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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of B cell mediated immunity
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Accession:GO:0002714 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity.
Synonyms:exact_synonym: positive regulation of B lymphocyte mediated immunity;   up regulation of B cell mediated immunity;   upregulation of B cell mediated immunity
 narrow_synonym: activation of B cell mediated immunity;   stimulation of B cell mediated immunity



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positive regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
positive regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6275756|PMID:30548312) RGD PMID:30548312 MGI:6275756 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
positive regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer2 Fc epsilon receptor II acts_upstream_of_or_within ISO MGI:3583003 (MGI:67606|PMID:8041705) RGD PMID:8041705 MGI:67606 NCBI chr12:1,742,809...1,754,476
Ensembl chr12:1,742,815...1,754,476
JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:11934565 RGD:2303774 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086
JBrowse link
G Hpx hemopexin acts_upstream_of_or_within ISO MGI:2447193 (MGI:3807609|PMID:18641331) RGD PMID:18641331 MGI:3807609 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
JBrowse link
G Lta lymphotoxin alpha acts_upstream_of_or_within ISO MGI:104798 (MGI:3690573|PMID:9834074) RGD PMID:9834074 MGI:3690573 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:3529594 (MGI:3528786|PMID:15692051) RGD PMID:15692051 MGI:3528786 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (MGI:77753|PMID:8566034) RGD PMID:8566034 MGI:77753 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO MGI:104797 (MGI:3690573|PMID:9834074) RGD PMID:9834074 MGI:3690573 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
positive regulation of immunoglobulin mediated immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in ISO
IBA
(PMID:16831868)
PMID:21873635
RGD PMID:16831868 PMID:21873635 RGD:13792537 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IBA
(PMID:16831868)
PMID:21873635
RGD PMID:16831868 PMID:21873635 RGD:13792537 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) RGD PMID:12496423 MGI:3763508 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
positive regulation of immunoglobulin production in mucosal tissue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC688282 hypothetical protein LOC688282 involved_in ISO (MGI:6103709|PMID:28978694) RGD PMID:28978694 MGI:6103709 NCBI chr10:103,015,371...103,027,407
Ensembl chr10:103,016,505...103,027,407
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5009207|PMID:9973465)
Ensembl
RGD
PMID:9973465 GO_REF:0000107 MGI:5009207 NCBI chr13:77,248,865...77,252,308
Ensembl chr13:77,248,717...77,252,329
JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) RGD PMID:12496423 MGI:3763508 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 acts_upstream_of_or_within ISO (MGI:5009766|PMID:21255825) RGD PMID:21255825 MGI:5009766 NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060
JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within ISO (MGI:5009766|PMID:21255825) RGD PMID:21255825 MGI:5009766 NCBI chr19:39,021,308...39,023,535
Ensembl chr19:39,022,183...39,023,515
JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISS
ISO
GO_REF:0000024
(MGI:6393148|PMID:31806351)
UniProt
RGD
PMID:31806351 GO_REF:0000024 MGI:6393148 NCBI chr 4:120,392,812...120,415,616
Ensembl chr 4:120,366,542...120,415,616
JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISS
ISO
GO_REF:0000024
(MGI:6370097|PMID:28114273)
UniProt
RGD
PMID:28114273 GO_REF:0000024 MGI:6370097 NCBI chr 1:201,000,444...201,049,819
Ensembl chr 1:201,000,444...201,049,819
JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISO
ISS
(MGI:6370097|PMID:28114273)
GO_REF:0000024
RGD
UniProt
PMID:28114273 GO_REF:0000024 MGI:6370097 NCBI chr 1:69,099,531...69,107,145
Ensembl chr 1:69,099,539...69,107,145
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693
JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:4821506|PMID:20671152) RGD PMID:20671152 MGI:4821506 NCBI chr 4:7,524,887...7,576,663
Ensembl chr 4:7,525,004...7,576,548
JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (MGI:5468036|PMID:23306439), (MGI:5476381|PMID:23333305), (MGI:5490831|PMID:23333306) RGD PMID:23306439 PMID:23333305 PMID:23333306 MGI:5468036 MGI:5476381 MGI:5490831 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617
JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO
IBA
(PMID:29656893)
PMID:21873635
RGD PMID:29656893 PMID:21873635 RGD:13792537 NCBI chr 3:119,938,695...120,011,068
Ensembl chr 3:119,938,833...120,009,550
JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965
JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 2:35,294,956...35,301,865
Ensembl chr 2:35,295,859...35,302,346
JBrowse link
G Tfrc transferrin receptor involved_in ISS
ISO
GO_REF:0000024
(PMID:26642240)
UniProt
RGD
PMID:26642240 GO_REF:0000024 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23345425), (PMID:23760478)
(MGI:3041657|PMID:15077110), (MGI:3046005|PMID:15159415)
RGD PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 MGI:3041657 MGI:3046005 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:1342394|PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:1342394|PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (MGI:5462481|PMID:23241889) RGD PMID:23241889 MGI:5462481 NCBI chr14:76,833,194...76,911,304
Ensembl chr14:76,835,637...76,913,641
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO UniProtKB:Q9JK91 (MGI:1342394|PMID:10430621) RGD PMID:10430621 MGI:1342394 NCBI chr12:10,676,819...10,701,161
Ensembl chr12:10,676,764...10,701,066
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:14988498)
AgBase
RGD
PMID:14988498 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnfsf13 TNF superfamily member 13 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:14988498)
MGI:3038886 (MGI:3037416|PMID:14988498)
RGD PMID:14988498 PMID:21873635 MGI:3037416, RGD:13792537 NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042
JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in ISO (MGI:3777853|PMID:12023368) RGD PMID:12023368 MGI:3777853 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605
JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3037416|PMID:14988498)
RGD PMID:14988498 PMID:21873635 MGI:3037416, RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO MGI:107187 (MGI:1345885|PMID:10490661) RGD PMID:10490661 MGI:1345885 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO MGI:4127920 (MGI:5763555|PMID:25404367) RGD PMID:25404367 MGI:5763555 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845
JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO MGI:1857150 (MGI:62368|PMID:7688139) RGD PMID:7688139 MGI:62368 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd40 CD40 molecule involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2670820|PMID:12882831)
RGD PMID:12882831 PMID:21873635 MGI:2670820, RGD:13792537 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:2670820|PMID:12882831) RGD PMID:12882831 MGI:2670820 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO MGI:1857191 (MGI:87443|PMID:1830926) RGD PMID:1830926 MGI:87443 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2670820|PMID:12882831), (MGI:3037416|PMID:14988498)
RGD PMID:12882831 PMID:14988498 PMID:21873635 MGI:2670820 MGI:3037416, RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Mlh1 mutL homolog 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:1342394|PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:1342394|PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 involved_in ISO (MGI:5752090|PMID:26744420) RGD PMID:26744420 MGI:5752090 NCBI chr 1:181,622,708...181,624,996 JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:5752090|PMID:26744420) RGD PMID:26744420 MGI:5752090 NCBI chr 4:7,524,887...7,576,663
Ensembl chr 4:7,525,004...7,576,548
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO UniProtKB:Q9JK91 (MGI:1342394|PMID:10430621) RGD PMID:10430621 MGI:1342394 NCBI chr12:10,676,819...10,701,161
Ensembl chr12:10,676,764...10,701,066
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (MGI:85031|PMID:9015183) RGD PMID:9015183 MGI:85031 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within ISO MGI:2180194 (MGI:2670820|PMID:12882831) RGD PMID:12882831 MGI:2670820 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
