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ONTOLOGY REPORT - ANNOTATIONS

Term:myeloid leukocyte mediated immunity
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Accession:GO:0002444 term browser browse the term
Definition:Any process involved in the carrying out of an immune response by a myeloid leukocyte.
Synonyms:exact_synonym: myeloid leucocyte immune effector process;   myeloid leucocyte mediated immunity;   myeloid leukocyte immune effector process

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basophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pi4k2a phosphatidylinositol 4-kinase type 2 alpha ISO RGD PMID:17122963 RGD:2306407 NCBI chrNW_004955507:3,729,947...3,761,703
Ensembl chrNW_004955507:3,730,071...3,756,880 		JBrowse link
eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1a Fc fragment of IgE receptor Ia involved_in ISO (PMID:8114916) UniProt PMID:8114916 NCBI chrNW_004955468:11,094,792...11,101,191
Ensembl chrNW_004955468:11,094,788...11,101,173 		JBrowse link
G Vamp2 vesicle associated membrane protein 2 involved_in ISO (PMID:16677249) UniProt PMID:16677249 NCBI chrNW_004955467:8,793,296...8,796,771
Ensembl chrNW_004955467:8,793,296...8,796,771 		JBrowse link
G Vamp7 vesicle associated membrane protein 7 involved_in ISO (PMID:16677249)
PMID:14993220		 UniProt PMID:14993220 PMID:16677249 RGD:8553828 NCBI chrNW_004955594:20,496...72,648
Ensembl chrNW_004955594:18,727...72,654 		JBrowse link
G Vamp8 vesicle associated membrane protein 8 NOT|involved_in ISO (PMID:16677249) UniProt PMID:16677249 NCBI chrNW_004955424:1,922,830...1,926,844
Ensembl chrNW_004955424:1,923,092...1,926,728 		JBrowse link
eosinophil mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Traf3ip2 TRAF3 interacting protein 2 involved_in ISO (PMID:19155511) MGI PMID:19155511 NCBI chrNW_004955411:36,328,152...36,363,614
Ensembl chrNW_004955411:36,326,926...36,363,288 		JBrowse link
histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase ISO RGD PMID:12220673 RGD:1600535 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:16177098 RGD:1578516 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142 		JBrowse link
G Rab44 RAB44, member RAS oncogene family acts_upstream_of_or_within ISO (PMID:32238914) MGI PMID:32238914 NCBI chrNW_004955437:6,223,281...6,250,068
Ensembl chrNW_004955437:6,220,228...6,246,898 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 involved_in ISO (MGI:1351429|PMID:10618388) UniProt PMID:10618388 MGI:1351429 NCBI chrNW_004955431:21,949,553...21,979,679
Ensembl chrNW_004955431:21,949,576...21,979,679 		JBrowse link
G Snap23 synaptosome associated protein 23 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004955416:9,191,123...9,225,103
Ensembl chrNW_004955416:9,190,623...9,225,103 		JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta ISO RGD PMID:12499633 RGD:1625716 NCBI chrNW_004955417:16,047,263...16,070,506
Ensembl chrNW_004955417:16,047,263...16,072,854 		JBrowse link
mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2b receptor acts_upstream_of ISO (PMID:11454903) MGI PMID:11454903 NCBI chrNW_004955467:1,342,271...1,363,149
Ensembl chrNW_004955467:1,342,271...1,363,138 		JBrowse link
G Cbl Cbl proto-oncogene ISO RGD PMID:18243321 RGD:11576314 NCBI chrNW_004955412:20,307,011...20,388,539
Ensembl chrNW_004955412:20,307,011...20,388,539 		JBrowse link
G Cd300a CD300a molecule acts_upstream_of ISO (PMID:12874256) MGI PMID:12874256 NCBI chrNW_004955553:1,335,854...1,356,001
Ensembl chrNW_004955553:1,336,227...1,460,376 		JBrowse link
