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ONTOLOGY REPORT - ANNOTATIONS


Term:CD8-positive, gamma-delta intraepithelial T cell differentiation
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Accession:GO:0002305 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: CD8-positive, gamma-delta intraepithelial T-lymphocyte differentiation
 related_synonym: CD8-positive, gamma-delta intraepithelial T cell development



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CD8-positive, gamma-delta intraepithelial T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr9 C-C motif chemokine receptor 9 acts_upstream_of_or_within ISO MGI:3654108 (MGI:5629467|PMID:25348153) RGD PMID:25348153 MGI:5629467 NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969
JBrowse link
G Gpr18 G protein-coupled receptor 18 acts_upstream_of_or_within ISO MGI:5708707 (MGI:5629467|PMID:25348153) RGD PMID:25348153 MGI:5629467 NCBI chr15:98,997,427...99,001,177
Ensembl chr15:98,997,259...99,001,470
JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in ISO (PMID:18064301) RGD PMID:18064301 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19876
    immune system process 2574
      leukocyte activation 1042
        lymphocyte activation 853
          T cell activation 571
            T cell differentiation 315
              gamma-delta T cell differentiation 17
                gamma-delta intraepithelial T cell differentiation 3
                  CD8-positive, gamma-delta intraepithelial T cell differentiation 3
Path 2
Term Annotations click to browse term
  biological_process 19876
    cellular process 18552
      cellular developmental process 4663
        cell differentiation 4639
          cell development 3236
            hemopoiesis 1039
              leukocyte differentiation 657
                mononuclear cell differentiation 500
                  lymphocyte differentiation 441
                    T cell differentiation 315
                      gamma-delta T cell differentiation 17
                        gamma-delta intraepithelial T cell differentiation 3
                          CD8-positive, gamma-delta intraepithelial T cell differentiation 3
paths to the root