regulation of immune system process - Ontology Report

(MGI:6201960|PMID:21873635)

NCBI chr 8:129,942,835...129,960,527
Ensembl chr 8:129,942,835...129,960,887

5730507C01Rik

RIKEN cDNA 5730507C01 gene

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr12:18,564,441...18,588,211
Ensembl chr12:18,564,511...18,585,255

Bcl6

B cell leukemia/lymphoma 6

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr16:23,783,800...23,807,623
Ensembl chr16:23,783,802...23,807,602

Bcl6b

B cell CLL/lymphoma 6, member B

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr11:70,114,953...70,120,624
Ensembl chr11:70,114,954...70,120,624

Ceacam1

CEA cell adhesion molecule 1

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 7:25,161,127...25,177,072
Ensembl chr 7:25,161,132...25,177,028

Ceacam10

CEA cell adhesion molecule 10

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 7:24,476,592...24,484,081
Ensembl chr 7:24,476,631...24,484,082

Ceacam2

CEA cell adhesion molecule 2

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 7:25,215,467...25,239,429
Ensembl chr 7:25,215,467...25,239,282

Ceacam20

CEA cell adhesion molecule 20

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 7:19,699,277...19,725,038
Ensembl chr 7:19,699,337...19,725,029

Ggt1

gamma-glutamyltransferase 1

involved_in

(MGI:5294309|PMID:12468440)
(MGI:6201960|PMID:21873635)

PMID:12468440 PMID:21873635

MGI:5294309 MGI:6201960

NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034

Gm17067

predicted gene 17067

involved_in

(MGI:6201960|PMID:21873635)

orosomucoid 1

involved_in

GO_REF:0000002 MGI:2152098

NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400

Orm2

orosomucoid 2

involved_in

GO_REF:0000002 MGI:2152098

NCBI chr 4:63,280,543...63,284,114
Ensembl chr 4:63,280,686...63,284,115

Patz1

POZ (BTB) and AT hook containing zinc finger 1

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr11:3,239,131...3,259,083
Ensembl chr11:3,238,874...3,259,083

Pip

prolactin induced protein

involved_in
acts_upstream_of_or_within

(MGI:6201960|PMID:21873635)
(MGI:5516495|PMID:20052012)

PMID:20052012 PMID:21873635

MGI:5516495 MGI:6201960

NCBI chr 6:41,824,483...41,828,999
Ensembl chr 6:41,824,469...41,828,999

Psg18

pregnancy specific beta-1-glycoprotein 18

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 7:18,079,669...18,088,963
Ensembl chr 7:18,079,347...18,088,934

Psg22

pregnancy-specific beta-1-glycoprotein 22

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 7:18,451,976...18,461,363
Ensembl chr 7:18,452,015...18,461,173

Psg29

pregnancy-specific beta-1-glycoprotein 29

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 7:16,937,402...16,949,681
Ensembl chr 7:16,937,402...16,949,685

Siae

sialic acid acetylesterase

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 9:37,525,117...37,559,554
Ensembl chr 9:37,466,994...37,560,951

Sva

seminal vesicle antigen

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 6:42,015,328...42,019,785
Ensembl chr 6:42,015,328...42,019,785

Sval1

seminal vesicle antigen-like 1

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 6:41,928,562...41,933,032
Ensembl chr 6:41,928,564...41,933,032

Sval2

seminal vesicle antigen-like 2

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 6:41,837,241...41,841,347
Ensembl chr 6:41,829,923...41,841,347

Sval3

seminal vesicle antigen-like 3

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 6:41,945,074...41,950,024
Ensembl chr 6:41,945,074...41,950,024

Zbtb1

zinc finger and BTB domain containing 1

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr12:76,416,825...76,443,729
Ensembl chr12:76,417,040...76,443,724

Zbtb12

zinc finger and BTB domain containing 12

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr17:35,113,535...35,115,843
Ensembl chr17:35,098,459...35,115,843

Zbtb2

zinc finger and BTB domain containing 2

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr10:4,317,074...4,353,114
Ensembl chr10:4,317,075...4,338,108

Zbtb20

zinc finger and BTB domain containing 20

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr16:42,728,008...43,462,442
Ensembl chr16:42,696,244...43,462,965

Zbtb24

zinc finger and BTB domain containing 24

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr10:41,326,354...41,341,578
Ensembl chr10:41,326,379...41,341,570

Zbtb25

zinc finger and BTB domain containing 25

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr12:76,387,168...76,416,988
Ensembl chr12:76,394,556...76,416,376

Zbtb26

zinc finger and BTB domain containing 26

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 2:37,322,180...37,333,184
Ensembl chr 2:37,322,180...37,333,147

Zbtb32

zinc finger and BTB domain containing 32

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 7:30,289,105...30,302,244
Ensembl chr 7:30,289,106...30,298,334

Zbtb33

zinc finger and BTB domain containing 33

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr X:37,278,670...37,285,923
Ensembl chr X:37,278,670...37,285,923

Zbtb34

zinc finger and BTB domain containing 34

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 2:33,296,120...33,321,336
Ensembl chr 2:33,296,120...33,321,336

Zbtb37

zinc finger and BTB domain containing 37

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 1:160,830,492...160,862,432
Ensembl chr 1:160,830,492...160,862,419

Zbtb39

zinc finger and BTB domain containing 39

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr10:127,575,399...127,583,218
Ensembl chr10:127,575,407...127,583,218

Zbtb45

zinc finger and BTB domain containing 45

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 7:12,737,828...12,745,212
Ensembl chr 7:12,737,825...12,743,961

Zbtb49

zinc finger and BTB domain containing 49

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 5:38,347,076...38,377,798
Ensembl chr 5:38,347,079...38,377,801

Zbtb6

zinc finger and BTB domain containing 6

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 2:37,315,512...37,320,931
Ensembl chr 2:37,315,512...37,333,183

Zfp131

zinc finger protein 131

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr13:120,226,722...120,253,070
Ensembl chr13:120,226,723...120,252,425

Zfp3

zinc finger protein 3

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr11:70,655,273...70,663,754
Ensembl chr11:70,655,035...70,663,754

Zfp422

zinc finger protein 422

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 6:116,600,977...116,605,960
Ensembl chr 6:116,600,977...116,605,960

Zfp958

zinc finger protein 958

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 8:4,663,170...4,682,572
Ensembl chr 8:4,663,167...4,680,231

Zfp965

zinc finger protein 965

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 2:175,311,755...175,449,916
Ensembl chr 2:175,435,771...175,445,653
Ensembl chr 2:175,435,771...175,445,653

activation of immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Nod2

nucleotide-binding oligomerization domain containing 2

acts_upstream_of_or_within

(MGI:3528786|PMID:15692051)

PMID:15692051

MGI:3528786

NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102

Trex1

three prime repair exonuclease 1

acts_upstream_of_or_within

(MGI:3818783|PMID:18045533)

PMID:19158676 PMID:21873635

PMID:18045533

MGI:3818783

NCBI chr 9:108,887,000...108,888,791
Ensembl chr 9:108,887,001...108,888,802

activation of innate immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Aim2

absent in melanoma 2

involved_in

IBA
IDA
ISO

(MGI:6201960|PMID:21873635)
(MGI:3839523|PMID:19158676)

GO_Central
UniProt
MGI

GO_REF:0000096 MGI:3839523 MGI:4834177 MGI:6201960

NCBI chr 1:173,177,105...173,293,606
Ensembl chr 1:173,178,445...173,293,606

Casp6

caspase 6

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752

Cgas

cyclic GMP-AMP synthase

involved_in

IMP
IDA
IBA
ISO

UniProt
GO_Central
MGI

PMID:21873635 PMID:23258413 PMID:23929945 PMID:24077100 PMID:29426904 More...

GO_REF:0000096 MGI:4834177 MGI:5487472 MGI:5505711 MGI:5908326 MGI:6119245 MGI:6201960 MGI:6754862 MGI:6810288 MGI:6828894

NCBI chr 9:78,337,800...78,350,519
Ensembl chr 9:78,337,808...78,350,519

Gm21992

predicted gene 21992

involved_in

(PMID:28712728)

PMID:28712728

NCBI chr19:4,792,941...4,861,662
Ensembl chr19:4,792,941...4,861,640

Hexim1

hexamethylene bis-acetamide inducible 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr11:103,007,151...103,010,551
Ensembl chr11:103,007,057...103,010,551

Hmgb1

high mobility group box 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299

Hsp90aa1

heat shock protein 90, alpha (cytosolic), class A member 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162

Ifi203

interferon activated gene 203

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:173,747,966...173,770,432
Ensembl chr 1:173,747,973...173,770,238

Ifi204

interferon activated gene 204

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 1:173,574,859...173,594,606
Ensembl chr 1:173,574,859...173,594,509

Ifi205

interferon activated gene 205

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 1:173,839,549...173,859,617
Ensembl chr 1:173,839,564...173,859,376

Ifi206

interferon activated gene 206

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:173,296,051...173,318,884
Ensembl chr 1:173,296,051...173,318,607

Ifi207

interferon activated gene 207

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:173,550,993...173,569,394
Ensembl chr 1:173,550,993...173,569,313

Ifi208

interferon activated gene 208

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:173,501,194...173,525,959
Ensembl chr 1:173,501,241...173,525,961

Ifi209

interferon activated gene 209

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:173,458,425...173,475,494
Ensembl chr 1:173,458,483...173,475,494

Ifi211

interferon activated gene 211

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 1:173,723,907...173,740,650
Ensembl chr 1:173,723,911...173,740,612

Ifi213

interferon activated gene 213

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:173,393,849...173,426,868
Ensembl chr 1:173,393,849...173,426,840

Ifi214

interferon activated gene 214

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:173,348,877...173,363,523
Ensembl chr 1:173,347,283...173,363,523

Matr3

matrin 3

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr18:35,695,211...35,725,098
Ensembl chr18:35,695,191...35,726,888

Mavs

mitochondrial antiviral signaling protein

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 2:131,075,445...131,089,945
Ensembl chr 2:131,075,983...131,089,945

Mndal

myeloid nuclear differentiation antigen like

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 1:173,684,786...173,708,035
Ensembl chr 1:173,676,692...173,708,447

Nlrc4

NLR family, CARD domain containing 4

involved_in

(MGI:3662990|PMID:16648852)

PMID:16648852

MGI:3662990

NCBI chr17:74,733,254...74,766,140
Ensembl chr17:74,732,433...74,766,137

Nono

non-POU-domain-containing, octamer binding protein

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr X:100,473,080...100,492,199
Ensembl chr X:100,472,924...100,492,197

Pqbp1

polyglutamine binding protein 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr X:7,760,758...7,765,508
Ensembl chr X:7,760,758...7,765,508

Prkdc

protein kinase, DNA activated, catalytic polypeptide

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099

Pspc1

paraspeckle protein 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr14:56,959,898...57,015,775
Ensembl chr14:56,958,167...57,015,773

Pycard

PYD and CARD domain containing

involved_in

(MGI:3839029|PMID:19158675)

PMID:19158675

GO_REF:0000096 MGI:3839029 MGI:4834177

NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039

Rbm14

RNA binding motif protein 14

involved_in

(PMID:28712728)

PMID:28712728

NCBI chr19:4,850,594...4,861,662
Ensembl chr19:4,850,597...4,861,662

Sfpq

splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 4:126,914,504...126,944,894
Ensembl chr 4:126,915,117...126,930,806

Sin3a

transcriptional regulator, SIN3A (yeast)

involved_in

MGI
ComplexPortal
UniProt
GO_Central

GO_REF:0000096 MGI:4834177

NCBI chr 9:56,979,271...57,035,652
Ensembl chr 9:56,979,324...57,035,650

Sting1

stimulator of interferon response cGAMP interactor 1

involved_in

ISO
IDA
IMP
IBA

(MGI:6827194|PMID:23910378)
(MGI:5487473|PMID:23258412), (MGI:5487515|PMID:21947006)
(MGI:6201960|PMID:21873635)

PMID:21873635 PMID:21947006 PMID:23258412 PMID:23910378

GO_REF:0000096 MGI:4834177 MGI:5487473 MGI:5487515 MGI:6201960 MGI:6827194

NCBI chr18:35,866,731...35,873,607
Ensembl chr18:35,866,732...35,873,607

Tbk1

TANK-binding kinase 1

acts_upstream_of_or_within

(MGI:3530402|PMID:15661922)

PMID:15661922

MGI:3530402

NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692

Tlr4

toll-like receptor 4

acts_upstream_of_or_within

(MGI:3530402|PMID:15661922)

PMID:15661922

MGI:3530402

NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521

Tlr9

toll-like receptor 9

involved_in

(MGI:5887188|PMID:25686612)

PMID:25686612

MGI:5887188

NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082

Tomm70a

translocase of outer mitochondrial membrane 70A

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr16:56,942,077...56,974,893
Ensembl chr16:56,942,066...56,977,068

Trim12a

tripartite motif-containing 12A

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 7:103,949,100...103,964,765
Ensembl chr 7:103,949,101...103,964,673

Trim12c

tripartite motif-containing 12C

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 7:103,987,961...104,002,649
Ensembl chr 7:103,987,961...104,002,569

Trim30a

tripartite motif-containing 30A

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 7:104,058,232...104,114,400
Ensembl chr 7:104,058,232...104,114,400

Trim30b

tripartite motif-containing 30B

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 7:104,004,605...104,007,853
Ensembl chr 7:104,004,589...104,019,091

Trim30c

tripartite motif-containing 30C

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 7:104,028,324...104,050,059
Ensembl chr 7:104,031,272...104,050,044

Trim30d

tripartite motif-containing 30D

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 7:104,119,221...104,157,062
Ensembl chr 7:104,119,221...104,157,056

Trim5

tripartite motif-containing 5

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 7:103,912,593...103,937,448
Ensembl chr 7:103,912,593...103,937,301

Xrcc5

X-ray repair complementing defective repair in Chinese hamster cells 5

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:72,346,576...72,434,112
Ensembl chr 1:72,346,586...72,434,111

Xrcc6

X-ray repair complementing defective repair in Chinese hamster cells 6

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr15:81,868,805...81,924,286
Ensembl chr15:81,872,036...81,924,286

