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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet degranulation
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Accession:GO:0002576 term browser browse the term
Definition:The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
Synonyms:exact_synonym: platelet exocytosis


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platelet degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:5298337|PMID:20189992) UniProt PMID:20189992 MGI:5298337 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142
JBrowse link
G Plek pleckstrin involved_in ISO (PMID:7559487) BHF-UCL PMID:7559487 NCBI chrNW_004955424:16,494,052...16,524,790
Ensembl chrNW_004955424:16,493,960...16,524,998
JBrowse link
G Stxbp1 syntaxin binding protein 1 involved_in ISO (PMID:12773094) UniProt PMID:12773094 NCBI chrNW_004955419:963,829...1,000,759
Ensembl chrNW_004955419:963,829...1,000,759
JBrowse link
G Tph1 tryptophan hydroxylase 1 involved_in ISO (MGI:2683993|PMID:14697203) UniProt PMID:14697203 MGI:2683993 NCBI chrNW_004955414:32,803,417...32,828,682
Ensembl chrNW_004955414:32,800,477...32,828,501
JBrowse link
protein secretion by platelet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plek pleckstrin involved_in ISO (MGI:3844782|PMID:19190246) BHF-UCL PMID:19190246 MGI:3844782 NCBI chrNW_004955424:16,494,052...16,524,790
Ensembl chrNW_004955424:16,493,960...16,524,998
JBrowse link
serotonin secretion by platelet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig involved_in ISO (MGI:87668|PMID:9171347) UniProt PMID:9171347 MGI:87668 NCBI chrNW_004955468:12,971,931...12,975,206
Ensembl chrNW_004955468:12,971,931...12,975,206
JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO (PMID:12913094) MGI PMID:12913094 NCBI chrNW_004955467:12,955,663...12,971,547
Ensembl chrNW_004955467:12,955,672...12,971,547
JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO (MGI:87668|PMID:9171347) UniProt PMID:9171347 MGI:87668 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12321
    cellular process 11505
      cellular localization 2947
        establishment of localization in cell 1677
          platelet degranulation 7
            histamine secretion by platelet 0
            protein secretion by platelet 1
            serotonin secretion by platelet 3
Path 2
Term Annotations click to browse term
  biological_process 12321
    localization 4252
      establishment of localization 3589
        transport 3317
          export from cell 919
            secretion by cell 858
              exocytosis 312
                regulated exocytosis 233
                  platelet degranulation 7
                    histamine secretion by platelet 0
                    protein secretion by platelet 1
                    serotonin secretion by platelet 3
paths to the root