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ONTOLOGY REPORT - ANNOTATIONS

Term:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
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Accession:GO:0002479 term browser browse the term
Definition:The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules.
Synonyms:exact_synonym: TAP-dependent exogenous peptide antigen processing and presentation via MHC class I
 broad_synonym: cross presentation


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antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TAPBP TAP binding protein acts_upstream_of_or_within
involved_in		 ISO (PMID:9716645) MGI
UniProt		 PMID:9716645 NCBI chr 7:29,663,491...29,673,453
Ensembl chr 7:29,663,495...29,673,634 		JBrowse link
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  biological_process 17813
    immune system process 2474
      antigen processing and presentation 110
        antigen processing and presentation of peptide antigen 59
          antigen processing and presentation of peptide antigen via MHC class I 37
            antigen processing and presentation of exogenous peptide antigen via MHC class I 7
              antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 1
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