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ONTOLOGY REPORT - ANNOTATIONS


Term:immune response-activating cell surface receptor signaling pathway
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Accession:GO:0002429 term browser browse the term
Definition:A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a cell capable of activating or perpetuating an immune response.
Synonyms:exact_synonym: activation of immune response by cell surface receptor signaling pathway;   immune response-activating cell surface receptor signalling pathway



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immune response-activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG6 BAG cochaperone 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:23,756,897...23,768,659
Ensembl chr 7:23,756,897...23,775,893
JBrowse link
G NCR3 natural cytotoxicity triggering receptor 3 involved_in IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 7:23,713,333...23,716,988 JBrowse link
antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCAR1 BCAR1 scaffold protein, Cas family member involved_in ISO (PMID:10587647) UniProt PMID:10587647 NCBI chr 6:12,369,332...12,404,822
Ensembl chr 6:12,367,758...12,404,822
JBrowse link
G CD19 CD19 molecule involved_in ISO (PMID:1373518) UniProt PMID:1373518 NCBI chr 3:18,592,785...18,601,273
Ensembl chr 3:18,592,879...18,603,595
JBrowse link
G LAX1 lymphocyte transmembrane adaptor 1 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3578441|PMID:15843560)
GO_Central
MGI
PMID:15843560 PMID:21873635 MGI:3578441 NCBI chr 9:64,460,548...64,473,232
Ensembl chr 9:64,460,652...64,475,179
JBrowse link
G SH2B2 SH2B adaptor protein 2 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:1859033|PMID:10872802)
GO_Central
MGI
PMID:10872802 PMID:21873635 MGI:1859033 NCBI chr 3:9,670,838...9,695,325
Ensembl chr 3:9,668,818...9,695,174
JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (PMID:15214043) BHF-UCL PMID:15214043 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,187,260...54,228,144
JBrowse link
B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1927957|PMID:11120811), (MGI:3839222|PMID:19228876) Ensembl
MGI
PMID:11120811 PMID:19228876 GO_REF:0000107 MGI:1927957 MGI:3839222 NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,711
JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,369,332...12,404,822
Ensembl chr 6:12,367,758...12,404,822
JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:14,688,489...14,745,946
Ensembl chr14:14,688,123...14,746,414
JBrowse link
G BLNK B cell linker involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:107,630,477...107,715,421
Ensembl chr14:107,625,803...107,715,368
JBrowse link
G BMX BMX non-receptor tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:12,044,110...12,096,042
Ensembl chr  X:12,044,349...12,096,638
JBrowse link
G BTK Bruton tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:82,981,512...83,014,475
Ensembl chr  X:82,981,515...83,014,573
JBrowse link
G CD19 CD19 molecule involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:1095647|PMID:9254656)
GO_Central
MGI
PMID:9254656 PMID:21873635 MGI:1095647 NCBI chr 3:18,592,785...18,601,273
Ensembl chr 3:18,592,879...18,603,595
JBrowse link
G CD38 CD38 molecule involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr 8:11,083,682...11,130,783
Ensembl chr 8:11,083,682...11,130,785
JBrowse link
G CD79A CD79a molecule involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(MGI:3521842|PMID:1373499), (MGI:79455|PMID:8626447)
(PMID:21873635)
InterPro
MGI
GO_Central
Ensembl
PMID:1373499 PMID:8626447 PMID:21873635 GO_REF:0000002 GO_REF:0000107 MGI:3521842 MGI:79455 NCBI chr 6:49,996,116...49,999,294
Ensembl chr 6:49,975,957...50,010,059
JBrowse link
G CD79B CD79b molecule involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
(PMID:21873635)
(MGI:3521842|PMID:1373499), (MGI:79455|PMID:8626447)
GO_Central
MGI
InterPro
PMID:1373499 PMID:8626447 PMID:21873635 GO_REF:0000002 MGI:3521842 MGI:79455 NCBI chr12:15,052,966...15,056,441
Ensembl chr12:15,053,007...15,056,441
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:107,283,081...107,288,041
Ensembl chr15:107,282,926...107,289,103
JBrowse link
G ITK IL2 inducible T cell kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:66,010,766...66,082,263
Ensembl chr16:66,010,768...66,082,185
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,288,544...158,518,879
JBrowse link
G KLHL6 kelch like family member 6 involved_in IEA InterPro GO_REF:0000002 NCBI chr13:121,426,618...121,487,260 JBrowse link
G LAT2 linker for activation of T cells family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:11,353,213...11,372,100
Ensembl chr 3:11,352,579...11,372,096
JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:77358|PMID:7499277)
GO_Central
MGI
PMID:7499277 PMID:21873635 MGI:77358 NCBI chr 6:88,719,886...88,745,922
Ensembl chr 6:88,720,176...88,745,917
JBrowse link
G LIME1 Lck interacting transmembrane adaptor 1 acts_upstream_of_or_within ISO (MGI:3769059|PMID:16249387) MGI PMID:16249387 MGI:3769059 NCBI chr17:62,652,618...62,655,342 JBrowse link
G LOC100523213 immunoglobulin lambda-like polypeptide 5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:49,951,542...49,960,517 JBrowse link
G LOC102160313 T-cell receptor delta chain C region involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:76,554,354...76,565,679
