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ONTOLOGY REPORT - ANNOTATIONS


Term:myeloid leukocyte mediated immunity
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Accession:GO:0002444 term browser browse the term
Definition:Any process involved in the carrying out of an immune response by a myeloid leukocyte.
Synonyms:exact_synonym: myeloid leucocyte immune effector process;   myeloid leucocyte mediated immunity;   myeloid leukocyte immune effector process


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antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCGR1A Fc fragment of IgG receptor Ia involved_in IEA
ISO
(MGI:2679189|PMID:11911823)
(MGI:2664488|PMID:11911824)
Ensembl
MGI
PMID:11911823 PMID:11911824 GO_REF:0000107 MGI:2664488 MGI:2679189 NCBI chr17:59,073,139...59,102,023
Ensembl chr17:59,092,933...59,102,015
JBrowse link
basophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PI4K2A phosphatidylinositol 4-kinase type 2 alpha ISO RGD PMID:17122963 RGD:2306407 NCBI chr28:10,890,654...10,921,898 JBrowse link
eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL3 chemokine (C-C motif) ligand 3 involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:37,693,711...37,695,137
Ensembl chr 9:37,686,480...37,695,573
JBrowse link
G VAMP2 vesicle associated membrane protein 2 involved_in ISO (PMID:16677249) UniProt PMID:16677249 NCBI chr 5:32,975,372...32,977,967 JBrowse link
G VAMP7 vesicle associated membrane protein 7 involved_in ISO PMID:14993220
(PMID:16677249)
UniProt PMID:14993220 PMID:16677249 RGD:8553828 NCBI chr  X:123,717,524...123,783,781
Ensembl chr  X:123,717,446...123,783,014
JBrowse link
G VAMP8 vesicle associated membrane protein 8 NOT|involved_in ISO (PMID:16677249) UniProt PMID:16677249 NCBI chr17:39,497,628...39,501,734
Ensembl chr17:39,497,785...39,501,739
JBrowse link
eosinophil mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRAF3IP2 TRAF3 interacting protein 2 involved_in ISO
IEA
(MGI:3830744|PMID:19155511) MGI
Ensembl
PMID:19155511 GO_REF:0000107 MGI:3830744 NCBI chr12:68,029,861...68,070,901
Ensembl chr12:68,030,197...68,058,518
JBrowse link
histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA3 adenosine A3 receptor ISO (MGI:2664591|PMID:12817016) MGI PMID:12817016 MGI:2664591 NCBI chr17:63,895,408...63,898,666
Ensembl chr17:63,895,408...63,898,666
JBrowse link
G BTK Bruton tyrosine kinase ISO RGD PMID:12220673 RGD:1600535 NCBI chr  X:75,270,952...75,302,663
Ensembl chr  X:75,270,979...75,302,562
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:16177098 RGD:1578516 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507
JBrowse link
G SNAP23 synaptosome associated protein 23 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:9,453,931...9,493,506
Ensembl chr30:9,456,084...9,492,329
JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta ISO RGD PMID:12499633 RGD:1625716 NCBI chr13:2,729,404...2,764,422 JBrowse link
mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBL Cbl proto-oncogene ISO RGD PMID:18243321 RGD:11576314 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956
JBrowse link
G CHGA chromogranin A involved_in ISO (PMID:21214543) UniProt PMID:21214543 NCBI chr 8:1,970,966...1,973,511 JBrowse link
G CLNK cytokine dependent hematopoietic cell linker involved_in IEA
ISO
(MGI:2179131|PMID:10744659) Ensembl
UniProt
