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ONTOLOGY REPORT - ANNOTATIONS

Term:production of molecular mediator involved in inflammatory response
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Accession:GO:0002532 term browser browse the term
Definition:The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:broad_synonym: production of molecular mediator involved in acute inflammatory response
 related_synonym: production of cellular mediator of acute inflammation


show annotations for term's descendants           Sort by:
production of molecular mediator involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO (PMID:20610799) RGD PMID:20610799 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Chia chitinase, acidic involved_in ISO
ISS		 (PMID:18824549)
GO_REF:0000024		 RGD
UniProt		 PMID:18824549 GO_REF:0000024 NCBI chr 2:193,614,374...193,656,532
Ensembl chr 2:193,614,114...193,656,533 		JBrowse link
G Il4r interleukin 4 receptor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980 		JBrowse link
G Pbxip1 PBX homeobox interacting protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3665440|MGI:6363079 (PMID:30659184)		 Ensembl
RGD		 PMID:30659184 GO_REF:0000107 NCBI chr 2:174,856,339...174,868,922
Ensembl chr 2:174,856,397...174,868,919 		JBrowse link
G Pla2g10 phospholipase A2, group X involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4412409 (PMID:26828067)		 Ensembl
RGD		 PMID:26828067 GO_REF:0000107 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000 		JBrowse link
G Pla2g3 phospholipase A2, group III acts_upstream_of_or_within ISO MGI:4461174 (PMID:28947740) RGD PMID:28947740 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913 		JBrowse link
arachidonate metabolite production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fads2 fatty acid desaturase 2 IMP RGD PMID:24284026 RGD:401901245 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789 		JBrowse link
histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora3 adenosine A3 receptor acts_upstream_of_or_within ISO MGI:2155986 (PMID:12817016) RGD PMID:12817016 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357 		JBrowse link
G Btk Bruton tyrosine kinase IMP RGD PMID:12220673 RGD:1600535 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IMP RGD PMID:16177098 RGD:1578516 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Rab44 RAB44, member RAS oncogene family acts_upstream_of_or_within ISO MGI:6695900 (PMID:32238914) RGD PMID:32238914 NCBI chr20:7,164,576...7,198,473
Ensembl chr20:7,164,720...7,198,468 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:10618388)		 Ensembl
RGD		 PMID:10618388 GO_REF:0000107 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Snap23 synaptosome associated protein 23 involved_in ISO
IEA		 (PMID:18253931)
GO_REF:0000107		 RGD
Ensembl		 PMID:18253931 GO_REF:0000107 NCBI chr 3:107,514,088...107,546,177
Ensembl chr 3:107,514,131...107,544,320 		JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta IMP RGD PMID:12499633 RGD:1625716 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668 		JBrowse link
histamine secretion mediated by IgE immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab44 RAB44, member RAS oncogene family acts_upstream_of_or_within ISO MGI:6695900 (PMID:32238914) RGD PMID:32238914 NCBI chr20:7,164,576...7,198,473
Ensembl chr20:7,164,720...7,198,468 		JBrowse link
leukotriene production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1933120 (PMID:9091580)		 Ensembl
RGD		 PMID:9091580 GO_REF:0000107 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein acts_upstream_of_or_within ISO MGI:2156546 (PMID:10779800), (PMID:9091580) RGD PMID:9091580 PMID:10779800 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986 		JBrowse link
negative regulation of cytokine production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18723473)		 UniProt
RGD		 PMID:18723473 GO_REF:0000024 NCBI chr  X:151,428,334...151,450,115
Ensembl chr  X:151,428,578...151,450,115 		JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18723473)		 UniProt
RGD		 PMID:18723473 GO_REF:0000024 NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642 		JBrowse link
G Adcy7 adenylate cyclase 7 involved_in ISO (PMID:20505140) RGD PMID:20505140 NCBI chr19:18,740,875...18,798,924
Ensembl chr19:18,740,875...18,776,311 		JBrowse link
G Apod apolipoprotein D involved_in ISO
ISS		 (PMID:18842892)
GO_REF:0000024		 RGD
