positive regulation of immune effector process - Ontology Report

(PMID:16339535)

PMID:16339535

NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674

Enpp3

ectonucleotide pyrophosphatase/phosphodiesterase 3

involved_in

GO_REF:0000024
GO_REF:0000107
(MGI:5660449|PMID:25692702)

PMID:25692702

GO_REF:0000024 GO_REF:0000107 MGI:5660449

NCBI chr 1:20,563,700...20,635,044
Ensembl chr 1:20,563,697...20,635,041

Fer

FER tyrosine kinase

involved_in

GO_REF:0000024
(MGI:3694314|PMID:16731527)

PMID:16731527

GO_REF:0000024 MGI:3694314

NCBI chr 9:103,520,452...103,827,364
Ensembl chr 9:103,520,493...103,821,451

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

involved_in

GO_REF:0000107
(MGI:6827314|PMID:10026201)

PMID:10026201

GO_REF:0000107 MGI:6827314

NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984

positive regulation of activation of membrane attack complex

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

complement C3

involved_in

GO_REF:0000107
(MGI:4430818|PMID:15611275)

PMID:15611275

GO_REF:0000107 MGI:4430818

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

complement C6

involved_in

(MGI:4430818|PMID:15611275)

PMID:15611275

MGI:4430818

NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275

positive regulation of antibacterial peptide biosynthetic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

nucleotide-binding oligomerization domain containing 2

acts_upstream_of_or_within

(PMID:18167348)

PMID:18167348

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

positive regulation of antibacterial peptide production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Klk1c10

kallikrein 1-related peptidase C10

involved_in

(PMID:18714013)

PMID:18714013

NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052

Klk5

kallikrein related-peptidase 5

involved_in

(PMID:17012259)
GO_REF:0000033

PMID:17012259

GO_REF:0000033

NCBI chr 1:94,296,574...94,304,768
Ensembl chr 1:94,296,168...94,304,666

Klk7

kallikrein-related peptidase 7

involved_in

GO_REF:0000107
(PMID:17012259)

PMID:17012259

GO_REF:0000107

NCBI chr 1:94,267,170...94,271,361
Ensembl chr 1:94,266,605...94,271,332

Pgc

progastricsin

involved_in

(PMID:12759353)

PMID:12759353

NCBI chr 9:13,257,462...13,265,682
Ensembl chr 9:13,257,462...13,265,682

positive regulation of antibody-dependent cellular cytotoxicity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RT1 class Ia, locus A2

involved_in

(PMID:30134159)

PMID:30134159

NCBI chr20:4,870,939...4,910,183

positive regulation of antimicrobial peptide production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Il17a

interleukin 17A

involved_in

GO_REF:0000107
(MGI:3828868|PMID:19144317)

PMID:19144317

GO_REF:0000107 MGI:3828868

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

Il17f

interleukin 17F

involved_in

GO_REF:0000107
(MGI:3828868|PMID:19144317)

PMID:19144317

GO_REF:0000107 MGI:3828868

NCBI chr 9:23,190,094...23,201,482
Ensembl chr 9:23,190,100...23,201,482

positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

nucleotide-binding oligomerization domain containing 2

acts_upstream_of_or_within

MGI:3529594 (PMID:15692051)

PMID:15692051

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ifng

interferon gamma

involved_in

(PMID:20209097)

PMID:20209097

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

Lgals9

galectin 9

involved_in

(PMID:20209097)

PMID:20209097

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

positive regulation of complement activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

complement C6

involved_in

(MGI:4430818|PMID:15611275)

PMID:15611275

MGI:4430818

NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275

Il1b

interleukin 1 beta

involved_in

RNAcentral:URS0000424278_9606 (PMID:29384235)

PMID:29384235

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

Mbl2

mannose binding lectin 2

RGD

PMID:9920905

RGD:4889148

NCBI chr 1:228,016,439...228,024,736

Phb1

prohibitin 1

involved_in

(PMID:17070910)

PMID:17070910

NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042

positive regulation of complement activation, classical pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Trem2

triggering receptor expressed on myeloid cells 2

involved_in

(MGI:6275756|PMID:30548312)

PMID:30548312

MGI:6275756

NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170

positive regulation of cytokine production involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Clec7a

C-type lectin domain containing 7A

involved_in

(MGI:5803730|PMID:27288407)
GO_REF:0000033

PMID:27288407

GO_REF:0000033 MGI:5803730

NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897

Defb43

defensin beta 43

involved_in

(PMID:26649771)

PMID:26649771

NCBI chr15:37,271,888...37,276,782
Ensembl chr15:37,272,008...37,276,626

F2rl1

F2R like trypsin receptor 1

involved_in

GO_REF:0000024
(PMID:11441110)

PMID:11441110

GO_REF:0000024

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

Ffar2

free fatty acid receptor 2

involved_in

GO_REF:0000024
(MGI:5575446|PMID:23665276)

PMID:23665276

GO_REF:0000024 MGI:5575446

NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033

Ffar3

free fatty acid receptor 3

involved_in

GO_REF:0000024
(MGI:5575446|PMID:23665276)

PMID:23665276

GO_REF:0000024 MGI:5575446

NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849

Hk1

hexokinase 1

involved_in

(MGI:5790524|PMID:27374331)
GO_REF:0000107

PMID:27374331

GO_REF:0000107 MGI:5790524

NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131

Htr2a

5-hydroxytryptamine receptor 2A

RGD

PMID:19318092

RGD:401901206

NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928

Inava

innate immunity activator

involved_in

(PMID:28436939)

PMID:28436939

NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729

Irf5

interferon regulatory factor 5

involved_in

(PMID:29046356)

PMID:29046356

NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267

Lacc1

laccase domain containing 1

involved_in

(PMID:28593945)

PMID:28593945

NCBI chr15:52,390,267...52,407,630
Ensembl chr15:52,395,183...52,407,545

Laptm5

lysosomal protein transmembrane 5

involved_in

(MGI:6391873|PMID:22733818)

PMID:22733818

MGI:6391873

NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807

NLR family, pyrin domain containing 3

involved_in

(MGI:5790524|PMID:27374331)

PMID:27374331

MGI:5790524

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

nucleotide-binding oligomerization domain containing 2

involved_in

(PMID:16260731)

PMID:16260731

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

Scimp

SLP adaptor and CSK interacting membrane protein

involved_in

(MGI:5803730|PMID:27288407)

PMID:27288407

MGI:5803730

NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171

Sphk2

sphingosine kinase 2

involved_in

(MGI:3703830|PMID:17346996)

PMID:17346996

MGI:3703830

NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391

Tek

TEK receptor tyrosine kinase

acts_upstream_of_or_within

(PMID:20060382)

PMID:20060382

NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804

Tnfrsf14

TNF receptor superfamily member 14

involved_in
acts_upstream_of_or_within

GO_REF:0000033
MGI:4940320 (PMID:21236258)

PMID:21236258

GO_REF:0000033

NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703

Trim6

tripartite motif containing 6

involved_in

(PMID:24882218)

PMID:24882218

NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914

Wnt5a

Wnt family member 5A

involved_in

(PMID:18174455)

PMID:18174455

NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234

positive regulation of dendritic cell cytokine production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Clec7a

C-type lectin domain containing 7A

involved_in

(MGI:3844414|PMID:19136564), (MGI:5803730|PMID:27288407)

PMID:19136564 PMID:27288407

MGI:3844414 MGI:5803730

NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897

Kit

KIT proto-oncogene receptor tyrosine kinase

involved_in

(MGI:3796803|PMID:18454155)

PMID:18454155

MGI:3796803

NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652

nucleotide-binding oligomerization domain containing 2

RGD

PMID:16818757

RGD:1600784

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

Plcg2

phospholipase C, gamma 2

involved_in

GO_REF:0000107
(MGI:3844414|PMID:19136564)

PMID:19136564

GO_REF:0000107 MGI:3844414

NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930

Scimp

SLP adaptor and CSK interacting membrane protein

involved_in

(MGI:5803730|PMID:27288407)

PMID:27288407

MGI:5803730

NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171

positive regulation of eosinophil degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

F2rl1

F2R like trypsin receptor 1

involved_in

(PMID:11714832)

PMID:11714832

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

Stx4

syntaxin 4

involved_in

(PMID:16677249)

PMID:16677249

NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979

positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Appl2

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2

involved_in

(MGI:6271154|PMID:25568335)

PMID:25568335

MGI:6271154

NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754

positive regulation of granzyme A production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

X-C motif chemokine ligand 1

involved_in

(PMID:18832695)

PMID:18832695

NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329

positive regulation of granzyme B production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd244

CD244 molecule

involved_in

(PMID:11714776)

PMID:11714776

NCBI chr13:84,051,339...84,082,864
Ensembl chr13:84,052,493...84,074,492

Ptpn22

protein tyrosine phosphatase, non-receptor type 22

involved_in

(MGI:5562517|PMID:23871208)

PMID:23871208

MGI:5562517

NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779

X-C motif chemokine ligand 1

involved_in

(PMID:18832695)

PMID:18832695

NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329

positive regulation of histamine secretion by mast cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Nppa

natriuretic peptide A

involved_in

PMID:9663691

UniProt

PMID:9663691

RGD:13461752

NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351

Pla2g3

phospholipase A2, group III

involved_in

(PMID:23624557)
(MGI:5492190|PMID:23624557)

PMID:23624557

MGI:5492190

NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913

Snx4

sorting nexin 4

involved_in

(PMID:18253931)

PMID:18253931

NCBI chr11:67,460,872...67,518,143
Ensembl chr11:67,460,870...67,518,174

Vamp7

vesicle-associated membrane protein 7

involved_in

(PMID:18253931)

PMID:18253931

NCBI chr12:16,728,486...16,764,261
Ensembl chr12:16,728,524...16,764,097

Vamp8

vesicle-associated membrane protein 8

involved_in

GO_REF:0000107
(PMID:18253931)

PMID:18253931

GO_REF:0000107

NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897

positive regulation of humoral immune response mediated by circulating immunoglobulin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fcer2

