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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet degranulation
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Accession:GO:0002576 term browser browse the term
Definition:The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
Synonyms:exact_synonym: platelet exocytosis


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platelet degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLK BLK proto-oncogene, Src family tyrosine kinase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:14,688,489...14,745,946
Ensembl chr14:14,688,123...14,746,414
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:75,793,273...75,903,710
Ensembl chr 4:75,786,099...75,868,591
JBrowse link
G PLEK pleckstrin ISO (PMID:7559487) BHF-UCL PMID:7559487 NCBI chr 3:73,877,741...73,910,163
Ensembl chr 3:73,877,743...74,005,519
JBrowse link
G STXBP1 syntaxin binding protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:268,116,124...268,205,805
Ensembl chr 1:268,116,118...268,213,921
JBrowse link
protein secretion by platelet term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMTN dematin actin binding protein IEA Ensembl GO_REF:0000107 NCBI chr14:6,315,643...6,346,722
Ensembl chr14:6,321,870...6,346,870
JBrowse link
G PLEK pleckstrin IEA Ensembl GO_REF:0000107 NCBI chr 3:73,877,741...73,910,163
Ensembl chr 3:73,877,743...74,005,519
JBrowse link
serotonin secretion by platelet term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER1G Fc fragment of IgE receptor Ig ISO (MGI:MGI:87668|PMID:9171347) UniProtKB PMID:9171347 MGI:MGI:87668 NCBI chr 4:89,242,467...89,246,344
Ensembl chr 4:89,242,459...89,247,065
JBrowse link
G P2RX1 purinergic receptor P2X 1 IEA Ensembl GO_REF:0000107 NCBI chr12:49,956,329...49,974,789
Ensembl chr12:49,956,323...49,974,671
JBrowse link
G SYK spleen associated tyrosine kinase ISS
IEA
UniProt
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr14:2,103,706...2,160,886
Ensembl chr14:2,056,712...2,161,172
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16524
    cellular process 15759
      cellular localization 2749
        establishment of localization in cell 2023
          platelet degranulation 8
            histamine secretion by platelet 0
            protein secretion by platelet 2
            serotonin secretion by platelet 3
Path 2
Term Annotations click to browse term
  biological_process 16524
    localization 5918
      establishment of localization 4437
        transport 4296
          export from cell 1023
            secretion by cell 973
              exocytosis 381
                regulated exocytosis 258
                  platelet degranulation 8
                    histamine secretion by platelet 0
                    protein secretion by platelet 2
                    serotonin secretion by platelet 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.