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ONTOLOGY REPORT - ANNOTATIONS

Term:production of molecular mediator of immune response
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Accession:GO:0002440 term browser browse the term
Definition:The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.
Comment:Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
Synonyms:related_synonym: production of cellular mediator of immune response

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antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals4 galectin 4 acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955468:694,831...701,623
Ensembl chrNW_004955468:694,873...701,535 		JBrowse link
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:20056603) MGI PMID:20056603 NCBI chrNW_004955412:5,780,772...5,792,485
Ensembl chrNW_004955412:5,778,502...5,792,445 		JBrowse link
antibacterial peptide secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:11248802) MGI PMID:11248802 NCBI chrNW_004955412:5,780,772...5,792,485
Ensembl chrNW_004955412:5,778,502...5,792,445 		JBrowse link
B cell affinity maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase acts_upstream_of_or_within ISO (PMID:7680896) MGI PMID:7680896 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120 		JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 involved_in ISO (PMID:20543113) MGI PMID:20543113 NCBI chrNW_004955411:36,328,152...36,363,614
Ensembl chrNW_004955411:36,326,926...36,363,288 		JBrowse link
biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of ISO (PMID:15692051) MGI PMID:15692051 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
immunoglobulin heavy chain V-D-J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Polb DNA polymerase beta acts_upstream_of_or_within ISO (PMID:24388753) MGI PMID:24388753 NCBI chrNW_004955536:542,179...595,198
Ensembl chrNW_004955536:540,836...595,198 		JBrowse link
G Yy1 YY1 transcription factor involved_in ISO (PMID:23531880) MGI PMID:23531880 NCBI chrNW_004955438:21,341,374...21,377,674 JBrowse link
immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO RGD PMID:22981234 RGD:8696027 NCBI chrNW_004955454:7,733,697...7,890,896
Ensembl chrNW_004955454:7,733,978...7,890,867 		JBrowse link
immunoglobulin V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:16819554) MGI PMID:16819554 NCBI chrNW_004955421:16,595,445...17,075,923
Ensembl chrNW_004955421:16,595,471...17,075,923 		JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO (PMID:9823897) MGI PMID:9823897 NCBI chrNW_004955404:3,606,077...3,615,193
Ensembl chrNW_004955404:3,606,077...3,615,193 		JBrowse link
G Nhej1 non-homologous end joining factor 1 involved_in ISO (PMID:20558749) UniProt PMID:20558749 NCBI chrNW_004955453:14,278,773...14,362,167
Ensembl chrNW_004955453:14,281,069...14,363,876 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit acts_upstream_of_or_within ISO (PMID:9768755) MGI PMID:9768755 NCBI chrNW_004955454:7,733,697...7,890,896
Ensembl chrNW_004955454:7,733,978...7,890,867 		JBrowse link
G Tcf3 transcription factor 3 acts_upstream_of_or_within ISO (PMID:16428437) MGI PMID:16428437 NCBI chrNW_004955495:6,337,311...6,365,193
Ensembl chrNW_004955495:6,337,870...6,367,487 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (PMID:9875844) MGI PMID:9875844 NCBI chrNW_004955418:27,174,510...27,426,245
Ensembl chrNW_004955418:27,173,659...27,426,264 		JBrowse link
isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 acts_upstream_of ISO (PMID:25404367) MGI PMID:25404367 NCBI chrNW_004955481:6,986,128...7,031,113
Ensembl chrNW_004955481:6,986,502...7,030,742 		JBrowse link
G Batf basic leucine zipper ATF-like transcription factor involved_in ISO (MGI:4456325|PMID:20421391), (MGI:5004732|PMID:21572431) UniProt PMID:20421391 PMID:21572431 MGI:4456325 MGI:5004732 NCBI chrNW_004955523:42,365...66,103
Ensembl chrNW_004955523:42,218...66,103 		JBrowse link
G Cd40lg CD40 ligand involved_in ISO (MGI:3687427|PMID:7529792) UniProt PMID:7529792 MGI:3687427 NCBI chrNW_004955489:8,465,571...8,477,714
Ensembl chrNW_004955489:8,465,164...8,477,746 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit acts_upstream_of_or_within ISO (PMID:15280420) MGI PMID:15280420 NCBI chrNW_004955555:2,393,510...2,430,180
Ensembl chrNW_004955555:2,393,278...2,406,582 		JBrowse link
G Exo1 exonuclease 1 acts_upstream_of_or_within ISO (PMID:14716311) MGI PMID:14716311 NCBI chrNW_004955406:10,248,981...10,276,207
Ensembl chrNW_004955406:10,245,886...10,275,522 		JBrowse link
G Exosc3 exosome component 3 involved_in ISO (MGI:5009766|PMID:21255825) UniProt PMID:21255825 MGI:5009766 NCBI chrNW_004955419:28,683,896...28,692,006
Ensembl chrNW_004955419:28,683,896...28,693,395 		JBrowse link
G Exosc6 exosome component 6 involved_in ISO (MGI:5009766|PMID:21255825) UniProt PMID:21255825 MGI:5009766 NCBI chrNW_004955484:3,088,133...3,089,551
Ensembl chrNW_004955484:3,088,624...3,089,472 		JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO (PMID:17713479) MGI PMID:17713479 NCBI chrNW_004955404:3,606,077...3,615,193
Ensembl chrNW_004955404:3,606,077...3,615,193 		JBrowse link
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:12743174) MGI PMID:12743174 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within ISO (PMID:10430621)
(PMID:12743174)		 MGI PMID:10430621 PMID:12743174 NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO (PMID:17015724)
(PMID:16618598)		 MGI PMID:16618598 PMID:17015724 NCBI chrNW_004955441:14,451,207...14,471,316
Ensembl chrNW_004955441:14,451,307...14,471,227 		JBrowse link
G Nbn nibrin involved_in ISO (MGI:3529405|PMID:15668383) UniProt PMID:15668383 MGI:3529405 NCBI chrNW_004955417:6,840,916...6,880,479
Ensembl chrNW_004955417:6,839,312...6,880,133 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:25124037)
(PMID:31182790)		 MGI PMID:25124037 PMID:31182790 NCBI chrNW_004955427:3,350,174...3,358,609
Ensembl chrNW_004955427:3,350,174...3,360,379 		JBrowse link
G Rnf168 ring finger protein 168 involved_in ISO (MGI:4420833|PMID:20080757) UniProt PMID:20080757 MGI:4420833 NCBI chrNW_004955420:12,656,815...12,676,836
Ensembl chrNW_004955420:12,657,272...12,676,426 		JBrowse link
G Rnf8 ring finger protein 8 involved_in ISO (MGI:4420833|PMID:20080757) UniProt PMID:20080757 MGI:4420833 NCBI chrNW_004955437:5,807,592...5,832,213
Ensembl chrNW_004955437:5,809,082...5,832,057 		JBrowse link
G Sanbr SANT and BTB domain regulator of CSR involved_in ISO (MGI:6707280|PMID:33831416) UniProt PMID:33831416 MGI:6707280 NCBI chrNW_004955424:22,728,802...22,785,374
Ensembl chrNW_004955424:22,728,802...22,785,374 		JBrowse link
G Swap70 switching B cell complex subunit SWAP70 acts_upstream_of_or_within ISO (PMID:9642267) MGI PMID:9642267 NCBI chrNW_004955414:25,385,648...25,444,743
Ensembl chrNW_004955414:25,385,007...25,444,913 		JBrowse link
G Ung uracil DNA glycosylase acts_upstream_of_or_within ISO (PMID:17015724) MGI PMID:17015724 NCBI chrNW_004955455:10,266,989...10,282,196
Ensembl chrNW_004955455:10,266,989...10,282,196 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (PMID:17713479) MGI PMID:17713479 NCBI chrNW_004955418:27,174,510...27,426,245
Ensembl chrNW_004955418:27,173,659...27,426,264 		JBrowse link
isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr6 C-C motif chemokine receptor 6 involved_in ISO (MGI:5787846|PMID:27174992) UniProt PMID:27174992 MGI:5787846 NCBI chrNW_004955439:14,921,524...14,949,493
Ensembl chrNW_004955439:14,920,601...14,924,191 		JBrowse link
isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004955420:19,998,960...20,021,200
Ensembl chrNW_004955420:19,998,742...20,022,259 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of ISO (PMID:16275384) MGI PMID:16275384 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Il4 interleukin 4 acts_upstream_of ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004955458:4,833,417...4,847,956
Ensembl chrNW_004955458:4,833,515...4,843,273 		JBrowse link
isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) BHF-UCL PMID:16148103 NCBI chrNW_004955403:3,062,724...3,073,419
Ensembl chrNW_004955403:3,063,133...3,073,419 		JBrowse link
G Il4 interleukin 4 acts_upstream_of ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
negative regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink5 serine peptidase inhibitor Kazal type 5 involved_in ISO (MGI:3770082|PMID:17012259) UniProt PMID:17012259 MGI:3770082 NCBI chrNW_004955415:6,118,616...6,186,632 JBrowse link
negative regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 acts_upstream_of_or_within ISO (PMID:20060382) MGI PMID:20060382 NCBI chrNW_004955417:30,199,508...30,386,695
Ensembl chrNW_004955417:30,198,842...30,386,266 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO (PMID:12458630) BHF-UCL PMID:12458630 NCBI chrNW_004955412:18,170,331...18,172,298
Ensembl chrNW_004955412:18,170,331...18,172,298 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:12458630) BHF-UCL PMID:12458630 NCBI chrNW_004955468:12,977,956...12,979,282
Ensembl chrNW_004955468:12,977,956...12,979,753 		JBrowse link
G Il10 interleukin 10 involved_in ISO (PMID:10443688) BHF-UCL PMID:10443688 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10443688) BHF-UCL PMID:10443688 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
negative regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) BHF-UCL PMID:16020505 MGI:3719947 NCBI chrNW_004955524:3,399,895...3,412,018
Ensembl chrNW_004955524:3,401,642...3,411,643 		JBrowse link
negative regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 molecule involved_in ISO (MGI:4453395|PMID:20200274) ARUK-UCL PMID:20200274 MGI:4453395 NCBI chrNW_004955468:4,609,601...4,622,601
Ensembl chrNW_004955468:4,612,044...4,625,882 		JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb acts_upstream_of_or_within ISO (PMID:12385742) MGI PMID:12385742 NCBI chrNW_004955462:14,639,396...14,653,801 JBrowse link
G Ifnb1 interferon beta 1 ISO RGD PMID:10494101 RGD:401854240 NCBI chrNW_004955434:23,301,623...23,302,304 JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004955490:708,144...758,195
Ensembl chrNW_004955490:709,446...758,272 		JBrowse link
G Il33 interleukin 33 involved_in ISO (MGI:3775141|PMID:18268038) BHF-UCL PMID:18268038 MGI:3775141 NCBI chrNW_004955434:10,145,449...10,187,595
Ensembl chrNW_004955434:10,171,812...10,188,948 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO RGD PMID:22981234 RGD:8696027 NCBI chrNW_004955454:7,733,697...7,890,896
Ensembl chrNW_004955454:7,733,978...7,890,867 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (MGI:3840374|PMID:19328063) ParkinsonsUK-UCL PMID:19328063 MGI:3840374 NCBI chrNW_004955547:335,344...358,503
Ensembl chrNW_004955547:335,275...358,503 		JBrowse link
G Zpbp2 zona pellucida binding protein 2 acts_upstream_of_or_within ISO (PMID:29536159) MGI PMID:29536159 NCBI chrNW_004955451:14,571,707...14,579,890
Ensembl chrNW_004955451:14,571,556...14,579,948 		JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly(ADP-ribose) polymerase family member 3 involved_in ISO (MGI:6214451|PMID:26000965) UniProt PMID:26000965 MGI:6214451 NCBI chrNW_004955532:3,591,484...3,597,549
Ensembl chrNW_004955532:3,591,499...3,597,549 		JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004955420:19,998,960...20,021,200
Ensembl chrNW_004955420:19,998,742...20,022,259 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:16275384) MGI PMID:16275384 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (PMID:17137798) MGI PMID:17137798 NCBI chrNW_004955415:11,643,846...11,666,131
Ensembl chrNW_004955415:11,643,846...11,666,131 		JBrowse link
negative regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant acts_upstream_of_or_within ISO (PMID:11168643) MGI PMID:11168643 NCBI chrNW_004955495:2,418,113...2,421,181
Ensembl chrNW_004955495:2,418,364...2,421,538 		JBrowse link
G Atg9a autophagy related 9A acts_upstream_of_or_within ISO (PMID:24670807) MGI PMID:24670807 NCBI chrNW_004955453:14,203,798...14,214,760
Ensembl chrNW_004955453:14,206,065...14,213,729 		JBrowse link
G Axl AXL receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:16831897) MGI PMID:16831897 NCBI chrNW_004955555:189,445...218,509
Ensembl chrNW_004955555:189,174...218,565 		JBrowse link
G Cuedc2 CUE domain containing 2 acts_upstream_of_or_within ISO (PMID:24882011) MGI PMID:24882011 NCBI chrNW_004955485:7,969,389...7,977,073
Ensembl chrNW_004955485:7,975,190...7,976,875 		JBrowse link
G Epx eosinophil peroxidase acts_upstream_of_or_within ISO (PMID:16926417) MGI PMID:16926417 NCBI chrNW_004955451:4,818,809...4,828,913
Ensembl chrNW_004955451:4,818,809...4,828,913 		JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 involved_in ISO (MGI:2183694|PMID:12150927) BHF-UCL PMID:12150927 MGI:2183694 NCBI chrNW_004955458:12,839,995...12,880,285
Ensembl chrNW_004955458:12,846,237...12,879,316 		JBrowse link
G Nlrx1 NLR family member X1 acts_upstream_of_or_within ISO (PMID:21703540) MGI PMID:21703540 NCBI chrNW_004955412:20,275,767...20,287,414
Ensembl chrNW_004955412:20,275,917...20,287,414 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15220916) MGI PMID:15220916 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G Tgfb1 transforming growth factor beta 1 involved_in ISO (PMID:20875417) DFLAT PMID:20875417 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441 		JBrowse link
G Tgfb2 transforming growth factor beta 2 involved_in ISO (PMID:20875417) DFLAT PMID:20875417 NCBI chrNW_004955406:174,949...249,248
Ensembl chrNW_004955406:172,814...249,248 		JBrowse link
G Tgfb3 transforming growth factor beta 3 involved_in ISO (PMID:20875417) DFLAT PMID:20875417 NCBI chrNW_004955438:33,129...55,180
Ensembl chrNW_004955438:29,415...55,180 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO (PMID:16831897) MGI PMID:16831897 NCBI chrNW_004955410:22,003,981...22,005,483 JBrowse link
G Twist2 twist family bHLH transcription factor 2 acts_upstream_of_or_within ISO (PMID:16831897) MGI PMID:16831897 NCBI chrNW_004955542:1,959,765...2,000,665
Ensembl chrNW_004955542:1,959,765...2,000,665 		JBrowse link
negative regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within ISO (PMID:15950739) MGI PMID:15950739 NCBI chrNW_004955420:19,998,960...20,021,200
Ensembl chrNW_004955420:19,998,742...20,022,259 		JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:17234154 RGD:1601626 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (PMID:16533754) MGI PMID:16533754 NCBI chrNW_004955456:8,648,925...8,716,337
Ensembl chrNW_004955456:8,674,469...8,718,821 		JBrowse link
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd96 CD96 molecule acts_upstream_of_or_within ISO (PMID:24658051) MGI PMID:24658051 NCBI chrNW_004955427:11,971,051...12,057,185