Fc epsilon receptor II

acts_upstream_of_or_within

MGI:3583003 (PMID:8041705)

PMID:8041705

NCBI chr12:1,742,809...1,754,476
Ensembl chr12:1,742,815...1,754,476

Gimap5

GTPase, IMAP family member 5

RGD

PMID:11934565

RGD:2303774

NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086

Hpx

hemopexin

acts_upstream_of_or_within

MGI:2447193 (PMID:18641331)

PMID:18641331

NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328

Lta

lymphotoxin alpha

acts_upstream_of_or_within

MGI:104798 (PMID:9834074)

PMID:9834074

NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859

nucleotide-binding oligomerization domain containing 2

acts_upstream_of_or_within

MGI:3529594 (PMID:15692051)

PMID:15692051

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

protein tyrosine phosphatase, receptor type, C

acts_upstream_of_or_within

MGI:2181288 (PMID:8566034)

PMID:8566034

NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692

Tnf

tumor necrosis factor

acts_upstream_of_or_within

MGI:104797 (PMID:9834074)

PMID:9834074

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

positive regulation of immune complex clearance by monocytes and macrophages

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ccl2

C-C motif chemokine ligand 2

involved_in

(MGI:3840068|PMID:14566334)

PMID:14566334

MGI:3840068

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

Ccr2

C-C motif chemokine receptor 2

involved_in

GO_REF:0000024
(MGI:3840068|PMID:14566334)

BHF-UCL
RGD

PMID:14566334

GO_REF:0000024 MGI:3840068

NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100

Pla2g5

phospholipase A2, group V

involved_in

GO_REF:0000024
GO_REF:0000107
(MGI:5810005|PMID:20432503)
(PMID:20432503)

PMID:20432503

GO_REF:0000024 GO_REF:0000107 MGI:5810005

NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658

positive regulation of immunoglobulin mediated immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD226 molecule

involved_in

(PMID:16831868)
GO_REF:0000033

PMID:16831868

GO_REF:0000033

NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051

nectin cell adhesion molecule 2

involved_in

(PMID:16831868)
GO_REF:0000033

PMID:16831868

GO_REF:0000033

NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360

PVR cell adhesion molecule

involved_in

GO_REF:0000118

GO_REF:0000118

NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715

TNF superfamily member 4

involved_in

(MGI:3763508|PMID:12496423)

PMID:12496423

MGI:3763508

NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788

positive regulation of immunoglobulin production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Btk

Bruton tyrosine kinase

RGD

PMID:28352114

RGD:151665126

NCBI chr X:97,722,796...97,762,315
Ensembl chr X:97,722,802...97,761,853

Cd37

CD37 molecule

acts_upstream_of_or_within

MGI:2386160 (PMID:10891477)

PMID:10891477

NCBI chr 1:95,719,171...95,724,662
Ensembl chr 1:95,719,190...95,724,648

Cd86

CD86 molecule

involved_in

(MGI:5461234|PMID:23241883)

PMID:23241883

MGI:5461234

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

Clcf1

cardiotrophin-like cytokine factor 1

involved_in

(MGI:3777853|PMID:12023368)

PMID:12023368

MGI:3777853

NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605

Dnajb9

DnaJ heat shock protein family (Hsp40) member B9

involved_in

GO_REF:0000024
(MGI:5644772|PMID:25222125)

PMID:25222125

GO_REF:0000024 MGI:5644772

NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063

Ephb2

Eph receptor B2

involved_in

(PMID:24803541)

PMID:24803541

NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059

Foxp1

forkhead box P1

acts_upstream_of_or_within

MGI:3711150 (PMID:16819554)

PMID:16819554

NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258

Gpi

glucose-6-phosphate isomerase

involved_in

(PMID:3020690)

PMID:3020690

NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086

Hpx

hemopexin

acts_upstream_of_or_within

MGI:2447193 (PMID:18641331)

PMID:18641331

NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328

Il10

interleukin 10

acts_upstream_of

UniProtKB:P60568 (PMID:22962438)

PMID:22962438

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

Il13

interleukin 13

acts_upstream_of_or_within

IDA
ISO

IgE production after infection
MGI:1931804|MGI:96556 (PMID:15944273)

PMID:15944273 PMID:11573960

RGD:633067

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

Il13ra1

interleukin 13 receptor subunit alpha 1

IgE production after infection

RGD

PMID:11573960

RGD:633067

NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681
Ensembl chr11:115,348,860...115,408,681

Il2

interleukin 2

acts_upstream_of
acts_upstream_of_or_within

UniProtKB:P22301 (PMID:22962438)
MGI:1857191 (PMID:1830926)

PMID:1830926 PMID:22962438

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

Il21

interleukin 21

involved_in

GO_REF:0000024
(MGI:5450752|PMID:23045607)

PMID:23045607

GO_REF:0000024 MGI:5450752

NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996

Il33

interleukin 33

involved_in

GO_REF:0000107
UniProtKB:P08226 (MGI:3775141|PMID:18268038)

PMID:18268038

GO_REF:0000107 MGI:3775141

NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373

interleukin 4

acts_upstream_of_or_within

MGI:1857195|MGI:96541 (PMID:15944273)

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

Il4r

interleukin 4 receptor

acts_upstream_of_or_within

MGI:1861951 (PMID:15944273)

NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980

Il5

interleukin 5

involved_in

UniProtKB:Q8BVZ5 (MGI:3775141|PMID:18268038)

PMID:18268038

MGI:3775141

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

Il6

interleukin 6

involved_in

GO_REF:0000024
(MGI:5450752|PMID:23045607)
(PMID:3491322)

PMID:3491322 PMID:23045607

GO_REF:0000024 MGI:5450752

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

Mzb1

marginal zone B and B1 cell-specific protein

involved_in

GO_REF:0000024
(MGI:4366098|PMID:19805154), (MGI:4421284|PMID:19805157)

PMID:19805154 PMID:19805157

GO_REF:0000024 MGI:4366098 MGI:4421284

NCBI chr18:27,238,999...27,241,060
Ensembl chr18:27,239,001...27,241,094

Phb1

prohibitin 1

involved_in

GO_REF:0000024
(MGI:5461234|PMID:23241883)

PMID:23241883

GO_REF:0000024 MGI:5461234

NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042

Phb2

prohibitin 2

involved_in

GO_REF:0000024
GO_REF:0000107
(MGI:5461234|PMID:23241883)

PMID:23241883

GO_REF:0000024 GO_REF:0000107 MGI:5461234

NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272

protein tyrosine phosphatase, receptor type, C

involved_in

(PMID:1793833)

PMID:1793833

NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692

Rbp4

retinol binding protein 4

involved_in

(MGI:3796317|PMID:10944490)

PMID:10944490

MGI:3796317

NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399

RT1 class Ia, locus A2

involved_in

(PMID:25631937)

PMID:25631937

NCBI chr20:4,870,939...4,910,183

Sash3

SAM and SH3 domain containing 3

involved_in
acts_upstream_of_or_within

GO_REF:0000033
MGI:3716944 (PMID:16227612)

PMID:16227612

GO_REF:0000033

NCBI chr X:127,326,815...127,341,521
Ensembl chr X:127,326,859...127,341,519

Stx4

syntaxin 4

involved_in

(PMID:24055037)

PMID:24055037

NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979

Tlr9

toll-like receptor 9

involved_in

(PMID:23857366)

PMID:23857366

NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796

Tnfrsf4

TNF receptor superfamily member 4

involved_in

(MGI:74350|PMID:7749983)

PMID:7749983

MGI:74350

NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599

TNF superfamily member 4

involved_in

(MGI:74350|PMID:7749983)

PMID:7749983

MGI:74350

NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788

Vamp3

vesicle-associated membrane protein 3

NOT|involved_in

(PMID:24055037)

PMID:24055037

NCBI chr 5:161,498,109...161,508,704
Ensembl chr 5:161,498,109...161,508,751

Xbp1

X-box binding protein 1

involved_in

GO_REF:0000024
GO_REF:0000107
(MGI:5605956|PMID:12612580)
(PMID:11460154)

PMID:11460154 PMID:12612580

GO_REF:0000024 GO_REF:0000107 MGI:5605956

NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693

positive regulation of immunoglobulin production in mucosal tissue

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

C10h17orf99

smilar to human chromosome 17 open reading frame 99

involved_in

(MGI:6103709|PMID:28978694)

PMID:28978694

MGI:6103709

NCBI chr10:103,015,371...103,027,407
Ensembl chr10:103,016,505...103,027,407

X-C motif chemokine ligand 1

involved_in

GO_REF:0000107
(MGI:5009207|PMID:9973465)

PMID:9973465

GO_REF:0000107 MGI:5009207

NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329

positive regulation of interleukin-4-dependent isotype switching to IgE isotypes

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TNF superfamily member 4

involved_in

(MGI:3763508|PMID:12496423)

PMID:12496423

MGI:3763508

NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788

positive regulation of isotype switching

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Exosc3

exosome component 3

acts_upstream_of_or_within

(PMID:21255825)

PMID:21255825

NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060

Exosc6

exosome component 6

acts_upstream_of_or_within

(PMID:21255825)

PMID:21255825

NCBI chr19:39,022,171...39,023,585
Ensembl chr19:39,022,183...39,023,515

Hmces

5-hydroxymethylcytosine binding, ES cell specific

involved_in

GO_REF:0000024
(MGI:6393148|PMID:31806351)

PMID:31806351

GO_REF:0000024 MGI:6393148

NCBI chr 4:120,392,812...120,415,616
Ensembl chr 4:120,366,542...120,415,616

Kmt5b

lysine methyltransferase 5B

involved_in

GO_REF:0000024
(MGI:6370097|PMID:28114273)

PMID:28114273

GO_REF:0000024 MGI:6370097

NCBI chr 1:201,000,444...201,049,819
Ensembl chr 1:201,000,444...201,049,819

Kmt5c

lysine methyltransferase 5C

involved_in

(MGI:6370097|PMID:28114273)
GO_REF:0000024

PMID:28114273

GO_REF:0000024 MGI:6370097

NCBI chr 1:69,099,531...69,107,145
Ensembl chr 1:69,099,539...69,107,145

Mad2l2

mitotic arrest deficient 2 like 2

involved_in

(PMID:29656893)

NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693

Paxip1

PAX interacting protein 1

involved_in

(MGI:4821506|PMID:20671152)

PMID:20671152

MGI:4821506

NCBI chr 4:7,525,132...7,576,659
Ensembl chr 4:7,525,004...7,576,548

Rif1

replication timing regulatory factor 1

involved_in

(MGI:5468036|PMID:23306439), (MGI:5476381|PMID:23333305), (MGI:5490831|PMID:23333306)

PMID:23306439 PMID:23333305 PMID:23333306

MGI:5468036 MGI:5476381 MGI:5490831

NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617

Shld1

shieldin complex subunit 1

involved_in

(PMID:29656893)
GO_REF:0000033

GO_REF:0000033

NCBI chr 3:119,938,695...120,011,068
Ensembl chr 3:119,938,833...120,009,550

Shld2

shieldin complex subunit 2

involved_in

(PMID:29656893)

NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965

Shld3

shieldin complex subunit 3

involved_in

(PMID:29656893)

NCBI chr 2:35,297,255...35,302,071
Ensembl chr 2:35,295,859...35,302,346

Tfrc

transferrin receptor

involved_in

GO_REF:0000024
(PMID:26642240)

PMID:26642240

GO_REF:0000024

NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257

Tp53bp1

tumor protein p53 binding protein 1

involved_in

(PMID:23345425), (PMID:23760478)
(MGI:3041657|PMID:15077110), (MGI:3046005|PMID:15159415)

PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478

MGI:3041657 MGI:3046005

NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822

positive regulation of isotype switching to IgA isotypes

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Mlh1

mutL homolog 1

involved_in

GO_REF:0000107
(MGI:1342394|PMID:10430621)

GO_REF:0000107 MGI:1342394

NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617

Msh2

mutS homolog 2

involved_in

GO_REF:0000107
(MGI:1342394|PMID:10430621)

GO_REF:0000107 MGI:1342394

NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938

Nsd2

nuclear receptor binding SET domain protein 2

acts_upstream_of_or_within

(PMID:23241889)

PMID:23241889

NCBI chr14:76,833,179...76,911,304
Ensembl chr14:76,835,637...76,913,641

Pms2

PMS1 homolog 2, mismatch repair system component

involved_in

UniProtKB:Q9JK91 (MGI:1342394|PMID:10430621)

MGI:1342394

NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066

Tgfb1

transforming growth factor, beta 1

involved_in
acts_upstream_of_or_within

GO_REF:0000024
(PMID:14988498)

AgBase
RGD

PMID:14988498

GO_REF:0000024

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

Tnfsf12

TNF superfamily member 12

involved_in

GO_REF:0000118

GO_REF:0000118

NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213

Tnfsf13

TNF superfamily member 13

acts_upstream_of_or_within
involved_in

(PMID:14988498)
MGI:3038886 (PMID:14988498)
GO_REF:0000033

PMID:14988498

GO_REF:0000033

NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042

positive regulation of isotype switching to IgE isotypes

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Clcf1

cardiotrophin-like cytokine factor 1

involved_in

(MGI:3777853|PMID:12023368)

PMID:12023368

MGI:3777853

NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605

interleukin 4

acts_upstream_of_or_within

(PMID:14988498)

PMID:14988498

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

Stat6

signal transducer and activator of transcription 6

acts_upstream_of_or_within

MGI:107187 (PMID:10490661)

PMID:10490661

NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495

positive regulation of isotype switching to IgG isotypes

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Atad5

ATPase family, AAA domain containing 5

acts_upstream_of_or_within

MGI:4127920 (PMID:25404367)

PMID:25404367

NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845

Cd28

Cd28 molecule

acts_upstream_of_or_within

MGI:1857150 (PMID:7688139)

PMID:7688139

NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685

Cd40

CD40 molecule

acts_upstream_of_or_within

(PMID:12882831)

PMID:12882831

NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534

Ifng

interferon gamma

acts_upstream_of_or_within

(PMID:12882831)

PMID:12882831

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

Il2

interleukin 2

acts_upstream_of_or_within

MGI:1857191 (PMID:1830926)

PMID:1830926

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

interleukin 4

acts_upstream_of_or_within

(PMID:12882831), (PMID:14988498)

PMID:12882831 PMID:14988498

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

Mlh1

mutL homolog 1

involved_in

GO_REF:0000107
(MGI:1342394|PMID:10430621)

GO_REF:0000107 MGI:1342394

NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617

Msh2

mutS homolog 2

involved_in

GO_REF:0000107
(MGI:1342394|PMID:10430621)

GO_REF:0000107 MGI:1342394

NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938

Pagr1

Paxip1-associated glutamate-rich protein 1

involved_in

(MGI:5752090|PMID:26744420)

PMID:26744420

MGI:5752090

NCBI chr 1:181,622,698...181,625,024

Paxip1

PAX interacting protein 1

involved_in

(MGI:5752090|PMID:26744420)

PMID:26744420

MGI:5752090

NCBI chr 4:7,525,132...7,576,659
Ensembl chr 4:7,525,004...7,576,548

Pms2

PMS1 homolog 2, mismatch repair system component

involved_in

UniProtKB:Q9JK91 (MGI:1342394|PMID:10430621)

MGI:1342394

NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066

protein tyrosine phosphatase, receptor type, C

acts_upstream_of_or_within

MGI:2181288 (PMID:9015183)

PMID:9015183

NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692

Tbx21

T-box transcription factor 21

acts_upstream_of_or_within

MGI:2180194 (PMID:12882831)

PMID:12882831

NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831

positive regulation of leukocyte mediated cytotoxicity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ccl2

C-C motif chemokine ligand 2

RGD

PMID:8103296

RGD:8549560

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

positive regulation of macrophage cytokine production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Card9

caspase recruitment domain family, member 9

acts_upstream_of_or_within

MGI:3698412 (PMID:17187069)

PMID:17187069

NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237

Casp1

caspase 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(PMID:18490713)

PMID:18490713

GO_REF:0000107

NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383

Casp4

caspase 4

acts_upstream_of_or_within

MGI:1931465|MGI:2653833 (PMID:22002608)

PMID:22002608

NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092

Cd36

CD36 molecule

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2447190|MGI:3573941 (PMID:15690042), (PMID:16061696)

PMID:15690042 PMID:16061696

GO_REF:0000107

NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903

Cd74

CD74 molecule

involved_in

ISS
IEA
IBA
ISO

GO_REF:0000024
GO_REF:0000118
GO_REF:0000033
(MGI:4943655|PMID:19413900)

BHF-UCL
TreeGrafter
GO_Central
RGD

PMID:19413900

GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:4943655

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

Gprc5b

G protein-coupled receptor, class C, group 5, member B

involved_in

(MGI:5545939|PMID:23169819)

PMID:23169819

MGI:5545939

NCBI chr 1:173,316,904...173,340,933
Ensembl chr 1:173,316,907...173,340,932

Ifng

interferon gamma

acts_upstream_of_or_within

(PMID:9348310)

PMID:9348310

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

Laptm5

lysosomal protein transmembrane 5

involved_in

(MGI:6391873|PMID:22733818)

PMID:22733818

MGI:6391873

NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807

Mapkapk2

MAPK activated protein kinase 2

acts_upstream_of_or_within

(PMID:24020373)

PMID:24020373

NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457

Mir324

microRNA 324

acts_upstream_of_or_within

(PMID:24882011)

PMID:24882011

NCBI chr10:54,734,680...54,734,762
Ensembl chr10:54,734,678...54,734,766

Myd88

MYD88, innate immune signal transduction adaptor

acts_upstream_of_or_within

MGI:2147032|MGI:2385681 (PMID:10607756), (PMID:11067888), (PMID:12872135)

PMID:10607756 PMID:11067888 PMID:12872135

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

Nod1

nucleotide-binding oligomerization domain containing 1

acts_upstream_of_or_within

MGI:2429397|MGI:2674231 (PMID:18261938)

PMID:18261938

NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404

nucleotide-binding oligomerization domain containing 2

acts_upstream_of_or_within

MGI:1341839|MGI:2680581|MGI:3529594 (PMID:14560001), (PMID:15220916), (PMID:15692051), (PMID:18261938)

PMID:14560001 PMID:15220916 PMID:15692051 PMID:18261938

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

P2rx7

purinergic receptor P2X 7

acts_upstream_of_or_within

MGI:2386080|MGI:3606250 (PMID:11016935), (PMID:18490713)

PMID:11016935 PMID:18490713

NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619

Panx1

Pannexin 1

acts_upstream_of_or_within

(PMID:18490713)

PMID:18490713

NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774

Plcg2

phospholipase C, gamma 2

acts_upstream_of
involved_in

(MGI:5300086|PMID:22041900)
GO_REF:0000107

PMID:22041900

GO_REF:0000107 MGI:5300086

NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930

Pycard

PYD and CARD domain containing

acts_upstream_of_or_within

MGI:107700|MGI:2653833 (PMID:22002608)

PMID:22002608

NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955

Ripk2

receptor-interacting serine-threonine kinase 2

acts_upstream_of_or_within

MGI:2660793 (PMID:11894098), (PMID:18261938)

PMID:11894098 PMID:18261938

NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657

RT1 class Ib, locus M3, gene 1

involved_in

(PMID:19304799)

PMID:19304799

NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117

Rtn4

reticulon 4

involved_in

GO_REF:0000024
(MGI:4366092|PMID:19805174)

PMID:19805174

GO_REF:0000024 MGI:4366092

NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686

Sema7a

semaphorin 7A (John Milton Hagen blood group)

involved_in

(MGI:3710037|PMID:17377534)
GO_REF:0000033

PMID:17377534

GO_REF:0000033 MGI:3710037

NCBI chr 8:58,348,448...58,370,536
Ensembl chr 8:58,348,448...58,370,536

Sirt1

sirtuin 1

involved_in

(MGI:5319292|PMID:22315447)
GO_REF:0000107

PMID:22315447

GO_REF:0000107 MGI:5319292

NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260

Spon2

spondin 2

acts_upstream_of_or_within

MGI:3026870 (PMID:14691481)

PMID:14691481

NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996

Ticam1

TIR domain containing adaptor molecule 1

acts_upstream_of_or_within

MGI:108005|MGI:2679794|MGI:3029019 (PMID:12855817), (PMID:12872135)

PMID:12855817 PMID:12872135

NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147

Tirap

TIR domain containing adaptor protein

acts_upstream_of_or_within

MGI:3573942 (PMID:15690042)

PMID:15690042

NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432

Tlr2

toll-like receptor 2

acts_upstream_of_or_within

MGI:2178675|MGI:2674036 (PMID:10549626), (PMID:11067888), (PMID:15690042), (PMID:18261938)

PMID:10549626 PMID:11067888 PMID:15690042 PMID:18261938

NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630

Tlr3

toll-like receptor 3

acts_upstream_of_or_within

MGI:3690535 (PMID:12855817), (PMID:18261938)

PMID:12855817 PMID:18261938

NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545

Tlr4

toll-like receptor 4

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1857718|MGI:1860755|MGI:1860885 (PMID:10549626), (PMID:10607756), (PMID:10623794), (PMID:14691481), (PMID:15661922), (PMID:18261938), (PMID:21609717)

PMID:10549626 PMID:10607756 PMID:10623794 PMID:14691481 PMID:15661922 More...

