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ONTOLOGY REPORT - ANNOTATIONS


Term:immune response-activating cell surface receptor signaling pathway
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Accession:GO:0002429 term browser browse the term
Definition:A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a cell capable of activating or perpetuating an immune response.
Synonyms:exact_synonym: activation of immune response by cell surface receptor signaling pathway;   immune response-activating cell surface receptor signalling pathway



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immune response-activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG6 BAG cochaperone 6 involved_in ISO (PMID:18852879) UniProt PMID:18852879 NCBI chr12:1,126,730...1,141,978
Ensembl chr12:1,126,732...1,137,896
JBrowse link
G NCR3 natural cytotoxicity triggering receptor 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:1,086,698...1,104,268
Ensembl chr12:1,086,841...1,089,481
JBrowse link
antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCAR1 BCAR1 scaffold protein, Cas family member involved_in ISO (PMID:10587647) UniProt PMID:10587647 NCBI chr 5:75,463,906...75,499,557
Ensembl chr 5:75,463,926...75,512,476
JBrowse link
G CD19 CD19 molecule involved_in ISO (PMID:1373518) UniProt PMID:1373518 NCBI chr 6:18,419,092...18,425,524
Ensembl chr 6:18,418,241...18,425,400
JBrowse link
G LAX1 lymphocyte transmembrane adaptor 1 acts_upstream_of_or_within ISO (MGI:3578441|PMID:15843560) MGI PMID:15843560 MGI:3578441 NCBI chr38:429,062...438,069
Ensembl chr38:429,528...436,696
JBrowse link
G SH2B2 SH2B adaptor protein 2 acts_upstream_of_or_within ISO (MGI:1859033|PMID:10872802) MGI PMID:10872802 MGI:1859033 NCBI chr 6:7,795,756...7,820,010
Ensembl chr 6:7,795,373...7,819,843
JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (PMID:15214043) BHF-UCL PMID:15214043 NCBI chr 1:107,423,388...107,426,464
Ensembl chr 1:107,422,424...107,426,464
JBrowse link
B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1927957|PMID:11120811), (MGI:3839222|PMID:19228876) Ensembl
MGI
PMID:11120811 PMID:19228876 GO_REF:0000107 MGI:1927957 MGI:3839222 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307
JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member involved_in ISO (PMID:9020138) UniProt PMID:9020138 NCBI chr 5:75,463,906...75,499,557
Ensembl chr 5:75,463,926...75,512,476
JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:876631)
(PMID:23555801)
UniProt
ARUK-UCL
PMID:876631 PMID:23555801 NCBI chr25:26,336,253...26,357,494
Ensembl chr25:26,336,892...26,358,015
JBrowse link
G BLNK B cell linker involved_in ISO (PMID:9697839)
(PMID:11606584)
UniProt
ARUK-UCL
PMID:9697839 PMID:11606584 NCBI chr28:9,622,438...9,700,335
Ensembl chr28:9,622,752...9,732,639
JBrowse link
G BTK Bruton tyrosine kinase involved_in ISO (PMID:15509800) ARUK-UCL PMID:15509800 NCBI chr  X:75,270,952...75,302,663
Ensembl chr  X:75,270,979...75,302,562
JBrowse link
G CD19 CD19 molecule acts_upstream_of_or_within
involved_in
ISO (MGI:1095647|PMID:9254656)
(MGI:5476553|PMID:23499492)
MGI
UniProt
PMID:9254656 PMID:23499492 MGI:1095647 MGI:5476553 NCBI chr 6:18,419,092...18,425,524
Ensembl chr 6:18,418,241...18,425,400
JBrowse link
G CD38 CD38 molecule involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr 3:64,529,129...64,577,755
Ensembl chr 3:64,529,721...64,578,099
JBrowse link
G CD79A CD79a molecule involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3521842|PMID:1373499), (MGI:79455|PMID:8626447)
GO_Central
MGI
PMID:1373499 PMID:8626447 PMID:21873635 MGI:3521842 MGI:79455 NCBI chr 1:112,411,281...112,414,827
Ensembl chr 1:112,411,281...112,427,381
JBrowse link
G CD79B CD79b molecule acts_upstream_of_or_within ISO (MGI:3521842|PMID:1373499), (MGI:79455|PMID:8626447) MGI PMID:1373499 PMID:8626447 MGI:3521842 MGI:79455 NCBI chr 9:11,834,230...11,844,946
Ensembl chr 9:11,842,190...11,844,843
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874
JBrowse link
G ITK IL2 inducible T cell kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:52,902,886...52,966,465
Ensembl chr 4:52,902,871...52,966,542
JBrowse link
G KLHL6 kelch like family member 6 involved_in ISO (MGI:3603885|PMID:16166635) UniProt PMID:16166635 MGI:3603885 NCBI chr34:16,443,282...16,556,991
Ensembl chr34:16,446,944...16,504,549
JBrowse link
G LAT2 linker for activation of T cells family member 2 involved_in ISO (PMID:12514734) HGNC-UCL PMID:12514734 NCBI chr 6:6,160,939...6,175,271
Ensembl chr 6:6,161,542...6,173,294
JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (MGI:77358|PMID:7499277) MGI PMID:7499277 MGI:77358 NCBI chr 2:68,940,816...68,964,585
Ensembl chr 2:68,941,249...68,964,567
JBrowse link
G LIME1 Lck interacting transmembrane adaptor 1 acts_upstream_of_or_within ISO (MGI:3769059|PMID:16249387) MGI PMID:16249387 MGI:3769059 NCBI chr24:47,269,922...47,272,288 JBrowse link
G LOC100687054 immunoglobulin lambda-like polypeptide 5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:28,793,360...28,804,589 JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (MGI:77358|PMID:7499277)