Ensembl chrNW_004955427:11,971,021...12,059,171 		JBrowse link
negative regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in ISO (PMID:15466453)
(PMID:23169781)		 UniProt PMID:15466453 PMID:23169781 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Hfe homeostatic iron regulator involved_in ISO (PMID:24643698) BHF-UCL PMID:24643698 NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143 		JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (MGI:5700313|PMID:11477403) UniProt PMID:11477403 MGI:5700313 NCBI chrNW_004955468:12,336,744...12,383,917
Ensembl chrNW_004955468:12,334,307...12,370,334 		JBrowse link
G Smad7 SMAD family member 7 involved_in ISO (MGI:5634593|PMID:25642768) BHF-UCL PMID:25642768 MGI:5634593 NCBI chrNW_004955402:34,028,184...34,058,949
Ensembl chrNW_004955402:34,028,063...34,058,291 		JBrowse link
G Vsir V-set immunoregulatory receptor acts_upstream_of_or_within ISO (PMID:21383057) MGI PMID:21383057 NCBI chrNW_004955437:19,716,466...19,743,428 JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) BHF-UCL PMID:10887101 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO (MGI:5908339|PMID:19360123) UniProt PMID:19360123 MGI:5908339 NCBI chrNW_004955436:12,235,767...12,247,817
Ensembl chrNW_004955436:12,235,767...12,251,972 		JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:20554961) UniProt PMID:20554961 NCBI chrNW_004955434:23,301,623...23,302,304 JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:5543347|PMID:23616576)
(MGI:1354779|PMID:10761931)		 UniProt PMID:10761931 PMID:23616576 MGI:1354779 MGI:5543347 NCBI chrNW_004955451:13,315,237...13,317,888
Ensembl chrNW_004955451:13,315,859...13,325,937 		JBrowse link
positive regulation of antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:18167348) MGI PMID:18167348 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
positive regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klk5 kallikrein related peptidase 5 involved_in ISO (PMID:17012259) UniProt PMID:17012259 NCBI chrNW_004955558:1,512,478...1,520,522
Ensembl chrNW_004955558:1,511,818...1,520,613 		JBrowse link
G Klk7 kallikrein related peptidase 7 involved_in ISO (PMID:17012259) UniProt PMID:17012259 NCBI chrNW_004955558:1,490,884...1,494,843
Ensembl chrNW_004955558:1,490,120...1,494,993 		JBrowse link
G Pgc progastricsin involved_in ISO (PMID:12759353) UniProt PMID:12759353 NCBI chrNW_004955437:8,142,523...8,153,044
Ensembl chrNW_004955437:8,142,661...8,151,339 		JBrowse link
positive regulation of antimicrobial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17a interleukin 17A involved_in ISO (MGI:3828868|PMID:19144317) UniProt PMID:19144317 MGI:3828868 NCBI chrNW_004955411:5,896,435...5,899,911
Ensembl chrNW_004955411:5,896,702...5,900,962 		JBrowse link
G Il17f interleukin 17F involved_in ISO (MGI:3828868|PMID:19144317) UniProt PMID:19144317 MGI:3828868 NCBI chrNW_004955411:5,852,767...5,859,208
Ensembl chrNW_004955411:5,852,767...5,859,208 		JBrowse link
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15692051) MGI PMID:15692051 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
positive regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:11441110) UniProt PMID:11441110 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
G Ffar3 free fatty acid receptor 3 involved_in ISO (MGI:5575446|PMID:23665276) UniProt PMID:23665276 MGI:5575446 NCBI chrNW_004955468:4,627,686...4,634,499 JBrowse link
G Hk1 hexokinase 1 involved_in ISO (MGI:5790524|PMID:27374331) CAFA PMID:27374331 MGI:5790524 NCBI chrNW_004955437:21,733,314...21,824,303
Ensembl chrNW_004955437:21,731,584...21,816,324 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO RGD PMID:19318092 RGD:401901206 NCBI chrNW_004955431:583,165...646,991
Ensembl chrNW_004955431:580,713...647,345 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) UniProt PMID:28436939 NCBI chrNW_004955406:37,086,302...37,107,221
Ensembl chrNW_004955406:37,086,302...37,107,221 		JBrowse link
G Lacc1 laccase domain containing 1 involved_in ISO (PMID:28593945) UniProt PMID:28593945 NCBI chrNW_004955518:1,794,067...1,809,150
Ensembl chrNW_004955518:1,793,352...1,805,808 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:6391873|PMID:22733818) ARUK-UCL PMID:22733818 MGI:6391873 NCBI chrNW_004955452:9,335,481...9,358,177
Ensembl chrNW_004955452:9,334,587...9,358,444 		JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 involved_in ISO (MGI:5790524|PMID:27374331) CAFA PMID:27374331 MGI:5790524 NCBI chrNW_004955581:597,952...616,903
Ensembl chrNW_004955581:597,667...617,410 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 involved_in ISO (PMID:16260731) UniProt PMID:16260731 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (MGI:5803730|PMID:27288407) UniProt PMID:27288407 MGI:5803730 NCBI chrNW_004955467:10,547,706...10,578,355
Ensembl chrNW_004955467:10,547,294...10,578,387 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (MGI:3703830|PMID:17346996) UniProt PMID:17346996 MGI:3703830 NCBI chrNW_004955559:1,921,479...1,929,450
Ensembl chrNW_004955559:1,917,301...1,928,493 		JBrowse link
G Tek TEK receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:20060382) MGI PMID:20060382 NCBI chrNW_004955472:7,633,790...7,748,130
Ensembl chrNW_004955472:7,633,721...7,748,386 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 acts_upstream_of_or_within ISO (PMID:21236258) MGI PMID:21236258 NCBI chrNW_004955486:8,670,182...8,684,677 JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO (PMID:24882218) UniProt PMID:24882218 NCBI chrNW_004955414:21,495,593...21,513,703
Ensembl chrNW_004955414:21,481,129...21,514,548 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:18174455) UniProt PMID:18174455 NCBI chrNW_004955430:5,304,817...5,325,684
Ensembl chrNW_004955430:5,304,745...5,325,684 		JBrowse link
positive regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene, receptor tyrosine kinase involved_in ISO (MGI:3796803|PMID:18454155) UniProt PMID:18454155 MGI:3796803 NCBI chrNW_004955447:16,149,014...16,226,151
Ensembl chrNW_004955447:16,148,605...16,226,734 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 ISO RGD PMID:16818757 RGD:1600784 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G Plcg2 phospholipase C gamma 2 involved_in ISO (MGI:3844414|PMID:19136564) ARUK-UCL PMID:19136564 MGI:3844414 NCBI chrNW_004955522:4,352,890...4,480,735
Ensembl chrNW_004955522:4,358,233...4,468,986 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (MGI:5803730|PMID:27288407) UniProt PMID:27288407 MGI:5803730 NCBI chrNW_004955467:10,547,706...10,578,355
Ensembl chrNW_004955467:10,547,294...10,578,387 		JBrowse link
positive regulation of granzyme A production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:18832695) BHF-UCL PMID:18832695 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
positive regulation of granzyme B production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (PMID:11714776) UniProt PMID:11714776 NCBI chrNW_004955468:12,532,937...12,559,859
Ensembl chrNW_004955468:12,534,064...12,559,434 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (MGI:5562517|PMID:23871208) UniProt PMID:23871208 MGI:5562517 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:18832695) BHF-UCL PMID:18832695 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