positive regulation of type I hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase IMP RGD PMID:22228807 RGD:11040701 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G Fcer1a Fc epsilon receptor Ia acts_upstream_of_or_within ISO MGI:2383982 (MGI:86632|PMID:8252632) RGD PMID:8252632 MGI:86632 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:2384004 (MGI:3029067|PMID:14764707) RGD PMID:14764707 MGI:3029067 NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Fcgr2a Fc gamma receptor 2A acts_upstream_of_or_within ISO MGI:1861924 (MGI:2683749|PMID:9743367), (MGI:78617|PMID:8552190), (MGI:82508|PMID:8769481) RGD PMID:8552190 PMID:8769481 PMID:9743367 MGI:2683749 MGI:78617 MGI:82508 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 acts_upstream_of_or_within ISO (MGI:2683749|PMID:9743367), (MGI:2683928|PMID:6952213), (MGI:78617|PMID:8552190) RGD PMID:6952213 PMID:8552190 PMID:9743367 MGI:2683749 MGI:2683928 MGI:78617 Ensembl chr 6:132,389,370...132,393,397 JBrowse link
positive regulation of type IIa hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1861799 (MGI:2177393|PMID:11901193)
Ensembl
RGD
PMID:11901193 GO_REF:0000107 MGI:2177393 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:1857165|MGI:2384004 (MGI:2177393|PMID:11901193), (MGI:2383973|PMID:8976192), (MGI:2664488|PMID:11911824) RGD PMID:8976192 PMID:11901193 PMID:11911824 MGI:2177393 MGI:2383973 MGI:2664488 NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Fcgr1a Fc gamma receptor 1A acts_upstream_of_or_within ISO MGI:2664927 (MGI:2664488|PMID:11911824) RGD PMID:11911824 MGI:2664488 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
JBrowse link
G Fcgr2a Fc gamma receptor 2A acts_upstream_of_or_within ISO MGI:1861924 (MGI:2664488|PMID:11911824), (MGI:2683747|PMID:9834201) RGD PMID:9834201 PMID:11911824 MGI:2664488 MGI:2683747 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 acts_upstream_of_or_within ISO (MGI:2177393|PMID:11901193), (MGI:2683747|PMID:9834201) RGD PMID:9834201 PMID:11901193 MGI:2177393 MGI:2683747 Ensembl chr 6:132,389,370...132,393,397 JBrowse link
positive regulation of type III hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase IMP RGD PMID:22228807 RGD:11040701 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:1857165 (MGI:2383973|PMID:8976192) RGD PMID:8976192 MGI:2383973 NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Fcgr1a Fc gamma receptor 1A acts_upstream_of_or_within ISO MGI:2679238 (MGI:2679189|PMID:11911823) RGD PMID:11911823 MGI:2679189 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
JBrowse link
G Fcgr2a Fc gamma receptor 2A acts_upstream_of_or_within ISO MGI:1861924 (MGI:82508|PMID:8769481) RGD PMID:8769481 MGI:82508 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20050
    immune system process 2566
      immune effector process 682
        leukocyte mediated immunity 447
          lymphocyte mediated immunity 333
            positive regulation of lymphocyte mediated immunity 131
              positive regulation of B cell mediated immunity 51
                helper T cell enhancement of B cell mediated immune response 0
                positive regulation of B cell cytokine production 0
                positive regulation of immunoglobulin mediated immune response + 51
                positive regulation of peripheral B cell anergy 0
                positive regulation of peripheral B cell deletion 0
Path 2
Term Annotations click to browse term
  biological_process 20050
    biological regulation 13942
      regulation of biological process 13176
        regulation of immune system process 1540
          positive regulation of immune system process 1072
            positive regulation of immune effector process 292
              positive regulation of leukocyte mediated immunity 157
                positive regulation of lymphocyte mediated immunity 131
                  positive regulation of B cell mediated immunity 51
                    helper T cell enhancement of B cell mediated immune response 0
                    positive regulation of B cell cytokine production 0
                    positive regulation of immunoglobulin mediated immune response + 51
                    positive regulation of peripheral B cell anergy 0
                    positive regulation of peripheral B cell deletion 0
paths to the root