GO_REF:0000107

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

Tlr7

toll-like receptor 7

acts_upstream_of_or_within

(PMID:18261938)

PMID:18261938

NCBI chr X:27,027,380...27,054,309
Ensembl chr X:27,027,425...27,054,754

Wnt5a

Wnt family member 5A

involved_in

(PMID:18174455)
GO_REF:0000107

PMID:18174455

GO_REF:0000107

NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234

positive regulation of mast cell activation involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Sphk2

sphingosine kinase 2

involved_in

(MGI:3703830|PMID:17346996)

PMID:17346996

MGI:3703830

NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391

positive regulation of mast cell cytokine production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fcer1a

Fc epsilon receptor Ia

acts_upstream_of_or_within

(PMID:9000133)

PMID:9000133

NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351

Fc epsilon receptor Ig

acts_upstream_of_or_within

MGI:2384004 (PMID:14764707)

PMID:14764707

NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443

Kit

KIT proto-oncogene receptor tyrosine kinase

involved_in

(PMID:20100931)

PMID:20100931

NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652

Nr4a3

nuclear receptor subfamily 4, group A, member 3

involved_in

GO_REF:0000024
(MGI:5586645|PMID:24586680)

PMID:24586680

GO_REF:0000024 MGI:5586645

NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733

Syk

spleen associated tyrosine kinase

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2384078 (PMID:9000133)

PMID:9000133

GO_REF:0000107

NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410

positive regulation of mast cell degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adora2b

adenosine A2B receptor

acts_upstream_of_or_within

(PMID:11454903)

PMID:11454903

NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772

Adora3

adenosine A3 receptor

acts_upstream_of_or_within

MGI:2155986 (PMID:12817016)

PMID:12817016

NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357

Crhr1

corticotropin releasing hormone receptor 1

RGD

PMID:18209484

RGD:5130941

NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481

Fcer1a

Fc epsilon receptor Ia

acts_upstream_of_or_within

(PMID:9000133)

PMID:9000133

NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351

Fc epsilon receptor Ig

acts_upstream_of_or_within

MGI:2384004 (PMID:14764707)

PMID:14764707

NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443

Fgr

FGR proto-oncogene, Src family tyrosine kinase

involved_in

GO_REF:0000024
(MGI:5294498|PMID:21746961)

PMID:21746961

GO_REF:0000024 MGI:5294498

NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326

Gab2

GRB2-associated binding protein 2

involved_in

(MGI:2137187|PMID:11449275)
GO_REF:0000024

PMID:11449275

GO_REF:0000024 MGI:2137187

NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031

Gata1

GATA binding protein 1

RGD

PMID:22390417

RGD:9587812

NCBI chr X:14,529,706...14,537,530
Ensembl chr X:14,529,702...14,537,530

Gata2

GATA binding protein 2

RGD

PMID:22390417

RGD:9587812

NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761

Il13

interleukin 13

acts_upstream_of_or_within

MGI:1931804|MGI:96556 (PMID:15944273)

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

interleukin 4

acts_upstream_of_or_within

MGI:1857195|MGI:96541 (PMID:15944273)

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

Il4r

interleukin 4 receptor

acts_upstream_of_or_within

MGI:1861951 (PMID:15944273)

NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980

Ms4a2

membrane spanning 4-domains A2

RGD

PMID:16177098

RGD:1578516

NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310

Nppc

natriuretic peptide C

involved_in

PMID:9663691

UniProt

PMID:9663691

RGD:13461752

NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251

phospholipase D2

RGD

NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808

Sphk2

sphingosine kinase 2

involved_in

(MGI:3703830|PMID:17346996)

PMID:17346996

MGI:3703830

NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391

Stxbp1

syntaxin binding protein 1

RGD

PMID:23487749

RGD:12904029

NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369

Stxbp2

syntaxin binding protein 2

RGD
TreeGrafter
GO_Central
Ensembl

RGD

PMID:23487749

RGD:12904029

NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458

Syk

spleen associated tyrosine kinase

acts_upstream_of_or_within
involved_in

IMP
ISO
IEA
IBA

MGI:2384078 (PMID:9000133)
GO_REF:0000118
GO_REF:0000033
GO_REF:0000107

PMID:9000133 PMID:16861349

GO_REF:0000033 GO_REF:0000107 GO_REF:0000118, RGD:2299903

NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410

positive regulation of MDA-5 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ankrd17

ankyrin repeat domain 17

involved_in

(PMID:22328336)

PMID:22328336

NCBI chr14:17,723,239...17,861,841
Ensembl chr14:17,721,932...17,862,617

Ddx60

DEXD/H-box helicase 60

involved_in

(PMID:21791617)

PMID:21791617

NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526

Dhx58

DEXH-box helicase 58

involved_in

(MGI:4421606|PMID:20080593)

PMID:20080593

MGI:4421606

NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525

Usp17la2

ubiquitin specific peptidase 17-like a2

involved_in

(PMID:20368735)

PMID:20368735

NCBI chr 1:159,151,417...159,155,192
Ensembl chr 1:159,151,432...159,155,192

positive regulation of memory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd46

CD46 molecule

involved_in

(PMID:12540904)

PMID:12540904

NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445

Il23a

interleukin 23 subunit alpha

involved_in

(MGI:3027369|PMID:14688363)

PMID:14688363

MGI:3027369

NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923

Pck1

phosphoenolpyruvate carboxykinase 1

involved_in

GO_REF:0000024
(MGI:6119963|PMID:29230018)

PMID:29230018

GO_REF:0000024 MGI:6119963

NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191

RT1-Da

RT1 class II, locus Da

involved_in

(PMID:27591323)

PMID:27591323

NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455

RT1-Db1

RT1 class II, locus Db1

involved_in

(PMID:27591323)

PMID:27591323

NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258

TNF superfamily member 4

involved_in

(MGI:3806904|PMID:18713990)

PMID:18713990

MGI:3806904

NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788

positive regulation of microglial cell mediated cytotoxicity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Itgam

integrin subunit alpha M

involved_in

(MGI:3812233|PMID:18685038)

PMID:18685038

MGI:3812233

NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503

Spi1

Spi-1 proto-oncogene

involved_in

(MGI:6093262|PMID:28628103)

PMID:28628103

MGI:6093262

NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393

Stap1

signal transducing adaptor family member 1

involved_in

(MGI:3831067|PMID:19100238)

PMID:19100238

MGI:3831067

NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245

Tyrobp

transmembrane immune signaling adaptor Tyrobp

involved_in

(MGI:3812233|PMID:18685038)
GO_REF:0000033

PMID:18685038

GO_REF:0000033 MGI:3812233

NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848

positive regulation of myeloid dendritic cell cytokine production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Camk4

calcium/calmodulin-dependent protein kinase IV

NOT|involved_in

(PMID:17909078)

PMID:17909078

NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487

Ddx1

DEAD-box helicase 1

involved_in

(MGI:5050760|PMID:21703541)

NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365

Ddx21

DExD-box helicase 21

involved_in

(MGI:5050760|PMID:21703541)

NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543

Dhx36

DEAH-box helicase 36

involved_in

(MGI:5050760|PMID:21703541)

NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572

Mavs

mitochondrial antiviral signaling protein

involved_in

GO_REF:0000024
(MGI:5050760|PMID:21703541)

GO_REF:0000024 MGI:5050760

NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094

Rig1

RNA sensor RIG-1

involved_in

(MGI:5050760|PMID:21703541)

NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819

Ticam1

TIR domain containing adaptor molecule 1

involved_in

(MGI:5050760|PMID:21703541)

NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147

Ticam2

TIR domain containing adaptor molecule 2

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462

positive regulation of myeloid leukocyte cytokine production involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Mif

macrophage migration inhibitory factor

involved_in

(MGI:2156302|PMID:11756671)

PMID:11756671

MGI:2156302

NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504

positive regulation of natural killer cell cytokine production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD160 molecule

involved_in

(PMID:17307798)

PMID:17307798

NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834

CD226 molecule

involved_in
acts_upstream_of_or_within

GO_REF:0000033
MGI:4454325 (PMID:24658051)

PMID:24658051

GO_REF:0000033

NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051

Clnk

cytokine-dependent hematopoietic cell linker

involved_in

(MGI:3774350|PMID:16439675)

PMID:16439675

MGI:3774350

NCBI chr14:71,923,894...72,101,180
Ensembl chr14:71,873,105...72,101,208

Gimap5

GTPase, IMAP family member 5

RGD

PMID:15100275

RGD:2303778

NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086

Il21

interleukin 21

acts_upstream_of_or_within

(PMID:14764669)