positive regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase ISO RGD PMID:28352114 RGD:151665126 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120 		JBrowse link
G Cd37 CD37 molecule acts_upstream_of_or_within ISO (PMID:10891477) MGI PMID:10891477 NCBI chrNW_004955559:1,465,937...1,471,249
Ensembl chrNW_004955559:1,465,937...1,471,249 		JBrowse link
G Cd86 CD86 molecule involved_in ISO (MGI:5461234|PMID:23241883) UniProt PMID:23241883 MGI:5461234 NCBI chrNW_004955427:21,375,820...21,436,767
Ensembl chrNW_004955427:21,375,794...21,435,874 		JBrowse link
G Clcf1 cardiotrophin like cytokine factor 1 involved_in ISO (MGI:3777853|PMID:12023368) BHF-UCL PMID:12023368 MGI:3777853 NCBI chrNW_004955422:18,097,779...18,108,628
Ensembl chrNW_004955422:18,097,779...18,108,628 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 involved_in ISO (MGI:5644772|PMID:25222125) UniProt PMID:25222125 MGI:5644772 NCBI chrNW_004955410:12,814,993...12,820,852
Ensembl chrNW_004955410:12,814,479...12,822,777 		JBrowse link
G Ephb2 EPH receptor B2 involved_in ISO (PMID:24803541) ARUK-UCL PMID:24803541 NCBI chrNW_004955452:2,844,713...2,986,790
Ensembl chrNW_004955452:2,844,713...2,980,445 		JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:16819554) MGI PMID:16819554 NCBI chrNW_004955421:16,595,445...17,075,923
Ensembl chrNW_004955421:16,595,471...17,075,923 		JBrowse link
G Gpi glucose-6-phosphate isomerase involved_in ISO (PMID:3020690) CAFA PMID:3020690 NCBI chrNW_004955468:3,980,999...4,007,553
Ensembl chrNW_004955468:3,980,999...4,008,652 		JBrowse link
G Hpx hemopexin acts_upstream_of_or_within ISO (PMID:18641331) MGI PMID:18641331 NCBI chrNW_004955414:22,158,654...22,169,133
Ensembl chrNW_004955414:22,156,819...22,169,631 		JBrowse link
G Il10 interleukin 10 acts_upstream_of ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779 		JBrowse link
G Il13 interleukin 13 acts_upstream_of_or_within ISO IgE production after infection
(PMID:15944273)		 RGD
MGI		 PMID:11573960 PMID:15944273 RGD:633067 NCBI chrNW_004955408:4,046,406...4,049,795 JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 ISO IgE production after infection RGD PMID:11573960 RGD:633067 NCBI chrNW_004955534:1,157,758...1,205,158
Ensembl chrNW_004955534:1,160,340...1,204,911 		JBrowse link
G Il2 interleukin 2 acts_upstream_of
acts_upstream_of_or_within		 ISO (PMID:22962438)
(PMID:1830926)		 ARUK-UCL
MGI		 PMID:1830926 PMID:22962438 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265 		JBrowse link
G Il21 interleukin 21 involved_in ISO (MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:5450752 NCBI chrNW_004955428:18,057,096...18,065,492
Ensembl chrNW_004955428:18,057,096...18,065,492 		JBrowse link
G Il33 interleukin 33 involved_in ISO (MGI:3775141|PMID:18268038) BHF-UCL PMID:18268038 MGI:3775141 NCBI chrNW_004955434:10,145,449...10,187,595
Ensembl chrNW_004955434:10,171,812...10,188,948 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004955493:5,546,340...5,580,745
Ensembl chrNW_004955493:5,545,944...5,582,422 		JBrowse link
G Il5 interleukin 5 involved_in ISO (MGI:3775141|PMID:18268038) BHF-UCL PMID:18268038 MGI:3775141 NCBI chrNW_004955408:3,937,128...3,951,784
Ensembl chrNW_004955408:3,937,894...3,939,358 		JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:3491322)
(MGI:5450752|PMID:23045607)		 BHF-UCL
UniProt		 PMID:3491322 PMID:23045607 MGI:5450752 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Mzb1 marginal zone B and B1 cell specific protein involved_in ISO (MGI:4366098|PMID:19805154), (MGI:4421284|PMID:19805157) UniProt PMID:19805154 PMID:19805157 MGI:4366098 MGI:4421284 NCBI chrNW_004955418:1,170,365...1,172,581
Ensembl chrNW_004955418:1,170,365...1,172,581 		JBrowse link
G Phb1 prohibitin 1 involved_in ISO (MGI:5461234|PMID:23241883) UniProt PMID:23241883 MGI:5461234 NCBI chrNW_004955451:12,110,290...12,119,870
Ensembl chrNW_004955451:12,110,290...12,120,124 		JBrowse link
G Phb2 prohibitin 2 involved_in ISO (MGI:5461234|PMID:23241883) UniProt PMID:23241883 MGI:5461234 NCBI chrNW_004955413:4,557,969...4,563,697
Ensembl chrNW_004955413:4,558,259...4,563,582 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO (PMID:1793833) UniProt PMID:1793833 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Rbp4 retinol binding protein 4 involved_in ISO (MGI:3796317|PMID:10944490) BHF-UCL PMID:10944490 MGI:3796317 NCBI chrNW_004955507:112,342...120,050
Ensembl chrNW_004955507:108,669...120,584 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within ISO (PMID:16227612) MGI PMID:16227612 NCBI chrNW_004955473:5,224,635...5,237,066
Ensembl chrNW_004955473:5,222,408...5,237,260 		JBrowse link
G Tlr9 toll like receptor 9 involved_in ISO (PMID:23857366) UniProt PMID:23857366 NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582 		JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (MGI:74350|PMID:7749983) BHF-UCL PMID:7749983 MGI:74350 NCBI chrNW_004955486:9,565,424...9,569,836
Ensembl chrNW_004955486:9,567,220...9,569,676 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:74350|PMID:7749983) BHF-UCL PMID:7749983 MGI:74350 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
G Vamp3 vesicle associated membrane protein 3 NOT|involved_in ISO (PMID:24055037) UniProt PMID:24055037 NCBI chrNW_004955486:5,103,228...5,112,157
Ensembl chrNW_004955486:5,103,106...5,112,176 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:11460154)
(MGI:5605956|PMID:12612580)		 UniProt PMID:11460154 PMID:12612580 MGI:5605956 NCBI chrNW_004955455:3,037,885...3,041,827 JBrowse link
positive regulation of immunoglobulin production in mucosal tissue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CUNH17orf99 chromosome unknown C17orf99 homolog involved_in ISO (MGI:6103709|PMID:28978694) UniProt PMID:28978694 MGI:6103709 NCBI chrNW_004955506:4,397,221...4,408,645 JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (MGI:5009207|PMID:9973465) BHF-UCL PMID:9973465 MGI:5009207 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) BHF-UCL PMID:12496423 MGI:3763508 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 acts_upstream_of_or_within ISO (PMID:21255825) MGI PMID:21255825 NCBI chrNW_004955419:28,683,896...28,692,006
Ensembl chrNW_004955419:28,683,896...28,693,395 		JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within ISO (PMID:21255825) MGI PMID:21255825 NCBI chrNW_004955484:3,088,133...3,089,551
Ensembl chrNW_004955484:3,088,624...3,089,472 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISO (MGI:6393148|PMID:31806351) UniProt PMID:31806351 MGI:6393148 NCBI chrNW_004955429:13,616,647...13,638,657
Ensembl chrNW_004955429:13,616,647...13,661,389 		JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISO (MGI:6370097|PMID:28114273) UniProt PMID:28114273 MGI:6370097 NCBI chrNW_004955422:17,626,606...17,684,890
Ensembl chrNW_004955422:17,647,530...17,682,132 		JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISO (MGI:6370097|PMID:28114273) UniProt PMID:28114273 MGI:6370097 NCBI chrNW_004955567:895,334...901,240
Ensembl chrNW_004955567:894,608...900,578 		JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chrNW_004955486:2,191,903...2,197,193
Ensembl chrNW_004955486:2,191,903...2,198,538 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:4821506|PMID:20671152) UniProt PMID:20671152 MGI:4821506 NCBI chrNW_004955491:8,177,422...8,219,764
