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ONTOLOGY REPORT - ANNOTATIONS

Term:natural killer cell activation involved in immune response
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Accession:GO:0002323 term browser browse the term
Definition:The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
Synonyms:related_synonym: NK cell activation during immune response;   natural killer cell activation during immune response


show annotations for term's descendants           Sort by:
natural killer cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (PMID:11714776)
(PMID:15905190)
(MGI:3773416|PMID:15905190)		 RGD PMID:11714776 PMID:15905190 MGI:3773416 NCBI chr13:84,051,339...84,082,864
Ensembl chr13:84,052,493...84,074,492 		JBrowse link
G Cd244l1 CD244 molecule like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:84,018,887...84,036,612
Ensembl chr13:84,020,095...84,036,100 		JBrowse link
G Ifna1 interferon, alpha 1 acts_upstream_of_or_within ISO (PMID:19130550) RGD PMID:19130550 NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925 		JBrowse link
G Ifna12l interferon alpha 12 like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,476,362...103,477,427
Ensembl chr 5:103,476,657...103,477,211
Ensembl chr 5:103,476,657...103,477,211
Ensembl chr 5:103,476,657...103,477,211 		JBrowse link
G Ifna4 interferon, alpha 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,069,174...103,070,120
Ensembl chr 5:103,069,483...103,070,052 		JBrowse link
G Ifna5 interferon, alpha 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,187,852...103,188,430 JBrowse link
G Ifnb1 interferon beta 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifne interferon, epsilon involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,571,630...103,572,290
Ensembl chr 5:103,569,675...103,572,256 		JBrowse link
G Ifnk interferon kappa involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:49,732,073...49,734,281
Ensembl chr 5:49,732,073...49,734,281 		JBrowse link
G Il12b interleukin 12B IMP RGD PMID:14960310 RGD:1600048 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G LOC120103163 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,494,442...103,495,077
Ensembl chr 5:103,494,448...103,495,002 		JBrowse link
G LOC120103164 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,509,610...103,510,260
Ensembl chr 5:103,509,616...103,510,170 		JBrowse link
natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin 1A involved_in ISO (PMID:24760828) RGD PMID:24760828 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534 		JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO (PMID:25786175), (PMID:28652325) RGD PMID:25786175 PMID:28652325 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921 		JBrowse link
G Nkg7 natural killer cell granule protein 7 involved_in ISO (MGI:6506882|PMID:32839608), (MGI:6810811|PMID:33911019) RGD PMID:32839608 PMID:33911019 MGI:6506882 MGI:6810811 NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983 		JBrowse link
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within ISO MGI:1856656 (PMID:11266473) RGD PMID:11266473 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829 		JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (PMID:23042080), (PMID:23190531) RGD PMID:23042080 PMID:23190531 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164 		JBrowse link
G Unc13d unc-13 homolog D involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3628822 (PMID:17420270)		 Ensembl
RGD		 PMID:17420270 GO_REF:0000107 NCBI chr10:101,296,755...101,311,513
Ensembl chr10:101,296,776...101,311,687 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 NOT|involved_in ISO (PMID:18042464) RGD PMID:18042464 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809 		JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in ISO (PMID:18042464) RGD PMID:18042464 NCBI chr12:16,728,486...16,764,261
Ensembl chr12:16,728,524...16,764,097 		JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (MGI:5491117|PMID:23408620)
(PMID:23408620)		 RGD PMID:23408620 MGI:5491117 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
negative regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pglyrp1 peptidoglycan recognition protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2670590 (PMID:20709292)		 Ensembl
RGD		 PMID:20709292 GO_REF:0000107 NCBI chr 1:78,531,815...78,537,001
Ensembl chr 1:78,531,815...78,537,001 		JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 acts_upstream_of_or_within ISO MGI:5297105 (PMID:20709292) RGD PMID:20709292 NCBI chr 7:11,418,674...11,432,162
Ensembl chr 7:11,418,880...11,427,773 		JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 acts_upstream_of_or_within ISO MGI:5297106 (PMID:20709292) RGD PMID:20709292 NCBI chr 2:177,479,693...177,490,769
Ensembl chr 2:177,477,407...177,490,736
Ensembl chr 2:177,477,407...177,490,736 		JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 acts_upstream_of_or_within ISO MGI:5297107 (PMID:20709292) RGD PMID:20709292 NCBI chr 2:176,202,654...176,322,859
Ensembl chr 2:176,218,519...176,242,251 		JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr19:37,744,633...37,831,134
Ensembl chr19:37,744,633...37,829,167 		JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:19109136) RGD PMID:19109136 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:21825173) RGD PMID:21825173 NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO
IEA		 (PMID:23632890)
GO_REF:0000107		 RGD
Ensembl		 PMID:23632890 GO_REF:0000107 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:3,403,418...3,479,476 JBrowse link
regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zfp683 zinc finger protein 683 involved_in ISO (MGI:5437828|PMID:22885984) RGD PMID:22885984 MGI:5437828 NCBI chr 5:146,277,972...146,285,856
Ensembl chr 5:146,278,978...146,285,000 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20133
    immune system process 2856
      leukocyte activation 1049
        leukocyte activation involved in immune response 326
          lymphocyte activation involved in immune response 227
            natural killer cell activation involved in immune response 31
              natural killer cell degranulation + 14
              natural killer cell differentiation involved in immune response + 5
              natural killer cell proliferation involved in immune response + 0
Path 2
Term Annotations click to browse term
  biological_process 20133
    cellular process 19325
      cell activation 1203
        cell activation involved in immune response 330
          leukocyte activation involved in immune response 326
            lymphocyte activation involved in immune response 227
              natural killer cell activation involved in immune response 31
                natural killer cell degranulation + 14
                natural killer cell differentiation involved in immune response + 5
                natural killer cell proliferation involved in immune response + 0
paths to the root