UniProt		 PMID:18842892 GO_REF:0000024 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (PMID:25328665) RGD PMID:25328665 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
G Chid1 chitinase domain containing 1 involved_in ISO
IEA		 (PMID:20724479)
GO_REF:0000107		 RGD
Ensembl		 PMID:20724479 GO_REF:0000107 NCBI chr 1:196,594,357...196,629,700
Ensembl chr 1:196,587,509...196,629,606 		JBrowse link
G Cuedc2 CUE domain containing 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24882011)
MGI:5635142 (PMID:24882011)
GO_REF:0000107		 RGD
Ensembl		 PMID:24882011 GO_REF:0000107 NCBI chr 1:245,192,057...245,200,594
Ensembl chr 1:245,192,063...245,200,339 		JBrowse link
G Ephb2 Eph receptor B2 IDA RGD PMID:33722292 RGD:127285641 NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059 		JBrowse link
G Extl3 exostosin-like glycosyltransferase 3 involved_in ISO (PMID:28811323) RGD PMID:28811323 NCBI chr15:39,294,033...39,384,086
Ensembl chr15:39,293,605...39,338,898 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit IMP RGD PMID:27690696 RGD:126781724 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA
ISO		 GO_REF:0000107
(PMID:20421939)		 Ensembl
RGD		 PMID:20421939 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:23395675)		 Ensembl
RGD		 PMID:23395675 GO_REF:0000107 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:19380766) RGD PMID:19380766 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Macir macrophage immunometabolism regulator involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:26316022)		 GO_Central
RGD		 PMID:26316022 GO_REF:0000033 NCBI chr 9:98,420,760...98,440,818
Ensembl chr 9:98,420,376...98,441,733 		JBrowse link
G Mefv MEFV innate immunity regulator, pyrin involved_in ISS
ISO		 GO_REF:0000024
(PMID:26347139)		 UniProt
RGD		 PMID:26347139 GO_REF:0000024 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973 		JBrowse link
G Mir136 microRNA 136 involved_in ISO (PMID:30233690) RGD PMID:30233690 NCBI chr 6:128,549,096...128,549,177
Ensembl chr 6:128,549,096...128,549,177 		JBrowse link
G Mir140 microRNA 140 acts_upstream_of ISO (PMID:30321456) RGD PMID:30321456 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir146a microRNA 146a involved_in ISO (PMID:29896267) RGD PMID:29896267 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mir26a microRNA 26a involved_in ISO (PMID:27252421) RGD PMID:27252421 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378 		JBrowse link
G Mir93 microRNA 93 involved_in ISO (PMID:26986724) RGD PMID:26986724 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221 		JBrowse link
G Mir98 microRNA 98 involved_in ISO (PMID:31886314) RGD PMID:31886314 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO (PMID:24560620) RGD PMID:24560620 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398 		JBrowse link
G Pdcd4 programmed cell death 4 involved_in ISO (PMID:17114484), (PMID:19946272) RGD PMID:17114484 PMID:19946272 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275 		JBrowse link
G Pla2g10 phospholipase A2, group X involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4412409 (PMID:26828067)		 Ensembl
RGD		 PMID:26828067 GO_REF:0000107 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:24531343) RGD PMID:24531343 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Sirpa signal-regulatory protein alpha involved_in ISO RNAcentral:URS00002075FA_10090 (PMID:17954568), (PMID:23562609) RGD PMID:17954568 PMID:23562609 NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098 		JBrowse link
G Spink7 serine peptidase inhibitor, Kazal type 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:6764496 (PMID:33722746)		 Ensembl
RGD		 PMID:33722746 GO_REF:0000107 NCBI chr18:56,045,996...56,049,761
Ensembl chr18:56,045,930...56,049,744 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29887864) RGD PMID:29887864 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO		 GO_REF:0000024
(PMID:21616078)		 UniProt
RGD		 PMID:21616078 GO_REF:0000024 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
negative regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dusp10 dual specificity phosphatase 10 acts_upstream_of_or_within ISO MGI:3052343 (PMID:19696743) RGD PMID:19696743 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Grn granulin precursor involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:12526812)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:12526812 GO_REF:0000024 GO_REF:0000107 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:11443198) RGD PMID:11443198 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Rps19 ribosomal protein S19 involved_in ISO (PMID:15750715) RGD PMID:15750715 NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