Ensembl chrNW_004955491:8,177,422...8,219,766 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (MGI:5468036|PMID:23306439), (MGI:5476381|PMID:23333305), (MGI:5490831|PMID:23333306) UniProt PMID:23306439 PMID:23333305 PMID:23333306 MGI:5468036 MGI:5476381 MGI:5490831 NCBI chrNW_004955440:16,977,710...17,047,809
Ensembl chrNW_004955440:16,979,042...17,041,748 		JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chrNW_004955415:16,180,074...16,282,937
Ensembl chrNW_004955415:16,180,051...16,280,864 		JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chrNW_004955510:6,021,477...6,114,745
Ensembl chrNW_004955510:6,075,510...6,114,898 		JBrowse link
G Tfrc transferrin receptor involved_in ISO (PMID:26642240) UniProt PMID:26642240 NCBI chrNW_004955420:12,348,392...12,372,714
Ensembl chrNW_004955420:12,348,821...12,372,691 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23760478)
(MGI:3041657|PMID:15077110), (MGI:3046005|PMID:15159415)
(PMID:23345425)		 UniProt PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 MGI:3041657 MGI:3046005 NCBI chrNW_004955416:9,962,736...10,035,433
Ensembl chrNW_004955416:9,962,897...10,035,278 		JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Msh2 mutS homolog 2 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (PMID:23241889) MGI PMID:23241889 NCBI chrNW_004955514:1,084,522...1,162,624
Ensembl chrNW_004955514:1,069,085...1,162,624 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004955460:13,762,854...13,791,462 JBrowse link
G Tgfb1 transforming growth factor beta 1 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441 		JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin like cytokine factor 1 involved_in ISO (MGI:3777853|PMID:12023368) BHF-UCL PMID:12023368 MGI:3777853 NCBI chrNW_004955422:18,097,779...18,108,628
Ensembl chrNW_004955422:18,097,779...18,108,628 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004955458:4,833,417...4,847,956
Ensembl chrNW_004955458:4,833,515...4,843,273 		JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 acts_upstream_of_or_within ISO (PMID:25404367) MGI PMID:25404367 NCBI chrNW_004955481:6,986,128...7,031,113
Ensembl chrNW_004955481:6,986,502...7,030,742 		JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within ISO (PMID:7688139) MGI PMID:7688139 NCBI chrNW_004955457:11,159,769...11,253,099
Ensembl chrNW_004955457:11,162,282...11,192,991 		JBrowse link
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:1830926) MGI PMID:1830926 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12882831), (PMID:14988498) MGI PMID:12882831 PMID:14988498 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Mlh1 mutL homolog 1 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Msh2 mutS homolog 2 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
G Pagr1 PAXIP1 associated glutamate rich protein 1 involved_in ISO (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 NCBI chrNW_004955493:7,142,048...7,144,836
Ensembl chrNW_004955493:7,142,272...7,144,389 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 NCBI chrNW_004955491:8,177,422...8,219,764
Ensembl chrNW_004955491:8,177,422...8,219,766 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004955460:13,762,854...13,791,462 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:9015183) MGI PMID:9015183 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004955451:13,315,237...13,317,888
Ensembl chrNW_004955451:13,315,859...13,325,937 		JBrowse link
positive regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card9 caspase recruitment domain family member 9 acts_upstream_of_or_within ISO (PMID:17187069) MGI PMID:17187069 NCBI chrNW_004955513:4,350,873...4,359,345
Ensembl chrNW_004955513:4,350,147...4,359,345 		JBrowse link
G Cd36 CD36 molecule (CD36 blood group) acts_upstream_of_or_within ISO (PMID:16061696)
(PMID:15690042)		 MGI PMID:15690042 PMID:16061696 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313 		JBrowse link
G Cd74 CD74 molecule involved_in ISO (MGI:4943655|PMID:19413900) BHF-UCL PMID:19413900 MGI:4943655 NCBI chrNW_004955415:4,129,151...4,138,336
Ensembl chrNW_004955415:4,129,254...4,137,826 		JBrowse link
G Gprc5b G protein-coupled receptor class C group 5 member B involved_in ISO (MGI:5545939|PMID:23169819) UniProt PMID:23169819 MGI:5545939 NCBI chrNW_004955442:3,548,478...3,571,341
Ensembl chrNW_004955442:3,548,478...3,571,341 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:9348310) MGI PMID:9348310 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:6391873|PMID:22733818) ARUK-UCL PMID:22733818 MGI:6391873 NCBI chrNW_004955452:9,335,481...9,358,177
Ensembl chrNW_004955452:9,334,587...9,358,444 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 acts_upstream_of_or_within ISO (PMID:24020373) MGI PMID:24020373 NCBI chrNW_004955406:42,231,858...42,276,477
Ensembl chrNW_004955406:42,231,858...42,276,477 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor acts_upstream_of_or_within ISO (PMID:10607756), (PMID:11067888), (PMID:12872135)
(PMID:12872135)		 MGI PMID:10607756 PMID:11067888 PMID:12872135 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004955410:31,681,191...31,725,173
Ensembl chrNW_004955410:31,681,077...31,725,173 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:14560001), (PMID:15220916)
(PMID:15220916), (PMID:18261938)
(PMID:15692051), (PMID:18261938)
(PMID:18261938)		 MGI PMID:14560001 PMID:15220916 PMID:15692051 PMID:18261938 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:18490713)
(PMID:11016935)		 MGI PMID:11016935 PMID:18490713 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926 		JBrowse link
G Panx1 pannexin 1 acts_upstream_of_or_within ISO (PMID:18490713) MGI PMID:18490713 NCBI chrNW_004955414:405,483...448,470
Ensembl chrNW_004955414:401,188...448,470 		JBrowse link
G Plcg2 phospholipase C gamma 2 acts_upstream_of ISO (MGI:5300086|PMID:22041900) ARUK-UCL PMID:22041900 MGI:5300086 NCBI chrNW_004955522:4,352,890...4,480,735
Ensembl chrNW_004955522:4,358,233...4,468,986 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (PMID:11894098), (PMID:18261938) MGI PMID:11894098 PMID:18261938 NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228 		JBrowse link
G Rtn4 reticulon 4 involved_in ISO (MGI:4366092|PMID:19805174) UniProt PMID:19805174 MGI:4366092 NCBI chrNW_004955424:28,061,346...28,125,838 JBrowse link
G Sema7a semaphorin 7A (JohnMiltonHagen blood group) involved_in ISO (MGI:3710037|PMID:17377534) UniProt PMID:17377534 MGI:3710037 NCBI chrNW_004955450:3,401,732...3,424,547
Ensembl chrNW_004955450:3,401,777...3,423,363 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:5319292|PMID:22315447) UniProt PMID:22315447 MGI:5319292 NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663 		JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within ISO (PMID:14691481) MGI PMID:14691481 NCBI chrNW_004955514:598,840...603,390
Ensembl chrNW_004955514:596,829...604,051 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 acts_upstream_of_or_within ISO (PMID:12855817)
(PMID:12872135)		 MGI PMID:12855817 PMID:12872135 NCBI chrNW_004955495:4,197,083...4,204,999
Ensembl chrNW_004955495:4,202,372...4,204,513 		JBrowse link
G Tirap TIR domain containing adaptor protein acts_upstream_of_or_within ISO (PMID:15690042) MGI PMID:15690042 NCBI chrNW_004955412:27,303,548...27,315,031