(MGI:5471851|PMID:23509253)
MGI PMID:7499277 PMID:23509253 MGI:5471851 MGI:77358 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1095647|PMID:9254656) Ensembl
MGI
PMID:9254656 GO_REF:0000107 MGI:1095647 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998
JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:19,778,997...19,948,203
Ensembl chr 3:19,779,007...19,943,852
JBrowse link
G MNDA myeloid cell nuclear differentiation antigen involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr38:22,921,729...22,934,276
Ensembl chr38:22,921,732...22,934,286
JBrowse link
G MS4A1 membrane spanning 4-domains A1 involved_in ISO (PMID:18474602) UniProt PMID:18474602 NCBI chr21:50,722,142...50,734,934
Ensembl chr21:50,722,041...50,733,704
JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439
JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 acts_upstream_of_or_within ISO (MGI:3044463|PMID:15143214) MGI PMID:15143214 MGI:3044463 NCBI chr10:23,008,084...23,047,227
Ensembl chr10:23,008,393...23,045,565
JBrowse link
G NFATC2 nuclear factor of activated T cells 2 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr24:37,606,977...37,734,813
Ensembl chr24:37,609,561...37,771,132
JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049
JBrowse link
G PLEKHA1 pleckstrin homology domain containing A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:32,025,791...32,081,824
Ensembl chr28:32,026,350...32,081,835
JBrowse link
G PRKCB protein kinase C beta involved_in ISO (MGI:3626015|PMID:12118249) UniProt PMID:12118249 MGI:3626015 NCBI chr 6:21,742,970...22,064,360
Ensembl chr 6:21,742,973...22,065,185
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within ISO (MGI:5471851|PMID:23509253)
(MGI:1095647|PMID:9254656)
MGI PMID:9254656 PMID:23509253 MGI:1095647 MGI:5471851 NCBI chr27:38,084,976...38,101,552
Ensembl chr27:38,084,980...38,101,937
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within
involved_in
ISO (MGI:77358|PMID:7499277)
(MGI:3687418|PMID:8692271)
(MGI:1095647|PMID:9254656)
MGI
UniProt
PMID:7499277 PMID:8692271 PMID:9254656 MGI:1095647 MGI:3687418 MGI:77358 NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124
JBrowse link
G RFTN1 raftlin, lipid raft linker 1 involved_in ISO (PMID:12805216) UniProt PMID:12805216 NCBI chr23:26,272,103...26,472,610
Ensembl chr23:26,282,392...26,472,536
JBrowse link
G SH2B2 SH2B adaptor protein 2 involved_in ISO (PMID:9233773) UniProt PMID:9233773 NCBI chr 6:7,795,756...7,820,010
Ensembl chr 6:7,795,373...7,819,843
JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in
ISO (MGI:77358|PMID:7499277), (MGI:79455|PMID:8626447)
(PMID:15509800)
MGI
ARUK-UCL
PMID:7499277 PMID:8626447 PMID:15509800 MGI:77358 MGI:79455 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583
JBrowse link
G TEC tec protein tyrosine kinase involved_in ISO (PMID:10518561) UniProt PMID:10518561 NCBI chr13:43,978,964...44,111,256
Ensembl chr13:43,978,573...44,062,795
JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chr 6:43,663,787...44,002,362
Ensembl chr 6:43,559,985...44,000,811
JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC7A C-type lectin domain containing 7A acts_upstream_of_or_within ISO (MGI:3042099|PMID:12719478) MGI PMID:12719478 MGI:3042099 NCBI chr27:35,852,685...35,885,673
Ensembl chr27:35,853,099...36,007,157
JBrowse link
G FCN2 ficolin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:50,868,942...50,876,001
Ensembl chr 9:50,868,973...50,875,792
JBrowse link
G FFAR2 free fatty acid receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:117,197,535...117,201,613
Ensembl chr 1:117,198,289...117,199,284
JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (MGI:3042099|PMID:12719478) MGI PMID:12719478 MGI:3042099 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241
JBrowse link
complement component C5a signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5AR1 complement C5a receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:108,659,637...108,704,217
Ensembl chr 1:108,659,637...108,675,401
JBrowse link
G C5AR2 complement C5a receptor 2 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:108,644,195...108,652,628
Ensembl chr 1:108,644,945...108,645,958
JBrowse link
complement receptor mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3AR1 complement C3a receptor 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr27:37,431,745...37,439,858
Ensembl chr27:37,433,792...37,435,246
JBrowse link
G C5AR1 complement C5a receptor 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:108,659,637...108,704,217
Ensembl chr 1:108,659,637...108,675,401
JBrowse link
G C5AR2 complement C5a receptor 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:108,644,195...108,652,628
Ensembl chr 1:108,644,945...108,645,958
JBrowse link
G FPR2 formyl peptide receptor 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:105,343,096...105,353,563
Ensembl chr 1:105,344,463...105,372,070
JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:22,495,001...22,556,264
