regulation of immune system process - Ontology Report

PMID:21873635

GO_Central

NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389

Bcl6b

BCL6B, transcription repressor

involved_in

PMID:21873635

GO_Central

NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974

Ceacam1

CEA cell adhesion molecule 1

involved_in

PMID:21873635

GO_Central

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

Ceacam20

CEA cell adhesion molecule 20

involved_in

PMID:21873635

GO_Central

NCBI chr 1:79,622,077...79,643,782
Ensembl chr 1:79,622,077...79,643,782

Ceacam4

CEA cell adhesion molecule 4

involved_in

PMID:21873635

GO_Central

NCBI chr 1:80,376,667...80,382,943
Ensembl chr 1:80,376,648...80,382,915

Ceacam6

CEA cell adhesion molecule 6

involved_in

PMID:21873635

GO_Central

NCBI chr 1:80,416,531...80,434,668
Ensembl chr 1:80,416,531...80,434,668

Cgm4

carcinoembryonic antigen gene family 4

involved_in

PMID:21873635

GO_Central

NCBI chr 1:77,776,447...77,789,408
Ensembl chr 1:77,776,447...77,789,396

Ggt1

gamma-glutamyltransferase 1

involved_in

IBA
IEA
ISO

PMID:21873635
GO_REF:0000107
(MGI:5294309|PMID:12468440)

PMID:12468440 PMID:21873635

GO_REF:0000107 MGI:5294309, RGD:13792537

NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442

Orm1

orosomucoid 1

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154

Pip

prolactin induced protein

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:5516489 (MGI:5516495|PMID:20052012)

PMID:20052012 PMID:21873635

MGI:5516495, RGD:13792537

NCBI chr 4:70,787,627...70,791,921
Ensembl chr 4:70,787,627...70,791,921

Psg29

pregnancy-specific glycoprotein 29

involved_in

PMID:21873635

GO_Central

NCBI chr 1:77,974,849...77,997,680
Ensembl chr 1:77,974,850...77,997,680

Psgb1

pregnancy-specific beta 1-glycoprotein

involved_in

PMID:21873635

GO_Central

NCBI chr 1:77,923,170...77,932,053
Ensembl chr 1:77,923,170...77,932,053

RT1-Ba

RT1 class II, locus Ba

involved_in

GO_REF:0000117

GO_REF:0000117

NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744

Siae

sialic acid acetylesterase

involved_in

(PMID:20555325)
GO_REF:0000107

PMID:20555325

GO_REF:0000107

NCBI chr 8:37,318,724...37,354,004
Ensembl chr 8:37,318,747...37,353,996

Sval1

seminal vesicle antigen-like 1

involved_in

PMID:21873635

GO_Central

NCBI chr 4:70,845,228...70,856,192
Ensembl chr 4:70,845,228...70,856,192

Sval2

seminal vesicle antigen-like 2

involved_in

PMID:21873635

GO_Central

NCBI chr 4:70,809,366...70,813,330
Ensembl chr 4:70,809,366...70,813,340

activation of immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Nod2

nucleotide-binding oligomerization domain containing 2

acts_upstream_of_or_within

MGI:3529594 (MGI:3528786|PMID:15692051)

PMID:15692051

MGI:3528786

NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177

Trex1

three prime repair exonuclease 1

acts_upstream_of_or_within

(MGI:3818783|PMID:18045533)

PMID:18045533

MGI:3818783

NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796

activation of innate immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Aim2

absent in melanoma 2

involved_in

PMID:21873635
(MGI:3839523|PMID:19158676)
(PMID:19158675), (PMID:19158676), (PMID:19158679)

PMID:19158675 PMID:19158676 PMID:19158679 PMID:21873635

MGI:3839523, RGD:13792537

NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975

Casp6

caspase 6

involved_in

(PMID:32298652)
GO_REF:0000024

PMID:32298652

GO_REF:0000024

NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502

Cgas

cyclic GMP-AMP synthase

involved_in

PMID:21873635
(PMID:23258413), (PMID:23929945), (PMID:24077100), (PMID:26046437), (PMID:28363908), (PMID:29426904), (PMID:30007416), (PMID:32817552), (PMID:32911482), (PMID:32912999), (PMID:33542149), (PMID:35438208)
(MGI:5487472|PMID:23258413), (MGI:5505711|PMID:23929945), (MGI:5908326|PMID:24077100), (MGI:6119245|PMID:29426904), (MGI:6754862|PMID:32911480), (MGI:6810288|PMID:32911481), (MGI:6828894|PMID:32913000)

MGI:5487472 MGI:5505711 MGI:5908326 MGI:6119245 MGI:6754862 MGI:6810288 MGI:6828894, RGD:13792537

PMID:23258413 PMID:23929945 PMID:24077100 PMID:26046437 PMID:28363908 More...

NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496

ENSRNOG00000069878

involved_in

GO_REF:0000002

GO_REF:0000002

Ensembl chr13:85,977,035...85,994,718

Hexim1

HEXIM P-TEFb complex subunit 1

involved_in

(PMID:28712728)

NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189

Hmgb1

high mobility group box 1

involved_in

(PMID:24971542)

PMID:24971542

NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565

Hsp90aa1

heat shock protein 90 alpha family class A member 1

involved_in

(PMID:20628368)
GO_REF:0000024

PMID:20628368

GO_REF:0000024

NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268

LOC102556096

pyrin domain-containing protein 3-like

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr13:85,911,915...85,929,491
Ensembl chr13:85,912,044...85,929,007

Matr3

matrin 3

involved_in

(PMID:28712728)

NCBI chr18:27,154,098...27,193,212
Ensembl chr18:27,163,714...27,193,166

Mavs

mitochondrial antiviral signaling protein

involved_in

(PMID:18818105), (PMID:20628368)
GO_REF:0000024

PMID:18818105 PMID:20628368

GO_REF:0000024

NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094

Mnda

myeloid cell nuclear differentiation antigen

involved_in

PMID:21873635

GO_Central

NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201

Nlrc4

NLR family, CARD domain containing 4

involved_in

GO_REF:0000024
(MGI:3662990|PMID:16648852)

PMID:16648852

GO_REF:0000024 MGI:3662990

NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248

Nono

non-POU domain containing, octamer-binding

involved_in

(PMID:28712728)

NCBI chr X:66,554,131...66,571,992
Ensembl chr X:66,554,098...66,571,952

Pqbp1

polyglutamine binding protein 1

involved_in

(PMID:26046437)
GO_REF:0000024

PMID:26046437

GO_REF:0000024

NCBI chr X:14,603,516...14,608,091
Ensembl chr X:14,603,539...14,608,087

Prkdc

protein kinase, DNA-activated, catalytic subunit

involved_in

(PMID:28712728)

NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952

Pspc1

paraspeckle component 1

involved_in

(PMID:28712728)

NCBI chr15:30,828,617...30,911,315
Ensembl chr15:30,828,626...30,911,202

Pycard

PYD and CARD domain containing

involved_in

(PMID:21575908)
(MGI:3839029|PMID:19158675)

PMID:19158675 PMID:21575908

MGI:3839029

NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955

Rbm14

RNA binding motif protein 14

involved_in

(PMID:28712728)

NCBI chr 1:202,076,940...202,105,688
Ensembl chr 1:202,078,287...202,105,665

RGD1562462

similar to Ifi204 protein

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr13:85,940,028...85,951,004
Ensembl chr13:85,940,078...85,951,004

Sfpq

splicing factor proline and glutamine rich

involved_in

(PMID:28712728)

NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472

Sin3a

SIN3 transcription regulator family member A

involved_in

(PMID:22783022)

PMID:18818105 PMID:21947006 PMID:23258412 PMID:23910378 PMID:21873635

PMID:22783022

NCBI chr 8:57,481,539...57,536,195
Ensembl chr 8:57,481,573...57,536,192

Sting1

stimulator of interferon response cGAMP interactor 1

involved_in

IBA
IEA
ISO

PMID:21873635
GO_REF:0000002
(MGI:5487473|PMID:23258412), (MGI:5487515|PMID:21947006), (MGI:6827194|PMID:23910378)
(PMID:18818105), (PMID:23910378)

InterPro
RGD

GO_REF:0000002 MGI:5487473 MGI:5487515 MGI:6827194, RGD:13792537

NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335

Tbk1

TANK-binding kinase 1

acts_upstream_of_or_within

MGI:3046789 (MGI:3530402|PMID:15661922)

PMID:15661922

MGI:3530402

NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892

Tlr4

toll-like receptor 4

acts_upstream_of_or_within

MGI:1860885 (MGI:3530402|PMID:15661922)

PMID:15661922

MGI:3530402

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

Tlr9

toll-like receptor 9

involved_in

(MGI:5887188|PMID:25686612)

PMID:25686612

MGI:5887188

NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796

Tomm70

translocase of outer mitochondrial membrane 70

involved_in

IEA
ISS
ISO

GO_REF:0000107
GO_REF:0000024
(PMID:20628368)

Ensembl
UniProt
RGD

PMID:20628368

GO_REF:0000024 GO_REF:0000107

NCBI chr11:43,378,719...43,417,166
Ensembl chr11:43,377,216...43,417,202

Trim5

tripartite motif-containing 5

involved_in

(PMID:21512573)

PMID:21512573

NCBI chr 1:158,720,407...158,737,393
Ensembl chr 1:158,720,410...158,814,012

Xrcc5

X-ray repair cross complementing 5

involved_in

(PMID:28712728)

NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018

Xrcc6

X-ray repair cross complementing 6

involved_in

(PMID:28712728)

NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762

Zbp1

Z-DNA binding protein 1

involved_in

GO_REF:0000024
(MGI:6434626|PMID:32296175), (MGI:6436412|PMID:32200799), (MGI:6453154|PMID:32350114), (MGI:6490907|PMID:33109609)

PMID:32200799 PMID:32296175 PMID:32350114 PMID:33109609

GO_REF:0000024 MGI:6434626 MGI:6436412 MGI:6453154 MGI:6490907

NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870

Zcchc3

zinc finger CCHC-type containing 3

involved_in

(PMID:30135424), (PMID:30193849)
PMID:21873635
(MGI:6209107|PMID:30135424), (MGI:6271678|PMID:30193849)

PMID:30135424 PMID:30193849 PMID:21873635

MGI:6209107 MGI:6271678, RGD:13792537

NCBI chr 3:140,872,460...140,875,851
Ensembl chr 3:140,872,460...140,882,408

Znfx1

zinc finger, NFX1-type containing 1

involved_in

(MGI:6384069|PMID:31685995)

PMID:31685995

MGI:6384069

NCBI chr 3:155,764,073...155,791,777
Ensembl chr 3:155,764,980...155,821,242

activation of membrane attack complex

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cfh

complement factor H

acts_upstream_of_or_within

(MGI:4837299|PMID:20813971)

PMID:20813971

MGI:4837299

NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838

antigen receptor-mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bcar1

BCAR1 scaffold protein, Cas family member

involved_in

(PMID:10587647)
GO_REF:0000024

PMID:10587647

GO_REF:0000024

NCBI chr19:39,679,218...39,713,952
Ensembl chr19:39,679,204...39,713,907

Cd19

CD19 molecule

involved_in

(PMID:1373518)

PMID:1373518

NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975

Lax1

lymphocyte transmembrane adaptor 1

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:3579135 (MGI:3578441|PMID:15843560)

PMID:15843560 PMID:21873635

MGI:3578441, RGD:13792537

NCBI chr13:45,134,825...45,145,381
Ensembl chr13:45,134,834...45,145,381

Sh2b2

SH2B adaptor protein 2

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:1859033|PMID:10872802)

PMID:10872802 PMID:21873635

MGI:1859033, RGD:13792537

NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844

B cell costimulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd320

CD320 molecule

involved_in

(PMID:10727470)
GO_REF:0000024

PMID:10727470

GO_REF:0000024

NCBI chr 7:14,626,171...14,631,976
Ensembl chr 7:14,609,146...14,631,976

Il4

interleukin 4

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:3817382|PMID:18762567)

PMID:18762567 PMID:21873635

MGI:3817382, RGD:13792537

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

Tnfrsf13c

TNF receptor superfamily member 13C

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:3051152|PMID:15240667)

PMID:15240667 PMID:21873635

MGI:3051152, RGD:13792537

NCBI chr 7:113,736,046...113,738,523
Ensembl chr 7:113,736,055...113,738,517

Tnfsf13b

TNF superfamily member 13b

acts_upstream_of_or_within

(MGI:3051152|PMID:15240667)

PMID:15240667

MGI:3051152

NCBI chr16:79,462,406...79,492,888
Ensembl chr16:79,462,402...79,492,693

B cell receptor apoptotic signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bax

BCL2 associated X, apoptosis regulator

involved_in

(PMID:15214043)

PMID:15214043

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

Nfkbiz

NFKB inhibitor zeta

involved_in

(MGI:5508814|PMID:23728777)