PMID:10744659 GO_REF:0000107 MGI:2179131 NCBI chr 3:68,929,239...69,083,777
Ensembl chr 3:68,881,358...69,080,263
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase involved_in ISS UniProt GO_REF:0000024 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029
JBrowse link
G MILR1 mast cell immunoglobulin like receptor 1 involved_in IEA
ISO
(MGI:4461821|PMID:20526344) InterPro
UniProt
PMID:20526344 GO_REF:0000002 MGI:4461821 NCBI chr 9:12,251,085...12,266,608
Ensembl chr 9:12,251,186...12,266,605
JBrowse link
G MRGPRX2 MAS related GPR family member X2 involved_in ISO (PMID:22069323) UniProt PMID:22069323 NCBI chr21:41,195,255...41,235,734 JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 ISO (MGI:5586645|PMID:24586680) UniProt PMID:24586680 MGI:5586645 NCBI chr11:56,806,506...56,846,997
Ensembl chr11:56,812,804...56,847,689
JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA
ISO
(MGI:5492190|PMID:23624557) Ensembl
MGI
PMID:23624557 GO_REF:0000107 MGI:5492190 NCBI chr26:24,127,074...24,132,508
Ensembl chr26:24,128,005...24,132,508
JBrowse link
G PTGDS prostaglandin D2 synthase involved_in IEA UniProt GO_REF:0000043 NCBI chr 9:48,647,334...48,650,608
Ensembl chr 9:48,646,255...48,669,814
JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in IEA
ISO
(MGI:3758152|PMID:17190838) Ensembl
MGI
PMID:17190838 GO_REF:0000107 MGI:3758152 NCBI chr30:5,840,901...5,914,804
Ensembl chr30:5,841,738...5,914,810
JBrowse link
mast cell mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SERPINB9 serpin family B member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:3,186,209...3,200,894
Ensembl chr35:3,190,543...3,199,690
JBrowse link
G SPON2 spondin 2 ISO (MGI:2686801|PMID:14691481) MGI PMID:14691481 MGI:2686801 NCBI chr 3:91,411,245...91,421,245 JBrowse link
negative regulation of eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR2 C-C motif chemokine receptor 2 involved_in IEA
ISO
(MGI:3699670|PMID:14662900) Ensembl
BHF-UCL
PMID:14662900 GO_REF:0000107 MGI:3699670 NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698
JBrowse link
negative regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300A CD300a molecule involved_in ISO (MGI:3721168|PMID:12874256)
(PMID:16339535)
MGI
UniProt
PMID:12874256 PMID:16339535 MGI:3721168 NCBI chr 9:5,952,428...5,976,328 JBrowse link
G CD84 CD84 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:21,702,788...21,727,373
Ensembl chr38:21,702,494...21,759,668
JBrowse link
G FOXF1 forkhead box F1 involved_in IEA
ISO
(MGI:4367570|PMID:18421012) Ensembl
MGI
PMID:18421012 GO_REF:0000107 MGI:4367570 NCBI chr 5:66,343,776...66,347,785
Ensembl chr 5:66,345,150...66,347,935
JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:17234154 RGD:1601626 NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773
JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 involved_in IEA
ISO
(MGI:3589858|PMID:15944273) Ensembl
MGI
PMID:15944273 GO_REF:0000107 MGI:3589858 NCBI chr  X:87,747,373...87,776,797
Ensembl chr  X:87,747,373...87,776,798
JBrowse link
G LGALS9 galectin 9 involved_in ISO (PMID:24465902) UniProt PMID:24465902 NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391
JBrowse link
G RABGEF1 RAB guanine nucleotide exchange factor 1 ISO (MGI:3050742|PMID:15235600) MGI PMID:15235600 MGI:3050742 NCBI chr 6:1,064,694...1,159,906
Ensembl chr 6:1,064,655...1,179,547
JBrowse link
