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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of production of molecular mediator of immune response
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Accession:GO:0002701 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response.
Synonyms:exact_synonym: down regulation of production of molecular mediator of immune response;   downregulation of production of molecular mediator of immune response
 narrow_synonym: inhibition of production of molecular mediator of immune response


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negative regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink5 serine peptidase inhibitor, Kazal type 5 involved_in ISO (MGI:3770082|PMID:17012259) RGD PMID:17012259 MGI:3770082 NCBI chr18:35,118,300...35,190,458
Ensembl chr18:35,121,967...35,191,069
Ensembl chr 1:35,121,967...35,191,069
JBrowse link
negative regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4437182|PMID:20060382)
Ensembl
RGD
PMID:20060382 GO_REF:0000107 MGI:4437182 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO (PMID:12458630) RGD PMID:12458630 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:12458630) RGD PMID:12458630 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Il10 interleukin 10 involved_in ISS
ISO
GO_REF:0000024
(PMID:10443688)
UniProt
RGD
PMID:10443688 GO_REF:0000024 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10443688) RGD PMID:10443688 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
negative regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak3 Janus kinase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3719947|PMID:16020505)
BHF-UCL
RGD
PMID:16020505 GO_REF:0000024 MGI:3719947 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668
JBrowse link
negative regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 molecule involved_in ISO UniProtKB:Q80ZE3 (MGI:4453395|PMID:20200274) RGD PMID:20200274 MGI:4453395 NCBI chr 1:89,313,475...89,329,902
Ensembl chr 1:89,314,558...89,329,418
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb acts_upstream_of_or_within ISO MGI:1857166 (MGI:3608295|PMID:12385742) RGD PMID:12385742 MGI:3608295 NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2653910 (MGI:3589858|PMID:15944273)
Ensembl
RGD
PMID:15944273 GO_REF:0000107 MGI:3589858 NCBI chr  X:118,443,955...118,514,716
Ensembl chr  X:118,443,823...118,513,061
JBrowse link
G Il33 interleukin 33 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P08226 (MGI:3775141|PMID:18268038)
Ensembl
RGD
PMID:18268038 GO_REF:0000107 MGI:3775141 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit IMP RGD PMID:22981234 RGD:8696027 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 involved_in ISO UniProtKB:P35329 (MGI:4453395|PMID:20200274) RGD PMID:20200274 MGI:4453395 NCBI chr 1:98,512,663...98,521,736
Ensembl chr 1:98,512,625...98,521,706
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (MGI:3840374|PMID:19328063) RGD PMID:19328063 MGI:3840374 NCBI chr 7:141,039,433...141,070,269
Ensembl chr 7:141,034,982...141,069,989
JBrowse link
G Zpbp2 zona pellucida binding protein 2 acts_upstream_of_or_within ISO MGI:3762590 (MGI:6150730|PMID:29536159) RGD PMID:29536159 MGI:6150730 NCBI chr10:86,513,645...86,523,375
Ensembl chr10:86,514,830...86,523,372
JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly (ADP-ribose) polymerase family, member 3 involved_in ISO (MGI:6214451|PMID:26000965) RGD PMID:26000965 MGI:6214451 NCBI chr 8:115,173,440...115,179,543
Ensembl chr 8:115,173,453...115,179,191
JBrowse link
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Da2-19 uncharacterized LOC302729 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:48,196,789...48,213,506
Ensembl chr  X:48,196,916...48,213,505
JBrowse link
G Thoc1 THO complex 1 involved_in ISO (MGI:5520039|PMID:22144908) RGD PMID:22144908 MGI:5520039 NCBI chr18:1,142,540...1,177,084
Ensembl chr18:1,142,782...1,176,974
JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:103034|MGI:2158438 (MGI:1345885|PMID:10490661) RGD PMID:10490661 MGI:1345885 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:3696705 (MGI:3695768|PMID:16275384) RGD PMID:16275384 MGI:3695768 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO MGI:3695433 (MGI:3694584|PMID:17137798) RGD PMID:17137798 MGI:3694584 NCBI chr18:31,574,759...31,625,286