Zbp1

Z-DNA binding protein 1

involved_in

IDA
IMP

(MGI:6434626|PMID:32296175), (MGI:6436412|PMID:32200799)
(MGI:6453154|PMID:32350114), (MGI:6490907|PMID:33109609)

PMID:32200799 PMID:32296175 PMID:32350114 PMID:33109609

MGI:6434626 MGI:6436412 MGI:6453154 MGI:6490907

NCBI chr 2:173,048,405...173,060,715
Ensembl chr 2:173,048,405...173,060,716

Zcchc3

zinc finger, CCHC domain containing 3

involved_in

IMP
IBA
ISO

(MGI:6209107|PMID:30135424), (MGI:6271678|PMID:30193849)
(MGI:6201960|PMID:21873635)

UniProt
GO_Central
MGI

PMID:21873635 PMID:30135424 PMID:30193849

GO_REF:0000096 MGI:4834177 MGI:6201960 MGI:6209107 MGI:6271678

NCBI chr 2:152,253,876...152,256,964
Ensembl chr 2:152,253,875...152,256,947

Znfx1

zinc finger, NFX1-type containing 1

involved_in

(MGI:6384069|PMID:31685995)

PMID:31685995

MGI:6384069

NCBI chr 2:166,877,710...166,904,935
Ensembl chr 2:166,877,713...166,904,935

activation of membrane attack complex

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cfh

complement component factor h

acts_upstream_of_or_within

(MGI:4837299|PMID:20813971)

PMID:20813971

MGI:4837299

NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502

antigen receptor-mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bcar1

breast cancer anti-estrogen resistance 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 8:112,437,106...112,470,481
Ensembl chr 8:112,437,106...112,470,441

Cd19

CD19 antigen

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061

Lax1

lymphocyte transmembrane adaptor 1

involved_in
acts_upstream_of_or_within

(MGI:6201960|PMID:21873635)
(MGI:3578441|PMID:15843560)

PMID:15843560 PMID:21873635

MGI:3578441 MGI:6201960

NCBI chr 1:133,606,767...133,620,760
Ensembl chr 1:133,606,829...133,617,846

Sh2b2

SH2B adaptor protein 2

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 5:136,247,002...136,275,452
Ensembl chr 5:136,247,001...136,275,410

B cell costimulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd320

CD320 antigen

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr17:34,062,065...34,068,748
Ensembl chr17:34,062,065...34,068,748

Il4

interleukin 4

involved_in
acts_upstream_of_or_within

IBA
IDA

(MGI:6201960|PMID:21873635)
(MGI:3817382|PMID:18762567)

PMID:18762567 PMID:21873635

MGI:3817382 MGI:6201960

NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496

Tnfrsf13c

tumor necrosis factor receptor superfamily, member 13c

acts_upstream_of_or_within
involved_in

(MGI:3051152|PMID:15240667)
(MGI:6201960|PMID:21873635)

PMID:15240667 PMID:21873635

MGI:3051152 MGI:6201960

NCBI chr15:82,105,943...82,108,581
Ensembl chr15:82,105,944...82,108,570

Tnfsf13b

tumor necrosis factor (ligand) superfamily, member 13b

acts_upstream_of_or_within

(MGI:3051152|PMID:15240667)

PMID:15240667

MGI:3051152

NCBI chr 8:10,056,229...10,086,000
Ensembl chr 8:10,056,467...10,089,072

B cell receptor apoptotic signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bax

BCL2-associated X protein

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322

Nfkbiz

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta

involved_in

(MGI:5508814|PMID:23728777)

PMID:23728777

MGI:5508814

NCBI chr16:55,631,740...55,659,004
Ensembl chr16:55,631,738...55,659,262

B cell receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abl1

c-abl oncogene 1, non-receptor tyrosine kinase

acts_upstream_of_or_within

(MGI:1927957|PMID:11120811), (MGI:3839222|PMID:19228876)

PMID:11120811 PMID:19228876

MGI:1927957 MGI:3839222

NCBI chr 2:31,578,256...31,697,105
Ensembl chr 2:31,578,388...31,694,239

Bcar1

breast cancer anti-estrogen resistance 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 8:112,437,106...112,470,481
Ensembl chr 8:112,437,106...112,470,441

Bcl2

B cell leukemia/lymphoma 2

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004

Blk

B lymphoid kinase

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr14:63,610,286...63,654,636
Ensembl chr14:63,610,285...63,654,486

Blnk

B cell linker

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr19:40,917,371...40,982,664
Ensembl chr19:40,917,371...40,982,978

Bmx

BMX non-receptor tyrosine kinase

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr X:162,975,838...163,041,189
Ensembl chr X:162,975,838...163,041,189

Btk

Bruton agammaglobulinemia tyrosine kinase

involved_in

(MGI:6201960|PMID:21873635)

PMID:9254656 PMID:21873635 PMID:23499492

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr X:133,443,083...133,484,366
Ensembl chr X:133,443,085...133,484,319

Cd19

CD19 antigen

involved_in
acts_upstream_of_or_within

IMP
IBA
IDA

(MGI:5476553|PMID:23499492)
(MGI:6201960|PMID:21873635)
(MGI:1095647|PMID:9254656)

UniProt
GO_Central
MGI

MGI:1095647 MGI:5476553 MGI:6201960

NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061

Cd38

CD38 antigen

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 5:44,026,151...44,069,716
Ensembl chr 5:44,025,895...44,069,717

Cd79a

CD79A antigen (immunoglobulin-associated alpha)

involved_in
acts_upstream_of_or_within

IBA
IDA

(MGI:6201960|PMID:21873635)
(MGI:79455|PMID:8626447)
(MGI:3521842|PMID:1373499), (MGI:79455|PMID:8626447)

PMID:1373499 PMID:8626447 PMID:21873635

MGI:3521842 MGI:6201960 MGI:79455

NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622

Cd79b

CD79B antigen

acts_upstream_of_or_within
involved_in

(MGI:3521842|PMID:1373499), (MGI:79455|PMID:8626447)
(MGI:79455|PMID:8626447)
(MGI:6201960|PMID:21873635)

PMID:1373499 PMID:8626447 PMID:21873635

MGI:3521842 MGI:6201960 MGI:79455

NCBI chr11:106,202,167...106,205,388
Ensembl chr11:106,202,167...106,205,588

Ctla4

cytotoxic T-lymphocyte-associated protein 4

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991

Fcrl5

Fc receptor-like 5

acts_upstream_of

IDA
IGI

(MGI:5471851|PMID:23509253)

PMID:23509253

MGI:5471851

NCBI chr 3:87,343,084...87,407,985
Ensembl chr 3:87,343,080...87,407,985

Grb2

growth factor receptor bound protein 2

involved_in

(MGI:7316616|PMID:9199344)

PMID:9199344

MGI:7316616

NCBI chr11:115,534,871...115,599,423
Ensembl chr11:115,534,871...115,599,423

Ifi211

interferon activated gene 211

involved_in

(PMID:17875758)

PMID:17875758

NCBI chr 1:173,723,907...173,740,650
Ensembl chr 1:173,723,911...173,740,612

Ighm

immunoglobulin heavy constant mu

acts_upstream_of_or_within

(MGI:1095647|PMID:9254656), (MGI:3521842|PMID:1373499), (MGI:77358|PMID:7499277), (MGI:79455|PMID:8626447)

PMID:1373499 PMID:7499277 PMID:8626447 PMID:9254656

MGI:1095647 MGI:3521842 MGI:77358 MGI:79455

NCBI chr12:113,382,446...113,386,350
Ensembl chr12:113,382,178...113,386,350

Itk

IL2 inducible T cell kinase

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr11:46,215,975...46,280,342
Ensembl chr11:46,215,977...46,280,342

Klhl6

kelch-like 6

involved_in

(MGI:3603885|PMID:16166635)

PMID:12514734 PMID:21873635

PMID:16166635

MGI:3603885

NCBI chr16:19,765,242...19,801,832
Ensembl chr16:19,765,246...19,801,787

Lat2

linker for activation of T cells family, member 2

involved_in

ISO
IBA
ISS

(MGI:6201960|PMID:21873635)
(MGI:3710721|PMID:12514734)

MGI
GO_Central
HGNC-UCL

GO_REF:0000096 MGI:3710721 MGI:4834177 MGI:6201960

NCBI chr 5:134,628,957...134,648,637
Ensembl chr 5:134,628,876...134,643,879

Lck

lymphocyte protein tyrosine kinase

acts_upstream_of_or_within
involved_in

(MGI:77358|PMID:7499277)
(MGI:6201960|PMID:21873635)

PMID:7499277 PMID:21873635

MGI:6201960 MGI:77358

NCBI chr 4:129,442,137...129,467,434
Ensembl chr 4:129,442,137...129,467,434

Lime1

Lck interacting transmembrane adaptor 1

acts_upstream_of_or_within
involved_in

(MGI:3769059|PMID:16249387)
(MGI:6201960|PMID:21873635)

PMID:16249387 PMID:21873635

MGI:3769059 MGI:6201960

NCBI chr 2:181,023,028...181,025,421
Ensembl chr 2:181,021,871...181,025,421

LYN proto-oncogene, Src family tyrosine kinase

acts_upstream_of_or_within

IGI
IDA

(MGI:5471851|PMID:23509253)
(MGI:77358|PMID:7499277)

PMID:7499277 PMID:23509253

MGI:5471851 MGI:77358

NCBI chr 4:3,676,865...3,791,612
Ensembl chr 4:3,678,115...3,813,122

Mapk1

mitogen-activated protein kinase 1

acts_upstream_of_or_within

(MGI:1095647|PMID:9254656)

PMID:9254656

MGI:1095647

NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317

Mef2c

myocyte enhancer factor 2C

involved_in

(MGI:3829850|PMID:18955699)

PMID:18955699

MGI:3829850

NCBI chr13:83,652,136...83,815,198
Ensembl chr13:83,652,153...83,815,199

Ms4a1

membrane-spanning 4-domains, subfamily A, member 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr19:11,227,043...11,243,513
Ensembl chr19:11,227,039...11,243,605

Nckap1l

NCK associated protein 1 like

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237

Nfam1

Nfat activating molecule with ITAM motif 1

involved_in
acts_upstream_of_or_within

IBA
IDA

(MGI:6201960|PMID:21873635)
(MGI:3044463|PMID:15143214)

PMID:15143214 PMID:21873635

MGI:3044463 MGI:6201960

NCBI chr15:82,880,937...82,917,598
Ensembl chr15:82,877,174...82,917,507

Nfatc2

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 2:168,318,330...168,443,900
Ensembl chr 2:168,318,330...168,443,577

Nfkb1

nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105

involved_in

(MGI:3710273|PMID:17367755)

PMID:17367755

MGI:3710273

NCBI chr 3:135,290,416...135,397,728
Ensembl chr 3:135,290,416...135,397,308

Nfkbia

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha

involved_in

(MGI:3710273|PMID:17367755)

PMID:17367755

MGI:3710273

NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432

Nfkbiz

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta

involved_in

(MGI:3710273|PMID:17367755)

PMID:17367755

MGI:3710273

NCBI chr16:55,631,740...55,659,004
Ensembl chr16:55,631,738...55,659,262

Plcg2

phospholipase C, gamma 2

involved_in

(MGI:1861532|PMID:10925250)

PMID:10925250

GO_REF:0000096 MGI:1861532 MGI:4834177

NCBI chr 8:118,225,014...118,361,881
Ensembl chr 8:118,225,030...118,361,881

Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 7:130,462,281...130,515,224
Ensembl chr 7:130,467,486...130,515,042

Prkcb

protein kinase C, beta

involved_in

(MGI:3626015|PMID:12118249)

PMID:12118249

MGI:3626015

NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

acts_upstream_of_or_within

IGI
IMP

(MGI:5471851|PMID:23509253)
(MGI:1095647|PMID:9254656)

PMID:9254656 PMID:23509253

MGI:1095647 MGI:5471851

NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677

Ptprc

protein tyrosine phosphatase, receptor type, C

acts_upstream_of_or_within
involved_in

(MGI:77358|PMID:7499277)
(MGI:1095647|PMID:9254656)
(MGI:3687418|PMID:8692271)

PMID:7499277 PMID:8692271 PMID:9254656

MGI:1095647 MGI:3687418 MGI:77358

NCBI chr 1:137,990,597...138,103,491
Ensembl chr 1:137,990,599...138,103,446

Rftn1

raftlin lipid raft linker 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr17:50,300,287...50,497,525
Ensembl chr17:50,299,285...50,497,702

Sh2b2

SH2B adaptor protein 2

involved_in
acts_upstream_of_or_within

(MGI:1859033|PMID:10872802)

PMID:10872802

GO_REF:0000096 MGI:1859033 MGI:4834177

NCBI chr 5:136,247,002...136,275,452
Ensembl chr 5:136,247,001...136,275,410

Shc1

src homology 2 domain-containing transforming protein C1

involved_in

(MGI:7316616|PMID:9199344)

PMID:9199344

MGI:7316616

NCBI chr 3:89,325,858...89,337,336
Ensembl chr 3:89,325,750...89,337,334

Sos1

SOS Ras/Rac guanine nucleotide exchange factor 1

involved_in

(MGI:5547878|PMID:24043312)

PMID:24043312

MGI:5547878

NCBI chr17:80,701,181...80,787,882
Ensembl chr17:80,701,180...80,787,882

Syk

spleen tyrosine kinase

acts_upstream_of_or_within
involved_in

IDA
ISO
IBA

(MGI:77358|PMID:7499277), (MGI:79455|PMID:8626447)
(MGI:7316616|PMID:9199344)
(MGI:6201960|PMID:21873635)

PMID:7499277 PMID:8626447 PMID:9199344 PMID:21873635

GO_REF:0000096 MGI:4834177 MGI:6201960 MGI:7316616 MGI:77358 MGI:79455

NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828

Tec

tec protein tyrosine kinase

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 5:72,913,061...73,025,997
Ensembl chr 5:72,913,059...73,025,826

Vav3

vav 3 oncogene

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 3:109,247,757...109,593,010
Ensembl chr 3:109,247,969...109,593,014