G Chga chromogranin A involved_in ISO (PMID:21214543) UniProt PMID:21214543 NCBI chrNW_004955438:15,092,267...15,104,321
Ensembl chrNW_004955438:15,092,394...15,104,381 		JBrowse link
G Clnk cytokine dependent hematopoietic cell linker involved_in ISO (MGI:2179131|PMID:10744659) UniProt PMID:10744659 MGI:2179131 NCBI chrNW_004955549:2,166,891...2,375,902 JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia involved_in
acts_upstream_of		 ISO (PMID:8551243)
(PMID:9000133)		 UniProt
MGI		 PMID:8551243 PMID:9000133 NCBI chrNW_004955468:11,094,792...11,101,191
Ensembl chrNW_004955468:11,094,788...11,101,173 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of ISO (PMID:14764707) MGI PMID:14764707 NCBI chrNW_004955468:12,971,931...12,975,206
Ensembl chrNW_004955468:12,971,931...12,975,206 		JBrowse link
G Gpr15lg G protein-coupled receptor 15 ligand involved_in ISO (PMID:35704588) UniProt PMID:35704588 NCBI chrNW_004955510:3,697,163...3,703,108 JBrowse link
G Grp gastrin releasing peptide involved_in ISO (MGI:6872268|PMID:21933692) UniProt PMID:21933692 MGI:6872268 NCBI chrNW_004955402:43,382,608...43,393,452
Ensembl chrNW_004955402:43,382,552...43,393,463 		JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase involved_in ISO (PMID:20100931) UniProt PMID:20100931 NCBI chrNW_004955447:16,149,014...16,226,151
Ensembl chrNW_004955447:16,148,605...16,226,734 		JBrowse link
G Milr1 mast cell immunoglobulin like receptor 1 involved_in ISO (MGI:4461821|PMID:20526344) UniProt PMID:20526344 MGI:4461821 NCBI chrNW_004955478:7,416,609...7,429,817 JBrowse link
G Nr4a3 nuclear receptor subfamily 4 group A member 3 involved_in ISO (MGI:5586645|PMID:24586680) UniProt PMID:24586680 MGI:5586645 NCBI chrNW_004955419:25,779,368...25,817,445
Ensembl chrNW_004955419:25,779,178...25,818,706 		JBrowse link
G Pla2g3 phospholipase A2 group III acts_upstream_of_or_within ISO (PMID:23624557) MGI PMID:23624557 NCBI chrNW_004955455:5,314,520...5,320,151
Ensembl chrNW_004955455:5,315,450...5,320,053 		JBrowse link
G Rab44 RAB44, member RAS oncogene family acts_upstream_of_or_within ISO (PMID:32238914) MGI PMID:32238914 NCBI chrNW_004955437:6,223,281...6,250,068
Ensembl chrNW_004955437:6,220,228...6,246,898 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of ISO (PMID:15235600) MGI PMID:15235600 NCBI chrNW_004955456:8,648,925...8,716,337
Ensembl chrNW_004955456:8,674,469...8,718,821 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 acts_upstream_of_or_within ISO (PMID:17190838) MGI PMID:17190838 NCBI chrNW_004955416:5,494,030...5,561,608
Ensembl chrNW_004955416:5,494,030...5,561,614 		JBrowse link
G Scn11a sodium voltage-gated channel alpha subunit 11 involved_in ISO (PMID:31534133) MGI PMID:31534133 NCBI chrNW_004955427:24,917,709...25,109,499
Ensembl chrNW_004955427:24,989,615...25,109,550 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of ISO (PMID:9000133) MGI PMID:9000133 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581 		JBrowse link
mast cell mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ndst2 N-deacetylase and N-sulfotransferase 2 acts_upstream_of_or_within ISO (PMID:10466727)
(PMID:10466726)		 MGI PMID:10466726 PMID:10466727 NCBI chrNW_004955437:18,090,198...18,099,328
Ensembl chrNW_004955437:18,090,198...18,099,328 		JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within ISO (PMID:14691481) MGI PMID:14691481 NCBI chrNW_004955514:598,840...603,390
Ensembl chrNW_004955514:596,829...604,051 		JBrowse link