negative regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABR ABR activator of RhoGEF and GTPase ISO (MGI:4366690|PMID:19703997) MGI PMID:19703997 MGI:4366690 NCBI chr 9:44,634,117...44,821,454
Ensembl chr 9:44,681,411...44,819,249
JBrowse link
G BCR BCR activator of RhoGEF and GTPase involved_in IEA
ISO
(MGI:4366690|PMID:19703997) Ensembl
MGI
PMID:19703997 GO_REF:0000107 MGI:4366690 NCBI chr26:27,856,280...27,980,923
Ensembl chr26:27,856,082...27,978,318
JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,253,849...42,269,497
Ensembl chr18:42,253,811...42,269,727
JBrowse link
neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA3 annexin A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:3,006,000...3,049,321
Ensembl chr32:3,005,788...3,049,049
JBrowse link
G MYO1F myosin IF ISO (MGI:3664353|PMID:17023661) MGI PMID:17023661 MGI:3664353 NCBI chr20:53,054,583...53,088,593
Ensembl chr20:53,054,585...53,089,115
JBrowse link
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing NOT ISO (MGI:6103777|PMID:28779020) UniProt PMID:28779020 MGI:6103777 NCBI chr37:16,537,095...16,620,427
Ensembl chr37:16,541,562...16,619,554
JBrowse link
G STX11 syntaxin 11 ISO (MGI:5460953|PMID:23042080) MGI PMID:23042080 MGI:5460953 NCBI chr 1:35,600,440...35,645,421
Ensembl chr 1:35,601,133...35,644,819
JBrowse link
G STXBP2 syntaxin binding protein 2 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr20:52,413,174...52,421,525
Ensembl chr20:52,413,191...52,421,517
JBrowse link
G STXBP3 syntaxin binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,947,639...42,998,297
Ensembl chr 6:42,948,236...43,053,027
JBrowse link
G VAMP2 vesicle associated membrane protein 2 NOT|involved_in ISO (PMID:16677249) UniProt PMID:16677249 NCBI chr 5:32,975,372...32,977,967 JBrowse link
G VAMP7 vesicle associated membrane protein 7 involved_in ISO PMID:14993220
(PMID:16677249)
UniProt PMID:14993220 PMID:16677249 RGD:8553828 NCBI chr  X:123,717,524...123,783,781
Ensembl chr  X:123,717,446...123,783,014
JBrowse link
G VAMP8 vesicle associated membrane protein 8 NOT|involved_in ISO (PMID:16677249) UniProt PMID:16677249 NCBI chr17:39,497,628...39,501,734
Ensembl chr17:39,497,785...39,501,739
JBrowse link
neutrophil mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme involved_in IEA
ISO
(MGI:3814166|PMID:17082641) Ensembl
MGI
PMID:17082641 GO_REF:0000107 MGI:3814166 NCBI chr 9:11,497,182...11,516,362
Ensembl chr 9:11,497,182...11,516,358
JBrowse link
G FCAR Fc fragment of IgA receptor involved_in ISO (PMID:25339672) CAFA PMID:25339672 NCBI chr 1:102,709,675...102,720,680 JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:10,313,782...10,340,652
Ensembl chr27:10,314,187...10,340,682
JBrowse link
G JAGN1 jagunal homolog 1 involved_in IEA
ISO
(MGI:5604054|PMID:25129145) Ensembl
UniProt
PMID:25129145 GO_REF:0000107 MGI:5604054 NCBI chr20:8,372,981...8,376,089
Ensembl chr20:8,373,316...8,376,085
JBrowse link
G KMT2E lysine methyltransferase 2E (inactive) involved_in IEA
ISO
(MGI:3834766|PMID:18854576) Ensembl
UniProt
PMID:18854576 GO_REF:0000107 MGI:3834766 NCBI chr18:15,240,631...15,332,850
Ensembl chr18:15,239,994...15,332,828
JBrowse link
G LOC100686711 CMRF35-like molecule 7 ISO (MGI:4821898|PMID:20566714) MGI PMID:20566714 MGI:4821898 NCBI chr 9:5,916,954...5,926,811 JBrowse link
G LYST lysosomal trafficking regulator ISO (MGI:68578|PMID:7988496) MGI PMID:7988496 MGI:68578 NCBI chr 4:4,106,869...4,296,042
