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ONTOLOGY REPORT - ANNOTATIONS


Term:antigen processing and presentation of peptide antigen via MHC class I
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Accession:GO:0002474 term browser browse the term
Definition:The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
Synonyms:exact_synonym: peptide antigen processing and presentation via MHC class I



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antigen processing and presentation of peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB9 ATP binding cassette subfamily B member 9 NOT|involved_in IDA (PMID:17977821) UniProt PMID:17977821 NCBI chr12:122,918,610...122,975,114
Ensembl chr12:122,920,951...122,981,649
JBrowse link
G ACE angiotensin I converting enzyme involved_in TAS (PMID:23257181) BHF-UCL PMID:23257181 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G B2M beta-2-microglobulin involved_in IEA UniProt GO_REF:0000043 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851
JBrowse link
G ERAP1 endoplasmic reticulum aminopeptidase 1 involved_in TAS Reactome Reactome:R-HSA-983169 NCBI chr 5:96,760,813...96,935,854
Ensembl chr 5:96,760,810...96,808,100
JBrowse link
G ERAP2 endoplasmic reticulum aminopeptidase 2 involved_in TAS Reactome Reactome:R-HSA-983169 NCBI chr 5:96,875,939...96,919,716
Ensembl chr 5:96,875,986...96,919,703
JBrowse link
G HFE homeostatic iron regulator NOT|involved_in IKR (PMID:8696333) BHF-UCL PMID:8696333 NCBI chr 6:26,087,429...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
G HLA-A major histocompatibility complex, class I, A involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572
JBrowse link
G HLA-B major histocompatibility complex, class I, B involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067
JBrowse link
G HLA-C major histocompatibility complex, class I, C involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:31,268,749...31,272,092
Ensembl chr 6:31,268,749...31,272,130
JBrowse link
G HLA-E major histocompatibility complex, class I, E involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194
JBrowse link
G HLA-F major histocompatibility complex, class I, F involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528
JBrowse link
G HLA-G major histocompatibility complex, class I, G involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125
JBrowse link
G HLA-H major histocompatibility complex, class I, H (pseudogene) involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:29,887,573...29,891,079
Ensembl chr 6:29,887,752...29,890,482
JBrowse link
G HLA-L major histocompatibility complex, class I, L (pseudogene) involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:30,259,562...30,266,951
Ensembl chr 6:30,259,548...30,293,015
Ensembl chr 6:30,259,548...30,293,015
JBrowse link
G MR1 major histocompatibility complex, class I-related involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:181,033,387...181,061,938
Ensembl chr 1:181,033,374...181,061,938
JBrowse link
G SAR1B secretion associated Ras related GTPase 1B involved_in TAS Reactome Reactome:R-HSA-983169 NCBI chr 5:134,601,149...134,632,828
Ensembl chr 5:134,601,149...134,649,271
JBrowse link
antigen processing and presentation of endogenous peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AL669918.1 novel protein, TAP2-HLA-DOB readthrough involved_in IEA InterPro GO_REF:0000002 Ensembl chr 6:32,813,767...32,838,822 JBrowse link
G B2M beta-2-microglobulin involved_in IGI (PMID:24643698) BHF-UCL PMID:24643698 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851
JBrowse link
G ERAP1 endoplasmic reticulum aminopeptidase 1 involved_in NAS
TAS
(PMID:12748171)
(PMID:15691326)
UniProt
HGNC-UCL
PMID:12748171 PMID:15691326 NCBI chr 5:96,760,813...96,935,854
Ensembl chr 5:96,760,810...96,808,100
JBrowse link
G ERAP2 endoplasmic reticulum aminopeptidase 2 involved_in TAS (PMID:15691326) HGNC-UCL PMID:15691326 NCBI chr 5:96,875,939...96,919,716
Ensembl chr 5:96,875,986...96,919,703
JBrowse link
G HLA-A major histocompatibility complex, class I, A involved_in IDA (PMID:1402688), (PMID:20364150), (PMID:24643698) UniProt PMID:1402688 PMID:20364150 PMID:24643698 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572
JBrowse link
G IDE insulin degrading enzyme involved_in IMP (PMID:20364150) UniProt PMID:20364150 NCBI chr10:92,451,684...92,574,093
Ensembl chr10:92,451,684...92,574,096
JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member involved_in IMP
IBA
IDA
(PMID:11133832) UniProt
