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ONTOLOGY REPORT - ANNOTATIONS

Term:mature B cell differentiation involved in immune response
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Accession:GO:0002313 term browser browse the term
Definition:The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:related_synonym: mature B cell development involved in immune response;   mature B-cell differentiation during immune response;   mature B-lymphocyte differentiation during immune response

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mature B cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CUNH17orf99 chromosome unknown C17orf99 homolog involved_in ISO (MGI:6103709|PMID:28978694) UniProt PMID:28978694 MGI:6103709 NCBI chrNW_004955506:4,397,221...4,408,645 JBrowse link
G Gpr183 G protein-coupled receptor 183 involved_in ISO (MGI:4352759|PMID:19597478) UniProt PMID:19597478 MGI:4352759 NCBI chrNW_004955404:11,264,954...11,277,531
Ensembl chrNW_004955404:11,264,954...11,277,531 		JBrowse link
G Rag2 recombination activating 2 ISO RGD PMID:30206106 RGD:38508903 NCBI chrNW_004955422:9,867,307...9,869,732
Ensembl chrNW_004955422:9,867,307...9,869,732 		JBrowse link
follicular B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf8 interferon regulatory factor 8 involved_in ISO (MGI:6303891|PMID:31000603) ARUK-UCL PMID:31000603 MGI:6303891 NCBI chrNW_004955541:973,004...988,493
Ensembl chrNW_004955541:973,022...990,106 		JBrowse link
G Plcg2 phospholipase C gamma 2 acts_upstream_of_or_within ISO (PMID:12928432) MGI PMID:12928432 NCBI chrNW_004955522:4,352,890...4,480,735
Ensembl chrNW_004955522:4,358,233...4,468,986 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:6303891|PMID:31000603) ARUK-UCL PMID:31000603 MGI:6303891 NCBI chrNW_004955422:873,735...886,560
Ensembl chrNW_004955422:873,735...886,560 		JBrowse link
germinal center B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (PMID:14607964) MGI PMID:14607964 NCBI chrNW_004955445:12,696,096...12,717,488
Ensembl chrNW_004955445:12,696,096...12,717,488 		JBrowse link
G Cdh17 cadherin 17 involved_in ISO (MGI:3531365|PMID:15688343) UniProt PMID:15688343 MGI:3531365 NCBI chrNW_004955417:10,370,606...10,441,008
Ensembl chrNW_004955417:10,370,471...10,441,128 		JBrowse link
G Il21 interleukin 21 involved_in ISO (MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:5450752 NCBI chrNW_004955428:18,057,096...18,065,492
Ensembl chrNW_004955428:18,057,096...18,065,492 		JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:5450752 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Irf8 interferon regulatory factor 8 involved_in ISO (MGI:6303891|PMID:31000603) ARUK-UCL PMID:31000603 MGI:6303891 NCBI chrNW_004955541:973,004...988,493
Ensembl chrNW_004955541:973,022...990,106 		JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 acts_upstream_of_or_within ISO (PMID:23997217) MGI PMID:23997217 NCBI chrNW_004955429:18,356,642...18,372,928
Ensembl chrNW_004955429:18,356,642...18,372,928 		JBrowse link
G Phf14 PHD finger protein 14 involved_in ISO (MGI:6514486|PMID:33035772) UniProt PMID:33035772 MGI:6514486 NCBI chrNW_004955432:17,535,222...17,807,106
Ensembl chrNW_004955432:17,535,224...17,697,936 		JBrowse link
G Pou2af1 POU class 2 homeobox associating factor 1 involved_in ISO (MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:5450752 NCBI chrNW_004955412:13,131,229...13,167,150
Ensembl chrNW_004955412:13,131,168...13,156,128 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:6303891|PMID:31000603) ARUK-UCL PMID:31000603 MGI:6303891 NCBI chrNW_004955422:873,735...886,560
Ensembl chrNW_004955422:873,735...886,560 		JBrowse link
marginal zone B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl3 BCL3 transcription coactivator acts_upstream_of_or_within ISO (PMID:9009202) MGI PMID:9009202 NCBI chrNW_004955555:1,898,280...1,911,466
Ensembl chrNW_004955555:1,856,250...1,911,466 		JBrowse link
G Cdh17 cadherin 17 involved_in ISO (MGI:3531365|PMID:15688343) UniProt PMID:15688343 MGI:3531365 NCBI chrNW_004955417:10,370,606...10,441,008
Ensembl chrNW_004955417:10,370,471...10,441,128 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in ISO (MGI:3044313|PMID:15146182), (MGI:3838059|PMID:19217325) UniProt PMID:15146182 PMID:19217325 MGI:3044313 MGI:3838059 NCBI chrNW_004955411:3,478,943...3,486,541
Ensembl chrNW_004955411:3,478,033...3,486,604 		JBrowse link
G Dock10 dedicator of cytokinesis 10 involved_in ISO (MGI:5818419|PMID:25729399) UniProt PMID:25729399 MGI:5818419 NCBI chrNW_004955453:9,229,535...9,424,570
Ensembl chrNW_004955453:9,264,666...9,424,570 		JBrowse link
