CD8-positive, gamma-delta intraepithelial T cell differentiation - Ontology Report

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Term:	CD8-positive, gamma-delta intraepithelial T cell differentiation	go back to main search page
Accession:	GO:0002305	browse the term
Definition:	The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
Comment:	Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:	exact_synonym:	CD8-positive, gamma-delta intraepithelial T-lymphocyte differentiation
	related_synonym:	CD8-positive, gamma-delta intraepithelial T cell development

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Rat (3) Mouse (3) Human (3) Chinchilla (2) Bonobo (3) Dog (2) Squirrel (2) Pig (3) Green Monkey (3) Naked Mole-rat (2) All
Genes (2)

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CCR9

C-C motif chemokine receptor 9

involved_in
acts_upstream_of_or_within

(PMID:25348153)

GO_REF:0000107

NCBI chr20:42,607,024...42,616,823
Ensembl chr20:42,607,024...42,616,823

G protein-coupled receptor 18

involved_in
acts_upstream_of_or_within

(PMID:25348153)

GO_REF:0000107

NCBI chr22:49,288,226...49,294,567
Ensembl chr22:49,288,343...49,289,338

Term paths to the root

Path 1
Term	Annotations
biological_process	17878
immune system process	2491
leukocyte activation	1022
lymphocyte activation	829
T cell activation	582
T cell differentiation	324
gamma-delta T cell differentiation	16
gamma-delta intraepithelial T cell differentiation	2
CD8-positive, gamma-delta intraepithelial T cell differentiation	2
Path 2
Term	Annotations
biological_process	17878
cellular process	16920
cellular developmental process	4609
cell differentiation	4608
cell development	3263
hemopoiesis	1054
leukocyte differentiation	674
mononuclear cell differentiation	552
lymphocyte differentiation	454
T cell differentiation	324
gamma-delta T cell differentiation	16
gamma-delta intraepithelial T cell differentiation	2
CD8-positive, gamma-delta intraepithelial T cell differentiation	2

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