Ensembl chr35:22,495,073...22,554,105
JBrowse link
G LOC490269 complement receptor type 2 involved_in ISO (PMID:16360013), (PMID:22962438) ARUK-UCL PMID:16360013 PMID:22962438 NCBI chr 7:6,456,238...6,480,672 JBrowse link
Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER1G Fc fragment of IgE receptor Ig involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3029067|PMID:14764707) Ensembl
MGI
PMID:14764707 GO_REF:0000107 MGI:3029067 NCBI chr38:21,267,841...21,271,036
Ensembl chr38:21,268,001...21,270,940
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507
JBrowse link
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCGR2B Fc fragment of IgG receptor IIb involved_in ISO (PMID:2142460) ARUK-UCL PMID:2142460 NCBI chr38:20,980,777...20,994,403 JBrowse link
G MYO1G myosin IG involved_in ISO (MGI:5586792|PMID:23038771) UniProt PMID:23038771 MGI:5586792
innate immune response activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC484309 leukocyte immunoglobulin-like receptor subfamily A member 6 involved_in ISO (PMID:27572839) UniProt PMID:27572839 NCBI chr 1:102,995,743...103,014,085 JBrowse link
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD22 CD22 molecule involved_in ISO (PMID:24169826)
(PMID:26017478)
ARUK-UCL PMID:24169826 PMID:26017478 NCBI chr 1:117,261,730...117,285,775
Ensembl chr 1:117,261,740...117,284,818
JBrowse link
G CD300A CD300a molecule involved_in ISO (PMID:21482706) UniProt PMID:21482706 NCBI chr 9:5,952,428...5,976,328 JBrowse link
G FCGR2B Fc fragment of IgG receptor IIb involved_in ISO (PMID:24169826) ARUK-UCL PMID:24169826 NCBI chr38:20,980,777...20,994,403 JBrowse link
G FCRL3 Fc receptor like 3 involved_in ISO (PMID:19843936) UniProt PMID:19843936 NCBI chr 7:40,599,319...40,625,939 JBrowse link
G FCRL5 Fc receptor like 5 acts_upstream_of_or_within ISO (MGI:5471851|PMID:23509253) MGI PMID:23509253 MGI:5471851 NCBI chr 7:40,685,554...40,719,195
Ensembl chr 7:40,696,448...40,716,314
JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in ISO (MGI:5896692|PMID:28039360) UniProt PMID:28039360 MGI:5896692 NCBI chr 5:32,273,169...32,275,915
Ensembl chr 5:32,273,173...32,275,580
JBrowse link
G LPXN leupaxin involved_in ISO (MGI:3722965|PMID:17640867)
(PMID:17640867)
UniProt PMID:17640867 MGI:3722965 NCBI chr18:37,809,612...37,847,958
Ensembl chr18:37,810,007...37,847,306
JBrowse link
G PLCL2 phospholipase C like 2 acts_upstream_of_or_within ISO (MGI:2677607|PMID:14517301) MGI PMID:14517301 MGI:2677607 NCBI chr23:25,814,392...25,999,666
Ensembl chr23:25,814,862...25,999,749
JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,123,577...33,166,831
Ensembl chr20:33,130,723...33,166,792
JBrowse link
G CD47 CD47 molecule involved_in ISO PMID:21401967 ARUK-UCL PMID:21401967 RGD:13792533 NCBI chr33:13,315,984...13,362,971
Ensembl chr33:13,319,266...13,363,580
JBrowse link
negative regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTNL2 butyrophilin like 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3775536|PMID:16751379) Ensembl
MGI
PMID:16751379 GO_REF:0000107 MGI:3775536 NCBI chr12:2,085,589...2,106,787
Ensembl chr12:2,086,324...2,107,124
JBrowse link
G CBLB Cbl proto-oncogene B involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3041371|PMID:14738763) Ensembl
MGI
PMID:14738763 GO_REF:0000107 MGI:3041371 NCBI chr33:11,255,453...11,665,755
Ensembl chr33:11,199,863...11,530,810
JBrowse link
G CD160 CD160 molecule involved_in ISO (PMID:18193050) UniProt PMID:18193050 NCBI chr17:58,548,137...58,564,077
Ensembl chr17:58,555,851...58,563,341
JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (PMID:18424730) UniProt PMID:18424730 NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830
JBrowse link
G DGKZ diacylglycerol kinase zeta involved_in ISO (MGI:2672999|PMID:12883552) UniProt PMID:12883552 MGI:2672999 NCBI chr18:43,088,169...43,103,820
Ensembl chr18:43,088,525...43,129,294
JBrowse link
G DUSP22 dual specificity phosphatase 22 acts_upstream_of_or_within ISO (MGI:5583944|PMID:24714587) MGI PMID:24714587 MGI:5583944 NCBI chr35:678,320...733,225
Ensembl chr35:678,155...732,397
JBrowse link
G DUSP3 dual specificity phosphatase 3 involved_in ISO (PMID:12447358) UniProt PMID:12447358 NCBI chr 9:19,518,302...19,531,000
Ensembl chr 9:19,518,746...19,527,624
JBrowse link
G ELF1 E74 like ETS transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3041371|PMID:14738763) Ensembl
MGI
PMID:14738763 GO_REF:0000107 MGI:3041371 NCBI chr22:9,565,912...9,671,017
Ensembl chr22:9,592,978...9,670,271
JBrowse link
G EZR ezrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:48,160,206...48,210,036
Ensembl chr 1:48,160,206...48,210,036
JBrowse link
G GBP1 guanylate binding protein 1 involved_in ISO (PMID:24337748) UniProt PMID:24337748 NCBI chr 6:59,378,069...59,393,388
Ensembl chr 6:59,273,592...59,393,229
JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870) ARUK-UCL PMID:18619870 MGI:3803048 NCBI chr 2:70,188,382...70,215,361
Ensembl chr 2:70,152,739...70,333,073
JBrowse link