Ensembl chrNW_004955412:27,312,489...27,315,031 		JBrowse link
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:18261938)
(PMID:15690042)
(PMID:10549626), (PMID:11067888)		 MGI PMID:10549626 PMID:11067888 PMID:15690042 PMID:18261938 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258 		JBrowse link
G Tlr3 toll like receptor 3 acts_upstream_of_or_within ISO (PMID:18261938)
(PMID:12855817)		 MGI PMID:12855817 PMID:18261938 NCBI chrNW_004955403:22,977,882...23,001,392
Ensembl chrNW_004955403:22,979,120...23,001,467 		JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of_or_within ISO (PMID:10623794)
(PMID:10549626), (PMID:10607756), (PMID:15661922)
(PMID:18261938), (PMID:21609717)
(PMID:14691481)		 MGI PMID:10549626 PMID:10607756 PMID:10623794 PMID:14691481 PMID:15661922 More... NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tlr7 toll like receptor 7 acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004955544:424,897...443,562
Ensembl chrNW_004955544:424,850...443,564 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:18174455) UniProt PMID:18174455 NCBI chrNW_004955430:5,304,817...5,325,684
Ensembl chrNW_004955430:5,304,745...5,325,684 		JBrowse link
positive regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1a Fc fragment of IgE receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) MGI PMID:9000133 NCBI chrNW_004955468:11,094,792...11,101,191
Ensembl chrNW_004955468:11,094,788...11,101,173 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:14764707) MGI PMID:14764707 NCBI chrNW_004955468:12,971,931...12,975,206
Ensembl chrNW_004955468:12,971,931...12,975,206 		JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase involved_in ISO (PMID:20100931) UniProt PMID:20100931 NCBI chrNW_004955447:16,149,014...16,226,151
Ensembl chrNW_004955447:16,148,605...16,226,734 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4 group A member 3 involved_in ISO (MGI:5586645|PMID:24586680) UniProt PMID:24586680 MGI:5586645 NCBI chrNW_004955419:25,779,368...25,817,445
Ensembl chrNW_004955419:25,779,178...25,818,706 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within ISO (PMID:9000133) MGI PMID:9000133 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581 		JBrowse link
positive regulation of myeloid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk4 calcium/calmodulin dependent protein kinase IV NOT|involved_in ISO (PMID:17909078) UniProt PMID:17909078 NCBI chrNW_004955418:3,664,352...3,887,175
Ensembl chrNW_004955418:3,664,479...3,887,175 		JBrowse link
G Ddx1 DEAD-box helicase 1 involved_in ISO (MGI:5050760|PMID:21703541) UniProt PMID:21703541 MGI:5050760 NCBI chrNW_004955487:9,085,950...9,117,599
Ensembl chrNW_004955487:9,085,918...9,119,979 		JBrowse link
G Ddx21 DExD-box helicase 21 involved_in ISO (MGI:5050760|PMID:21703541) UniProt PMID:21703541 MGI:5050760 NCBI chrNW_004955437:22,050,029...22,071,213
Ensembl chrNW_004955437:22,050,937...22,071,118 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (MGI:5050760|PMID:21703541) UniProt PMID:21703541 MGI:5050760 NCBI chrNW_004955448:5,634,072...5,676,272
Ensembl chrNW_004955448:5,634,072...5,676,319 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (MGI:5050760|PMID:21703541) UniProt PMID:21703541 MGI:5050760 NCBI chrNW_004955415:14,691,918...14,704,782
Ensembl chrNW_004955415:14,695,438...14,703,672 		JBrowse link
G Rigi RNA sensor RIG-I involved_in ISO (MGI:5050760|PMID:21703541) UniProt PMID:21703541 MGI:5050760 NCBI chrNW_004955472:3,093,895...3,135,524
Ensembl chrNW_004955472:3,093,939...3,133,987 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 involved_in ISO (MGI:5050760|PMID:21703541) UniProt PMID:21703541 MGI:5050760 NCBI chrNW_004955495:4,197,083...4,204,999
Ensembl chrNW_004955495:4,202,372...4,204,513 		JBrowse link
positive regulation of myeloid leukocyte cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mif macrophage migration inhibitory factor involved_in ISO (MGI:2156302|PMID:11756671) BHF-UCL PMID:11756671 MGI:2156302 NCBI chrNW_004955455:8,367,566...8,368,460
Ensembl chrNW_004955455:8,367,566...8,368,460 		JBrowse link
positive regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd160 CD160 molecule involved_in ISO (PMID:17307798) UniProt PMID:17307798 NCBI chrNW_004955568:365,700...372,149 JBrowse link
G Cd226 CD226 molecule acts_upstream_of_or_within ISO (PMID:24658051) MGI PMID:24658051 NCBI chrNW_004955402:53,408,861...53,560,896
Ensembl chrNW_004955402:53,473,131...53,560,924 		JBrowse link
G Clnk cytokine dependent hematopoietic cell linker involved_in ISO (MGI:3774350|PMID:16439675) UniProt PMID:16439675 MGI:3774350 NCBI chrNW_004955549:2,166,891...2,375,902 JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (PMID:14764669) MGI PMID:14764669 NCBI chrNW_004955428:18,057,096...18,065,492
Ensembl chrNW_004955428:18,057,096...18,065,492 		JBrowse link
positive regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2-microglobulin involved_in ISO (PMID:24643698) BHF-UCL PMID:24643698 NCBI chrNW_004955416:11,205,503...11,211,325
Ensembl chrNW_004955416:11,204,849...11,215,568 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) UniProt PMID:16818763 NCBI chrNW_004955406:42,773,368...42,796,205 JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO (PMID:16601243) CACAO PMID:16601243 NCBI chrNW_004955457:7,282,403...7,288,918
Ensembl chrNW_004955457:7,282,403...7,288,918 		JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004955402:42,919,480...42,968,873
Ensembl chrNW_004955402:42,911,649...42,972,429 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004955411:17,177,335...17,229,957
Ensembl chrNW_004955411:17,177,335...17,229,957 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within ISO (PMID:16227612) MGI PMID:16227612 NCBI chrNW_004955473:5,224,635...5,237,066
Ensembl chrNW_004955473:5,222,408...5,237,260 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4942267|PMID:9670042), (MGI:4943387|PMID:18354165) BHF-UCL PMID:9670042 PMID:18354165 MGI:4942267 MGI:4943387 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
G Traf2 TNF receptor associated factor 2 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004955513:4,964,692...4,984,359
Ensembl chrNW_004955513:4,967,984...4,983,987 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004955422:9,925,765...9,950,354
Ensembl chrNW_004955422:9,932,680...9,949,100 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (MGI:85636|PMID:9029087) BHF-UCL PMID:9029087 MGI:85636 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
positive regulation of T-helper 1 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT-rich interaction domain 5A involved_in ISO (MGI:5887181|PMID:27671645) UniProt PMID:27671645 MGI:5887181 NCBI chrNW_004955470:3,951,010...3,964,391
Ensembl chrNW_004955470:3,950,750...3,965,750 		JBrowse link
G Il18 interleukin 18 involved_in ISO (PMID:10653850) UniProt PMID:10653850 NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634 		JBrowse link
G Il18r1 interleukin 18 receptor 1 involved_in ISO (PMID:10653850) UniProt PMID:10653850 NCBI chrNW_004955470:7,854,995...7,887,810
