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ONTOLOGY REPORT - ANNOTATIONS

Term:response to tumor cell
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Accession:GO:0002347 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.


show annotations for term's descendants           Sort by:
response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnmt histamine N-methyltransferase IEP RGD PMID:3111198 RGD:2316837 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012 		JBrowse link
cellular response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igfbpl1 insulin-like growth factor binding protein-like 1 involved_in ISO (PMID:15845387) RGD PMID:15845387 NCBI chr 5:60,076,428...60,091,833
Ensembl chr 5:60,076,429...60,091,833 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:11306509) RGD PMID:11306509 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Notch2 notch receptor 2 involved_in ISO
IEA
ISS		 (PMID:11306509)
GO_REF:0000107
GO_REF:0000024
GO_REF:0000002		 RGD
Ensembl
UniProt
InterPro		 PMID:11306509 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Txnip thioredoxin interacting protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:18541147)		 UniProt
RGD		 PMID:18541147 GO_REF:0000024 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
defense response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi3 ABI family, member 3 involved_in ISO (PMID:21223585)
(MGI:6508500|PMID:21223585)		 RGD PMID:21223585 MGI:6508500 NCBI chr10:80,769,819...80,780,816
Ensembl chr10:80,769,822...80,780,816 		JBrowse link
G Abi3bp ABI family member 3 binding protein involved_in ISS GO_REF:0000024 ARUK-UCL GO_REF:0000024 NCBI chr11:43,912,187...44,128,888
Ensembl chr11:43,913,043...44,128,929 		JBrowse link
G Dapk1 death associated protein kinase 1 involved_in ISO (PMID:30429596) RGD PMID:30429596 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Dlec1 DLEC1 cilia and flagella associated protein involved_in ISO
IEA		 (PMID:30429596)
GO_REF:0000107		 RGD
Ensembl		 PMID:30429596 GO_REF:0000107 NCBI chr 8:118,826,429...118,873,183
Ensembl chr 8:118,826,466...118,873,655 		JBrowse link
G Klf4 KLF transcription factor 4 involved_in ISO (PMID:30429596) RGD PMID:30429596 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:19787053) RGD PMID:19787053 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Plk5 polo-like kinase 5 involved_in ISO (PMID:21245385)
(MGI:4946977|PMID:21245385)		 RGD PMID:21245385 MGI:4946977 NCBI chr 7:9,346,777...9,367,923
Ensembl chr 7:9,346,777...9,355,196 		JBrowse link
G Prdx2 peroxiredoxin 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:30429596)		 Ensembl
RGD		 PMID:30429596 GO_REF:0000107 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Prf1 perforin 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:66009|PMID:8164737)		 UniProt
Ensembl
RGD		 PMID:8164737 GO_REF:0000024 GO_REF:0000107 MGI:66009 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701 		JBrowse link
G Rbms3 RNA binding motif, single stranded interacting protein 3 involved_in ISO (PMID:28409548) RGD PMID:28409548 NCBI chr 8:116,305,227...117,625,730
Ensembl chr 8:116,309,882...117,625,423 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:28362429) RGD PMID:28362429 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO
IEA		 (PMID:28362429), (PMID:28481873), (PMID:30429596)
GO_REF:0000107		 RGD
Ensembl		 PMID:28362429 PMID:28481873 PMID:30429596 GO_REF:0000107 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
detection of tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO
IBA		 (PMID:15811952)
GO_REF:0000033
(MGI:3689781|PMID:15811952)		 RGD
GO_Central		 PMID:15811952 GO_REF:0000033 MGI:3689781 NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343 		JBrowse link
immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam15 ADAM metallopeptidase domain 15 involved_in ISO (PMID:22505472) RGD PMID:22505472 NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113 		JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:10359807) RGD PMID:10359807 NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930 		JBrowse link
G Prf1 perforin 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:66009|PMID:8164737)		 UniProt
Ensembl
RGD		 PMID:8164737 GO_REF:0000024 GO_REF:0000107 MGI:66009 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701 		JBrowse link
natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkg7 natural killer cell granule protein 7 involved_in ISO (MGI:6506882|PMID:32839608) RGD PMID:32839608 MGI:6506882 NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983 		JBrowse link
negative regulation of immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) RGD PMID:22842346 MGI:5437532 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS		 (PMID:23696226)
(MGI:5512785|PMID:23696226)
GO_REF:0000024		 RGD
UniProt		 PMID:23696226 GO_REF:0000024 MGI:5512785 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) RGD PMID:22842346 MGI:5437532 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Klre1 killer cell lectin like receptor E1 IDA RGD PMID:12782717 RGD:1299590 NCBI chr 4:163,033,581...163,041,641