G LGALS3 galectin 3 involved_in ISO (MGI:4355752|PMID:19706535) BHF-UCL PMID:19706535 MGI:4355752 NCBI chr 8:30,977,438...30,994,711
Ensembl chr 8:30,983,633...30,994,705
JBrowse link
G LOC100855640 butyrophilin subfamily 2 member A2 acts_upstream_of_or_within ISO (MGI:5520006|PMID:23589618) MGI PMID:23589618 MGI:5520006 NCBI chr35:24,251,221...24,265,040
Ensembl chr35:24,251,799...24,262,496
JBrowse link
G LOC484306 leukocyte immunoglobulin-like receptor subfamily B member 3 involved_in ISO (PMID:22387553)
(PMID:16493035)
BHF-UCL
ARUK-UCL
PMID:16493035 PMID:22387553 NCBI chr 1:102,779,562...102,786,924 JBrowse link
G PAWR pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO (MGI:2675524|PMID:12970181) MGI PMID:12970181 MGI:2675524 NCBI chr15:22,114,014...22,159,287 JBrowse link
G PHPT1 phosphohistidine phosphatase 1 involved_in ISO (PMID:18796614) BHF-UCL PMID:18796614 NCBI chr 9:48,736,310...48,737,771
Ensembl chr 9:48,736,333...48,737,725
JBrowse link
G PRNP prion protein involved_in ISO (MGI:4943618|PMID:20145049) BHF-UCL PMID:20145049 MGI:4943618 NCBI chr24:16,845,224...16,862,319
Ensembl chr24:16,846,207...16,859,815
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:18056643) UniProt PMID:18056643 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within ISO (MGI:82729|PMID:9064344) MGI PMID:9064344 MGI:82729 NCBI chr27:38,084,976...38,101,552
Ensembl chr27:38,084,980...38,101,937
JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in ISO (PMID:11259588), (PMID:9780142)
(PMID:12913111)
(MGI:4942249|PMID:12913111)
UniProt PMID:9780142 PMID:11259588 PMID:12913111 MGI:4942249 NCBI chr18:41,586,262...41,635,386
Ensembl chr18:41,586,112...41,635,308
JBrowse link
G PVRIG PVR related immunoglobulin domain containing involved_in ISO (PMID:26755705) UniProt PMID:26755705 NCBI chr 6:9,314,959...9,324,544
Ensembl chr 6:9,318,163...9,319,499
JBrowse link
G SH2D1A SH2 domain containing 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:95,739,568...95,762,117
Ensembl chr  X:95,739,669...95,760,698
JBrowse link
G SLA2 Src like adaptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:25,396,187...25,426,789
Ensembl chr24:25,396,900...25,422,467
JBrowse link
G THY1 Thy-1 cell surface antigen involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:14,503,902...14,509,113
Ensembl chr 5:14,503,902...14,509,113
JBrowse link
G UBASH3A ubiquitin associated and SH3 domain containing A involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3041371|PMID:14738763)
GO_Central
MGI
PMID:14738763 PMID:21873635 MGI:3041371 NCBI chr31:36,735,790...36,778,405
Ensembl chr31:36,735,835...36,778,405
JBrowse link
positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPRC protein tyrosine phosphatase receptor type C involved_in ISO (MGI:3687418|PMID:8692271) UniProt PMID:8692271 MGI:3687418 NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124
JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule involved_in ISO (MGI:5476553|PMID:23499492)
(PMID:20237408)
UniProt PMID:20237408 PMID:23499492 MGI:5476553 NCBI chr18:46,466,484...46,474,236
Ensembl chr18:46,466,499...46,473,868
JBrowse link
G CMTM3 CKLF like MARVEL transmembrane domain containing 3 acts_upstream_of_or_within ISO (MGI:3047050|PMID:15196959) MGI PMID:15196959 MGI:3047050 NCBI chr 5:82,660,995...82,667,360
Ensembl chr 5:82,661,256...82,667,372
JBrowse link
G FOXP1 forkhead box P1 involved_in ISO (PMID:30111844) ARUK-UCL PMID:30111844 NCBI chr20:20,438,631...21,020,516
Ensembl chr20:20,788,433...21,016,397
JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr10:23,008,084...23,047,227
Ensembl chr10:23,008,393...23,045,565
JBrowse link
G PRKCB protein kinase C beta involved_in ISO (MGI:3700457|PMID:16301747) UniProt PMID:16301747 MGI:3700457 NCBI chr 6:21,742,970...22,064,360
Ensembl chr 6:21,742,973...22,065,185
JBrowse link
G PRKCH protein kinase C eta involved_in ISO (PMID:18780722) UniProt PMID:18780722 NCBI chr 8:36,185,430...36,452,893
Ensembl chr 8:36,219,212...36,451,777
JBrowse link
G SLC39A10 solute carrier family 39 member 10 acts_upstream_of_or_within ISO (MGI:5586914|PMID:25074919) MGI PMID:25074919 MGI:5586914 NCBI chr37:5,482,200...5,521,104
Ensembl chr37:5,482,177...5,521,110
JBrowse link
G STAP1 signal transducing adaptor family member 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:58,091,457...58,148,902
Ensembl chr13:58,091,477...58,133,711
JBrowse link
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD226 CD226 molecule involved_in ISO (PMID:16831868) BHF-UCL PMID:16831868 NCBI chr 1:8,348,628...8,437,520
Ensembl chr 1:8,351,207...8,435,145
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:16177098 RGD:1578516 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507
JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:33,192,261...33,243,034
Ensembl chr10:33,191,602...33,242,669
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in ISO (MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:3774343 NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124
JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in ISO (MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:3774343 NCBI chr18:41,586,262...41,635,386
Ensembl chr18:41,586,112...41,635,308
JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO RGD PMID:18832707 RGD:9835043 NCBI chr17:63,725,812...63,795,359
Ensembl chr17:63,726,248...63,746,881
JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO RGD PMID:18832707 RGD:9835043 NCBI chr 9:52,429,204...52,566,775
Ensembl chr 9:52,450,597...52,563,778
JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR4A3 nuclear receptor subfamily 4 group A member 3 involved_in ISO (MGI:5586645|PMID:24586680) UniProt PMID:24586680 MGI:5586645 NCBI chr11:56,806,506...56,846,997
Ensembl chr11:56,812,804...56,847,689
JBrowse link
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of_or_within ISO (MGI:3640996|PMID:11435465) MGI PMID:11435465 MGI:3640996 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160
JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:62,712,937...62,723,852
Ensembl chr 6:62,712,971...62,722,368
JBrowse link
G CARD11 caspase recruitment domain family member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:14,273,115...14,331,029
Ensembl chr 6:14,210,114...14,332,094
JBrowse link
G CCR7 C-C motif chemokine receptor 7 involved_in ISO (MGI:3847607|PMID:17785582) BHF-UCL PMID:17785582 MGI:3847607 NCBI chr 9:22,077,976...22,092,818
Ensembl chr 9:22,068,775...22,090,656
JBrowse link
G CD226 CD226 molecule involved_in ISO (PMID:26755705) UniProt PMID:26755705 NCBI chr 1:8,348,628...8,437,520
Ensembl chr 1:8,351,207...8,435,145
JBrowse link
G CD81 CD81 molecule involved_in ISO (PMID:23858057) UniProt PMID:23858057 NCBI chr18:46,466,484...46,474,236
Ensembl chr18:46,466,499...46,473,868
JBrowse link
G CYLD CYLD lysine 63 deubiquitinase acts_upstream_of_or_within ISO (MGI:3656194|PMID:16501569) MGI PMID:16501569 MGI:3656194 NCBI chr 2:64,561,684...64,628,829
Ensembl chr 2:64,562,503...64,628,175
JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (PMID:18287044), (PMID:27777308) UniProt PMID:18287044 PMID:27777308 NCBI chr  X:122,232,052...122,253,499
Ensembl chr  X:122,235,878...122,250,562
JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:111,391,464...111,407,612
Ensembl chr 1:111,391,159...111,407,701
JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:110,543,140...110,569,168
Ensembl chr 1:110,543,247...110,569,143
JBrowse link
G PRKD2 protein kinase D2 involved_in ISO (MGI:4849903|PMID:20819079) UniProt PMID:20819079 MGI:4849903 NCBI chr 1:109,206,400...109,241,529
Ensembl chr 1:109,207,067...109,330,007
JBrowse link
G RAB29 RAB29, member RAS oncogene family involved_in ISO (PMID:26021297) ParkinsonsUK-UCL PMID:26021297 NCBI chr38:2,196,618...2,204,150
Ensembl chr38:2,198,040...2,203,896
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875
JBrowse link
G RPS3 ribosomal protein S3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:23,180,515...23,187,034
Ensembl chr21:23,180,515...23,187,034
JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr27:424,836...460,114
Ensembl chr27:424,715...460,097
JBrowse link
G TRAT1 T cell receptor associated transmembrane adaptor 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:11390434)
(PMID:21873635)
MGI
GO_Central
PMID:11390434 PMID:21873635 NCBI chr33:14,033,597...14,068,309
Ensembl chr33:14,033,657...14,067,974
JBrowse link
regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD19 CD19 molecule involved_in ISO (PMID:9382888)
(MGI:1100180|PMID:9382888)
UniProt PMID:9382888 MGI:1100180 NCBI chr 6:18,419,092...18,425,524
Ensembl chr 6:18,418,241...18,425,400
JBrowse link
G GCSAM germinal center associated signaling and motility involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr33:16,742,708...16,754,445
Ensembl chr33:16,744,212...16,754,026
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507
JBrowse link
regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSK C-terminal Src kinase involved_in IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:9325302 PMID:21873635 RGD:2303720 NCBI chr30:37,851,269...37,870,382
Ensembl chr30:37,852,046...37,870,378
JBrowse link
G PLSCR1 phospholipid scramblase 1 involved_in ISO PMID:18579528 UniProt PMID:18579528 RGD:2303650 NCBI chr23:41,639,938...41,668,972
Ensembl chr23:41,599,843...41,669,112
JBrowse link
G RABGEF1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (MGI:3050742|PMID:15235600)
(MGI:3834538|PMID:17341663)
MGI PMID:15235600 PMID:17341663 MGI:3050742 MGI:3834538 NCBI chr 6:1,064,694...1,159,906
Ensembl chr 6:1,064,655...1,179,547
JBrowse link
regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL10 BCL10 immune signaling adaptor acts_upstream_of_or_within ISO (MGI:3629264|PMID:14614861) MGI PMID:14614861 MGI:3629264 NCBI chr 6:62,712,937...62,723,852
Ensembl chr 6:62,712,971...62,722,368
JBrowse link
G CD300A CD300a molecule involved_in ISO (PMID:22046970) UniProt PMID:22046970 NCBI chr 9:5,952,428...5,976,328 JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (MGI:3042327|PMID:14752163) MGI PMID:14752163 MGI:3042327 NCBI chr 2:68,940,816...68,964,585
