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ONTOLOGY REPORT - ANNOTATIONS

Term:response to tumor cell
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Accession:GO:0002347 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.


show annotations for term's descendants           Sort by:
response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnmt histamine N-methyltransferase IEP RGD PMID:3111198 RGD:2316837 NCBI chr 3:26,978,274...27,010,291
Ensembl chr 3:6,591,463...6,624,012 		JBrowse link
G Kctd9 potassium channel tetramerization domain containing 9 acts_upstream_of_or_within ISO (PMID:31024568) RGD PMID:31024568 NCBI chr15:46,117,211...46,145,258
Ensembl chr15:41,942,381...41,969,862 		JBrowse link
cellular response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igfbpl1 insulin-like growth factor binding protein-like 1 involved_in ISO (PMID:15845387) RGD PMID:15845387 NCBI chr 5:64,872,056...64,887,461
Ensembl chr 5:60,076,429...60,091,833 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO
IEA		 (PMID:11306509)
GO_REF:0000107		 RGD
Ensembl		 PMID:11306509 GO_REF:0000107 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Notch2 notch receptor 2 involved_in ISO
IEA
ISS		 (PMID:11306509)
GO_REF:0000107
GO_REF:0000024
GO_REF:0000002		 RGD
Ensembl
UniProt
InterPro		 PMID:11306509 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:188,299,336...188,432,823
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Txnip thioredoxin interacting protein involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:18541147)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18541147 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
defense response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi3 ABI family, member 3 involved_in ISO
IEA		 (PMID:21223585)
GO_REF:0000107		 RGD
Ensembl		 PMID:21223585 GO_REF:0000107 NCBI chr10:81,266,571...81,277,561
Ensembl chr10:80,769,822...80,780,816 		JBrowse link
G Abi3bp ABI family member 3 binding protein involved_in ISS GO_REF:0000024 ARUK-UCL GO_REF:0000024 NCBI chr11:57,381,282...57,597,989
Ensembl chr11:43,913,043...44,128,929 		JBrowse link
G Dapk1 death associated protein kinase 1 involved_in ISO (PMID:30429596) RGD PMID:30429596 NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Dlec1 DLEC1 cilia and flagella associated protein involved_in ISO
IEA		 (PMID:30429596)
GO_REF:0000107		 RGD
Ensembl		 PMID:30429596 GO_REF:0000107 NCBI chr 8:127,704,181...127,750,929
Ensembl chr 8:118,826,466...118,873,655 		JBrowse link
G Klf4 KLF transcription factor 4 involved_in ISO
IEA		 (PMID:30429596)
GO_REF:0000107		 RGD
Ensembl		 PMID:30429596 GO_REF:0000107 NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:19787053) RGD PMID:19787053 NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Plk5 polo-like kinase 5 involved_in ISO (PMID:21245385) RGD PMID:21245385 NCBI chr 7:9,997,453...10,006,959
Ensembl chr 7:9,346,777...9,355,196 		JBrowse link
G Prdx2 peroxiredoxin 2 involved_in ISO (PMID:30429596) RGD PMID:30429596 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Prf1 perforin 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:8164737)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:8164737 GO_REF:0000024 GO_REF:0000107 NCBI chr20:29,789,040...29,794,550
Ensembl chr20:29,246,202...29,251,701 		JBrowse link
G Rbms3 RNA binding motif, single stranded interacting protein 3 involved_in ISO
IEA		 (PMID:28409548)
GO_REF:0000107		 RGD
Ensembl		 PMID:28409548 GO_REF:0000107 NCBI chr 8:125,183,311...125,970,239
Ensembl chr 8:116,309,882...117,625,423 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO
IEA		 (PMID:28362429)
GO_REF:0000107		 RGD
Ensembl		 PMID:28362429 GO_REF:0000107 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO
IEA		 (PMID:28362429), (PMID:28481873), (PMID:30429596)
GO_REF:0000107		 RGD
Ensembl		 PMID:28362429 PMID:28481873 PMID:30429596 GO_REF:0000107 NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
detection of tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO
IEA
IBA		 (PMID:15811952)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:15811952 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:50,237,210...50,274,472