CD4-positive, alpha-beta T cell costimulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd81

CD81 antigen

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 7:142,606,487...142,621,667
Ensembl chr 7:142,606,476...142,621,671

Tnfsf4

tumor necrosis factor (ligand) superfamily, member 4

involved_in

(MGI:4819294|PMID:20639485)

PMID:20639485

MGI:4819294

NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981

cell surface pattern recognition receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd14

CD14 antigen

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851

Clec7a

C-type lectin domain family 7, member a

acts_upstream_of_or_within

(MGI:3042099|PMID:12719478)

PMID:12719478

MGI:3042099

NCBI chr 6:129,438,554...129,449,748
Ensembl chr 6:129,438,554...129,449,742

Fcnb

ficolin B

involved_in

(PMID:21037097)

PMID:21037097

NCBI chr 2:27,966,491...27,974,921
Ensembl chr 2:27,966,390...27,974,897

Ffar2

free fatty acid receptor 2

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 7:30,517,778...30,523,200
Ensembl chr 7:30,517,773...30,523,200

Lbp

lipopolysaccharide binding protein

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 2:158,148,413...158,174,772
Ensembl chr 2:158,148,413...158,174,772

Masp1

mannan-binding lectin serine peptidase 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr16:23,261,778...23,340,127
Ensembl chr16:23,268,167...23,339,565

Masp2

mannan-binding lectin serine peptidase 2

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 4:148,679,079...148,699,939
Ensembl chr 4:148,687,011...148,699,956

Mbl2

mannose-binding lectin (protein C) 2

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087

Tlr2

toll-like receptor 2

acts_upstream_of_or_within

(MGI:3042099|PMID:12719478)

PMID:12719478

MGI:3042099

NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074

complement activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

complement component 2 (within H-2S)

involved_in

GO_Central
ComplexPortal
MGI
RGD

GO_REF:0000096 MGI:4834177

NCBI chr17:35,081,578...35,101,076
Ensembl chr17:35,081,580...35,117,241

complement component 3

involved_in
acts_upstream_of_or_within

IBA
NAS
ISO
IDA
IMP

PMID:18947875 PMID:20712003 PMID:21873635 PMID:23901101 PMID:25284781 More...

GO_REF:0000096 MGI:3833206 MGI:4417868 MGI:4834177 MGI:5617896 MGI:6201960 MGI:6869965 MGI:6870995 RGD:5129529

NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136

C4a

complement component 4A (Rodgers blood group)

involved_in
acts_upstream_of_or_within

BHF-UCL
ComplexPortal
MGI

(PMID:19302245)
(PMID:12878586), (PMID:6906228)
(MGI:51812|PMID:1438267), (MGI:66045|PMID:8133084)

PMID:1438267 PMID:6906228 PMID:8133084 PMID:12878586 PMID:19302245

MGI:51812 MGI:66045

NCBI chr17:35,028,069...35,042,436
Ensembl chr17:35,028,069...35,042,440

C4b

complement component 4B (Chido blood group)

involved_in
acts_upstream_of_or_within

(MGI:6201960|PMID:21873635)
(MGI:2429478|PMID:12421924)

PMID:12421924 PMID:21873635

MGI:2429478 MGI:6201960

NCBI chr17:34,947,249...34,962,876
Ensembl chr17:34,947,354...34,962,856

complement component 6

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr15:4,756,550...4,833,527
Ensembl chr15:4,756,657...4,844,449

complement component 7

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr15:5,017,232...5,093,255
Ensembl chr15:5,018,244...5,093,222

C8a

complement component 8, alpha polypeptide

acts_upstream_of_or_within
involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000008 MGI:2154458 MGI:6201960

NCBI chr 4:104,672,876...104,733,684
Ensembl chr 4:104,672,876...104,733,595

C8b

complement component 8, beta polypeptide

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 4:104,623,514...104,661,745
Ensembl chr 4:104,623,514...104,661,745

C8g

complement component 8, gamma polypeptide

involved_in

GO_REF:0000002 MGI:2152098

NCBI chr 2:25,388,662...25,391,919
Ensembl chr 2:25,388,663...25,391,731

complement component 9

involved_in

(MGI:6201960|PMID:21873635)

PMID:6906329 PMID:23901101 PMID:27031863

NCBI chr15:6,474,827...6,528,306
Ensembl chr15:6,474,808...6,528,232

Cfb

complement factor B

involved_in

ISO
NAS

(MGI:6869965|PMID:23901101), (MGI:6870995|PMID:27031863)

RGD
ComplexPortal

MGI:6869965 MGI:6870995 RGD:2311339

NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494

Cfh

complement component factor h

acts_upstream_of_or_within
involved_in

IMP
IDA
IBA
ISO
IGI

MGI
GO_Central
RGD

PMID:12911541 PMID:15574507 PMID:17517971 PMID:17921253 PMID:19411110 More...

GO_REF:0000096 MGI:3639077 MGI:3760048 MGI:3760334 MGI:3848672 MGI:3849508 MGI:4821502 MGI:4830025 MGI:4834177 MGI:5883383 MGI:6201960 RGD:1599888

NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502

Cfhr1

complement factor H-related 1

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 1:139,474,802...139,487,960
Ensembl chr 1:139,474,791...139,488,010

Cfhr2

complement factor H-related 2

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 1:139,738,030...139,786,437
Ensembl chr 1:139,731,905...139,786,456

Cfhr4

complement factor H-related 4

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 1:139,625,657...139,708,977
Ensembl chr 1:139,625,361...139,708,981

Cfi

complement component factor i

involved_in

(MGI:3773599|PMID:18202746)

PMID:18202746

MGI:3773599

NCBI chr 3:129,630,376...129,668,981
Ensembl chr 3:129,629,533...129,668,981

Cfp

complement factor properdin

involved_in

(MGI:6869965|PMID:23901101)

PMID:23901101

MGI:6869965

NCBI chr X:20,791,693...20,797,794
Ensembl chr X:20,791,693...20,797,794

Colec11

collectin sub-family member 11

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr12:28,644,171...28,673,458
Ensembl chr12:28,644,172...28,673,376

complement component (3b/4b) receptor 1-like

acts_upstream_of_or_within

(MGI:4821502|PMID:20675597)

PMID:20675597

MGI:4821502

NCBI chr 1:194,781,019...194,813,878
Ensembl chr 1:194,779,690...194,813,894

Fcna

ficolin A

involved_in

(PMID:22851708)

PMID:22851708

NCBI chr 2:25,514,677...25,525,448
Ensembl chr 2:25,514,678...25,518,042

hemolytic complement

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450

Rgcc

regulator of cell cycle

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr14:79,526,190...79,539,075
Ensembl chr14:79,526,196...79,539,085

complement activation, alternative pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

complement component 3

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136

C8a

complement component 8, alpha polypeptide

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 4:104,672,876...104,733,684
Ensembl chr 4:104,672,876...104,733,595

C8b

complement component 8, beta polypeptide

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 4:104,623,514...104,661,745
Ensembl chr 4:104,623,514...104,661,745

C8g

complement component 8, gamma polypeptide

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 2:25,388,662...25,391,919
Ensembl chr 2:25,388,663...25,391,731

complement component 9

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr15:6,474,827...6,528,306
Ensembl chr15:6,474,808...6,528,232

Cfb

complement factor B

acts_upstream_of_or_within

IGI
IMP
TAS

(MGI:6100611|PMID:27564415)
(MGI:1096110|PMID:9238044)
(MGI:55460|PMID:6550027)

PMID:6550027 PMID:9238044 PMID:27564415

MGI:1096110 MGI:55460 MGI:6100611

NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494

Cfd

complement factor D (adipsin)

acts_upstream_of_or_within

(MGI:6100611|PMID:27564415)

PMID:27564415

MGI:6100611

NCBI chr10:79,726,687...79,728,489
Ensembl chr10:79,726,687...79,728,489

Cfh

complement component factor h

acts_upstream_of_or_within
acts_upstream_of_or_within_negative_effect

IMP
IGI

(MGI:6100611|PMID:27564415)
(MGI:4421084|PMID:19828624)

PMID:19828624 PMID:27564415

MGI:4421084 MGI:6100611

NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502

Cfp

complement factor properdin

involved_in

(MGI:3773929|PMID:18292556)

PMID:18292556

MGI:3773929

NCBI chr X:20,791,693...20,797,794
Ensembl chr X:20,791,693...20,797,794

Cr2

complement receptor 2

involved_in
acts_upstream_of_or_within_negative_effect

ISO
IGI

(MGI:4421084|PMID:19828624)

PMID:19828624

GO_REF:0000096 MGI:4421084 MGI:4834177

NCBI chr 1:194,819,120...194,859,096
Ensembl chr 1:194,819,119...194,859,024

hemolytic complement

acts_upstream_of_or_within

PMID:11527969 PMID:11901193

GO_REF:0000004 MGI:1354194

NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450

complement activation, classical pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

C1qa

complement component 1, q subcomponent, alpha polypeptide

acts_upstream_of_or_within
involved_in

IMP
NAS
ISO

(MGI:2177393|PMID:11901193)
(MGI:6869966|PMID:11527969)

MGI
ComplexPortal

GO_REF:0000096 MGI:2177393 MGI:4834177 MGI:6869966

NCBI chr 4:136,623,227...136,626,155
Ensembl chr 4:136,623,228...136,626,114

C1qb

complement component 1, q subcomponent, beta polypeptide

involved_in

ISO
NAS

(MGI:6869966|PMID:11527969)

MGI
ComplexPortal

GO_REF:0000096 MGI:4834177 MGI:6869966

NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498

C1qbp

complement component 1, q subcomponent binding protein

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr11:70,868,672...70,873,852
Ensembl chr11:70,868,662...70,873,852

C1qc

complement component 1, q subcomponent, C chain

involved_in

ISO
NAS

(MGI:6869966|PMID:11527969)

MGI
ComplexPortal

GO_REF:0000096 MGI:4834177 MGI:6869966

NCBI chr 4:136,617,112...136,620,242
Ensembl chr 4:136,617,115...136,620,376

C1ra

complement component 1, r subcomponent A

involved_in

(MGI:6869966|PMID:11527969)

NCBI chr 6:124,489,580...124,500,399
Ensembl chr 6:124,489,364...124,500,402

C1rb

complement component 1, r subcomponent B

involved_in

(MGI:6869966|PMID:11527969)

NCBI chr 6:124,547,389...124,558,003
Ensembl chr 6:124,547,253...124,558,130

C1rl

complement component 1, r subcomponent-like

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 6:124,470,072...124,487,602
Ensembl chr 6:124,470,072...124,487,602

C1s1

complement component 1, s subcomponent 1

involved_in

(MGI:6869966|PMID:11527969)

NCBI chr 6:124,507,303...124,519,340
Ensembl chr 6:124,507,304...124,519,318

C1s2

complement component 1, s subcomponent 2

involved_in

(MGI:6869966|PMID:11527969)

NCBI chr 6:124,601,584...124,613,044
Ensembl chr 6:124,601,584...124,613,044

complement component 2 (within H-2S)

involved_in
acts_upstream_of_or_within

GO_REF:0000002 GO_REF:0000004 MGI:1354194 MGI:2152098

NCBI chr17:35,081,578...35,101,076
Ensembl chr17:35,081,580...35,117,241

complement component 3

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136

C4bp

complement component 4 binding protein

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 1:130,563,658...130,589,394
Ensembl chr 1:130,562,510...130,589,369

C8a

complement component 8, alpha polypeptide

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 4:104,672,876...104,733,684
Ensembl chr 4:104,672,876...104,733,595

C8b

complement component 8, beta polypeptide

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 4:104,623,514...104,661,745
Ensembl chr 4:104,623,514...104,661,745

C8g

complement component 8, gamma polypeptide

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 2:25,388,662...25,391,919
Ensembl chr 2:25,388,663...25,391,731

complement component 9

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr15:6,474,827...6,528,306
Ensembl chr15:6,474,808...6,528,232

Cd55

CD55 molecule, decay accelerating factor for complement

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 1:130,357,526...130,392,746
Ensembl chr 1:130,366,764...130,390,481

Cd55b

CD55 molecule, decay accelerating factor for complement B

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 1:130,316,263...130,350,831
Ensembl chr 1:130,316,274...130,350,746

Cfi

complement component factor i

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 3:129,630,376...129,668,981
Ensembl chr 3:129,629,533...129,668,981

complement component (3b/4b) receptor 1-like

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 1:194,781,019...194,813,878
Ensembl chr 1:194,779,690...194,813,894

Cr2

complement receptor 2

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 1:194,819,120...194,859,096
Ensembl chr 1:194,819,119...194,859,024

Crp

C-reactive protein, pentraxin-related

involved_in

PMID:16367929

GO_REF:0000096 MGI:4417868 RGD:1580273

NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598

hemolytic complement

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450

Igh-8

immunoglobulin heavy chain 8 (heavy chain of IgG3)

acts_upstream_of_or_within

(MGI:2177393|PMID:11901193)

immunoglobulin heavy constant gamma 1 (G1m marker)

acts_upstream_of_or_within

(MGI:2683928|PMID:6952213)

PMID:6952213

MGI:2683928

NCBI chr12:113,290,161...113,294,143
Ensembl chr12:113,288,860...113,294,143

Ighg2a

immunoglobulin heavy constant gamma 2A

acts_upstream_of_or_within

(MGI:2177393|PMID:11901193), (MGI:2683928|PMID:6952213)

PMID:6952213 PMID:11901193

MGI:2177393 MGI:2683928

Ighg2b

immunoglobulin heavy constant gamma 2B

acts_upstream_of_or_within

(MGI:2177393|PMID:11901193), (MGI:2683928|PMID:6952213)

PMID:6952213 PMID:11901193

MGI:2177393 MGI:2683928

NCBI chr12:113,267,934...113,271,553
Ensembl chr12:113,266,585...113,271,553

Masp2

mannan-binding lectin serine peptidase 2

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 4:148,679,079...148,699,939
Ensembl chr 4:148,687,011...148,699,956

Mbl1

mannose-binding lectin (protein A) 1

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr14:40,873,413...40,885,861
Ensembl chr14:40,873,415...40,881,558

