920...11,311,216
Ensembl chrNW_004955408:11,291,937...11,311,320 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:22187458) UniProt PMID:22187458 NCBI chrNW_004955507:2,805,782...2,918,664
Ensembl chrNW_004955507:2,801,970...2,918,670 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:28098138) UniProt PMID:28098138 NCBI chrNW_004955467:10,547,706...10,578,355
Ensembl chrNW_004955467:10,547,294...10,578,387 		JBrowse link
G Tlr7 toll like receptor 7 involved_in ISO (PMID:12032557)
(PMID:14976261) 		GO_Central
UniProt		 PMID:12032557 PMID:14976261 NCBI chrNW_004955544:424,897...443,562
Ensembl chrNW_004955544:424,850...443,564 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator involved_in ISO (PMID:19006693)
(PMID:16415873) 		UniProt PMID:16415873 PMID:19006693 NCBI chrNW_004955422:17,814,174...17,823,945
Ensembl chrNW_004955422:17,814,079...17,824,190 		JBrowse link
toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88 innate immune signal transduction adaptor involved_in ISO (PMID:33718825) UniProt PMID:33718825 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Tlr7 toll like receptor 7 involved_in ISO (PMID:12032557) GO_Central PMID:12032557 NCBI chrNW_004955544:424,897...443,562
Ensembl chrNW_004955544:424,850...443,564 		JBrowse link
G Tlr8 toll like receptor 8 involved_in ISO (PMID:12032557), (PMID:24942581), (PMID:33718825) UniProt PMID:12032557 PMID:24942581 PMID:33718825 NCBI chrNW_004955544:302,027...317,110
Ensembl chrNW_004955544:303,319...306,426 		JBrowse link
toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epg5 ectopic P-granules 5 autophagy tethering factor acts_upstream_of_positive_effect ISO (PMID:29130391) UniProt PMID:29130391 NCBI chrNW_004955402:31,422,848...31,532,189
Ensembl chrNW_004955402:31,422,848...31,532,289 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) UniProt PMID:22842346 NCBI chrNW_004955408:11,289,920...11,311,216
Ensembl chrNW_004955408:11,291,937...11,311,320 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1 group H member 4 involved_in ISO (PMID:23372731) UniProt PMID:23372731 NCBI chrNW_004955405:36,160,360...36,236,258
Ensembl chrNW_004955405:36,160,049...36,237,751 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:22187458), (PMID:22187460) UniProt PMID:22187458 PMID:22187460 NCBI chrNW_004955507:2,805,782...2,918,664
Ensembl chrNW_004955507:2,801,970...2,918,670 		JBrowse link
G Tlr9 toll like receptor 9 involved_in ISO (PMID:23857366) UniProt PMID:23857366 NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO (PMID:16633345) UniProt PMID:16633345 NCBI chrNW_004955514:1,682,641...1,687,881 JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator involved_in ISO (PMID:19006693)
(PMID:38169466)
(PMID:16415873) 		UniProt PMID:16415873 PMID:19006693 PMID:38169466 NCBI chrNW_004955422:17,814,174...17,823,945
Ensembl chrNW_004955422:17,814,079...17,824,190 		JBrowse link
toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3b1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within ISO (PMID:20847273) MGI PMID:20847273 NCBI chrNW_004955425:22,792,616...23,051,509
Ensembl chrNW_004955425:22,792,616...23,051,737 		JBrowse link
G Bcl10 BCL10 immune signaling adaptor involved_in ISO (PMID:16831874) UniProt PMID:16831874 NCBI chrNW_004955423:8,710,231...8,720,530
Ensembl chrNW_004955423:8,709,890...8,722,050 		JBrowse link
G Cd86 CD86 molecule acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chrNW_004955427:21,375,820...21,436,767
Ensembl chrNW_004955427:21,375,794...21,435,874 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:30990796) MGI PMID:30990796 NCBI chrNW_004955422:19,425,741...19,431,801