Ensembl chr 4:4,089,837...4,294,593
JBrowse link
G MYO1F myosin IF ISO (MGI:3664353|PMID:17023661) MGI PMID:17023661 MGI:3664353 NCBI chr20:53,054,583...53,088,593
Ensembl chr20:53,054,585...53,089,115
JBrowse link
G PLA2G1B phospholipase A2 group IB involved_in ISO (PMID:16005851) BHF-UCL PMID:16005851 NCBI chr26:16,248,417...16,257,163
Ensembl chr26:16,248,409...16,257,178
JBrowse link
G WDR1 WD repeat domain 1 involved_in IEA
ISO
(MGI:3784948|PMID:17515402) Ensembl
UniProt
PMID:17515402 GO_REF:0000107 MGI:3784948 NCBI chr 3:69,305,731...69,348,183
Ensembl chr 3:69,305,731...69,348,177
JBrowse link
neutrophil-mediated killing of bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor involved_in ISO
IEA
(MGI:6478086|PMID:22419116) MGI
Ensembl
PMID:22419116 GO_REF:0000107 MGI:6478086 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534
JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta involved_in ISO
IEA
(MGI:6478086|PMID:22419116) MGI
Ensembl
PMID:22419116 GO_REF:0000107 MGI:6478086 NCBI chr 6:22,439,643...22,481,349
Ensembl chr 6:22,439,643...22,481,349
JBrowse link
neutrophil-mediated killing of fungus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ELANE elastase, neutrophil expressed involved_in IEA
ISO
(MGI:4353632|PMID:11907569) Ensembl
MGI
PMID:11907569 GO_REF:0000107 MGI:4353632 NCBI chr20:57,789,044...57,790,932
Ensembl chr20:57,788,062...57,790,932
JBrowse link
G NCF1 neutrophil cytosolic factor 1 ISO (MGI:4353632|PMID:11907569) MGI PMID:11907569 MGI:4353632 NCBI chr 6:5,702,222...5,719,515
Ensembl chr 6:5,605,694...5,719,458
JBrowse link
neutrophil-mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ELANE elastase, neutrophil expressed involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:57,789,044...57,790,932
Ensembl chr20:57,788,062...57,790,932
JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459
JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 ISO (MGI:5471912|PMID:23241959) MGI PMID:23241959 MGI:5471912 NCBI chr12:9,990,678...10,000,195
Ensembl chr12:9,990,679...10,000,236
JBrowse link
G TUSC2 tumor suppressor 2, mitochondrial calcium regulator ISO (MGI:5518492|PMID:24042119) MGI PMID:24042119 MGI:5518492 NCBI chr20:39,024,814...39,026,209 JBrowse link
neutrophil-mediated killing of gram-positive bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSG cathepsin G ISO (MGI:4353632|PMID:11907569) MGI PMID:11907569 MGI:4353632 NCBI chr 8:4,483,327...4,485,933
Ensembl chr 8:4,470,577...4,512,628
JBrowse link
G NCF1 neutrophil cytosolic factor 1 ISO (MGI:4353632|PMID:11907569) MGI PMID:11907569 MGI:4353632 NCBI chr 6:5,702,222...5,719,515
Ensembl chr 6:5,605,694...5,719,458
JBrowse link
positive regulation of eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180
JBrowse link
G STX4 syntaxin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:17,184,044...17,189,481
Ensembl chr 6:17,184,399...17,189,370
JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPPA natriuretic peptide A ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 2:84,406,317...84,408,115
Ensembl chr 2:84,396,073...84,408,385
JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA
ISO
(MGI:5492190|PMID:23624557) Ensembl
UniProt
PMID:23624557 GO_REF:0000107 MGI:5492190 NCBI chr26:24,127,074...24,132,508
Ensembl chr26:24,128,005...24,132,508
JBrowse link
