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ONTOLOGY REPORT - ANNOTATIONS


Term:CD8-positive, gamma-delta intraepithelial T cell differentiation
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Accession:GO:0002305 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: CD8-positive, gamma-delta intraepithelial T-lymphocyte differentiation
 related_synonym: CD8-positive, gamma-delta intraepithelial T cell development


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CD8-positive, gamma-delta intraepithelial T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR9 C-C motif chemokine receptor 9 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5629467|PMID:25348153) Ensembl
MGI
PMID:25348153 GO_REF:0000107 MGI:5629467 NCBI chr 3:45,886,064...45,903,174
Ensembl chr 3:45,886,509...45,903,174
JBrowse link
G GPR18 G protein-coupled receptor 18 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5629467|PMID:25348153) Ensembl
MGI
PMID:25348153 GO_REF:0000107 MGI:5629467 NCBI chr13:99,254,713...99,262,498
Ensembl chr13:99,254,732...99,261,744
JBrowse link
G KLRC1 killer cell lectin like receptor C1 involved_in IDA (PMID:18064301) UniProt PMID:18064301 NCBI chr12:10,441,673...10,454,685
Ensembl chr12:10,442,264...10,454,685
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18532
    immune system process 3145
      leukocyte activation 1091
        lymphocyte activation 903
          T cell activation 569
            T cell differentiation 308
              gamma-delta T cell differentiation 17
                gamma-delta intraepithelial T cell differentiation 3
                  CD8-positive, gamma-delta intraepithelial T cell differentiation 3
Path 2
Term Annotations click to browse term
  biological_process 18532
    developmental process 7217
      anatomical structure development 6540
        multicellular organism development 5911
          system development 5588
            immune system development 1155
              hematopoietic or lymphoid organ development 1085
                hemopoiesis 1036
                  leukocyte differentiation 652
                    mononuclear cell differentiation 507
                      lymphocyte differentiation 451
                        T cell differentiation 308
                          gamma-delta T cell differentiation 17
                            gamma-delta intraepithelial T cell differentiation 3
                              CD8-positive, gamma-delta intraepithelial T cell differentiation 3
paths to the root