PMID:14764669

NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996

RT1 class Ia, locus A2

involved_in

(PMID:30134159)

PMID:30134159

NCBI chr20:4,870,939...4,910,183

RT1-CE5

RT1 class I, locus CE5

involved_in

(PMID:27455421)

PMID:27455421

NCBI chr20:3,403,418...3,479,476

RT1 class Ib, locus M3, gene 1

involved_in

(PMID:16366734), (PMID:19304799), (PMID:23184984)

PMID:16366734 PMID:19304799 PMID:23184984

NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117

positive regulation of natural killer cell degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ap1g1

adaptor related protein complex 1 subunit gamma 1

involved_in

(PMID:23632890)

NCBI chr19:37,744,633...37,831,134
Ensembl chr19:37,744,633...37,829,167

CD160 molecule

involved_in

(PMID:19109136)

PMID:19109136

NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834

Klrc2

killer cell lectin like receptor C2

involved_in

(PMID:21825173)

PMID:21825173

NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843

Lamp1

lysosomal-associated membrane protein 1

involved_in

(PMID:23632890)
GO_REF:0000107

GO_REF:0000107

NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883

RT1-CE5

RT1 class I, locus CE5

involved_in

(PMID:27455421)

PMID:27455421

NCBI chr20:3,403,418...3,479,476

positive regulation of natural killer cell mediated cytotoxicity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ap1g1

adaptor related protein complex 1 subunit gamma 1

involved_in

(PMID:23632890)

NCBI chr19:37,744,633...37,831,134
Ensembl chr19:37,744,633...37,829,167

Cadm1

cell adhesion molecule 1

involved_in

(PMID:15811952)
(MGI:3689781|PMID:15811952)
GO_REF:0000024

RGD
HGNC

GO_REF:0000024 MGI:3689781

NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833

CD160 molecule

involved_in

(PMID:12486241), (PMID:17307798)

PMID:12486241 PMID:17307798

NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834

CD226 molecule

involved_in

(PMID:16304049)

NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051

Crtam

cytotoxic and regulatory T cell molecule

involved_in

(PMID:15811952)
(MGI:3689781|PMID:15811952)

MGI:3689781

NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343

Gimap5

GTPase, IMAP family member 5

RGD

PMID:15100275

RGD:2303778

NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086

Il12a

interleukin 12A

involved_in

(PMID:2204066)

PMID:2204066

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

Il18rap

interleukin 18 receptor accessory protein

acts_upstream_of_or_within

MGI:3579137 (PMID:15843532)

PMID:14764669 PMID:18005035

PMID:15843532

NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959

Il21

interleukin 21

involved_in
acts_upstream_of_or_within

ISO
IBA
IEA

(PMID:18005035)
(PMID:14764669)
GO_REF:0000033
GO_REF:0000107

RGD
GO_Central
Ensembl

GO_REF:0000033 GO_REF:0000107

NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996

Klrc1

killer cell lectin like receptor C1

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425

Klrc2

killer cell lectin like receptor C2

involved_in

(PMID:9754572)
GO_REF:0000033

PMID:9754572

GO_REF:0000033

NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843

Klrc3

killer cell lectin like receptor C3

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:163,105,081...163,112,737
Ensembl chr 4:163,106,024...163,112,336

Klrd1

killer cell lectin like receptor D1

involved_in

ISO
IBA
IEA

(PMID:9754572)
GO_REF:0000033
GO_REF:0000107

RGD
GO_Central
Ensembl

PMID:9754572

GO_REF:0000033 GO_REF:0000107

NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518

Klre1

killer cell lectin like receptor E1

involved_in

(PMID:15294961)
GO_REF:0000033

PMID:15294961

GO_REF:0000033

NCBI chr 4:163,033,581...163,041,641
Ensembl chr 4:163,033,563...163,041,638

Klri1

killer cell lectin-like receptor family I member 1

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr 4:163,183,675...163,218,903
Ensembl chr 4:163,183,669...163,218,870

Klri2

killer cell lectin-like receptor family I member 2

involved_in

GO_REF:0000033

UniProt
RGD
TreeGrafter
GO_Central
InterPro
Ensembl

GO_REF:0000033

NCBI chr 4:163,252,844...163,261,484
Ensembl chr 4:163,252,844...163,261,484

Klrk1

killer cell lectin like receptor K1

involved_in
acts_upstream_of_or_within

ISS
ISO
IEA
IBA

GO_REF:0000024
(PMID:12645935)
GO_REF:0000118
GO_REF:0000033
GO_REF:0000002
(MGI:3054301|PMID:15294961)
GO_REF:0000107
(PMID:15294961)

PMID:12645935 PMID:15294961

GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:3054301

NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459

Lag3

lymphocyte activating 3

acts_upstream_of_or_within

MGI:2176269 (PMID:8602528)

PMID:8602528

NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404

Lamp1

lysosomal-associated membrane protein 1

involved_in

(PMID:23632890)

NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883

Ly49s3

Ly-49 stimulatory receptor 3

RGD
GO_Central
TreeGrafter
Ensembl
InterPro

RGD

PMID:12077224

RGD:633264

Ensembl chr 4:164,122,072...164,341,692

Ncr3

natural cytotoxicity triggering receptor 3

involved_in

ISO
IBA
IEA

(PMID:16304049)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
GO_REF:0000002

GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118

NCBI chr20:3,637,242...3,643,748
Ensembl chr20:3,638,240...3,643,799

nectin cell adhesion molecule 2

involved_in

(PMID:16304049)

NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360

PVR cell adhesion molecule

involved_in

(PMID:16304049)

NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715

Raet1e

retinoic acid early transcript 1E

involved_in

(PMID:18544572)

PMID:18544572

NCBI chr 1:1,662,665...1,664,609
Ensembl chr 1:1,807,644...1,812,755

Raet1l

retinoic acid early transcript 1L

RGD

PMID:20306467

RGD:9685184

NCBI chr 1:1,979,433...1,984,410
Ensembl chr 1:1,979,443...1,984,410

Raet1ll1

retinoic acid early transcript 1L like 1

RGD

PMID:20306467

RGD:9685184

NCBI chr 1:1,397,219...1,437,802
Ensembl chr 1:1,397,230...1,402,656

Rasgrp1

RAS guanyl releasing protein 1

involved_in

(PMID:19933860)
GO_REF:0000107

PMID:19933860

GO_REF:0000107

NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056

RT1 class Ia, locus A2

involved_in

(PMID:23335510)

PMID:23335510

NCBI chr20:4,870,939...4,910,183

RT1 class Ib, locus M3, gene 1

acts_upstream_of_or_within

MGI:3701255 (PMID:16476767)

PMID:16476767

NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117

Sh2d1a

SH2 domain containing 1A

acts_upstream_of_or_within

MGI:1349420|MGI:3575311|MGI:3622649 (PMID:16127454), (PMID:19648922)

PMID:16127454 PMID:19648922

NCBI chr X:121,373,693...121,401,923

Sh2d1b2

SH2 domain containing 1B2

acts_upstream_of_or_within

MGI:1328352|MGI:1349420|MGI:98923 (PMID:19648922), (PMID:20962259)

PMID:19648922 PMID:20962259

NCBI chr13:82,437,418...82,461,511
Ensembl chr13:82,437,428...82,461,509

Slamf6

SLAM family member 6

involved_in

(PMID:16920955)

PMID:16920955

NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300

Stat5a

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

MGI:1857249 (PMID:9841920)

PMID:9841920

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

Stat5b

signal transducer and activator of transcription 5B

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2181592 (PMID:9841920)

PMID:9841920

GO_REF:0000107

NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668

Vav1

vav guanine nucleotide exchange factor 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1349420|MGI:3622649 (PMID:20962259)

PMID:20962259

GO_REF:0000107

NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937

positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD226 molecule

involved_in

(PMID:12913096)
GO_REF:0000033

GO_REF:0000033

NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051

Crtam

cytotoxic and regulatory T cell molecule

involved_in

(PMID:15811952)
GO_REF:0000033
(MGI:3689781|PMID:15811952)

GO_REF:0000033 MGI:3689781

NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343

Il12a

interleukin 12A

involved_in

(PMID:7903063)
GO_REF:0000107

PMID:7903063

GO_REF:0000107

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

Il12b

interleukin 12B

involved_in

(PMID:7903063)

PMID:7903063

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

Klrk1

killer cell lectin like receptor K1

RGD

PMID:16323246

RGD:9685180

NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459

nectin cell adhesion molecule 2

involved_in

(PMID:12913096)
GO_REF:0000033

GO_REF:0000033

NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360

PVR cell adhesion molecule

involved_in

(PMID:12913096)

NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715

Raet1ll1

retinoic acid early transcript 1L like 1

RGD

PMID:16323246

RGD:9685180

NCBI chr 1:1,397,219...1,437,802
Ensembl chr 1:1,397,230...1,402,656

positive regulation of natural killer cell mediated immune response to tumor cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD160 molecule

involved_in

(MGI:5644003|PMID:25711213)

PMID:25711213

MGI:5644003

NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834

positive regulation of natural killer cell mediated immunity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dpp4

dipeptidylpeptidase 4

RGD

PMID:19327106

RGD:41408336

NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901

Rasgrp4

RAS guanyl releasing protein 4

involved_in

ISS

GO_REF:0000024

UniProt

GO_REF:0000024

NCBI chr 1:84,433,033...84,452,841
Ensembl chr 1:84,433,064...84,451,896

RT1 class Ia, locus A2

involved_in

(PMID:9754572)

PMID:9754572

NCBI chr20:4,870,939...4,910,183

positive regulation of neutrophil degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd177

CD177 molecule

involved_in

UniProtKB:P05107|UniProtKB:P11215 (PMID:21193407)
GO_REF:0000033

PMID:21193407

GO_REF:0000033

NCBI chr 1:80,340,034...80,360,599
Ensembl chr 1:80,340,034...80,360,621

Cd177l1

CD177 molecule like 1

involved_in

GO_REF:0000118

GO_REF:0000118

NCBI chr 1:80,288,192...80,293,773
Ensembl chr 1:80,288,194...80,293,484

Cd177l2

CD177 molecule like 2

involved_in

IEA
IBA

GO_REF:0000118
GO_REF:0000033

TreeGrafter
GO_Central

GO_REF:0000033 GO_REF:0000118

NCBI chr 1:80,323,188...80,328,311
Ensembl chr 1:80,323,863...80,328,311

Itgam

integrin subunit alpha M

involved_in

UniProtKB:P05107|UniProtKB:Q8N6Q3 (PMID:21193407)