Ensembl chr 7:80,480,951...80,486,508 		JBrowse link
G Slamf8 SLAM family member 8 acts_upstream_of_or_within ISO MGI:5442794 (PMID:25799045) RGD PMID:25799045 NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211 		JBrowse link
nitric oxide production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc7a2 solute carrier family 7 member 2 acts_upstream_of_or_within ISO MGI:2150359 (PMID:11278602), (PMID:17003120) RGD PMID:11278602 PMID:17003120 NCBI chr16:51,417,478...51,470,784
Ensembl chr16:51,417,493...51,470,784 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857718 (PMID:10623794)		 Ensembl
RGD		 PMID:10623794 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
positive regulation of cytokine production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd42 ankyrin repeat domain 42 acts_upstream_of_or_within ISO (PMID:20547855) RGD PMID:20547855 NCBI chr 1:146,648,080...146,691,086
Ensembl chr 1:146,648,080...146,691,108 		JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:25328665) RGD PMID:25328665 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
G Card9 caspase recruitment domain family, member 9 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25267792)		 UniProt
RGD		 PMID:25267792 GO_REF:0000024 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Cd6 Cd6 molecule involved_in ISO (PMID:17601777) RGD PMID:17601777 NCBI chr 1:207,442,873...207,481,703
Ensembl chr 1:207,442,877...207,481,634 		JBrowse link
G Cd74 CD74 molecule involved_in ISO (PMID:23736979) RGD PMID:23736979 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:22267217) RGD PMID:22267217 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:22461501) RGD PMID:22461501 NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061 		JBrowse link
G Gpsm3 G-protein signaling modulator 3 acts_upstream_of_or_within ISO MGI:4075252 (PMID:23280397) RGD PMID:23280397 NCBI chr20:4,157,123...4,158,984
Ensembl chr20:4,157,123...4,159,035 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISO
IEA
ISS		 (PMID:32697943)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:32697943 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Il17a interleukin 17A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:107399|MGI:2159336 (PMID:16785495), (PMID:17982105)
(PMID:29734196)		 Ensembl
RGD		 PMID:16785495 PMID:17982105 PMID:29734196 GO_REF:0000107 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il17b interleukin 17B acts_upstream_of_or_within ISO (PMID:17982105) RGD PMID:17982105 NCBI chr18:55,141,194...55,145,565
Ensembl chr18:55,141,194...55,145,565 		JBrowse link
G Il17c interleukin 17C acts_upstream_of_or_within ISO (PMID:17982105) RGD PMID:17982105 NCBI chr19:50,484,890...50,486,169
Ensembl chr19:50,484,890...50,486,169 		JBrowse link
G Il17d interleukin 17D involved_in ISO (PMID:12097364) RGD PMID:12097364 NCBI chr15:31,671,337...31,688,833 JBrowse link
G Il17f interleukin 17F involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:107399 (PMID:16785495), (PMID:17982105)		 Ensembl
RGD		 PMID:16785495 PMID:17982105 GO_REF:0000107 NCBI chr 9:23,190,094...23,201,482
Ensembl chr 9:23,190,100...23,201,482 		JBrowse link
G Il17ra interleukin 17 receptor A involved_in
acts_upstream_of_or_within		 ISO (PMID:33723527)
MGI:107364|MGI:2676631 (PMID:16785495)		 RGD PMID:16785495 PMID:33723527 NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174 		JBrowse link
G Il17rc interleukin 17 receptor C acts_upstream_of_or_within ISO MGI:107364 (PMID:16785495) RGD PMID:16785495 NCBI chr 4:146,618,321...146,631,444
Ensembl chr 4:146,619,004...146,631,442 		JBrowse link
G Il6 interleukin 6 involved_in ISO RNAcentral:URS00004E0808_9606 (PMID:31886314) RGD PMID:31886314 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Kpna6 karyopherin subunit alpha 6 acts_upstream_of_or_within ISO MGI:3856636 (PMID:28189564) RGD PMID:28189564 NCBI chr 5:141,988,111...142,021,483
Ensembl chr 5:141,991,568...142,021,120 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 involved_in ISO
IEA		 (PMID:8654373)
(PMID:27830702)
GO_REF:0000107		 RGD