PMID:23728777

MGI:5508814

NCBI chr11:44,782,676...44,810,723
Ensembl chr11:44,782,676...44,810,723

B cell receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AABR07065781.1

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:134,488,094...134,488,587

AABR07065782.1

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:134,539,974...134,540,303

AABR07065789.1

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:134,872,774...134,873,270

AABR07065808.1

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,178,938...135,179,469

AABR07065812.2

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,387,664...135,388,140

AABR07065813.1

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,538,767...135,568,573

AABR07065814.2

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,592,956...135,593,464

AABR07065823.2

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:136,095,796...136,096,294

Abl1

ABL proto-oncogene 1, non-receptor tyrosine kinase

acts_upstream_of_or_within

MGI:2153718 (MGI:1927957|PMID:11120811), (MGI:3839222|PMID:19228876)

PMID:11120811 PMID:19228876

MGI:1927957 MGI:3839222

NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065

AC109737.1

involved_in

PMID:21873635

GO_Central

Ensembl chr 4:70,417,612...70,418,013

Bcar1

BCAR1 scaffold protein, Cas family member

involved_in

ISO
IEA
ISS

(PMID:9020138)
GO_REF:0000107
GO_REF:0000024

RGD
Ensembl
UniProt

PMID:9020138

GO_REF:0000024 GO_REF:0000107

NCBI chr19:39,679,218...39,713,952
Ensembl chr19:39,679,204...39,713,907

Bcl2

BCL2, apoptosis regulator

involved_in

(PMID:17875758)

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

Blk

BLK proto-oncogene, Src family tyrosine kinase

involved_in

UniProtKB:Q8NDB2 (PMID:23555801), (PMID:876631)

PMID:876631 PMID:23555801

NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031

Blnk

B-cell linker

involved_in

(PMID:11606584), (PMID:9697839)

PMID:9697839 PMID:11606584

NCBI chr 1:239,753,640...239,821,113
Ensembl chr 1:239,753,648...239,821,113

Bmx

BMX non-receptor tyrosine kinase

involved_in

PMID:21873635

GO_Central

NCBI chr X:30,227,251...30,290,015
Ensembl chr X:30,227,251...30,289,993

Btk

Bruton tyrosine kinase

involved_in

(PMID:15509800)

PMID:15509800

NCBI chr X:97,722,796...97,762,315
Ensembl chr X:97,722,802...97,761,853

Cd19

CD19 molecule

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:1095647|PMID:9254656)
(MGI:5476553|PMID:23499492)

PMID:9254656 PMID:23499492 PMID:21873635

MGI:1095647 MGI:5476553, RGD:13792537

NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975

Cd38

CD38 molecule

involved_in

(PMID:17875758)

NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986

Cd79a

CD79a molecule

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:79455|PMID:8626447)
(MGI:3521842|PMID:1373499), (MGI:79455|PMID:8626447)

PMID:1373499 PMID:8626447 PMID:21873635

MGI:3521842 MGI:79455, RGD:13792537

NCBI chr 1:80,493,520...80,497,936
Ensembl chr 1:80,493,581...80,497,935

Cd79b

CD79b molecule

acts_upstream_of_or_within
involved_in

(MGI:3521842|PMID:1373499), (MGI:79455|PMID:8626447)
(MGI:79455|PMID:8626447)
PMID:21873635

PMID:1373499 PMID:8626447 PMID:21873635

MGI:3521842 MGI:79455, RGD:13792537

NCBI chr10:91,239,354...91,242,500
Ensembl chr10:91,239,356...91,242,625

Ctla4

cytotoxic T-lymphocyte-associated protein 4

involved_in

PMID:21873635
(PMID:17875758)

PMID:17875758 PMID:21873635

NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963

ENSRNOG00000062324

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:136,773,301...136,773,764

ENSRNOG00000065283

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:134,800,826...134,801,328

ENSRNOG00000066076

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,829,858...135,830,364

ENSRNOG00000066380

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:134,657,094...134,657,417

ENSRNOG00000066892

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:134,160,101...134,160,632

ENSRNOG00000067010

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:136,881,681...136,882,341

ENSRNOG00000068279

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:134,906,155...134,906,642

ENSRNOG00000068413

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,721,402...135,721,710

ENSRNOG00000068908

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,089,336...135,089,786

ENSRNOG00000069071

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,988,836...135,989,350

ENSRNOG00000069250

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,916,486...135,916,803

ENSRNOG00000070949

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:136,217,851...136,218,303

Fcrl5

Fc receptor-like 5

acts_upstream_of

MGI:96055|MGI:96892 (MGI:5471851|PMID:23509253)

PMID:23509253

MGI:5471851

NCBI chr 2:172,881,763...172,912,912
Ensembl chr 2:172,881,448...172,913,148

Grb2

growth factor receptor bound protein 2

involved_in

(MGI:7316616|PMID:9199344)

PMID:9199344

MGI:7316616

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

IgG-2a

gamma-2a immunoglobulin heavy chain

involved_in

PMID:21873635

GO_Central

Igh-6

immunoglobulin heavy chain 6

involved_in

PMID:21873635

GO_Central

Igh-6-ps1

immunoglobulin heavy chain 6, pseudogene 1

involved_in

PMID:21873635

GO_Central

NCBI chr 6:136,154,202...136,187,939
Ensembl chr 6:136,187,348...136,187,728

Ighg1

immunoglobulin heavy constant gamma 1

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:132,389,370...132,393,397

Ighm

immunoglobulin heavy constant epsilon

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:132,329,269...133,053,426

Igkc

immunoglobulin kappa constant

involved_in

PMID:21873635

GO_Central

Iglc1

immunoglobulin lambda constant 1

involved_in

PMID:21873635

GO_Central

NCBI chr11:81,947,966...81,949,822
Ensembl chr11:81,947,934...81,949,822

Igll1

immunoglobulin lambda-like polypeptide 1

involved_in

PMID:21873635

GO_Central

NCBI chr11:84,138,847...84,142,238
Ensembl chr11:84,138,910...84,142,216

Itk

IL2-inducible T-cell kinase

involved_in

PMID:21873635

GO_Central

NCBI chr10:30,753,339...30,814,685
Ensembl chr10:30,753,344...30,814,685

Klhl6

kelch-like family member 6

involved_in

(MGI:3603885|PMID:16166635)

PMID:16166635

MGI:3603885

NCBI chr11:80,970,917...81,010,593
Ensembl chr11:80,970,917...81,009,677

Lat2

linker for activation of T cells family, member 2

involved_in

(PMID:12514734)
PMID:21873635

PMID:12514734 PMID:21873635

NCBI chr12:22,104,163...22,118,294
Ensembl chr12:22,104,219...22,118,288

Lck

LCK proto-oncogene, Src family tyrosine kinase

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:77358|PMID:7499277)

PMID:7499277 PMID:21873635

MGI:77358, RGD:13792537

NCBI chr 5:141,888,319...141,916,992
Ensembl chr 5:141,888,326...141,903,794

Lime1

Lck interacting transmembrane adaptor 1

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:3769059|PMID:16249387)

PMID:16249387 PMID:21873635

MGI:3769059, RGD:13792537

NCBI chr 3:168,490,535...168,496,627
Ensembl chr 3:168,490,074...168,493,127

LOC100360761

rCG64219-like

involved_in

PMID:21873635

GO_Central

NCBI chr 6:134,328,070...134,328,632
Ensembl chr 6:134,328,064...134,358,517

LOC100361324

hypothetical LOC100361324

involved_in

PMID:21873635

GO_Central

NCBI chr 6:134,584,503...134,585,017
Ensembl chr 6:134,584,503...134,585,002

LOC362795

immunoglobulin G heavy chain

involved_in

PMID:21873635

GO_Central

LYN proto-oncogene, Src family tyrosine kinase

acts_upstream_of_or_within

MGI:3053558 (MGI:5471851|PMID:23509253), (MGI:77358|PMID:7499277)

PMID:7499277 PMID:23509253

MGI:5471851 MGI:77358

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

Mapk1

mitogen activated protein kinase 1

acts_upstream_of_or_within

(MGI:1095647|PMID:9254656)

PMID:9254656

MGI:1095647

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

Mef2c

myocyte enhancer factor 2C

involved_in

GO_REF:0000024
(MGI:3829850|PMID:18955699)

PMID:18955699

GO_REF:0000024 MGI:3829850

NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880

Mnda

myeloid cell nuclear differentiation antigen

involved_in

(PMID:17875758)

NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201

Ms4a1

membrane spanning 4-domains A1

involved_in

(PMID:18474602)

PMID:18474602

NCBI chr 1:207,906,370...207,927,028
Ensembl chr 1:207,906,374...207,918,512

Nckap1l

NCK associated protein 1 like

involved_in

GO_REF:0000024
(PMID:17875758)

GO_REF:0000024

NCBI chr 7:134,577,443...134,622,934
Ensembl chr 7:134,577,482...134,622,934

Nfam1

NFAT activating protein with ITAM motif 1

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:3044463|PMID:15143214)

PMID:15143214 PMID:21873635

MGI:3044463, RGD:13792537

NCBI chr 7:114,139,318...114,175,395
Ensembl chr 7:114,139,345...114,175,442

Nfatc2

nuclear factor of activated T-cells 2

involved_in

(PMID:17875758)

NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325

Nfkb1

nuclear factor kappa B subunit 1

involved_in

(MGI:3710273|PMID:17367755)

PMID:17367755

MGI:3710273

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

Nfkbia

NFKB inhibitor alpha

involved_in

(MGI:3710273|PMID:17367755)

PMID:17367755

MGI:3710273

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

Nfkbiz

NFKB inhibitor zeta

involved_in

(MGI:3710273|PMID:17367755)

PMID:17367755

MGI:3710273

NCBI chr11:44,782,676...44,810,723
Ensembl chr11:44,782,676...44,810,723

Plcg2

phospholipase C, gamma 2

involved_in

GO_REF:0000107
(PMID:11606584), (PMID:15509800)
(MGI:1861532|PMID:10925250)

PMID:10925250 PMID:11606584 PMID:15509800

GO_REF:0000107 MGI:1861532

NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930

Plekha1

pleckstrin homology domain containing A1

involved_in

(PMID:12101241)

PMID:12101241

NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156

Prkcb

protein kinase C, beta

involved_in

ISS
ISO
IEA

GO_REF:0000024
(MGI:3626015|PMID:12118249)
GO_REF:0000107

UniProt
RGD
Ensembl

PMID:12118249

GO_REF:0000024 GO_REF:0000107 MGI:3626015

NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1856074|MGI:3053558 (MGI:1095647|PMID:9254656), (MGI:5471851|PMID:23509253)

PMID:9254656 PMID:23509253

GO_REF:0000107 MGI:1095647 MGI:5471851

NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984

Ptprc

protein tyrosine phosphatase, receptor type, C

involved_in
acts_upstream_of_or_within

GO_REF:0000024
MGI:2181288 (MGI:1095647|PMID:9254656), (MGI:77358|PMID:7499277)
(MGI:3687418|PMID:8692271)

PMID:7499277 PMID:8692271 PMID:9254656

GO_REF:0000024 MGI:1095647 MGI:3687418 MGI:77358

NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692

Rftn1

raftlin lipid raft linker 1

involved_in

(PMID:12805216)

PMID:12805216

NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084

RGD1564318

similar to immunoglobulin light chain variable region

involved_in

PMID:21873635

GO_Central

Sh2b2

SH2B adaptor protein 2

involved_in
acts_upstream_of_or_within

(PMID:9233773)
(MGI:1859033|PMID:10872802)

PMID:9233773 PMID:10872802

MGI:1859033

NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844

Shc1

SHC adaptor protein 1

involved_in

(MGI:7316616|PMID:9199344)

PMID:9199344

MGI:7316616

NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536

Sos1

SOS Ras/Rac guanine nucleotide exchange factor 1

involved_in

MGI:98355 (MGI:5547878|PMID:24043312)

PMID:7499277 PMID:8626447 PMID:9199344 PMID:15509800 PMID:21873635

PMID:24043312

MGI:5547878

NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107

Syk

spleen associated tyrosine kinase

involved_in
acts_upstream_of_or_within

IEA
ISO
IBA
ISS

GO_REF:0000107
(MGI:7316616|PMID:9199344)
PMID:21873635
(PMID:15509800)
(MGI:77358|PMID:7499277), (MGI:79455|PMID:8626447)
GO_REF:0000024

Ensembl
RGD
UniProt

GO_REF:0000024 GO_REF:0000107 MGI:7316616 MGI:77358 MGI:79455, RGD:13792537

NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410

Tec

tec protein tyrosine kinase

involved_in

PMID:21873635
(PMID:10518561)

PMID:10518561 PMID:21873635

NCBI chr14:35,352,551...35,461,585
Ensembl chr14:35,352,829...35,461,557

Vav3

vav guanine nucleotide exchange factor 3

involved_in

(PMID:17875758)

NCBI chr 2:197,011,901...197,354,321
Ensembl chr 2:197,011,831...197,354,321

CD4-positive, alpha-beta T cell costimulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd81

Cd81 molecule

involved_in

(PMID:22307619)
GO_REF:0000024

PMID:22307619

GO_REF:0000024

NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660

Tnfsf4

TNF superfamily member 4

involved_in

(MGI:4819294|PMID:20639485)

PMID:20639485

MGI:4819294

NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788

cell surface pattern recognition receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd14

CD14 molecule

involved_in

(PMID:15294986)

PMID:15294986

NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261

Clec7a

C-type lectin domain containing 7A

acts_upstream_of_or_within

(MGI:3042099|PMID:12719478)