GO_Central
PMID:11133832 GO_REF:0000033 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816
JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of_or_within
involved_in
ISO
IDA
IEA
IMP
PMID:1758495
(PMID:8496691)
(PMID:1538751)
MGI
UniProt
InterPro
PMID:1538751 PMID:1758495 PMID:8496691 GO_REF:0000002 RGD:1299069 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739
JBrowse link
G TAPBP TAP binding protein involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:33,299,694...33,314,078
Ensembl chr 6:33,299,694...33,314,284
JBrowse link
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-A major histocompatibility complex, class I, A involved_in IMP (PMID:8630735) UniProt PMID:8630735 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572
JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:50291|PMID:1538753) MGI
Ensembl
PMID:1538753 GO_REF:0000107 MGI:50291 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739
JBrowse link
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HFE homeostatic iron regulator involved_in IEA
IBA
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 6:26,087,429...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
G HLA-A major histocompatibility complex, class I, A involved_in IDA
IBA
IEA
(PMID:22031944) UniProt
GO_Central
TreeGrafter
PMID:22031944 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572
JBrowse link
G HLA-B major histocompatibility complex, class I, B involved_in IDA
IBA
IEA
(PMID:22031944) UniProt
GO_Central
TreeGrafter
PMID:22031944 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067
JBrowse link
G HLA-C major histocompatibility complex, class I, C involved_in IDA
IEA
IBA
(PMID:22031944) UniProt
TreeGrafter
GO_Central
PMID:22031944 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:31,268,749...31,272,092
Ensembl chr 6:31,268,749...31,272,130
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696
JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848
JBrowse link
G HLA-E major histocompatibility complex, class I, E involved_in IBA
IEA
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194
JBrowse link
G HLA-F major histocompatibility complex, class I, F involved_in IEA
IBA
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528
JBrowse link
G HLA-G major histocompatibility complex, class I, G involved_in IEA
IBA
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125
JBrowse link
G HLA-H major histocompatibility complex, class I, H (pseudogene) involved_in IBA
IEA
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 6:29,887,573...29,891,079
Ensembl chr 6:29,887,752...29,890,482
JBrowse link
G HLA-L major histocompatibility complex, class I, L (pseudogene) involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:30,259,562...30,266,951
Ensembl chr 6:30,259,548...30,293,015
Ensembl chr 6:30,259,548...30,293,015
JBrowse link
G MICA MHC class I polypeptide-related sequence A involved_in IBA
IEA
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 6:31,400,711...31,415,315
Ensembl chr 6:31,399,784...31,415,315
JBrowse link
G MICB MHC class I polypeptide-related sequence B involved_in IBA
IEA
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 6:31,494,918...31,511,124
Ensembl chr 6:31,494,881...31,511,124
JBrowse link
G MR1 major histocompatibility complex, class I-related involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:181,033,387...181,061,938
Ensembl chr 1:181,033,374...181,061,938
JBrowse link
G RAET1E retinoic acid early transcript 1E involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:149,883,179...149,898,113
Ensembl chr 6:149,883,179...149,898,113
JBrowse link
G RAET1G retinoic acid early transcript 1G involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:149,916,878...149,923,121
Ensembl chr 6:149,916,878...149,923,121
JBrowse link
G RAET1L retinoic acid early transcript 1L involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:150,018,334...150,025,532
Ensembl chr 6:150,018,334...150,025,532
JBrowse link
G ULBP1 UL16 binding protein 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:149,963,943...149,973,715
Ensembl chr 6:149,963,943...149,973,715
JBrowse link
G ULBP2 UL16 binding protein 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:149,942,014...149,949,235
Ensembl chr 6:149,942,014...149,949,235
JBrowse link
G ULBP3 UL16 binding protein 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:150,061,053...150,069,121
Ensembl chr 6:150,061,053...150,069,121
JBrowse link