G SNX4 sorting nexin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:28,413,586...28,468,546
Ensembl chr33:28,419,128...28,469,488
JBrowse link
G VAMP7 vesicle associated membrane protein 7 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr  X:123,717,524...123,783,781
Ensembl chr  X:123,717,446...123,783,014
JBrowse link
G VAMP8 vesicle associated membrane protein 8 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr17:39,497,628...39,501,734
Ensembl chr17:39,497,785...39,501,739
JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor ISO (MGI:3776334|PMID:11454903) MGI PMID:11454903 MGI:3776334 NCBI chr 5:39,884,375...39,908,214 JBrowse link
G ADORA3 adenosine A3 receptor ISO (MGI:2664591|PMID:12817016) MGI PMID:12817016 MGI:2664591 NCBI chr17:63,895,408...63,898,666
Ensembl chr17:63,895,408...63,898,666
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO RGD PMID:18209484 RGD:5130941 NCBI chr 9:9,708,696...9,763,281
Ensembl chr 9:9,714,204...9,763,402
JBrowse link
G FCER1A Fc fragment of IgE receptor Ia ISO (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chr38:22,683,478...22,688,842
Ensembl chr38:22,683,477...22,690,763
JBrowse link
G FCER1G Fc fragment of IgE receptor Ig involved_in IEA
ISO
(MGI:3029067|PMID:14764707) Ensembl
MGI
PMID:14764707 GO_REF:0000107 MGI:3029067 NCBI chr38:21,267,841...21,271,036
Ensembl chr38:21,268,001...21,270,940
JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase involved_in IEA
ISO
(MGI:5294498|PMID:21746961) Ensembl
UniProt
PMID:21746961 GO_REF:0000107 MGI:5294498 NCBI chr 2:72,678,858...72,692,417
Ensembl chr 2:72,680,675...72,690,251
JBrowse link
G GATA1 GATA binding protein 1 ISO RGD PMID:22390417 RGD:9587812 NCBI chr  X:41,991,321...41,998,319
Ensembl chr  X:41,971,582...41,998,303
JBrowse link
G GATA2 GATA binding protein 2 ISO RGD PMID:22390417 RGD:9587812 NCBI chr20:2,472,251...2,488,380
Ensembl chr20:2,473,912...2,480,991
JBrowse link
G IL13 interleukin 13 involved_in IEA
ISO
(MGI:3589858|PMID:15944273) Ensembl
MGI
PMID:15944273 GO_REF:0000107 MGI:3589858 NCBI chr11:20,957,870...20,961,391
Ensembl chr11:20,958,464...20,961,388
JBrowse link
G IL4 interleukin 4 involved_in IBA
ISO
(PMID:21873635)
(MGI:3589858|PMID:15944273)
GO_Central
MGI
PMID:15944273 PMID:21873635 MGI:3589858 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G IL4R interleukin 4 receptor ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291
JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chr21:50,439,133...50,456,785
Ensembl chr21:50,450,024...50,456,785
JBrowse link
G NARS2 asparaginyl-tRNA synthetase 2, mitochondrial ISO (MGI:2137187|PMID:11449275) UniProt PMID:11449275 MGI:2137187 NCBI chr21:20,277,707...20,413,624
Ensembl chr21:20,277,507...20,606,736
JBrowse link
G NPPC natriuretic peptide C ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr25:43,714,545...43,718,969
Ensembl chr25:43,717,939...43,718,996
JBrowse link
G PLD2 phospholipase D2 ISO RGD PMID:16861349 RGD:2299903 NCBI chr 5:31,755,881...31,767,131
Ensembl chr 5:31,756,433...31,767,066
JBrowse link
G SPHK2 sphingosine kinase 2 involved_in IEA
ISO
(MGI:3703830|PMID:17346996) Ensembl
UniProt
PMID:17346996 GO_REF:0000107 MGI:3703830 NCBI chr 1:107,681,425...107,689,790
Ensembl chr 1:107,680,599...107,689,707
JBrowse link
G STXBP1 syntaxin binding protein 1 ISO RGD PMID:23487749 RGD:12904029 NCBI chr 9:55,690,939...55,768,008
