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ONTOLOGY REPORT - ANNOTATIONS


Term:CD8-positive, gamma-delta intraepithelial T cell differentiation
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Accession:GO:0002305 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: CD8-positive, gamma-delta intraepithelial T-lymphocyte differentiation
 related_synonym: CD8-positive, gamma-delta intraepithelial T cell development


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CD8-positive, gamma-delta intraepithelial T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr9 C-C motif chemokine receptor 9 acts_upstream_of_or_within ISO (MGI:5629467|PMID:25348153) MGI PMID:25348153 MGI:5629467 NCBI chrNW_004936695:55,788...59,251 JBrowse link
G Gpr18 G protein-coupled receptor 18 acts_upstream_of_or_within ISO (MGI:5629467|PMID:25348153) MGI PMID:25348153 MGI:5629467 NCBI chrNW_004936472:11,240,287...11,242,157 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12164
    immune system process 2052
      leukocyte activation 817
        lymphocyte activation 661
          T cell activation 457
            T cell differentiation 265
              gamma-delta T cell differentiation 12
                gamma-delta intraepithelial T cell differentiation 2
                  CD8-positive, gamma-delta intraepithelial T cell differentiation 2
Path 2
Term Annotations click to browse term
  biological_process 12164
    developmental process 5729
      anatomical structure development 5357
        multicellular organism development 4905
          system development 4621
            immune system development 961
              hematopoietic or lymphoid organ development 899
                hemopoiesis 852
                  leukocyte differentiation 532
                    mononuclear cell differentiation 406
                      lymphocyte differentiation 360
                        T cell differentiation 265
                          gamma-delta T cell differentiation 12
                            gamma-delta intraepithelial T cell differentiation 2
                              CD8-positive, gamma-delta intraepithelial T cell differentiation 2
paths to the root