antigen processing and presentation of exogenous peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC4A C-type lectin domain family 4 member A involved_in IDA (PMID:20530286) UniProt PMID:20530286 NCBI chr12:8,102,907...8,138,607
Ensembl chr12:8,123,617...8,138,607
JBrowse link
G FCER1G Fc epsilon receptor Ig acts_upstream_of_or_within
involved_in
ISO
IEA
IBA
(MGI:2664488|PMID:11911824) MGI
TreeGrafter
GO_Central
PMID:11911824 GO_REF:0000033 GO_REF:0000118 MGI:2664488 NCBI chr 1:161,215,295...161,219,245
Ensembl chr 1:161,215,234...161,220,699
JBrowse link
G FCGR1A Fc gamma receptor Ia acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2664488|PMID:11911824) MGI
Ensembl
PMID:11911824 GO_REF:0000107 MGI:2664488 NCBI chr 1:149,782,694...149,800,609
Ensembl chr 1:149,782,671...149,791,675
JBrowse link
G HLA-A major histocompatibility complex, class I, A involved_in IDA (PMID:12138174), (PMID:7504010) UniProt PMID:7504010 PMID:12138174 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572
JBrowse link
G IFI30 IFI30 lysosomal thiol reductase involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr19:18,173,813...18,178,117
Ensembl chr19:18,173,162...18,178,117
JBrowse link
G MFSD6 major facilitator superfamily domain containing 6 acts_upstream_of_or_within
involved_in
ISO
IBA
IEA
(MGI:3692789|PMID:17010536) MGI
GO_Central
TreeGrafter
PMID:17010536 GO_REF:0000033 GO_REF:0000118 MGI:3692789 NCBI chr 2:190,407,576...190,502,314
Ensembl chr 2:190,408,355...190,509,205
JBrowse link
G MPEG1 macrophage expressed 1 involved_in ISS (PMID:37347855) UniProt PMID:37347855 GO_REF:0000024 NCBI chr11:59,208,510...59,212,927
Ensembl chr11:59,208,510...59,212,927
JBrowse link
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-1236974 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460
JBrowse link
G TAPBP TAP binding protein acts_upstream_of_or_within
involved_in
ISO (MGI:1289739|PMID:9716645) MGI
UniProt
PMID:9716645 MGI:1289739 NCBI chr 6:33,299,694...33,314,078
Ensembl chr 6:33,299,694...33,314,284
JBrowse link
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LNPEP leucyl and cystinyl aminopeptidase involved_in TAS Reactome Reactome:R-HSA-1236977 NCBI chr 5:96,936,080...97,037,513
Ensembl chr 5:96,935,394...97,037,513
JBrowse link
negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HFE homeostatic iron regulator involved_in IGI (PMID:24643698) BHF-UCL PMID:24643698 NCBI chr 6:26,087,429...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
negative regulation of antigen processing and presentation of peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TAPBPL TAP binding protein like involved_in IDA (PMID:23401559) UniProt PMID:23401559 NCBI chr12:6,451,649...6,472,006
Ensembl chr12:6,451,690...6,466,517
JBrowse link
peptide antigen assembly with MHC class I protein complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2M beta-2-microglobulin involved_in IDA (PMID:36104323) UniProt PMID:36104323 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851
JBrowse link
G CALR calreticulin involved_in IEA
IDA
ISS
(PMID:35948544)
(PMID:11825569)
Ensembl
UniProt
BHF-UCL
PMID:11825569 PMID:35948544 GO_REF:0000107 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
JBrowse link
G HLA-A major histocompatibility complex, class I, A involved_in IDA (PMID:36104323) UniProt PMID:36104323 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572
JBrowse link
G NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:17,351,800...17,381,661
Ensembl chr11:17,351,800...17,377,341
JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 involved_in IDA (PMID:17603487) ComplexPortal PMID:17603487 NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,394...43,773,279
JBrowse link
G TAPBP TAP binding protein involved_in IDA
IBA
IEA
(PMID:10636848), (PMID:17603487) ComplexPortal
GO_Central
TreeGrafter
PMID:10636848 PMID:17603487 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:33,299,694...33,314,078
Ensembl chr 6:33,299,694...33,314,284
JBrowse link
G TAPBPL TAP binding protein like involved_in IDA
IBA
IEA
(PMID:26869717) UniProt
GO_Central
TreeGrafter
PMID:26869717 GO_REF:0000033 GO_REF:0000118 NCBI chr12:6,451,649...6,472,006
Ensembl chr12:6,451,690...6,466,517
JBrowse link
positive regulation of antigen processing and presentation of peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TAP2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:1758495 RGD:1299069 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739
JBrowse link

Term paths to the root