Ensembl chr 8:41,340,837...41,377,343 		JBrowse link
immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam15 ADAM metallopeptidase domain 15 involved_in ISO
IEA		 (PMID:22505472)
GO_REF:0000107		 RGD
Ensembl		 PMID:22505472 GO_REF:0000107 NCBI chr 2:177,052,363...177,062,879
Ensembl chr 2:174,754,633...174,765,113 		JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:10359807) RGD PMID:10359807 NCBI chr 1:87,500,591...87,526,983
Ensembl chr 1:78,372,802...78,398,930 		JBrowse link
G Prf1 perforin 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:8164737)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:8164737 GO_REF:0000024 GO_REF:0000107 NCBI chr20:29,789,040...29,794,550
Ensembl chr20:29,246,202...29,251,701 		JBrowse link
natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkg7 natural killer cell granule protein 7 involved_in ISO (PMID:32839608) RGD PMID:32839608 NCBI chr 1:102,981,497...102,982,564
Ensembl chr 1:93,844,902...93,845,983 		JBrowse link
negative regulation of immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) RGD PMID:22842346 NCBI chr10:31,383,801...31,415,334
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS		 (PMID:23696226)
GO_REF:0000024		 RGD
UniProt		 PMID:23696226 GO_REF:0000024 NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) RGD PMID:22842346 NCBI chr10:31,383,801...31,415,334
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Klre1 killer cell lectin like receptor E1 IDA RGD PMID:12782717 RGD:1299590 NCBI chr 4:164,719,307...164,727,664
Ensembl chr 4:163,033,563...163,041,638 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
IEA		 (PMID:24586048)
GO_REF:0000107		 RGD
Ensembl		 PMID:24586048 GO_REF:0000107 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc4 mucin 4, cell surface associated IDA RGD PMID:10232613 RGD:2303754 NCBI chr11:81,513,321...81,575,200 JBrowse link
negative regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor involved_in ISO
ISS		 (PMID:32818467)
GO_REF:0000024		 RGD
UniProt		 PMID:32818467 GO_REF:0000024 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:28813410), (PMID:28813417) RGD PMID:28813410 PMID:28813417 NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:32818467)
(PMID:21469114), (PMID:28405502)		 RGD PMID:21469114 PMID:28405502 PMID:32818467 NCBI chr 1:104,435,540...104,461,049
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:37208329) RGD PMID:37208329 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Pdcd1 programmed cell death 1 involved_in ISO (PMID:38377992) RGD PMID:38377992 NCBI chr 9:101,866,124...101,879,278
Ensembl chr 9:94,418,791...94,431,937 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISO
IEA
ISS		 (PMID:38377992)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:38377992 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:43,759,271...43,791,682
Ensembl chr 5:38,962,171...38,995,199 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 involved_in ISO (PMID:37208329) RGD PMID:37208329 NCBI chr 4:159,305,927...159,321,345
Ensembl chr 4:157,619,643...157,634,711 		JBrowse link
positive regulation of immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40lg CD40 ligand IDA RGD PMID:19016771 RGD:2313413 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Gsdme gasdermin E involved_in ISO
IEA		 (PMID:32188940)
GO_REF:0000107		 RGD
Ensembl		 PMID:32188940 GO_REF:0000107 NCBI chr 4:80,590,344...80,651,943
Ensembl chr 4:79,257,804...79,320,806 		JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:22348394)
(PMID:21215706)		 UniProt
GO_Central
RGD		 PMID:21215706 PMID:22348394 GO_REF:0000024 GO_REF:0000033 NCBI chr11:91,559,087...91,573,982
Ensembl chr11:78,054,498...78,069,389 		JBrowse link
G Hrgl1 histidine-rich glycoprotein like 1 involved_in ISS
IBA		 GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr11:91,543,964...91,553,946
Ensembl chr11:78,039,376...78,049,353 		JBrowse link
G Ulbp1 UL16 binding protein 1 acts_upstream_of_or_within ISO (PMID:12645935) RGD PMID:12645935 NCBI chr 1:3,506,106...3,527,982 JBrowse link
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in ISO
IEA		 (PMID:12913096)
GO_REF:0000107		 RGD