Ensembl chr 2:68,941,249...68,964,567
JBrowse link
G MALT1 MALT1 paracaspase acts_upstream_of_or_within ISO (MGI:3629264|PMID:14614861) MGI PMID:14614861 MGI:3629264 NCBI chr 1:17,351,458...17,412,591
Ensembl chr 1:17,354,926...17,403,927
JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:3580753|PMID:15917799) BHF-UCL PMID:15917799 MGI:3580753 NCBI chr 7:25,265,836...25,312,417
Ensembl chr 7:25,233,235...25,305,174
JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 acts_upstream_of ISO (MGI:5920164|PMID:28598420) MGI PMID:28598420 MGI:5920164 NCBI chr27:424,836...460,114
Ensembl chr27:424,715...460,097
JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KLRD1 killer cell lectin like receptor D1 involved_in ISS UniProt GO_REF:0000024 NCBI chr27:35,700,879...35,707,270
Ensembl chr27:35,701,185...35,706,720
JBrowse link
G KLRK1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2450811|PMID:12645935) Ensembl
MGI
PMID:12645935 GO_REF:0000107 MGI:2450811 NCBI chr27:35,634,938...35,658,978
Ensembl chr27:35,639,280...35,658,882
JBrowse link
G LOC486692 NKG2-A/NKG2-B type II integral membrane protein-like involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chr27:35,534,620...35,584,473 JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049
JBrowse link
G SYK spleen associated tyrosine kinase involved_in ISO (MGI:3844414|PMID:19136564) ARUK-UCL PMID:19136564 MGI:3844414 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583
JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chr 1:116,757,271...116,760,453
Ensembl chr 1:116,757,289...116,772,325
JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chr 1:116,757,271...116,760,453
Ensembl chr 1:116,757,289...116,772,325
JBrowse link
T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3798766|PMID:18305217) Ensembl
MGI
PMID:18305217 GO_REF:0000107 MGI:3798766 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307
JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:62,712,937...62,723,852
Ensembl chr 6:62,712,971...62,722,368
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (MGI:3773982|PMID:18228248) MGI PMID:18228248 MGI:3773982 NCBI chr16:8,222,909...8,318,179
Ensembl chr16:8,222,907...8,317,906
JBrowse link
G BTNL2 butyrophilin like 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:2,085,589...2,106,787
Ensembl chr12:2,086,324...2,107,124
JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 acts_upstream_of_or_within ISO (MGI:3691409|PMID:17028169) MGI PMID:17028169 MGI:3691409 NCBI chr27:5,705,587...5,714,620
Ensembl chr27:5,706,064...5,717,647
JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 acts_upstream_of_or_within ISO (MGI:3526783|PMID:15637280), (MGI:3691409|PMID:17028169) MGI PMID:15637280 PMID:17028169 MGI:3526783 MGI:3691409 NCBI chr19:52,987,170...53,116,410
Ensembl chr19:52,993,618...53,116,140
Ensembl chr19:52,993,618...53,116,140
JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (MGI:5544872|PMID:23793062) MGI PMID:23793062 MGI:5544872 NCBI chr 5:81,792,683...81,804,274
Ensembl chr 5:81,792,155...81,804,152
JBrowse link
G CBLB Cbl proto-oncogene B involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2665211|PMID:12697763) Ensembl
MGI
PMID:12697763 GO_REF:0000107 MGI:2665211 NCBI chr33:11,255,453...11,665,755
Ensembl chr33:11,199,863...11,530,810
JBrowse link
G CD247 CD247 molecule acts_upstream_of_or_within ISO (MGI:3640996|PMID:11435465) MGI PMID:11435465 MGI:3640996 NCBI chr 7:30,961,169...30,972,143 JBrowse link
G CD28 CD28 molecule involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:5544872|PMID:23793062)
GO_Central
MGI
PMID:21873635 PMID:23793062 MGI:5544872 NCBI chr37:12,503,849...12,536,362
Ensembl chr37:12,503,811...12,532,854
JBrowse link
G CD3E CD3e molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3577956|PMID:10485657) Ensembl
MGI
PMID:10485657 GO_REF:0000107 MGI:3577956 NCBI chr 5:15,403,724...15,415,259
Ensembl chr 5:15,403,710...15,415,260
JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3798766|PMID:18305217) Ensembl
MGI
PMID:18305217 GO_REF:0000107 MGI:3798766 NCBI chr26:30,542,276...30,582,479
Ensembl chr26:30,545,311...30,581,964
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874
JBrowse link
G DENND1B DENN domain containing 1B involved_in ISO (MGI:5751612|PMID:26774822)
(PMID:26774822)
UniProt PMID:26774822 MGI:5751612 NCBI chr 7:5,008,249...5,267,392
Ensembl chr 7:4,999,430...5,262,630
JBrowse link
G EIF2B1 eukaryotic translation initiation factor 2B subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:6,011,280...6,022,562
Ensembl chr26:6,011,301...6,022,518
JBrowse link
G EIF2B2 eukaryotic translation initiation factor 2B subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:48,110,521...48,117,175
Ensembl chr 8:48,110,050...48,116,686
JBrowse link
G EIF2B3 eukaryotic translation initiation factor 2B subunit gamma involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chr15:15,337,421...15,481,427
Ensembl chr15:15,337,483...15,481,425