negative regulation of eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr2 C-C motif chemokine receptor 2 involved_in ISO (MGI:3699670|PMID:14662900) BHF-UCL PMID:14662900 MGI:3699670 NCBI chrNW_004955420:25,641,184...25,664,413 JBrowse link
negative regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a CD300a molecule involved_in
acts_upstream_of_or_within		 ISO (PMID:16339535)
(PMID:12874256)		 UniProt
MGI		 PMID:12874256 PMID:16339535 NCBI chrNW_004955553:1,335,854...1,356,001
Ensembl chrNW_004955553:1,336,227...1,460,376 		JBrowse link
G Cd84 CD84 molecule involved_in ISO (PMID:22068234) UniProt PMID:22068234 NCBI chrNW_004955468:12,280,467...12,313,976
Ensembl chrNW_004955468:12,281,686...12,313,912 		JBrowse link
G Foxf1 forkhead box F1 acts_upstream_of_or_within ISO (PMID:18421012) MGI PMID:18421012 NCBI chrNW_004955541:1,341,715...1,345,397
Ensembl chrNW_004955541:1,317,114...1,346,590 		JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:17234154 RGD:1601626 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004955490:708,144...758,195
Ensembl chrNW_004955490:709,446...758,272 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:24465902) UniProt PMID:24465902 NCBI chrNW_004955481:5,234,125...5,249,564 JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (PMID:15235600) MGI PMID:15235600 NCBI chrNW_004955456:8,648,925...8,716,337
Ensembl chrNW_004955456:8,674,469...8,718,821 		JBrowse link
negative regulation of microglial cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISO (MGI:3639805|PMID:16732273) UniProt PMID:16732273 MGI:3639805 NCBI chrNW_004955427:24,691,206...24,705,599
Ensembl chrNW_004955427:24,701,073...24,707,230 		JBrowse link
negative regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abr ABR activator of RhoGEF and GTPase acts_upstream_of_or_within ISO (PMID:19703997) MGI PMID:19703997 NCBI chrNW_004955481:2,503,309...2,710,667
Ensembl chrNW_004955481:2,503,315...2,654,244 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase acts_upstream_of_or_within ISO (PMID:19703997) MGI PMID:19703997 NCBI chrNW_004955455:7,598,794...7,727,386
Ensembl chrNW_004955455:7,598,794...7,727,386 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:6381024|PMID:30911105) ARUK-UCL PMID:30911105 MGI:6381024 NCBI chrNW_004955422:873,735...886,560
Ensembl chrNW_004955422:873,735...886,560 		JBrowse link
neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abr ABR activator of RhoGEF and GTPase acts_upstream_of ISO (PMID:19703997) MGI PMID:19703997 NCBI chrNW_004955481:2,503,309...2,710,667
Ensembl chrNW_004955481:2,503,315...2,654,244 		JBrowse link
G Anxa3 annexin A3 involved_in ISO (PMID:9550422) UniProt PMID:9550422 NCBI chrNW_004955433:2,981,113...3,043,894
Ensembl chrNW_004955433:2,977,513...3,044,446 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase acts_upstream_of ISO (PMID:19703997) MGI PMID:19703997 NCBI chrNW_004955455:7,598,794...7,727,386
Ensembl chrNW_004955455:7,598,794...7,727,386 		JBrowse link
G Myo1f myosin IF acts_upstream_of_or_within ISO (PMID:17023661) MGI PMID:17023661 NCBI chrNW_004955563:880,545...916,630
Ensembl chrNW_004955563:880,545...916,630 		JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing NOT|involved_in ISO (MGI:6103777|PMID:28779020) UniProt PMID:28779020 MGI:6103777 NCBI chrNW_004955457:6,749,226...6,841,855
Ensembl chrNW_004955457:6,748,534...6,842,489 		JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO (PMID:23042080) MGI PMID:23042080 NCBI chrNW_004955436:16,303,169...16,327,854
Ensembl chrNW_004955436:16,303,189...16,327,854 		JBrowse link