Mbl2

mannose-binding lectin (protein C) 2

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087

Serping1

serine (or cysteine) peptidase inhibitor, clade G, member 1

acts_upstream_of_or_within

GO_REF:0000004 MGI:1354194

NCBI chr 2:84,595,704...84,605,778
Ensembl chr 2:84,595,731...84,605,788

complement activation, lectin pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Colec10

collectin sub-family member 10

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr15:54,274,170...54,329,755
Ensembl chr15:54,274,170...54,329,754

Colec11

collectin sub-family member 11

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr12:28,644,171...28,673,458
Ensembl chr12:28,644,172...28,673,376

Fcna

ficolin A

acts_upstream_of_or_within
involved_in

IDA
ISO

(MGI:5473786|PMID:16328467)
(PMID:11907111)

PMID:11907111 PMID:16328467

MGI:5473786

NCBI chr 2:25,514,677...25,525,448
Ensembl chr 2:25,514,678...25,518,042

Fcnb

ficolin B

involved_in
acts_upstream_of_or_within

ISO
IEA

(PMID:16116205)

ComplexPortal
UniProt

PMID:16116205

GO_REF:0000004 MGI:1354194

NCBI chr 2:27,966,491...27,974,921
Ensembl chr 2:27,966,390...27,974,897

Krt1

keratin 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr15:101,753,861...101,759,221
Ensembl chr15:101,753,861...101,759,229

Masp1

mannan-binding lectin serine peptidase 1

involved_in

(MGI:3789229|PMID:18424734)

PMID:18424734

GO_REF:0000096 MGI:3789229 MGI:4834177

NCBI chr16:23,261,778...23,340,127
Ensembl chr16:23,268,167...23,339,565

Masp2

mannan-binding lectin serine peptidase 2

involved_in
acts_upstream_of_or_within

IBA
IDA
ISO

(MGI:6201960|PMID:21873635)
(MGI:5473786|PMID:16328467)

PMID:16328467 PMID:21873635

GO_REF:0000096 MGI:4834177 MGI:5473786 MGI:6201960

NCBI chr 4:148,679,079...148,699,939
Ensembl chr 4:148,687,011...148,699,956

Mbl1

mannose-binding lectin (protein A) 1

acts_upstream_of_or_within
involved_in

IGI
ISO
IDA

(MGI:3577322|PMID:15148336)

MGI
RGD

PMID:15148336 PMID:16272342

GO_REF:0000096 MGI:3577322 MGI:4417868 RGD:1582134

NCBI chr14:40,873,413...40,885,861
Ensembl chr14:40,873,415...40,881,558

Mbl2

mannose-binding lectin (protein C) 2

involved_in
acts_upstream_of_or_within

ISO
IDA
IMP
IGI

(PMID:11549596)
(PMID:22691502), (PMID:35102342)
(MGI:3577322|PMID:15148336)

UniProt
ComplexPortal
MGI

PMID:11549596 PMID:15148336 PMID:22691502 PMID:35102342

GO_REF:0000008 MGI:2154458 MGI:3577322

NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087

complement component C5a signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

C5ar1

complement component 5a receptor 1

involved_in
acts_upstream_of_or_within

(MGI:51391|PMID:1401897)

MGI
GOC

PMID:1401897

GO_REF:0000096 MGI:4834177 MGI:51391

NCBI chr 7:15,980,668...15,993,465
Ensembl chr 7:15,980,668...15,993,465

C5ar2

complement component 5a receptor 2

acts_upstream_of_or_within

(MGI:6201960|PMID:21873635)

GOC

NCBI chr 7:15,968,512...15,978,079
Ensembl chr 7:15,968,510...15,978,079

complement receptor mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

C3ar1

complement component 3a receptor 1

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 6:122,824,099...122,833,116
Ensembl chr 6:122,824,097...122,833,120

C5ar1

complement component 5a receptor 1

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 7:15,980,668...15,993,465
Ensembl chr 7:15,980,668...15,993,465

C5ar2

complement component 5a receptor 2

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 7:15,968,512...15,978,079
Ensembl chr 7:15,968,510...15,978,079

Cmklr1

chemerin chemokine-like receptor 1

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 5:113,750,415...113,792,971
Ensembl chr 5:113,750,415...113,788,487

Fpr-rs3

formyl peptide receptor, related sequence 3

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr17:20,844,108...20,845,139
Ensembl chr17:20,844,108...20,845,139

Fpr-rs4

formyl peptide receptor, related sequence 4

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr17:18,241,995...18,242,966
Ensembl chr17:18,241,995...18,242,966

Fpr-rs6

formyl peptide receptor, related sequence 6

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr17:20,402,340...20,403,359
Ensembl chr17:20,402,340...20,403,359

Fpr-rs7

formyl peptide receptor, related sequence 7

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr17:20,333,472...20,334,488
Ensembl chr17:20,333,472...20,334,488

Fpr1

formyl peptide receptor 1

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr17:18,096,733...18,104,201
Ensembl chr17:18,096,733...18,104,202

Fpr2

formyl peptide receptor 2

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr17:18,108,086...18,114,214
Ensembl chr17:18,108,086...18,114,214

Fpr3

formyl peptide receptor 3

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr17:18,190,720...18,191,939
Ensembl chr17:18,108,114...18,191,939

Gpld1

glycosylphosphatidylinositol specific phospholipase D1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr13:25,127,135...25,175,919
Ensembl chr13:25,127,135...25,176,484

Gpr33

G protein-coupled receptor 33

involved_in

(MGI:6201960|PMID:21873635)

PMID:21873635 PMID:30111836

NCBI chr12:52,069,786...52,074,846
Ensembl chr12:52,069,786...52,074,846

cytosolic pattern recognition receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Alpk1

alpha-kinase 1

involved_in

ISO
IBA
IMP

(MGI:6201960|PMID:21873635)
(MGI:6196443|PMID:30111836)

MGI
GO_Central
UniProt

GO_REF:0000096 MGI:4834177 MGI:6196443 MGI:6201960

NCBI chr 3:127,460,367...127,574,195
Ensembl chr 3:127,463,959...127,574,176

Dhx58

DEXH (Asp-Glu-X-His) box polypeptide 58

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr11:100,585,710...100,595,165
Ensembl chr11:100,585,710...100,595,097

Rigi

RNA sensor RIG-I

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 4:40,203,775...40,239,843
Ensembl chr 4:40,203,773...40,239,828

Tifa

TRAF-interacting protein with forkhead-associated domain

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 3:127,582,524...127,592,043
Ensembl chr 3:127,583,454...127,625,813

Fc receptor mediated inhibitory signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

leukocyte immunoglobulin-like receptor, subfamily B, member 4A

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr10:51,366,994...51,372,709
Ensembl chr10:51,356,708...51,372,709
Ensembl chr10:51,356,708...51,372,709

Lilrb4b

leukocyte immunoglobulin-like receptor, subfamily B, member 4B

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr10:51,356,708...51,362,425
Ensembl chr10:51,356,728...51,362,799

LYN proto-oncogene, Src family tyrosine kinase

involved_in

(MGI:3703139|PMID:16272347)

PMID:16272347

MGI:3703139

NCBI chr 4:3,676,865...3,791,612
Ensembl chr 4:3,678,115...3,813,122

Fc receptor mediated stimulatory signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fcer1g

Fc receptor, IgE, high affinity I, gamma polypeptide

acts_upstream_of_or_within
involved_in

(MGI:3029067|PMID:14764707)
(MGI:6201960|PMID:21873635)

PMID:14764707 PMID:21873635

MGI:3029067 MGI:6201960

NCBI chr 1:171,057,141...171,061,918
Ensembl chr 1:171,057,141...171,061,934

LYN proto-oncogene, Src family tyrosine kinase

involved_in

(MGI:3703139|PMID:16272347)
(MGI:6201960|PMID:21873635)

PMID:16272347 PMID:21873635

MGI:3703139 MGI:6201960

NCBI chr 4:3,676,865...3,791,612
Ensembl chr 4:3,678,115...3,813,122

Fc receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Kit

KIT proto-oncogene receptor tyrosine kinase

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382

Pigr

polymeric immunoglobulin receptor

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:130,754,421...130,779,986
Ensembl chr 1:130,754,421...130,779,986

Fc-epsilon receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fcer1g

Fc receptor, IgE, high affinity I, gamma polypeptide

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:171,057,141...171,061,918
Ensembl chr 1:171,057,141...171,061,934

Fer

fer (fms/fps related) protein kinase

involved_in

PMID:12192036 PMID:21873635

(MGI:6201960|PMID:21873635)
(MGI:2385502|PMID:12192036)

GO_Central
UniProt

MGI:2385502 MGI:6201960

NCBI chr17:64,136,945...64,453,515
Ensembl chr17:64,170,057...64,446,491

Ms4a2

membrane-spanning 4-domains, subfamily A, member 2

involved_in

GO_REF:0000002 MGI:2152098

NCBI chr19:11,592,881...11,601,154
Ensembl chr19:11,592,887...11,601,083

Fc-gamma receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd247

CD247 antigen

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:165,607,514...165,698,722
Ensembl chr 1:165,616,250...165,704,846

Clec4d

C-type lectin domain family 4, member d

acts_upstream_of_or_within

(MGI:5525050|PMID:23602766)

PMID:23602766

MGI:5525050

NCBI chr 6:123,239,066...123,252,227
Ensembl chr 6:123,239,070...123,252,224

Clec4e

C-type lectin domain family 4, member e

acts_upstream_of_or_within

(MGI:5525050|PMID:23602766)

PMID:23602766

MGI:5525050

NCBI chr 6:123,258,748...123,266,830
Ensembl chr 6:123,258,748...123,266,829

Fcer1g

Fc receptor, IgE, high affinity I, gamma polypeptide

acts_upstream_of_or_within
involved_in

(MGI:5525050|PMID:23602766)
(MGI:6201960|PMID:21873635)

PMID:21873635 PMID:23602766

MGI:5525050 MGI:6201960

NCBI chr 1:171,057,141...171,061,918
Ensembl chr 1:171,057,141...171,061,934

Fcgr4

Fc receptor, IgG, low affinity IV

involved_in

(PMID:23024279)
(PMID:23024279), (PMID:8478617)

PMID:8478617 PMID:23024279

NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330

Lck

lymphocyte protein tyrosine kinase

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 4:129,442,137...129,467,434
Ensembl chr 4:129,442,137...129,467,434

Oscar

osteoclast associated receptor

acts_upstream_of_or_within

(MGI:5297759|PMID:21841309)

PMID:21841309

MGI:5297759

NCBI chr 7:3,612,812...3,619,156
Ensembl chr 7:3,612,812...3,619,156

Fc-gamma receptor signaling pathway involved in phagocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fc receptor, IgG, low affinity IIb

involved_in

(PMID:2142460)

PMID:2142460

NCBI chr 1:170,788,127...170,803,691
Ensembl chr 1:170,786,186...170,804,116

Myo1g

myosin IG

involved_in

(MGI:5586792|PMID:23038771)

PMID:23038771

MGI:5586792

NCBI chr11:6,456,548...6,470,960
Ensembl chr11:6,456,548...6,470,965

helper T cell enhancement of adaptive immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd4

CD4 antigen

involved_in

(MGI:1933768|PMID:1832488)

PMID:1832488

MGI:1933768

NCBI chr 6:124,841,656...124,865,210
Ensembl chr 6:124,841,655...124,865,184

immune response-activating cell surface receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bag6

BCL2-associated athanogene 6

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr17:35,354,132...35,366,297
Ensembl chr17:35,354,154...35,366,298

Mill2

MHC I like leukocyte 2

involved_in

(PMID:11491531)

PMID:11491531

NCBI chr 7:18,573,878...18,603,621
Ensembl chr 7:18,573,891...18,599,327

Ncr3-ps

natural cytotoxicity triggering receptor 3, pseudogene

involved_in

(PMID:18852879)

PMID:18852879

NCBI chr17:35,399,512...35,403,785
Ensembl chr17:35,399,511...35,403,638

immune response-activating signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Zc3h12a

zinc finger CCCH type containing 12A

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 4:125,012,207...125,021,674
Ensembl chr 4:125,012,216...125,021,633

immune response-inhibiting cell surface receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

H2-M3

histocompatibility 2, M region locus 3

involved_in

(PMID:20702625)

PMID:20702625

NCBI chr17:37,581,094...37,585,376
Ensembl chr17:37,581,111...37,585,375

immune response-inhibiting signal transduction

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd33

CD33 molecule

involved_in

(PMID:10887109)

PMID:10887109

NCBI chr 7:43,176,823...43,186,679
Ensembl chr 7:43,173,640...43,193,852

Il20rb

interleukin 20 receptor beta

acts_upstream_of_or_within

(MGI:3827040|PMID:19124723)

PMID:19124723

MGI:3827040

NCBI chr 9:100,339,772...100,368,526
Ensembl chr 9:100,339,772...100,368,841

immune response-regulating cell surface receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Btla

B and T lymphocyte associated

acts_upstream_of_or_within
involved_in

(MGI:3521631|PMID:15568026)
(MGI:6201960|PMID:21873635)

PMID:15568026 PMID:21873635

MGI:3521631 MGI:6201960

NCBI chr16:45,043,121...45,073,258
Ensembl chr16:45,044,678...45,078,033

Cd40

CD40 antigen

acts_upstream_of_or_within
involved_in

(MGI:3051177|PMID:15240714)
(MGI:6201960|PMID:21873635)

PMID:15240714 PMID:21873635

MGI:3051177 MGI:6201960

NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868

Fpr2

formyl peptide receptor 2

involved_in

(PMID:25505240)

PMID:25505240

NCBI chr17:18,108,086...18,114,214
Ensembl chr17:18,108,086...18,114,214

LYN proto-oncogene, Src family tyrosine kinase

involved_in

(MGI:894972|PMID:9252121)

PMID:9252121

MGI:894972

NCBI chr 4:3,676,865...3,791,612
Ensembl chr 4:3,678,115...3,813,122

vav 1 oncogene

NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031

immune response-regulating signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ctsh

cathepsin H

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 9:89,936,320...89,958,148
Ensembl chr 9:89,936,205...89,958,142