Ensembl chrNW_004955470:7,854,988...7,887,883 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:10653850) UniProt PMID:10653850 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 involved_in ISO (PMID:10653850) UniProt PMID:10653850 NCBI chrNW_004955470:7,685,498...7,703,374 JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (MGI:5700493|PMID:9126961) UniProt PMID:9126961 MGI:5700493 NCBI chrNW_004955468:12,336,744...12,383,917
Ensembl chrNW_004955468:12,334,307...12,370,334 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:1354779|PMID:10761931) UniProt PMID:10761931 MGI:1354779 NCBI chrNW_004955451:13,315,237...13,317,888
Ensembl chrNW_004955451:13,315,859...13,325,937 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (MGI:5009207|PMID:9973465) BHF-UCL PMID:9973465 MGI:5009207 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
positive regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 CD81 molecule involved_in ISO (PMID:8766544)
(MGI:1926561|PMID:11046035)		 UniProt PMID:8766544 PMID:11046035 MGI:1926561 NCBI chrNW_004955422:14,155,682...14,175,181
Ensembl chrNW_004955422:14,155,682...14,175,181 		JBrowse link
G Dennd1b DENN domain containing 1B involved_in ISO (PMID:26774822)
(MGI:5751612|PMID:26774822)		 UniProt PMID:26774822 MGI:5751612 NCBI chrNW_004955406:34,021,508...34,241,735
Ensembl chrNW_004955406:34,027,046...34,241,737 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (PMID:15087456) MGI PMID:15087456 NCBI chrNW_004955421:24,448,446...24,477,885
Ensembl chrNW_004955421:24,457,496...24,478,744 		JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:20554961) UniProt PMID:20554961 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:5795829|PMID:11159963) BHF-UCL PMID:11159963 MGI:5795829 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) UniProt PMID:26098997 MGI:5689221 NCBI chrNW_004955581:597,952...616,903
Ensembl chrNW_004955581:597,667...617,410 		JBrowse link
G Prkcz protein kinase C zeta involved_in ISO (MGI:3584076|PMID:15987782) UniProt PMID:15987782 MGI:3584076 NCBI chrNW_004955486:8,947,579...9,021,702
Ensembl chrNW_004955486:8,947,579...9,021,702 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISO (MGI:3844206|PMID:19047684) UniProt PMID:19047684 MGI:3844206 NCBI chrNW_004955487:1,988,226...2,001,731
Ensembl chrNW_004955487:1,987,405...2,001,731 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (MGI:5009207|PMID:9973465) BHF-UCL PMID:9973465 MGI:5009207 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Evpl envoplakin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955506:6,227,488...6,246,339
Ensembl chrNW_004955506:6,227,673...6,246,138 		JBrowse link
G Ivl involucrin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955592:522,730...525,728 JBrowse link
G Ppl periplakin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955442:12,581,918...12,627,407
Ensembl chrNW_004955442:12,581,879...12,626,516 		JBrowse link
regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 acts_upstream_of_or_within ISO (PMID:22710871) MGI PMID:22710871 NCBI chrNW_004955411:31,501,191...31,646,407
Ensembl chrNW_004955411:31,522,420...31,646,827 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO (MGI:5888814|PMID:28052249) ARUK-UCL PMID:28052249 MGI:5888814 NCBI chrNW_004955486:1,790,531...1,817,986
Ensembl chrNW_004955486:1,792,115...1,818,362 		JBrowse link
G Tril TLR4 interactor with leucine rich repeats involved_in ISO (PMID:19710467) UniProt PMID:19710467 NCBI chrNW_004955410:30,497,953...30,503,444
Ensembl chrNW_004955410:30,500,276...30,502,735 		JBrowse link
regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:19047410) MGI PMID:19047410 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258 		JBrowse link
G Tlr3 toll like receptor 3 acts_upstream_of_or_within ISO (PMID:19047410) MGI PMID:19047410 NCBI chrNW_004955403:22,977,882...23,001,392
Ensembl chrNW_004955403:22,979,120...23,001,467 		JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of_or_within ISO (PMID:19047410) MGI PMID:19047410 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tlr9 toll like receptor 9 acts_upstream_of_or_within ISO (PMID:19047410) MGI PMID:19047410 NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582 		JBrowse link
regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (PMID:12958312) MGI PMID:12958312 NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093 		JBrowse link
G Cd40lg CD40 ligand acts_upstream_of_or_within ISO (PMID:12958312) MGI PMID:12958312 NCBI chrNW_004955489:8,465,571...8,477,714
Ensembl chrNW_004955489:8,465,164...8,477,746 		JBrowse link
G Cgas cyclic GMP-AMP synthase acts_upstream_of_or_within ISO (PMID:26371324) MGI PMID:26371324 NCBI chrNW_004955493:8,593,104...8,607,297 JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:16275384) MGI PMID:16275384 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Pkn1 protein kinase N1 acts_upstream_of_or_within ISO (PMID:23223530) MGI PMID:23223530 NCBI chrNW_004955415:33,040,868...33,062,753
Ensembl chrNW_004955415:33,043,918...33,063,567 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:12958312) MGI PMID:12958312 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
G Traf2 TNF receptor associated factor 2 acts_upstream_of_or_within ISO (PMID:12958312) MGI PMID:12958312 NCBI chrNW_004955513:4,964,692...4,984,359
Ensembl chrNW_004955513:4,967,984...4,983,987 		JBrowse link
G Traf6 TNF receptor associated factor 6 acts_upstream_of_or_within ISO (PMID:12958312) MGI PMID:12958312 NCBI chrNW_004955422:9,925,765...9,950,354
Ensembl chrNW_004955422:9,932,680...9,949,100 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (PMID:26320659)
(PMID:26371324)		 MGI PMID:26320659 PMID:26371324 NCBI chrNW_004955532:533,877...535,767
Ensembl chrNW_004955532:533,877...535,767 		JBrowse link
regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor acts_upstream_of_or_within ISO (PMID:21211721) MGI PMID:21211721 NCBI chrNW_004955424:16,338,546...16,449,074
Ensembl chrNW_004955424:16,336,228...16,448,766 		JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor involved_in ISO (MGI:5004983|PMID:21518874) UniProt PMID:21518874 MGI:5004983 NCBI chrNW_004955481:4,462,270...4,497,364
Ensembl chrNW_004955481:4,462,270...4,497,364 		JBrowse link
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:16275384) MGI PMID:16275384 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:11057672) MGI PMID:11057672 NCBI chrNW_004955415:32,749,682...32,762,532
Ensembl chrNW_004955415:32,749,094...32,761,882 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (PMID:17137798) MGI PMID:17137798 NCBI chrNW_004955415:11,643,846...11,666,131
Ensembl chrNW_004955415:11,643,846...11,666,131 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (MGI:5649169|PMID:25310967) UniProt PMID:25310967 MGI:5649169 NCBI chrNW_004955482:2,327,137...2,343,980 JBrowse link
regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Litaf lipopolysaccharide induced TNF factor acts_upstream_of_or_within ISO (PMID:16954198) MGI PMID:16954198 NCBI chrNW_004955442:7,054,418...7,084,973
Ensembl chrNW_004955442:7,077,823...7,083,437 		JBrowse link
G Ube2j1 ubiquitin conjugating enzyme E2 J1 acts_upstream_of_or_within ISO (PMID:24020373) MGI PMID:24020373 NCBI chrNW_004955411:16,076,647...16,091,554
Ensembl chrNW_004955411:16,074,551...16,091,570 		JBrowse link
regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chrNW_004955453:6,846,625...6,850,007