Ensembl chr 7:76,469,954...76,673,728
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5471851|PMID:23509253)
(MGI:77358|PMID:7499277)
Ensembl
MGI
PMID:7499277 PMID:23509253 GO_REF:0000107 MGI:5471851 MGI:77358 NCBI chr 4:75,793,273...75,903,710
Ensembl chr 4:75,786,099...75,868,591
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 acts_upstream_of_or_within ISO (MGI:1095647|PMID:9254656) MGI PMID:9254656 MGI:1095647 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,523
JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:96,122,407...96,296,927
Ensembl chr 2:96,122,407...96,296,842
JBrowse link
G MNDA myeloid cell nuclear differentiation antigen involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 4:91,416,410...91,433,243 JBrowse link
G MS4A1 membrane spanning 4-domains A1 involved_in ISO (PMID:18474602) UniProt PMID:18474602 NCBI chr 2:11,216,238...11,229,060 JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr 5:19,677,613...19,720,550
Ensembl chr 5:19,677,875...19,723,132
JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3044463|PMID:15143214)
GO_Central
MGI
PMID:15143214 PMID:21873635 MGI:3044463 NCBI chr 5:6,296,921...6,333,371
Ensembl chr 5:6,298,573...6,336,731
JBrowse link
G NFATC2 nuclear factor of activated T cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:52,743,570...52,907,373
Ensembl chr17:52,743,570...52,906,821
JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,433,146...6,603,092
Ensembl chr 6:6,433,153...6,603,060
JBrowse link
G PLEKHA1 pleckstrin homology domain containing A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:131,960,932...132,016,664
Ensembl chr14:131,946,792...132,016,660
JBrowse link
G PRKCB protein kinase C beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:21,995,227...22,383,628
Ensembl chr 3:21,995,231...22,383,264
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5471851|PMID:23509253)
(MGI:1095647|PMID:9254656)
Ensembl
MGI
PMID:9254656 PMID:23509253 GO_REF:0000107 MGI:1095647 MGI:5471851 NCBI chr 5:63,762,109...63,779,086
Ensembl chr 5:63,762,112...63,808,350
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:77358|PMID:7499277)
(MGI:1095647|PMID:9254656)
Ensembl
MGI
PMID:7499277 PMID:9254656 GO_REF:0000107 MGI:1095647 MGI:77358 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,466,373...21,764,560
JBrowse link
G RFTN1 raftlin, lipid raft linker 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:3,454,448...3,675,072
Ensembl chr13:3,454,448...3,675,021
JBrowse link
G SH2B2 SH2B adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:9,670,838...9,695,325
Ensembl chr 3:9,668,818...9,695,174
JBrowse link
G SYK spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
ISS
(PMID:21873635)
(MGI:77358|PMID:7499277), (MGI:79455|PMID:8626447)
Ensembl
GO_Central
MGI
UniProt
PMID:7499277 PMID:8626447 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:77358 MGI:79455 NCBI chr14:2,103,706...2,160,886
Ensembl chr14:2,056,712...2,161,172
JBrowse link
G TEC tec protein tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:38,051,053...38,182,259
Ensembl chr 8:38,051,056...38,182,182
JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:111,825,071...112,202,833
Ensembl chr 4:111,824,896...112,202,825
JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC7A C-type lectin domain containing 7A acts_upstream_of_or_within ISO (MGI:3042099|PMID:12719478) MGI PMID:12719478 MGI:3042099 NCBI chr 5:61,832,910...61,846,441
Ensembl chr 5:61,832,944...61,846,438
JBrowse link
G FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) involved_in ISO (PMID:21037097) UniProt PMID:21037097 NCBI chr 1:274,106,276...274,111,970
Ensembl chr 1:274,103,877...274,111,970
JBrowse link
G FFAR2 free fatty acid receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:44,899,879...44,904,461
Ensembl chr 6:44,899,336...44,904,459
JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (MGI:3042099|PMID:12719478) MGI PMID:12719478 MGI:3042099 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,991...75,446,850
JBrowse link
complement component C5a signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5AR1 complement C5a receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:53,097,162...53,111,563
Ensembl chr 6:53,097,164...53,117,020
JBrowse link
G C5AR2 complement C5a receptor 2 involved_in IEA GOC GO_REF:0000108 NCBI chr 6:53,118,063...53,125,574
Ensembl chr 6:53,118,470...53,127,102
JBrowse link
complement receptor mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3AR1 complement C3a receptor 1 involved_in ISO (PMID:10571060) UniProt PMID:10571060 NCBI chr 5:63,088,778...63,098,750 JBrowse link
G C5AR1 complement C5a receptor 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:53,097,162...53,111,563
Ensembl chr 6:53,097,164...53,117,020
JBrowse link
G C5AR2 complement C5a receptor 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:53,118,063...53,125,574
Ensembl chr 6:53,118,470...53,127,102
JBrowse link
G CMKLR1 chemerin chemokine-like receptor 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:42,420,166...42,468,080
Ensembl chr14:42,420,176...42,468,065
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:16360013), (PMID:22962438) ARUK-UCL PMID:16360013 PMID:22962438 NCBI chr 9:68,025,673...68,132,162 JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:19,289,385...19,355,606