JBrowse link
G EIF2B4 eukaryotic translation initiation factor 2B subunit delta involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chr17:21,321,329...21,326,357
Ensembl chr17:21,321,349...21,326,244
JBrowse link
G EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:17,038,163...17,047,390
Ensembl chr34:17,038,203...17,046,928
JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of_or_within ISO (MGI:1331533|PMID:10072494), (MGI:1929588|PMID:11265635) MGI PMID:10072494 PMID:11265635 MGI:1331533 MGI:1929588 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758
JBrowse link
G FYB2 FYN binding protein 2 involved_in ISO (PMID:27335501) UniProt PMID:27335501 NCBI chr 5:52,680,685...52,804,155
Ensembl chr 5:52,680,645...52,801,700
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:68,105,060...68,316,630
Ensembl chr12:68,075,184...68,316,541
JBrowse link
G GATA3 GATA binding protein 3 involved_in ISO (MGI:5285154|PMID:20696860) UniProt PMID:20696860 MGI:5285154 NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760
JBrowse link
G HLA-DRB1 MHC class II DLA DRB1 beta chain involved_in ISO (PMID:32341563) UniProt PMID:32341563 NCBI chr12:2,151,409...2,164,564 JBrowse link
G HRAS HRas proto-oncogene, GTPase acts_upstream_of_or_within ISO (MGI:5013687|PMID:21444916) MGI PMID:21444916 MGI:5013687 NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717
JBrowse link
G ICOSLG inducible T cell costimulator ligand involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr31:38,084,861...38,094,743 JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (MGI:5013687|PMID:21444916) MGI PMID:21444916 MGI:5013687 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G ITK IL2 inducible T cell kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:52,902,886...52,966,465
Ensembl chr 4:52,902,871...52,966,542
JBrowse link
G KHDRBS1 KH RNA binding domain containing, signal transduction associated 1 involved_in ISO (PMID:9045636) UniProt PMID:9045636 NCBI chr 2:69,108,822...69,148,067
Ensembl chr 2:69,123,663...69,148,073
JBrowse link
G LCP2 lymphocyte cytosolic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:41,611,674...41,656,792
Ensembl chr 4:41,611,775...41,656,364
JBrowse link
G MALT1 MALT1 paracaspase involved_in ISO (MGI:6142401|PMID:25282160)
(PMID:15125833)
UniProt PMID:15125833 PMID:25282160 MGI:6142401 NCBI chr 1:17,351,458...17,412,591
Ensembl chr 1:17,354,926...17,403,927
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:82729|PMID:9064344) Ensembl
MGI
PMID:9064344 GO_REF:0000107 MGI:82729 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998
JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr 1:116,763,371...116,770,683
Ensembl chr 1:116,757,289...116,772,325
JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr33:8,147,160...8,154,401
Ensembl chr33:8,073,840...8,154,561
JBrowse link
G NRAS NRAS proto-oncogene, GTPase acts_upstream_of_or_within ISO (MGI:5013687|PMID:21444916) MGI PMID:21444916 MGI:5013687 NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788
JBrowse link
G PDE4B phosphodiesterase 4B involved_in ISO (PMID:17404263) BHF-UCL PMID:17404263 NCBI chr 5:44,063,145...44,606,070
Ensembl chr 5:44,065,106...44,500,999
JBrowse link
G PDE4D phosphodiesterase 4D involved_in ISO (PMID:17404263) BHF-UCL PMID:17404263 NCBI chr 2:45,843,767...47,245,263
Ensembl chr 2:45,846,294...46,949,912
JBrowse link
G PLCG1 phospholipase C gamma 1 acts_upstream_of_or_within ISO (MGI:3531056|PMID:15728238) MGI PMID:15728238 MGI:3531056 NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714
JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3531056|PMID:15728238) Ensembl
MGI
PMID:15728238 GO_REF:0000107 MGI:3531056 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049
JBrowse link
G PRAM1 PML-RARA regulated adaptor molecule 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:53,035,389...53,047,126 JBrowse link
G PRKD2 protein kinase D2 involved_in ISO (PMID:17077180) BHF-UCL PMID:17077180 NCBI chr 1:109,206,400...109,241,529
Ensembl chr 1:109,207,067...109,330,007
JBrowse link
G PSEN1 presenilin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3760494|PMID:17698590) Ensembl
MGI
PMID:17698590 GO_REF:0000107 MGI:3760494 NCBI chr 8:46,495,551...46,569,532
Ensembl chr 8:46,495,624...46,569,532
JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (MGI:3760494|PMID:17698590) MGI PMID:17698590 MGI:3760494 NCBI chr 7:38,147,157...38,163,023
Ensembl chr 7:38,147,173...38,166,722
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3042327|PMID:14752163)
GO_Central
MGI
PMID:14752163 PMID:21873635 MGI:3042327 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124
JBrowse link
G RBCK1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in ISO (PMID:20005846) UniProt PMID:20005846 NCBI chr24:20,423,378...20,440,985
Ensembl chr24:20,423,988...20,441,114
JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr 7:25,265,836...25,312,417
Ensembl chr 7:25,233,235...25,305,174
JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr 9:59,881,889...59,943,271
