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ONTOLOGY REPORT - ANNOTATIONS


Term:mast cell mediated immunity
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Accession:GO:0002448 term browser browse the term
Definition:Any process involved in the carrying out of an immune response by a mast cell.



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mast cell mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ndst2 N-deacetylase and N-sulfotransferase 2 acts_upstream_of_or_within ISO MGI:1913285|MGI:1913286 (PMID:10466726), (PMID:10466727) RGD PMID:10466726 PMID:10466727 NCBI chr15:3,563,515...3,573,801
Ensembl chr15:3,563,358...3,573,801
JBrowse link
G Serpinb9 serpin family B member 9 involved_in ISO (PMID:15739160) RGD PMID:15739160 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within ISO MGI:3026870 (PMID:14691481) RGD PMID:14691481 NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996
JBrowse link
histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora3 adenosine A3 receptor acts_upstream_of_or_within ISO MGI:2155986 (PMID:12817016) RGD PMID:12817016 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357
JBrowse link
G Btk Bruton tyrosine kinase IMP RGD PMID:12220673 RGD:1600535 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IMP RGD PMID:16177098 RGD:1578516 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Rab44 RAB44, member RAS oncogene family acts_upstream_of_or_within ISO MGI:6695900 (PMID:32238914) RGD PMID:32238914 NCBI chr20:7,164,576...7,198,473
Ensembl chr20:7,164,720...7,198,468
JBrowse link
G Slc18a2 solute carrier family 18 member A2 involved_in IEA
ISO
GO_REF:0000107
(PMID:10618388)
Ensembl
RGD
PMID:10618388 GO_REF:0000107 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Snap23 synaptosome associated protein 23 involved_in ISO
IEA
(PMID:18253931)
GO_REF:0000107
RGD
Ensembl
PMID:18253931 GO_REF:0000107 NCBI chr 3:107,514,088...107,546,177
Ensembl chr 3:107,514,131...107,544,320
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta IMP RGD PMID:12499633 RGD:1625716 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
JBrowse link
mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor acts_upstream_of
involved_in
ISO
IEA
(PMID:11454903)
GO_REF:0000107
RGD
Ensembl
PMID:11454903 GO_REF:0000107 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
JBrowse link
G Adora3 adenosine A3 receptor acts_upstream_of ISO MGI:2155986 (PMID:12817016) RGD PMID:12817016 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357
JBrowse link
G Cbl Cbl proto-oncogene IEP RGD PMID:18243321 RGD:11576314 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176
JBrowse link
G Cd300a Cd300a molecule acts_upstream_of ISO (PMID:12874256) RGD PMID:12874256 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674
JBrowse link
G Chga chromogranin A involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:21214543)
UniProt
Ensembl
RGD
PMID:21214543 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
JBrowse link
G Clnk cytokine-dependent hematopoietic cell linker involved_in ISO (PMID:10744659) RGD PMID:10744659 NCBI chr14:71,923,894...72,101,180
Ensembl chr14:71,873,105...72,101,208
JBrowse link
G Cplx2 complexin 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
JBrowse link
G Fcer1a Fc epsilon receptor Ia involved_in
acts_upstream_of
ISO (PMID:8551243)
(PMID:9000133)
RGD PMID:8551243 PMID:9000133 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of ISO MGI:2384004 (PMID:14764707) RGD PMID:14764707 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Gpr15lg G protein-coupled receptor 15 ligand involved_in ISO
ISS
(PMID:35704588)
GO_REF:0000024
RGD
UniProt
PMID:35704588 GO_REF:0000024 NCBI chr16:12,868,270...12,875,876
Ensembl chr16:12,868,270...12,875,876
JBrowse link
G Grp gastrin releasing peptide involved_in ISS
ISO
GO_REF:0000024
(PMID:21933692)
UniProt
RGD
PMID:21933692 GO_REF:0000024 NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061
JBrowse link
G Ighe immunoglobulin heavy constant epsilon involved_in ISO (PMID:33840121), (PMID:8551243) RGD PMID:8551243 PMID:33840121
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (PMID:20100931) RGD PMID:20100931 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Lat linker for activation of T cells involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578
JBrowse link
G Lat2 linker for activation of T cells family, member 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr12:22,104,173...22,118,294
