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ONTOLOGY REPORT - ANNOTATIONS


Term:Fc receptor mediated stimulatory signaling pathway
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Accession:GO:0002431 term browser browse the term
Definition:A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
Synonyms:exact_synonym: Fc receptor mediated stimulatory signalling pathway



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Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blk B lymphoid kinase involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr14:63,372,837...63,417,187
Ensembl chr14:63,372,836...63,417,037
JBrowse link
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:3029067|PMID:14764707)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:14764707 PMID:21873635 MGI:3029067 MGI:6201960 NCBI chr 1:171,229,572...171,234,349
Ensembl chr 1:171,229,572...171,234,365
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in IMP
IBA
(MGI:3703139|PMID:16272347)
(MGI:6201960|PMID:21873635)
UniProt
GO_Central
PMID:16272347 PMID:21873635 MGI:3703139 MGI:6201960 NCBI chr 4:3,678,068...3,791,612
Ensembl chr 4:3,678,115...3,813,122
JBrowse link
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2b Fc receptor, IgG, low affinity IIb involved_in ISO (PMID:2142460) ARUK-UCL PMID:2142460 NCBI chr 1:170,960,558...170,976,071
Ensembl chr 1:170,958,617...170,976,547
JBrowse link
G Myo1g myosin IG involved_in IMP (MGI:5586792|PMID:23038771) UniProt PMID:23038771 MGI:5586792 NCBI chr11:6,506,548...6,520,960
Ensembl chr11:6,506,548...6,520,965
JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 involved_in IMP (MGI:6271154|PMID:25568335) UniProt PMID:25568335 MGI:6271154 NCBI chr14:26,918,986...26,970,611
Ensembl chr14:26,918,988...26,971,232
JBrowse link
G Cd47 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr16:49,851,328...49,912,503
Ensembl chr16:49,800,533...49,915,010
JBrowse link
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 antigen involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr18:89,176,954...89,272,232
Ensembl chr18:89,176,967...89,272,229
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO RGD
MGI
PMID:16177098 GO_REF:0000096 MGI:4417868 RGD:1578516 NCBI chr 4:3,678,068...3,791,612
Ensembl chr 4:3,678,115...3,813,122
JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 involved_in IMP (MGI:6271154|PMID:25568335) UniProt PMID:25568335 MGI:6271154 NCBI chr10:83,600,033...83,648,877
Ensembl chr10:83,600,033...83,648,738
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in IGI (MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:3774343 NCBI chr 1:138,062,859...138,175,756
Ensembl chr 1:138,062,861...138,175,708
JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in IGI (MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:3774343 NCBI chr 2:90,429,756...90,580,694
Ensembl chr 2:90,429,754...90,580,647
JBrowse link
G Rap1a RAS-related protein 1a involved_in ISO RGD
MGI
PMID:18832707 GO_REF:0000096 MGI:4417868 RGD:9835043 NCBI chr 3:105,727,260...105,801,394
Ensembl chr 3:105,727,267...105,801,336
JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor (GEF) 1 involved_in ISO RGD
MGI
PMID:18832707 GO_REF:0000096 MGI:4417868 RGD:9835043 NCBI chr 2:29,619,720...29,740,364
Ensembl chr 2:29,619,720...29,740,978
JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in IMP (MGI:5586645|PMID:24586680) UniProt PMID:24586680 MGI:5586645 NCBI chr 4:48,045,078...48,086,447
Ensembl chr 4:48,045,153...48,086,447
JBrowse link
regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csk c-src tyrosine kinase involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
RGD
PMID:9325302 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 RGD:2303720 NCBI chr 9:57,626,646...57,653,631
Ensembl chr 9:57,626,646...57,653,631
JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 9:92,250,194...92,272,561
Ensembl chr 9:92,249,750...92,272,278
JBrowse link
G Plscr2 phospholipid scramblase 2 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 9:92,275,602...92,297,752
Ensembl chr 9:92,275,602...92,297,752
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor (GEF) 1 acts_upstream_of_or_within IMP
IDA
(MGI:3050742|PMID:15235600)
(MGI:3834538|PMID:17341663)
MGI PMID:15235600 PMID:17341663 MGI:3050742 MGI:3834538 NCBI chr 5:130,171,819...130,214,342
Ensembl chr 5:130,171,798...130,214,342
JBrowse link
regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr3 Fc receptor, IgG, low affinity III ISO RGD PMID:16482158 PMID:22184119 RGD:11041001 RGD:2293335 NCBI chr 1:171,051,169...171,065,915
Ensembl chr 1:171,051,174...171,064,935
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28611
    immune system process 2988
      activation of immune response 448
        immune response-activating signal transduction 349
          immune response-activating cell surface receptor signaling pathway 348
            Fc receptor mediated stimulatory signaling pathway 19
              Fc-gamma receptor signaling pathway involved in phagocytosis + 10
              positive regulation of Fc receptor mediated stimulatory signaling pathway + 7
              positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway 1
              regulation of Fc receptor mediated stimulatory signaling pathway + 14
Path 2
Term Annotations click to browse term
  biological_process 28611
    biological regulation 13269
      regulation of biological process 12620
        positive regulation of biological process 6693
          positive regulation of immune system process 1066
            positive regulation of immune response 701
              activation of immune response 448
                immune response-activating signal transduction 349
                  immune response-activating cell surface receptor signaling pathway 348
                    Fc receptor mediated stimulatory signaling pathway 19
                      Fc-gamma receptor signaling pathway involved in phagocytosis + 10
                      positive regulation of Fc receptor mediated stimulatory signaling pathway + 7
                      positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway 1
                      regulation of Fc receptor mediated stimulatory signaling pathway + 14
paths to the root