Ensembl chr 9:59,881,966...59,929,341
JBrowse link
G RFTN1 raftlin, lipid raft linker 1 involved_in ISO (MGI:3850290|PMID:19414744) UniProt PMID:19414744 MGI:3850290 NCBI chr23:26,272,103...26,472,610
Ensembl chr23:26,282,392...26,472,536
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in
ISO (MGI:2176422|PMID:11894098)
(MGI:5285496|PMID:21469090)
MGI
UniProt
PMID:11894098 PMID:21469090 MGI:2176422 MGI:5285496 NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333
JBrowse link
G RNF31 ring finger protein 31 involved_in ISO (PMID:20005846) UniProt PMID:20005846 NCBI chr 8:4,141,501...4,151,999 JBrowse link
G SHB SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO (MGI:5617929|PMID:24645804) MGI PMID:24645804 MGI:5617929 NCBI chr11:54,189,580...54,329,004
Ensembl chr11:54,189,843...54,329,325
JBrowse link
G SKAP1 src kinase associated phosphoprotein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:24,412,820...24,700,579
Ensembl chr 9:24,412,820...24,700,734
JBrowse link
G SPN sialophorin involved_in ISO PMID:12496963 ARUK-UCL PMID:12496963 RGD:1358565 NCBI chr 6:17,770,303...17,774,946 JBrowse link
G SPPL3 signal peptide peptidase like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:16,620,236...16,760,616
Ensembl chr26:16,621,455...16,760,623
JBrowse link
G STK11 serine/threonine kinase 11 acts_upstream_of_or_within ISO (MGI:5003385|PMID:21487392) MGI PMID:21487392 MGI:5003385 NCBI chr20:57,558,966...57,579,163
Ensembl chr20:57,559,424...57,579,118
JBrowse link
G STOML2 stomatin like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:51,675,963...51,679,313
Ensembl chr11:51,675,963...51,679,199
JBrowse link
G THEMIS thymocyte selection associated involved_in ISO (MGI:4352756|PMID:19597499), (MGI:4352757|PMID:19597498) UniProt PMID:19597498 PMID:19597499 MGI:4352756 MGI:4352757 NCBI chr 1:66,363,172...66,540,272
Ensembl chr 1:66,363,125...66,540,327
JBrowse link
G THEMIS2 thymocyte selection associated family member 2 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:5446993|PMID:22732588)
GO_Central
MGI
PMID:21873635 PMID:22732588 MGI:5446993 NCBI chr 2:72,465,719...72,501,962
Ensembl chr 2:72,464,026...72,502,928
JBrowse link
G THY1 Thy-1 cell surface antigen involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:14,503,902...14,509,113
Ensembl chr 5:14,503,902...14,509,113
JBrowse link
G TNFRSF21 TNF receptor superfamily member 21 involved_in ISO (MGI:2137821|PMID:11485735) UniProt PMID:11485735 MGI:2137821 NCBI chr12:15,343,953...15,408,230 JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chr18:31,674,242...31,689,160
Ensembl chr18:31,675,391...31,688,641
JBrowse link
G TXK TXK tyrosine kinase involved_in ISO (MGI:1335923|PMID:10213685) UniProt PMID:10213685 MGI:1335923 NCBI chr13:43,911,881...43,977,499
Ensembl chr13:43,914,534...43,976,655
JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chr10:41,470,073...41,470,738
Ensembl chr10:41,470,073...41,470,738
JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 involved_in ISO (MGI:6141968|PMID:27400149) BHF-UCL PMID:27400149 MGI:6141968 NCBI chr27:42,764,184...42,914,591
Ensembl chr27:42,765,181...42,912,806
JBrowse link
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within ISO (MGI:893249|PMID:9208839) MGI PMID:9208839 MGI:893249 NCBI chr10:44,887,416...44,913,845
Ensembl chr10:44,887,433...44,900,071
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:4,972,369...4,984,218
Ensembl chr15:4,972,956...4,980,371
JBrowse link
G ZNF683 zinc finger protein 683 involved_in ISO (PMID:26179882) UniProt PMID:26179882 NCBI chr 2:73,656,842...73,667,621
Ensembl chr 2:73,658,525...73,667,605
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13875
    immune system process 2185
      activation of immune response 242
        immune response-activating signal transduction 176
          immune response-activating cell surface receptor signaling pathway 175
            Fc receptor mediated stimulatory signaling pathway + 16
            antigen receptor-mediated signaling pathway + 147
            complement receptor mediated signaling pathway + 6
            innate immune response activating cell surface receptor signaling pathway + 11
Path 2
Term Annotations click to browse term
  biological_process 13875
    biological regulation 10011
      regulation of biological process 9451
        positive regulation of biological process 5945
          positive regulation of immune system process 795
            positive regulation of immune response 450
              activation of immune response 242
                immune response-activating signal transduction 176
                  immune response-activating cell surface receptor signaling pathway 175
                    Fc receptor mediated stimulatory signaling pathway + 16
                    antigen receptor-mediated signaling pathway + 147
                    complement receptor mediated signaling pathway + 6
                    innate immune response activating cell surface receptor signaling pathway + 11
paths to the root