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ONTOLOGY REPORT - ANNOTATIONS

Term:T cell mediated immune response to tumor cell
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Accession:GO:0002424 term browser browse the term
Definition:An immune response mediated by a T cell triggered in response to the presence of a tumor cell.
Comment:Note that this term includes tolerogenic responses to tumor cells mediated by responding T cells.


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negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc4 mucin 4, cell surface associated IDA RGD PMID:10232613 RGD:2303754 NCBI chr11:68,008,245...68,053,242 JBrowse link
negative regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor involved_in ISO
ISS
IEA		 (PMID:32818467)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:32818467 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:28813410), (PMID:28813417) RGD PMID:28813410 PMID:28813417 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:32818467)
(MGI:6508501|PMID:21469114), (MGI:6508513|PMID:28405502)		 RGD PMID:21469114 PMID:28405502 PMID:32818467 MGI:6508501 MGI:6508513 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Pdcd1 programmed cell death 1 involved_in ISO (PMID:38377992) RGD PMID:38377992 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISO
ISS		 (PMID:38377992)
GO_REF:0000024		 RGD
UniProt		 PMID:38377992 GO_REF:0000024 NCBI chr 5:38,962,721...38,995,134
Ensembl chr 5:38,962,171...38,995,199 		JBrowse link
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mr1 major histocompatibility complex, class I-related involved_in ISO
IEA		 (PMID:31959982)
GO_REF:0000107		 RGD
Ensembl		 PMID:31959982 GO_REF:0000107 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970 		JBrowse link
G Slc22a13 solute carrier family 22 member 13 involved_in ISO (PMID:19282870) RGD PMID:19282870 NCBI chr 8:118,922,367...118,934,020
Ensembl chr 8:118,922,367...118,953,635 		JBrowse link
positive regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule acts_upstream_of_or_within ISO (PMID:7774619) RGD PMID:7774619 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Fbxo38 F-box protein 38 involved_in ISO (PMID:30487606) RGD PMID:30487606 NCBI chr18:55,956,950...56,004,013
Ensembl chr18:55,956,959...56,003,961 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:10663613) RGD PMID:10663613 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:30282837) RGD PMID:30282837 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5470371|PMID:23108142)		 UniProt
RGD		 PMID:23108142 GO_REF:0000024 MGI:5470371 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:1402688), (PMID:17189421), (PMID:20364150) RGD PMID:1402688 PMID:17189421 PMID:20364150 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    response to stimulus 10920
      immune response 2112
        immune response to tumor cell 36
          T cell mediated immune response to tumor cell 14
            T cell mediated cytotoxicity directed against tumor cell target + 4
            T cell tolerance induction to tumor cell + 0
            negative regulation of T cell mediated immune response to tumor cell + 6
            positive regulation of T cell mediated immune response to tumor cell + 6
            regulation of T cell mediated immune response to tumor cell + 13
Path 2
Term Annotations click to browse term
  biological_process 20413
    immune system process 3017
      immune response 2112
        adaptive immune response 574
          adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 482
            T cell mediated immunity 167
              T cell mediated immune response to tumor cell 14
                T cell mediated cytotoxicity directed against tumor cell target + 4
                T cell tolerance induction to tumor cell + 0
                negative regulation of T cell mediated immune response to tumor cell + 6
                positive regulation of T cell mediated immune response to tumor cell + 6
                regulation of T cell mediated immune response to tumor cell + 13
paths to the root