G Stxbp2 syntaxin binding protein 2 involved_in ISO (PMID:18588921) UniProt PMID:18588921 NCBI chrNW_004955563:1,617,621...1,624,441
Ensembl chrNW_004955563:1,617,621...1,624,441 		JBrowse link
G Stxbp3 syntaxin binding protein 3 involved_in ISO (PMID:18588921) UniProt PMID:18588921 NCBI chrNW_004955435:12,215,665...12,270,769
Ensembl chrNW_004955435:12,215,665...12,274,465 		JBrowse link
G Vamp2 vesicle associated membrane protein 2 NOT|involved_in ISO (PMID:16677249) UniProt PMID:16677249 NCBI chrNW_004955467:8,793,296...8,796,771
Ensembl chrNW_004955467:8,793,296...8,796,771 		JBrowse link
G Vamp7 vesicle associated membrane protein 7 involved_in ISO (PMID:16677249)
PMID:14993220		 UniProt PMID:14993220 PMID:16677249 RGD:8553828 NCBI chrNW_004955594:20,496...72,648
Ensembl chrNW_004955594:18,727...72,654 		JBrowse link
G Vamp8 vesicle associated membrane protein 8 NOT|involved_in ISO (PMID:16677249) UniProt PMID:16677249 NCBI chrNW_004955424:1,922,830...1,926,844
Ensembl chrNW_004955424:1,923,092...1,926,728 		JBrowse link
neutrophil mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card9 caspase recruitment domain family member 9 involved_in ISO (PMID:26679537)
(MGI:5919121|PMID:26679537), (MGI:5919639|PMID:25621893)		 UniProt PMID:25621893 PMID:26679537 MGI:5919121 MGI:5919639 NCBI chrNW_004955513:4,350,873...4,359,345
Ensembl chrNW_004955513:4,350,147...4,359,345 		JBrowse link
G Cd300lb CD300 molecule like family member b acts_upstream_of_or_within ISO (PMID:20566714) MGI PMID:20566714 NCBI chrNW_004955553:1,382,594...1,392,592
Ensembl chrNW_004955553:1,383,433...1,392,598 		JBrowse link
G Irak4 interleukin 1 receptor associated kinase 4 involved_in ISO (PMID:19663824) UniProt PMID:19663824 NCBI chrNW_004955500:3,010,505...3,039,090
Ensembl chrNW_004955500:3,010,505...3,051,986 		JBrowse link
G Jagn1 jagunal homolog 1 involved_in ISO (MGI:5604054|PMID:25129145) UniProt PMID:25129145 MGI:5604054 NCBI chrNW_004955561:1,388,592...1,392,107
Ensembl chrNW_004955561:1,388,592...1,392,107 		JBrowse link
G Kmt2e lysine methyltransferase 2E (inactive) involved_in ISO (MGI:3834766|PMID:18854576) UniProt PMID:18854576 MGI:3834766 NCBI chrNW_004955410:9,714,587...9,808,021 JBrowse link
G Lyst lysosomal trafficking regulator acts_upstream_of_or_within ISO (PMID:7988496) MGI PMID:7988496 NCBI chrNW_004955492:4,161,976...4,371,637
Ensembl chrNW_004955492:4,209,749...4,369,762 		JBrowse link
G Myo1f myosin IF acts_upstream_of_or_within ISO (PMID:17023661) MGI PMID:17023661 NCBI chrNW_004955563:880,545...916,630
Ensembl chrNW_004955563:880,545...916,630 		JBrowse link
G Pla2g1b phospholipase A2 group IB involved_in ISO (PMID:16005851) BHF-UCL PMID:16005851 NCBI chrNW_004955455:11,308,848...11,316,245
Ensembl chrNW_004955455:11,308,643...11,316,254 		JBrowse link
G Wdr1 WD repeat domain 1 involved_in ISO (MGI:3784948|PMID:17515402) UniProt PMID:17515402 MGI:3784948 NCBI chrNW_004955549:2,640,193...2,674,818
Ensembl chrNW_004955549:2,640,195...2,673,969 		JBrowse link
neutrophil-mediated killing of bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88 innate immune signal transduction adaptor acts_upstream_of_or_within ISO (PMID:22419116) MGI PMID:22419116 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta acts_upstream_of_or_within ISO (PMID:22419116) MGI PMID:22419116 NCBI chrNW_004955493:1,937,507...1,956,248
Ensembl chrNW_004955493:1,904,220...1,956,303 		JBrowse link
neutrophil-mediated killing of fungus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102018844 neutrophil elastase acts_upstream_of_or_within ISO (PMID:11907569) MGI PMID:11907569 NCBI chrNW_004955495:6,964,577...6,967,208