PMID:12719478

MGI:3042099

NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897

Fcna

ficolin A

involved_in

ISS

GO_REF:0000024

GO_REF:0000024

NCBI chr 3:8,445,904...8,449,128
Ensembl chr 3:8,445,907...8,449,105

Fcnb

ficolin B

involved_in

(PMID:21037097)

PMID:21037097

NCBI chr 3:11,393,771...11,402,198
Ensembl chr 3:11,393,739...11,402,151

Ffar2

free fatty acid receptor 2

involved_in

(PMID:21037097)
GO_REF:0000024

PMID:21037097

GO_REF:0000024

NCBI chr 1:86,071,860...86,075,049
Ensembl chr 1:86,072,184...86,075,033

Lbp

lipopolysaccharide binding protein

involved_in

(PMID:15294986)

PMID:15294986

NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586

MBL associated serine protease 1

involved_in

(PMID:22966085)

PMID:22966085

NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974

MBL associated serine protease 2

involved_in

(PMID:22966085)

PMID:22966085

NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580

Mbl2

mannose binding lectin 2

involved_in

(PMID:22966085)

PMID:22966085

NCBI chr 1:228,016,439...228,024,736

Tlr2

toll-like receptor 2

acts_upstream_of_or_within

MGI:2178675 (MGI:3042099|PMID:12719478)

PMID:12719478

MGI:3042099

NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630

complement activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

C1r

complement C1r

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484

C1s

complement C1s

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303

complement C2

involved_in

(PMID:19302245)
PMID:21873635
(PMID:12878586), (PMID:6906228)

PMID:6906228 PMID:12878586 PMID:19302245 PMID:21873635

NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505

complement C3

involved_in
acts_upstream_of_or_within

IDA
ISO
IBA

(PMID:12878586), (PMID:6225800)
(MGI:3833206|PMID:18947875), (MGI:5617896|PMID:25284781)
PMID:21873635
(PMID:19302245)

MGI:3833206 MGI:5617896, RGD:5129529, RGD:13792537

PMID:6225800 PMID:12878586 PMID:18947875 PMID:19302245 PMID:25284781 More...

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

C4a

complement C4A

involved_in
acts_upstream_of_or_within

TAS
ISO
IBA

(PMID:12878586), (PMID:6906228)
(MGI:51812|PMID:1438267), (MGI:66045|PMID:8133084)
UniProtKB:P0C0L5 (PMID:19302245)
PMID:21873635

PMID:1438267 PMID:6906228 PMID:8133084 PMID:12878586 PMID:19302245 More...

MGI:51812 MGI:66045, RGD:1302926, RGD:13792537

NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080

C4b

complement C4B (Chido blood group)

involved_in
acts_upstream_of_or_within

PMID:21873635
(PMID:12878586), (PMID:6906228)
MGI:1889070 (MGI:2429478|PMID:12421924)
UniProtKB:P0C0L4|UniProtKB:P0C0L5 (PMID:19302245)

PMID:6906228 PMID:12421924 PMID:12878586 PMID:19302245 PMID:21873635

MGI:2429478, RGD:13792537

NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681

complement C5

involved_in

(PMID:2808363)

PMID:2808363

NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994

complement C6

involved_in

(PMID:2808363)
PMID:21873635

PMID:2808363 PMID:21873635

NCBI chr 2:53,846,027...53,921,279
Ensembl chr 2:53,851,985...53,921,275

C8a

complement C8 alpha chain

acts_upstream_of_or_within
involved_in

(PMID:12413696)
PMID:21873635

PMID:12413696 PMID:21873635

NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754

C8b

complement C8 beta chain

involved_in

PMID:21873635

GO_Central

NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565

C8g

complement C8 gamma chain

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:8,320,495...8,323,495
Ensembl chr 3:8,305,920...8,323,495

complement C9

involved_in

PMID:21873635

GO_Central

PMID:6906329 PMID:21873635

NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338

Cfb

complement factor B

involved_in

IDA
IBA

PMID:21873635

RGD
GO_Central

RGD:2311339, RGD:13792537

NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505

Cfh

complement factor H

acts_upstream_of_or_within
involved_in

IEP
ISO
IBA

MGI:3639077 MGI:3760048 MGI:3760334 MGI:3848672 MGI:3849508 MGI:4821502 MGI:4830025 MGI:5883383, RGD:1599888, RGD:13792537

PMID:15574507 PMID:17517971 PMID:17921253 PMID:19411110 PMID:19541934 More...

NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838

Cfhr1

complement factor H-related 1

involved_in

PMID:21873635

GO_Central

NCBI chr13:51,395,583...51,410,571
Ensembl chr13:51,369,211...51,410,592

Cfhr2

complement factor H-related 2

involved_in

PMID:21873635

GO_Central

NCBI chr13:51,175,824...51,247,924
Ensembl chr13:51,175,841...51,247,495

Cfhr4

complement factor H-related 4

involved_in

PMID:21873635

GO_Central

NCBI chr13:51,422,592...51,491,476
Ensembl chr13:51,422,592...51,491,502

Cfi

complement factor I

involved_in

(MGI:3773599|PMID:18202746)

PMID:18202746

MGI:3773599

NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561

Colec11

collectin sub-family member 11

involved_in

(PMID:23954398)

PMID:23954398

NCBI chr 6:45,223,974...45,256,640
Ensembl chr 6:45,223,980...45,271,145

complement C3b/C4b receptor 1 like

acts_upstream_of_or_within

(MGI:4821502|PMID:20675597)

PMID:20675597

MGI:4821502

NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445

Fcna

ficolin A

involved_in

(PMID:22851708)

PMID:22851708

NCBI chr 3:8,445,904...8,449,128
Ensembl chr 3:8,445,907...8,449,105

Lcn12

lipocalin 12

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr 3:8,312,404...8,320,206
Ensembl chr 3:8,305,920...8,323,495

MBL associated serine protease 1

involved_in

NAS
IEA

GO_REF:0000002

InterPro
RGD

PMID:12847554

GO_REF:0000002, RGD:633273

NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974

MBL associated serine protease 2

NAS

RGD

PMID:10586086

RGD:633276

NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580

Rgcc

regulator of cell cycle

involved_in

(PMID:19162005)

PMID:19162005

NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141

complement activation, alternative pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

complement C3

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

complement C5

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994

C8a

complement C8 alpha chain

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754

C8b

complement C8 beta chain

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565

complement C9

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338

Cfb

complement factor B

acts_upstream_of_or_within

MGI:1861129 (MGI:1096110|PMID:9238044), (MGI:6100611|PMID:27564415)

PMID:9238044 PMID:27564415

MGI:1096110 MGI:6100611

NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505

Cfd

complement factor D

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:6100611|PMID:27564415)

PMID:27564415

GO_REF:0000107 MGI:6100611

NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053

Cfh

complement factor H

acts_upstream_of_or_within_negative_effect

(MGI:4421084|PMID:19828624)
(MGI:6100611|PMID:27564415)

PMID:19828624 PMID:27564415

MGI:4421084 MGI:6100611

NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838

Cfp

complement factor properdin

involved_in

MGI:3774548 (MGI:3773929|PMID:18292556)

PMID:18292556

MGI:3773929

NCBI chr X:1,162,014...1,167,576
Ensembl chr X:1,161,979...1,167,573

Cr2

complement C3d receptor 2

involved_in
acts_upstream_of_or_within_negative_effect

(PMID:11981823)
(MGI:4421084|PMID:19828624)

PMID:11981823 PMID:19828624

MGI:4421084

NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235

RGD1308742

similar to Complement C5 precursor

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:18,401,716...18,420,064
Ensembl chr 3:18,404,899...18,420,054

complement activation, classical pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AABR07006691.1

involved_in

GO_REF:0000043

GO_REF:0000043

Ensembl chr 1:228,016,498...228,043,066

AABR07065781.1

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:134,488,094...134,488,587

AABR07065782.1

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:134,539,974...134,540,303

AABR07065789.1

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:134,872,774...134,873,270

AABR07065808.1

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,178,938...135,179,469

AABR07065812.2

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,387,664...135,388,140

AABR07065813.1

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,538,767...135,568,573

AABR07065814.2

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,592,956...135,593,464

AABR07065823.2

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:136,095,796...136,096,294

AC109737.1

involved_in

PMID:21873635

GO_Central

Ensembl chr 4:70,417,612...70,418,013

C1qa

complement C1q A chain

acts_upstream_of_or_within
involved_in

MGI:2158701 (MGI:2177393|PMID:11901193)
GO_REF:0000107
(PMID:29449492)

PMID:11901193 PMID:29449492

GO_REF:0000107 MGI:2177393

NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534

C1qb

complement C1q B chain

involved_in

(PMID:29449492)

PMID:29449492

NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407

C1qbp

complement C1q binding protein

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649

C1qc

complement C1q C chain

involved_in

(PMID:29449492)
GO_REF:0000107

PMID:29449492

GO_REF:0000107

NCBI chr 5:149,127,424...149,130,732
Ensembl chr 5:149,127,415...149,131,017

C1rl

complement C1r subcomponent like

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 4:157,394,183...157,410,771
Ensembl chr 4:157,394,200...157,410,134

C1s

complement C1s

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303

complement C2

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505

complement C3

involved_in

TAS
IEA

GO_REF:0000043

UniProt
RGD

PMID:16996480

GO_REF:0000043, RGD:1600605

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

C4a

complement C4A

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080

C4b

complement C4B (Chido blood group)

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681

C4bpa

complement component 4 binding protein, alpha

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205

C4bpb

complement component 4 binding protein, beta

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817

complement C5

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994

complement C6

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:53,846,027...53,921,279
Ensembl chr 2:53,851,985...53,921,275

C8a

complement C8 alpha chain

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754

C8b

complement C8 beta chain

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565

complement C9

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338

Cfb

complement factor B

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505

Cfi

complement factor I

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561

complement C3b/C4b receptor 1 like

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445

C-reactive protein

RGD

NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178

ENSRNOG00000062324

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:136,773,301...136,773,764

ENSRNOG00000065283

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:134,800,826...134,801,328

ENSRNOG00000066076

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,829,858...135,830,364

ENSRNOG00000066380

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:134,657,094...134,657,417

ENSRNOG00000066892

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:134,160,101...134,160,632

ENSRNOG00000067010

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:136,881,681...136,882,341

ENSRNOG00000068279

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:134,906,155...134,906,642

ENSRNOG00000068413

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,721,402...135,721,710

ENSRNOG00000068908

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,089,336...135,089,786

ENSRNOG00000069071

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,988,836...135,989,350

ENSRNOG00000069250

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:135,916,486...135,916,803

ENSRNOG00000070949

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:136,217,851...136,218,303

IgG-2a

gamma-2a immunoglobulin heavy chain

involved_in

PMID:21873635

GO_Central

Igh-6

immunoglobulin heavy chain 6

involved_in

PMID:21873635

GO_Central

Igh-6-ps1

immunoglobulin heavy chain 6, pseudogene 1

involved_in

PMID:21873635

GO_Central

NCBI chr 6:136,154,202...136,187,939
Ensembl chr 6:136,187,348...136,187,728

Ighg1

immunoglobulin heavy constant gamma 1

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:2683928|PMID:6952213)

PMID:6952213 PMID:21873635

MGI:2683928, RGD:13792537

Ensembl chr 6:132,389,370...132,393,397

Ighm

immunoglobulin heavy constant epsilon

involved_in

PMID:21873635

GO_Central

Ensembl chr 6:132,329,269...133,053,426

Igkc

immunoglobulin kappa constant

involved_in

PMID:21873635

GO_Central

Iglc1

immunoglobulin lambda constant 1

involved_in

PMID:21873635

GO_Central

NCBI chr11:81,947,966...81,949,822
Ensembl chr11:81,947,934...81,949,822

Igll1

immunoglobulin lambda-like polypeptide 1

involved_in

PMID:21873635

GO_Central

NCBI chr11:84,138,847...84,142,238
Ensembl chr11:84,138,910...84,142,216

LOC100360761

rCG64219-like

involved_in

PMID:21873635

GO_Central

NCBI chr 6:134,328,070...134,328,632
Ensembl chr 6:134,328,064...134,358,517

LOC100361324

hypothetical LOC100361324

involved_in

PMID:21873635

GO_Central

NCBI chr 6:134,584,503...134,585,017
Ensembl chr 6:134,584,503...134,585,002

LOC362795

immunoglobulin G heavy chain

involved_in

PMID:21873635

GO_Central

MBL associated serine protease 2

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580

Mbl1

mannose binding lectin 1

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr16:17,029,146...17,035,187
Ensembl chr16:17,029,118...17,035,174

Mbl2

mannose binding lectin 2

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 1:228,016,439...228,024,736

RGD1308742

similar to Complement C5 precursor

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:18,401,716...18,420,064
Ensembl chr 3:18,404,899...18,420,054

RGD1564318

similar to immunoglobulin light chain variable region

involved_in

PMID:21873635

GO_Central

Serping1

serpin family G member 1

involved_in

GO_REF:0000043

GO_REF:0000043

NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034

complement activation, lectin pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AABR07006691.1

involved_in

GO_REF:0000043

PMID:11034393 PMID:15506986

GO_REF:0000043

Ensembl chr 1:228,016,498...228,043,066

Cd69

Cd69 molecule

TAS

RGD

RGD:1354527, RGD:1354528

NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542

Colec10

collectin subfamily member 10

involved_in

(PMID:24174618)

PMID:24174618

NCBI chr 7:85,744,895...85,806,368
Ensembl chr 7:85,744,895...85,805,675

Colec11

collectin sub-family member 11

involved_in

(PMID:24174618), (PMID:25912189)

PMID:24174618 PMID:25912189

NCBI chr 6:45,223,974...45,256,640
Ensembl chr 6:45,223,980...45,271,145

Fcna

ficolin A

involved_in
acts_upstream_of_or_within

(PMID:11907111)
PMID:21873635
(MGI:5473786|PMID:16328467)

PMID:11907111 PMID:16328467 PMID:21873635

MGI:5473786, RGD:13792537

NCBI chr 3:8,445,904...8,449,128
Ensembl chr 3:8,445,907...8,449,105

Fcnb

ficolin B

involved_in

(PMID:16116205)
PMID:21873635

PMID:16116205 PMID:21873635

NCBI chr 3:11,393,771...11,402,198
Ensembl chr 3:11,393,739...11,402,151

Krt1

keratin 1

involved_in

UniProtKB:P11226 (PMID:11549596)
GO_REF:0000107

PMID:11549596

GO_REF:0000107

NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844

MBL associated serine protease 1

involved_in

IBA
ISO
ISS

PMID:21873635
(PMID:10679061), (PMID:11907111), (PMID:16116205), (PMID:22691502), (PMID:24174618)
(MGI:3789229|PMID:18424734)
(PMID:17182967)
GO_REF:0000024

PMID:10679061 PMID:11907111 PMID:16116205 PMID:17182967 PMID:18424734 More...