Ensembl		 PMID:8654373 PMID:27830702 GO_REF:0000107 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mir324 microRNA 324 acts_upstream_of_or_within ISO (PMID:24882011) RGD PMID:24882011 NCBI chr10:54,734,680...54,734,762
Ensembl chr10:54,734,678...54,734,766 		JBrowse link
G Mir675 microRNA 675 acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 1:197,732,275...197,732,358
Ensembl chr 1:197,732,275...197,732,358 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO (PMID:20219467)
(PMID:20037584)		 RGD PMID:20037584 PMID:20219467 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:24671169) RGD PMID:24671169 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Pla2g3 phospholipase A2, group III acts_upstream_of_or_within ISO MGI:4461174 (PMID:28947740) RGD PMID:28947740 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO
IEA		 RNAcentral:URS00004E0808_9606|UniProtKB:P05231 (PMID:31886314)
GO_REF:0000107		 RGD
Ensembl		 PMID:31886314 GO_REF:0000107 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 involved_in ISO (PMID:26311901) RGD PMID:26311901 NCBI chr 1:65,666,742...65,682,402
Ensembl chr 1:65,671,902...65,679,626 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 involved_in ISO (PMID:20037584) RGD PMID:20037584 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tlr3 toll-like receptor 3 involved_in ISO (PMID:27830702) RGD PMID:27830702 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q9Y2C9 (PMID:20037584)
(PMID:30321456)		 Ensembl
RGD		 PMID:20037584 PMID:30321456 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO UniProtKB:O00206 (PMID:20037584) RGD PMID:20037584 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of
acts_upstream_of_or_within		 ISO (PMID:31824476)
RNAcentral:URS00004DA9DB_9606 (PMID:23608026)		 RGD PMID:23608026 PMID:31824476 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide A involved_in IDA PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Pla2g3 phospholipase A2, group III involved_in ISO (PMID:23624557) RGD PMID:23624557 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913 		JBrowse link
G Snx4 sorting nexin 4 involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr11:67,460,872...67,518,143
Ensembl chr11:67,460,870...67,518,174 		JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr12:16,728,486...16,764,261
Ensembl chr12:16,728,524...16,764,097 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18253931)		 Ensembl
RGD		 PMID:18253931 GO_REF:0000107 NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897 		JBrowse link
positive regulation of leukotriene production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpine1 serpin family E member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19916862)		 Ensembl
RGD		 PMID:19916862 GO_REF:0000107 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
positive regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lbp lipopolysaccharide binding protein involved_in IEA
ISO		 GO_REF:0000107
(PMID:9338787)		 Ensembl
RGD		 PMID:9338787 GO_REF:0000107 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Rps19 ribosomal protein S19 involved_in ISO (PMID:15750715) RGD PMID:15750715 NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
Ensembl chr 7:80,480,951...80,486,508 		JBrowse link
prostaglandin production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camp cathelicidin antimicrobial peptide IDA RGD PMID:26527065 RGD:435861584 NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543 		JBrowse link
G Ephx2 epoxide hydrolase 2 IMP RGD PMID:16962614 RGD:5688387 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615 		JBrowse link
regulation of cytokine production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:28965882)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:28965882 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Bap1 BRCA1 associated deubiquitinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5439653 (PMID:26119930)		 Ensembl
RGD		 PMID:26119930 GO_REF:0000107 NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535 		JBrowse link
G Lep leptin involved_in ISO
ISS		 (PMID:19688109)
GO_REF:0000024		 RGD
UniProt		 PMID:19688109 GO_REF:0000024 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 involved_in ISO
IEA		 (PMID:15251176)
GO_REF:0000107		 RGD
Ensembl		 PMID:15251176 GO_REF:0000107 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:31490757 RGD:26884457 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir98 microRNA 98 involved_in ISO (PMID:29702181) RGD PMID:29702181 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