Ensembl chrNW_004955422:19,423,591...19,433,885 		JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 ISO RGD PMID:27832756 RGD:34888235 NCBI chrNW_004955458:12,839,995...12,880,285
Ensembl chrNW_004955458:12,846,237...12,879,316 		JBrowse link
G Lrrc19 leucine rich repeat containing 19 acts_upstream_of_or_within ISO (PMID:19679103) MGI PMID:19679103 NCBI chrNW_004955472:7,841,459...7,850,906
Ensembl chrNW_004955472:7,841,322...7,852,597 		JBrowse link
G Ly96 lymphocyte antigen 96 involved_in ISO (PMID:14607928) ComplexPortal PMID:14607928 NCBI chrNW_004955444:6,356,121...6,387,350
Ensembl chrNW_004955444:6,356,154...6,387,529 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 involved_in ISO (PMID:17906627) UniProt PMID:17906627 NCBI chrNW_004955406:42,231,858...42,276,477
Ensembl chrNW_004955406:42,231,858...42,276,477 		JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 involved_in ISO (PMID:17906627) UniProt PMID:17906627 NCBI chrNW_004955532:2,392,539...2,419,219
Ensembl chrNW_004955532:2,392,539...2,420,604 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:23728777)
(PMID:25124037) 		MGI PMID:23728777 PMID:25124037 NCBI chrNW_004955427:3,350,174...3,358,609
Ensembl chrNW_004955427:3,350,174...3,360,379 		JBrowse link
G Plcg2 phospholipase C gamma 2 involved_in ISO (PMID:19136564) ARUK-UCL PMID:19136564 NCBI chrNW_004955522:4,352,890...4,480,735
Ensembl chrNW_004955522:4,358,233...4,468,986 		JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 involved_in ISO (PMID:17906627) UniProt PMID:17906627 NCBI chrNW_004955509:600,415...701,833
Ensembl chrNW_004955509:600,284...701,837 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 involved_in ISO (PMID:12471095) UniProt PMID:12471095 NCBI chrNW_004955495:4,197,083...4,204,999
Ensembl chrNW_004955495:4,202,372...4,204,513 		JBrowse link
G Tlr1 toll like receptor 1 involved_in ISO (PMID:16893894) RGD
ComplexPortal		 PMID:16893894 PMID:16973131 RGD:1643119 NCBI chrNW_004955443:8,442,419...8,450,318
Ensembl chrNW_004955443:8,447,956...8,450,382 		JBrowse link
G Tlr2 toll like receptor 2 involved_in ISO (PMID:16893894) RGD
ComplexPortal		 PMID:16893894 PMID:16973131 PMID:18353287 RGD:1643119 RGD:5684896 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258 		JBrowse link
G Tlr3 toll like receptor 3 involved_in ISO (PMID:18172197) RGD
UniProt		 PMID:16973131 PMID:18172197 RGD:1643119 NCBI chrNW_004955403:22,977,882...23,001,392
Ensembl chrNW_004955403:22,979,120...23,001,467 		JBrowse link
G Tlr4 toll like receptor 4 involved_in ISO (PMID:14607928) RGD
ComplexPortal		 PMID:14607928 PMID:16973131 RGD:1643119 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tlr6 toll like receptor 6 ISO RGD PMID:16973131 PMID:18353287 RGD:1643119 RGD:5684896 NCBI chrNW_004955443:8,401,461...8,427,175
Ensembl chrNW_004955443:8,422,534...8,424,942 		JBrowse link
G Tlr9 toll like receptor 9 involved_in ISO (PMID:17128265) RGD
BHF-UCL		 PMID:16973131 PMID:17128265 RGD:1643119 NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582 		JBrowse link
G Traf3 TNF receptor associated factor 3 involved_in ISO (PMID:16306937)
(PMID:18222170) 		UniProt PMID:16306937 PMID:18222170 NCBI chrNW_004955538:1,954,152...2,013,367
Ensembl chrNW_004955538:1,954,152...2,013,367 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator acts_upstream_of_or_within ISO (PMID:16415873) MGI PMID:16415873 NCBI chrNW_004955422:17,814,174...17,823,945
Ensembl chrNW_004955422:17,814,079...17,824,190 		JBrowse link
toll-like receptor TLR1:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:28098138) UniProt PMID:28098138 NCBI chrNW_004955467:10,547,706...10,578,355
Ensembl chrNW_004955467:10,547,294...10,578,387 		JBrowse link