GO_REF:0000024 MGI:3789229, RGD:13792537

NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974

MBL associated serine protease 2

involved_in
acts_upstream_of_or_within

ISO
IBA
IEA

(PMID:17182967), (PMID:9087411)
PMID:21873635
(PMID:10679061), (PMID:11907111), (PMID:16116205), (PMID:22691502), (PMID:24174618)
(MGI:5473786|PMID:16328467)
GO_REF:0000107

PMID:9087411 PMID:10679061 PMID:11907111 PMID:16116205 PMID:16328467 More...

GO_REF:0000107 MGI:5473786, RGD:13792537

NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580

Mbl1

mannose binding lectin 1

acts_upstream_of_or_within

IDA
ISO

MGI:96924 (MGI:3577322|PMID:15148336)

PMID:15148336 PMID:16272342

MGI:3577322, RGD:1582134

NCBI chr16:17,029,146...17,035,187
Ensembl chr16:17,029,118...17,035,174

Mbl2

mannose binding lectin 2

acts_upstream_of_or_within
involved_in

MGI:3577339|MGI:96923 (MGI:3577322|PMID:15148336)
UniProtKB:P04264 (PMID:11549596), (PMID:22691502), (PMID:35102342)
(PMID:15148336)

PMID:11549596 PMID:15148336 PMID:22691502 PMID:35102342

MGI:3577322

NCBI chr 1:228,016,439...228,024,736

complement component C5a signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

C5ar1

complement C5a receptor 1

involved_in
acts_upstream_of_or_within

(PMID:10571060)
(MGI:51391|PMID:1401897)

PMID:1401897 PMID:10571060

MGI:51391

NCBI chr 1:76,948,622...76,959,826

C5ar2

complement C5a receptor 2

involved_in

GO_REF:0000108

GO_REF:0000108

NCBI chr 1:76,930,381...76,945,432
Ensembl chr 1:76,930,383...76,959,517

complement receptor mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

C3ar1

complement C3a receptor 1

involved_in

IEA
IBA
ISO

GO_REF:0000107
PMID:21873635
(PMID:10571060)

PMID:10571060 PMID:21873635

GO_REF:0000107, RGD:13792537

NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701

C5ar1

complement C5a receptor 1

involved_in

PMID:21873635

GO_Central

NCBI chr 1:76,948,622...76,959,826

C5ar2

complement C5a receptor 2

involved_in

IBA
IEA

PMID:21873635
GO_REF:0000108

GO_REF:0000108, RGD:13792537

NCBI chr 1:76,930,381...76,945,432
Ensembl chr 1:76,930,383...76,959,517

Cmklr1

chemerin chemokine-like receptor 1

involved_in

PMID:21873635

GO_Central

NCBI chr12:42,974,462...43,027,321
Ensembl chr12:42,974,410...43,028,129

Cr2

complement C3d receptor 2

acts_upstream_of_or_within

MGI:2154453 (MGI:2154602|PMID:11728339)

PMID:11728339

MGI:2154602

NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235

Fpr1

formyl peptide receptor 1

involved_in

PMID:21873635

GO_Central

NCBI chr 1:58,745,019...58,756,776
Ensembl chr 1:58,747,246...58,756,559

Fpr2

formyl peptide receptor 2

involved_in

PMID:21873635

GO_Central

NCBI chr 1:58,776,592...58,785,227
Ensembl chr 1:58,776,752...58,786,019

Fpr2l1

formyl peptide receptor 2 like 1

involved_in

PMID:21873635

GO_Central

NCBI chr 1:59,686,519...59,687,550
Ensembl chr 1:59,686,103...59,716,622

Fpr2l2

formyl peptide receptor 2 like 2

involved_in

PMID:21873635

GO_Central

NCBI chr 1:58,997,091...58,998,062
Ensembl chr 1:58,968,268...58,999,984

Fpr2l3

formyl peptide receptor 2 like 3

involved_in

PMID:21873635

GO_Central

NCBI chr 1:59,181,555...59,182,586
Ensembl chr 1:59,173,577...59,200,760

Fpr3

formyl peptide receptor 3

involved_in

PMID:21873635

GO_Central

PMID:15907827 PMID:19135435

NCBI chr 1:58,884,400...58,893,475
Ensembl chr 1:58,845,118...58,893,467

Gpld1

glycosylphosphatidylinositol specific phospholipase D1

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:15907827), (PMID:19135435)

UniProt
Ensembl
RGD

GO_REF:0000024 GO_REF:0000107

NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939

Gpr33-ps1

G protein-coupled receptor 33, pseudogene 1

involved_in

PMID:21873635

GO_Central

NCBI chr 6:69,474,435...69,475,440
Ensembl chr 6:69,474,435...69,475,440

cytosolic pattern recognition receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Alpk1

alpha-kinase 1

involved_in

(PMID:28222186), (PMID:28877472), (PMID:30111836)
PMID:21873635
(MGI:6196443|PMID:30111836)

PMID:28222186 PMID:28877472 PMID:30111836 PMID:21873635

MGI:6196443, RGD:13792537

NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157

Dhx58

DEXH-box helicase 58

involved_in

(PMID:19211564)
PMID:21873635

PMID:19211564 PMID:21873635

NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525

Ifih1

interferon induced with helicase C domain 1

involved_in

PMID:21873635

GO_Central

NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456

Rig1

RNA sensor RIG-1

involved_in

PMID:21873635

GO_Central

NCBI chr 5:55,321,229...55,369,947
Ensembl chr 5:55,321,235...55,370,819

Tifa

TRAF-interacting protein with forkhead-associated domain

involved_in

ISO
ISS
IBA

(PMID:26068852), (PMID:28222186), (PMID:28877472), (PMID:30111836)
GO_REF:0000024
PMID:21873635

PMID:26068852 PMID:28222186 PMID:28877472 PMID:30111836 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841

Fc receptor mediated inhibitory signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Lilrb2

leukocyte immunoglobulin like receptor B2

involved_in

(PMID:9842885)

PMID:9842885

NCBI chr 1:65,326,832...65,334,683
Ensembl chr 1:65,326,832...65,334,679

Lilrb4

leukocyte immunoglobulin like receptor B4

involved_in

(PMID:16493035), (PMID:18420485)

PMID:16493035 PMID:18420485

NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660

LYN proto-oncogene, Src family tyrosine kinase

involved_in

GO_REF:0000024
(MGI:3703139|PMID:16272347)

PMID:16272347

GO_REF:0000024 MGI:3703139

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

Fc receptor mediated stimulatory signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Blk

BLK proto-oncogene, Src family tyrosine kinase

involved_in

PMID:21873635

GO_Central

NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031

Fcer1g

Fc epsilon receptor Ig

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:3029067|PMID:14764707)

PMID:14764707 PMID:21873635

MGI:3029067, RGD:13792537

NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443

LYN proto-oncogene, Src family tyrosine kinase

involved_in

IBA
ISO
ISS

PMID:21873635
(MGI:3703139|PMID:16272347)
GO_REF:0000024

PMID:16272347 PMID:21873635

GO_REF:0000024 MGI:3703139, RGD:13792537

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

Fc receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fcar

Fc alpha receptor

involved_in

(PMID:25339672)

PMID:25339672

NCBI chr 1:69,626,458...69,660,558

Kit

KIT proto-oncogene receptor tyrosine kinase

involved_in

(PMID:20100931)

PMID:20100931

NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652

Pigr

polymeric immunoglobulin receptor

involved_in

(PMID:22022593)
GO_REF:0000107

PMID:22022593

GO_REF:0000107

NCBI chr13:42,298,905...42,326,877
Ensembl chr13:42,298,914...42,326,875

Fc-epsilon receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fcer1a

Fc epsilon receptor Ia

acts_upstream_of_or_within

MGI:2383982 (MGI:86632|PMID:8252632)
(MGI:85068|PMID:9000133)

PMID:8252632 PMID:9000133

MGI:85068 MGI:86632

NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351

Fcer1g

Fc epsilon receptor Ig

involved_in
acts_upstream_of_or_within

PMID:14764707 PMID:16735691

(PMID:16735691)
MGI:2384004 (MGI:3029067|PMID:14764707)
GO_REF:0000108

RGD
GOC

GO_REF:0000108 MGI:3029067

NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443

Fcgr3a

Fc gamma receptor 3A

involved_in

GO_REF:0000108

GO_REF:0000108

NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921

Fer

FER tyrosine kinase

involved_in

ISS
ISO
IBA

GO_REF:0000024
(MGI:2385502|PMID:12192036)
PMID:21873635

PMID:12192036 PMID:21873635

GO_REF:0000024 MGI:2385502, RGD:13792537

NCBI chr 9:103,520,452...103,827,364
Ensembl chr 9:103,520,493...103,821,451

Ms4a2

membrane spanning 4-domains A2

involved_in

GO_REF:0000108

GO_REF:0000108

NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310

Fc-gamma receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd247

Cd247 molecule

involved_in

(PMID:8478617)

PMID:8478617

NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263

Clec4d

C-type lectin domain family 4, member D

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:5525050|PMID:23602766)

PMID:23602766

GO_REF:0000107 MGI:5525050

NCBI chr 4:156,589,591...156,598,969
Ensembl chr 4:156,589,792...156,598,848

Clec4e

C-type lectin domain family 4, member E

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:5525050|PMID:23602766)

PMID:23602766

GO_REF:0000107 MGI:5525050

NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767

Fcer1g

Fc epsilon receptor Ig

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:5525050|PMID:23602766)

PMID:23602766 PMID:21873635

MGI:5525050, RGD:13792537

NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443

Fcgr1a

Fc gamma receptor 1A

acts_upstream_of_or_within

MGI:2679238 (MGI:2679189|PMID:11911823)

PMID:11911823

MGI:2679189

NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994

Fcgr2a

Fc gamma receptor 2A

acts_upstream_of_or_within

MGI:1861924 (MGI:2683749|PMID:9743367)
MGI:1861924 (MGI:2683747|PMID:9834201)

PMID:9743367 PMID:9834201

MGI:2683747 MGI:2683749

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

Fcgr3a

Fc gamma receptor 3A

involved_in

(PMID:23024279)
(PMID:23024279), (PMID:8478617)

PMID:8478617 PMID:23024279

NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921

Fcgrt

Fc gamma receptor and transporter

involved_in

GO_REF:0000108

GO_REF:0000108

NCBI chr 1:95,574,436...95,584,171
Ensembl chr 1:95,567,175...95,584,084

Lck

LCK proto-oncogene, Src family tyrosine kinase

involved_in

GO_REF:0000107
(PMID:8478617)

PMID:8478617

GO_REF:0000107

NCBI chr 5:141,888,319...141,916,992
Ensembl chr 5:141,888,326...141,903,794

Oscar

osteoclast associated Ig-like receptor

acts_upstream_of_or_within

MGI:5301430 (MGI:5297759|PMID:21841309)

PMID:21841309

MGI:5297759

NCBI chr 1:65,607,214...65,615,395
Ensembl chr 1:65,607,410...65,613,758

Fc-gamma receptor signaling pathway involved in phagocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fc gamma receptor 2B

involved_in

(PMID:2142460)

PMID:2142460

NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778

Myo1g

myosin IG

involved_in

(MGI:5586792|PMID:23038771)

PMID:23038771

MGI:5586792

NCBI chr14:81,386,701...81,401,843
Ensembl chr14:81,386,701...81,401,843

helper T cell enhancement of adaptive immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd4

Cd4 molecule

involved_in

(MGI:1933768|PMID:1832488)