PMID:21193407

NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503

Itgb2

integrin subunit beta 2

involved_in

UniProtKB:P11215|UniProtKB:Q8N6Q3 (PMID:21193407)

PMID:21193407

NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600

Lypd10

Ly6/PLAUR domain containing 10

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:80,273,019...80,278,238
Ensembl chr 1:80,273,019...80,278,219

Lypd10l1

Ly6/PLAUR domain containing 10 like 1

involved_in

GO_REF:0000118

GO_REF:0000118

NCBI chr 1:80,308,234...80,312,967
Ensembl chr 1:80,308,643...80,312,222

Ptafr

platelet-activating factor receptor

RGD

PMID:2829894

RGD:10041060

NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251

positive regulation of neutrophil mediated killing of fungus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Arg1

arginase 1

involved_in

(PMID:15546957)
GO_REF:0000107

PMID:15546957

GO_REF:0000107

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

Cxcl1

C-X-C motif chemokine ligand 1

involved_in

GO_REF:0000107
(MGI:5586806|PMID:10725737)

PMID:10725737

GO_REF:0000107 MGI:5586806

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

Pomc

proopiomelanocortin

involved_in

(PMID:10670585)

PMID:10670585

NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664

positive regulation of neutrophil mediated killing of gram-negative bacterium

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

F2rl1

F2R like trypsin receptor 1

involved_in

(PMID:21501162)

PMID:21501162

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

positive regulation of opsonization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Colec10

collectin subfamily member 10

involved_in

(PMID:24174618)

PMID:24174618

NCBI chr 7:85,744,895...85,806,368
Ensembl chr 7:85,744,895...85,805,675

Colec11

collectin sub-family member 11

involved_in

(PMID:24174618)

PMID:24174618

NCBI chr 6:45,223,974...45,256,640
Ensembl chr 6:45,223,980...45,271,145

Fcnb

ficolin B

involved_in

(PMID:16116205)

PMID:16116205

NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151

Mbl2

mannose binding lectin 2

involved_in

(PMID:22966085)

PMID:22966085

NCBI chr 1:228,016,439...228,024,736

Myo18a

myosin XVIIIa

involved_in

(PMID:21123169)
GO_REF:0000107
(MGI:5810257|PMID:21123169)

PMID:21123169

GO_REF:0000107 MGI:5810257

NCBI chr10:62,654,218...62,755,465
Ensembl chr10:62,654,281...62,755,468

Pla2g5

phospholipase A2, group V

involved_in

GO_REF:0000024
(MGI:3841317|PMID:19342668)

PMID:19342668

GO_REF:0000024 MGI:3841317

NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658

positive regulation of peripheral T cell tolerance induction

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Foxp3

forkhead box P3

acts_upstream_of_or_within

MGI:2654936 (PMID:16532000)

PMID:16532000

NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838

positive regulation of plasma cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Il10

interleukin 10

acts_upstream_of

UniProtKB:P60568 (PMID:22962438)

PMID:22962438

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

Il2

interleukin 2

acts_upstream_of

UniProtKB:P22301 (PMID:22962438)

PMID:22962438

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

Xbp1

X-box binding protein 1

involved_in

ISO
IEA
ISS

(PMID:11460154)
GO_REF:0000107
GO_REF:0000024

RGD
Ensembl
UniProt

PMID:11460154

GO_REF:0000024 GO_REF:0000107

NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693

positive regulation of respiratory burst involved in inflammatory response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Lbp

lipopolysaccharide binding protein

involved_in

(MGI:1097829|PMID:9338787)
GO_REF:0000107

PMID:9338787

GO_REF:0000107 MGI:1097829

NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586

Rps19

ribosomal protein S19

involved_in

(PMID:15750715)

PMID:8766544 PMID:11046035

PMID:15750715

NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508

positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd81

Cd81 molecule

involved_in

ISS
ISO
IEA

GO_REF:0000024
(PMID:8766544)
(MGI:1926561|PMID:11046035)
GO_REF:0000107

UniProt
RGD
Ensembl

GO_REF:0000024 GO_REF:0000107 MGI:1926561

NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660

Lgals9

galectin 9

involved_in

(PMID:16116184)

PMID:16116184

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

RT1-DMb

RT1 class II, locus DMb

involved_in

(PMID:8139689)

PMID:8139689

NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340

positive regulation of T cell cytokine production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

B2m

beta-2 microglobulin

involved_in

(PMID:24643698)
GO_REF:0000107

PMID:24643698

GO_REF:0000107

NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766

Cd55

CD55 molecule (Cromer blood group)

involved_in

(PMID:16818763)

PMID:16818763

NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831

Fzd5

frizzled class receptor 5

involved_in

(PMID:16601243)
GO_REF:0000107

PMID:16601243

GO_REF:0000107

NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457

Malt1

MALT1 paracaspase

involved_in

(PMID:15125833)

NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260

Map3k7

mitogen activated protein kinase kinase kinase 7

involved_in

(PMID:15125833)

NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597

RT1-CE16

RT1 class I, locus CE16

involved_in

(PMID:24643698)

PMID:24643698

NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563

Sash3

SAM and SH3 domain containing 3

acts_upstream_of_or_within

MGI:3716944 (PMID:16227612)

PMID:16227612

NCBI chr X:127,326,815...127,341,521
Ensembl chr X:127,326,859...127,341,519

TNF superfamily member 4

involved_in

(MGI:4942267|PMID:9670042), (MGI:4943387|PMID:18354165)

PMID:9670042 PMID:18354165

MGI:4942267 MGI:4943387

NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788

Traf2

Tnf receptor-associated factor 2

involved_in

(PMID:15125833)

NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538

Traf6

TNF receptor associated factor 6

involved_in

(PMID:15125833)
GO_REF:0000107

GO_REF:0000107

NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507

X-C motif chemokine ligand 1

involved_in

(MGI:85636|PMID:9029087)

PMID:9029087

MGI:85636

NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329

positive regulation of T cell mediated cytotoxicity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AABR07000137.1

involved_in

GO_REF:0000033

GO_REF:0000033

Ensembl chr 1:1,307,185...1,308,310

involved_in

GO_REF:0000033

GO_REF:0000033

involved_in

GO_REF:0000033

GO_REF:0000033

Ensembl chr 1:39,668,472...39,670,153

AABR07044308.1

involved_in

GO_REF:0000118

GO_REF:0000118

Ensembl chr20:1,789,779...1,793,115

AABR07044308.2

involved_in

GO_REF:0000118

GO_REF:0000118

Ensembl chr20:1,768,641...1,772,357

AABR07044362.1

involved_in

GO_REF:0000118

GO_REF:0000118

Ensembl chr20:2,630,622...2,634,751

AABR07044383.1

involved_in

GO_REF:0000118

GO_REF:0000118

Ensembl chr20:3,403,777...3,436,874

AABR07044397.1

involved_in

GO_REF:0000118

GO_REF:0000118

Ensembl chr20:2,496,605...2,497,428

involved_in

GO_REF:0000118

GO_REF:0000118

beta-2 microglobulin

acts_upstream_of_or_within

(PMID:16299293)

TreeGrafter
RGD
GO_Central

PMID:16299293

NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766

Cd1d1

CD1d1 molecule

involved_in
acts_upstream_of_or_within

IEA
ISO
IBA

GO_REF:0000118
(PMID:10201995)
GO_REF:0000033

PMID:10201995

GO_REF:0000033 GO_REF:0000118

NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089

Cyrib

CYFIP related Rac1 interactor B

involved_in

(MGI:5432330|PMID:22522492)

PMID:22522492

MGI:5432330

NCBI chr 7:95,633,876...95,760,588
Ensembl chr 7:95,633,876...95,697,686

ENSRNOG00000064836

involved_in

GO_REF:0000118

GO_REF:0000118

Ensembl chr20:2,606,621...2,618,153

ENSRNOG00000069480

involved_in

GO_REF:0000118

GO_REF:0000118

Ensembl chr20:3,310,825...3,421,372

Fadd

Fas associated via death domain

involved_in

GO_REF:0000024
(MGI:5291865|PMID:21876153)

PMID:21876153

GO_REF:0000024 MGI:5291865

NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653

H2-M10.6l

histocompatibility 2, M region locus 10.6 like

involved_in

GO_REF:0000118

GO_REF:0000118

NCBI chr20:1,958,270...1,965,247
Ensembl chr20:1,925,049...1,966,105

H60al

histocompatibility 60a like

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:1,382,896...1,386,846

Hfe

homeostatic iron regulator

involved_in

IEA
IBA

GO_REF:0000118
GO_REF:0000033

TreeGrafter
GO_Central

GO_REF:0000033 GO_REF:0000118

NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502

Hspa1b

heat shock protein family A (Hsp70) member 1B

prevention of heat shock-induced resistance to CTL-mediated killing

RGD

PMID:10679071

RGD:1298959

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

Hspa8

heat shock protein family A (Hsp70) member 8

RGD

PMID:8871636

RGD:10059395

NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259

Il12a

interleukin 12A

involved_in

(PMID:1674604), (PMID:2204066)
GO_REF:0000107

PMID:1674604 PMID:2204066

GO_REF:0000107

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

Il12b

interleukin 12B

involved_in

(MGI:3027369|PMID:14688363)

PMID:14688363

MGI:3027369

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

Il23a

interleukin 23 subunit alpha

involved_in

(MGI:3027369|PMID:14688363)