Ensembl chrNW_004955453:6,846,549...6,850,031 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 involved_in ISO (MGI:5926947|PMID:28507030) UniProt PMID:28507030 MGI:5926947 NCBI chrNW_004955420:25,641,184...25,664,413 JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO (MGI:5888814|PMID:28052249) ARUK-UCL PMID:28052249 MGI:5888814 NCBI chrNW_004955486:1,790,531...1,817,986
Ensembl chrNW_004955486:1,792,115...1,818,362 		JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 involved_in ISO (PMID:20656926) UniProt PMID:20656926 NCBI chrNW_004955559:1,539,036...1,581,800
Ensembl chrNW_004955559:1,546,365...1,581,712 		JBrowse link
somatic diversification of immunoglobulins term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnbl1 catenin beta like 1 involved_in ISO (PMID:18722174) UniProt PMID:18722174 NCBI chrNW_004955445:18,809,389...18,975,858
Ensembl chrNW_004955445:18,809,023...18,976,255 		JBrowse link
G Polb DNA polymerase beta acts_upstream_of_or_within ISO (PMID:24388753) MGI PMID:24388753 NCBI chrNW_004955536:542,179...595,198
Ensembl chrNW_004955536:540,836...595,198 		JBrowse link
somatic hypermutation of immunoglobulin genes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exo1 exonuclease 1 acts_upstream_of_or_within ISO (PMID:14716311) MGI PMID:14716311 NCBI chrNW_004955406:10,248,981...10,276,207
Ensembl chrNW_004955406:10,245,886...10,275,522 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISO (PMID:35450882)
(MGI:7279208|PMID:35450882)		 UniProt PMID:35450882 MGI:7279208 NCBI chrNW_004955429:13,616,647...13,638,657
Ensembl chrNW_004955429:13,616,647...13,661,389 		JBrowse link
G Mcm3ap minichromosome maintenance complex component 3 associated protein involved_in ISO (PMID:23652018) UniProt PMID:23652018 NCBI chrNW_004955407:42,657,422...42,706,339
Ensembl chrNW_004955407:42,657,588...42,705,315 		JBrowse link
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:10092760), (PMID:10429667) MGI PMID:10092760 PMID:10429667 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within
NOT|acts_upstream_of_or_within		 ISO (PMID:14568978)
(PMID:9607916)
(PMID:9607915)
(PMID:15494304)
(PMID:9697842), (PMID:9697843)		 MGI PMID:9607915 PMID:9607916 PMID:9697842 PMID:9697843 PMID:14568978 More... NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
G Msh3 mutS homolog 3 NOT|acts_upstream_of_or_within ISO (PMID:10662804) MGI PMID:10662804 NCBI chrNW_004955418:29,149,595...29,274,067
Ensembl chrNW_004955418:29,150,085...29,274,437 		JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO (PMID:16618598)
(PMID:10662804), (PMID:15238604), (PMID:17015724)		 MGI PMID:10662804 PMID:15238604 PMID:16618598 PMID:17015724 NCBI chrNW_004955441:14,451,207...14,471,316
Ensembl chrNW_004955441:14,451,307...14,471,227 		JBrowse link
G Nuggc nuclear GTPase, germinal center associated acts_upstream_of_or_within ISO (PMID:22833677) MGI PMID:22833677 NCBI chrNW_004955403:50,507,971...50,558,881
Ensembl chrNW_004955403:50,507,116...50,558,826 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in
acts_upstream_of_or_within		 ISO (MGI:1261707|PMID:9618520)
(PMID:10429667)		 CAFA
MGI		 PMID:9618520 PMID:10429667 MGI:1261707 NCBI chrNW_004955460:13,762,854...13,791,462 JBrowse link
G Polb DNA polymerase beta acts_upstream_of_or_within ISO (PMID:24388753) MGI PMID:24388753 NCBI chrNW_004955536:542,179...595,198
Ensembl chrNW_004955536:540,836...595,198 		JBrowse link
G Polm DNA polymerase mu acts_upstream_of_or_within ISO (PMID:15789338) MGI PMID:15789338 NCBI chrNW_004955456:7,886,182...7,893,800
Ensembl chrNW_004955456:7,886,291...7,895,085 		JBrowse link
G Polq DNA polymerase theta involved_in ISO (MGI:3603978|PMID:16172387), (MGI:3609287|PMID:16222339), (MGI:3692678|PMID:16890500) UniProt PMID:16172387 PMID:16222339 PMID:16890500 MGI:3603978 MGI:3609287 MGI:3692678 NCBI chrNW_004955427:20,779,332...20,895,094
Ensembl chrNW_004955427:20,778,952...20,894,989 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (MGI:6157199|PMID:29669924) UniProt PMID:29669924 MGI:6157199 NCBI chrNW_004955422:24,714,103...24,780,672
Ensembl chrNW_004955422:24,735,161...24,778,830 		JBrowse link
G Ung uracil DNA glycosylase acts_upstream_of_or_within ISO (PMID:17015724)
(PMID:15494304)		 MGI PMID:15494304 PMID:17015724 NCBI chrNW_004955455:10,266,989...10,282,196
Ensembl chrNW_004955455:10,266,989...10,282,196 		JBrowse link
somatic recombination of immunoglobulin gene segments term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:11828012) MGI PMID:11828012 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within ISO (PMID:14568978)
(PMID:11828012)
(PMID:15494304)
(PMID:14563316), (PMID:15955838)		 MGI PMID:11828012 PMID:14563316 PMID:14568978 PMID:15494304 PMID:15955838 NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
G Msh3 mutS homolog 3 acts_upstream_of_or_within ISO (PMID:15238604) MGI PMID:15238604 NCBI chrNW_004955418:29,149,595...29,274,067
Ensembl chrNW_004955418:29,150,085...29,274,437 		JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO (PMID:15238604) MGI PMID:15238604 NCBI chrNW_004955441:14,451,207...14,471,316
Ensembl chrNW_004955441:14,451,307...14,471,227 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component acts_upstream_of_or_within ISO (PMID:11828012) MGI PMID:11828012 NCBI chrNW_004955460:13,762,854...13,791,462 JBrowse link
G Ung uracil DNA glycosylase acts_upstream_of_or_within ISO (PMID:15494304) MGI PMID:15494304 NCBI chrNW_004955455:10,266,989...10,282,196
Ensembl chrNW_004955455:10,266,989...10,282,196 		JBrowse link
somatic recombination of immunoglobulin genes involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:12743174) MGI PMID:12743174 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within ISO (PMID:12743174) MGI PMID:12743174 NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    immune system process 1980
      production of molecular mediator of immune response 215
        antimicrobial peptide production + 12
        cytokine production involved in immune response + 114
        granulysin production 0
        granzyme A production + 1
        granzyme B production + 3
        immunoglobulin production + 105
        negative regulation of production of molecular mediator of immune response + 42
        perforin production 0
        positive regulation of production of molecular mediator of immune response + 132
        regulation of production of molecular mediator of immune response + 186
Path 2
Term Annotations click to browse term
  biological_process 12346
    metabolic process 7467
      cellular metabolic process 6295
        cellular biosynthetic process 5017
          macromolecule biosynthetic process 4614
            gene expression 4278
              production of molecular mediator of immune response 215
                antimicrobial peptide production + 12
                cytokine production involved in immune response + 114
                granulysin production 0
                granzyme A production + 1
                granzyme B production + 3
                immunoglobulin production + 105
                negative regulation of production of molecular mediator of immune response + 42
                perforin production 0
                positive regulation of production of molecular mediator of immune response + 132
                regulation of production of molecular mediator of immune response + 186
paths to the root