PMID:1832488

MGI:1933768

NCBI chr 4:157,668,878...157,695,366

immune response-activating cell surface receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bag6

BAG cochaperone 6

involved_in

(PMID:18852879)
GO_REF:0000107

PMID:18852879

GO_REF:0000107

NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657

Micb

MHC class I polypeptide-related sequence B

involved_in

(PMID:11491531)

PMID:18852879 PMID:21873635

PMID:11491531

NCBI chr 1:78,495,779...78,513,030
Ensembl chr 1:78,495,779...78,512,827

Ncr3

natural cytotoxicity triggering receptor 3

involved_in

IBA
IEA
ISO
ISS

PMID:21873635
GO_REF:0000002
(PMID:18852879)
GO_REF:0000024

InterPro
RGD
UniProt

GO_REF:0000002 GO_REF:0000024, RGD:13792537

NCBI chr20:3,637,242...3,643,748
Ensembl chr20:3,638,240...3,643,799

immune response-activating signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Zc3h12a

zinc finger CCCH type containing 12A

involved_in

GO_REF:0000024
(PMID:19909337)

PMID:19909337

GO_REF:0000024

NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351

immune response-inhibiting cell surface receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Lilrb2

leukocyte immunoglobulin like receptor B2

involved_in

(PMID:14971032), (PMID:20702625)

PMID:14971032 PMID:20702625

NCBI chr 1:65,326,832...65,334,683
Ensembl chr 1:65,326,832...65,334,679

RT1-M3-1

RT1 class Ib, locus M3, gene 1

involved_in

(PMID:20702625)

PMID:20702625

NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117

immune response-inhibiting signal transduction

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd33

CD33 molecule

involved_in

(PMID:10887109)

PMID:10887109

NCBI chr 1:93,935,418...93,940,452
Ensembl chr 1:93,930,971...93,950,149

Il20rb

interleukin 20 receptor subunit beta

acts_upstream_of_or_within

MGI:3830304 (MGI:3827040|PMID:19124723)

PMID:15568026 PMID:21873635

PMID:19124723

MGI:3827040

NCBI chr 8:100,979,085...101,010,829
Ensembl chr 8:100,980,383...101,009,942

immune response-regulating cell surface receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Btla

B and T lymphocyte associated

involved_in
acts_upstream_of_or_within

IEA
ISO
IBA

GO_REF:0000002
MGI:3027713 (MGI:3521631|PMID:15568026)
PMID:21873635

InterPro
RGD

GO_REF:0000002 MGI:3521631, RGD:13792537

NCBI chr11:55,563,683...55,588,187
Ensembl chr11:55,564,899...55,587,181

Cd40

CD40 molecule

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:3051177|PMID:15240714)

PMID:15240714 PMID:21873635

MGI:3051177, RGD:13792537

NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534

Fpr2

formyl peptide receptor 2

involved_in

(PMID:25505240)

PMID:25505240

NCBI chr 1:58,776,592...58,785,227
Ensembl chr 1:58,776,752...58,786,019

LYN proto-oncogene, Src family tyrosine kinase

involved_in

(MGI:894972|PMID:9252121)
GO_REF:0000024

PMID:9252121

GO_REF:0000024 MGI:894972

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

Vav1

vav guanine nucleotide exchange factor 1

IEP

RGD

PMID:1531699

RGD:2306006

NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937

immune response-regulating signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ctsh

cathepsin H

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:16822283)

UniProt
Ensembl
RGD

PMID:16822283

GO_REF:0000024 GO_REF:0000107

NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824

Lat2

linker for activation of T cells family, member 2

involved_in

GO_REF:0000002

GO_REF:0000002

NCBI chr12:22,104,163...22,118,294
Ensembl chr12:22,104,219...22,118,288

innate immune response-activating signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

toll-like receptor 4

RGD

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

lymphocyte costimulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

interleukin 6

RGD

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

MDA-5 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ifih1

interferon induced with helicase C domain 1

involved_in

(PMID:17600090), (PMID:33727702)
PMID:21873635
(PMID:17600090), (PMID:19211564), (PMID:33727702)

PMID:17600090 PMID:19211564 PMID:33727702 PMID:21873635

NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456

Oas3

2'-5'-oligoadenylate synthetase 3

involved_in

(PMID:30078389)
GO_REF:0000107

PMID:30078389

GO_REF:0000107

NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781

MyD88-dependent toll-like receptor 4 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Lrrfip2

LRR binding FLII interacting protein 2

acts_upstream_of_or_within

(MGI:3836337|PMID:19265123)

PMID:19265123

MGI:3836337

NCBI chr 8:111,091,453...111,193,947
Ensembl chr 8:111,091,503...111,193,255

MyD88-dependent toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hmgb1

high mobility group box 1

involved_in

(PMID:14660645)

PMID:14660645

NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565

Hspd1

heat shock protein family D (Hsp60) member 1

involved_in

(PMID:16148103)

PMID:16148103

NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662

Myd88

MYD88, innate immune signal transduction adaptor

acts_upstream_of_or_within
involved_in

PMID:12719478 PMID:12872135 PMID:14764662

MGI:1346060|MGI:2385681 (MGI:2670551|PMID:12872135), (MGI:3028810|PMID:14764662), (MGI:3042099|PMID:12719478)
GO_REF:0000002

RGD
InterPro

GO_REF:0000002 MGI:2670551 MGI:3028810 MGI:3042099

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

Reg3g

regenerating family member 3 gamma

involved_in

GO_REF:0000024
(MGI:3760234|PMID:17635956)

PMID:17635956

GO_REF:0000024 MGI:3760234

NCBI chr 4:110,922,805...110,927,803
Ensembl chr 4:110,924,168...110,926,723

Tlr2

toll-like receptor 2

acts_upstream_of_or_within

MGI:108005 (MGI:3042099|PMID:12719478)

PMID:12719478

MGI:3042099

NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630

Tlr4

toll-like receptor 4

involved_in

GO_REF:0000107
(PMID:20037584)
UniProtKB:Q9EPW9 (MGI:4438693|PMID:20037584)

PMID:20037584

GO_REF:0000107 MGI:4438693

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

Tlr6

toll-like receptor 6

involved_in

UniProtKB:Q9QUK6 (MGI:4438693|PMID:20037584)
(PMID:20037584)

PMID:20037584

MGI:4438693

NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685

Tlr9

toll-like receptor 9

involved_in

UniProtKB:P22366 (MGI:3826712|PMID:18820679)

PMID:18820679

MGI:3826712

NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796

Tnip1

TNFAIP3 interacting protein 1

involved_in

(MGI:5305352|PMID:22011580)

PMID:22011580

MGI:5305352

NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625

MyD88-independent toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Lrrfip2

LRR binding FLII interacting protein 2

acts_upstream_of_or_within

(MGI:3836337|PMID:19265123)

PMID:19265123

MGI:3836337

NCBI chr 8:111,091,453...111,193,947
Ensembl chr 8:111,091,503...111,193,255

Ticam1

TIR domain containing adaptor molecule 1

acts_upstream_of_or_within

MGI:2679794|MGI:3029019 (MGI:2669022|PMID:12855817), (MGI:2670551|PMID:12872135)

PMID:12855817 PMID:12872135

MGI:2669022 MGI:2670551

NCBI chr 9:1,102,559...1,115,573
Ensembl chr 9:1,102,366...1,123,147

Tnip3

TNFAIP3 interacting protein 3

involved_in

(PMID:17088249)

PMID:17088249

NCBI chr 4:94,867,258...94,908,780
Ensembl chr 4:94,811,097...94,907,605

natural killer cell inhibitory signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Clec12b

C-type lectin domain family 12, member B

involved_in

(PMID:17562706)
PMID:21873635

PMID:17562706 PMID:21873635

NCBI chr 4:162,827,462...162,843,821
Ensembl chr 4:162,827,462...162,838,946

Klrc1

killer cell lectin like receptor C1

involved_in

(PMID:9485206)

PMID:9485206

NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425

negative regulation of activated T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Arg1

arginase 1

involved_in

(MGI:5908339|PMID:19360123)

PMID:19360123

MGI:5908339

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

Btn1a1

butyrophilin, subfamily 1, member A1

involved_in

(MGI:4453380|PMID:20208008)

PMID:20208008

MGI:4453380

NCBI chr17:41,654,237...41,663,427
Ensembl chr17:41,654,249...41,664,272

Btn2a2

butyrophilin, subfamily 2, member A2

acts_upstream_of_or_within
involved_in

(MGI:5520006|PMID:23589618)
(MGI:4453380|PMID:20208008)

PMID:20208008 PMID:23589618

MGI:4453380 MGI:5520006

NCBI chr17:41,620,807...41,632,621
Ensembl chr17:41,620,839...41,632,618

Casp3

caspase 3

acts_upstream_of_or_within

MGI:2178778 (MGI:2677082|PMID:12970760)

PMID:12970760

MGI:2677082

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

Cd274

CD274 molecule

involved_in

(PMID:12538684)
(PMID:17489864)

PMID:12538684 PMID:17489864

NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450

Crtam

cytotoxic and regulatory T cell molecule

involved_in

(MGI:3834299|PMID:18329370)

PMID:18329370

MGI:3834299

NCBI chr 8:41,340,117...41,377,343
Ensembl chr 8:41,340,837...41,377,343

Ido1

indoleamine 2,3-dioxygenase 1

acts_upstream_of_or_within

MGI:3505776 (MGI:3776720|PMID:18077788)

PMID:18077788

MGI:3776720

NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730

Laptm5

lysosomal protein transmembrane 5

involved_in

(MGI:3803048|PMID:18619870)

PMID:18619870

MGI:3803048

NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807

Lgals9

galectin 9

involved_in

(PMID:23817958)

PMID:23817958

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

Lilrb4

leukocyte immunoglobulin like receptor B4

involved_in

(PMID:19380766)

PMID:19380766

NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660

Lrrc32

leucine rich repeat containing 32

acts_upstream_of_or_within

(MGI:3807624|PMID:18628982)

PMID:18628982

MGI:3807624

NCBI chr 1:152,785,709...152,802,997
Ensembl chr 1:152,786,511...152,798,373

Mir181c

microRNA 181c

acts_upstream_of

(PMID:21112091)

PMID:21112091

NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628

Pdcd1lg2

programmed cell death 1 ligand 2

involved_in

(PMID:12538684)

PMID:12538684

NCBI chr 1:227,158,941...227,223,938
Ensembl chr 1:227,158,941...227,223,938

Prkar1a

protein kinase cAMP-dependent type I regulatory subunit alpha

involved_in

(PMID:17911601)

PMID:17911601

NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041

Prnp

prion protein

involved_in

(MGI:4943618|PMID:20145049)

PMID:20145049

MGI:4943618

NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937

Rc3h1

ring finger and CCCH-type domains 1

involved_in

(MGI:5284769|PMID:18172933)

PMID:18172933

MGI:5284769

NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839

Scrib

scribble planar cell polarity protein

involved_in

(MGI:3834299|PMID:18329370)

PMID:18329370

MGI:3834299

NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331

negative regulation of activation of membrane attack complex

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd59

CD59 molecule

acts_upstream_of_or_within
involved_in

IDA
ISO
IBA

(MGI:1888643|PMID:10946279), (MGI:2148385|PMID:11471050)
PMID:21873635

PMID:10946279 PMID:11471050 PMID:15843577 PMID:21873635

MGI:1888643 MGI:2148385, RGD:1600482, RGD:13792537

NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847

negative regulation of activation-induced cell death of T cells

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fadd

Fas associated via death domain

involved_in

GO_REF:0000024
(MGI:5291865|PMID:21876153)

PMID:21876153

GO_REF:0000024 MGI:5291865

NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653

Gpam

glycerol-3-phosphate acyltransferase, mitochondrial

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2669956 (MGI:3826295|PMID:18971390)

PMID:18971390

GO_REF:0000107 MGI:3826295

NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639

Tnfrsf4

TNF receptor superfamily member 4

involved_in

(MGI:2150820|PMID:11567634)

PMID:11567634

MGI:2150820

NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599

Tsc22d3

TSC22 domain family, member 3

acts_upstream_of_or_within

(MGI:1101744|PMID:9430225)

PMID:9430225

MGI:1101744

NCBI chr X:104,217,898...104,277,935
Ensembl chr X:104,217,925...104,276,861

negative regulation of acute inflammatory response to antigenic stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adcyap1

adenylate cyclase activating polypeptide 1

RGD

PMID:17698245

RGD:2325282

NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773

Fc gamma receptor 2B

acts_upstream_of_or_within

MGI:1857166 (MGI:3608295|PMID:12385742)

PMID:12385742

MGI:3608295

NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778

neuropeptide Y

RGD

NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495

Npy5r

neuropeptide Y receptor Y5

RGD

PMID:18805447

RGD:10448932

NCBI chr16:23,055,427...23,063,384
Ensembl chr16:23,055,427...23,063,382

Selenos

selenoprotein S

involved_in

(PMID:18675776)
GO_REF:0000107

PMID:18675776

GO_REF:0000107

NCBI chr 1:119,659,779...119,669,546
Ensembl chr 1:119,659,751...119,669,833

negative regulation of adaptive immune memory response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd160

CD160 molecule

involved_in

(PMID:18193050)