PMID:14688363

MGI:3027369

NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923

Micb

MHC class I polypeptide-related sequence B

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000118

GO_Central
TreeGrafter

GO_REF:0000033 GO_REF:0000118

NCBI chr 1:78,495,779...78,513,030
Ensembl chr 1:78,495,779...78,512,827

Mill1

MHC I like leukocyte 1

involved_in

IBA
IEA

GO_REF:0000033
GO_REF:0000118

GO_Central
TreeGrafter

GO_REF:0000033 GO_REF:0000118

NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930

Mr1

major histocompatibility complex, class I-related

involved_in

GO_REF:0000118

GO_REF:0000118

NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970

P2rx7

purinergic receptor P2X 7

acts_upstream_of_or_within

MGI:3042190 (PMID:14761980)

PMID:14761980

NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619

protein tyrosine phosphatase, receptor type, C

acts_upstream_of_or_within

(PMID:6233370)

PMID:6233370

NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692

Raet1l

retinoic acid early transcript 1L

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr 1:1,979,433...1,984,410
Ensembl chr 1:1,979,443...1,984,410

RT1-A

RT1 class I, locus A

involved_in

GO_REF:0000033

GO_REF:0000033

RT1-A1

RT1 class Ia, locus A1

involved_in

IDA
IBA

GO_REF:0000033

PMID:11773898

GO_REF:0000033, RGD:2313503

NCBI chr20:4,905,309...4,914,593

RT1 class Ia, locus A2

involved_in
acts_upstream_of_or_within

(PMID:20195504), (PMID:25631937)
(PMID:1538753)
GO_REF:0000033

PMID:1538753 PMID:20195504 PMID:25631937

GO_REF:0000033

NCBI chr20:4,870,939...4,910,183

RT1-CE1

RT1 class I, locus1

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr20:3,555,779...3,559,487
Ensembl chr20:3,555,782...3,559,486

RT1-CE10

RT1 class I, locus CE10

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr20:3,377,284...3,380,301

RT1-CE11

RT1 class I, locus CE11

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr20:3,355,393...3,358,520
Ensembl chr20:3,350,937...3,380,362

RT1-CE14

RT1 class I, locus CE14

involved_in

GO_REF:0000118

GO_REF:0000118

NCBI chr20:3,296,654...3,300,795
Ensembl chr20:3,297,196...3,305,134

RT1-CE16

RT1 class I, locus CE16

involved_in

(PMID:22031944), (PMID:2420472), (PMID:25631937), (PMID:8805302)

PMID:2420472 PMID:8805302 PMID:22031944 PMID:25631937

NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563

RT1-CE2

RT1 class I, locus CE2

involved_in

GO_REF:0000118

GO_REF:0000118

NCBI chr20:3,538,452...3,541,841
Ensembl chr20:3,537,809...3,541,790

RT1-CE3

RT1 class I, locus CE3

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr20:3,516,647...3,520,938
Ensembl chr20:2,623,953...2,692,081

RT1-CE5

RT1 class I, locus CE5

involved_in

(PMID:23851683)
GO_REF:0000033

PMID:23851683

GO_REF:0000033

NCBI chr20:3,403,418...3,479,476

RT1-CE7

RT1 class I, locus CE7

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr20:3,434,205...3,437,152

RT1-Da

RT1 class II, locus Da

involved_in

(PMID:29884618)

PMID:29884618

NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455

RT1-Db1

RT1 class II, locus Db1

involved_in

(PMID:29884618)

PMID:29884618

NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258

RT1-M1-2

RT1 class I, locus M1, gene 2

involved_in

GO_REF:0000118

GO_REF:0000118

NCBI chr20:1,909,506...1,913,423
Ensembl chr20:1,910,656...1,917,936

RT1-M1-4

RT1 class I, locus M1, gene 4

involved_in

GO_REF:0000118

GO_REF:0000118

NCBI chr20:1,891,365...1,893,585
Ensembl chr20:1,889,164...1,893,815

RT1-M1-5

RT1 class I, M1, gene 5

involved_in

GO_REF:0000118

GO_REF:0000118

NCBI chr20:1,858,608...1,860,708
Ensembl chr20:1,811,604...1,860,708

RT1-M10-1

RT1 class I, locus M10, gene 1

involved_in

GO_REF:0000118

GO_REF:0000118

NCBI chr20:1,986,817...1,988,908
Ensembl chr20:1,986,788...2,020,117

RT1-M2

RT1 class Ib, locus M2

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr20:978,918...981,510
Ensembl chr20:978,935...981,723

RT1 class Ib, locus M3, gene 1

involved_in
acts_upstream_of_or_within

GO_REF:0000033
MGI:3701255 (PMID:16299293), (PMID:16461341), (PMID:16476767), (PMID:8464890)

PMID:8464890 PMID:16299293 PMID:16461341 PMID:16476767

GO_REF:0000033

NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117

RT1-M5

RT1 class Ib, locus M5

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr20:1,546,496...1,548,948
Ensembl chr20:1,546,511...1,548,775

RT1-M6-2

RT1 class I, locus M6, gene 2

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr20:1,583,267...1,587,099
Ensembl chr20:1,583,299...1,586,215

RT1-N1

RT1 class Ib, locus N1

involved_in

GO_REF:0000033

GO_REF:0000033

RT1-N2

RT1 class Ib, locus N2

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr20:2,641,157...2,645,439
Ensembl chr20:2,641,202...2,644,900

RT1-N3

RT1 class Ib, locus N3

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr20:2,659,132...2,665,536
Ensembl chr20:2,661,584...2,665,530

RT1-O1

RT1 class Ib, locus O1

involved_in

GO_REF:0000118

GO_REF:0000118

NCBI chr20:2,655,116...2,657,520
Ensembl chr20:2,655,116...2,657,520

RT1-O1l1

RT1 class Ib, locus O1 like 1

involved_in

IEA
IBA

GO_REF:0000118
GO_REF:0000033

TreeGrafter
GO_Central

GO_REF:0000033 GO_REF:0000118

NCBI chr20:2,624,073...2,658,023
Ensembl chr20:2,623,953...2,692,081

RT1-S2

RT1 class Ib, locus S2

involved_in

GO_REF:0000118

GO_REF:0000118

NCBI chr20:2,650,233...2,651,654
Ensembl chr20:2,649,964...2,652,027

RT1-S3

RT1 class Ib, locus S3

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411

RT1-T24-1

RT1 class I, locus T24, gene 1

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr20:2,761,495...2,774,871
Ensembl chr20:2,718,279...2,776,154

RT1-T24-3

RT1 class I, locus T24, gene 3

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr20:2,718,210...2,730,604
Ensembl chr20:2,718,279...2,776,154

RT1-T24-4

RT1 class I, locus T24, gene 4

involved_in

GO_REF:0000033

GO_REF:0000033

NCBI chr20:2,684,515...2,747,878
Ensembl chr20:2,684,515...2,692,511

Stx7

syntaxin 7

involved_in

(PMID:21438968)
GO_REF:0000107

PMID:21438968

GO_REF:0000107

NCBI chr 1:21,197,075...21,237,320
Ensembl chr 1:21,197,075...21,237,279

Tap2

transporter 2, ATP binding cassette subfamily B member

acts_upstream_of_or_within
involved_in

IDA
ISO
IEA

PMID:1758495
(PMID:1538753), (PMID:16299293)
GO_REF:0000107

PMID:1538753 PMID:16299293 PMID:1758495

GO_REF:0000107, RGD:1299069

NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407

X-C motif chemokine ligand 1

involved_in

(PMID:18832695)

PMID:18832695

NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329

positive regulation of T cell mediated cytotoxicity directed against tumor cell target

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Mr1

major histocompatibility complex, class I-related

involved_in

(PMID:31959982)
GO_REF:0000107

PMID:31959982

GO_REF:0000107

NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970

Slc22a13

solute carrier family 22 member 13

involved_in

(PMID:19282870)

PMID:19282870

NCBI chr 8:118,922,367...118,934,020
Ensembl chr 8:118,922,367...118,953,635

positive regulation of T cell mediated immune response to tumor cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd24

CD24 molecule

acts_upstream_of_or_within

(PMID:7774619)

PMID:7774619

NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662

Fbxo38

F-box protein 38

involved_in

(PMID:30487606)

PMID:30487606

NCBI chr18:55,956,950...56,004,013
Ensembl chr18:55,956,959...56,003,961

Hspd1

heat shock protein family D (Hsp60) member 1

involved_in

(PMID:10663613)

PMID:10663613

NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662

RT1-Db1

RT1 class II, locus Db1

involved_in

(PMID:30282837)

PMID:30282837

NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258

positive regulation of T cell mediated immunity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

protein tyrosine phosphatase, receptor type, C

acts_upstream_of_or_within

MGI:2181288 (PMID:6233370), (PMID:8566034)

PMID:6233370 PMID:8566034

NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692

Zbtb1

zinc finger and BTB domain containing 1

involved_in

(MGI:5446979|PMID:22753936)

PMID:22753936

MGI:5446979

NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996

positive regulation of T-helper 1 cell cytokine production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Arid5a

AT-rich interaction domain 5A

involved_in

(MGI:5887181|PMID:27671645)

PMID:27671645

MGI:5887181

NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597

Il18

interleukin 18

involved_in

IEA
ISS
ISO

GO_REF:0000107
GO_REF:0000024
(PMID:10653850)

Ensembl
UniProt
RGD

GO_REF:0000024 GO_REF:0000107

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

Il18r1

interleukin 18 receptor 1

involved_in

(PMID:10653850)

NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715

Il1b

interleukin 1 beta

involved_in

(PMID:10653850)
GO_REF:0000024

GO_REF:0000024

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

Il1r1

interleukin 1 receptor type 1

involved_in

(PMID:10653850)
GO_REF:0000024

GO_REF:0000024

NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937

Slamf1

signaling lymphocytic activation molecule family member 1

involved_in

(MGI:5700493|PMID:9126961)

PMID:9126961

MGI:5700493

NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497

Tbx21

T-box transcription factor 21

involved_in

(MGI:1354779|PMID:10761931)

PMID:10761931

MGI:1354779

NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831

X-C motif chemokine ligand 1

involved_in

GO_REF:0000107
(MGI:5009207|PMID:9973465)