Ensembl chr 9:55,678,264...55,727,680
JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:23487749 RGD:12904029 NCBI chr20:52,413,174...52,421,525
Ensembl chr20:52,413,191...52,421,517
JBrowse link
G SYK spleen associated tyrosine kinase involved_in IBA
ISO
IEA
(PMID:21873635)
(MGI:85068|PMID:9000133)
GO_Central
MGI
RGD
Ensembl
PMID:9000133 PMID:16861349 PMID:21873635 GO_REF:0000107 MGI:85068 RGD:2299903 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583
JBrowse link
positive regulation of microglial cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGAM integrin subunit alpha M ISO (MGI:3812233|PMID:18685038) UniProt PMID:18685038 MGI:3812233 NCBI chr 6:16,944,062...16,996,525
Ensembl chr 6:16,808,971...16,996,286
JBrowse link
G NFKBID NFKB inhibitor delta involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:116,763,371...116,770,683
Ensembl chr 1:116,757,289...116,772,325
JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,253,849...42,269,497
Ensembl chr18:42,253,811...42,269,727
JBrowse link
G STAP1 signal transducing adaptor family member 1 involved_in IEA
ISO
(MGI:3831067|PMID:19100238) Ensembl
BHF-UCL
PMID:19100238 GO_REF:0000107 MGI:3831067 NCBI chr13:58,091,457...58,148,902
Ensembl chr13:58,091,477...58,133,711
JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in IBA
ISO
IEA
(PMID:21873635)
(MGI:3812233|PMID:18685038)
GO_Central
UniProt
Ensembl
PMID:18685038 PMID:21873635 GO_REF:0000107 MGI:3812233 NCBI chr 1:116,757,271...116,760,453
Ensembl chr 1:116,757,289...116,772,325
JBrowse link
positive regulation of myeloid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK4 calcium/calmodulin dependent protein kinase IV NOT|involved_in ISO (PMID:17909078) UniProt PMID:17909078 NCBI chr 3:1,174,975...1,369,640
Ensembl chr 3:1,180,401...1,369,803
JBrowse link
G DDX1 DEAD-box helicase 1 involved_in IEA
ISO
(MGI:5050760|PMID:21703541) Ensembl
UniProt
PMID:21703541 GO_REF:0000107 MGI:5050760 NCBI chr17:11,432,060...11,467,000
Ensembl chr17:11,432,136...11,466,990
JBrowse link
G DDX21 DExD-box helicase 21 involved_in IEA
ISO
(MGI:5050760|PMID:21703541) Ensembl
UniProt
PMID:21703541 GO_REF:0000107 MGI:5050760 NCBI chr 4:20,109,719...20,134,586
Ensembl chr 4:20,109,778...20,132,338
JBrowse link
G DDX58 DExD/H-box helicase 58 involved_in IEA
ISO
(MGI:5050760|PMID:21703541) Ensembl
UniProt
PMID:21703541 GO_REF:0000107 MGI:5050760 NCBI chr11:49,764,252...49,799,626
Ensembl chr11:49,764,267...49,799,527
JBrowse link
G DHX36 DEAH-box helicase 36 involved_in IEA
ISO
(MGI:5050760|PMID:21703541) Ensembl
UniProt
PMID:21703541 GO_REF:0000107 MGI:5050760 NCBI chr23:48,404,351...48,456,360
Ensembl chr23:48,407,316...48,456,654
JBrowse link
G MAVS mitochondrial antiviral signaling protein ISO (MGI:5050760|PMID:21703541) UniProt PMID:21703541 MGI:5050760 NCBI chr24:17,510,209...17,529,286
Ensembl chr24:17,512,761...17,523,807
JBrowse link
G TICAM1 toll like receptor adaptor molecule 1 involved_in IBA
ISO
(PMID:21873635)
(MGI:5050760|PMID:21703541)
GO_Central
UniProt
PMID:21703541 PMID:21873635 MGI:5050760 NCBI chr20:54,948,237...54,961,996
Ensembl chr20:54,959,525...54,961,780
JBrowse link
positive regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD177 CD177 molecule involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:111,693,234...111,698,879
Ensembl chr 1:111,693,005...111,698,742
JBrowse link