Ensembl chr 4:163,033,563...163,041,638 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:24586048) RGD PMID:24586048 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc4 mucin 4, cell surface associated IDA RGD PMID:10232613 RGD:2303754 NCBI chr11:68,008,245...68,053,242 JBrowse link
negative regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor involved_in ISO
ISS
IEA		 (PMID:32818467)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:32818467 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:28813410), (PMID:28813417) RGD PMID:28813410 PMID:28813417 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:32818467)
(MGI:6508501|PMID:21469114), (MGI:6508513|PMID:28405502)		 RGD PMID:21469114 PMID:28405502 PMID:32818467 MGI:6508501 MGI:6508513 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Pdcd1 programmed cell death 1 involved_in ISO (PMID:38377992) RGD PMID:38377992 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISO
ISS		 (PMID:38377992)
GO_REF:0000024		 RGD
UniProt		 PMID:38377992 GO_REF:0000024 NCBI chr 5:38,962,721...38,995,134
Ensembl chr 5:38,962,171...38,995,199 		JBrowse link
positive regulation of immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40lg CD40 ligand IDA RGD PMID:19016771 RGD:2313413 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Gsdme gasdermin E involved_in ISO (PMID:32188940) RGD PMID:32188940 NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806 		JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISS
ISO		 GO_REF:0000024
(MGI:5427055|PMID:22348394)
(PMID:21215706)		 UniProt
RGD		 PMID:21215706 PMID:22348394 GO_REF:0000024 MGI:5427055 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389 		JBrowse link
G Hrg l1 histidine-rich glycoprotein like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353 		JBrowse link
G Ulbp1 UL16 binding protein 1 acts_upstream_of_or_within ISO (PMID:12645935) RGD PMID:12645935 NCBI chr 1:1,694,255...1,716,160 JBrowse link
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in ISO
IBA		 (PMID:12913096)
GO_REF:0000033		 RGD
GO_Central		 PMID:12913096 GO_REF:0000033 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO
IBA		 (PMID:15811952)
GO_REF:0000033
(MGI:3689781|PMID:15811952)		 RGD
GO_Central		 PMID:15811952 GO_REF:0000033 MGI:3689781 NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343 		JBrowse link
G Il12a interleukin 12A involved_in ISO
IEA		 (PMID:7903063)
GO_REF:0000107		 RGD
Ensembl		 PMID:7903063 GO_REF:0000107 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:7903063) RGD PMID:7903063 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Klrk1 killer cell lectin like receptor K1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IBA		 (PMID:12913096)
GO_REF:0000033		 RGD
GO_Central		 PMID:12913096 GO_REF:0000033 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715 		JBrowse link
G Raet1ll1 retinoic acid early transcript 1L like 1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 1:1,397,219...1,437,802
Ensembl chr 1:1,397,230...1,402,656 		JBrowse link
positive regulation of natural killer cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd160 CD160 molecule involved_in ISO (MGI:5644003|PMID:25711213) RGD PMID:25711213 MGI:5644003 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mr1 major histocompatibility complex, class I-related involved_in ISO
IEA		 (PMID:31959982)
GO_REF:0000107		 RGD
Ensembl		 PMID:31959982 GO_REF:0000107 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970 		JBrowse link
G Slc22a13 solute carrier family 22 member 13 involved_in ISO (PMID:19282870) RGD PMID:19282870 NCBI chr 8:118,922,367...118,934,020
Ensembl chr 8:118,922,367...118,953,635 		JBrowse link
positive regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule acts_upstream_of_or_within ISO (PMID:7774619) RGD PMID:7774619 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Fbxo38 F-box protein 38 involved_in ISO (PMID:30487606) RGD PMID:30487606 NCBI chr18:55,956,950...56,004,013
Ensembl chr18:55,956,959...56,003,961 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:10663613) RGD PMID:10663613 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:30282837) RGD PMID:30282837 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
regulation of response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dapk1 death associated protein kinase 1 involved_in ISO (PMID:11573098) RGD PMID:11573098 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5470371|PMID:23108142)		 UniProt
RGD		 PMID:23108142 GO_REF:0000024 MGI:5470371 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:1402688), (PMID:17189421), (PMID:20364150) RGD PMID:1402688 PMID:17189421 PMID:20364150 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    response to stimulus 10920
      response to biotic stimulus 1898
        response to tumor cell 52
          cellular response to tumor cell 4
          defense response to tumor cell 12
          detection of tumor cell 1
          immune response to tumor cell + 36
          negative regulation of response to tumor cell + 10
          positive regulation of response to tumor cell + 20
          regulation of response to tumor cell + 32
paths to the root