Lat2

linker for activation of T cells family, member 2

involved_in

GO_REF:0000002 MGI:2152098

NCBI chr 5:134,628,957...134,648,637
Ensembl chr 5:134,628,876...134,643,879

innate immune response-activating signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Tlr4

toll-like receptor 4

involved_in

PMID:19226379

GO_REF:0000096 MGI:4417868 RGD:2312509

NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521

lymphocyte costimulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

interleukin 6

NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979

MDA-5 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ifih1

interferon induced with helicase C domain 1

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 2:62,426,137...62,476,599
Ensembl chr 2:62,426,142...62,476,599

Oas3

2'-5' oligoadenylate synthetase 3

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 5:120,891,163...120,915,755
Ensembl chr 5:120,891,163...120,915,726

MyD88-dependent toll-like receptor 4 signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Lrrfip2

leucine rich repeat (in FLII) interacting protein 2

acts_upstream_of_or_within

(MGI:3836337|PMID:19265123)

PMID:19265123

MGI:3836337

NCBI chr 9:110,946,614...111,054,736
Ensembl chr 9:110,946,660...111,054,736

MyD88-dependent toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hmgb1

high mobility group box 1

involved_in

(PMID:14660645)

PMID:14660645

NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299

Hspd1

heat shock protein 1 (chaperonin)

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402

Irak2

interleukin-1 receptor-associated kinase 2

involved_in

GO_REF:0000002 MGI:2152098

NCBI chr 6:113,615,428...113,671,987
Ensembl chr 6:113,615,428...113,671,987

Irak3

interleukin-1 receptor-associated kinase 3

involved_in

GO_REF:0000002 MGI:2152098

NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035

Myd88

myeloid differentiation primary response gene 88

acts_upstream_of_or_within

IMP
IGI

(MGI:2670551|PMID:12872135)
(MGI:3028810|PMID:14764662)
(MGI:3042099|PMID:12719478)

PMID:12719478 PMID:12872135 PMID:14764662

MGI:2670551 MGI:3028810 MGI:3042099

NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477

Reg3g

regenerating islet-derived 3 gamma

involved_in

(MGI:3760234|PMID:17635956)

PMID:17635956

MGI:3760234

NCBI chr 6:78,443,252...78,445,857
Ensembl chr 6:78,443,252...78,445,855

Tlr1

toll-like receptor 1

involved_in

GO_REF:0000002 MGI:2152098

NCBI chr 5:65,082,023...65,090,945
Ensembl chr 5:65,082,022...65,090,906

Tlr13

toll-like receptor 13

acts_upstream_of_or_within

(MGI:4941102|PMID:21131352)

PMID:21131352

MGI:4941102

NCBI chr X:105,186,881...105,204,099
Ensembl chr X:105,186,810...105,204,099

Tlr2

toll-like receptor 2

acts_upstream_of_or_within

(MGI:3042099|PMID:12719478)

PMID:12719478

MGI:3042099

NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074

Tlr4

toll-like receptor 4

involved_in

IGI
ISO

(MGI:4438693|PMID:20037584)

ARUK-UCL
MGI

PMID:20037584

GO_REF:0000096 MGI:4438693 MGI:4834177

NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521

Tlr5

toll-like receptor 5

involved_in

GO_REF:0000002 MGI:2152098

NCBI chr 1:182,782,317...182,804,010
Ensembl chr 1:182,782,353...182,804,010

Tlr6

toll-like receptor 6

involved_in

IGI
ISO

(MGI:4438693|PMID:20037584)

ARUK-UCL
MGI

PMID:20037584

GO_REF:0000096 MGI:4438693 MGI:4834177

NCBI chr 5:65,109,379...65,128,387
Ensembl chr 5:65,109,374...65,117,440

Tlr7

toll-like receptor 7

involved_in

GO_REF:0000002 MGI:2152098

NCBI chr X:166,086,376...166,113,570
Ensembl chr X:166,087,925...166,113,554

Tlr8

toll-like receptor 8

involved_in

GO_REF:0000002 MGI:2152098

NCBI chr X:166,024,119...166,047,325
Ensembl chr X:166,025,692...166,047,325

Tlr9

toll-like receptor 9

involved_in

IPI

(MGI:3826712|PMID:18820679)

PMID:18820679

MGI:3826712

NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082

Tnip1

TNFAIP3 interacting protein 1

involved_in

(MGI:5305352|PMID:22011580)

PMID:22011580

MGI:5305352

NCBI chr11:54,801,613...54,853,766
Ensembl chr11:54,801,611...54,853,743

MyD88-independent toll-like receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Lrrfip2

leucine rich repeat (in FLII) interacting protein 2

acts_upstream_of_or_within

(MGI:3836337|PMID:19265123)

PMID:19265123

MGI:3836337

NCBI chr 9:110,946,614...111,054,736
Ensembl chr 9:110,946,660...111,054,736

Ticam1

TIR domain containing adaptor molecule 1

acts_upstream_of_or_within

(MGI:2669022|PMID:12855817)
(MGI:2670551|PMID:12872135)

PMID:12855817 PMID:12872135

MGI:2669022 MGI:2670551

NCBI chr17:56,576,462...56,583,767
Ensembl chr17:56,576,319...56,583,786

Tlr3

toll-like receptor 3

involved_in

GO_REF:0000002 MGI:2152098

NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117

Tnip3

TNFAIP3 interacting protein 3

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 6:65,567,382...65,611,024
Ensembl chr 6:65,502,297...65,611,024

natural killer cell inhibitory signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Clec12b

C-type lectin domain family 12, member B

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 6:129,352,476...129,404,597
Ensembl chr 6:129,352,478...129,362,837

Klrc1

killer cell lectin-like receptor subfamily C, member 1

involved_in

(PMID:9485206)

PMID:9485206

NCBI chr 6:129,642,978...129,659,815
Ensembl chr 6:129,642,978...129,655,936

Sh2d1b1

SH2 domain containing 1B1

acts_upstream_of_or_within

(MGI:3639618|PMID:16127454)

PMID:16127454

MGI:3639618

NCBI chr 1:170,104,887...170,114,338
Ensembl chr 1:170,104,889...170,114,338

negative regulation of activated T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Arg1

arginase, liver

involved_in

(MGI:5908339|PMID:19360123)

PMID:19360123

MGI:5908339

NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382

Btn1a1

butyrophilin, subfamily 1, member A1

involved_in

(MGI:4453380|PMID:20208008)

PMID:20208008

MGI:4453380

NCBI chr13:23,641,154...23,650,084
Ensembl chr13:23,641,162...23,650,071

Btn2a2

butyrophilin, subfamily 2, member A2

acts_upstream_of_or_within
involved_in

(MGI:5520006|PMID:23589618)
(MGI:4453380|PMID:20208008)

PMID:20208008 PMID:23589618

MGI:4453380 MGI:5520006

NCBI chr13:23,661,219...23,673,028
Ensembl chr13:23,661,846...23,673,027

Casp3

caspase 3

acts_upstream_of_or_within

(MGI:2677082|PMID:12970760)

PMID:12970760

MGI:2677082

NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724

Cd274

CD274 antigen

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495

Crtam

cytotoxic and regulatory T cell molecule

involved_in

(MGI:3834299|PMID:18329370)

PMID:18329370

MGI:3834299

NCBI chr 9:40,884,094...40,915,924
Ensembl chr 9:40,880,987...40,915,924

Ido1

indoleamine 2,3-dioxygenase 1

acts_upstream_of_or_within

(MGI:3776720|PMID:18077788)

PMID:18077788

MGI:3776720

NCBI chr 8:25,074,149...25,086,968
Ensembl chr 8:25,074,152...25,087,025

Laptm5

lysosomal-associated protein transmembrane 5

involved_in

(MGI:3803048|PMID:18619870)

PMID:18619870

MGI:3803048

NCBI chr 4:130,640,627...130,663,459
Ensembl chr 4:130,640,436...130,663,452

Lgals9

lectin, galactose binding, soluble 9

involved_in

(PMID:23817958)

PMID:23817958

NCBI chr11:78,853,805...78,875,750
Ensembl chr11:78,853,800...78,875,772

leukocyte immunoglobulin-like receptor, subfamily B, member 4A

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr10:51,366,994...51,372,709
Ensembl chr10:51,356,708...51,372,709
Ensembl chr10:51,356,708...51,372,709

Lilrb4b

leukocyte immunoglobulin-like receptor, subfamily B, member 4B

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr10:51,356,708...51,362,425
Ensembl chr10:51,356,728...51,362,799

Lrrc32

leucine rich repeat containing 32

acts_upstream_of_or_within

(MGI:3807624|PMID:18628982)

PMID:18628982

MGI:3807624

NCBI chr 7:98,138,515...98,151,038
Ensembl chr 7:98,138,490...98,151,388

Mir181c

microRNA 181c

acts_upstream_of

(PMID:21112091)

PMID:21112091

NCBI chr 8:84,905,502...84,905,590
Ensembl chr 8:84,905,502...84,905,590

Pdcd1lg2

programmed cell death 1 ligand 2

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr19:29,388,319...29,450,327
Ensembl chr19:29,388,319...29,448,561

Prkar1a

protein kinase, cAMP dependent regulatory, type I, alpha

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr11:109,539,849...109,560,489
Ensembl chr11:109,540,231...109,560,482

Prnp

prion protein

involved_in

(MGI:4943618|PMID:20145049)

PMID:20145049

MGI:4943618

NCBI chr 2:131,751,848...131,780,356
Ensembl chr 2:131,751,848...131,780,349

Rc3h1

RING CCCH (C3H) domains 1

involved_in

(MGI:5284769|PMID:18172933)

PMID:18172933

MGI:5284769

NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548

Scrib

scribbled planar cell polarity

involved_in

(MGI:3834299|PMID:18329370)

PMID:11471050 PMID:17237428 PMID:21873635

PMID:18329370

MGI:3834299

NCBI chr15:75,919,011...75,941,633
Ensembl chr15:75,919,007...75,941,633

negative regulation of activation of membrane attack complex

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd59a

CD59a antigen

involved_in
acts_upstream_of_or_within

IBA
ISO
IDA
IMP

(MGI:6201960|PMID:21873635)
(MGI:2148385|PMID:11471050)
(MGI:3828358|PMID:17237428)

GO_Central
MGI
BHF-UCL

GO_REF:0000096 MGI:2148385 MGI:3828358 MGI:4417868 MGI:6201960

NCBI chr 2:103,926,101...103,945,755
Ensembl chr 2:103,926,146...103,945,699

Cd59b

CD59b antigen

acts_upstream_of_or_within
involved_in

IDA
ISO
IBA

(MGI:1888643|PMID:10946279), (MGI:2148385|PMID:11471050)
(MGI:6201960|PMID:21873635)

MGI
RGD
GO_Central

PMID:10946279 PMID:11471050 PMID:15843577 PMID:21873635

GO_REF:0000096 MGI:1888643 MGI:2148385 MGI:4417868 MGI:6201960 RGD:1600482

NCBI chr 2:103,900,127...103,920,619
Ensembl chr 2:103,900,194...103,921,532

negative regulation of activation-induced cell death of T cells

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fadd

Fas (TNFRSF6)-associated via death domain

involved_in

(MGI:5291865|PMID:21876153)

PMID:21876153

MGI:5291865

NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200

Gpam

glycerol-3-phosphate acyltransferase, mitochondrial

acts_upstream_of_or_within

(MGI:3826295|PMID:18971390)

PMID:18971390

MGI:3826295

NCBI chr19:55,056,067...55,115,751
Ensembl chr19:55,055,700...55,115,670

Tnfrsf4

tumor necrosis factor receptor superfamily, member 4

involved_in

(MGI:2150820|PMID:11567634)

PMID:11567634

MGI:2150820

NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069

Tnfsf4

tumor necrosis factor (ligand) superfamily, member 4

involved_in

(MGI:2150820|PMID:11567634)

PMID:11567634

MGI:2150820

NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981

Tsc22d3

TSC22 domain family, member 3

acts_upstream_of_or_within
involved_in

(MGI:1101744|PMID:9430225)
(MGI:6201960|PMID:21873635)

PMID:9430225 PMID:21873635

MGI:1101744 MGI:6201960

NCBI chr X:139,440,277...139,501,271
Ensembl chr X:139,440,277...139,501,408

negative regulation of acute inflammatory response to antigenic stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adcyap1

adenylate cyclase activating polypeptide 1

involved_in

PMID:17698245

GO_REF:0000096 MGI:4417868 RGD:2325282

NCBI chr17:93,505,673...93,513,969
Ensembl chr17:93,506,445...93,513,965

Fc receptor, IgG, low affinity IIb

acts_upstream_of_or_within

(MGI:3608295|PMID:12385742)

PMID:12385742

MGI:3608295

NCBI chr 1:170,788,127...170,803,691
Ensembl chr 1:170,786,186...170,804,116

Npy

neuropeptide Y

involved_in

PMID:18805447

GO_REF:0000096 MGI:4417868 RGD:10448932

NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487

Npy5r

neuropeptide Y receptor Y5

involved_in

PMID:18805447

GO_REF:0000096 MGI:4417868 RGD:10448932

NCBI chr 8:67,132,617...67,140,746
Ensembl chr 8:67,132,617...67,140,780

Selenos

selenoprotein S

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 7:65,729,397...65,739,153
Ensembl chr 7:65,729,397...65,739,153

negative regulation of adaptive immune memory response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd160

CD160 antigen

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 3:96,706,079...96,736,667
Ensembl chr 3:96,706,079...96,736,667

Tnfrsf14

tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 4:155,002,944...155,013,077
Ensembl chr 4:155,006,390...155,013,020

negative regulation of adaptive immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Alox15

arachidonate 15-lipoxygenase

involved_in

(MGI:5436199|PMID:22503541)

PMID:22503541

MGI:5436199

NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857

Samsn1

SAM domain, SH3 domain and nuclear localization signals, 1

involved_in

(MGI:4437539|PMID:19923443)