UniProt
RGD
Ensembl
TreeGrafter

PMID:9973465

GO_REF:0000107 MGI:5009207

NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329

positive regulation of T-helper 1 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Anxa1

annexin A1

involved_in

ISS
ISO
IEA

GO_REF:0000024
(PMID:17008549)
GO_REF:0000107
GO_REF:0000118

PMID:17008549

GO_REF:0000024 GO_REF:0000107 GO_REF:0000118

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

Ccl19

C-C motif chemokine ligand 19

involved_in

(MGI:3576832|PMID:15845453)

PMID:15845453

MGI:3576832

NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308

Hlx

H2.0-like homeobox

acts_upstream_of_or_within

MGI:105367|MGI:2182089 (PMID:16424184)

PMID:16424184

NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750

Ripk2

receptor-interacting serine-threonine kinase 2

acts_upstream_of_or_within

MGI:2446070 (PMID:11894097)

PMID:11894097

NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657

Socs5

suppressor of cytokine signaling 5

involved_in

(MGI:3687909|PMID:12242343)

PMID:12242343

MGI:3687909

NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834

positive regulation of T-helper 17 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Malt1

MALT1 paracaspase

involved_in

(MGI:6142401|PMID:25282160)

PMID:25282160

MGI:6142401

NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260

Mir326

microRNA 326

acts_upstream_of_or_within

(PMID:19838199)

PMID:19838199

NCBI chr 1:153,854,029...153,854,123
Ensembl chr 1:153,854,029...153,854,123

Nfkbid

NFKB inhibitor delta

involved_in

(MGI:6142401|PMID:25282160)

PMID:25282160

MGI:6142401

NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447

Nfkbiz

NFKB inhibitor zeta

involved_in

(MGI:6142401|PMID:25282160)

PMID:25282160

MGI:6142401

NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723

NLR family, pyrin domain containing 3

involved_in

(MGI:5689221|PMID:26098997)

PMID:26098997

MGI:5689221

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

positive regulation of T-helper 17 cell lineage commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Brd2

bromodomain containing 2

involved_in

GO_REF:0000024
(MGI:6106706|PMID:28262505)
(PMID:28262505)

PMID:28262505

GO_REF:0000024 MGI:6106706

NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388

Brd4

bromodomain containing 4

involved_in

(MGI:6106706|PMID:28262505)

PMID:28262505

MGI:6106706

NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539

Ep300

E1A binding protein p300

involved_in

(PMID:28262505)

PMID:28262505

NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088

Il23a

interleukin 23 subunit alpha

involved_in

(MGI:3851279|PMID:19501566)
GO_REF:0000033

PMID:19501566

GO_REF:0000033 MGI:3851279

NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923

Opa1

OPA1, mitochondrial dynamin like GTPase

involved_in

ISS

GO_REF:0000024

UniProt

GO_REF:0000024

NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109

positive regulation of T-helper 2 cell cytokine production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd81

Cd81 molecule

involved_in

GO_REF:0000024
GO_REF:0000107
(MGI:1926561|PMID:11046035)
(PMID:8766544)

PMID:8766544 PMID:11046035

GO_REF:0000024 GO_REF:0000107 MGI:1926561

NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660

Dennd1b

DENN domain containing 1B

involved_in

(PMID:26774822)
(MGI:5751612|PMID:26774822)

PMID:26774822

MGI:5751612

NCBI chr13:50,545,324...50,772,922
Ensembl chr13:50,545,836...50,770,601

Gata3

GATA binding protein 3

acts_upstream_of_or_within

(PMID:15087456)

PMID:15087456

NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391

interleukin 4

involved_in

(PMID:20554961)

PMID:20554961

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

Il6

interleukin 6

involved_in

(MGI:5795829|PMID:11159963)

PMID:11159963

MGI:5795829

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

NLR family, pyrin domain containing 3

involved_in

(MGI:5689221|PMID:26098997)

PMID:26098997

MGI:5689221

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

Prkcz

protein kinase C, zeta

involved_in

GO_REF:0000024
(MGI:3584076|PMID:15987782)

PMID:15987782

GO_REF:0000024 MGI:3584076

NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367

Rsad2

radical S-adenosyl methionine domain containing 2

involved_in

ISS
ISO
IEA

GO_REF:0000024
(MGI:3844206|PMID:19047684)
GO_REF:0000107

UniProt
RGD
Ensembl

PMID:19047684

GO_REF:0000024 GO_REF:0000107 MGI:3844206

NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699

X-C motif chemokine ligand 1

involved_in

GO_REF:0000107
(MGI:5009207|PMID:9973465)

PMID:9973465

GO_REF:0000107 MGI:5009207

NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329

positive regulation of T-helper 2 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Il18

interleukin 18

involved_in

GO_REF:0000107
(MGI:3608083|PMID:12829194)

PMID:12829194

GO_REF:0000107 MGI:3608083

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

Il4r

interleukin 4 receptor

acts_upstream_of_or_within

MGI:96109 (PMID:16424184)

PMID:16424184

NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980

Il6

interleukin 6

acts_upstream_of_or_within

(PMID:12594267)

PMID:12594267

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

NLR family, pyrin domain containing 3

involved_in

(MGI:5689221|PMID:26098997)

PMID:26098997

MGI:5689221

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

Prkcz

protein kinase C, zeta

involved_in

GO_REF:0000024
(MGI:3584076|PMID:15987782)

PMID:15987782

GO_REF:0000024 MGI:3584076

NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367

Rara

retinoic acid receptor, alpha

involved_in

(PMID:18416830)

PMID:18416830

NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142

TNF superfamily member 4

involved_in

(MGI:4943387|PMID:18354165)

PMID:18354165

MGI:4943387

NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788

positive regulation of T-helper cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Shb

SH2 domain containing adaptor protein B

acts_upstream_of_or_within

MGI:3721903 (PMID:24645804)

PMID:24645804

NCBI chr 5:59,678,066...59,785,443
Ensembl chr 5:59,678,216...59,785,538

positive regulation of type I hypersensitivity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Btk

Bruton tyrosine kinase

RGD

PMID:22228807

RGD:11040701

NCBI chr X:97,722,796...97,762,315
Ensembl chr X:97,722,802...97,761,853

Fcer1a

Fc epsilon receptor Ia

acts_upstream_of_or_within

MGI:2383982 (PMID:8252632)

PMID:8252632

NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351

Fc epsilon receptor Ig

acts_upstream_of_or_within

MGI:2384004 (PMID:14764707)

PMID:14764707

NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443

Fcgr2a

Fc gamma receptor 2A

acts_upstream_of_or_within

MGI:1861924 (PMID:8552190), (PMID:8769481), (PMID:9743367)

PMID:8552190 PMID:8769481 PMID:9743367

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

Ighg1

immunoglobulin heavy constant gamma 1

acts_upstream_of_or_within

(PMID:6952213), (PMID:8552190), (PMID:9743367)

PMID:6952213 PMID:8552190 PMID:9743367

Ensembl chr 6:132,389,370...132,393,397

positive regulation of type IIa hypersensitivity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

complement C3

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1861799 (PMID:11901193)

PMID:11901193

GO_REF:0000107

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

Fc epsilon receptor Ig

acts_upstream_of_or_within

MGI:1857165|MGI:2384004 (PMID:11901193), (PMID:11911824), (PMID:8976192)

PMID:8976192 PMID:11901193 PMID:11911824

NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443

Fcgr1a

Fc gamma receptor 1A

acts_upstream_of_or_within

MGI:2664927 (PMID:11911824)

PMID:11911824

NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994

Fcgr2a

Fc gamma receptor 2A

acts_upstream_of_or_within

MGI:1861924 (PMID:11911824), (PMID:9834201)

PMID:9834201 PMID:11911824

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

Ighg1

immunoglobulin heavy constant gamma 1

acts_upstream_of_or_within

(PMID:11901193), (PMID:9834201)

PMID:9834201 PMID:11901193

Ensembl chr 6:132,389,370...132,393,397

positive regulation of type III hypersensitivity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Btk

Bruton tyrosine kinase

RGD

PMID:22228807

RGD:11040701

NCBI chr X:97,722,796...97,762,315
Ensembl chr X:97,722,802...97,761,853

Fc epsilon receptor Ig

acts_upstream_of_or_within

MGI:1857165 (PMID:8976192)

PMID:8976192

NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443

Fcgr1a

Fc gamma receptor 1A

acts_upstream_of_or_within

MGI:2679238 (PMID:11911823)

PMID:11911823

NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994

Fcgr2a

Fc gamma receptor 2A

acts_upstream_of_or_within

MGI:1861924 (PMID:8769481)

HGNC
GO_Central
TreeGrafter
RGD

PMID:8769481

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

positive regulation of type IV hypersensitivity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Zp3

zona pellucida glycoprotein 3

involved_in

ISO
ISS
IEA

(PMID:15579591)
(MGI:4943411|PMID:15579591)
GO_REF:0000024
GO_REF:0000107

RGD
UniProt
Ensembl

PMID:15579591

GO_REF:0000024 GO_REF:0000107 MGI:4943411

NCBI chr12:20,690,547...20,697,513
Ensembl chr12:20,690,547...20,697,513

susceptibility to natural killer cell mediated cytotoxicity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cadm1

cell adhesion molecule 1

involved_in

ISS
IBA
IEA
ISO

GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
(MGI:3689781|PMID:15811952)
(PMID:15811952)

GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:3689781

NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833

nectin cell adhesion molecule 2

involved_in

(PMID:12913096)
GO_REF:0000033

GO_REF:0000033

NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360

PVR cell adhesion molecule

involved_in

(PMID:12913096)

NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715

Ulbp1

UL16 binding protein 1

acts_upstream_of_or_within

(PMID:12645935)

PMID:12645935

NCBI chr 1:1,694,255...1,716,160

susceptibility to T cell mediated cytotoxicity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

nectin cell adhesion molecule 2

involved_in

(PMID:15039383)
GO_REF:0000033

PMID:15039383

GO_REF:0000033

NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360

PVR cell adhesion molecule

involved_in

(PMID:15039383)