G ITGAM integrin subunit alpha M involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:16,944,062...16,996,525
Ensembl chr 6:16,808,971...16,996,286
JBrowse link
G ITGB2 integrin subunit beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr31:38,520,733...38,547,003
Ensembl chr31:38,521,103...38,547,018
JBrowse link
G PTAFR platelet activating factor receptor ISO RGD PMID:2829894 RGD:10041060 NCBI chr 2:72,225,386...72,256,353
Ensembl chr 2:72,225,386...72,256,352
JBrowse link
positive regulation of neutrophil mediated killing of fungus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG1 arginase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:242,717...255,736
Ensembl chr12:242,714...255,305
JBrowse link
G POMC proopiomelanocortin involved_in ISO (PMID:10670585) UniProt PMID:10670585 NCBI chr17:19,431,396...19,438,247
Ensembl chr17:19,431,585...19,434,440
JBrowse link
positive regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180
JBrowse link
positive regulation of type IIa hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA
ISO
(MGI:2177393|PMID:11901193) Ensembl
MGI
PMID:11901193 GO_REF:0000107 MGI:2177393 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761
JBrowse link
G FCER1G Fc fragment of IgE receptor Ig involved_in IEA
ISO
(MGI:2177393|PMID:11901193), (MGI:2664488|PMID:11911824)
(MGI:2383973|PMID:8976192)
Ensembl
MGI
PMID:8976192 PMID:11901193 PMID:11911824 GO_REF:0000107 MGI:2177393 MGI:2383973 MGI:2664488 NCBI chr38:21,267,841...21,271,036
Ensembl chr38:21,268,001...21,270,940
JBrowse link
G FCGR1A Fc fragment of IgG receptor Ia involved_in IEA
ISO
(MGI:2664488|PMID:11911824) Ensembl
MGI
PMID:11911824 GO_REF:0000107 MGI:2664488 NCBI chr17:59,073,139...59,102,023
Ensembl chr17:59,092,933...59,102,015
JBrowse link
positive regulation of type III hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase ISO RGD PMID:22228807 RGD:11040701 NCBI chr  X:75,270,952...75,302,663
Ensembl chr  X:75,270,979...75,302,562
JBrowse link
G FCER1G Fc fragment of IgE receptor Ig involved_in IEA
ISO
(MGI:2383973|PMID:8976192) Ensembl
MGI
PMID:8976192 GO_REF:0000107 MGI:2383973 NCBI chr38:21,267,841...21,271,036
Ensembl chr38:21,268,001...21,270,940
JBrowse link
G FCGR1A Fc fragment of IgG receptor Ia involved_in IEA
ISO
(MGI:2679189|PMID:11911823) Ensembl
MGI
PMID:11911823 GO_REF:0000107 MGI:2679189 NCBI chr17:59,073,139...59,102,023
Ensembl chr17:59,092,933...59,102,015
JBrowse link
regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNX6 sorting nexin 6 NOT|involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr 8:13,460,676...13,520,282
Ensembl chr 8:13,460,947...13,520,423
JBrowse link
G VAMP2 vesicle associated membrane protein 2 NOT|involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr 5:32,975,372...32,977,967 JBrowse link
G VAMP3 vesicle associated membrane protein 3 NOT|involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr 5:61,430,711...61,440,626
Ensembl chr 5:61,430,740...61,439,063
JBrowse link
regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRE2 adhesion G protein-coupled receptor E2 involved_in ISO (PMID:26841242) UniProt PMID:26841242 NCBI chr20:47,929,357...47,968,525
Ensembl chr20:47,873,897...47,968,525
JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr25:26,336,253...26,357,494
Ensembl chr25:26,336,892...26,358,015
JBrowse link
G C27H12orf4 chromosome 27 C12orf4 homolog involved_in IBA