PMID:19923443

MGI:4437539

NCBI chr16:75,655,682...75,706,154
Ensembl chr16:75,655,681...75,819,169

Trim27

tripartite motif-containing 27

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr13:21,363,570...21,378,893
Ensembl chr13:21,363,615...21,378,894

negative regulation of alpha-beta T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adora2a

adenosine A2a receptor

acts_upstream_of_or_within

(MGI:3822045|PMID:10069416)

PMID:10069416

MGI:3822045

NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618

Vsir

V-set immunoregulatory receptor

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr10:60,182,630...60,266,073
Ensembl chr10:60,182,630...60,208,463

negative regulation of alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gli3

GLI-Kruppel family member GLI3

involved_in

(MGI:4355451|PMID:19667090)

PMID:19667090

MGI:4355451

NCBI chr13:15,638,308...15,904,611
Ensembl chr13:15,637,820...15,904,611

Ihh

Indian hedgehog

involved_in

(MGI:3836494|PMID:19109233)

PMID:19109233

MGI:3836494

NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831

Shh

sonic hedgehog

acts_upstream_of_or_within

(MGI:1888832|PMID:10981962)

PMID:10981962

MGI:1888832

NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254

negative regulation of alpha-beta T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Btla

B and T lymphocyte associated

acts_upstream_of_or_within

(MGI:3521631|PMID:15568026)

PMID:15568026

MGI:3521631

NCBI chr16:45,043,121...45,073,258
Ensembl chr16:45,044,678...45,078,033

Clec4g

C-type lectin domain family 4, member g

acts_upstream_of_or_within

(MGI:5475030|PMID:23487419)

PMID:23487419

MGI:5475030

NCBI chr 8:3,757,066...3,770,695
Ensembl chr 8:3,757,064...3,770,651

Foxp3

forkhead box P3

acts_upstream_of_or_within

(MGI:3692513|PMID:16945588)

PMID:16945588

MGI:3692513

NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484

Tnfrsf14

tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 4:155,002,944...155,013,077
Ensembl chr 4:155,006,390...155,013,020

negative regulation of antibacterial peptide production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Spink5

serine peptidase inhibitor, Kazal type 5

involved_in

(MGI:3770082|PMID:17012259)

PMID:17012259

MGI:3770082

NCBI chr18:44,092,612...44,155,554
Ensembl chr18:44,096,302...44,155,568

negative regulation of antifungal innate immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fam3a

FAM3 metabolism regulating signaling molecule A

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr X:73,427,816...73,436,880
Ensembl chr X:73,428,325...73,436,878

Usp15

ubiquitin specific peptidase 15

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr10:122,940,911...123,032,924
Ensembl chr10:122,940,911...123,032,900

negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hfe

homeostatic iron regulator

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr13:23,886,017...23,894,837
Ensembl chr13:23,886,017...23,894,837

negative regulation of antigen processing and presentation of peptide antigen via MHC class I

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Tapbpl

TAP binding protein-like

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 6:125,200,890...125,208,823
Ensembl chr 6:125,200,896...125,208,823

negative regulation of antigen processing and presentation of peptide antigen via MHC class II

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

H2-Oa

histocompatibility 2, O region alpha locus

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr17:34,311,353...34,314,286
Ensembl chr17:34,311,314...34,314,208

H2-Ob

histocompatibility 2, O region beta locus

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr17:34,457,879...34,464,882
Ensembl chr17:34,457,877...34,473,388

negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Thbs1

thrombospondin 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614

negative regulation of B cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bank1

B cell scaffold protein with ankyrin repeats 1

involved_in
acts_upstream_of_or_within

IBA
IGI

(MGI:6201960|PMID:21873635)
(MGI:3665389|PMID:16546095)

PMID:16546095 PMID:21873635

MGI:3665389 MGI:6201960

NCBI chr 3:135,759,124...136,031,902
Ensembl chr 3:135,759,124...136,031,827

Btk

Bruton agammaglobulinemia tyrosine kinase

involved_in

PMID:25545336

GO_REF:0000096 MGI:4417868 RGD:151665128

NCBI chr X:133,443,083...133,484,366
Ensembl chr X:133,443,085...133,484,319

Fas

Fas (TNF receptor superfamily member 6)

acts_upstream_of_or_within

(MGI:55958|PMID:6610701)

PMID:6610701

MGI:55958

NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172

Foxj1

forkhead box J1

involved_in

(MGI:3589323|PMID:16002694)

PMID:16002694

MGI:3589323

NCBI chr11:116,221,530...116,226,331
Ensembl chr11:116,221,530...116,226,225

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

(MGI:1354084|PMID:10704460)

PMID:10704460

MGI:1354084

NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229

Laptm5

lysosomal-associated protein transmembrane 5

involved_in

(MGI:4460047|PMID:20519653)

PMID:20519653

MGI:4460047

NCBI chr 4:130,640,627...130,663,459
Ensembl chr 4:130,640,436...130,663,452

Mir185

microRNA 185

acts_upstream_of

(PMID:24803541)

PMID:24803541

NCBI chr16:18,145,265...18,145,329
Ensembl chr16:18,145,265...18,145,329

Samsn1

SAM domain, SH3 domain and nuclear localization signals, 1

involved_in

(MGI:4437539|PMID:19923443)
(MGI:6201960|PMID:21873635)

PMID:19923443 PMID:21873635

MGI:4437539 MGI:6201960

NCBI chr16:75,655,682...75,706,154
Ensembl chr16:75,655,681...75,819,169

Tbc1d10c

TBC1 domain family, member 10c

acts_upstream_of_or_within

IGI
IMP

(MGI:5576870|PMID:23109291)

PMID:23109291

MGI:5576870

NCBI chr19:4,234,356...4,241,194
Ensembl chr19:4,233,410...4,241,283

Tnfaip3

tumor necrosis factor, alpha-induced protein 3

involved_in

(MGI:4946158|PMID:21088135)

PMID:21088135

MGI:4946158

NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405

negative regulation of B cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Flt3

FMS-like tyrosine kinase 3

acts_upstream_of_or_within

(MGI:3623701|PMID:16618805)

PMID:16618805

MGI:3623701

NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299

Hmgb3

high mobility group box 3

acts_upstream_of_or_within

(MGI:2670545|PMID:12714519)

PMID:12714519

MGI:2670545

NCBI chr X:70,599,523...70,604,279
Ensembl chr X:70,599,524...70,604,282

Id2

inhibitor of DNA binding 2

acts_upstream_of_or_within

(MGI:3805135|PMID:18523151)

PMID:18523151

MGI:3805135

NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139

Sfrp1

secreted frizzled-related protein 1

involved_in

ISO
IMP

(MGI:3814493|PMID:18941195)

PMID:18941195

GO_REF:0000096 MGI:3814493 MGI:4834177

NCBI chr 8:23,901,401...23,939,648
Ensembl chr 8:23,901,518...23,939,648

negative regulation of B cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Atm

ataxia telangiectasia mutated

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040

Btk

Bruton agammaglobulinemia tyrosine kinase

acts_upstream_of_or_within

(MGI:65977|PMID:7680896)

PMID:7680896

MGI:65977

NCBI chr X:133,443,083...133,484,366
Ensembl chr X:133,443,085...133,484,319

Btla

B and T lymphocyte associated

acts_upstream_of_or_within

(MGI:2665193|PMID:12796776)

PMID:12796776

MGI:2665193

NCBI chr16:45,043,121...45,073,258
Ensembl chr16:45,044,678...45,078,033

Casp3

caspase 3

acts_upstream_of_or_within

(MGI:2677082|PMID:12970760)

PMID:12970760

MGI:2677082

NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724

Cd24a

CD24a antigen

acts_upstream_of_or_within

(MGI:3757615|PMID:8920854)

PMID:8920854

MGI:3757615

NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261

CD300A molecule

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr11:114,780,006...114,792,772
Ensembl chr11:114,780,867...114,795,480

Cdkn2a

cyclin dependent kinase inhibitor 2A

involved_in

(MGI:3615850|PMID:15964995)

HGNC-UCL

PMID:15964995

MGI:3615850

NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890

Ctla4

cytotoxic T-lymphocyte-associated protein 4

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991

Fc receptor, IgG, low affinity IIb

acts_upstream_of_or_within

(MGI:3608295|PMID:12385742), (MGI:78617|PMID:8552190)

PMID:8552190 PMID:12385742

MGI:3608295 MGI:78617

NCBI chr 1:170,788,127...170,803,691
Ensembl chr 1:170,786,186...170,804,116

Ifi211

interferon activated gene 211

involved_in

(PMID:17875758)

PMID:17875758

NCBI chr 1:173,723,907...173,740,650
Ensembl chr 1:173,723,911...173,740,612

Il10

interleukin 10

acts_upstream_of_or_within

(MGI:892164|PMID:9184696)

PMID:9184696

MGI:892164

NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

(MGI:1354084|PMID:10704460)

PMID:10704460

MGI:1354084

NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229

LYN proto-oncogene, Src family tyrosine kinase

involved_in

(MGI:894972|PMID:9252121)
(MGI:6201960|PMID:21873635)

PMID:9252121 PMID:21873635

MGI:6201960 MGI:894972

NCBI chr 4:3,676,865...3,791,612
Ensembl chr 4:3,678,115...3,813,122

Mir185

microRNA 185

acts_upstream_of

(PMID:24803541)

PMID:24803541

NCBI chr16:18,145,265...18,145,329
Ensembl chr16:18,145,265...18,145,329

Pawr

PRKC, apoptosis, WT1, regulator

acts_upstream_of_or_within

(MGI:2675524|PMID:12970181)

PMID:12970181

MGI:2675524

NCBI chr10:108,168,050...108,250,708
Ensembl chr10:108,167,982...108,250,101

Pkn1

protein kinase N1

acts_upstream_of_or_within

(MGI:5467878|PMID:23223530)

PMID:23223530

MGI:5467878

NCBI chr 8:84,393,162...84,425,819
Ensembl chr 8:84,393,165...84,425,808

Prdm1

PR domain containing 1, with ZNF domain

acts_upstream_of_or_within

(MGI:3826899|PMID:18845144)

PMID:18845144

MGI:3826899

NCBI chr10:44,313,170...44,404,548
Ensembl chr10:44,313,173...44,404,497

Pten

phosphatase and tensin homolog

acts_upstream_of_or_within

(MGI:3586939|PMID:16027169)

PMID:16027169

MGI:3586939

NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560

Rc3h1

RING CCCH (C3H) domains 1

involved_in

(MGI:5284769|PMID:18172933)

PMID:18172933

MGI:5284769

NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548

Tnfrsf13b

tumor necrosis factor receptor superfamily, member 13b

acts_upstream_of_or_within
involved_in

(MGI:3051152|PMID:15240667)
(MGI:6201960|PMID:21873635)

PMID:15240667 PMID:21873635

MGI:3051152 MGI:6201960

NCBI chr11:61,017,567...61,040,435
Ensembl chr11:61,017,581...61,040,198

Tnfrsf21

tumor necrosis factor receptor superfamily, member 21

involved_in

(MGI:3628730|PMID:12515813)
(MGI:6201960|PMID:21873635)

PMID:12515813 PMID:21873635

MGI:3628730 MGI:6201960

NCBI chr17:43,327,446...43,400,079
Ensembl chr17:43,327,446...43,400,080

Tsc2

TSC complex subunit 2

acts_upstream_of_or_within

(MGI:3586939|PMID:16027169)

PMID:21727189 PMID:21873635

PMID:16027169

MGI:3586939

NCBI chr17:24,814,790...24,851,607
Ensembl chr17:24,814,790...24,851,604

Tyrobp

TYRO protein tyrosine kinase binding protein

involved_in

IBA
IMP
ISO

(MGI:6201960|PMID:21873635)
(MGI:5295549|PMID:21727189)

GO_Central
UniProt
MGI

GO_REF:0000096 MGI:4834177 MGI:5295549 MGI:6201960

NCBI chr 7:30,113,207...30,117,007
Ensembl chr 7:30,113,185...30,117,010

negative regulation of B cell receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd22

CD22 antigen

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 7:30,564,829...30,579,767
Ensembl chr 7:30,564,827...30,579,767

CD300A molecule

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr11:114,780,006...114,792,772
Ensembl chr11:114,780,867...114,795,480

Fc receptor, IgG, low affinity IIb

involved_in

(PMID:24169826)

PMID:24169826

NCBI chr 1:170,788,127...170,803,691
Ensembl chr 1:170,786,186...170,804,116

Fcrl5

Fc receptor-like 5

acts_upstream_of_or_within

IDA
IGI

(MGI:5471851|PMID:23509253)

PMID:23509253

MGI:5471851

NCBI chr 3:87,343,084...87,407,985
Ensembl chr 3:87,343,080...87,407,985

Gps2

G protein pathway suppressor 2

involved_in

(MGI:5896692|PMID:28039360)

PMID:17640867 PMID:21873635

PMID:28039360

MGI:5896692

NCBI chr11:69,804,805...69,807,882
Ensembl chr11:69,804,714...69,807,417

Lpxn

leupaxin

involved_in

ISO
IDA
IBA

(MGI:3722965|PMID:17640867)
(MGI:6201960|PMID:21873635)

MGI
UniProt
GO_Central

GO_REF:0000096 MGI:3722965 MGI:4834177 MGI:6201960

NCBI chr19:12,773,251...12,811,177
Ensembl chr19:12,773,557...12,811,171

Mir34a

microRNA 34a

involved_in

(PMID:30111844)

PMID:30111844

NCBI chr 4:150,152,911...150,153,012
Ensembl chr 4:150,152,911...150,153,012

Plcl2

phospholipase C-like 2

acts_upstream_of_or_within

(MGI:2677607|PMID:14517301)

PMID:14517301

MGI:2677607

NCBI chr17:50,815,893...50,995,522
Ensembl chr17:50,816,431...50,995,512

negative regulation of CD4-positive, alpha-beta T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Skint2

selection and upkeep of intraepithelial T cells 2

acts_upstream_of_or_within

(MGI:3830586|PMID:17339463)

PMID:17339463

MGI:3830586

NCBI chr 4:112,470,795...112,509,445
Ensembl chr 4:112,414,391...112,509,445

Tarm1

T cell-interacting, activating receptor on myeloid cells 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 7:3,535,015...3,551,159
Ensembl chr 7:3,535,016...3,551,140