Ensembl chrNW_004955495:6,964,667...6,967,106 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO (PMID:11907569) MGI PMID:11907569 NCBI chrNW_004955456:13,353,780...13,363,956
Ensembl chrNW_004955456:13,354,011...13,363,891 		JBrowse link
neutrophil-mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dao D-amino acid oxidase involved_in ISO (PMID:25425233)
(MGI:7581102|PMID:25425233)		 UniProt PMID:25425233 MGI:7581102 NCBI chrNW_004955455:10,095,597...10,127,244
Ensembl chrNW_004955455:10,095,300...10,127,666 		JBrowse link
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator acts_upstream_of_or_within ISO (PMID:24042119) MGI PMID:24042119 NCBI chrNW_004955532:2,128,430...2,131,235
Ensembl chrNW_004955532:2,128,430...2,131,235 		JBrowse link
neutrophil-mediated killing of gram-positive bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ncf1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO (PMID:11907569) MGI PMID:11907569 NCBI chrNW_004955456:13,353,780...13,363,956
Ensembl chrNW_004955456:13,354,011...13,363,891 		JBrowse link
G Nlrp6 NLR family pyrin domain containing 6 acts_upstream_of_or_within ISO (PMID:30248149) MGI PMID:30248149 NCBI chrNW_004955476:11,755,489...11,762,781 JBrowse link
positive regulation of eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:11714832) UniProt PMID:11714832 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide A involved_in ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chrNW_004955486:2,061,196...2,062,805
Ensembl chrNW_004955486:2,060,735...2,063,003 		JBrowse link
G Pla2g3 phospholipase A2 group III involved_in ISO (PMID:23624557)
(MGI:5492190|PMID:23624557)		 UniProt PMID:23624557 MGI:5492190 NCBI chrNW_004955455:5,314,520...5,320,151
Ensembl chrNW_004955455:5,315,450...5,320,053 		JBrowse link
G Snx4 sorting nexin 4 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004955427:24,520,125...24,579,589
Ensembl chrNW_004955427:24,520,125...24,579,589 		JBrowse link
G Vamp7 vesicle associated membrane protein 7 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004955594:20,496...72,648
Ensembl chrNW_004955594:18,727...72,654 		JBrowse link
G Vamp8 vesicle associated membrane protein 8 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004955424:1,922,830...1,926,844
Ensembl chrNW_004955424:1,923,092...1,926,728 		JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2b receptor acts_upstream_of_or_within ISO (PMID:11454903) MGI PMID:11454903 NCBI chrNW_004955467:1,342,271...1,363,149
Ensembl chrNW_004955467:1,342,271...1,363,138 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO RGD PMID:18209484 RGD:5130941 NCBI chrNW_004955478:10,380,185...10,390,838
Ensembl chrNW_004955478:10,379,287...10,404,825 		JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) MGI PMID:9000133 NCBI chrNW_004955468:11,094,792...11,101,191
Ensembl chrNW_004955468:11,094,788...11,101,173 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:14764707) MGI PMID:14764707 NCBI chrNW_004955468:12,971,931...12,975,206
Ensembl chrNW_004955468:12,971,931...12,975,206 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:5294498|PMID:21746961) UniProt PMID:21746961 MGI:5294498 NCBI chrNW_004955452:6,840,274...6,863,460
Ensembl chrNW_004955452:6,841,802...6,863,542 		JBrowse link
G Gab2 GRB2 associated binding protein 2 involved_in ISO (MGI:2137187|PMID:11449275) UniProt PMID:11449275 MGI:2137187 NCBI chrNW_004955414:13,640,713...13,754,401
