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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet degranulation
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Accession:GO:0002576 term browser browse the term
Definition:The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
Synonyms:exact_synonym: platelet exocytosis


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platelet degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lyn LYN proto-oncogene, Src family tyrosine kinase ISO (MGI:MGI:5298337|PMID:20189992) UniProtKB PMID:20189992 MGI:MGI:5298337 NCBI chrNW_004955454:15,025,967...15,111,142 JBrowse link
G Plek pleckstrin ISO (PMID:7559487) BHF-UCL PMID:7559487 NCBI chrNW_004955424:16,494,052...16,524,790 JBrowse link
G Stxbp1 syntaxin binding protein 1 ISO (PMID:12773094) UniProtKB PMID:12773094 NCBI chrNW_004955419:963,829...1,000,759 JBrowse link
protein secretion by platelet term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmtn dematin actin binding protein ISO (MGI:MGI:5465511|PMID:23060452) UniProtKB PMID:23060452 MGI:MGI:5465511 NCBI chrNW_004955403:45,566,180...45,579,062 JBrowse link
G Plek pleckstrin ISO (MGI:MGI:3844782|PMID:19190246) BHF-UCL PMID:19190246 MGI:MGI:3844782 NCBI chrNW_004955424:16,494,052...16,524,790 JBrowse link
serotonin secretion by platelet term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig ISO (MGI:MGI:87668|PMID:9171347) UniProtKB PMID:9171347 MGI:MGI:87668 NCBI chrNW_004955468:12,971,931...12,975,206 JBrowse link
G P2rx1 purinergic receptor P2X 1 ISO (MGI:MGI:2671726|PMID:12913094) MGI PMID:12913094 MGI:MGI:2671726 NCBI chrNW_004955467:12,955,663...12,971,547 JBrowse link
G Syk spleen associated tyrosine kinase ISO (MGI:MGI:87668|PMID:9171347) UniProtKB PMID:9171347 MGI:MGI:87668 NCBI chrNW_004955515:1,328,793...1,400,206 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11857
    cellular process 11058
      cellular localization 2289
        establishment of localization in cell 1620
          platelet degranulation 7
            histamine secretion by platelet 0
            protein secretion by platelet 2
            serotonin secretion by platelet 3
Path 2
Term Annotations click to browse term
  biological_process 11857
    localization 4748
      establishment of localization 3414
        transport 3270
          export from cell 899
            secretion by cell 854
              exocytosis 302
                regulated exocytosis 229
                  platelet degranulation 7
                    histamine secretion by platelet 0
                    protein secretion by platelet 2
                    serotonin secretion by platelet 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.