ISO
(PMID:21873635)
PMID:25122211
GO_Central
UniProt
PMID:21873635 PMID:25122211 RGD:10047193 NCBI chr27:40,341,944...40,388,424
Ensembl chr27:40,343,672...40,388,031
JBrowse link
G FER FER tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:2,863,804...3,295,999
Ensembl chr 3:2,867,726...3,295,999
JBrowse link
G FES FES proto-oncogene, tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:53,346,975...53,356,547
Ensembl chr 3:53,347,012...53,356,516
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IBA
ISO
IEA
(PMID:21873635)
(MGI:3703139|PMID:16272347)
GO_Central
UniProt
Ensembl
PMID:16272347 PMID:21873635 GO_REF:0000107 MGI:3703139 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA
ISO
(MGI:5298334|PMID:21063107) Ensembl
UniProt
PMID:21063107 GO_REF:0000107 MGI:5298334 NCBI chr 6:38,426,464...38,506,520
Ensembl chr 6:38,431,600...38,499,295
JBrowse link
G RAC2 Rac family small GTPase 2 involved_in IEA
ISO
(MGI:3655336|PMID:10843388) Ensembl
CACAO
PMID:10843388 GO_REF:0000107 MGI:3655336 NCBI chr10:27,295,597...27,311,864
Ensembl chr10:27,295,640...27,311,397
JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:12482918 RGD:2312429 NCBI chr20:52,413,174...52,421,525
Ensembl chr20:52,413,191...52,421,517
JBrowse link
G UNC13D unc-13 homolog D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,753,300...4,766,751
Ensembl chr 9:4,753,166...4,766,756
JBrowse link
regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRAM1 PML-RARA regulated adaptor molecule 1 ISO (MGI:3525750|PMID:15572693) MGI PMID:15572693 MGI:3525750 NCBI chr20:53,035,389...53,047,126 JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA
ISO
(MGI:4414596|PMID:19797524) Ensembl
UniProt
PMID:19797524 GO_REF:0000107 MGI:4414596 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583
JBrowse link
regulation of neutrophil mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNASE1 deoxyribonuclease 1 involved_in IEA
ISO
ISS
(MGI:6094744|PMID:29191910)
(PMID:29191910)
Ensembl
UniProt
UniProt
PMID:29191910 GO_REF:0000107 MGI:6094744 NCBI chr 6:37,596,735...37,599,953
Ensembl chr 6:37,595,911...37,599,827
JBrowse link
G DNASE1L3 deoxyribonuclease 1 like 3 involved_in IEA
ISO
(MGI:6094744|PMID:29191910) Ensembl
UniProt
PMID:29191910 GO_REF:0000107 MGI:6094744 NCBI chr20:32,350,138...32,379,240
Ensembl chr20:32,358,110...32,379,245
JBrowse link
serotonin secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300A CD300a molecule ISO (MGI:3721168|PMID:12874256) MGI PMID:12874256 MGI:3721168 NCBI chr 9:5,952,428...5,976,328 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16149
    immune system process 2320
      immune effector process 722
        leukocyte mediated immunity 351
          myeloid leukocyte mediated immunity 109
            basophil mediated immunity + 1
            eosinophil mediated immunity + 8
            mast cell mediated immunity + 57
            microglial cell mediated cytotoxicity + 5
            myeloid dendritic cell cytokine production + 7
            negative regulation of myeloid leukocyte mediated immunity + 11
            neutrophil mediated immunity + 40
            positive regulation of myeloid leukocyte mediated immunity + 23
            regulation of myeloid leukocyte mediated immunity + 68
            type II hypersensitivity + 3
            type III hypersensitivity + 3
paths to the root