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ONTOLOGY REPORT - ANNOTATIONS

Term:immature B cell differentiation
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Accession:GO:0002327 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of an immature B cell.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: immature B lymphocyte differentiation
 related_synonym: immature B cell development

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immature B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fnip1 folliculin interacting protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:22608497) Ensembl
MGI
UniProt		 PMID:22608497 GO_REF:0000024 GO_REF:0000107 NCBI chrNW_004936647:3,329,097...3,428,170
Ensembl chrNW_004936647:3,329,103...3,428,242 		JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936484:17,653,519...17,661,811
Ensembl chrNW_004936484:17,655,241...17,659,553 		JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936482:17,162,854...17,238,319
Ensembl chrNW_004936482:17,162,950...17,238,274 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9768755) Ensembl
MGI		 PMID:9768755 GO_REF:0000107 NCBI chrNW_004936590:4,722,914...4,887,615
Ensembl chrNW_004936590:4,722,873...4,890,156 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:5926569|PMID:28062693) ARUK-UCL PMID:28062693 MGI:5926569 NCBI chrNW_004936562:1,852,759...1,870,647
Ensembl chrNW_004936562:1,852,740...1,870,472 		JBrowse link
G Syvn1 synoviolin 1 involved_in ISO (MGI:6220623|PMID:29907570) UniProt PMID:29907570 MGI:6220623 NCBI chrNW_004936599:4,235,779...4,243,395
Ensembl chrNW_004936599:4,236,188...4,243,394 		JBrowse link
negative regulation of pre-B cell receptor expression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:5444793|PMID:22949502) ARUK-UCL PMID:22949502 MGI:5444793 NCBI chrNW_004936474:14,102,080...14,119,592
Ensembl chrNW_004936474:14,102,423...14,119,558 		JBrowse link
pre-B cell allelic exclusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936551:359,134...534,672
Ensembl chrNW_004936551:359,362...532,211 		JBrowse link
G Rag1 recombination activating 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936533:1,817,135...1,827,393
Ensembl chrNW_004936533:1,817,135...1,827,393 		JBrowse link
G Rag2 recombination activating 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936533:1,801,207...1,807,431
Ensembl chrNW_004936533:1,801,391...1,807,431 		JBrowse link
pre-B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp11c ATPase phospholipid transporting 11C involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936513:7,701,733...7,889,753
Ensembl chrNW_004936513:7,701,725...7,889,750 		JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:16819554) MGI PMID:16819554 NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324 		JBrowse link
G LOC101968601 signal transducer CD24 acts_upstream_of_or_within ISO (PMID:7795661), (PMID:9028339) MGI PMID:7795661 PMID:9028339 NCBI chrNW_004936491:16,706,745...16,707,010 JBrowse link
G Lrrc8a leucine rich repeat containing 8 VRAC subunit A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:16,360,672...16,387,860
Ensembl chrNW_004936487:16,361,014...16,389,380 		JBrowse link
transitional one stage B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19228876) Ensembl
MGI		 PMID:19228876 GO_REF:0000107 NCBI chrNW_004936487:17,690,206...17,819,619
Ensembl chrNW_004936487:17,690,968...17,819,669 		JBrowse link
G Tnfsf13b TNF superfamily member 13b involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17581616) Ensembl
MGI		 PMID:17581616 GO_REF:0000107 NCBI chrNW_004936472:3,789,111...3,834,163
Ensembl chrNW_004936472:3,788,095...3,822,148 		JBrowse link
transitional two stage B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Traf3ip2 TRAF3 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936679:308,508...348,561
Ensembl chrNW_004936679:316,277...336,557 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15871
    immune system process 2193
      leukocyte activation 918
        lymphocyte activation 748
          lymphocyte differentiation 402
            B cell differentiation 139
              immature B cell differentiation 17
                pre-B cell differentiation + 8
                transitional stage B cell differentiation + 3
Path 2
Term Annotations click to browse term
  biological_process 15871
    developmental process 6321
      cellular developmental process 4251
        cell differentiation 4250
          cell development 3049
            hemopoiesis 956
              leukocyte differentiation 607
                mononuclear cell differentiation 491
                  lymphocyte differentiation 402
                    B cell differentiation 139
                      immature B cell differentiation 17
                        pre-B cell differentiation + 8
                        transitional stage B cell differentiation + 3
paths to the root