Ensembl chr12:22,104,219...22,118,288
JBrowse link
G Milr1 mast cell immunoglobulin-like receptor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:20526344)
UniProt
RGD
PMID:20526344 GO_REF:0000024 NCBI chr10:91,684,288...91,705,284
Ensembl chr10:91,687,831...91,705,282
JBrowse link
G Mrgprx2 MAS related GPR family member X2 involved_in ISO (PMID:22069323) RGD PMID:22069323 NCBI chr 1:98,116,192...98,135,534 JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:24586680)
UniProt
RGD
PMID:24586680 GO_REF:0000024 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Pla2g3 phospholipase A2, group III acts_upstream_of_or_within ISO MGI:4461174 (PMID:23624557) RGD PMID:23624557 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913
JBrowse link
G Ptgdrl1 prostaglandin D2 receptor-like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:18,072,357...18,081,452
Ensembl chr15:18,072,361...18,081,437
JBrowse link
G Ptgds prostaglandin D2 synthase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
JBrowse link
G Rab44 RAB44, member RAS oncogene family acts_upstream_of_or_within ISO MGI:6695900 (PMID:32238914) RGD PMID:32238914 NCBI chr20:7,164,576...7,198,473
Ensembl chr20:7,164,720...7,198,468
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of ISO MGI:3051384 (PMID:15235600) RGD PMID:15235600 NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2386261 (PMID:17190838)
Ensembl
RGD
PMID:17190838 GO_REF:0000107 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G Scn11a sodium voltage-gated channel alpha subunit 11 involved_in IEA
ISO
GO_REF:0000107
MGI:5608917 (PMID:31534133)
Ensembl
RGD
PMID:31534133 GO_REF:0000107 NCBI chr 8:119,495,550...119,567,044
Ensembl chr 8:119,496,769...119,567,044
JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:2384078 (PMID:9000133)
Ensembl
RGD
PMID:9000133 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
G Tac4 tachykinin precursor 4 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:80,207,824...80,216,156
Ensembl chr10:80,207,610...80,216,156
JBrowse link
negative regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule involved_in
acts_upstream_of_or_within
ISO (PMID:16339535)
(PMID:12874256)
RGD PMID:12874256 PMID:16339535 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674
JBrowse link
G Cd84 CD84 molecule involved_in ISO (PMID:22068234) RGD PMID:22068234 NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076
JBrowse link
G Foxf1 forkhead box F1 acts_upstream_of_or_within ISO MGI:2179135 (PMID:18421012) RGD PMID:18421012 NCBI chr19:49,153,949...49,157,741
Ensembl chr19:49,153,699...49,157,738
JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2653910 (PMID:15944273)
Ensembl
RGD
PMID:15944273 GO_REF:0000107 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:24465902) RGD PMID:24465902 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:3051384 (PMID:15235600) RGD PMID:15235600 NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744
JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide A involved_in IDA PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Pla2g3 phospholipase A2, group III involved_in ISO (PMID:23624557) RGD PMID:23624557 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913
JBrowse link
G Snx4 sorting nexin 4 involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr11:67,460,872...67,518,143
Ensembl chr11:67,460,870...67,518,174
JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr12:16,728,486...16,764,261
Ensembl chr12:16,728,524...16,764,097
JBrowse link
G Vamp8 vesicle-associated membrane protein 8 involved_in IEA
ISO
GO_REF:0000107
(PMID:18253931)
Ensembl
RGD
PMID:18253931 GO_REF:0000107 NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897
JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:11454903)
GO_REF:0000107
RGD
Ensembl
PMID:11454903 GO_REF:0000107 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
JBrowse link
G Adora3 adenosine A3 receptor acts_upstream_of_or_within ISO MGI:2155986 (PMID:12817016) RGD PMID:12817016 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IMP RGD PMID:18209484 RGD:5130941 NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481
JBrowse link
G Fcer1a Fc epsilon receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) RGD PMID:9000133 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:2384004 (PMID:14764707) RGD PMID:14764707 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO
GO_REF:0000024
(PMID:21746961)
UniProt
RGD
PMID:21746961 GO_REF:0000024 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326
JBrowse link
G Gab2 GRB2-associated binding protein 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:11449275)
UniProt
RGD
PMID:11449275 GO_REF:0000024 NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031
JBrowse link
G Gata1 GATA binding protein 1 IMP RGD PMID:22390417 RGD:9587812 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Gata2 GATA binding protein 2 IMP RGD PMID:22390417 RGD:9587812 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Il13 interleukin 13 acts_upstream_of_or_within ISO MGI:1931804|MGI:96556 (PMID:15944273) RGD PMID:15944273 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO MGI:1857195|MGI:96541 (PMID:15944273) RGD PMID:15944273 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO MGI:1861951 (PMID:15944273) RGD PMID:15944273 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Ms4a2 membrane spanning 4-domains A2 IMP RGD PMID:16177098 RGD:1578516 NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310
JBrowse link
G Nppc natriuretic peptide C involved_in IDA PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
JBrowse link
G Pld2 phospholipase D2 IMP RGD PMID:16861349 RGD:2299903 NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808
JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (PMID:17346996) RGD PMID:17346996 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391
JBrowse link
G Stxbp1 syntaxin binding protein 1 IMP RGD PMID:23487749 RGD:12904029 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369
JBrowse link
G Stxbp2 syntaxin binding protein 2 IMP RGD PMID:23487749 RGD:12904029 NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458
JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in
IMP
ISO
IEA
MGI:2384078 (PMID:9000133)
GO_REF:0000107
RGD
Ensembl
PMID:9000133 PMID:16861349 GO_REF:0000107, RGD:2299903 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snx6 sorting nexin 6 NOT|involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr 6:72,230,950...72,274,157
Ensembl chr 6:72,229,870...72,315,911
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 NOT|involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809
JBrowse link
G Vamp3 vesicle-associated membrane protein 3 NOT|involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr 5:161,498,109...161,508,704
Ensembl chr 5:161,498,109...161,508,751
JBrowse link
regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ferry3 FERRY endosomal RAB5 effector complex subunit 3 involved_in IDA
IBA
PMID:25122211
GO_REF:0000033
GO_Central PMID:25122211 GO_REF:0000033, RGD:10047193 NCBI chr 4:159,772,693...159,809,322
Ensembl chr 4:159,772,786...159,806,382
JBrowse link
G Fes FES proto-oncogene, tyrosine kinase involved_in ISO (PMID:19001085) RGD PMID:19001085 NCBI chr 1:134,337,698...134,346,934
Ensembl chr 1:134,337,698...134,346,934
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO
GO_REF:0000024
(PMID:16272347)
UniProt
RGD
PMID:16272347 GO_REF:0000024 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in IEA
ISO
GO_REF:0000107
(PMID:21063107)
Ensembl
RGD
PMID:21063107 GO_REF:0000107 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Rac2 Rac family small GTPase 2 involved_in ISO (PMID:10843388) RGD PMID:10843388 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720
JBrowse link
G Stxbp2 syntaxin binding protein 2 IMP RGD PMID:12482918 RGD:2312429 NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458
JBrowse link
G Unc13d unc-13 homolog D involved_in ISO (PMID:15548590) RGD PMID:15548590 NCBI chr10:101,296,755...101,311,513
Ensembl chr10:101,296,776...101,311,687
JBrowse link
serotonin secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule acts_upstream_of_or_within ISO (PMID:12874256) RGD PMID:12874256 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674
JBrowse link
G Slc18a2 solute carrier family 18 member A2 involved_in IEA
ISO
GO_REF:0000107
(PMID:10618388)
Ensembl
RGD
PMID:10618388 GO_REF:0000107 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20052
    immune system process 2995
      immune effector process 743
        leukocyte mediated immunity 488
          myeloid leukocyte mediated immunity 133
            mast cell mediated immunity 66
              mast cell degranulation + 63
              type I hypersensitivity mediated by mast cells 0
paths to the root