Ensembl chr 7:19,291,174...19,346,850
JBrowse link
G GPR32 G protein-coupled receptor 32 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:55,519,932...55,522,402
Ensembl chr 6:55,509,963...55,522,400
JBrowse link
G GPR33 G protein-coupled receptor 33 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:68,084,248...68,088,895
Ensembl chr 7:68,084,248...68,089,445
JBrowse link
Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLK BLK proto-oncogene, Src family tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:14,688,489...14,745,946
Ensembl chr14:14,688,123...14,746,414
JBrowse link
G FCER1G Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (MGI:3029067|PMID:14764707) MGI PMID:14764707 MGI:3029067 NCBI chr 4:89,242,467...89,246,344
Ensembl chr 4:89,242,459...89,247,065
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:75,793,273...75,903,710
Ensembl chr 4:75,786,099...75,868,591
JBrowse link
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) involved_in ISO (PMID:2142460) ARUK-UCL PMID:2142460 NCBI chr 4:88,873,762...88,892,964 JBrowse link
G MYO1G myosin IG involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:50,466,450...50,483,520
Ensembl chr18:50,466,449...50,483,518
JBrowse link
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD22 CD22 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:44,820,593...44,834,392
Ensembl chr 6:44,820,683...44,835,956
JBrowse link
G CD300A CD300a molecule involved_in ISO (PMID:21482706) UniProt PMID:21482706 NCBI chr12:6,665,578...6,681,329 JBrowse link
G FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) involved_in ISO (PMID:24169826) ARUK-UCL PMID:24169826 NCBI chr 4:88,873,762...88,892,964 JBrowse link
G FCRL5 Fc receptor like 5 acts_upstream_of_or_within ISO (MGI:5471851|PMID:23509253) MGI PMID:23509253 MGI:5471851 NCBI chr 4:92,578,672...92,631,713 JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,664,869...52,667,643
Ensembl chr12:52,664,873...52,667,610
JBrowse link
G LOC100158069 Fc receptor-like protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:92,460,744...92,506,002
Ensembl chr 4:92,460,859...92,504,038
JBrowse link
G LPXN leupaxin involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:12,534,780...12,582,756
Ensembl chr 2:12,534,840...12,582,745
JBrowse link
G PLCL2 phospholipase C like 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2677607|PMID:14517301) Ensembl
MGI
PMID:14517301 GO_REF:0000107 MGI:2677607 NCBI chr13:3,992,230...4,201,574
Ensembl chr13:3,992,835...4,201,569
JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:39,089,157...39,124,969
Ensembl chr13:39,089,045...39,129,781
JBrowse link
G CD47 CD47 molecule involved_in ISO PMID:21401967 ARUK-UCL PMID:21401967 RGD:13792533 NCBI chr13:151,427,933...151,488,064
Ensembl chr13:151,429,288...151,502,164
JBrowse link
negative regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTN2A2 butyrophilin subfamily 2 member A2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5520006|PMID:23589618) MGI
Ensembl
PMID:23589618 GO_REF:0000107 MGI:5520006 NCBI chr 7:20,954,229...20,968,390
Ensembl chr 7:20,954,173...20,967,794
JBrowse link
G BTNL2 butyrophilin like 2 acts_upstream_of_or_within ISO (MGI:3775536|PMID:16751379) MGI PMID:16751379 MGI:3775536 NCBI chr 7:24,789,988...24,809,920
Ensembl chr 7:24,790,001...24,809,854
JBrowse link
G CBLB Cbl proto-oncogene B involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3041371|PMID:14738763) Ensembl
MGI
PMID:14738763 GO_REF:0000107 MGI:3041371 NCBI chr13:153,480,525...153,700,115
Ensembl chr13:153,395,978...153,700,064
JBrowse link
G CD160 CD160 molecule involved_in ISO (PMID:18193050) UniProt PMID:18193050 NCBI chr 4:99,579,891...99,585,808 JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (PMID:18424730) UniProt PMID:18424730 NCBI chr 6:49,437,308...49,460,614 JBrowse link
G DGKZ diacylglycerol kinase zeta involved_in ISO (MGI:2672999|PMID:12883552) UniProt PMID:12883552 MGI:2672999 NCBI chr 2:16,134,046...16,176,043
Ensembl chr 2:16,134,046...16,176,239
JBrowse link
G DUSP22 dual specificity phosphatase 22 acts_upstream_of_or_within ISO (MGI:5583944|PMID:24714587) MGI PMID:24714587 MGI:5583944 NCBI chr 7:43,437...96,270
Ensembl chr 7:43,486...96,270
JBrowse link
G DUSP3 dual specificity phosphatase 3 involved_in IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr12:19,336,308...19,349,739
Ensembl chr12:19,336,354...19,349,734
JBrowse link
G ELF1 E74 like ETS transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3041371|PMID:14738763) Ensembl
MGI
PMID:14738763 GO_REF:0000107 MGI:3041371 NCBI chr11:25,772,090...25,896,613
Ensembl chr11:25,810,572...25,900,802
JBrowse link
G EZR ezrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:8,403,362...8,452,750
Ensembl chr 1:8,403,453...8,452,750
JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870) ARUK-UCL PMID:18619870 MGI:3803048 NCBI chr 6:87,363,911...87,390,371
Ensembl chr 6:87,363,911...87,390,288
JBrowse link
G LGALS3 galectin 3 involved_in ISO (MGI:4355752|PMID:19706535) BHF-UCL PMID:19706535 MGI:4355752 NCBI chr 1:184,478,639...184,496,155
Ensembl chr 1:184,478,710...184,497,951
JBrowse link
G LOC100517285 leukocyte immunoglobulin-like receptor subfamily A member 6 involved_in ISO (PMID:22387553)
(PMID:16493035)
BHF-UCL
ARUK-UCL
