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ONTOLOGY REPORT - ANNOTATIONS


Term:CD8-positive, gamma-delta intraepithelial T cell differentiation
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Accession:GO:0002305 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: CD8-positive, gamma-delta intraepithelial T-lymphocyte differentiation
 related_synonym: CD8-positive, gamma-delta intraepithelial T cell development


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CD8-positive, gamma-delta intraepithelial T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr9 C-C motif chemokine receptor 9 acts_upstream_of_or_within ISO MGI:3654108 (MGI:5629467|PMID:25348153) RGD PMID:25348153 MGI:5629467 NCBI chr 8:132,827,325...132,842,130
Ensembl chr 8:132,828,091...132,842,130
JBrowse link
G Gpr18 G protein-coupled receptor 18 acts_upstream_of_or_within ISO MGI:5708707 (MGI:5629467|PMID:25348153) RGD PMID:25348153 MGI:5629467 NCBI chr15:108,323,157...108,326,907
Ensembl chr15:108,323,179...108,326,907
JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in ISO (PMID:18064301) RGD PMID:18064301 NCBI chr 4:163,453,435...163,463,718
Ensembl chr 4:163,458,528...163,463,718
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    immune system process 2913
      leukocyte activation 1069
        lymphocyte activation 883
          T cell activation 529
            T cell differentiation 297
              gamma-delta T cell differentiation 18
                gamma-delta intraepithelial T cell differentiation 3
                  CD8-positive, gamma-delta intraepithelial T cell differentiation 3
Path 2
Term Annotations click to browse term
  biological_process 19599
    developmental process 6753
      anatomical structure development 6178
        multicellular organism development 5617
          system development 5288
            immune system development 1092
              hematopoietic or lymphoid organ development 1026
                hemopoiesis 974
                  leukocyte differentiation 609
                    mononuclear cell differentiation 474
                      lymphocyte differentiation 422
                        T cell differentiation 297
                          gamma-delta T cell differentiation 18
                            gamma-delta intraepithelial T cell differentiation 3
                              CD8-positive, gamma-delta intraepithelial T cell differentiation 3
paths to the root