Ensembl chrNW_004955414:13,679,588...13,751,079 		JBrowse link
G Gata1 GATA binding protein 1 ISO RGD PMID:22390417 RGD:9587812 NCBI chrNW_004955543:334,581...342,042
Ensembl chrNW_004955543:334,061...342,061 		JBrowse link
G Gata2 GATA binding protein 2 ISO RGD PMID:22390417 RGD:9587812 NCBI chrNW_004955429:15,326,551...15,334,774
Ensembl chrNW_004955429:15,327,113...15,336,460 		JBrowse link
G Il13 interleukin 13 acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004955408:4,046,406...4,049,795 JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004955493:5,546,340...5,580,745
Ensembl chrNW_004955493:5,545,944...5,582,422 		JBrowse link
G Ms4a2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chrNW_004955511:4,377,894...4,400,797
Ensembl chrNW_004955511:4,380,502...4,400,852 		JBrowse link
G Nppc natriuretic peptide C involved_in ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chrNW_004955453:3,884,580...3,888,494
Ensembl chrNW_004955453:3,884,560...3,888,850 		JBrowse link
G Pld2 phospholipase D2 ISO RGD PMID:16861349 RGD:2299903 NCBI chrNW_004955467:10,239,177...10,250,516
Ensembl chrNW_004955467:10,239,177...10,250,890 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (MGI:3703830|PMID:17346996) UniProt PMID:17346996 MGI:3703830 NCBI chrNW_004955559:1,921,479...1,929,450
Ensembl chrNW_004955559:1,917,301...1,928,493 		JBrowse link
G Stxbp1 syntaxin binding protein 1 ISO RGD PMID:23487749 RGD:12904029 NCBI chrNW_004955419:963,829...1,000,759
Ensembl chrNW_004955419:963,829...1,000,759 		JBrowse link
G Stxbp2 syntaxin binding protein 2 ISO RGD PMID:23487749 RGD:12904029 NCBI chrNW_004955563:1,617,621...1,624,441
Ensembl chrNW_004955563:1,617,621...1,624,441 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within ISO (PMID:9000133) RGD
MGI		 PMID:9000133 PMID:16861349 RGD:2299903 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581 		JBrowse link
positive regulation of microglial cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgam integrin subunit alpha M involved_in ISO (MGI:3812233|PMID:18685038) UniProt PMID:18685038 MGI:3812233 NCBI chrNW_004955493:8,116,886...8,160,806
Ensembl chrNW_004955493:8,116,834...8,260,759 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:6093262|PMID:28628103) ARUK-UCL PMID:28628103 MGI:6093262 NCBI chrNW_004955422:873,735...886,560
Ensembl chrNW_004955422:873,735...886,560 		JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (MGI:3831067|PMID:19100238) BHF-UCL PMID:19100238 MGI:3831067 NCBI chrNW_004955447:5,292,708...5,345,214
Ensembl chrNW_004955447:5,293,227...5,330,187 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor TYROBP involved_in ISO (MGI:3812233|PMID:18685038) UniProt PMID:18685038 MGI:3812233 NCBI chrNW_004955468:2,673,657...2,677,633
Ensembl chrNW_004955468:2,673,980...2,677,321 		JBrowse link
positive regulation of myeloid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk4 calcium/calmodulin dependent protein kinase IV NOT|involved_in ISO (PMID:17909078) UniProt PMID:17909078 NCBI chrNW_004955418:3,664,352...3,887,175
Ensembl chrNW_004955418:3,664,479...3,887,175 		JBrowse link
G Ddx1 DEAD-box helicase 1 involved_in ISO (MGI:5050760|PMID:21703541) UniProt PMID:21703541 MGI:5050760 NCBI chrNW_004955487:9,085,950...9,117,599
Ensembl chrNW_004955487:9,085,918...9,119,979 		JBrowse link
G Ddx21 DExD-box helicase 21 involved_in ISO (MGI:5050760|PMID:21703541) UniProt PMID:21703541 MGI:5050760 NCBI chrNW_004955437:22,050,029...22,071,213