PMID:16493035 PMID:22387553 NCBI chr 6:58,996,449...59,001,088 JBrowse link
G PAWR pro-apoptotic WT1 regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2675524|PMID:12970181) Ensembl
MGI
PMID:12970181 GO_REF:0000107 MGI:2675524 NCBI chr 5:101,693,145...101,797,842
Ensembl chr 5:101,692,143...101,797,835
JBrowse link
G PRNP prion protein involved_in ISO (MGI:4943618|PMID:20145049) BHF-UCL PMID:20145049 MGI:4943618 NCBI chr17:13,694,195...13,705,126
Ensembl chr17:13,693,628...13,705,318
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:96,769,862...96,847,136
Ensembl chr 6:96,770,251...96,847,133
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:18056643) UniProt PMID:18056643 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:82729|PMID:9064344) Ensembl
MGI
PMID:9064344 GO_REF:0000107 MGI:82729 NCBI chr 5:63,762,109...63,779,086
Ensembl chr 5:63,762,112...63,808,350
JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:14,548,489...14,724,823
Ensembl chr 2:14,548,425...14,726,715
JBrowse link
G PVRIG PVR related immunoglobulin domain containing involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:8,230,311...8,232,840
Ensembl chr 3:8,230,328...8,232,836
JBrowse link
G SH2D1A SH2 domain containing 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:101,824,602...101,847,265
Ensembl chr  X:101,824,367...101,849,674
JBrowse link
G SLA2 Src like adaptor 2 involved_in ISO (PMID:11891219) UniProt PMID:11891219 NCBI chr17:39,875,625...39,904,838 JBrowse link
G THY1 Thy-1 cell surface antigen involved_in ISO (MGI:1096761|PMID:9285719) UniProt PMID:9285719 MGI:1096761 NCBI chr 9:46,607,022...46,612,691
Ensembl chr 9:46,607,494...46,612,269
JBrowse link
G UBASH3A ubiquitin associated and SH3 domain containing A involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3041371|PMID:14738763)
GO_Central
MGI
PMID:14738763 PMID:21873635 MGI:3041371 NCBI chr13:205,744,395...205,786,484
Ensembl chr13:205,744,393...205,787,094
JBrowse link
positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPRC protein tyrosine phosphatase receptor type C involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,466,373...21,764,560
JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:1,625,728...1,641,662
Ensembl chr 2:1,506,652...1,641,667
JBrowse link
G CMTM3 CKLF like MARVEL transmembrane domain containing 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3047050|PMID:15196959) Ensembl
MGI
PMID:15196959 GO_REF:0000107 MGI:3047050 NCBI chr 6:27,308,146...27,320,449
Ensembl chr 6:27,308,141...27,317,308
JBrowse link
G FOXP1 forkhead box P1 involved_in ISO (PMID:30111844) ARUK-UCL PMID:30111844 NCBI chr13:52,346,844...52,974,358
Ensembl chr13:52,347,849...52,974,261
JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:6,296,921...6,333,371
Ensembl chr 5:6,298,573...6,336,731
JBrowse link
G PRKCB protein kinase C beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:21,995,227...22,383,628
Ensembl chr 3:21,995,231...22,383,264
JBrowse link
G PRKCH protein kinase C eta involved_in ISO (PMID:18780722) UniProt PMID:18780722 NCBI chr 1:190,205,041...190,439,433
Ensembl chr 1:190,205,678...190,439,433
JBrowse link
G SLC39A10 solute carrier family 39 member 10 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5586914|PMID:25074919) Ensembl
MGI
PMID:25074919 GO_REF:0000107 MGI:5586914 NCBI chr15:99,584,830...99,724,621
Ensembl chr15:99,584,839...99,726,404
JBrowse link
G STAP1 signal transducing adaptor family member 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:65,318,861...65,372,838
Ensembl chr 8:65,332,522...65,392,965
JBrowse link
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD226 CD226 molecule involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:152,872,878...152,977,162
Ensembl chr 1:152,882,761...152,979,848
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:16177098 RGD:1578516 NCBI chr 4:75,793,273...75,903,710
Ensembl chr 4:75,786,099...75,868,591
JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:6271154|PMID:25568335) UniProt PMID:25568335 MGI:6271154 NCBI chr 5:79,356,046...79,412,235
Ensembl chr 5:79,356,047...79,412,233
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,466,373...21,764,560
JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in ISO (MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:3774343 NCBI chr 2:14,548,489...14,724,823
Ensembl chr 2:14,548,425...14,726,715
JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO RGD PMID:18832707 RGD:9835043 NCBI chr 4:108,675,537...108,750,952
Ensembl chr 4:108,676,685...108,749,725
JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO RGD PMID:18832707 RGD:9835043 NCBI chr 1:271,494,243...271,624,609
Ensembl chr 1:271,494,248...271,600,879
JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR4A3 nuclear receptor subfamily 4 group A member 3 involved_in ISO (MGI:5586645|PMID:24586680) UniProt PMID:24586680 MGI:5586645 NCBI chr 1:241,569,867...241,611,735
Ensembl chr 1:241,569,905...241,611,734
JBrowse link
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3640996|PMID:11435465) Ensembl
MGI
PMID:11435465 GO_REF:0000107 MGI:3640996 NCBI chr17:47,044,492...47,072,232
Ensembl chr17:47,044,495...47,072,245
JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:130,645,427...130,653,317
Ensembl chr 4:130,645,174...130,657,995
JBrowse link
