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ONTOLOGY REPORT - ANNOTATIONS

Term:granuloma formation
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Accession:GO:0002432 term browser browse the term
Definition:The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.


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granuloma formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEBPB CCAAT enhancer binding protein beta involved_in ISS UniProt GO_REF:0000024 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668 		JBrowse link
G UNC13D unc-13 homolog D involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17420270) Ensembl
MGI		 PMID:17420270 GO_REF:0000107 NCBI chr17:75,827,225...75,844,404
Ensembl chr17:75,827,225...75,844,785 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    immune system process 3226
      immune effector process 824
        granuloma formation 2
          negative regulation of granuloma formation 0
          positive regulation of granuloma formation 0
          regulation of granuloma formation + 0
Path 2
Term Annotations click to browse term
  biological_process 19669
    response to stimulus 10176
      response to stress 4593
        defense response 2110
          inflammatory response 1025
            chronic inflammatory response 33
              granuloma formation 2
                negative regulation of granuloma formation 0
                positive regulation of granuloma formation 0
                regulation of granuloma formation + 0
paths to the root