Ensembl chr18:31,574,821...31,625,274
JBrowse link
negative regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cuedc2 CUE domain containing 2 acts_upstream_of_or_within ISO MGI:5635142 (MGI:5576401|PMID:24882011)
(PMID:24882011)
RGD PMID:24882011 MGI:5576401 NCBI chr 1:266,078,107...266,087,057
Ensembl chr 1:266,078,108...266,086,299
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO (MGI:2183694|PMID:12150927) RGD PMID:12150927 MGI:2183694 NCBI chr 7:64,922,830...64,982,224
Ensembl chr 7:64,923,615...64,982,281
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS
(PMID:20875417)
GO_REF:0000024
RGD
AgBase
PMID:20875417 GO_REF:0000024 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:20875417)
AgBase
RGD
PMID:20875417 GO_REF:0000024 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO
ISS
(PMID:20875417)
GO_REF:0000024
RGD
AgBase
PMID:20875417 GO_REF:0000024 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
negative regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158436 (MGI:3581006|PMID:15950739) RGD PMID:15950739 MGI:3581006 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd96 CD96 molecule acts_upstream_of_or_within ISO MGI:5617136 (MGI:5569209|PMID:24658051) RGD PMID:24658051 MGI:5569209 NCBI chr11:57,108,757...57,183,855
Ensembl chr11:57,108,956...57,183,270
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
negative regulation of plasmacytoid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bst2 bone marrow stromal cell antigen 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:19564354)
UniProt
RGD
PMID:19564354 GO_REF:0000024 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
JBrowse link
negative regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in ISO (PMID:15466453), (PMID:23169781) RGD PMID:15466453 PMID:23169781 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Hfe homeostatic iron regulator involved_in ISO UniProtKB:P04439 (PMID:24643698) RGD PMID:24643698 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:18420485) RGD PMID:18420485 NCBI chr 1:73,393,854...73,399,448
Ensembl chr 1:73,393,850...73,399,579
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (MGI:5700313|PMID:11477403) RGD PMID:11477403 MGI:5700313 NCBI chr13:90,184,545...90,219,170
Ensembl chr13:90,184,569...90,219,217
JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO
GO_REF:0000107
(MGI:5634593|PMID:25642768)
Ensembl
RGD
PMID:25642768 GO_REF:0000107 MGI:5634593 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Vsir V-set immunoregulatory receptor acts_upstream_of_or_within ISO (MGI:5292805|PMID:21383057) RGD PMID:21383057 MGI:5292805 NCBI chr20:29,897,543...29,923,381
Ensembl chr20:29,897,594...29,919,998
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO (MGI:5908339|PMID:19360123) RGD PMID:19360123 MGI:5908339 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:5543347|PMID:23616576) RGD PMID:23616576 MGI:5543347 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    immune system process 2886
      production of molecular mediator of immune response 206
        negative regulation of production of molecular mediator of immune response 39
          negative regulation of antimicrobial peptide production + 1
          negative regulation of cytokine production involved in immune response + 26
          negative regulation of granzyme A production 0
          negative regulation of granzyme B production 0
          negative regulation of immunoglobulin production + 14
Path 2
Term Annotations click to browse term
  biological_process 19612
    biological regulation 13584
      regulation of biological process 12857
        negative regulation of biological process 5614
          negative regulation of metabolic process 3204
            negative regulation of macromolecule metabolic process 2975
              negative regulation of gene expression 1119
                negative regulation of production of molecular mediator of immune response 39
                  negative regulation of antimicrobial peptide production + 1
                  negative regulation of cytokine production involved in immune response + 26
                  negative regulation of granzyme A production 0
                  negative regulation of granzyme B production 0
                  negative regulation of immunoglobulin production + 14
paths to the root