toll-like receptor TLR6:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88 innate immune signal transduction adaptor involved_in ISO (PMID:36964784) UniProt PMID:36964784 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:27708357) UniProt PMID:27708357 NCBI chrNW_004955422:19,602,930...19,612,263
Ensembl chrNW_004955422:19,603,345...19,611,516 		JBrowse link
G Tlr2 toll like receptor 2 involved_in ISO (PMID:23626692) ComplexPortal PMID:23626692 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258 		JBrowse link
G Tlr6 toll like receptor 6 involved_in ISO (PMID:23626692) ComplexPortal PMID:23626692 NCBI chrNW_004955443:8,401,461...8,427,175
Ensembl chrNW_004955443:8,422,534...8,424,942 		JBrowse link
TRAM-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102006100 TIR domain-containing adapter molecule 2 involved_in ISO (PMID:19412184)
(PMID:22685567) 		UniProt PMID:19412184 PMID:22685567 NCBI chrNW_004955408:35,342,733...35,382,821
Ensembl chrNW_004955408:35,374,508...35,382,314 		JBrowse link
G Prkce protein kinase C epsilon involved_in ISO (PMID:16757566) UniProt PMID:16757566 NCBI chrNW_004955441:12,642,703...13,142,396
Ensembl chrNW_004955441:12,642,697...13,139,372 		JBrowse link
G Rab11fip2 RAB11 family interacting protein 2 involved_in ISO (PMID:30883606) UniProt PMID:30883606 NCBI chrNW_004955431:22,637,605...22,674,107
Ensembl chrNW_004955431:22,634,103...22,674,107 		JBrowse link
G Ticam2 toll like receptor adaptor molecule 2 involved_in ISO (PMID:19412184)
(PMID:22685567) 		UniProt PMID:19412184 PMID:22685567 NCBI chrNW_004955411:31,010,373...31,042,321 JBrowse link
TRIF-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule involved_in ISO (PMID:36232715) UniProt PMID:36232715 NCBI chrNW_004955434:9,487,309...9,508,366
Ensembl chrNW_004955434:9,487,315...9,505,904 		JBrowse link
G Cd300lf CD300 molecule like family member f involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chrNW_004955553:1,596,406...1,610,479
Ensembl chrNW_004955553:1,488,501...1,610,555 		JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO (PMID:25636800) UniProt PMID:25636800 NCBI chrNW_004955559:1,223,986...1,228,671
Ensembl chrNW_004955559:1,224,874...1,228,624 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 involved_in ISO (PMID:25636800)
(PMID:17658277) 		CACAO
ParkinsonsUK-UCL		 PMID:17658277 PMID:25636800 NCBI chrNW_004955495:4,197,083...4,204,999
Ensembl chrNW_004955495:4,202,372...4,204,513 		JBrowse link
G Tlr4 toll like receptor 4 involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tlr6 toll like receptor 6 involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chrNW_004955443:8,401,461...8,427,175
Ensembl chrNW_004955443:8,422,534...8,424,942 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12627
    immune system process 2049
      activation of immune response 461
        immune response-activating signaling pathway 420
          immune response-activating cell surface receptor signaling pathway + 244
          innate immune response-activating signaling pathway + 255
Path 2
Term Annotations click to browse term
  biological_process 12627
    biological regulation 9093
      regulation of biological process 8792
        positive regulation of biological process 5695
          positive regulation of response to stimulus 2175
            positive regulation of immune response 627
              activation of immune response 461
                immune response-activating signaling pathway 420
                  immune response-activating cell surface receptor signaling pathway + 244
                  innate immune response-activating signaling pathway + 255
paths to the root