G CARD11 caspase recruitment domain family member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:2,145,178...2,266,377
Ensembl chr 3:2,145,177...2,266,356
JBrowse link
G CCR7 C-C motif chemokine receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:21,857,286...21,869,211
Ensembl chr12:21,856,467...21,872,535
JBrowse link
G CD226 CD226 molecule involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:152,872,878...152,977,162
Ensembl chr 1:152,882,761...152,979,848
JBrowse link
G CD81 CD81 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:1,625,728...1,641,662
Ensembl chr 2:1,506,652...1,641,667
JBrowse link
G CYLD CYLD lysine 63 deubiquitinase acts_upstream_of_or_within ISO (MGI:3656194|PMID:16501569) MGI PMID:16501569 MGI:3656194 NCBI chr 6:34,058,091...34,121,939
Ensembl chr 6:34,059,941...34,121,272
JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr  X:125,035,575...125,056,445
Ensembl chr  X:125,036,508...125,056,453
JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:50,580,016...50,593,518
Ensembl chr 6:50,580,022...50,593,544
JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:51,317,386...51,358,665 JBrowse link
G PRKD2 protein kinase D2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:52,559,066...52,599,174
Ensembl chr 6:52,559,393...52,599,132
JBrowse link
G RAB29 RAB29, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:66,448,854...66,458,766
Ensembl chr 9:66,445,843...66,483,838
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,471
JBrowse link
G RPS3 ribosomal protein S3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:9,612,939...9,630,404
Ensembl chr 9:9,616,456...9,630,413
JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:19,966,623...20,017,476
Ensembl chr 5:19,904,914...20,017,419
JBrowse link
G TRAT1 T cell receptor associated transmembrane adaptor 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:11390434)
(PMID:21873635)
MGI
GO_Central
PMID:11390434 PMID:21873635 NCBI chr13:150,629,942...150,666,842
Ensembl chr13:150,614,587...150,667,328
JBrowse link
regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLK BLK proto-oncogene, Src family tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:14,688,489...14,745,946
Ensembl chr14:14,688,123...14,746,414
JBrowse link
G CD19 CD19 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:18,592,785...18,601,273
Ensembl chr 3:18,592,879...18,603,595
JBrowse link
G GCSAM germinal center associated signaling and motility involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr13:147,623,212...147,643,942
Ensembl chr13:147,623,212...147,643,942
JBrowse link
G GCSAML germinal center associated signaling and motility like involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:56,690,853...56,744,757
Ensembl chr 2:56,687,496...56,744,620
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:75,793,273...75,903,710
Ensembl chr 4:75,786,099...75,868,591
JBrowse link
regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSK C-terminal Src kinase ISO RGD PMID:9325302 RGD:2303720 NCBI chr 7:58,736,473...58,755,034
Ensembl chr 7:58,736,529...58,755,260
JBrowse link
G PLSCR1 phospholipid scramblase 1 involved_in ISO PMID:18579528 UniProt PMID:18579528 RGD:2303650 NCBI chr13:86,836,288...86,869,569
Ensembl chr13:86,649,586...86,869,297
JBrowse link
G RABGEF1 RAB guanine nucleotide exchange factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3834538|PMID:17341663)
(MGI:3050742|PMID:15235600)
Ensembl
MGI
PMID:15235600 PMID:17341663 GO_REF:0000107 MGI:3050742 MGI:3834538 NCBI chr 3:16,308,112...16,376,604
Ensembl chr 3:16,308,112...16,376,587
JBrowse link
regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL10 BCL10 immune signaling adaptor acts_upstream_of_or_within ISO (MGI:3629264|PMID:14614861) MGI PMID:14614861 MGI:3629264 NCBI chr 4:130,645,427...130,653,317
Ensembl chr 4:130,645,174...130,657,995
JBrowse link
G CD300A CD300a molecule involved_in ISO (PMID:22046970) UniProt PMID:22046970 NCBI chr12:6,665,578...6,681,329 JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (MGI:3042327|PMID:14752163) MGI PMID:14752163 MGI:3042327 NCBI chr 6:88,719,886...88,745,922
Ensembl chr 6:88,720,176...88,745,917
JBrowse link
G MALT1 MALT1 paracaspase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3629264|PMID:14614861) Ensembl
MGI
PMID:14614861 GO_REF:0000107 MGI:3629264 NCBI chr 1:162,076,933...162,144,915
Ensembl chr 1:162,076,951...162,144,880
JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:116,204,807...116,292,455
Ensembl chr 9:116,209,094...116,292,366
JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 acts_upstream_of ISO (MGI:5920164|PMID:28598420) MGI PMID:28598420 MGI:5920164 NCBI chr 5:19,966,623...20,017,476
Ensembl chr 5:19,904,914...20,017,419
JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC7A C-type lectin domain containing 7A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:61,832,910...61,846,441
Ensembl chr 5:61,832,944...61,846,438
JBrowse link
G KLRD1 killer cell lectin like receptor D1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:61,662,083...61,673,109
Ensembl chr 5:61,646,505...61,672,115
JBrowse link
G KLRK1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2450811|PMID:12645935) Ensembl
MGI
PMID:12645935 GO_REF:0000107 MGI:2450811 NCBI chr 5:61,646,691...61,655,386
Ensembl chr 5:61,623,200...61,656,195
JBrowse link