Ensembl chrNW_004955437:22,050,937...22,071,118 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (MGI:5050760|PMID:21703541) UniProt PMID:21703541 MGI:5050760 NCBI chrNW_004955448:5,634,072...5,676,272
Ensembl chrNW_004955448:5,634,072...5,676,319 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (MGI:5050760|PMID:21703541) UniProt PMID:21703541 MGI:5050760 NCBI chrNW_004955415:14,691,918...14,704,782
Ensembl chrNW_004955415:14,695,438...14,703,672 		JBrowse link
G Rigi RNA sensor RIG-I involved_in ISO (MGI:5050760|PMID:21703541) UniProt PMID:21703541 MGI:5050760 NCBI chrNW_004955472:3,093,895...3,135,524
Ensembl chrNW_004955472:3,093,939...3,133,987 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 involved_in ISO (MGI:5050760|PMID:21703541) UniProt PMID:21703541 MGI:5050760 NCBI chrNW_004955495:4,197,083...4,204,999
Ensembl chrNW_004955495:4,202,372...4,204,513 		JBrowse link
positive regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd177 CD177 molecule involved_in ISO (PMID:21193407) UniProt PMID:21193407 NCBI chrNW_004955555:1,106,722...1,120,756 JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (PMID:21193407) UniProt PMID:21193407 NCBI chrNW_004955493:8,116,886...8,160,806
Ensembl chrNW_004955493:8,116,834...8,260,759 		JBrowse link
G Itgb2 integrin subunit beta 2 involved_in ISO (PMID:21193407) UniProt PMID:21193407 NCBI chrNW_004955407:41,779,849...41,805,637
Ensembl chrNW_004955407:41,777,777...41,800,201 		JBrowse link
G Ptafr platelet activating factor receptor ISO RGD PMID:2829894 RGD:10041060 NCBI chrNW_004955452:7,309,854...7,345,579
Ensembl chrNW_004955452:7,311,901...7,312,929 		JBrowse link
positive regulation of neutrophil mediated killing of fungus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO (PMID:15546957) UniProt PMID:15546957 NCBI chrNW_004955436:12,235,767...12,247,817
Ensembl chrNW_004955436:12,235,767...12,251,972 		JBrowse link
G Pomc proopiomelanocortin involved_in ISO (PMID:10670585) UniProt PMID:10670585 NCBI chrNW_004955469:7,217,233...7,220,401
Ensembl chrNW_004955469:7,217,363...7,220,386 		JBrowse link
positive regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:21501162) UniProt PMID:21501162 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
positive regulation of type IIa hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 acts_upstream_of_or_within ISO (PMID:11901193) MGI PMID:11901193 NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:8976192)
(PMID:11901193), (PMID:11911824)		 MGI PMID:8976192 PMID:11901193 PMID:11911824 NCBI chrNW_004955468:12,971,931...12,975,206
Ensembl chrNW_004955468:12,971,931...12,975,206 		JBrowse link
positive regulation of type III hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase ISO RGD PMID:22228807 RGD:11040701 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:8976192) MGI PMID:8976192 NCBI chrNW_004955468:12,971,931...12,975,206
Ensembl chrNW_004955468:12,971,931...12,975,206 		JBrowse link
regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snx6 sorting nexin 6 NOT|involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004955409:26,323,940...26,353,675
Ensembl chrNW_004955409:26,319,951...26,352,994 		JBrowse link
G Vamp2 vesicle associated membrane protein 2 NOT|involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004955467:8,793,296...8,796,771
Ensembl chrNW_004955467:8,793,296...8,796,771 		JBrowse link
G Vamp3 vesicle associated membrane protein 3 NOT|involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004955486:5,103,228...5,112,157
Ensembl chrNW_004955486:5,103,106...5,112,176 		JBrowse link
regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ferry3 FERRY endosomal RAB5 effector complex subunit 3 involved_in ISO PMID:25122211 UniProt PMID:25122211 RGD:10047193 NCBI chrNW_004955413:2,298,514...2,335,308
Ensembl chrNW_004955413:2,298,970...2,335,237 		JBrowse link
G Fes FES proto-oncogene, tyrosine kinase involved_in ISO (PMID:19001085) UniProt PMID:19001085 NCBI chrNW_004955416:14,948,121...14,959,035
Ensembl chrNW_004955416:14,948,123...14,960,005 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:3703139|PMID:16272347) UniProt PMID:16272347 MGI:3703139 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (MGI:5298334|PMID:21063107) UniProt PMID:21063107 MGI:5298334 NCBI chrNW_004955442:14,685,089...14,772,870
Ensembl chrNW_004955442:14,685,153...14,772,870 		JBrowse link
G Rac2 Rac family small GTPase 2 involved_in ISO (MGI:3655336|PMID:10843388) CACAO PMID:10843388 MGI:3655336 NCBI chrNW_004955413:23,697,504...23,710,668
Ensembl chrNW_004955413:23,693,669...23,710,704 		JBrowse link
G Stxbp2 syntaxin binding protein 2 ISO RGD PMID:12482918 RGD:2312429 NCBI chrNW_004955563:1,617,621...1,624,441
Ensembl chrNW_004955563:1,617,621...1,624,441 		JBrowse link
G Unc13d unc-13 homolog D involved_in ISO (PMID:15548590) UniProt PMID:15548590 NCBI chrNW_004955506:6,407,073...6,423,406
Ensembl chrNW_004955506:6,407,723...6,423,406 		JBrowse link
regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pram1 PML-RARA regulated adaptor molecule 1 acts_upstream_of_or_within ISO (PMID:15572693) MGI PMID:15572693 NCBI chrNW_004955563:924,365...933,198
Ensembl chrNW_004955563:926,765...933,183 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO (MGI:4414596|PMID:19797524) UniProt PMID:19797524 MGI:4414596 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581 		JBrowse link
regulation of neutrophil mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnase1 deoxyribonuclease 1 involved_in ISO (MGI:6094744|PMID:29191910) UniProt PMID:29191910 MGI:6094744 NCBI chrNW_004955442:13,733,107...13,736,527 JBrowse link
G Dnase1l3 deoxyribonuclease 1L3 involved_in ISO (MGI:6094744|PMID:29191910) UniProt PMID:29191910 MGI:6094744 NCBI chrNW_004955430:7,867,172...7,892,079
Ensembl chrNW_004955430:7,867,109...7,892,079 		JBrowse link
serotonin secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a CD300a molecule acts_upstream_of_or_within ISO (PMID:12874256) MGI PMID:12874256 NCBI chrNW_004955553:1,335,854...1,356,001
Ensembl chrNW_004955553:1,336,227...1,460,376 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 involved_in ISO (MGI:1351429|PMID:10618388) UniProt PMID:10618388 MGI:1351429 NCBI chrNW_004955431:21,949,553...21,979,679
Ensembl chrNW_004955431:21,949,576...21,979,679 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    immune system process 1980
      immune effector process 535
        leukocyte mediated immunity 320
          myeloid leukocyte mediated immunity 103
            basophil mediated immunity + 1
            eosinophil mediated immunity + 7
            mast cell mediated immunity + 56
            microglial cell mediated cytotoxicity + 5
            myeloid dendritic cell cytokine production + 7
            negative regulation of myeloid leukocyte mediated immunity + 12
            neutrophil mediated immunity + 38
            positive regulation of myeloid leukocyte mediated immunity + 20
            regulation of myeloid leukocyte mediated immunity + 62
            type II hypersensitivity + 2
            type III hypersensitivity + 2
paths to the root