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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet degranulation
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Accession:GO:0002576 term browser browse the term
Definition:The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
Synonyms:exact_synonym: platelet exocytosis


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platelet degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLK BLK proto-oncogene, Src family tyrosine kinase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr25:26,336,253...26,357,494
Ensembl chr25:26,336,892...26,358,015
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507
JBrowse link
G PLEK pleckstrin ISO (PMID:7559487) BHF-UCL PMID:7559487 NCBI chr10:67,395,972...67,421,247
Ensembl chr10:67,395,972...67,421,247
JBrowse link
G STXBP1 syntaxin binding protein 1 ISO (PMID:12773094) UniProtKB PMID:12773094 NCBI chr 9:55,690,939...55,768,008
Ensembl chr 9:55,678,264...55,727,680
JBrowse link
protein secretion by platelet term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMTN dematin actin binding protein IEA Ensembl GO_REF:0000107 NCBI chr25:35,163,867...35,188,761
Ensembl chr25:35,165,876...35,176,754
JBrowse link
G PLEK pleckstrin IEA Ensembl GO_REF:0000107 NCBI chr10:67,395,972...67,421,247
Ensembl chr10:67,395,972...67,421,247
JBrowse link
serotonin secretion by platelet term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER1G Fc fragment of IgE receptor Ig IEA Ensembl GO_REF:0000107 NCBI chr38:21,267,841...21,271,036
Ensembl chr38:21,268,001...21,270,940
JBrowse link
G P2RX1 purinergic receptor P2X 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:47,674,175...47,694,358
Ensembl chr 9:47,675,300...47,688,858
JBrowse link
G SYK spleen associated tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16162
    cellular process 15439
      cellular localization 2784
        establishment of localization in cell 2055
          platelet degranulation 8
            histamine secretion by platelet 0
            protein secretion by platelet 2
            serotonin secretion by platelet 3
Path 2
Term Annotations click to browse term
  biological_process 16162
    localization 5964
      establishment of localization 4479
        transport 4337
          export from cell 1005
            secretion by cell 956
              exocytosis 381
                regulated exocytosis 261
                  platelet degranulation 8
                    histamine secretion by platelet 0
                    protein secretion by platelet 2
                    serotonin secretion by platelet 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.