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ONTOLOGY REPORT - ANNOTATIONS

Term:CD8-positive, gamma-delta intraepithelial T cell differentiation
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Accession:GO:0002305 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: CD8-positive, gamma-delta intraepithelial T-lymphocyte differentiation
 related_synonym: CD8-positive, gamma-delta intraepithelial T cell development


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CD8-positive, gamma-delta intraepithelial T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR9 C-C motif chemokine receptor 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5629467|PMID:25348153) Ensembl
MGI
Ensembl		 PMID:25348153 GO_REF:0000107 MGI:5629467 NCBI chr20:42,607,024...42,616,823
Ensembl chr20:42,607,024...42,616,823 		JBrowse link
G GPR18 G protein-coupled receptor 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5629467|PMID:25348153) Ensembl
MGI
Ensembl		 PMID:25348153 GO_REF:0000107 MGI:5629467 NCBI chr22:49,288,226...49,294,567
Ensembl chr22:49,288,343...49,289,338 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17428
    immune system process 2348
      leukocyte activation 998
        lymphocyte activation 805
          T cell activation 561
            T cell differentiation 322
              gamma-delta T cell differentiation 17
                gamma-delta intraepithelial T cell differentiation 2
                  CD8-positive, gamma-delta intraepithelial T cell differentiation 2
Path 2
Term Annotations click to browse term
  biological_process 17428
    cellular process 16176
      cellular developmental process 4466
        cell differentiation 4441
          cell development 3157
            hemopoiesis 1035
              leukocyte differentiation 657
                mononuclear cell differentiation 501
                  lymphocyte differentiation 441
                    T cell differentiation 322
                      gamma-delta T cell differentiation 17
                        gamma-delta intraepithelial T cell differentiation 2
                          CD8-positive, gamma-delta intraepithelial T cell differentiation 2
paths to the root