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ONTOLOGY REPORT - ANNOTATIONS

Term:B-1a B cell differentiation
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Accession:GO:0002337 term browser browse the term
Definition:The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: B-1a B lymphocyte differentiation
 related_synonym: B-1a B cell development


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B-1a B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmtm7 CKLF-like MARVEL transmembrane domain containing 7 acts_upstream_of_or_within ISO (PMID:24080084) RGD PMID:24080084 NCBI chr 8:114,448,037...114,474,958
Ensembl chr 8:114,448,042...114,474,621 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 IMP RGD PMID:19327106 RGD:41408336 NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:2181762 (PMID:14595020) RGD PMID:14595020 NCBI chr18:76,321,386...76,430,997
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Plcl2 phospholipase C-like 2 acts_upstream_of_or_within ISO
IEA		 MGI:2679632 (PMID:14517301)
GO_REF:0000107		 RGD
Ensembl		 PMID:14517301 GO_REF:0000107 NCBI chr 9:3,529,117...3,713,712
Ensembl chr 9:3,292,695...3,477,009 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    immune system process 3130
      leukocyte activation 1082
        lymphocyte activation 875
          lymphocyte differentiation 453
            B cell differentiation 158
              mature B cell differentiation 45
                B-1 B cell differentiation 7
                  B-1a B cell differentiation 4
Path 2
Term Annotations click to browse term
  biological_process 20558
    developmental process 7149
      cellular developmental process 4833
        cell differentiation 4832
          cell development 3350
            hemopoiesis 1083
              leukocyte differentiation 690
                mononuclear cell differentiation 556
                  lymphocyte differentiation 453
                    B cell differentiation 158
                      mature B cell differentiation 45
                        B-1 B cell differentiation 7
                          B-1a B cell differentiation 4
paths to the root