G LOC100519314 natural killer cells antigen CD94 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:61,724,744...61,736,667 JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,433,146...6,603,092
Ensembl chr 6:6,433,153...6,603,060
JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:2,103,706...2,160,886
Ensembl chr14:2,056,712...2,161,172
JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 6:45,309,199...45,312,562
Ensembl chr 6:45,309,197...45,312,537
JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 6:45,309,199...45,312,562
Ensembl chr 6:45,309,197...45,312,537
JBrowse link
T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3798766|PMID:18305217) Ensembl
MGI
PMID:18305217 GO_REF:0000107 MGI:3798766 NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,711
JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:130,645,427...130,653,317
Ensembl chr 4:130,645,174...130,657,995
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3773982|PMID:18228248) Ensembl
MGI
PMID:18228248 GO_REF:0000107 MGI:3773982 NCBI chr18:8,957,963...9,132,558
Ensembl chr18:8,957,959...9,132,553
JBrowse link
G BTN1A1 butyrophilin subfamily 1 member A1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:20,977,940...20,985,300
Ensembl chr 7:20,977,223...20,985,300
JBrowse link
G BTN2A2 butyrophilin subfamily 2 member A2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:20,954,229...20,968,390
Ensembl chr 7:20,954,173...20,967,794
JBrowse link
G BTNL2 butyrophilin like 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:24,789,988...24,809,920
Ensembl chr 7:24,790,001...24,809,854
JBrowse link
G BTNL9 butyrophilin like 9 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:57,728,520...57,745,249
Ensembl chr 2:57,728,523...57,745,246
JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3691409|PMID:17028169) Ensembl
MGI
PMID:17028169 GO_REF:0000107 MGI:3691409 NCBI chr 5:14,875,524...14,888,224
Ensembl chr 5:14,874,238...14,888,224
JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3526783|PMID:15637280), (MGI:3691409|PMID:17028169) Ensembl
MGI
PMID:15637280 PMID:17028169 GO_REF:0000107 MGI:3526783 MGI:3691409 NCBI chr15:402,801...455,691
Ensembl chr15:186,315...459,856
JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (MGI:5544872|PMID:23793062) MGI PMID:23793062 MGI:5544872 NCBI chr 6:28,265,130...28,277,649
Ensembl chr 6:28,264,320...28,279,703
JBrowse link
G CBLB Cbl proto-oncogene B involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2665211|PMID:12697763) Ensembl
MGI
PMID:12697763 GO_REF:0000107 MGI:2665211 NCBI chr13:153,480,525...153,700,115
Ensembl chr13:153,395,978...153,700,064
JBrowse link
G CD247 CD247 molecule involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3640996|PMID:11435465)
GO_Central
MGI
PMID:11435465 PMID:21873635 MGI:3640996 NCBI chr 4:83,494,266...83,586,887
Ensembl chr 4:83,458,417...83,586,650
JBrowse link
G CD276 CD276 molecule involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:59,703,283...59,733,910
Ensembl chr 7:59,629,638...59,733,778
JBrowse link
G CD28 CD28 molecule involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
(PMID:21873635)
(MGI:5544872|PMID:23793062)
GO_Central
MGI
Ensembl
PMID:21873635 PMID:23793062 GO_REF:0000107 MGI:5544872 NCBI chr15:107,128,103...107,155,431
Ensembl chr15:107,128,208...107,162,943
JBrowse link
G CD3E CD3e molecule acts_upstream_of_or_within ISO (MGI:3577956|PMID:10485657) MGI PMID:10485657 MGI:3577956 NCBI chr 9:45,619,730...45,633,972
Ensembl chr 9:45,619,481...45,635,379
JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3798766|PMID:18305217) Ensembl
MGI
PMID:18305217 GO_REF:0000107 MGI:3798766 NCBI chr14:50,528,950...50,558,664
Ensembl chr14:50,528,954...50,558,663
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:107,283,081...107,288,041
Ensembl chr15:107,282,926...107,289,103
JBrowse link
G DENND1B DENN domain containing 1B involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:20,391,507...20,635,808
Ensembl chr10:20,395,462...20,636,247
JBrowse link
G EIF2B1 eukaryotic translation initiation factor 2B subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:29,355,497...29,367,918
Ensembl chr14:29,332,233...29,367,918
JBrowse link
G EIF2B2 eukaryotic translation initiation factor 2B subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:98,203,820...98,246,199
Ensembl chr 7:98,203,814...98,259,183
JBrowse link
G EIF2B3 eukaryotic translation initiation factor 2B subunit gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:166,353,918...166,487,581
Ensembl chr 6:166,353,934...166,494,698
JBrowse link
G EIF2B4 eukaryotic translation initiation factor 2B subunit delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:111,781,661...111,786,377
Ensembl chr 3:111,780,332...111,786,377
JBrowse link
G EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:122,060,408...122,070,327
Ensembl chr13:122,060,484...122,070,708
JBrowse link
G ERMAP erythroblast membrane associated protein involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:168,596,522...168,643,437
Ensembl chr 6:168,599,597...168,613,830
JBrowse link
G FOXP3 forkhead box P3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1331533|PMID:10072494), (MGI:1929588|PMID:11265635) Ensembl
MGI
PMID:10072494 PMID:11265635 GO_REF:0000107 MGI:1331533 MGI:1929588 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,782...43,328,735
