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ONTOLOGY REPORT - ANNOTATIONS


Term:granuloma formation
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Accession:GO:0002432 term browser browse the term
Definition:The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.



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granuloma formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cebpb CCAAT/enhancer binding protein beta involved_in ISS
ISO
GO_REF:0000024
(MGI:4360613|PMID:17911624)
UniProt
RGD
PMID:17911624 GO_REF:0000024 MGI:4360613 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Unc13d unc-13 homolog D involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3628822 (MGI:3703574|PMID:17420270)
Ensembl
RGD
PMID:17420270 GO_REF:0000107 MGI:3703574 NCBI chr10:101,296,755...101,311,513
Ensembl chr10:101,296,776...101,311,687
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    immune system process 2829
      immune effector process 724
        granuloma formation 2
          negative regulation of granuloma formation 0
          positive regulation of granuloma formation 0
          regulation of granuloma formation + 0
Path 2
Term Annotations click to browse term
  biological_process 19497
    response to stimulus 10416
      response to stress 4097
        defense response 1701
          inflammatory response 759
            chronic inflammatory response 33
              granuloma formation 2
                negative regulation of granuloma formation 0
                positive regulation of granuloma formation 0
                regulation of granuloma formation + 0
paths to the root