PMID:18193050

NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834

Tnfrsf14

TNF receptor superfamily member 14

involved_in

(PMID:18193050)

PMID:18193050

NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703

negative regulation of adaptive immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Alox15

arachidonate 15-lipoxygenase

involved_in

GO_REF:0000024
(MGI:5436199|PMID:22503541)

PMID:22503541

GO_REF:0000024 MGI:5436199

NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874

Samsn1

SAM domain, SH3 domain and nuclear localization signals, 1

involved_in

(MGI:4437539|PMID:19923443)

PMID:19923443

MGI:4437539

NCBI chr11:14,484,523...14,534,900
Ensembl chr11:14,483,893...14,534,900

Trim27

tripartite motif-containing 27

involved_in

(PMID:22128329)

PMID:22128329

NCBI chr17:43,538,282...43,550,633
Ensembl chr17:43,538,285...43,550,643

negative regulation of alpha-beta T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adora2a

adenosine A2a receptor

acts_upstream_of_or_within

(MGI:3822045|PMID:10069416)

PMID:10069416

MGI:3822045

NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386

Vsir

V-set immunoregulatory receptor

involved_in

PMID:21873635

GO_Central

NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878

negative regulation of alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gli3

GLI family zinc finger 3

involved_in

(MGI:4355451|PMID:19667090)

PMID:19667090

MGI:4355451

NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712

Ihh

Indian hedgehog signaling molecule

involved_in

(MGI:3836494|PMID:19109233)

PMID:19109233

MGI:3836494

NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532

Shh

sonic hedgehog signaling molecule

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:1888832|PMID:10981962)

PMID:10981962

GO_REF:0000107 MGI:1888832

NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170

negative regulation of alpha-beta T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Btla

B and T lymphocyte associated

acts_upstream_of_or_within

MGI:3027713 (MGI:3521631|PMID:15568026)

PMID:15568026

MGI:3521631

NCBI chr11:55,563,683...55,588,187
Ensembl chr11:55,564,899...55,587,181

Cblb

Cbl proto-oncogene B

acts_upstream_of_or_within

MGI:2180572 (MGI:3038342|PMID:14973438)

MGI:3038342

NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839

Clec4g

C-type lectin domain family 4, member G

acts_upstream_of_or_within

MGI:5510586 (MGI:5475030|PMID:23487419)

PMID:23487419

MGI:5475030

NCBI chr12:1,780,370...1,785,027
Ensembl chr12:1,780,371...1,784,985

Foxp3

forkhead box P3

acts_upstream_of_or_within

MGI:1857034 (MGI:3692513|PMID:16945588)

PMID:16945588

MGI:3692513

NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838

Itch

itchy E3 ubiquitin protein ligase

acts_upstream_of_or_within

MGI:1856404 (MGI:3038342|PMID:14973438)

MGI:3038342

NCBI chr 3:143,642,348...143,733,745
Ensembl chr 3:143,645,637...143,733,543

Tnfrsf14

TNF receptor superfamily member 14

acts_upstream_of_or_within
involved_in

(MGI:3521631|PMID:15568026)
PMID:21873635

PMID:15568026 PMID:21873635

MGI:3521631, RGD:13792537

NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703

negative regulation of antibacterial peptide production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Spink5

serine peptidase inhibitor, Kazal type 5

involved_in

(MGI:3770082|PMID:17012259)

PMID:17012259

MGI:3770082

NCBI chr18:36,264,452...36,333,143
Ensembl chr18:36,264,452...36,332,185

negative regulation of antifungal innate immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fam3a

FAM3 metabolism regulating signaling molecule A

involved_in

(PMID:18212107)

PMID:18212107

NCBI chr X:152,166,716...152,175,327
Ensembl chr X:152,165,535...152,175,362

Usp15

ubiquitin specific peptidase 15

involved_in

IEA
ISO
ISS

GO_REF:0000107
(PMID:33093067)
GO_REF:0000024

Ensembl
RGD
UniProt

PMID:33093067

GO_REF:0000024 GO_REF:0000107

NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721

negative regulation of antigen processing and presentation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Lilrb2

leukocyte immunoglobulin like receptor B2

involved_in

(PMID:19124746)

PMID:19124746

NCBI chr 1:65,326,832...65,334,683
Ensembl chr 1:65,326,832...65,334,679

negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hfe

homeostatic iron regulator

involved_in

UniProtKB:P04439 (PMID:24643698)

PMID:24643698

NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502

negative regulation of antigen processing and presentation of peptide antigen via MHC class I

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Tapbpl

TAP binding protein-like

involved_in

(PMID:23401559)

PMID:23401559

NCBI chr 4:158,021,454...158,028,905

negative regulation of antigen processing and presentation of peptide antigen via MHC class II

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RT1-DOa

RT1 class II, locus DOa

involved_in

(PMID:22733780)

PMID:22733780

NCBI chr20:4,753,587...4,756,590
Ensembl chr20:4,753,598...4,756,577

RT1-DOb

RT1 class II, locus DOb

involved_in

(PMID:22733780)

PMID:22733780

NCBI chr20:4,619,599...4,625,627
Ensembl chr20:4,619,816...4,625,667

negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Thbs1

thrombospondin 1

involved_in

(PMID:16882710)

PMID:16882710

NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440

negative regulation of B cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bank1

B-cell scaffold protein with ankyrin repeats 1

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:88336 (MGI:3665389|PMID:16546095)

PMID:16546095 PMID:21873635

MGI:3665389, RGD:13792537

NCBI chr 2:224,530,475...224,800,420
Ensembl chr 2:224,530,475...224,800,405

Btk

Bruton tyrosine kinase

RGD

PMID:25545336

RGD:151665128

NCBI chr X:97,722,796...97,762,315
Ensembl chr X:97,722,802...97,761,853

Fas

Fas cell surface death receptor

acts_upstream_of_or_within

MGI:1856334 (MGI:55958|PMID:6610701)

PMID:6610701

MGI:55958

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

Foxj1

forkhead box J1

involved_in

(MGI:3589323|PMID:16002694)

PMID:16002694

MGI:3589323

NCBI chr10:101,566,299...101,570,249
Ensembl chr10:101,566,304...101,570,237

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

MGI:2386884 (MGI:1354084|PMID:10704460)

PMID:10704460

MGI:1354084

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

Laptm5

lysosomal protein transmembrane 5

involved_in

(MGI:4460047|PMID:20519653)

PMID:20519653

MGI:4460047

NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807

Mir185

microRNA 185

acts_upstream_of

(PMID:24803541)

PMID:24803541

NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795

Samsn1

SAM domain, SH3 domain and nuclear localization signals, 1

involved_in

PMID:21873635
(MGI:4437539|PMID:19923443)

PMID:19923443 PMID:21873635

MGI:4437539, RGD:13792537

NCBI chr11:14,484,523...14,534,900
Ensembl chr11:14,483,893...14,534,900

Tbc1d10c

TBC1 domain family, member 10C

acts_upstream_of_or_within

MGI:1932389|MGI:5578034 (MGI:5576870|PMID:23109291)

PMID:23109291

MGI:5576870

NCBI chr 1:201,476,258...201,484,876
Ensembl chr 1:201,477,157...201,564,920

Tnfaip3

TNF alpha induced protein 3

involved_in

(MGI:4946158|PMID:21088135)

PMID:21088135

MGI:4946158

NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282

negative regulation of B cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Flt3

Fms related receptor tyrosine kinase 3

acts_upstream_of_or_within

(MGI:3623701|PMID:16618805)

PMID:16618805

MGI:3623701

NCBI chr12:7,623,658...7,699,474
Ensembl chr12:7,623,930...7,699,474

Hmgb3

high mobility group box 3

acts_upstream_of_or_within

(MGI:2670545|PMID:12714519)

PMID:12714519

MGI:2670545

NCBI chr X:149,296,309...149,301,294
Ensembl chr X:149,296,375...149,301,292

Id2

inhibitor of DNA binding 2

acts_upstream_of_or_within

MGI:2384134 (MGI:3805135|PMID:18523151)

PMID:18523151

MGI:3805135

NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400

Sfrp1

secreted frizzled-related protein 1

involved_in

(PMID:18941195)
(MGI:3814493|PMID:18941195)
GO_REF:0000107

PMID:18941195

GO_REF:0000107 MGI:3814493

NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286

negative regulation of B cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Atm

ATM serine/threonine kinase

involved_in

(PMID:17875758)

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

Blk

BLK proto-oncogene, Src family tyrosine kinase

involved_in

PMID:21873635

GO_Central

NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031

Btk

Bruton tyrosine kinase

acts_upstream_of_or_within

MGI:1856317 (MGI:65977|PMID:7680896)

PMID:7680896

MGI:65977

NCBI chr X:97,722,796...97,762,315
Ensembl chr X:97,722,802...97,761,853

Btla

B and T lymphocyte associated

acts_upstream_of_or_within

MGI:3027713 (MGI:2665193|PMID:12796776)

PMID:12796776

MGI:2665193

NCBI chr11:55,563,683...55,588,187
Ensembl chr11:55,564,899...55,587,181

Casp3

caspase 3

acts_upstream_of_or_within

MGI:2178778 (MGI:2677082|PMID:12970760)

PMID:12970760

MGI:2677082

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

Cd24

CD24 molecule

acts_upstream_of_or_within

(MGI:3757615|PMID:8920854)

PMID:8920854

MGI:3757615

NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662

Cd300a molecule

involved_in

(PMID:21482706)

PMID:21482706

NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674

Cdkn2a

cyclin-dependent kinase inhibitor 2A

involved_in

(MGI:3615850|PMID:15964995)

PMID:15964995

MGI:3615850

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

Ctla4

cytotoxic T-lymphocyte-associated protein 4

involved_in

(PMID:17875758)

NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963

Fc gamma receptor 2B

acts_upstream_of_or_within

MGI:1857166 (MGI:3608295|PMID:12385742), (MGI:78617|PMID:8552190)

PMID:8552190 PMID:12385742

MGI:3608295 MGI:78617

NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778

Il10

interleukin 10

involved_in
acts_upstream_of_or_within

GO_REF:0000024
(PMID:9184696)

PMID:9184696

GO_REF:0000024

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

inositol polyphosphate-5-phosphatase D

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2386884 (MGI:1354084|PMID:10704460)

PMID:10704460

GO_REF:0000107 MGI:1354084

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

LYN proto-oncogene, Src family tyrosine kinase

involved_in

PMID:21873635
(MGI:894972|PMID:9252121)

PMID:9252121 PMID:21873635

MGI:894972, RGD:13792537

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

Mir185

microRNA 185

acts_upstream_of

(PMID:24803541)

PMID:24803541

NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795

Mnda

myeloid cell nuclear differentiation antigen

involved_in

(PMID:17875758)

NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201

Pawr

pro-apoptotic WT1 regulator

acts_upstream_of_or_within

MGI:2678021 (MGI:2675524|PMID:12970181)

PMID:12970181

MGI:2675524

NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028

Pkn1

protein kinase N1

acts_upstream_of_or_within

MGI:5475202 (MGI:5467878|PMID:23223530)

PMID:23223530

MGI:5467878

NCBI chr19:24,442,130...24,470,107
Ensembl chr19:24,442,122...24,470,107

Prdm1

PR/SET domain 1

acts_upstream_of_or_within

(MGI:3826899|PMID:18845144)

PMID:18845144

MGI:3826899

NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488

Pten

phosphatase and tensin homolog

acts_upstream_of_or_within

MGI:1857936 (MGI:3586939|PMID:16027169)

PMID:16027169

MGI:3586939

NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838

Rc3h1

ring finger and CCCH-type domains 1

involved_in

(MGI:5284769|PMID:18172933)

PMID:18172933

MGI:5284769

NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839

Tnfrsf13b

TNF receptor superfamily member 13B

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:3052983 (MGI:3051152|PMID:15240667)

PMID:15240667 PMID:21873635

MGI:3051152, RGD:13792537

NCBI chr10:45,801,860...45,824,932
Ensembl chr10:45,801,860...45,822,987

Tnfrsf21

TNF receptor superfamily member 21

involved_in

IBA
ISO
ISS

PMID:21873635
(MGI:3628730|PMID:12515813)
GO_REF:0000024

PMID:12515813 PMID:21873635

GO_REF:0000024 MGI:3628730, RGD:13792537

NCBI chr 9:17,879,156...17,954,085
Ensembl chr 9:17,879,156...17,954,085

Tsc2

TSC complex subunit 2

acts_upstream_of_or_within

MGI:109583 (MGI:3586939|PMID:16027169)

PMID:16027169

MGI:3586939

NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951

Tyrobp

transmembrane immune signaling adaptor Tyrobp

involved_in

(PMID:21727189)
(MGI:5295549|PMID:21727189)
PMID:21873635

PMID:21727189 PMID:21873635

MGI:5295549, RGD:13792537

NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848

negative regulation of B cell receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd22

CD22 molecule

involved_in

PMID:21873635
(PMID:24169826), (PMID:26017478)

PMID:24169826 PMID:26017478 PMID:21873635

NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322

Cd300a molecule

involved_in

(PMID:21482706)

PMID:21482706

NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674

Fc gamma receptor 2B

involved_in

(PMID:24169826)

