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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:Fc receptor mediated stimulatory signaling pathway
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Accession:GO:0002431 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
Synonyms:exact_synonym: Fc receptor mediated stimulatory signalling pathway


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Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER1G Fc epsilon receptor Ig involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14764707) TreeGrafter
MGI		 PMID:14764707 GO_REF:0000118 NCBI chr 1:136,627,672...136,631,696
Ensembl chr 1:140,539,555...140,544,810 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287 		JBrowse link
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYO1G myosin IG involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:45,676,225...45,693,013
Ensembl chr 7:45,740,036...45,759,819 		JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:57,161,299...57,206,672
Ensembl chr 3:58,370,430...58,415,258 		JBrowse link
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD226 CD226 molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:63,238,477...63,379,346
Ensembl chr18:66,533,949...66,627,580 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:16177098 RGD:1578516 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:47,941,134...48,130,538
Ensembl chr11:48,613,761...48,670,494 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO RGD PMID:18832707 RGD:9835043 NCBI chr 1:114,279,255...114,376,977
Ensembl chr 1:125,971,598...125,994,813 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO RGD PMID:18832707 RGD:9835043 NCBI chr 9:102,698,970...102,861,482
Ensembl chr 9:131,337,001...131,495,664 		JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:102,755,388...102,818,686
Ensembl chr12:106,151,969...106,206,879 		JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR4A3 nuclear receptor subfamily 4 group A member 3 involved_in ISO (MGI:5586645|PMID:24586680) UniProt PMID:24586680 MGI:5586645 NCBI chr 9:70,907,056...70,950,221 JBrowse link
regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD47 CD47 molecule involved_in ISO PMID:21401967 ARUK-UCL PMID:21401967 RGD:13792533 NCBI chr 3:105,170,246...105,217,603
Ensembl chr 3:112,104,037...112,143,522 		JBrowse link
G CSK C-terminal Src kinase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:9325302 GO_REF:0000118 RGD:2303720 NCBI chr15:53,724,814...53,745,710
Ensembl chr15:73,342,703...73,363,476 		JBrowse link
G LOC100991644 low affinity immunoglobulin gamma Fc region receptor II-a ISO RGD PMID:16482158 PMID:22184119 RGD:11041001 RGD:2293335 NCBI chr 1:136,892,311...136,906,450 JBrowse link
G LOC100993573 rab5 GDP/GTP exchange factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17341663)
(PMID:15235600)		 Ensembl
MGI		 PMID:15235600 PMID:17341663 GO_REF:0000107 NCBI chr 7:59,268,053...59,344,555
Ensembl chr 7:73,775,002...73,850,446 		JBrowse link
G PLSCR1 phospholipid scramblase 1 involved_in ISO PMID:18579528 UniProt PMID:18579528 RGD:2303650 NCBI chr 3:143,528,967...143,558,468
Ensembl chr 3:151,112,483...151,132,964 		JBrowse link
G PTEN phosphatase and tensin homolog ISO negative regulation RGD PMID:18056380 RGD:2292524 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    immune system process 2406
      activation of immune response 531
        immune response-activating signaling pathway 461
          immune response-activating cell surface receptor signaling pathway 279
            Fc receptor mediated stimulatory signaling pathway 17
              Fc-gamma receptor signaling pathway involved in phagocytosis + 3
              positive regulation of Fc receptor mediated stimulatory signaling pathway + 7
              positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway 1
              regulation of Fc receptor mediated stimulatory signaling pathway + 14
Path 2
Term Annotations click to browse term
  biological_process 16440
    biological regulation 11453
      regulation of biological process 11104
        regulation of immune system process 1530
          positive regulation of immune system process 1079
            positive regulation of immune response 717
              activation of immune response 531
                immune response-activating signaling pathway 461
                  immune response-activating cell surface receptor signaling pathway 279
                    Fc receptor mediated stimulatory signaling pathway 17
                      Fc-gamma receptor signaling pathway involved in phagocytosis + 3
                      positive regulation of Fc receptor mediated stimulatory signaling pathway + 7
                      positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway 1
                      regulation of Fc receptor mediated stimulatory signaling pathway + 14
paths to the root