Twsg1

twisted gastrulation BMP signaling modulator 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr17:66,230,060...66,258,198
Ensembl chr17:66,228,967...66,258,221

negative regulation of CD4-positive, alpha-beta T cell costimulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd160

CD160 antigen

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 3:96,706,079...96,736,667
Ensembl chr 3:96,706,079...96,736,667

negative regulation of CD4-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cbfb

core binding factor beta

involved_in

(MGI:3772948|PMID:18258917)

PMID:18258917

MGI:3772948

NCBI chr 8:105,897,230...105,944,621
Ensembl chr 8:105,897,306...105,944,621

Hmgb1

high mobility group box 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299

Runx1

runt related transcription factor 1

involved_in

(MGI:3772948|PMID:18258917)

PMID:18258917

MGI:3772948

NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037

Runx3

runt related transcription factor 3

involved_in

(MGI:3772948|PMID:18258917)

PMID:18258917

MGI:3772948

NCBI chr 4:134,847,956...134,905,301
Ensembl chr 4:134,847,963...134,905,301

negative regulation of CD4-positive, alpha-beta T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Arg2

arginase type II

involved_in

(MGI:5908533|PMID:25009204)

PMID:25009204

MGI:5908533

NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075

Cblb

Casitas B-lineage lymphoma b

acts_upstream_of_or_within

(MGI:3038342|PMID:14973438)

PMID:14973438

MGI:3038342

NCBI chr16:51,851,593...52,028,410
Ensembl chr16:51,851,588...52,028,411

Cd274

CD274 antigen

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495

Cd44

CD44 antigen

involved_in

(MGI:5688819|PMID:25065622)

PMID:25065622

MGI:5688819

NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010

Foxp3

forkhead box P3

acts_upstream_of_or_within

(MGI:3697020|PMID:17028180)

PMID:17028180

MGI:3697020

NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484

Itch

itchy, E3 ubiquitin protein ligase

acts_upstream_of_or_within

(MGI:3038342|PMID:14973438)

PMID:14973438

MGI:3038342

NCBI chr 2:154,975,401...155,068,775
Ensembl chr 2:154,975,429...155,068,775

Lgals9

lectin, galactose binding, soluble 9

involved_in

PMID:21873635 PMID:25065622

(MGI:6201960|PMID:21873635)
(MGI:5688819|PMID:25065622)

GO_Central
UniProt

MGI:5688819 MGI:6201960

NCBI chr11:78,853,805...78,875,750
Ensembl chr11:78,853,800...78,875,772

Ndfip1

Nedd4 family interacting protein 1

acts_upstream_of_or_within

(MGI:3694584|PMID:17137798)

PMID:17137798

MGI:3694584

NCBI chr18:38,551,960...38,598,250
Ensembl chr18:38,543,449...38,598,356

Tarm1

T cell-interacting, activating receptor on myeloid cells 1

involved_in

(MGI:5908526|PMID:26311901)

PMID:26311901

MGI:5908526

NCBI chr 7:3,535,015...3,551,159
Ensembl chr 7:3,535,016...3,551,140

Tnfrsf14

tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)

acts_upstream_of_or_within

(MGI:3521631|PMID:15568026)

PMID:15568026

MGI:3521631

NCBI chr 4:155,002,944...155,013,077
Ensembl chr 4:155,006,390...155,013,020

Twsg1

twisted gastrulation BMP signaling modulator 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr17:66,230,060...66,258,198
Ensembl chr17:66,228,967...66,258,221

Vsir

V-set immunoregulatory receptor

involved_in
acts_upstream_of_or_within

(MGI:5292805|PMID:21383057)

PMID:21383057

GO_REF:0000096 MGI:4834177 MGI:5292805

NCBI chr10:60,182,630...60,266,073
Ensembl chr10:60,182,630...60,208,463

Xcl1

chemokine (C motif) ligand 1

involved_in

(PMID:10887101)

PMID:10887101

NCBI chr 1:164,759,213...164,763,091
Ensembl chr 1:164,759,213...164,763,096

negative regulation of CD8-positive, alpha-beta T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd274

CD274 antigen

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495

Hfe

homeostatic iron regulator

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr13:23,886,017...23,894,837
Ensembl chr13:23,886,017...23,894,837

Skint2

selection and upkeep of intraepithelial T cells 2

acts_upstream_of_or_within

(MGI:3830586|PMID:17339463)

PMID:17339463

MGI:3830586

NCBI chr 4:112,470,795...112,509,445
Ensembl chr 4:112,414,391...112,509,445

negative regulation of CD8-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Slc4a2

solute carrier family 4 (anion exchanger), member 2

involved_in

(MGI:6840447|PMID:24515893)

PMID:24515893

MGI:6840447

NCBI chr 5:24,628,939...24,645,945
Ensembl chr 5:24,628,835...24,645,948

Socs1

suppressor of cytokine signaling 1

involved_in

(MGI:6140589|PMID:24880459)

PMID:24880459

MGI:6140589

NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400

Zbtb7b

zinc finger and BTB domain containing 7B

involved_in

(MGI:5446998|PMID:22730529), (MGI:6140589|PMID:24880459)

PMID:22730529 PMID:24880459

MGI:5446998 MGI:6140589

NCBI chr 3:89,284,951...89,300,980
Ensembl chr 3:89,284,951...89,302,083

negative regulation of CD8-positive, alpha-beta T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Slc4a2

solute carrier family 4 (anion exchanger), member 2

involved_in

(MGI:6840447|PMID:24515893)

PMID:24515893

MGI:6840447

NCBI chr 5:24,628,939...24,645,945
Ensembl chr 5:24,628,835...24,645,948

Vsir

V-set immunoregulatory receptor

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr10:60,182,630...60,266,073
Ensembl chr10:60,182,630...60,208,463

negative regulation of cellular extravasation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abr

active BCR-related gene

involved_in

(MGI:5475443|PMID:23152932)

CACAO

PMID:23152932

MGI:5475443

NCBI chr11:76,307,558...76,468,565
Ensembl chr11:76,307,560...76,514,384

Bcr

BCR activator of RhoGEF and GTPase

involved_in

(MGI:5475443|PMID:23152932)

CACAO

PMID:23152932

MGI:5475443

NCBI chr10:74,896,384...75,020,755
Ensembl chr10:74,896,424...75,020,753

Il27ra

interleukin 27 receptor, alpha

involved_in

(MGI:5581894|PMID:22927332)

PMID:22927332

MGI:5581894

NCBI chr 8:84,756,915...84,769,250
Ensembl chr 8:84,756,923...84,769,218

Mir146

microRNA 146

acts_upstream_of

(PMID:31926946)

PMID:31926946

NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288

negative regulation of chronic inflammatory response to antigenic stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Il10

interleukin 10

acts_upstream_of_or_within

(MGI:3774790|PMID:12452830)

PMID:12452830

MGI:3774790

NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711

negative regulation of complement activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd55

CD55 molecule, decay accelerating factor for complement

involved_in

PMID:10929073

GO_REF:0000096 MGI:4417868 MGI:4834177 RGD:2326180

NCBI chr 1:130,357,526...130,392,746
Ensembl chr 1:130,366,764...130,390,481

Cd55b

CD55 molecule, decay accelerating factor for complement B

involved_in

GO_REF:0000096 MGI:4417868 MGI:4834177

NCBI chr 1:130,316,263...130,350,831
Ensembl chr 1:130,316,274...130,350,746

Cd59a

CD59a antigen

involved_in

(MGI:3828358|PMID:17237428)

PMID:17237428

MGI:3828358

NCBI chr 2:103,926,101...103,945,755
Ensembl chr 2:103,926,146...103,945,699

Cd59b

CD59b antigen

acts_upstream_of_or_within

(MGI:1888643|PMID:10946279)

PMID:10946279

MGI:1888643

NCBI chr 2:103,900,127...103,920,619
Ensembl chr 2:103,900,194...103,921,532

complement component (3b/4b) receptor 1-like

acts_upstream_of_or_within
involved_in

PMID:10642554 PMID:11861390

(MGI:1351571|PMID:10642554)

MGI
RGD

GO_REF:0000096 MGI:1351571 MGI:4417868 RGD:625470

NCBI chr 1:194,781,019...194,813,878
Ensembl chr 1:194,779,690...194,813,894

Masp1

mannan-binding lectin serine peptidase 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr16:23,261,778...23,340,127
Ensembl chr16:23,268,167...23,339,565

Serping1

serine (or cysteine) peptidase inhibitor, clade G, member 1

involved_in

GO_REF:0000002 MGI:2152098

NCBI chr 2:84,595,704...84,605,778
Ensembl chr 2:84,595,731...84,605,788

negative regulation of complement activation, alternative pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd46

CD46 antigen, complement regulatory protein

involved_in

(PMID:9029106)

AgBase

PMID:9029106

NCBI chr 1:194,721,279...194,781,149
Ensembl chr 1:194,719,134...194,774,557

Susd4

sushi domain containing 4

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 1:182,591,609...182,724,161
Ensembl chr 1:182,591,425...182,724,156

Vsig4

V-set and immunoglobulin domain containing 4

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr X:95,290,807...95,337,044
Ensembl chr X:95,290,809...95,337,044

negative regulation of complement activation, classical pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

C4bp

complement component 4 binding protein

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 1:130,563,658...130,589,394
Ensembl chr 1:130,562,510...130,589,369

Cd46

CD46 antigen, complement regulatory protein

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 1:194,721,279...194,781,149
Ensembl chr 1:194,719,134...194,774,557

complement component (3b/4b) receptor 1-like

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 1:194,781,019...194,813,878
Ensembl chr 1:194,779,690...194,813,894

Cr2

complement receptor 2

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 1:194,819,120...194,859,096
Ensembl chr 1:194,819,119...194,859,024

Susd4

sushi domain containing 4

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 1:182,591,609...182,724,161
Ensembl chr 1:182,591,425...182,724,156

Svep1

sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1

involved_in

(MGI:6201960|PMID:21873635)

NCBI chr 4:58,042,796...58,206,596
Ensembl chr 4:58,042,442...58,206,859

Zp3r

zona pellucida 3 receptor

involved_in

(MGI:6201960|PMID:21873635)

GO_REF:0000096 MGI:4834177 MGI:6201960

NCBI chr 1:130,474,847...130,557,371
Ensembl chr 1:130,504,450...130,557,358

negative regulation of complement activation, lectin pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

A2m

alpha-2-macroglobulin

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186

Serping1

serine (or cysteine) peptidase inhibitor, clade G, member 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 2:84,595,704...84,605,778
Ensembl chr 2:84,595,731...84,605,788

negative regulation of cytokine production involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Angpt1

angiopoietin 1

acts_upstream_of_or_within

(MGI:4437182|PMID:20060382)

PMID:20060382

MGI:4437182

NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373

Apoa1

apolipoprotein A-I

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764

Apoa2

apolipoprotein A-II

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948

Il10

interleukin 10

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711

Tnf

tumor necrosis factor

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983

negative regulation of cytotoxic T cell degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ceacam1

CEA cell adhesion molecule 1

involved_in

(PMID:18424730)

PMID:18424730

NCBI chr 7:25,161,127...25,177,072
Ensembl chr 7:25,161,132...25,177,028

Nckap1l

NCK associated protein 1 like

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237

negative regulation of cytotoxic T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

leukocyte immunoglobulin-like receptor, subfamily B, member 4A

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr10:51,366,994...51,372,709
Ensembl chr10:51,356,708...51,372,709
Ensembl chr10:51,356,708...51,372,709

Lilrb4b

leukocyte immunoglobulin-like receptor, subfamily B, member 4B

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr10:51,356,708...51,362,425
Ensembl chr10:51,356,728...51,362,799

negative regulation of dendritic cell antigen processing and presentation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd68

CD68 antigen

involved_in

(MGI:5285055|PMID:21572087)

PMID:21572087

MGI:5285055

NCBI chr11:69,555,039...69,556,996
Ensembl chr11:69,555,039...69,556,979

Fgl2

fibrinogen-like protein 2

acts_upstream_of_or_within

(MGI:6188369|PMID:29341118)

PMID:29341118

MGI:6188369

NCBI chr 5:21,577,671...21,583,384
Ensembl chr 5:21,577,640...21,583,372

Thbs1

thrombospondin 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614

negative regulation of dendritic cell chemotaxis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Slamf8

SLAM family member 8

acts_upstream_of_or_within

(MGI:5752697|PMID:25799045)

PMID:25799045

MGI:5752697

NCBI chr 1:172,408,944...172,418,482
Ensembl chr 1:172,409,325...172,418,135

negative regulation of dendritic cell cytokine production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Jak3

Janus kinase 3

involved_in

(MGI:3719947|PMID:16020505)

PMID:16020505

MGI:3719947

NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219

negative regulation of dendritic cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

H2-M3

histocompatibility 2, M region locus 3

involved_in

(PMID:20702625)

PMID:20702625

NCBI chr17:37,581,094...37,585,376
Ensembl chr17:37,581,111...37,585,375

Tmem176a

transmembrane protein 176A

acts_upstream_of_or_within

(MGI:4835631|PMID:20501748)

PMID:20501748

MGI:4835631

NCBI chr 6:48,818,417...48,822,298
Ensembl chr 6:48,817,853...48,824,005

Tmem176b

transmembrane protein 176B

acts_upstream_of_or_within
involved_in

(MGI:4835631|PMID:20501748)
(MGI:6201960|PMID:21873635)

PMID:20501748 PMID:21873635

MGI:4835631 MGI:6201960

NCBI chr 6:48,810,745...48,818,363
Ensembl chr 6:48,810,752...48,818,430

Zbtb46

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

(MGI:5320487|PMID:22615127)

PMID:22615127

MGI:5320487

NCBI chr 2:181,012,105...181,134,776
Ensembl chr 2:181,029,555...181,101,219

negative regulation of eosinophil activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD300A molecule

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr11:114,780,006...114,792,772
Ensembl chr11:114,780,867...114,795,480

negative regulation of eosinophil degranulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ccr2

chemokine (C-C motif) receptor 2

involved_in

(MGI:3699670|PMID:14662900)