PMID:24169826

NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778

Fcrl5

Fc receptor-like 5

acts_upstream_of_or_within

MGI:96055|MGI:96892 (MGI:5471851|PMID:23509253)

PMID:23509253

MGI:5471851

NCBI chr 2:172,881,763...172,912,912
Ensembl chr 2:172,881,448...172,913,148

Gps2

G protein pathway suppressor 2

involved_in

(MGI:5896692|PMID:28039360)

PMID:28039360

MGI:5896692

NCBI chr10:54,637,360...54,640,542
Ensembl chr10:54,637,455...54,640,650

Lpxn

leupaxin

involved_in

PMID:21873635
(MGI:3722965|PMID:17640867)
(PMID:17640867)

PMID:17640867 PMID:21873635

MGI:3722965, RGD:13792537

NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084

Mir34a

microRNA 34a

involved_in

(PMID:30111844)

PMID:30111844

NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103

Plcl2

phospholipase C-like 2

acts_upstream_of_or_within

MGI:2679632 (MGI:2677607|PMID:14517301)

PMID:14517301

MGI:2677607

NCBI chr 9:3,292,564...3,477,009
Ensembl chr 9:3,292,695...3,477,009

negative regulation of CD4-positive, alpha-beta T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Tarm1

T cell-interacting, activating receptor on myeloid cells 1

involved_in

(PMID:26311901)

PMID:26311901

NCBI chr 1:65,666,742...65,682,402
Ensembl chr 1:65,671,902...65,679,626

Twsg1

twisted gastrulation BMP signaling modulator 1

involved_in

(PMID:17164348)

PMID:17164348

NCBI chr 9:105,533,116...105,567,525
Ensembl chr 9:105,533,136...105,567,479

negative regulation of CD4-positive, alpha-beta T cell costimulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd160

CD160 molecule

involved_in

(PMID:18193050)

PMID:18193050

NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834

negative regulation of CD4-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cbfb

core-binding factor subunit beta

involved_in

(MGI:3772948|PMID:18258917)

PMID:18258917

MGI:3772948

NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751

Hmgb1

high mobility group box 1

involved_in

(PMID:22473704)

PMID:22473704

NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565

Runx1

RUNX family transcription factor 1

involved_in

GO_REF:0000024
(MGI:3772948|PMID:18258917)

PMID:18258917

GO_REF:0000024 MGI:3772948

NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542

Runx3

RUNX family transcription factor 3

involved_in

(MGI:3772948|PMID:18258917)

PMID:18258917

MGI:3772948

NCBI chr 5:147,393,926...147,419,161
Ensembl chr 5:147,360,994...147,419,156

negative regulation of CD4-positive, alpha-beta T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Arg2

arginase 2

involved_in

GO_REF:0000107
(MGI:5908533|PMID:25009204)

PMID:25009204

GO_REF:0000107 MGI:5908533

NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378

Cblb

Cbl proto-oncogene B

acts_upstream_of_or_within
involved_in

MGI:2180572 (MGI:3038342|PMID:14973438)
GO_REF:0000107

GO_REF:0000107 MGI:3038342

NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839

Cd274

CD274 molecule

involved_in

(PMID:24691993)

PMID:24691993

NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450

Cd44

CD44 molecule (Indian blood group)

involved_in

(MGI:5688819|PMID:25065622)

PMID:25065622

MGI:5688819

NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620

Foxp3

forkhead box P3

acts_upstream_of_or_within

(MGI:3697020|PMID:17028180)

PMID:17028180

MGI:3697020

NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838

Itch

itchy E3 ubiquitin protein ligase

acts_upstream_of_or_within

MGI:1856404 (MGI:3038342|PMID:14973438)

MGI:3038342

NCBI chr 3:143,642,348...143,733,745
Ensembl chr 3:143,645,637...143,733,543

Lgals5

galectin 5

involved_in

PMID:21873635

GO_Central

NCBI chr10:63,853,949...63,857,198
Ensembl chr10:63,853,935...63,857,153

Lgals7

galectin 7

involved_in

PMID:21873635

GO_Central

NCBI chr 1:84,148,612...84,152,016
Ensembl chr 1:84,150,252...84,152,015

Lgals9

galectin 9

involved_in

(PMID:20209097)
(MGI:5688819|PMID:25065622)
PMID:21873635

PMID:20209097 PMID:25065622 PMID:21873635

MGI:5688819, RGD:13792537

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

Ndfip1

Nedd4 family interacting protein 1

acts_upstream_of_or_within

MGI:3695433 (MGI:3694584|PMID:17137798)

PMID:17137798

MGI:3694584

NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311

Tarm1

T cell-interacting, activating receptor on myeloid cells 1

involved_in

(MGI:5908526|PMID:26311901)

PMID:26311901

MGI:5908526

NCBI chr 1:65,666,742...65,682,402
Ensembl chr 1:65,671,902...65,679,626

Tnfrsf14

TNF receptor superfamily member 14

acts_upstream_of_or_within

(MGI:3521631|PMID:15568026)

PMID:15568026

MGI:3521631

NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703

Twsg1

twisted gastrulation BMP signaling modulator 1

involved_in

(PMID:17164348)

PMID:17164348

NCBI chr 9:105,533,116...105,567,525
Ensembl chr 9:105,533,136...105,567,479

Vsir

V-set immunoregulatory receptor

involved_in
acts_upstream_of_or_within

(PMID:24691993)
(MGI:5292805|PMID:21383057)

PMID:21383057 PMID:24691993

MGI:5292805

NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878

Xcl1

X-C motif chemokine ligand 1

involved_in

(PMID:10887101)

PMID:10887101

NCBI chr13:77,248,865...77,252,308
Ensembl chr13:77,248,717...77,252,329

negative regulation of CD8-positive, alpha-beta T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd274

CD274 molecule

involved_in

(PMID:28813410), (PMID:28813417)

PMID:28813410 PMID:28813417

NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450

Hfe

homeostatic iron regulator

involved_in

UniProtKB:P04439 (PMID:24643698)

PMID:24643698

NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502

negative regulation of CD8-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Slc4a2

solute carrier family 4 member 2

involved_in
acts_upstream_of_or_within

GO_REF:0000024
(MGI:6840447|PMID:24515893)
(PMID:24515893)

PMID:24515893

GO_REF:0000024 MGI:6840447

NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965

Socs1

suppressor of cytokine signaling 1

involved_in

IEA
ISO
ISS

GO_REF:0000107
(MGI:6140589|PMID:24880459)
GO_REF:0000024

Ensembl
RGD
UniProt

PMID:24880459

GO_REF:0000024 GO_REF:0000107 MGI:6140589

NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383

Zbtb7b

zinc finger and BTB domain containing 7B

involved_in

(MGI:5446998|PMID:22730529), (MGI:6140589|PMID:24880459)

PMID:22730529 PMID:24880459

MGI:5446998 MGI:6140589

NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236

negative regulation of CD8-positive, alpha-beta T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Slc4a2

solute carrier family 4 member 2

involved_in
acts_upstream_of_or_within

GO_REF:0000024
(MGI:6840447|PMID:24515893)
(PMID:24515893)

PMID:24515893

GO_REF:0000024 MGI:6840447

NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965

Vsir

V-set immunoregulatory receptor

involved_in

(PMID:24691993)

PMID:24691993

NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878

negative regulation of cellular extravasation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abr

ABR activator of RhoGEF and GTPase

involved_in

(MGI:5475443|PMID:23152932)

PMID:23152932

MGI:5475443

NCBI chr10:61,262,516...61,461,331
Ensembl chr10:61,262,516...61,461,505

Bcr

BCR activator of RhoGEF and GTPase

involved_in

(MGI:5475443|PMID:23152932)

PMID:23152932

MGI:5475443

NCBI chr20:13,471,679...13,596,497
Ensembl chr20:13,471,668...13,597,016

Il27ra

interleukin 27 receptor subunit alpha

involved_in

UniProtKB:P35951 (MGI:5581894|PMID:22927332)

PMID:22927332

MGI:5581894

NCBI chr19:24,109,698...24,121,977
Ensembl chr19:24,109,972...24,121,938

Mir146a

microRNA 146a

acts_upstream_of

(PMID:31926946)

PMID:31926946

NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610

negative regulation of chronic inflammatory response to antigenic stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Il10

interleukin 10

acts_upstream_of_or_within

MGI:1857199 (MGI:3774790|PMID:12452830)

PMID:12452830

MGI:3774790

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

negative regulation of complement activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd55

CD55 molecule (Cromer blood group)

involved_in

IDA
ISO

(PMID:28657829), (PMID:6211481)

PMID:6211481 PMID:28657829 PMID:10929073

RGD:2326180

NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831

Cd59

CD59 molecule

acts_upstream_of_or_within

(MGI:1888643|PMID:10946279)

PMID:10946279

MGI:1888643

NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847

complement C3b/C4b receptor 1 like

acts_upstream_of_or_within

IMP
ISO

MGI:2158683 (MGI:1351571|PMID:10642554)

PMID:10642554 PMID:11861390

MGI:1351571, RGD:625470

NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445

MBL associated serine protease 1

involved_in

(PMID:11485744)

PMID:11485744

NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974

negative regulation of complement activation, alternative pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd46

CD46 molecule

involved_in

(PMID:9029106)

PMID:9029106

NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445

Susd4

sushi domain containing 4

involved_in

(PMID:23482636)
PMID:21873635

PMID:23482636 PMID:21873635

NCBI chr13:94,455,180...94,577,773
Ensembl chr13:94,455,165...94,577,750

Vsig4

V-set and immunoglobulin domain containing 4

involved_in

PMID:21873635
UniProtKB:P01024 (PMID:17051150)

PMID:17051150 PMID:21873635

NCBI chr X:61,144,926...61,170,212
Ensembl chr X:61,144,928...61,170,212

negative regulation of complement activation, classical pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

C4bpa

complement component 4 binding protein, alpha

involved_in

ISO
IBA
IEA

(PMID:22333221)
PMID:21873635
GO_REF:0000107

PMID:22333221 PMID:21873635

GO_REF:0000107, RGD:13792537

NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205

C4bpb

complement component 4 binding protein, beta

involved_in

(PMID:22333221)

PMID:22333221

NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817

Cd46

CD46 molecule

involved_in

(PMID:9029106)
PMID:21873635

PMID:9029106 PMID:21873635

NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445

Cd55

CD55 molecule (Cromer blood group)

involved_in

PMID:21873635

GO_Central

NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831

complement C3b/C4b receptor 1 like

involved_in

PMID:21873635

GO_Central

NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445

Cr2

complement C3d receptor 2

involved_in

PMID:21873635

GO_Central

NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235

RGD1559810

similar to hypothetical protein

involved_in

PMID:21873635

GO_Central

NCBI chr20:33,996,404...33,997,405
Ensembl chr20:33,996,224...33,997,432

Susd4

sushi domain containing 4

involved_in

PMID:21873635
(PMID:23482636)

PMID:23482636 PMID:21873635

NCBI chr13:94,455,180...94,577,773
Ensembl chr13:94,455,165...94,577,750

Zp3r

zona pellucida 3 receptor

involved_in

PMID:21873635

GO_Central

NCBI chr13:42,019,998...42,064,836
Ensembl chr13:42,020,018...42,064,812

negative regulation of complement activation, lectin pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

A2m

alpha-2-macroglobulin

involved_in

(PMID:12538697)

PMID:12538697

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

Serping1

serpin family G member 1

involved_in

GO_REF:0000024
(PMID:10946292)

PMID:10946292

GO_REF:0000024

NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034

negative regulation of cytokine production involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Angpt1

angiopoietin 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:4437182|PMID:20060382)

PMID:20060382

GO_REF:0000107 MGI:4437182

NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067

Apoa1

apolipoprotein A1

involved_in

(PMID:12458630)
GO_REF:0000107

PMID:12458630

GO_REF:0000107

NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035

Apoa2

apolipoprotein A2

involved_in

(PMID:12458630)

PMID:12458630

NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355

Il10

interleukin 10

involved_in

GO_REF:0000024
(PMID:10443688)

PMID:10443688

GO_REF:0000024

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

Tnf

tumor necrosis factor

involved_in

(PMID:10443688)

PMID:10443688

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

negative regulation of cytotoxic T cell degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ceacam1

CEA cell adhesion molecule 1

involved_in

(PMID:18424730)
GO_REF:0000024

PMID:18424730

GO_REF:0000024

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

Nckap1l

NCK associated protein 1 like

involved_in

(PMID:32647003)

PMID:32647003

NCBI chr 7:134,577,443...134,622,934
Ensembl chr 7:134,577,482...134,622,934

negative regulation of cytotoxic T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Lilrb4

leukocyte immunoglobulin like receptor B4

involved_in

(PMID:16493035)

PMID:16493035

NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660

negative regulation of dendritic cell antigen processing and presentation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd68

Cd68 molecule

involved_in

(MGI:5285055|PMID:21572087)

PMID:21572087

MGI:5285055

NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697

Fgl2

fibrinogen-like 2

acts_upstream_of_or_within

MGI:3582343 (MGI:6188369|PMID:29341118)

PMID:29341118

MGI:6188369

NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207

Thbs1

thrombospondin 1

involved_in

(PMID:16882710)

PMID:16882710

NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440

negative regulation of dendritic cell chemotaxis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Slamf8