Ensembl		 PMID:12913096 GO_REF:0000107 NCBI chr18:84,723,330...84,819,836
Ensembl chr18:82,450,568...82,543,051 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO
IEA
IBA		 (PMID:15811952)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:15811952 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:50,237,210...50,274,472
Ensembl chr 8:41,340,837...41,377,343 		JBrowse link
G Il12a interleukin 12A involved_in ISO
IEA		 (PMID:7903063)
GO_REF:0000107		 RGD
Ensembl		 PMID:7903063 GO_REF:0000107 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B involved_in ISO
IEA		 (PMID:7903063)
GO_REF:0000107		 RGD
Ensembl		 PMID:7903063 GO_REF:0000107 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Klrk1 killer cell lectin like receptor K1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 4:164,767,377...164,778,453
Ensembl chr 4:163,081,927...163,092,459 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IEA
IBA		 (PMID:12913096)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:12913096 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:88,500,086...88,535,474
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr 1:88,689,235...88,704,641
Ensembl chr 1:79,546,879...79,576,715 		JBrowse link
G Raet1ll1 retinoic acid early transcript 1L like 1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 1:3,206,980...3,249,638
Ensembl chr 1:1,397,230...1,402,656 		JBrowse link
positive regulation of natural killer cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd160 CD160 molecule involved_in ISO
IEA		 (PMID:25711213)
GO_REF:0000107		 RGD
Ensembl		 PMID:25711213 GO_REF:0000107 NCBI chr 2:187,029,654...187,042,447
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mr1 major histocompatibility complex, class I-related involved_in ISO
IEA		 (PMID:31959982)
GO_REF:0000107		 RGD
Ensembl		 PMID:31959982 GO_REF:0000107 NCBI chr13:69,850,420...69,868,302
Ensembl chr13:67,299,585...67,317,970 		JBrowse link
G Slc22a13 solute carrier family 22 member 13 involved_in ISO (PMID:19282870) RGD PMID:19282870 NCBI chr 8:127,800,097...127,811,750
Ensembl chr 8:118,922,367...118,953,635 		JBrowse link
positive regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule acts_upstream_of_or_within ISO (PMID:7774619) RGD PMID:7774619 NCBI chr20:48,655,549...48,661,786
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Fbxo38 F-box protein 38 involved_in ISO
IEA		 (PMID:30487606)
GO_REF:0000107		 RGD
Ensembl		 PMID:30487606 GO_REF:0000107 NCBI chr18:58,227,253...58,274,320
Ensembl chr18:55,956,959...56,003,961 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:10663613) RGD PMID:10663613 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Klhl22 kelch-like family member 22 involved_in ISO (PMID:33109719) RGD PMID:33109719 NCBI chr11:96,695,168...96,736,079
Ensembl chr11:83,190,891...83,231,770 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in ISO
IEA		 (PMID:38377992)
GO_REF:0000107		 RGD
Ensembl		 PMID:38377992 GO_REF:0000107 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:30282837) RGD PMID:30282837 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma involved_in ISO
IEA		 (PMID:38377992)
GO_REF:0000107		 RGD
Ensembl		 PMID:38377992 GO_REF:0000107 NCBI chr12:26,381,106...26,409,466
Ensembl chr12:20,744,535...20,772,827 		JBrowse link
regulation of response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dapk1 death associated protein kinase 1 involved_in ISO (PMID:11573098) RGD PMID:11573098 NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23108142)		 UniProt
RGD		 PMID:23108142 GO_REF:0000024 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:1402688), (PMID:17189421), (PMID:20364150) RGD PMID:1402688 PMID:17189421 PMID:20364150 NCBI chr20:3,261,656...3,265,548
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      response to biotic stimulus 1943
        response to tumor cell 58
          cellular response to tumor cell 4
          defense response to tumor cell 12
          detection of tumor cell 1
          immune response to tumor cell + 41
          negative regulation of response to tumor cell + 12
          positive regulation of response to tumor cell + 23
          regulation of response to tumor cell + 37
paths to the root