JBrowse link
G FYB1 FYN binding protein 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:24,332,539...24,507,768
Ensembl chr16:24,333,032...24,507,740
JBrowse link
G FYB2 FYN binding protein 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:155,566,996...155,684,814
Ensembl chr 6:155,477,131...155,679,156
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:77,584,675...77,810,605
Ensembl chr 1:77,585,439...77,810,581
JBrowse link
G GATA3 GATA binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:63,367,684...63,397,977
Ensembl chr10:63,367,660...63,388,859
JBrowse link
G HHLA2 HERV-H LTR-associating 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:151,153,982...151,298,324
Ensembl chr13:151,153,261...151,298,330
JBrowse link
G HRAS HRas proto-oncogene, GTPase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5013687|PMID:21444916) Ensembl
MGI
PMID:21444916 GO_REF:0000107 MGI:5013687 NCBI chr 2:299,662...302,539
Ensembl chr 2:299,660...302,501
JBrowse link
G ICOSLG inducible T cell costimulator ligand involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:207,106,202...207,115,886 JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (MGI:5013687|PMID:21444916) MGI PMID:21444916 MGI:5013687 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,848...32,482,752
JBrowse link
G ITK IL2 inducible T cell kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:66,010,766...66,082,263
Ensembl chr16:66,010,768...66,082,185
JBrowse link
G KHDRBS1 KH RNA binding domain containing, signal transduction associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:88,530,364...88,572,467
Ensembl chr 6:88,530,387...88,572,464
JBrowse link
G LCP2 lymphocyte cytosolic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:53,696,974...53,741,736
Ensembl chr16:53,697,020...53,741,726
JBrowse link
G LOC100512174 butyrophilin-like protein 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:24,271,839...24,290,750 JBrowse link
G LOC100513291 butyrophilin, subfamily 1, member involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:24,778,319...24,790,468 JBrowse link
G LOC100513868 butyrophilin-like protein 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:24,764,445...24,773,528 JBrowse link
G LOC100736850 butyrophilin subfamily 1 member A1-like involved_in IBA (PMID:21873635) GO_Central PMID:21873635
G LOC102158214 butyrophilin subfamily 1 member A1-like involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:24,725,373...24,759,750 JBrowse link
G LOC106508184 butyrophilin subfamily 1 member A1-like involved_in IBA (PMID:21873635) GO_Central PMID:21873635
G MALT1 MALT1 paracaspase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:162,076,933...162,144,915
Ensembl chr 1:162,076,951...162,144,880
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 acts_upstream_of_or_within ISO (MGI:82729|PMID:9064344) MGI PMID:9064344 MGI:82729 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,523
JBrowse link
G MOG myelin oligodendrocyte glycoprotein involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:22,595,565...22,606,137
Ensembl chr 7:22,595,508...22,612,761
JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr 6:45,298,289...45,307,471
Ensembl chr 6:45,296,039...45,306,317
JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr13:157,261,419...157,273,119
Ensembl chr13:157,261,418...157,294,478
JBrowse link
G NRAS NRAS proto-oncogene, GTPase acts_upstream_of_or_within ISO (MGI:5013687|PMID:21444916) MGI PMID:21444916 MGI:5013687 NCBI chr 4:105,845,913...105,853,769
Ensembl chr 4:105,845,872...105,858,227
JBrowse link
G PDE4B phosphodiesterase 4B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:146,167,262...146,720,105
Ensembl chr 6:146,166,681...146,720,127
JBrowse link
G PDE4D phosphodiesterase 4D involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:37,897,300...39,406,534
Ensembl chr16:37,897,300...39,154,586
JBrowse link
G PLCG1 phospholipase C gamma 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3531056|PMID:15728238) Ensembl
MGI
PMID:15728238 GO_REF:0000107 MGI:3531056 NCBI chr17:43,810,003...43,844,553
Ensembl chr17:43,809,677...43,844,555
JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3531056|PMID:15728238) Ensembl
MGI
PMID:15728238 GO_REF:0000107 MGI:3531056 NCBI chr 6:6,433,146...6,603,092
Ensembl chr 6:6,433,153...6,603,060
JBrowse link
G PRAM1 PML-RARA regulated adaptor molecule 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:70,803,092...70,812,859
Ensembl chr 2:70,796,820...70,813,230
JBrowse link
G PRKD2 protein kinase D2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:52,559,066...52,599,174
Ensembl chr 6:52,559,393...52,599,132
JBrowse link
G PSEN1 presenilin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3760494|PMID:17698590) Ensembl
MGI
PMID:17698590 GO_REF:0000107 MGI:3760494 NCBI chr 7:96,478,179...96,567,884
Ensembl chr 7:96,478,181...96,569,132
JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (MGI:3760494|PMID:17698590) MGI PMID:17698590 MGI:3760494 NCBI chr10:14,532,556...14,561,862
Ensembl chr10:14,532,550...14,561,858
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3042327|PMID:14752163)
GO_Central
MGI
PMID:14752163 PMID:21873635 MGI:3042327 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,466,373...21,764,560
JBrowse link