SLAM family member 8

acts_upstream_of_or_within

MGI:5442794 (MGI:5752697|PMID:25799045)

PMID:25799045

MGI:5752697

NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211

negative regulation of dendritic cell cytokine production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Jak3

Janus kinase 3

involved_in

GO_REF:0000024
(MGI:3719947|PMID:16020505)

BHF-UCL
RGD

PMID:16020505

GO_REF:0000024 MGI:3719947

NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536

negative regulation of dendritic cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RT1-M3-1

RT1 class Ib, locus M3, gene 1

involved_in

(PMID:20702625)

PMID:20702625

NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117

Tmem176a

transmembrane protein 176A

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:4835631|PMID:20501748)

PMID:20501748 PMID:21873635

MGI:4835631, RGD:13792537

NCBI chr 4:77,774,940...77,778,620
Ensembl chr 4:77,774,843...77,778,620

Tmem176b

transmembrane protein 176B

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:4835631|PMID:20501748)

PMID:20501748 PMID:21873635

MGI:4835631, RGD:13792537

NCBI chr 4:77,766,928...77,774,740
Ensembl chr 4:77,766,928...77,774,384

Zbtb46

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

MGI:5320483 (MGI:5320487|PMID:22615127)

PMID:22615127

MGI:5320487

NCBI chr 3:168,497,294...168,567,799
Ensembl chr 3:168,499,583...168,568,782

negative regulation of eosinophil activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd300a molecule

involved_in

(PMID:16254138)

PMID:16254138

NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674

negative regulation of eosinophil degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ccr2

C-C motif chemokine receptor 2

involved_in

(MGI:3699670|PMID:14662900)
GO_REF:0000024

RGD
BHF-UCL

PMID:14662900

GO_REF:0000024 MGI:3699670

NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100

negative regulation of eosinophil extravasation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ptger4

prostaglandin E receptor 4

involved_in

ISS
IEA
ISO

GO_REF:0000024
GO_REF:0000107
(PMID:21681739)

UniProt
Ensembl
RGD

PMID:21681739

GO_REF:0000024 GO_REF:0000107

NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670

negative regulation of eosinophil migration

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd300a molecule

involved_in

(PMID:16254138)

PMID:16254138

NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674

negative regulation of erythrocyte clearance

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd24

CD24 molecule

acts_upstream_of_or_within

MGI:2179996 (MGI:2179980|PMID:9028339)

PMID:9028339

MGI:2179980

NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662

Ypel4

yippee-like 4

acts_upstream_of_or_within

MGI:4456736 (MGI:6754953|PMID:34354145)

PMID:34354145

MGI:6754953

NCBI chr 3:69,815,373...69,820,708
Ensembl chr 3:69,816,175...69,820,707

negative regulation of erythrocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gas2l1

growth arrest-specific 2 like 1

involved_in

(PMID:19375645)

PMID:19375645 PMID:19375645

RGD:12790653

NCBI chr14:79,951,702...79,961,830
Ensembl chr14:79,950,555...79,961,438

Hoxa5

homeo box A5

involved_in

(PMID:10397719)

PMID:10397719

NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234

Hspa9

heat shock protein family A (Hsp70) member 9

involved_in

IEA
ISS
ISO

GO_REF:0000107
GO_REF:0000024
(PMID:21123823)

Ensembl
UniProt
RGD

PMID:21123823

GO_REF:0000024 GO_REF:0000107

NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292

Klf13

KLF transcription factor 13

involved_in

(MGI:3796470|PMID:18285334)

PMID:18285334

MGI:3796470

NCBI chr 1:117,505,857...117,536,626
Ensembl chr 1:117,503,602...117,551,227

Ldb1

LIM domain binding 1

involved_in

(MGI:3700453|PMID:9391090)

PMID:9391090

MGI:3700453

NCBI chr 1:244,864,168...244,890,007
Ensembl chr 1:244,877,173...244,890,013

Lmo2

LIM domain only 2

involved_in

(MGI:3700453|PMID:9391090)

PMID:9391090

MGI:3700453

NCBI chr 3:90,355,234...90,377,970
Ensembl chr 3:90,365,883...90,377,953

Mafb

MAF bZIP transcription factor B

involved_in

(PMID:8620536)

PMID:8620536

NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031

Stat5a

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

MGI:103035 (MGI:1332382|PMID:10072077)

PMID:10072077

MGI:1332382

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

Stat5b

signal transducer and activator of transcription 5B

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:103036 (MGI:1332382|PMID:10072077)

PMID:10072077

GO_REF:0000107 MGI:1332382

NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668

Ypel4

yippee-like 4

acts_upstream_of_or_within

MGI:4456736 (MGI:6754953|PMID:34354145)

PMID:34354145

MGI:6754953

NCBI chr 3:69,815,373...69,820,708
Ensembl chr 3:69,816,175...69,820,707

Zfp36

zinc finger protein 36

involved_in

GO_REF:0000024
(PMID:20702587)

PMID:20702587

GO_REF:0000024

NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564

Zfp36l1

zinc finger protein 36, C3H type-like 1

involved_in

GO_REF:0000024
(PMID:20702587)

PMID:20702587

GO_REF:0000024

NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748

negative regulation of establishment of T cell polarity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ripor2

RHO family interacting cell polarization regulator 2

involved_in

(PMID:23241886)
GO_REF:0000024

PMID:23241886

GO_REF:0000024

NCBI chr17:40,323,867...40,547,482
Ensembl chr17:40,323,867...40,548,092

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Appl1

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

involved_in

(MGI:6271154|PMID:25568335)

PMID:25568335

MGI:6271154

NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692

Cd47

Cd47 molecule

involved_in

PMID:21401967

ARUK-UCL

PMID:21401967

RGD:13792533

NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425

Pten

phosphatase and tensin homolog

RGD

PMID:18056380

RGD:2292524

NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838

negative regulation of germinal center formation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Foxj1

forkhead box J1

involved_in

(MGI:3589323|PMID:16002694)

PMID:16002694

MGI:3589323

NCBI chr10:101,566,299...101,570,249
Ensembl chr10:101,566,304...101,570,237

Rc3h1

ring finger and CCCH-type domains 1

involved_in

(MGI:5284769|PMID:18172933)

PMID:18172933

MGI:5284769

NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839

negative regulation of granulocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adipoq

adiponectin, C1Q and collagen domain containing

involved_in

(PMID:10961870)
GO_REF:0000024

PMID:10961870

GO_REF:0000024

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

C1qc

complement C1q C chain

involved_in

(PMID:10961870)
GO_REF:0000107

PMID:10961870

GO_REF:0000107

NCBI chr 5:149,127,424...149,130,732
Ensembl chr 5:149,127,415...149,131,017

Ceacam1

CEA cell adhesion molecule 1

involved_in

GO_REF:0000024
(MGI:4837548|PMID:21029969)

PMID:21029969

GO_REF:0000024 MGI:4837548

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

Cul4a

cullin 4A

acts_upstream_of_or_within

(MGI:3691926|PMID:12393421)

PMID:12393421

MGI:3691926

NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

MGI:2386884 (MGI:1266928|PMID:9620849)

PMID:9620849

MGI:1266928

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

Prdm16

PR/SET domain 16

involved_in

(PMID:12816872)

PMID:12816872

NCBI chr 5:164,879,864...165,203,986
Ensembl chr 5:164,880,587...165,203,601

Rara

retinoic acid receptor, alpha

involved_in

(PMID:19917671)

PMID:19917671

NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142

Runx1

RUNX family transcription factor 1

involved_in

(PMID:9199349)

PMID:9199349

NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542

Zbtb46

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

MGI:5320483 (MGI:5320487|PMID:22615127)

PMID:22615127

MGI:5320487

NCBI chr 3:168,497,294...168,567,799
Ensembl chr 3:168,499,583...168,568,782

negative regulation of hematopoietic stem cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cebpa

CCAAT/enhancer binding protein alpha

acts_upstream_of_or_within

MGI:2177135 (MGI:3055255|PMID:15073037)

PMID:15073037

MGI:3055255

NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412

Mir221

microRNA 221

involved_in

(PMID:16330772)

PMID:16330772

NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573

Mir222

microRNA 222

involved_in

(PMID:16330772)

PMID:16330772

NCBI chr X:3,428,904...3,429,006
Ensembl chr X:3,428,904...3,429,006

Snai2

snail family transcriptional repressor 2

acts_upstream_of_or_within

MGI:2447174 (MGI:4436954|PMID:20032500)

PMID:20032500

MGI:4436954

NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200

negative regulation of hemocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dll1

delta like canonical Notch ligand 1

acts_upstream_of_or_within

(MGI:3774078|PMID:16621992)

PMID:16621992

MGI:3774078

NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179

negative regulation of hemopoiesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hspa9

heat shock protein family A (Hsp70) member 9

involved_in

ISS
ISO
IEA

GO_REF:0000024
(MGI:5784980|PMID:21123823)
GO_REF:0000107

UniProt
RGD
Ensembl

PMID:21123823

GO_REF:0000024 GO_REF:0000107 MGI:5784980

NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292

Il17d

interleukin 17D

involved_in

(PMID:12097364)

PMID:12097364

NCBI chr15:31,665,795...31,688,840

negative regulation of humoral immune response mediated by circulating immunoglobulin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fc gamma receptor 2B

acts_upstream_of_or_within

MGI:1857166 (MGI:3608295|PMID:12385742)

PMID:12385742

MGI:3608295

NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778

Foxj1

forkhead box J1

involved_in

(MGI:3589323|PMID:16002694)

PMID:16002694

MGI:3589323

NCBI chr10:101,566,299...101,570,249
Ensembl chr10:101,566,304...101,570,237

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1856074 (MGI:1095647|PMID:9254656)

PMID:9254656

GO_REF:0000107 MGI:1095647

NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984

negative regulation of immature T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gnrh1

gonadotropin releasing hormone 1

RGD

PMID:11092955

RGD:9685051

NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581

negative regulation of immature T cell proliferation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bmp4

bone morphogenetic protein 4

involved_in

IEA
ISS
ISO

GO_REF:0000107
GO_REF:0000024
(PMID:12421925)

Ensembl
UniProt
RGD

PMID:12421925

GO_REF:0000024 GO_REF:0000107

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

Cdkn2a

cyclin-dependent kinase inhibitor 2A

involved_in

(MGI:3615850|PMID:15964995)

PMID:15964995

MGI:3615850

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

Clec4g

C-type lectin domain family 4, member G

acts_upstream_of_or_within

MGI:5510586 (MGI:5475030|PMID:23487419)

PMID:23487419

MGI:5475030

NCBI chr12:1,780,370...1,785,027
Ensembl chr12:1,780,371...1,784,985

Erbb2

erb-b2 receptor tyrosine kinase 2

acts_upstream_of_or_within

(MGI:3695084|PMID:16230479)

PMID:16230479

MGI:3695084

NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078

Ihh

Indian hedgehog signaling molecule

involved_in

(MGI:3836494|PMID:19109233)

PMID:19109233

MGI:3836494

NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532

Tmem131l

transmembrane 131 like

involved_in

(PMID:23690469)

PMID:23690469

NCBI chr 2:169,257,659...169,391,773
Ensembl chr 2:169,258,289...169,391,711

negative regulation of immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Col3a1

collagen type III alpha 1 chain

involved_in

(PMID:16754721)

PMID:16754721

NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547

Ctla4

cytotoxic T-lymphocyte-associated protein 4

RGD

PMID:15849541

RGD:2302005

NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963

Fc gamma receptor 2B

acts_upstream_of_or_within

MGI:1857166 (MGI:1340171|PMID:10395649), (MGI:2179576|PMID:11994421), (MGI:78617|PMID:8552190)

PMID:8552190 PMID:10395649 PMID:11994421

MGI:1340171 MGI:2179576 MGI:78617

NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778

Fcrlb

Fc receptor-like B

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:4838081 (MGI:4837274|PMID:20869045)

PMID:20869045 PMID:21873635

MGI:4837274, RGD:13792537

NCBI chr13:83,148,685...83,157,157
Ensembl chr13:83,149,751...83,155,957

Foxp3

forkhead box P3

involved_in

(PMID:15652505)

PMID:15652505

NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838

inositol polyphosphate-5-phosphatase D

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2386884 (MGI:1354084|PMID:10704460)

PMID:10704460

GO_REF:0000107 MGI:1354084

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

Nlrp6

NLR family, pyrin domain containing 6

acts_upstream_of_or_within

MGI:5085850 (MGI:5432950|PMID:22763455)

PMID:22763455

MGI:5432950

NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113

Olfm4

olfactomedin 4

acts_upstream_of_or_within

MGI:4461923 (MGI:4457946|PMID:20534456)

PMID:20534456

MGI:4457946

NCBI chr15:55,385,100...55,429,687
Ensembl chr15:55,407,148...55,429,681

Pdcd1

programmed cell death 1

involved_in

(MGI:1929567|PMID:11209085), (MGI:2386198|PMID:10485649)

PMID:10485649 PMID:11209085

MGI:1929567 MGI:2386198

NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937

Tgfb1

transforming growth factor, beta 1

RGD

PMID:12130550

RGD:730199

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

Tgfb2

transforming growth factor, beta 2