G Dock11 dedicator of cytokinesis 11 involved_in ISO (MGI:5818419|PMID:25729399) UniProt PMID:25729399 MGI:5818419 NCBI chrNW_004955534:1,239,241...1,431,714
Ensembl chrNW_004955534:1,239,247...1,431,714 		JBrowse link
G Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in ISO (MGI:3838059|PMID:19217325) UniProt PMID:19217325 MGI:3838059 NCBI chrNW_004955460:12,773,975...12,784,512
Ensembl chrNW_004955460:12,773,975...12,784,512 		JBrowse link
G Mfng MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in ISO (MGI:3838059|PMID:19217325) UniProt PMID:19217325 MGI:3838059 NCBI chrNW_004955413:23,901,987...23,917,720
Ensembl chrNW_004955413:23,902,707...23,917,542 		JBrowse link
G Notch2 notch receptor 2 involved_in ISO (MGI:3838059|PMID:19217325) UniProt PMID:19217325 MGI:3838059 NCBI chrNW_004955568:1,660,357...1,812,285
Ensembl chrNW_004955568:1,660,731...1,809,173 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISO (MGI:1860716|PMID:10881171) UniProt PMID:10881171 MGI:1860716 NCBI chrNW_004955403:49,856,056...49,970,800
Ensembl chrNW_004955403:49,855,541...49,973,225 		JBrowse link
memory B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO (MGI:2387354|PMID:10755614) UniProt PMID:10755614 MGI:2387354 NCBI chrNW_004955461:7,960,901...8,036,221
Ensembl chrNW_004955461:7,960,690...7,976,183 		JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within ISO (PMID:15240705) MGI PMID:15240705 NCBI chrNW_004955420:19,998,960...20,021,200
Ensembl chrNW_004955420:19,998,742...20,022,259 		JBrowse link
plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of ISO (PMID:15240705) MGI PMID:15240705 NCBI chrNW_004955420:19,998,960...20,021,200
Ensembl chrNW_004955420:19,998,742...20,022,259 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:29259245) MGI PMID:29259245 NCBI chrNW_004955436:12,416,147...12,477,214
Ensembl chrNW_004955436:12,415,737...12,480,359 		JBrowse link
G Itm2a integral membrane protein 2A acts_upstream_of_or_within ISO (PMID:24831988) MGI PMID:24831988 NCBI chrNW_004955557:2,235,223...2,243,911
Ensembl chrNW_004955557:2,235,223...2,243,927 		JBrowse link
G Lgals1 galectin 1 acts_upstream_of_or_within ISO (PMID:21753146) MGI PMID:21753146 NCBI chrNW_004955413:24,072,086...24,075,452
Ensembl chrNW_004955413:24,072,086...24,075,452 		JBrowse link
G Lgals8 galectin 8 acts_upstream_of_or_within ISO (PMID:21753146) MGI PMID:21753146 NCBI chrNW_004955492:3,673,233...3,693,777
Ensembl chrNW_004955492:3,673,233...3,693,776 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:25124037) MGI PMID:25124037 NCBI chrNW_004955427:3,350,174...3,358,609
Ensembl chrNW_004955427:3,350,174...3,360,379 		JBrowse link
G Nkx2-3 NK2 homeobox 3 acts_upstream_of_or_within ISO (PMID:10926756) MGI PMID:10926756 NCBI chrNW_004955507:5,454,871...5,457,247
Ensembl chrNW_004955507:5,455,087...5,457,660 		JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 acts_upstream_of ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779 		JBrowse link
G Il2 interleukin 2 acts_upstream_of ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:11460154) UniProt PMID:11460154 NCBI chrNW_004955455:3,037,885...3,041,827 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    immune system process 1980
      leukocyte activation 888
        lymphocyte activation 720
          B cell activation 255
            B cell activation involved in immune response 89
              mature B cell differentiation involved in immune response 32
                follicular B cell differentiation 3
                germinal center B cell differentiation 9
                marginal zone B cell differentiation 9
                memory B cell differentiation 1
                plasma cell differentiation + 10
Path 2
Term Annotations click to browse term
  biological_process 12346
    cellular process 11480
      cellular developmental process 3877
        cell differentiation 3876
          cell development 2836
            hemopoiesis 919
              leukocyte differentiation 591
                mononuclear cell differentiation 482
                  lymphocyte differentiation 394
                    B cell differentiation 135
                      mature B cell differentiation 41
                        mature B cell differentiation involved in immune response 32
                          follicular B cell differentiation 3
                          germinal center B cell differentiation 9
                          marginal zone B cell differentiation 9
                          memory B cell differentiation 1
                          plasma cell differentiation + 10
paths to the root