G Nos2 nitric oxide synthase 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19688109)		 UniProt
Ensembl
RGD		 PMID:19688109 GO_REF:0000024 GO_REF:0000107 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Per1 period circadian regulator 1 involved_in IMP PMID:24447840 UniProt PMID:24447840 RGD:8655527 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431 		JBrowse link
G Pld3 phospholipase D family, member 3 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:22102906)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:22102906 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:82,821,863...82,844,280
Ensembl chr 1:82,821,875...82,844,072 		JBrowse link
G Pld4 phospholipase D family, member 4 involved_in ISO (PMID:22102906) RGD PMID:22102906 NCBI chr 6:131,818,860...131,827,457
Ensembl chr 6:131,818,860...131,826,376 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29663649) RGD PMID:29663649 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snx6 sorting nexin 6 NOT|involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr 6:72,230,950...72,274,157
Ensembl chr 6:72,229,870...72,315,911 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 NOT|involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809 		JBrowse link
G Vamp3 vesicle-associated membrane protein 3 NOT|involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr 5:161,498,109...161,508,704
Ensembl chr 5:161,498,109...161,508,751 		JBrowse link
regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ncf1 neutrophil cytosolic factor 1 IMP RGD PMID:21275845 RGD:41404729 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipa lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:6364606 (PMID:25807535), (PMID:33357458)		 Ensembl
RGD		 PMID:25807535 PMID:33357458 GO_REF:0000107 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Prdx2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2668456 (PMID:17325201)		 Ensembl
RGD		 PMID:17325201 GO_REF:0000107 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
serotonin secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule acts_upstream_of_or_within ISO (PMID:12874256) RGD PMID:12874256 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:10618388)		 Ensembl
RGD		 PMID:10618388 GO_REF:0000107 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
serotonin secretion by platelet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc epsilon receptor Ig involved_in ISO (PMID:9171347) RGD PMID:9171347 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO MGI:2181608 (PMID:12913094) RGD PMID:12913094 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:9171347)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:9171347 GO_REF:0000024 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    multicellular organismal process 8906
      production of molecular mediator involved in inflammatory response 107
        arachidonate metabolite production involved in inflammatory response + 6
        cytokine production involved in inflammatory response + 70
        histamine production involved in inflammatory response + 15
        lysosomal enzyme production involved in inflammatory response + 0
        nitric oxide production involved in inflammatory response 2
        platelet activating factor production involved in inflammatory response 0
        respiratory burst involved in inflammatory response + 9
        serotonin production involved in inflammatory response + 5
Path 2
Term Annotations click to browse term
  biological_process 20076
    response to stimulus 10795
      response to stress 4260
        defense response 1917
          inflammatory response 878
            production of molecular mediator involved in inflammatory response 107
              arachidonate metabolite production involved in inflammatory response + 6
              cytokine production involved in inflammatory response + 70
              histamine production involved in inflammatory response + 15
              lysosomal enzyme production involved in inflammatory response + 0
              nitric oxide production involved in inflammatory response 2
              platelet activating factor production involved in inflammatory response 0
              respiratory burst involved in inflammatory response + 9
              serotonin production involved in inflammatory response + 5
paths to the root