The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
Comment:
Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:
exact_synonym:
CD4-positive, gamma-delta intraepithelial T lymphocyte differentiation
related_synonym:
CD4-positive, gamma-delta intraepithelial T cell development