G RBCK1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,784,018...34,801,228
Ensembl chr17:34,784,016...34,801,231
JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:116,204,807...116,292,455
Ensembl chr 9:116,209,094...116,292,366
JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:263,769,403...263,822,101
Ensembl chr 1:263,772,168...263,822,104
JBrowse link
G RFTN1 raftlin, lipid raft linker 1 involved_in ISO (MGI:3850290|PMID:19414744) UniProt PMID:19414744 MGI:3850290 NCBI chr13:3,454,448...3,675,072
Ensembl chr13:3,454,448...3,675,021
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2176422|PMID:11894098) Ensembl
MGI
PMID:11894098 GO_REF:0000107 MGI:2176422 NCBI chr 4:47,026,558...47,075,133
Ensembl chr 4:47,027,092...47,074,725
JBrowse link
G SHB SH2 domain containing adaptor protein B involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5617929|PMID:24645804) Ensembl
MGI
PMID:24645804 GO_REF:0000107 MGI:5617929 NCBI chr 1:238,680,804...238,826,424 JBrowse link
G SKAP1 src kinase associated phosphoprotein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:24,371,699...24,680,280
Ensembl chr12:24,350,349...24,680,237
JBrowse link
G SPN sialophorin involved_in ISO PMID:12496963 ARUK-UCL PMID:12496963 RGD:1358565 NCBI chr 3:17,978,731...17,982,222 JBrowse link
G SPPL3 signal peptide peptidase like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:40,699,931...40,870,288
Ensembl chr14:40,699,936...40,822,761
JBrowse link
G STK11 serine/threonine kinase 11 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5003385|PMID:21487392) Ensembl
MGI
PMID:21487392 GO_REF:0000107 MGI:5003385 NCBI chr 2:77,229,888...77,249,322
Ensembl chr 2:77,230,372...77,249,327
JBrowse link
G STOML2 stomatin like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:235,891,479...235,894,944
Ensembl chr 1:235,890,679...235,894,625
JBrowse link
G TEC tec protein tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:38,051,053...38,182,259
Ensembl chr 8:38,051,056...38,182,182
JBrowse link
G THEMIS thymocyte selection associated involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 1:35,333,210...35,530,710
Ensembl chr 1:35,333,454...35,519,870
JBrowse link
G THEMIS2 thymocyte selection associated family member 2 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:5446993|PMID:22732588)
GO_Central
MGI
PMID:21873635 PMID:22732588 MGI:5446993 NCBI chr 6:85,010,879...85,027,934
Ensembl chr 6:85,010,883...85,030,723
JBrowse link
G THY1 Thy-1 cell surface antigen involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:46,607,022...46,612,691
Ensembl chr 9:46,607,494...46,612,269
JBrowse link
G TNFRSF21 TNF receptor superfamily member 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,020,219...42,091,521
Ensembl chr 7:42,020,227...42,091,516
JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:24,602,749...24,628,263
Ensembl chr 2:24,602,783...24,626,072
JBrowse link
G TXK TXK tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:37,977,222...38,047,876
Ensembl chr 8:37,977,972...38,046,933
JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chr 5:89,673,306...89,716,345
Ensembl chr 5:89,673,573...89,714,281
JBrowse link
G VTCN1 V-set domain containing T cell activation inhibitor 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:103,390,547...103,584,847
Ensembl chr 4:103,412,571...103,584,684
JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:68,000,792...68,142,533
Ensembl chr 5:68,001,104...68,140,757
JBrowse link
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:893249|PMID:9208839) Ensembl
MGI
PMID:9208839 GO_REF:0000107 MGI:893249 NCBI chr 3:56,515,446...56,541,806
Ensembl chr 3:56,515,449...56,541,740
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:93,541,334...93,551,200
Ensembl chr 6:93,541,334...93,551,195
JBrowse link
G ZNF683 zinc finger protein 683 involved_in ISO (PMID:26179882) UniProt PMID:26179882 NCBI chr 6:83,756,865...83,765,905
Ensembl chr 6:83,758,978...83,765,855
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16581
    immune system process 2310
      activation of immune response 265
        immune response-activating signal transduction 190
          immune response-activating cell surface receptor signaling pathway 189
            Fc receptor mediated stimulatory signaling pathway + 17
            antigen receptor-mediated signaling pathway + 160
            complement receptor mediated signaling pathway + 8
            innate immune response activating cell surface receptor signaling pathway + 10
Path 2
Term Annotations click to browse term
  biological_process 16581
    biological regulation 12071
      regulation of biological process 11445
        positive regulation of biological process 6173
          positive regulation of immune system process 821
            positive regulation of immune response 474
              activation of immune response 265
                immune response-activating signal transduction 190
                  immune response-activating cell surface receptor signaling pathway 189
                    Fc receptor mediated stimulatory signaling pathway + 17
                    antigen receptor-mediated signaling pathway + 160
                    complement receptor mediated signaling pathway + 8
                    innate immune response activating cell surface receptor signaling pathway + 10
paths to the root