PMID:14662900

MGI:3699670

NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594

negative regulation of eosinophil extravasation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ptger4

prostaglandin E receptor 4 (subtype EP4)

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668

negative regulation of eosinophil migration

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD300A molecule

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr11:114,780,006...114,792,772
Ensembl chr11:114,780,867...114,795,480

negative regulation of erythrocyte clearance

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd24a

CD24a antigen

acts_upstream_of_or_within

(MGI:2179980|PMID:9028339)

PMID:9028339

MGI:2179980

NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261

Ypel4

yippee like 4

acts_upstream_of_or_within

(MGI:6754953|PMID:34354145)

PMID:34354145

MGI:6754953

NCBI chr 2:84,564,355...84,568,999
Ensembl chr 2:84,564,402...84,568,999

negative regulation of erythrocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gas2l1

growth arrest-specific 2 like 1

involved_in

ISS
ISO

(MGI:5306571|PMID:19375645)

PMID:19375645

GO_REF:0000096 MGI:4834177 MGI:5306571

NCBI chr11:5,004,131...5,015,351
Ensembl chr11:5,004,132...5,015,327

Hoxa5

homeobox A5

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 6:52,178,734...52,181,567
Ensembl chr 6:52,178,734...52,181,567

Hspa9

heat shock protein 9

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410

Klf13

Kruppel-like factor 13

involved_in

(MGI:3796470|PMID:18285334)

PMID:18285334

MGI:3796470

NCBI chr 7:63,536,099...63,588,663
Ensembl chr 7:63,536,099...63,588,663

Ldb1

LIM domain binding 1

involved_in

(MGI:3700453|PMID:9391090)

PMID:9391090

MGI:3700453

NCBI chr19:46,019,963...46,036,584
Ensembl chr19:46,020,009...46,033,653

Lmo2

LIM domain only 2

involved_in

(MGI:3700453|PMID:9391090)

PMID:9391090

MGI:3700453

NCBI chr 2:103,788,340...103,812,223
Ensembl chr 2:103,788,331...103,812,223

Mafb

v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 2:160,205,597...160,208,985
Ensembl chr 2:160,205,623...160,208,985

Stat5a

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

(MGI:1332382|PMID:10072077)

PMID:10072077

MGI:1332382

NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995

Stat5b

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

(MGI:1332382|PMID:10072077)

PMID:10072077

MGI:1332382

NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550

Ypel4

yippee like 4

acts_upstream_of_or_within

(MGI:6754953|PMID:34354145)

PMID:34354145

MGI:6754953

NCBI chr 2:84,564,355...84,568,999
Ensembl chr 2:84,564,402...84,568,999

Zfp36

zinc finger protein 36

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 7:28,076,209...28,078,653
Ensembl chr 7:28,076,209...28,079,678

Zfp36l1

zinc finger protein 36, C3H type-like 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr12:80,154,534...80,159,787
Ensembl chr12:80,154,528...80,159,787

negative regulation of establishment of T cell polarity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ripor2

RHO family interacting cell polarization regulator 2

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr13:24,685,369...24,917,789
Ensembl chr13:24,685,508...24,917,799

negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Appl1

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

involved_in

(MGI:6271154|PMID:25568335)

PMID:25568335

MGI:6271154

NCBI chr14:26,640,943...26,692,567
Ensembl chr14:26,640,945...26,693,189

Cd47

CD47 antigen (Rh-related antigen, integrin-associated signal transducer)

involved_in

GO_REF:0000096 MGI:4417868

NCBI chr16:49,671,691...49,732,799
Ensembl chr16:49,620,896...49,735,373

Pten

phosphatase and tensin homolog

involved_in

PMID:18056380

GO_REF:0000096 MGI:4417868 RGD:2292524

NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560

negative regulation of germinal center formation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Foxj1

forkhead box J1

involved_in

(MGI:3589323|PMID:16002694)

PMID:16002694

MGI:3589323

NCBI chr11:116,221,530...116,226,331
Ensembl chr11:116,221,530...116,226,225

Rc3h1

RING CCCH (C3H) domains 1

involved_in

(MGI:5284769|PMID:18172933)

PMID:18172933

MGI:5284769

NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548

negative regulation of granulocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adipoq

adiponectin, C1Q and collagen domain containing

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778

C1qc

complement component 1, q subcomponent, C chain

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 4:136,617,112...136,620,242
Ensembl chr 4:136,617,115...136,620,376

Ceacam1

CEA cell adhesion molecule 1

involved_in

(MGI:4837548|PMID:21029969)

PMID:21029969

MGI:4837548

NCBI chr 7:25,161,127...25,177,072
Ensembl chr 7:25,161,132...25,177,028

Cul4a

cullin 4A

acts_upstream_of_or_within

(MGI:3691926|PMID:12393421)

PMID:12393421

MGI:3691926

NCBI chr 8:13,155,623...13,197,940
Ensembl chr 8:13,155,621...13,197,940

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

(MGI:1266928|PMID:9620849)

PMID:9620849

MGI:1266928

NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229

Prdm16

PR domain containing 16

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 4:154,400,579...154,721,851
Ensembl chr 4:154,400,582...154,721,330

Rara

retinoic acid receptor, alpha

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768

Runx1

runt related transcription factor 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037

Zbtb46

zinc finger and BTB domain containing 46

acts_upstream_of_or_within

(MGI:5320487|PMID:22615127)

PMID:22615127

MGI:5320487

NCBI chr 2:181,012,105...181,134,776
Ensembl chr 2:181,029,555...181,101,219

negative regulation of granuloma formation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Tnfaip3

tumor necrosis factor, alpha-induced protein 3

involved_in

(MGI:3763997|PMID:18006655)

PMID:18006655

MGI:3763997

NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405

negative regulation of hematopoietic stem cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cebpa

CCAAT/enhancer binding protein (C/EBP), alpha

acts_upstream_of_or_within

(MGI:3055255|PMID:15073037)

PMID:15073037

MGI:3055255

NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353

Mir221

microRNA 221

involved_in

(PMID:16330772)

PMID:16330772

NCBI chr X:19,012,533...19,012,627
Ensembl chr X:19,012,533...19,012,627

Mir222

microRNA 222

involved_in

(PMID:16330772)

PMID:16330772

NCBI chr X:19,013,132...19,013,210
Ensembl chr X:19,013,132...19,013,210

Snai2

snail family zinc finger 2

acts_upstream_of_or_within

(MGI:4436954|PMID:20032500)

PMID:20032500

MGI:4436954

NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249

negative regulation of hemopoiesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hspa9

heat shock protein 9

involved_in

(MGI:5784980|PMID:21123823)

PMID:21123823

MGI:5784980

NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410

Il17d

interleukin 17D

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr14:57,762,286...57,780,623
Ensembl chr14:57,762,234...57,780,623

negative regulation of humoral immune response mediated by circulating immunoglobulin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fc receptor, IgG, low affinity IIb

acts_upstream_of_or_within

(MGI:3608295|PMID:12385742)

PMID:12385742

MGI:3608295

NCBI chr 1:170,788,127...170,803,691
Ensembl chr 1:170,786,186...170,804,116

Foxj1

forkhead box J1

involved_in

(MGI:3589323|PMID:16002694)

PMID:16002694

MGI:3589323

NCBI chr11:116,221,530...116,226,331
Ensembl chr11:116,221,530...116,226,225

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

acts_upstream_of_or_within

(MGI:1095647|PMID:9254656)

PMID:9254656

MGI:1095647

NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677

negative regulation of immature T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gnrh1

gonadotropin releasing hormone 1

involved_in

PMID:11092955

GO_REF:0000096 MGI:4417868 RGD:9685051

NCBI chr14:67,982,630...67,986,885
Ensembl chr14:67,982,630...67,986,888

negative regulation of immature T cell proliferation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bmp4

bone morphogenetic protein 4

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126

Cdkn2a

cyclin dependent kinase inhibitor 2A

involved_in

(MGI:3615850|PMID:15964995)

HGNC-UCL

PMID:15964995

MGI:3615850

NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890

Clec4g

C-type lectin domain family 4, member g

acts_upstream_of_or_within

(MGI:5475030|PMID:23487419)

PMID:23487419

MGI:5475030

NCBI chr 8:3,757,066...3,770,695
Ensembl chr 8:3,757,064...3,770,651

Erbb2

erb-b2 receptor tyrosine kinase 2

acts_upstream_of_or_within

(MGI:3695084|PMID:16230479)

PMID:16230479

MGI:3695084

NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542

Ihh

Indian hedgehog

involved_in

(MGI:3836494|PMID:19109233)

PMID:19109233

MGI:3836494

NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831

Tmem131l

transmembrane 131 like

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 3:83,805,512...83,947,497
Ensembl chr 3:83,804,962...83,947,482

negative regulation of immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

C9orf72

C9orf72, member of C9orf72-SMCR8 complex

involved_in

(MGI:6284045|PMID:29950492)

PMID:29950492

MGI:6284045

NCBI chr 4:35,191,285...35,226,153
Ensembl chr 4:35,191,285...35,226,175

Col3a1

collagen, type III, alpha 1

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866

Ctla4

cytotoxic T-lymphocyte-associated protein 4

involved_in

PMID:15849541

GO_REF:0000096 MGI:4417868 RGD:2302005

NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991

Fc receptor, IgG, low affinity IIb

acts_upstream_of_or_within

(MGI:1340171|PMID:10395649), (MGI:2179576|PMID:11994421), (MGI:78617|PMID:8552190)

PMID:8552190 PMID:10395649 PMID:11994421

MGI:1340171 MGI:2179576 MGI:78617

NCBI chr 1:170,788,127...170,803,691
Ensembl chr 1:170,786,186...170,804,116

Fcrlb

Fc receptor-like B

acts_upstream_of_or_within
involved_in

(MGI:4837274|PMID:20869045)
(MGI:6201960|PMID:21873635)

PMID:20869045 PMID:21873635

MGI:4837274 MGI:6201960

NCBI chr 1:170,734,284...170,741,396
Ensembl chr 1:170,734,842...170,740,510

Foxp3

forkhead box P3

involved_in

GO_REF:0000096 MGI:4834177

NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484

inositol polyphosphate-5-phosphatase D

acts_upstream_of_or_within

(MGI:1354084|PMID:10704460)

PMID:10704460

MGI:1354084

NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229

Nlrp6

NLR family, pyrin domain containing 6

acts_upstream_of_or_within

(MGI:5432950|PMID:22763455)

PMID:22763455

MGI:5432950

NCBI chr 7:140,500,815...140,509,105
Ensembl chr 7:140,500,815...140,509,105

Olfm4

olfactomedin 4

acts_upstream_of_or_within

(MGI:4457946|PMID:20534456)

PMID:20534456

MGI:4457946

NCBI chr14:80,237,742...80,260,581
Ensembl chr14:80,221,521...80,260,579

Pdcd1

programmed cell death 1

involved_in

(MGI:1929567|PMID:11209085), (MGI:2386198|PMID:10485649)

PMID:10485649 PMID:11209085

MGI:1929567 MGI:2386198

NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278

Smcr8

Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)

involved_in

(MGI:6284045|PMID:29950492)

PMID:29950492

MGI:6284045

NCBI chr11:60,668,351...60,679,113
Ensembl chr11:60,668,350...60,679,113

Tgfb1

transforming growth factor, beta 1

involved_in

PMID:12130550

GO_REF:0000096 MGI:4417868 RGD:730199

NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502

Tgfb2

transforming growth factor, beta 2

involved_in

PMID:12130550

GO_REF:0000096 MGI:4417868 RGD:730199

NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186

Wdr41

WD repeat domain 41

involved_in

(MGI:6284045|PMID:29950492)

PMID:29950492

MGI:6284045

NCBI chr13:95,112,226...95,161,800
Ensembl chr13:95,112,852...95,159,822

negative regulation of immune response to tumor cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Havcr2

hepatitis A virus cellular receptor 2

involved_in

(MGI:5437532|PMID:22842346)

PMID:22842346

MGI:5437532

NCBI chr11:46,345,758...46,372,082
Ensembl chr11:46,345,762...46,372,082

negative regulation of immune system process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Igf1

insulin-like growth factor 1

involved_in

PMID:8575560

GO_REF:0000096 MGI:4417868 RGD:12904930

NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904

Sox9

SRY (sex determining region Y)-box 9

involved_in

(MGI:4947506|PMID:20056916)

PMID:20056916

MGI:4947506

NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586

negative regulation of immunoglobulin production

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd22

CD22 antigen

involved_in

(MGI:4453395|PMID:20200274)

PMID:20200274

MGI:4453395

NCBI chr 7:30,564,829...30,579,767
Ensembl chr 7:30,564,827...30,579,767

Fc receptor, IgG, low affinity IIb

acts_upstream_of_or_within

(MGI:3608295|PMID:12385742)

PMID:12385742

MGI:3608295

NCBI chr 1:170,788,127...170,803,691
Ensembl chr 1:170,786,186...170,804,116

Il13ra2

interleukin 13 receptor, alpha 2

acts_upstream_of_or_within

(MGI:3589858|PMID:15944273)

PMID:15944273

MGI:3589858

NCBI chr X:146,166,474...146,214,982
Ensembl chr X:146,166,472...146,212,188

Il33

interleukin 33

involved_in

(MGI:3775141|PMID:18268038)

PMID:18268038

MGI:3775141

NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118

leukocyte immunoglobulin-like receptor, subfamily B, member 4A

involved_in

(MGI:6810286|PMID:24935931)

PMID:24935931

MGI:6810286

NCBI chr10:51,366,994...51,372,709
Ensembl chr10:51,356,708...51,372,709
Ensembl chr10:51,356,708...51,372,709

Prkdc

protein kinase, DNA activated, catalytic polypeptide

involved_in

PMID:22981234

GO_REF:0000096 MGI:4417868 RGD:8696027

NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099

Siglecg

sialic acid binding Ig-like lectin G

involved_in

(MGI:4453395|PMID:20200274)

PMID:20200274

MGI:4453395

NCBI chr 7:43,057,617...43,067,773
Ensembl chr 7:43,057,628...43,067,782

Tmbim6

transmembrane BAX inhibitor motif containing 6

involved_in