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ONTOLOGY REPORT - ANNOTATIONS


Term:CD8-positive, gamma-delta intraepithelial T cell differentiation
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Accession:GO:0002305 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: CD8-positive, gamma-delta intraepithelial T-lymphocyte differentiation
 related_synonym: CD8-positive, gamma-delta intraepithelial T cell development


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CD8-positive, gamma-delta intraepithelial T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR9 C-C motif chemokine receptor 9 acts_upstream_of_or_within ISO (MGI:5629467|PMID:25348153) MGI PMID:25348153 MGI:5629467 NCBI chr 3:45,719,655...45,810,964
Ensembl chr 3:46,900,845...46,917,443
JBrowse link
G GPR18 G protein-coupled receptor 18 acts_upstream_of_or_within ISO (MGI:5629467|PMID:25348153) MGI PMID:25348153 MGI:5629467 NCBI chr13:80,423,534...80,427,604
Ensembl chr13:99,562,589...99,563,584
JBrowse link
G LOC100990924 NKG2-A/NKG2-B type II integral membrane protein involved_in ISO (PMID:18064301) UniProt PMID:18064301 NCBI chr12:10,469,351...10,576,060
Ensembl chr12:10,720,723...10,744,046
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12652
    immune system process 2189
      leukocyte activation 863
        lymphocyte activation 696
          T cell activation 482
            T cell differentiation 278
              gamma-delta T cell differentiation 17
                gamma-delta intraepithelial T cell differentiation 3
                  CD8-positive, gamma-delta intraepithelial T cell differentiation 3
Path 2
Term Annotations click to browse term
  biological_process 12652
    developmental process 5902
      anatomical structure development 5505
        multicellular organism development 5033
          system development 4739
            immune system development 989
              hematopoietic or lymphoid organ development 927
                hemopoiesis 879
                  leukocyte differentiation 556
                    mononuclear cell differentiation 429
                      lymphocyte differentiation 378
                        T cell differentiation 278
                          gamma-delta T cell differentiation 17
                            gamma-delta intraepithelial T cell differentiation 3
                              CD8-positive, gamma-delta intraepithelial T cell differentiation 3
paths to the root